Module Functions 1 "Energy production and conversion:Uncharacterized conserved protein:Lipoate synthase:ATPase components of ABC transporters with duplicated ATPase domains:tmRNA-binding protein:Thioredoxin-like proteins and domains:Uncharacterized conserved protein:Aconitase A:Hydrolases of the alpha/beta superfamily:Transcriptional regulators, similar to M. xanthus CarD:Phosphatidylserine/phosphatidylglycerophosphate/cardiolipin synthases and related enzymes:DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog:Ferritin-like protein:Predicted transcriptional regulators:Predicted transcriptional regulators:Predicted CoA-binding protein:Coenzyme transport and metabolism:Lipid transport and metabolism:Transcription:Posttranslational modification, protein turnover, chaperones:Inorganic ion transport and metabolism:Citrate cycle (TCA cycle):Glycerophospholipid metabolism:Glyoxylate and dicarboxylate metabolism:Carbon fixation pathways in prokaryotes:Lipoic acid metabolism:Porphyrin and chlorophyll metabolism:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:Two-component system:RNA polymerase:General function prediction only:Function unknown:TIGR00049:smpB:TIGR00278:lipA:aconitase_1:rpoN_sigma:Metabolism:Carbohydrate Metabolism:Energy Metabolism:Lipid Metabolism:Metabolism of Cofactors and Vitamins:Genetic Information Processing:Transcription:Environmental Information Processing:Signal Transduction:Global:Metabolism:Energy metabolism:TCA cycle:Transcription:Transcription factors:Protein synthesis:Other:Hypothetical proteins:Conserved:Biosynthesis of cofactors, prosthetic groups, and carriers:Other:Lipoate:Information storage and processing:Cellular processes and signaling:Metabolism:Poorly characterized" 2 "Methyl-accepting chemotaxis protein:Subtilisin-like serine proteases:Uncharacterized bacitracin resistance protein:Zinc metalloprotease (elastase):FOG: PKD repeat:Metal-dependent hydrolase:Response regulator of citrate/malate metabolism:Amino acid transport and metabolism:Transcription:Cell motility:Posttranslational modification, protein turnover, chaperones:Peptidoglycan biosynthesis:Inositol phosphate metabolism:Glycerophospholipid metabolism:Metabolic pathways:Two-component system:Bacterial chemotaxis:General function prediction only:Signal transduction mechanisms:sphingomy:Defense mechanisms:Pathogenesis:Carbohydrate Metabolism:Lipid Metabolism:Glycan Biosynthesis and Metabolism:Environmental Information Processing:Signal Transduction:Cellular Processes:Cell Motility:Global:Metabolism:Cellular processes:Metabolism:Information storage and processing:Cellular processes and signaling:Metabolism:Poorly characterized" 3 "Energy production and conversion:ATP phosphoribosyltransferase:Phosphoribosylformimino-5-aminoimidazole carboxamide ribonucleotide (ProFAR) isomerase:Glutamine amidotransferase:Phosphoribosyl-AMP cyclohydrolase:Phosphoribosyl-ATP pyrophosphohydrolase:Histidinol dehydrogenase:Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase:Thiamine monophosphate synthase:Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2:ABC-type nitrate/sulfonate/bicarbonate transport system, permease component:Glycine/D-amino acid oxidases (deaminating):ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components:Putative transcription activator:ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component:Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM/CutM homologs:Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL homologs:Uncharacterized enzyme of thiazole biosynthesis:Sulfur transfer protein involved in thiamine biosynthesis:Predicted ornithine cyclodeaminase, mu-crystallin homolog:Proline racemase:Amino acid transport and metabolism:Coenzyme transport and metabolism:Transcription:Inorganic ion transport and metabolism:Purine metabolism:Arginine and proline metabolism:Histidine metabolism:Thiamine metabolism:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:ABC transporters:Sulfur relay system:TIGR00007:hisD:hisG:HMP-P_kinase:thiS:IMP_synth_hisH:thiamin_ThiO:adenyl_thiF:histidine_hisI:Amino acid biosynthesis:Metabolism:Metabolism:Global:Membrane Transport:Environmental Information Processing:Folding Sorting and Degradation:Genetic Information Processing:Metabolism of Cofactors and Vitamins:Amino Acid Metabolism:Metabolism:Nucleotide Metabolism:Information storage and processing:Thiamine:Biosynthesis of cofactors, prosthetic groups, and carriers:Histidine family" 4 "Aspartate oxidase:Transcriptional regulators:Uncharacterized protein conserved in bacteria:Uncharacterized protein conserved in bacteria:Uncharacterized protein conserved in bacteria:Coenzyme transport and metabolism:Transcription:Alanine aspartate and glutamate metabolism:Nicotinate and nicotinamide metabolism:Metabolic pathways:Function unknown:nadB:staph_tand_hypo:Pyridine nucleotides:Amino Acid Metabolism:Metabolism of Cofactors and Vitamins:Global:Metabolism:Biosynthesis of cofactors, prosthetic groups, and carriers:Metabolism:Information storage and processing:Metabolism:Poorly characterized" 5 "N-acetylmuramoyl-L-alanine amidase:Putative effector of murein hydrolase:Cell wall/membrane/envelope biogenesis:Cellular processes and signaling" 6 "Energy production and conversion:Preprotein translocase subunit SecY:Transcriptional regulator:Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily):Signal transduction histidine kinase:Predicted xylanase/chitin deacetylase:Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain:Parvulin-like peptidyl-prolyl isomerase:NAD-dependent aldehyde dehydrogenases:Transcriptional regulator:Predicted acyltransferase:Methylase involved in ubiquinone/menaquinone biosynthesis:Permeases:Signal transduction histidine kinase, nitrogen specific:Uncharacterized protein conserved in bacteria:Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain:Signal transduction histidine kinase:Carbohydrate transport and metabolism:Coenzyme transport and metabolism:Transcription:Posttranslational modification, protein turnover, chaperones:Ubiquinone and other terpenoid-quinone biosynthesis:Alanine aspartate and glutamate metabolism:Tyrosine metabolism:Butanoate metabolism:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:Two-component system:Protein export:Bacterial secretion system:General function prediction only:Function unknown:Signal transduction mechanisms:sensory_box:3a0501s007:MenG_MenH_UbiE:Intracellular trafficking, secretion, and vesicular transport:Metabolism:Poorly characterized:Metabolism:Cellular processes and signaling:Information storage and processing:Menaquinone and ubiquinone:Biosynthesis of cofactors, prosthetic groups, and carriers:Protein and peptide secretion and trafficking:Protein fate:Small molecule interactions:Regulatory functions:Metabolism:Global:Signal Transduction:Membrane Transport:Environmental Information Processing:Folding Sorting and Degradation:Genetic Information Processing:Metabolism of Cofactors and Vitamins:Amino Acid Metabolism:Carbohydrate Metabolism" 7 "Energy production and conversion:Acetyltransferases:ABC-type Fe3+-hydroxamate transport system, periplasmic component:Predicted transcriptional regulators:Predicted thioesterase:Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases):Predicted transcriptional regulators:Predicted transcriptional regulators:Cytochrome c, mono- and diheme variants:Transcriptional regulators:Uncharacterized conserved protein:Uncharacterized conserved protein:Transcriptional antiterminator:Protein involved in sex pheromone biosynthesis:Uncharacterized protein conserved in bacteria:Lipid transport and metabolism:Transcription:Inorganic ion transport and metabolism:Tyrosine metabolism:Benzoate degradation:Naphthalene degradation:Aminobenzoate degradation:Ethylbenzene degradation:Limonene and pinene degradation:Microbial metabolism in diverse environments:ABC transporters:Ribosome:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:Function unknown:TIGR00051:rpmH_bact:trehalos_R_Bsub:Protein synthesis:DNA interactions:Regulatory functions:Metabolism:Global:Membrane Transport:Environmental Information Processing:Metabolism:Translation:Genetic Information Processing:Xenobiotics Biodegradation and Metabolism:Metabolism of Terpenoids and Polyketides:General:Amino Acid Metabolism:Information storage and processing:Metabolism:Poorly characterized:Unknown function:Ribosomal proteins: synthesis and modification" 8 "Predicted S-adenosylmethionine-dependent methyltransferase:Superfamily II DNA and RNA helicases:Uncharacterized membrane-associated protein:Signal transduction histidine kinase:Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain:Metal-dependent hydrolases of the beta-lactamase superfamily III:Methylase of chemotaxis methyl-accepting proteins:Predicted metal-dependent hydrolase:D-alanyl-D-alanine carboxypeptidase:Uncharacterized bacitracin resistance protein:Nucleoside permease:Membrane protein involved in the export of O-antigen and teichoic acid:Permeases:Predicted membrane protein:Nucleotide transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:Replication, recombination and repair:Cell wall/membrane/envelope biogenesis:Cell motility:Peptidoglycan biosynthesis:Two-component system:Bacterial chemotaxis:General function prediction only:Function unknown:Signal transduction mechanisms:TIGR00091:RNase_Z:Defense mechanisms:Signal Transduction:Environmental Information Processing:Poorly characterized:Glycan Biosynthesis and Metabolism:Metabolism:Cellular processes and signaling:Metabolism:Information storage and processing:tRNA and rRNA base modification:Protein synthesis:RNA processing:Transcription:Cell Motility:Cellular Processes" 9 "Nicotinate-nucleotide pyrophosphorylase:Glycosyltransferase:Nucleoside-diphosphate-sugar epimerases:Predicted xylanase/chitin deacetylase:Cell division protein FtsI/penicillin-binding protein 2:Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs:Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis/translation initiation factor 2B, gamma/epsilon subunits (eIF-2Bgamma/eIF-2Bepsilon):Amidases related to nicotinamidase:Predicted transcriptional regulators:D-alanyl-D-alanine carboxypeptidase:AraC-type DNA-binding domain-containing proteins:Erythromycin esterase homolog:Uncharacterized enzyme involved in biosynthesis of extracellular polysaccharides:Predicted transcriptional regulator:Uncharacterized conserved protein:Amino acid transport and metabolism:Carbohydrate transport and metabolism:Coenzyme transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:Cell wall/membrane/envelope biogenesis:Galactose metabolism:Starch and sucrose metabolism:Amino sugar and nucleotide sugar metabolism:Nicotinate and nicotinamide metabolism:Metabolic pathways:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:Function unknown:nadC:Poorly characterized:Metabolism:Cellular processes and signaling:Information storage and processing:Pyridine nucleotides:Biosynthesis of cofactors, prosthetic groups, and carriers:Metabolism:Global:Metabolism of Cofactors and Vitamins:Metabolism:Carbohydrate Metabolism" 10 "Transcriptional regulator:Permeases of the drug/metabolite transporter (DMT) superfamily:Parvulin-like peptidyl-prolyl isomerase:Alanine racemase:Predicted SAM-dependent methyltransferases:16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases:Predicted membrane protein:Regulators of stationary/sporulation gene expression:Lysophospholipase:Predicted transcriptional regulator:Uncharacterized protein conserved in bacteria:Amino acid transport and metabolism:Carbohydrate transport and metabolism:Lipid transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:Cell wall/membrane/envelope biogenesis:Posttranslational modification, protein turnover, chaperones:D-Alanine metabolism:Metabolic pathways:Two-component system:General function prediction only:Function unknown:TIGR00093:alr:lp_hng_hel_AbrB:spore_ger_x_C:pip_yhgE_Nterm:Information storage and processing:Biosynthesis and degradation of murein sacculus and peptidoglycan:Cell envelope:Sporulation and germination:Cellular processes:tRNA and rRNA base modification:Protein synthesis:DNA interactions:Regulatory functions:Metabolism:Metabolism:Global:Signal Transduction:Environmental Information Processing:Poorly characterized:Metabolism of Other Amino Acids:Metabolism:Cellular processes and signaling" 11 "Glycosidases:Uncharacterized NAD(FAD)-dependent dehydrogenases:Uncharacterized membrane-associated protein:Beta-lactamase class C and other penicillin binding proteins:Predicted transcriptional regulators:Predicted membrane protein:H+/gluconate symporter and related permeases:Arabinose efflux permease:Amino acid transport and metabolism:Carbohydrate transport and metabolism:Transcription:Starch and sucrose metabolism:Metabolic pathways:General function prediction only:Function unknown:spore_ger_x_C:Defense mechanisms:Cellular processes:Metabolism:Global:Metabolism:Carbohydrate Metabolism:Poorly characterized:Metabolism:Cellular processes and signaling:Information storage and processing:Sporulation and germination" 12 "Uncharacterized conserved protein:Function unknown:SASP_gamma:spore_sspO:Sporulation and germination:Cellular processes:Poorly characterized" 13 "Zn-dependent protease with chaperone function:Uncharacterized conserved protein (some members contain a von Willebrand factor type A (vWA) domain):DNA-binding HTH domain-containing proteins:Uncharacterized protein involved in tellurite resistance:Transcription:Posttranslational modification, protein turnover, chaperones:Inorganic ion transport and metabolism:General function prediction only:Information storage and processing:Poorly characterized:Metabolism:Cellular processes and signaling" 14 "Energy production and conversion:Ribosomal protein S7:Ribosomal protein L1:Transcription antiterminator:Prolyl-tRNA synthetase:Superfamily II DNA and RNA helicases:Predicted GTPase:Heme/copper-type cytochrome/quinol oxidases, subunit 1:Polyribonucleotide nucleotidyltransferase (polynucleotide phosphorylase):Phosphate transport regulator (distant homolog of PhoU):Heme/copper-type cytochrome/quinol oxidases, subunit 2:Heme/copper-type cytochrome/quinol oxidase, subunit 3:Translation, ribosomal structure and biogenesis:Transcription:Replication, recombination and repair:Inorganic ion transport and metabolism:Oxidative phosphorylation:Purine metabolism:Pyrimidine metabolism:Aminoacyl-tRNA biosynthesis:Metabolic pathways:Two-component system:Ribosome:RNA degradation:General function prediction only:small_GTP:proS_fam_II:nusG:rpsG_bact:rplA_bact:QOXA:QoxB:QoxC:polynuc_phos:Unknown function:Energy Metabolism:Nucleotide Metabolism:Genetic Information Processing:Translation:Folding Sorting and Degradation:Environmental Information Processing:Signal Transduction:Global:Metabolism:Energy metabolism:Electron transport:Transcription:Degradation of RNA:Transcription factors:Protein synthesis:tRNA aminoacylation:Ribosomal proteins: synthesis and modification:Metabolism:General:Information storage and processing:Metabolism:Poorly characterized" 15 "Energy production and conversion:Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases:Predicted hydrolase (HAD superfamily):Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities:Choline-glycine betaine transporter:Metal-dependent amidase/aminoacylase/carboxypeptidase:Uncharacterized protein required for formate dehydrogenase activity:SH3 domain protein:Predicted transcriptional regulator:Uncharacterized protein conserved in bacteria:ABC-type uncharacterized transport system, ATPase component:Predicted DNA alkylation repair enzyme:Amino acid transport and metabolism:Nucleotide transport and metabolism:Carbohydrate transport and metabolism:Transcription:Replication, recombination and repair:Cell wall/membrane/envelope biogenesis:Cysteine and methionine metabolism:Arginine and proline metabolism:Selenocompound metabolism:Chloroalkane and chloroalkene degradation:Nitrogen metabolism:Sulfur metabolism:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:General function prediction only:Function unknown:Signal transduction mechanisms:fdhD_narQ:bcct:B_ant_repeat:HAD-SF-IA-v3:amidohydrolases:exospor_lead:Poorly characterized:Energy Metabolism:Amino Acid Metabolism:Metabolism of Other Amino Acids:Xenobiotics Biodegradation and Metabolism:Global:Metabolism:Energy metabolism:Electron transport:Protein fate:Degradation of proteins, peptides, and glycopeptides:Transport and binding proteins:Other:Cellular processes:Sporulation and germination:Unknown function:Enzymes of unknown specificity:Information storage and processing:Cellular processes and signaling:Metabolism:Metabolism" 16 "Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II:Nucleoside-diphosphate-sugar epimerases:Arabinose efflux permease:Uncharacterized protein conserved in bacteria:V8-like Glu-specific endopeptidase:Amino acid transport and metabolism:Carbohydrate transport and metabolism:Lipid transport and metabolism:Cell wall/membrane/envelope biogenesis:Secondary metabolites biosynthesis, transport and catabolism:Function unknown:Cellular processes and signaling:Poorly characterized:Metabolism" 17 "Uncharacterized membrane protein, putative virulence factor:ABC-type antimicrobial peptide transport system, ATPase component:Sortase (surface protein transpeptidase):Cell wall/membrane/envelope biogenesis:General function prediction only:sortase_fam:psiM2_ORF9:spore_II_GA:spore_yqfD:spore_V_B:Defense mechanisms:Cellular processes and signaling:Protein and peptide secretion and trafficking:Protein fate:Poorly characterized:Cellular processes:Sporulation and germination:Mobile and extrachromosomal element functions:Prophage functions" 18 "Energy production and conversion:Glycerol-3-phosphate dehydrogenase:Uncharacterized membrane-associated protein:ABC-type Fe3+-siderophore transport system, permease component:ABC-type antimicrobial peptide transport system, ATPase component:Transcriptional regulator:Transcriptional regulator:N-acetylglucosamine-6-phosphate deacetylase:Membrane transporters of cations and cationic drugs:Predicted membrane protein:Arabinose efflux permease:Predicted membrane protein:Signal transduction histidine kinase:Predicted membrane protein:Uncharacterized protein conserved in bacteria:Carbohydrate transport and metabolism:Transcription:Inorganic ion transport and metabolism:Amino sugar and nucleotide sugar metabolism:Glycerophospholipid metabolism:ABC transporters:Two-component system:Function unknown:Signal transduction mechanisms:nagA:lytR_cpsA_psr:yxeA_fam:Defense mechanisms:Poorly characterized:Carbohydrate Metabolism:Lipid Metabolism:Environmental Information Processing:Membrane Transport:Signal Transduction:Central intermediary metabolism:Amino sugars:Regulatory functions:Other:Hypothetical proteins:Conserved:Information storage and processing:Cellular processes and signaling:Metabolism:Metabolism" 19 "K+ transport systems, NAD-binding component:Signal peptidase I:Cytochrome c biogenesis protein:ATPase components of various ABC-type transport systems, contain duplicated ATPase:Peroxiredoxin:DNA uptake protein and related DNA-binding proteins:Zn-dependent proteases:Lyzozyme M1 (1,4-beta-N-acetylmuramidase):Replication, recombination and repair:Cell wall/membrane/envelope biogenesis:Posttranslational modification, protein turnover, chaperones:Inorganic ion transport and metabolism:ABC transporters:Protein export:General function prediction only:TIGR00426:sigpep_I_bact:Intracellular trafficking, secretion, and vesicular transport:Poorly characterized:Folding Sorting and Degradation:Environmental Information Processing:Membrane Transport:Protein fate:Protein and peptide secretion and trafficking:Cellular processes:DNA transformation:Information storage and processing:Cellular processes and signaling:Metabolism:Genetic Information Processing" 20 "Aspartate/tyrosine/aromatic aminotransferase:Putative intracellular protease/amidase:Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases):Ribose/xylose/arabinose/galactoside ABC-type transport systems, permease components:Sortase and related acyltransferases:Transcriptional regulator:Uncharacterized protein conserved in bacteria:Predicted Rossmann fold nucleotide-binding protein:Uncharacterized conserved protein:Predicted transcriptional regulators:Predicted hydrolases of HD superfamily:Predicted acyltransferase:Leucyl aminopeptidase (aminopeptidase T):Lysophospholipase L1 and related esterases:Uncharacterized protein conserved in bacteria:Membrane-bound metallopeptidase:Cell cycle control, cell division, chromosome partitioning:Amino acid transport and metabolism:Carbohydrate transport and metabolism:Lipid transport and metabolism:Transcription:Cell wall/membrane/envelope biogenesis:Cysteine and methionine metabolism:Phosphonate and phosphinate metabolism:Metabolic pathways:Biosynthesis of secondary metabolites:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:Function unknown:TIGR00730:Amino Acid Metabolism:Metabolism:Poorly characterized:Metabolism:Cellular processes and signaling:Information storage and processing:Conserved:Hypothetical proteins:Metabolism:Global:Metabolism of Other Amino Acids" 21 "Membrane proteins related to metalloendopeptidases:Methyl-accepting chemotaxis protein:Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases):Transposase and inactivated derivatives:SH3 domain protein:Zinc metalloprotease (elastase):ABC-type phosphate/phosphonate transport system, permease component:Uncharacterized protein conserved in bacteria:Ornithine/acetylornithine aminotransferase:Amino acid transport and metabolism:Lipid transport and metabolism:Replication, recombination and repair:Cell wall/membrane/envelope biogenesis:Cell motility:Inorganic ion transport and metabolism:Fatty acid biosynthesis:Arginine and proline metabolism:Biosynthesis of unsaturated fatty acids:Metabolic pathways:Biosynthesis of secondary metabolites:ABC transporters:Two-component system:Bacterial chemotaxis:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:Function unknown:Signal transduction mechanisms:PhnE:spore_safA:Transport and binding proteins:Metabolism:Global:Cell Motility:Cellular Processes:Metabolism:Signal Transduction:Membrane Transport:Environmental Information Processing:Amino Acid Metabolism:Cellular processes:Lipid Metabolism:Sporulation and germination:Information storage and processing:Cellular processes and signaling:Metabolism:Poorly characterized:Anions" 22 "Energy production and conversion:Isoleucyl-tRNA synthetase:Geranylgeranyl pyrophosphate synthase:Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases:Metal-dependent proteases with possible chaperone activity:Prolipoprotein diacylglyceryltransferase:Acetyl-CoA carboxylase beta subunit:Acetyl-CoA carboxylase alpha subunit:Pyruvate carboxylase:Predicted rRNA methylase:4-diphosphocytidyl-2-methyl-D-erithritol synthase:Nicotinic acid phosphoribosyltransferase:Transcriptional accessory protein:Predicted membrane protein:Protein involved in sex pheromone biosynthesis:Integral membrane protein (PIN domain superfamily):Coenzyme transport and metabolism:Lipid transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:Cell wall/membrane/envelope biogenesis:Posttranslational modification, protein turnover, chaperones:Citrate cycle (TCA cycle):Fatty acid biosynthesis:Valine leucine and isoleucine biosynthesis:Pyruvate metabolism:Propanoate metabolism:Carbon fixation pathways in prokaryotes:Nicotinate and nicotinamide metabolism:Terpenoid backbone biosynthesis:Aminoacyl-tRNA biosynthesis:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:General function prediction only:Function unknown:gatA:gcp_kae1:ileS:ispD:tly:accA:accD:lgt:pyruv_carbox:Information storage and processing:Carbohydrate Metabolism:Energy Metabolism:Lipid Metabolism:Amino Acid Metabolism:Metabolism of Cofactors and Vitamins:Metabolism of Terpenoids and Polyketides:Genetic Information Processing:Translation:Global:Metabolism:Energy metabolism:Glycolysis/gluconeogenesis:Fatty acid and phospholipid metabolism:Biosynthesis:Protein synthesis:tRNA aminoacylation:Protein fate:Degradation of proteins, peptides, and glycopeptides:Protein modification and repair:Unknown function:General:Biosynthesis of cofactors, prosthetic groups, and carriers:Other:Metabolism:Cellular processes and signaling:Metabolism:Poorly characterized" 23 "Uncharacterized conserved protein:Predicted amidohydrolase:Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2:Zn-dependent hydrolases, including glyoxylases:ABC-type dipeptide/oligopeptide/nickel transport systems, permease components:ADP-ribose pyrophosphatase:Predicted GTPases:Predicted ATPase related to phosphate starvation-inducible protein PhoH:Carbon starvation protein, predicted membrane protein:Uncharacterized small protein:Penicillin V acylase and related amidases:Predicted acetyltransferase:ABC-type oligopeptide transport system, periplasmic component:Amino acid transport and metabolism:Nucleotide transport and metabolism:Coenzyme transport and metabolism:Cell wall/membrane/envelope biogenesis:Inorganic ion transport and metabolism:Secondary bile acid biosynthesis:Metabolic pathways:ABC transporters:Sulfur relay system:General function prediction only:Function unknown:Signal transduction mechanisms:TIGR00157:Environmental Information Processing:Folding Sorting and Degradation:Genetic Information Processing:Poorly characterized:Lipid Metabolism:Metabolism:Metabolism:Cellular processes and signaling:Translation factors:Protein synthesis:Metabolism:Global:Membrane Transport" 24 "Cell division protein FtsI/penicillin-binding protein 2:Predicted acetyltransferase involved in intracellular survival and related acetyltransferases:Cell wall/membrane/envelope biogenesis:General function prediction only:SASP_H:spore_ger_x_C:Poorly characterized:Cellular processes and signaling:Sporulation and germination:Cellular processes" 25 "Fructose-2,6-bisphosphatase:Predicted hydrolases of the HAD superfamily:Putative transcription activator:Membrane protein TerC, possibly involved in tellurium resistance:ABC-type antimicrobial peptide transport system, ATPase component:Phosphatidylserine/phosphatidylglycerophosphate/cardiolipin synthases and related enzymes:DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog:Predicted nucleotide kinase:D-alanyl-D-alanine carboxypeptidase:Alkaline phosphatase:FOG: GGDEF domain:Uncharacterized conserved protein:Predicted phage phi-C31 gp36 major capsid-like protein:Predicted permease, DMT superfamily:Nucleotide transport and metabolism:Carbohydrate transport and metabolism:Lipid transport and metabolism:Transcription:Cell wall/membrane/envelope biogenesis:Inorganic ion transport and metabolism:Glycolysis / Gluconeogenesis:Peptidoglycan biosynthesis:Glycerophospholipid metabolism:Aminobenzoate degradation:Methane metabolism:Thiamine metabolism:Folate biosynthesis:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:Two-component system:RNA polymerase:General function prediction only:Function unknown:Signal transduction mechanisms:GGDEF:spore_ger_x_C:sigma70-ECF:R_switched_YjbE:Defense mechanisms:Signal Transduction:Environmental Information Processing:Transcription:Genetic Information Processing:Xenobiotics Biodegradation and Metabolism:Metabolism of Cofactors and Vitamins:Glycan Biosynthesis and Metabolism:Lipid Metabolism:Energy Metabolism:Cellular processes:Carbohydrate Metabolism:Sporulation and germination:Signal transduction:Other:Information storage and processing:Cellular processes and signaling:Metabolism:Poorly characterized:Metabolism:Metabolism:Global" 26 "2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway):Pyrroline-5-carboxylate reductase:Glycosyltransferases involved in cell wall biogenesis:NTP pyrophosphohydrolases including oxidative damage repair enzymes:Amidases related to nicotinamidase:Erythromycin esterase homolog:Uncharacterized conserved protein:Putative Ser protein kinase:Alpha-tubulin suppressor and related RCC1 domain-containing proteins:Cell cycle control, cell division, chromosome partitioning:Amino acid transport and metabolism:Replication, recombination and repair:Cell wall/membrane/envelope biogenesis:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:Function unknown:Signal transduction mechanisms:Cytoskeleton:Information storage and processing:Poorly characterized:Metabolism:Cellular processes and signaling" 27 "Energy production and conversion:Predicted metal-dependent hydrolase:Peroxiredoxin:Predicted permease:Membrane-associated phospholipid phosphatase:Permeases of the drug/metabolite transporter (DMT) superfamily:UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase:ABC-type multidrug transport system, ATPase component:Uncharacterized conserved protein:L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases:Uncharacterized conserved protein:Predicted membrane-associated HD superfamily hydrolase:Glutaminase:Putative glucose uptake permease:Amino acid transport and metabolism:Carbohydrate transport and metabolism:Lipid transport and metabolism:Cell wall/membrane/envelope biogenesis:Posttranslational modification, protein turnover, chaperones:Alanine aspartate and glutamate metabolism:Arginine and proline metabolism:D-Glutamine and D-glutamate metabolism:Peptidoglycan biosynthesis:Terpenoid backbone biosynthesis:Nitrogen metabolism:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:ABC transporters:General function prediction only:Function unknown:TIGR00043:HDIG:murG:IPP_isom_2:Gln_ase:Defense mechanisms:Protein synthesis:Amino acids and amines:Energy metabolism:Metabolism:Global:Metabolism:Membrane Transport:Environmental Information Processing:Metabolism of Terpenoids and Polyketides:Glycan Biosynthesis and Metabolism:Metabolism of Other Amino Acids:Amino Acid Metabolism:Biosynthesis of cofactors, prosthetic groups, and carriers:Energy Metabolism:Other:Cell envelope:Biosynthesis and degradation of murein sacculus and peptidoglycan:Cellular processes and signaling:Metabolism:Poorly characterized:Other" 28 "Energy production and conversion:Purine nucleoside phosphorylase:Enolase:Thymidine phosphorylase:Superfamily II DNA helicase:Multimeric flavodoxin WrbA:Small-conductance mechanosensitive channel:Predicted transcriptional regulators:Purine-nucleoside phosphorylase:Phosphopentomutase:Predicted transcriptional regulators:DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog:Acetyltransferases, including N-acetylases of ribosomal proteins:Predicted small molecule binding protein (contains 3H domain):Transcriptional regulators:Tartrate dehydratase alpha subunit/Fumarate hydratase class I, N-terminal domain:Regulators of stationary/sporulation gene expression:ABC-type molybdate transport system, permease component:Uncharacterized protein conserved in bacteria:Nucleotide transport and metabolism:Carbohydrate transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:Replication, recombination and repair:Cell wall/membrane/envelope biogenesis:Inorganic ion transport and metabolism:Glycolysis / Gluconeogenesis:Citrate cycle (TCA cycle):Pentose phosphate pathway:Purine metabolism:Pyrimidine metabolism:Methane metabolism:Carbon fixation pathways in prokaryotes:Nicotinate and nicotinamide metabolism:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:ABC transporters:Two-component system:RNA degradation:RNA polymerase:General function prediction only:Function unknown:deoD:parB_part:recQ_fam:ttdA_fumA_fumB:eno:lp_hng_hel_AbrB:TIGR01440:deoB:PNPH-PUNA-XAPA:modB_ABC:rpoN_sigma:Y_phosphoryl:Cellular processes and signaling:Metabolism:Poorly characterized:Metabolism:Global:Signal Transduction:Metabolism:Membrane Transport:Environmental Information Processing:Folding Sorting and Degradation:Transcription:Genetic Information Processing:Metabolism of Cofactors and Vitamins:Nucleotide Metabolism:Energy Metabolism:Carbohydrate Metabolism:Energy metabolism:Glycolysis/gluconeogenesis:Purines, pyrimidines, nucleosides, and nucleotides:Other:Salvage of nucleosides and nucleotides:Regulatory functions:DNA interactions:DNA metabolism:DNA replication, recombination, and repair:Transcription:Transcription factors:Transport and binding proteins:Anions:Hypothetical proteins:Conserved:Information storage and processing" 29 "EMAP domain:Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily):Co/Zn/Cd efflux system component:Acetyltransferases, including N-acetylases of ribosomal proteins:D-alanyl-D-alanine carboxypeptidase:Dioxygenases related to 2-nitropropane dioxygenase:Lysophospholipase:Uncharacterized protein conserved in bacteria:Uncharacterized conserved protein:Lipid transport and metabolism:Translation, ribosomal structure and biogenesis:Cell wall/membrane/envelope biogenesis:Inorganic ion transport and metabolism:Nitrogen metabolism:General function prediction only:Function unknown:CDF:chap_CsaA:Transport and binding proteins:Protein and peptide secretion and trafficking:Protein fate:Poorly characterized:Energy Metabolism:Metabolism:Metabolism:Cellular processes and signaling:Information storage and processing:Cations and iron carrying compounds" 30 "Transcriptional regulator:Glycine/D-amino acid oxidases (deaminating):Predicted xylanase/chitin deacetylase:Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs:N-acetylglutamate synthase and related acetyltransferases:Flagellar motor component:Flagellar motor protein:Transcriptional regulators:Predicted transcriptional regulator:Predicted membrane protein:Predicted transcriptional regulator with C-terminal CBS domains:Predicted membrane protein:Response regulator of citrate/malate metabolism:Amino acid transport and metabolism:Carbohydrate transport and metabolism:Transcription:Cell motility:Tyrosine metabolism:Benzoate degradation:Naphthalene degradation:Aminobenzoate degradation:Ethylbenzene degradation:Limonene and pinene degradation:Microbial metabolism in diverse environments:Two-component system:Bacterial chemotaxis:Flagellar assembly:Function unknown:Signal transduction mechanisms:spore_ybaN_pdaB:T7_EssB:T7_EssCb_Firm:Metabolism:Metabolism:Global:Cell Motility:Cellular Processes:Signal Transduction:Environmental Information Processing:Xenobiotics Biodegradation and Metabolism:Metabolism of Terpenoids and Polyketides:Protein and peptide secretion and trafficking:Amino Acid Metabolism:Cellular processes:Sporulation and germination:Information storage and processing:Cellular processes and signaling:Metabolism:Poorly characterized:Protein fate" 31 "Uncharacterized membrane protein:Predicted xylanase/chitin deacetylase:Aspartate ammonia-lyase:Phosphatidylserine synthase:Acetyltransferases, including N-acetylases of ribosomal proteins:Predicted transcriptional regulators:Protein affecting phage T7 exclusion by the F plasmid:Predicted acetyltransferase:Uncharacterized protein conserved in bacteria:Amino acid transport and metabolism:Carbohydrate transport and metabolism:Lipid transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:Alanine aspartate and glutamate metabolism:Glycine serine and threonine metabolism:Arginine and proline metabolism:Tyrosine metabolism:Benzoate degradation:Glycerophospholipid metabolism:Dioxin degradation:Naphthalene degradation:Aminobenzoate degradation:Ethylbenzene degradation:Limonene and pinene degradation:Nitrogen metabolism:Metabolic pathways:Microbial metabolism in diverse environments:General function prediction only:Function unknown:pssA:aspA:spore_pdaA:Information storage and processing:Energy Metabolism:Lipid Metabolism:Amino Acid Metabolism:Metabolism of Terpenoids and Polyketides:Xenobiotics Biodegradation and Metabolism:Global:Metabolism:Energy metabolism:Amino acids and amines:Fatty acid and phospholipid metabolism:Biosynthesis:Cellular processes:Sporulation and germination:Metabolism:Metabolism:Poorly characterized" 32 "Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase]:ATP phosphoribosyltransferase:Ketol-acid reductoisomerase:3-isopropylmalate dehydratase large subunit:3-isopropylmalate dehydratase small subunit:Phosphoribosylformimino-5-aminoimidazole carboxamide ribonucleotide (ProFAR) isomerase:Imidazoleglycerol-phosphate synthase:Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase:Glutamine amidotransferase:Isopropylmalate/homocitrate/citramalate synthases:Dihydroxyacid dehydratase/phosphogluconate dehydratase:Phosphoribosyl-AMP cyclohydrolase:Phosphoribosyl-ATP pyrophosphohydrolase:Histidinol dehydrogenase:Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase:Acetolactate synthase, small (regulatory) subunit:Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2:ABC-type nitrate/sulfonate/bicarbonate transport system, permease component:Glycine/D-amino acid oxidases (deaminating):Putative transcription activator:Threonine dehydratase:Uncharacterized enzyme of thiazole biosynthesis:Sulfur transfer protein involved in thiamine biosynthesis:Amino acid transport and metabolism:Carbohydrate transport and metabolism:Coenzyme transport and metabolism:Transcription:Inorganic ion transport and metabolism:Glycine serine and threonine metabolism:Valine leucine and isoleucine degradation:Valine leucine and isoleucine biosynthesis:Histidine metabolism:Pyruvate metabolism:Butanoate metabolism:C5-Branched dibasic acid metabolism:Thiamine metabolism:Pantothenate and CoA biosynthesis:Metabolic pathways:Biosynthesis of secondary metabolites:ABC transporters:Sulfur relay system:TIGR00007:hisD:hisG:HMP-P_kinase:ilvD:acolac_lg:acolac_sm:leuC:leuD:ilvC:hisF:leuA_bact:ilvE_I:thiS:IMP_synth_hisH:THD1:thiamin_ThiO:adenyl_thiF:histidine_hisI:Information storage and processing:Thiamine:Biosynthesis of cofactors, prosthetic groups, and carriers:Histidine family:Pyruvate family:Amino acid biosynthesis:Metabolism:Global:Metabolism:Membrane Transport:Environmental Information Processing:Folding Sorting and Degradation:Genetic Information Processing:Metabolism of Cofactors and Vitamins:Amino Acid Metabolism:Metabolism:Carbohydrate Metabolism" 33 "Energy production and conversion:Lactoylglutathione lyase and related lyases:Protein-tyrosine-phosphatase:Predicted esterase:Rhodanese-related sulfurtransferase:Predicted transcriptional regulators:Nitroreductase:Arsenite efflux pump ACR3 and related permeases:GTP cyclohydrolase II:Acyl carrier protein phosphodiesterase:Putative copper export protein:Predicted transcriptional regulators:Predicted redox protein, regulator of disulfide bond formation:Transcriptional regulators:Predicted transcriptional regulator:Pyrimidine reductase, riboflavin biosynthesis:Uncharacterized conserved protein:Putative NADPH-quinone reductase (modulator of drug activity B):Predicted membrane protein:Uncharacterized protein conserved in bacteria:Predicted ester cyclase:Amino acid transport and metabolism:Coenzyme transport and metabolism:Lipid transport and metabolism:Transcription:Posttranslational modification, protein turnover, chaperones:Inorganic ion transport and metabolism:Riboflavin metabolism:Metabolic pathways:General function prediction only:Function unknown:Signal transduction mechanisms:ribD_Cterm:acr3:arsC_pI258_fam:organ_hyd_perox:Metabolism of Cofactors and Vitamins:Poorly characterized:Metabolism:Cellular processes and signaling:Information storage and processing:Detoxification:Cellular processes:Anions:Transport and binding proteins:Metabolism:Global:Metabolism" 34 "Dihydrofolate reductase:Pyrroline-5-carboxylate reductase:Predicted hydrolase (HAD superfamily):Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases):Acetyltransferases, including N-acetylases of ribosomal proteins:Uncharacterized protein conserved in bacteria:Uncharacterized vancomycin resistance protein:Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain:Amino acid transport and metabolism:Coenzyme transport and metabolism:Lipid transport and metabolism:Translation, ribosomal structure and biogenesis:Fatty acid biosynthesis:Arginine and proline metabolism:Tyrosine metabolism:Benzoate degradation:Naphthalene degradation:Aminobenzoate degradation:Ethylbenzene degradation:Limonene and pinene degradation:Biosynthesis of unsaturated fatty acids:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:Function unknown:Signal transduction mechanisms:proC:sensory_box:HAD-SF-IA-v3:Defense mechanisms:Information storage and processing:Glutamate family:Amino acid biosynthesis:Enzymes of unknown specificity:Metabolism:Unknown function:Small molecule interactions:Regulatory functions:Global:Metabolism:Xenobiotics Biodegradation and Metabolism:Metabolism of Terpenoids and Polyketides:Amino Acid Metabolism:Cellular processes and signaling:Lipid Metabolism:Metabolism:Poorly characterized" 35 "Energy production and conversion:Hydrogenase maturation factor:NADPH:quinone reductase and related Zn-dependent oxidoreductases:Uncharacterized membrane protein:Posttranslational modification, protein turnover, chaperones:General function prediction only:Function unknown:hypE:spore_III_D:Cellular processes and signaling:Poorly characterized:Sporulation and germination:Cellular processes:Metabolism" 36 "Molecular chaperone (small heat shock protein):Uncharacterized conserved protein:Posttranslational modification, protein turnover, chaperones:Function unknown:spore_ytfJ:SASP_tlp:SASP_sspI:Cellular processes and signaling:Poorly characterized:Sporulation and germination:Cellular processes" 37 "Predicted phosphatase/phosphohexomutase:Predicted permeases:UDP-N-acetylmuramate dehydrogenase:Metal-dependent hydrolases of the beta-lactamase superfamily III:Uncharacterized conserved protein:Protein-disulfide isomerase:Glycerol-3-phosphate responsive antiterminator (mRNA-binding):Large-conductance mechanosensitive channel:Cell division protein:Predicted ATPase involved in cell division:Uncharacterized protein conserved in bacteria:Predicted membrane protein:Uncharacterized protein conserved in bacteria:Predicted permease, DMT superfamily:Cell cycle control, cell division, chromosome partitioning:Transcription:Cell wall/membrane/envelope biogenesis:Posttranslational modification, protein turnover, chaperones:Amino sugar and nucleotide sugar metabolism:Peptidoglycan biosynthesis:Metabolic pathways:ABC transporters:General function prediction only:Function unknown:murB:mscL:HAD-SF-IA-v3:RNase_Z:FtsE:Biosynthesis and degradation of murein sacculus and peptidoglycan:Carbohydrate Metabolism:Glycan Biosynthesis and Metabolism:Environmental Information Processing:Membrane Transport:Global:Metabolism:Transcription:RNA processing:Cellular processes:Cell division:Adaptations to atypical conditions:Unknown function:Enzymes of unknown specificity:Cell envelope:Metabolism:Information storage and processing:Cellular processes and signaling:Poorly characterized" 38 "Nucleoside-diphosphate-sugar epimerases:ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components:Na+/alanine symporter:ABC-type multidrug transport system, ATPase component:Cold shock proteins:Glutaminase:Zinc metalloprotease (elastase):Amino acid transport and metabolism:Carbohydrate transport and metabolism:Transcription:Cell wall/membrane/envelope biogenesis:Inorganic ion transport and metabolism:Alanine aspartate and glutamate metabolism:Arginine and proline metabolism:Bisphenol degradation:D-Glutamine and D-glutamate metabolism:Polycyclic aromatic hydrocarbon degradation:Aminobenzoate degradation:Limonene and pinene degradation:Nitrogen metabolism:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:ABC transporters:Two-component system:agcS:2A0309:LPXTG_anchor:Gln_ase:Defense mechanisms:Amino acids, peptides and amines:Energy Metabolism:Amino Acid Metabolism:Metabolism of Other Amino Acids:Metabolism of Terpenoids and Polyketides:Xenobiotics Biodegradation and Metabolism:Environmental Information Processing:Membrane Transport:Signal Transduction:Global:Metabolism:Energy metabolism:Amino acids and amines:Transport and binding proteins:Metabolism:Cell envelope:Other:Information storage and processing:Cellular processes and signaling:Metabolism" 39 "Ribosomal protein S12:Ribosomal protein S7:Ribosomal protein S10:Ribosomal protein L3:Ribosomal protein L4:Ribosomal protein L23:Ribosomal protein L2:Ribosomal protein L22:Ribosomal protein S3:Ribosomal protein S19:Ribosomal protein HS6-type (S12/L30/L7a):Translation, ribosomal structure and biogenesis:Ribosome:rpsL_bact:rpsC_bact:rpsG_bact:rplV_bact:rpsJ_bact:rpsS_bact:rplB_bact:L3_bact:rplD_bact:Ribosomal proteins: synthesis and modification:Translation:Protein synthesis:Genetic Information Processing:Information storage and processing" 40 "Energy production and conversion:ABC-type transport system involved in Fe-S cluster assembly, ATPase component:Molecular chaperone:Chaperonin GroEL (HSP60 family):DnaJ-class molecular chaperone with C-terminal Zn finger domain:Selenocysteine lyase:Molecular chaperone GrpE (heat shock protein):ABC-type transport system involved in Fe-S cluster assembly, permease component:NifU homolog involved in Fe-S cluster formation:Transcriptional regulator of heat shock gene:Predicted metal-sulfur cluster biosynthetic enzyme:Truncated hemoglobins:Predicted dithiol-disulfide isomerase involved in polyketide biosynthesis:Uncharacterized protein conserved in bacteria:Amino acid transport and metabolism:Transcription:Posttranslational modification, protein turnover, chaperones:Selenocompound metabolism:Thiamine metabolism:Metabolic pathways:RNA degradation:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:Function unknown:hrcA:sufC:sufS:sufD:SUF_scaf_2:GroEL:DnaJ_bact:prok_dnaK:Poorly characterized:Metabolism:Cellular processes and signaling:Information storage and processing:Other:Biosynthesis of cofactors, prosthetic groups, and carriers:Protein folding and stabilization:Protein fate:DNA interactions:Regulatory functions:Metabolism:Metabolism:Global:Folding Sorting and Degradation:Genetic Information Processing:Metabolism of Cofactors and Vitamins:Metabolism of Other Amino Acids" 41 "Acetyltransferase (isoleucine patch superfamily):5-formyltetrahydrofolate cyclo-ligase:Uncharacterized conserved protein:DNA repair exonuclease:Superfamily II DNA/RNA helicases, SNF2 family:rRNA methylases:Rhodanese-related sulfurtransferase:Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain:DNA polymerase III, epsilon subunit and related 3'-5' exonucleases:Putative threonine efflux protein:DNA polymerase III, delta subunit:Predicted transcriptional regulators:Transcriptional regulators:Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain:Septum formation initiator:Sugar diacid utilization regulator:Predicted membrane protein:Signal transduction histidine kinase:Cell cycle control, cell division, chromosome partitioning:Amino acid transport and metabolism:Coenzyme transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:Replication, recombination and repair:Inorganic ion transport and metabolism:Purine metabolism:Pyrimidine metabolism:One carbon pool by folate:Metabolic pathways:Two-component system:DNA replication:Mismatch repair:Homologous recombination:General function prediction only:Function unknown:Signal transduction mechanisms:dnaq:sbcd:TIGR01033:holA:MTHFS_bact:Cellular processes and signaling:Nucleotide Metabolism:Metabolism of Cofactors and Vitamins:Genetic Information Processing:Replication and Repair:Environmental Information Processing:Signal Transduction:Global:Metabolism:Central intermediary metabolism:One-carbon metabolism:Regulatory functions:DNA interactions:DNA metabolism:Degradation of DNA:DNA replication, recombination, and repair:Information storage and processing:Metabolism:Metabolism:Poorly characterized" 42 "Ca2+/H+ antiporter:Transcriptional regulator:V8-like Glu-specific endopeptidase:Phage-related holin (Lysis protein):Amino acid transport and metabolism:Transcription:Inorganic ion transport and metabolism:General function prediction only:lytR_cpsA_psr:cax:holin_tox_secr:spore_ytfJ:Information storage and processing:Metabolism:Poorly characterized:Cellular processes:Sporulation and germination:Transport and binding proteins:Other:Regulatory functions:Cations and iron carrying compounds:Mobile and extrachromosomal element functions:Prophage functions" 43 "Energy production and conversion:Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase]:Malate/lactate dehydrogenases:Trk-type K+ transport systems, membrane components:Citrate synthase:ATPases involved in chromosome partitioning:Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component, and related enzymes:Isocitrate dehydrogenases:2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, and related enzymes:Superoxide dismutase:Predicted 6-phosphogluconate dehydrogenase:Threonine dehydrogenase and related Zn-dependent dehydrogenases:Sugar (pentulose and hexulose) kinases:Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily:Uncharacterized protein required for formate dehydrogenase activity:Uncharacterized proteins involved in stress response, homologs of TerZ and putative cAMP-binding protein CABP1:Uncharacterized conserved protein:H+/gluconate symporter and related permeases:Molybdenum cofactor biosynthesis enzyme:Uncharacterized protein involved in copper resistance:Uncharacterized anaerobic dehydrogenase:Alpha-acetolactate decarboxylase:Uncharacterized conserved protein:Cell cycle control, cell division, chromosome partitioning:Amino acid transport and metabolism:Carbohydrate transport and metabolism:Coenzyme transport and metabolism:Cell wall/membrane/envelope biogenesis:Inorganic ion transport and metabolism:Citrate cycle (TCA cycle):Pentose phosphate pathway:Valine leucine and isoleucine biosynthesis:Lysine degradation:Tryptophan metabolism:Glutathione metabolism:Pyruvate metabolism:Glyoxylate and dicarboxylate metabolism:Butanoate metabolism:C5-Branched dibasic acid metabolism:Methane metabolism:Carbon fixation pathways in prokaryotes:Pantothenate and CoA biosynthesis:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:Sulfur relay system:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:Function unknown:Signal transduction mechanisms:fdhD_narQ:prok_nadp_idh:2oxo_dh_E1:gntP:gnd_rel:2a38:eps_fam:acetolac_decarb:gntK_FGGY:sucB:Fdh-alpha:MalateDH_bact:cit_synth_II:acolac_catab:moaA:Poorly characterized:Carbohydrate Metabolism:Energy Metabolism:Amino Acid Metabolism:Metabolism of Other Amino Acids:Metabolism of Cofactors and Vitamins:Genetic Information Processing:Folding Sorting and Degradation:Global:Metabolism:Energy metabolism:Electron transport:Fermentation:Pentose phosphate pathway:TCA cycle:Sugars:Transport and binding proteins:Carbohydrates, organic alcohols, and acids:Cations and iron carrying compounds:Biosynthesis of cofactors, prosthetic groups, and carriers:Molybdopterin:Cellular processes and signaling:Metabolism:Metabolism" 44 "NTP pyrophosphohydrolases including oxidative damage repair enzymes:Amidases related to nicotinamidase:DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog:Predicted transcriptional regulators:Arabinose efflux permease:Predicted amino acid aldolase or racemase:Amino acid transport and metabolism:Carbohydrate transport and metabolism:Transcription:Replication, recombination and repair:Tyrosine metabolism:Benzoate degradation:Naphthalene degradation:Aminobenzoate degradation:Ethylbenzene degradation:Limonene and pinene degradation:Microbial metabolism in diverse environments:RNA polymerase:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:sigma70-ECF:Poorly characterized:Metabolism:Information storage and processing:Metabolism:Metabolism:Global:Transcription:Genetic Information Processing:Xenobiotics Biodegradation and Metabolism:Metabolism of Terpenoids and Polyketides:Amino Acid Metabolism" 45 "DNA repair exonuclease:DNA polymerase I - 3'-5' exonuclease and polymerase domains:DNA or RNA helicases of superfamily II:Transcription:Replication, recombination and repair:Purine metabolism:Pyrimidine metabolism:Metabolic pathways:DNA replication:Base excision repair:Nucleotide excision repair:Homologous recombination:Metabolism:Information storage and processing:Global:Metabolism:Replication and Repair:Genetic Information Processing:Nucleotide Metabolism" 46 "Histidyl-tRNA synthetase:Ribosomal protein L33:Sugar phosphate isomerases/epimerases:Uncharacterized proteins, homologs of microcin C7 resistance protein MccF:Uncharacterized conserved protein:ATP phosphoribosyltransferase involved in histidine biosynthesis:Siderophore synthetase component:Amino acid transport and metabolism:Carbohydrate transport and metabolism:Translation, ribosomal structure and biogenesis:Histidine metabolism:Aminoacyl-tRNA biosynthesis:Metabolic pathways:Biosynthesis of secondary metabolites:Ribosome:Secondary metabolites biosynthesis, transport and catabolism:Function unknown:hisS:hisZ_biosyn_reg:rpmG_bact:B_ant_repeat:spore_YlmC_YmxH:exospor_lead:TQXA_dom:Defense mechanisms:Metabolism:Poorly characterized:Metabolism:Global:Metabolism:Translation:Genetic Information Processing:Amino Acid Metabolism:Protein synthesis:tRNA aminoacylation:Ribosomal proteins: synthesis and modification:Cellular processes:Sporulation and germination:Amino acid biosynthesis:Histidine family:Information storage and processing:Cellular processes and signaling" 47 "Energy production and conversion:NAD synthase:Predicted transcriptional regulators:Signal peptidase I:Nitroreductase:ADP-ribose pyrophosphatase:Cellulase M and related proteins:Beta-lactamase class C and other penicillin binding proteins:Transcriptional regulators:Phosphopantetheinyl transferase:Formate/nitrite family of transporters:Uncharacterized protein conserved in bacteria:Predicted membrane protein:Uncharacterized protein involved in copper resistance:Nucleotide transport and metabolism:Carbohydrate transport and metabolism:Coenzyme transport and metabolism:Transcription:Inorganic ion transport and metabolism:Nicotinate and nicotinamide metabolism:Nitrogen metabolism:Metabolic pathways:Protein export:Function unknown:nadE:sigpep_I_bact:Intracellular trafficking, secretion, and vesicular transport:Defense mechanisms:Global:Folding Sorting and Degradation:Genetic Information Processing:Metabolism of Cofactors and Vitamins:Cellular processes and signaling:Energy Metabolism:Metabolism:Poorly characterized:Metabolism:Information storage and processing:Pyridine nucleotides:Biosynthesis of cofactors, prosthetic groups, and carriers:Protein and peptide secretion and trafficking:Protein fate:Metabolism" 48 "Energy production and conversion:Folylpolyglutamate synthase:Glutathione peroxidase:Thioredoxin reductase:Alanine dehydrogenase:Permeases of the drug/metabolite transporter (DMT) superfamily:Metal-dependent hydrolases of the beta-lactamase superfamily III:Predicted transcriptional regulators:Glycosyl transferases, related to UDP-glucuronosyltransferase:Uncharacterized enzyme involved in biosynthesis of extracellular polysaccharides:Uncharacterized conserved protein:Uncharacterized anaerobic dehydrogenase:ABC-type branched-chain amino acid transport system, permease component:Amino acid transport and metabolism:Carbohydrate transport and metabolism:Coenzyme transport and metabolism:Transcription:Posttranslational modification, protein turnover, chaperones:Oxidative phosphorylation:Pyrimidine metabolism:Alanine aspartate and glutamate metabolism:Taurine and hypotaurine metabolism:Glutathione metabolism:Arachidonic acid metabolism:Glyoxylate and dicarboxylate metabolism:Methane metabolism:Folate biosynthesis:Metabolic pathways:Microbial metabolism in diverse environments:ABC transporters:General function prediction only:Function unknown:alaDH:MGT:folC:Fdh-alpha:Global:Membrane Transport:Environmental Information Processing:Metabolism of Cofactors and Vitamins:Metabolism of Other Amino Acids:Amino Acid Metabolism:Nucleotide Metabolism:Metabolism:Lipid Metabolism:Energy Metabolism:Carbohydrate Metabolism:Energy metabolism:Amino acids and amines:Cellular processes:Toxin production and resistance:Biosynthesis of cofactors, prosthetic groups, and carriers:Folic acid:Information storage and processing:Cellular processes and signaling:Metabolism:Poorly characterized:Metabolism" 49 "Energy production and conversion:Shikimate 5-dehydrogenase:Glycerol-3-phosphate dehydrogenase:Uridine kinase:UDP-N-acetylmuramyl tripeptide synthase:Collagenase and related proteases:Predicted GTPases:ABC-type spermidine/putrescine transport system, permease component I:ABC-type spermidine/putrescine transport system, permease component II:Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog):ATP-dependent protease HslVU (ClpYQ), ATPase subunit:Membrane protein involved in the export of O-antigen and teichoic acid:Cell shape-determining protein:Protein containing tetrapyrrole methyltransferase domain and MazG-like (predicted pyrophosphatase) domain:Predicted membrane protein:Pleiotropic transcriptional repressor:Site-specific recombinase XerD:ATP-dependent protease HslVU (ClpYQ), peptidase subunit:Amino acid transport and metabolism:Nucleotide transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:Replication, recombination and repair:Cell wall/membrane/envelope biogenesis:Posttranslational modification, protein turnover, chaperones:Pyrimidine metabolism:Lysine biosynthesis:Phenylalanine tyrosine and tryptophan biosynthesis:Peptidoglycan biosynthesis:Glycerophospholipid metabolism:Metabolic pathways:Biosynthesis of secondary metabolites:ABC transporters:General function prediction only:Function unknown:small_GTP:udk:hslU:mazG:aroE:murE:recomb_XerC:codY_Gpos:spore_yabP:shape_MreD:ATP_dep_HslV:Cellular processes and signaling:Metabolism:Poorly characterized:Degradation of proteins, peptides, and glycopeptides:Protein folding and stabilization:Protein fate:DNA replication, recombination, and repair:DNA metabolism:DNA interactions:Regulatory functions:Salvage of nucleosides and nucleotides:Purines, pyrimidines, nucleosides, and nucleotides:Metabolism:Metabolism:Global:Membrane Transport:Environmental Information Processing:Glycan Biosynthesis and Metabolism:Amino Acid Metabolism:Nucleotide Metabolism:Cellular processes:Lipid Metabolism:Sporulation and germination:Unknown function:General:Amino acid biosynthesis:Aromatic amino acid family:Cell envelope:Biosynthesis and degradation of murein sacculus and peptidoglycan:Information storage and processing" 50 "DNA repair exonuclease:Glycine/D-amino acid oxidases (deaminating):Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain:Flagellar biosynthesis/type III secretory pathway ATPase:Oligoendopeptidase F:Flagellar hook-associated protein:Flagellin and related hook-associated proteins:Flagellar capping protein:Flagellar motor switch protein:Flagellar basal body rod protein:Flagellar hook-basal body protein:Flagellar hook protein FlgE:Flagellar biosynthesis/type III secretory pathway lipoprotein:Flagellar basal body protein:Flagellar motor switch protein:Signal transduction histidine kinase regulating citrate/malate metabolism:Beta- N-acetylglucosaminidase:Amino acid transport and metabolism:Carbohydrate transport and metabolism:Transcription:Replication, recombination and repair:Cell motility:Phenylalanine metabolism:Nitrogen metabolism:Two-component system:Bacterial chemotaxis:Flagellar assembly:Signal transduction mechanisms:fliG:fliI_yscN:FlgC:FlgB:flgK_ends:flagell_flgL:FlgEFG_subfam:Intracellular trafficking, secretion, and vesicular transport:Metabolism:Energy Metabolism:Amino Acid Metabolism:Environmental Information Processing:Signal Transduction:Cellular Processes:Cell Motility:Energy metabolism:ATP-proton motive force interconversion:Cellular processes:Chemotaxis and motility:Information storage and processing:Cellular processes and signaling:Metabolism" 51 "Energy production and conversion:Glutamate-1-semialdehyde aminotransferase:Xaa-Pro aminopeptidase:Putative translation factor (SUA5):Delta-aminolevulinic acid dehydratase:5-enolpyruvylshikimate-3-phosphate synthase:Porphobilinogen deaminase:Pyridoxine biosynthesis enzyme:Predicted glutamine amidotransferase involved in pyridoxine biosynthesis:Glutamyl-tRNA reductase:ABC-type transport system involved in cytochrome c biogenesis, permease component:3-dehydroquinate dehydratase II:Pyruvate carboxylase:Uroporphyrinogen-III synthase:Predicted CoA-binding protein:Amino acid transport and metabolism:Coenzyme transport and metabolism:Translation, ribosomal structure and biogenesis:Posttranslational modification, protein turnover, chaperones:Citrate cycle (TCA cycle):Phenylalanine tyrosine and tryptophan biosynthesis:Pyruvate metabolism:Vitamin B6 metabolism:Porphyrin and chlorophyll metabolism:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:General function prediction only:TIGR00057:hemC:TIGR00343:hemL:hemA:aroQ:pyruv_carbox:aroA:PLP_synth_Pdx2:Amino acid biosynthesis:General:Unknown function:Glycolysis/gluconeogenesis:Energy metabolism:Metabolism:Metabolism:Global:Metabolism of Cofactors and Vitamins:Amino Acid Metabolism:Biosynthesis of cofactors, prosthetic groups, and carriers:Carbohydrate Metabolism:Heme, porphyrin, and cobalamin:Pyridoxine:Information storage and processing:Cellular processes and signaling:Metabolism:Poorly characterized:Aromatic amino acid family" 52 "Hydrogenase maturation factor:NTP pyrophosphohydrolases including oxidative damage repair enzymes:Transcriptional regulator:Erythromycin esterase homolog:Uncharacterized vancomycin resistance protein:Predicted oxidoreductase related to nitroreductase:Transcription:Replication, recombination and repair:Posttranslational modification, protein turnover, chaperones:Two-component system:Flagellar assembly:General function prediction only:hypF:2A0309:Defense mechanisms:Cellular processes and signaling:Signal Transduction:Cellular Processes:Cell Motility:Protein fate:Protein modification and repair:Transport and binding proteins:Amino acids, peptides and amines:Information storage and processing:Environmental Information Processing:Poorly characterized" 53 "Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases:ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component:ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component:ABC-type metal ion transport system, ATPase component:ABC-type dipeptide/oligopeptide/nickel transport systems, permease components:ABC-type metal ion transport system, periplasmic component/surface antigen:Uncharacterized conserved protein, contains double-stranded beta-helix domain:Ribulose 1,5-bisphosphate carboxylase, large subunit:ABC-type metal ion transport system, permease component:Uncharacterized conserved protein, possibly involved in methylthioadenosine recycling:Amino acid transport and metabolism:Carbohydrate transport and metabolism:Inorganic ion transport and metabolism:Cysteine and methionine metabolism:Metabolic pathways:ABC transporters:Function unknown:HAD-SF-IB:oligo_HPY:salvage_mtnB:salvage_mtnW:Enzymes of unknown specificity:Amino Acid Metabolism:Environmental Information Processing:Membrane Transport:Global:Metabolism:Central intermediary metabolism:Sulfur metabolism:Transport and binding proteins:Amino acids, peptides and amines:Unknown function:Metabolism:Amino acid biosynthesis:Aspartate family:Metabolism:Poorly characterized" 54 "Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2:SAM-dependent methyltransferases:Amino acid transporters:ABC-type Fe3+-siderophore transport system, permease component:ABC-type Fe3+-hydroxamate transport system, periplasmic component:Uncharacterized membrane protein:UDP-N-acetylglucosamine enolpyruvyl transferase:ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components:ABC-type multidrug transport system, ATPase component:Alpha-galactosidases/6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases:Predicted membrane protein:D-alanyl-D-alanine carboxypeptidase:Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains:Predicted Zn-dependent protease:Amino acid transport and metabolism:Carbohydrate transport and metabolism:Coenzyme transport and metabolism:Transcription:Cell wall/membrane/envelope biogenesis:Posttranslational modification, protein turnover, chaperones:Inorganic ion transport and metabolism:Glycolysis / Gluconeogenesis:Bisphenol degradation:Amino sugar and nucleotide sugar metabolism:Peptidoglycan biosynthesis:Polycyclic aromatic hydrocarbon degradation:Aminobenzoate degradation:Limonene and pinene degradation:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:ABC transporters:Sulfur relay system:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:Function unknown:Signal transduction mechanisms:murA:xxxLxxG_by_4:exospor_lead:Defense mechanisms:Metabolism:Global:Membrane Transport:Environmental Information Processing:Metabolism:Folding Sorting and Degradation:Genetic Information Processing:Xenobiotics Biodegradation and Metabolism:Metabolism of Terpenoids and Polyketides:Glycan Biosynthesis and Metabolism:Poorly characterized:Carbohydrate Metabolism:Metabolism:Cellular processes and signaling:Information storage and processing:Biosynthesis and degradation of murein sacculus and peptidoglycan:Cell envelope:Sporulation and germination:Cellular processes" 55 "Nicotinate-nucleotide pyrophosphorylase:Quinolinate synthase:Signal transduction histidine kinase:Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain:Predicted DNA modification methylase:Uncharacterized protein conserved in bacteria:Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain:SAM-dependent methyltransferases related to tRNA (uracil-5-)-methyltransferase:Uncharacterized protein conserved in bacteria:Predicted ATPase:ABC-type oligopeptide transport system, periplasmic component:Amino acid transport and metabolism:Coenzyme transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:Replication, recombination and repair:Valine leucine and isoleucine degradation:Histidine metabolism:Tyrosine metabolism:Selenocompound metabolism:Polycyclic aromatic hydrocarbon degradation:Glyoxylate and dicarboxylate metabolism:Propanoate metabolism:Carbon fixation pathways in prokaryotes:Nicotinate and nicotinamide metabolism:Metabolic pathways:Microbial metabolism in diverse environments:ABC transporters:Two-component system:General function prediction only:Function unknown:Signal transduction mechanisms:nadC:rumA:nadA:Cellular processes and signaling:Carbohydrate Metabolism:Energy Metabolism:Amino Acid Metabolism:Metabolism of Other Amino Acids:Metabolism of Cofactors and Vitamins:Xenobiotics Biodegradation and Metabolism:Environmental Information Processing:Membrane Transport:Signal Transduction:Global:Metabolism:Protein synthesis:tRNA and rRNA base modification:Biosynthesis of cofactors, prosthetic groups, and carriers:Pyridine nucleotides:Information storage and processing:Metabolism:Metabolism:Poorly characterized" 56 "Acetyltransferase (isoleucine patch superfamily):ATPase components of ABC transporters with duplicated ATPase domains:Transcriptional regulator:Signal transduction histidine kinase:HD superfamily phosphohydrolases:ABC-type multidrug transport system, ATPase and permease components:ABC-type enterochelin transport system, ATPase component:ABC-type enterochelin transport system, permease component:ABC-type enterochelin transport system, permease component:ABC-type enterochelin transport system, periplasmic component:Transcription:Inorganic ion transport and metabolism:ABC transporters:General function prediction only:Signal transduction mechanisms:Defense mechanisms:Metabolism:Cellular processes and signaling:Information storage and processing:Environmental Information Processing:Membrane Transport:Poorly characterized" 57 "Mg2+ and Co2+ transporters:Cystathionine beta-lyases/cystathionine gamma-synthases:Predicted permease:Signal transduction histidine kinase:Putative intracellular protease/amidase:Catalase:Polyphosphate kinase:DNA-directed RNA polymerase specialized sigma subunit:Methylase of chemotaxis methyl-accepting proteins:Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor):Anti-sigma regulatory factor (Ser/Thr protein kinase):Bacterioferritin (cytochrome b1):Serine phosphatase RsbU, regulator of sigma subunit:Amino acid transport and metabolism:Transcription:Cell motility:Inorganic ion transport and metabolism:Oxidative phosphorylation:Cysteine and methionine metabolism:Tryptophan metabolism:Selenocompound metabolism:Methane metabolism:Metabolic pathways:Microbial metabolism in diverse environments:Two-component system:Bacterial chemotaxis:RNA degradation:RNA polymerase:General function prediction only:Signal transduction mechanisms:ant_ant_sig:met_gam_lyase:PfpI:rsbW_low_gc:spore_V_AD:spore_ger_x_C:sigma70-ECF:poly_P_kin:Metabolism:Poorly characterized:Metabolism:Global:Cell Motility:Cellular Processes:Metabolism:Signal Transduction:Environmental Information Processing:Folding Sorting and Degradation:Transcription:Genetic Information Processing:Metabolism of Other Amino Acids:Amino Acid Metabolism:Energy Metabolism:Central intermediary metabolism:Phosphorus compounds:Energy metabolism:Amino acids and amines:Regulatory functions:Protein interactions:Protein fate:Degradation of proteins, peptides, and glycopeptides:Cellular processes:Sporulation and germination:Information storage and processing:Cellular processes and signaling" 58 "1-acyl-sn-glycerol-3-phosphate acyltransferase:Acyl carrier protein:3-oxoacyl-(acyl-carrier-protein) synthase:(acyl-carrier-protein) S-malonyltransferase:3-oxoacyl-[acyl-carrier-protein] synthase III:Fatty acid/phospholipid biosynthesis enzyme:Biotin carboxyl carrier protein:dsRNA-specific ribonuclease:Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily):Enoyl-[acyl-carrier-protein] reductase (NADH):Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases):Uncharacterized proteins of the AP superfamily:Uncharacterized protein, possibly involved in aromatic compounds catabolism:Permeases of the major facilitator superfamily:Fatty acid desaturase:Lipid transport and metabolism:Transcription:Fatty acid biosynthesis:Bisphenol degradation:Glycerolipid metabolism:Glycerophospholipid metabolism:Pyruvate metabolism:Aminobenzoate degradation:Propanoate metabolism:Biosynthesis of unsaturated fatty acids:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:Two-component system:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:fabD:plsX:acyl_carrier:BCCP:fabH:3oxo_ACP_reduc:RNaseIII:fabF:Poorly characterized:Metabolism:Information storage and processing:RNA processing:Transcription:Biosynthesis:Fatty acid and phospholipid metabolism:Metabolism:Metabolism:Global:Signal Transduction:Environmental Information Processing:Xenobiotics Biodegradation and Metabolism:Lipid Metabolism:Carbohydrate Metabolism" 59 "Energy production and conversion:Serine-pyruvate aminotransferase/archaeal aspartate aminotransferase:NADPH:quinone reductase and related Zn-dependent oxidoreductases:Putative intracellular protease/amidase:UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase:Periplasmic protease:Acyl-CoA hydrolase:Glycerate kinase:Transcriptional regulator, contains sigma factor-related N-terminal domain:Uncharacterized conserved protein:Uncharacterized protein conserved in bacteria:Uncharacterized conserved protein:Predicted permease, DMT superfamily:Amino acid transport and metabolism:Carbohydrate transport and metabolism:Lipid transport and metabolism:Transcription:Cell wall/membrane/envelope biogenesis:Glycine serine and threonine metabolism:Phosphonate and phosphinate metabolism:Peptidoglycan biosynthesis:Glycerolipid metabolism:Glyoxylate and dicarboxylate metabolism:Methane metabolism:Metabolic pathways:Microbial metabolism in diverse environments:General function prediction only:Function unknown:TIGR00045:prc:beta_rpt_yvtn:transamin_PhnW:spore_VI_D:Poorly characterized:Metabolism:Global:Glycan Biosynthesis and Metabolism:Metabolism of Other Amino Acids:Amino Acid Metabolism:Metabolism:Lipid Metabolism:Energy Metabolism:Central intermediary metabolism:Carbohydrate Metabolism:Phosphorus compounds:Energy metabolism:Other:Protein fate:Protein modification and repair:Cellular processes:Sporulation and germination:Information storage and processing:Cellular processes and signaling:Metabolism" 60 "Zn-dependent hydrolases, including glyoxylases:Predicted membrane-associated Zn-dependent proteases 1:Diacylglycerol kinase:Predicted amidophosphoribosyltransferases:Phosphomannomutase:ABC-type multidrug transport system, ATPase component:ABC-type multidrug transport system, ATPase and permease components:Transcriptional regulator:DNA uptake protein and related DNA-binding proteins:Predicted transcriptional regulators:Predicted extracellular nuclease:Signal transduction histidine kinase:Carbohydrate transport and metabolism:Transcription:Replication, recombination and repair:Cell wall/membrane/envelope biogenesis:Fructose and mannose metabolism:Amino sugar and nucleotide sugar metabolism:Glycerolipid metabolism:Glycerophospholipid metabolism:Metabolic pathways:Biosynthesis of secondary metabolites:General function prediction only:Signal transduction mechanisms:TIGR00426:LPXTG_anchor:spore_IV_B:Defense mechanisms:Sporulation and germination:DNA transformation:Cellular processes:Metabolism:Metabolism:Global:Lipid Metabolism:Poorly characterized:Carbohydrate Metabolism:Metabolism:Cellular processes and signaling:Information storage and processing:Other:Cell envelope" 61 "Membrane proteins related to metalloendopeptidases:Cell wall/membrane/envelope biogenesis:spore_III_AE:SASP_H:Sporulation and germination:Cellular processes:Cellular processes and signaling" 62 "Fructose-2,6-bisphosphatase:Predicted hydrolases of the HAD superfamily:Adenine-specific DNA methylase:DNA polymerase III, epsilon subunit and related 3'-5' exonucleases:Uncharacterized protein conserved in bacteria:Permeases:Predicted hydrolase (metallo-beta-lactamase superfamily):Uncharacterized Zn-ribbon-containing protein involved in phosphonate metabolism:Carbohydrate transport and metabolism:Replication, recombination and repair:Inorganic ion transport and metabolism:Glycolysis / Gluconeogenesis:Phosphonate and phosphinate metabolism:Methane metabolism:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:General function prediction only:Function unknown:Cof-subfamily:TIGR00282:phnA:spore_ypjB:Unknown function:Carbohydrate Metabolism:Energy Metabolism:Metabolism of Other Amino Acids:Global:Metabolism:Cellular processes:Sporulation and germination:Metabolism:Enzymes of unknown specificity:General:Information storage and processing:Metabolism:Poorly characterized" 63 "Energy production and conversion:Preprotein translocase subunit SecY:Peptide methionine sulfoxide reductase:Integral membrane protein possibly involved in chromosome condensation:Folylpolyglutamate synthase:Glycosidases:Acetyltransferases:IMP dehydrogenase/GMP reductase:NADPH:quinone reductase and related Zn-dependent oxidoreductases:Predicted transcriptional regulators:Signal transduction histidine kinase:FOG: Ankyrin repeat:Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain:ABC-type antimicrobial peptide transport system, ATPase component:Ribose/xylose/arabinose/galactoside ABC-type transport systems, permease components:Uncharacterized protein conserved in bacteria:DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog:D-alanyl-D-alanine carboxypeptidase:Uncharacterized protein conserved in bacteria:Predicted transcriptional regulator:Predicted membrane protein:ABC-type oligopeptide transport system, periplasmic component:Membrane protein involved in cytochrome C biogenesis:Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain:Cell cycle control, cell division, chromosome partitioning:Amino acid transport and metabolism:Nucleotide transport and metabolism:Carbohydrate transport and metabolism:Coenzyme transport and metabolism:Transcription:Cell wall/membrane/envelope biogenesis:Posttranslational modification, protein turnover, chaperones:Purine metabolism:Peptidoglycan biosynthesis:Folate biosynthesis:Metabolic pathways:Biosynthesis of secondary metabolites:ABC transporters:RNA polymerase:Protein export:Bacterial secretion system:General function prediction only:Function unknown:Signal transduction mechanisms:sensory_box:msrA:crcB:3a0501s007:IMP_dehydrog:folC:sigma70-ECF:Intracellular trafficking, secretion, and vesicular transport:Defense mechanisms:Cellular processes and signaling:Nucleotide Metabolism:Glycan Biosynthesis and Metabolism:Metabolism of Cofactors and Vitamins:Genetic Information Processing:Transcription:Folding Sorting and Degradation:Environmental Information Processing:Membrane Transport:Global:Metabolism:Purines, pyrimidines, nucleosides, and nucleotides:Purine ribonucleotide biosynthesis:Regulatory functions:Small molecule interactions:Protein fate:Protein and peptide secretion and trafficking:Cellular processes:Adaptations to atypical conditions:Unknown function:General:Biosynthesis of cofactors, prosthetic groups, and carriers:Folic acid:Information storage and processing:Metabolism:Metabolism:Poorly characterized" 64 "Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain:Phosphatidylserine synthase:Uncharacterized conserved protein:Uncharacterized host factor I protein:Predicted membrane protein:Uncharacterized protein conserved in bacteria:Predicted membrane protein:Uncharacterized protein conserved in bacteria:Lipid transport and metabolism:Transcription:Glycine serine and threonine metabolism:Glycerophospholipid metabolism:Metabolic pathways:RNA degradation:General function prediction only:Function unknown:Signal transduction mechanisms:pssA:integ_TIGR01906:Hfq:Other:Lipid Metabolism:Amino Acid Metabolism:Genetic Information Processing:Folding Sorting and Degradation:Global:Metabolism:Fatty acid and phospholipid metabolism:Biosynthesis:Regulatory functions:Metabolism:Information storage and processing:Cellular processes and signaling:Metabolism:Poorly characterized" 65 "ABC-type phosphate transport system, periplasmic component:ABC-type sugar transport system, permease component:Glycosyltransferase:ATPase components of ABC transporters with duplicated ATPase domains:Putative GTPases (G3E family):ABC-type phosphate transport system, permease component:ABC-type phosphate transport system, permease component:Membrane-associated phospholipid phosphatase:Phosphate uptake regulator:ABC-type phosphate transport system, ATPase component:ABC-type sugar transport systems, permease components:ABC-type Fe3+ transport system, permease component:ABC-type sugar transport system, periplasmic component:Alkaline phosphatase:ABC-type Fe3+ transport system, periplasmic component:Glycerol-3-phosphate responsive antiterminator (mRNA-binding):Predicted flavoprotein involved in K+ transport:ABC-type sugar transport systems, ATPase components:ABC-type spermidine/putrescine transport systems, ATPase components:Amino acid transport and metabolism:Carbohydrate transport and metabolism:Lipid transport and metabolism:Transcription:Cell wall/membrane/envelope biogenesis:Inorganic ion transport and metabolism:Aminobenzoate degradation:Folate biosynthesis:Metabolic pathways:Microbial metabolism in diverse environments:ABC transporters:Two-component system:General function prediction only:3a0107s01c2:3a0107s02c:phoU_full:ptsS_2:phosphate_pstC:phnS2:PhnU2:PhnT2:Poorly characterized:Metabolism:Cellular processes and signaling:Information storage and processing:Anions:Amino acids, peptides and amines:Transport and binding proteins:Metabolism:Metabolism:Global:Signal Transduction:Membrane Transport:Environmental Information Processing:Xenobiotics Biodegradation and Metabolism:Metabolism of Cofactors and Vitamins" 66 "Ribonucleotide reductase, beta subunit:Ribonucleotide reductase, alpha subunit:Queuine/archaeosine tRNA-ribosyltransferase:ATPase components of ABC transporters with duplicated ATPase domains:Na+-driven multidrug efflux pump:Arylsulfatase regulator (Fe-S oxidoreductase):UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase:16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases:Predicted membrane protein:Membrane protein involved in the export of O-antigen and teichoic acid:Nucleotide transport and metabolism:Translation, ribosomal structure and biogenesis:Cell wall/membrane/envelope biogenesis:Purine metabolism:Pyrimidine metabolism:Peptidoglycan biosynthesis:Metabolic pathways:General function prediction only:Function unknown:TIGR00093:Q_tRNA_tgt:matE:murG:NrdE_NrdA:Defense mechanisms:Poorly characterized:Cell envelope:Other:Transport and binding proteins:tRNA and rRNA base modification:Protein synthesis:2'-Deoxyribonucleotide metabolism:Purines, pyrimidines, nucleosides, and nucleotides:Metabolism:Metabolism:Global:Glycan Biosynthesis and Metabolism:Biosynthesis and degradation of murein sacculus and peptidoglycan:Nucleotide Metabolism:Information storage and processing:Cellular processes and signaling:Metabolism" 67 "Energy production and conversion:Chloride channel protein EriC:Xanthosine triphosphate pyrophosphatase:Glycosyltransferase:Translation initiation factor 2 (IF-2; GTPase):CDP-diglyceride synthetase:Glutathionylspermidine synthase:Diacylglycerol kinase:N-acetylmuramoyl-L-alanine amidase:Predicted amidophosphoribosyltransferases:Choline-glycine betaine transporter:Uncharacterized protein conserved in bacteria:Uncharacterized protein conserved in bacteria:Na+/H+ antiporter:Sugar phosphate permease:Arabinose efflux permease:Predicted membrane protein:Superfamily II DNA/RNA helicase required for DNA uptake (late competence protein):Uncharacterized protein conserved in bacteria:Amino acid transport and metabolism:Nucleotide transport and metabolism:Carbohydrate transport and metabolism:Lipid transport and metabolism:Translation, ribosomal structure and biogenesis:Replication, recombination and repair:Cell wall/membrane/envelope biogenesis:Inorganic ion transport and metabolism:Fructose and mannose metabolism:Purine metabolism:Glutathione metabolism:Glycerolipid metabolism:Glycerophospholipid metabolism:Methane metabolism:Thiamine metabolism:Metabolic pathways:General function prediction only:Function unknown:TIGR00042:small_GTP:bcct:antiport_nhaC:Metabolism:Carbohydrate Metabolism:Energy Metabolism:Lipid Metabolism:Nucleotide Metabolism:Metabolism of Other Amino Acids:Metabolism of Cofactors and Vitamins:Global:Metabolism:DNA metabolism:DNA replication, recombination, and repair:Transport and binding proteins:Cations and iron carrying compounds:Other:Unknown function:General:Information storage and processing:Cellular processes and signaling:Metabolism:Poorly characterized" 68 "Energy production and conversion:Glycosyltransferase:Acetyltransferases:ATPase components of ABC transporters with duplicated ATPase domains:Predicted phosphatases:Adenylate kinase and related kinases:Predicted phosphohydrolases:Uncharacterized protein conserved in bacteria:Predicted acetamidase/formamidase:Uncharacterized protein conserved in bacteria:Uncharacterized protein conserved in bacteria:Nucleotide transport and metabolism:Cell wall/membrane/envelope biogenesis:Fructose and mannose metabolism:Arginine and proline metabolism:Phenylalanine metabolism:Tryptophan metabolism:Cyanoamino acid metabolism:Aminobenzoate degradation:Glyoxylate and dicarboxylate metabolism:Styrene degradation:Metabolic pathways:Microbial metabolism in diverse environments:General function prediction only:Function unknown:HAD-SF-IIIA:Enzymes of unknown specificity:Carbohydrate Metabolism:Amino Acid Metabolism:Metabolism of Other Amino Acids:Xenobiotics Biodegradation and Metabolism:Global:Metabolism:Unknown function:Metabolism:Cellular processes and signaling:Metabolism:Poorly characterized" 69 "Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis:Glycosyltransferase:Biotin carboxylase:Nucleoside-diphosphate-sugar epimerases:Superfamily II DNA and RNA helicases:Predicted glycosyltransferases:ATP-dependent protease HslVU (ClpYQ), ATPase subunit:Deoxynucleoside kinases:Sugar transferases involved in lipopolysaccharide synthesis:Pleiotropic transcriptional repressor:Site-specific recombinase XerD:ATP-dependent protease HslVU (ClpYQ), peptidase subunit:Nucleotide transport and metabolism:Carbohydrate transport and metabolism:Lipid transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:Replication, recombination and repair:Cell wall/membrane/envelope biogenesis:Posttranslational modification, protein turnover, chaperones:Fructose and mannose metabolism:Purine metabolism:Metabolic pathways:General function prediction only:hslU:recomb_XerC:codY_Gpos:ATP_dep_HslV:Poorly characterized:Carbohydrate Metabolism:Nucleotide Metabolism:Global:Metabolism:Regulatory functions:DNA interactions:DNA metabolism:DNA replication, recombination, and repair:Protein fate:Protein folding and stabilization:Degradation of proteins, peptides, and glycopeptides:Information storage and processing:Cellular processes and signaling:Metabolism:Metabolism" 70 "Energy production and conversion:Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit:Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase:Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component, and related enzymes:Preprotein translocase subunit SecA (ATPase, RNA helicase):Phosphoglyceromutase:Preprotein translocase subunit YidC:Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit:Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes:Cold shock proteins:Transcriptional regulators:Phosphotransferase system, HPr-related proteins:Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases:Transcriptional regulator, contains sigma factor-related N-terminal domain:Predicted membrane protein:Carbohydrate transport and metabolism:Transcription:Glycolysis / Gluconeogenesis:Citrate cycle (TCA cycle):Glycine serine and threonine metabolism:Valine leucine and isoleucine degradation:Valine leucine and isoleucine biosynthesis:Pyruvate metabolism:Butanoate metabolism:Methane metabolism:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:Protein export:Bacterial secretion system:Function unknown:secA:PTS_HPr_family:pgm_bpd_ind:lipoamide_DH:GAPDH-I:PDH_E1_alph_x:yidC_oxa1_cterm:Intracellular trafficking, secretion, and vesicular transport:Metabolism:Poorly characterized:Information storage and processing:PTS:Signal transduction:Protein and peptide secretion and trafficking:Protein fate:Pyruvate dehydrogenase:Glycolysis/gluconeogenesis:Metabolism:Global:Energy metabolism:Membrane Transport:Environmental Information Processing:Metabolism:Folding Sorting and Degradation:Genetic Information Processing:Amino Acid Metabolism:Energy Metabolism:Cellular processes and signaling:Carbohydrate Metabolism" 71 "Pseudouridine synthase:FAD synthase:Cytidine deaminase:Guanosine polyphosphate pyrophosphohydrolases/synthetases:Uncharacterized protein conserved in bacteria:Ribosome-binding factor A:Ribosomal protein HS6-type (S12/L30/L7a):Uncharacterized protein conserved in bacteria:Predicted nucleic-acid-binding protein implicated in transcription termination:Nucleotide transport and metabolism:Coenzyme transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:Purine metabolism:Pyrimidine metabolism:Riboflavin metabolism:Metabolic pathways:Function unknown:Signal transduction mechanisms:rbfA:ribF:TruB:spoT_relA:cyt_deam_tetra:Information storage and processing:Cellular processes and signaling:Metabolism:Poorly characterized:Cellular processes:tRNA and rRNA base modification:Protein synthesis:RNA processing:Transcription:Salvage of nucleosides and nucleotides:Purines, pyrimidines, nucleosides, and nucleotides:Metabolism:Metabolism:Global:Metabolism of Cofactors and Vitamins:Adaptations to atypical conditions:Nucleotide Metabolism:Biosynthesis of cofactors, prosthetic groups, and carriers:Riboflavin, FMN, and FAD" 72 "Energy production and conversion:Phosphoribosylformylglycinamidine (FGAM) synthase, glutamine amidotransferase domain:Predicted Co/Zn/Cd cation transporters:Mg-dependent DNase:Peptide methionine sulfoxide reductase:Protoheme ferro-lyase (ferrochelatase):Predicted phosphatases:Transcriptional regulator:Uncharacterized homolog of gamma-carboxymuconolactone decarboxylase subunit:NADPH:quinone reductase and related Zn-dependent oxidoreductases:Alanine racemase:Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases):Amidases related to nicotinamidase:Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase:Acetyltransferases, including N-acetylases of ribosomal proteins:Phosphoribosylformylglycinamidine (FGAM) synthase, PurS component:Predicted metal-dependent hydrolase:Transcriptional regulator/sugar kinase:ABC-type metal ion transport system, permease component:Membrane transporters of cations and cationic drugs:FOG: EAL domain:Dihydroxyacetone kinase:1-aminocyclopropane-1-carboxylate deaminase:Uncharacterized conserved protein:Amino acid transport and metabolism:Nucleotide transport and metabolism:Carbohydrate transport and metabolism:Coenzyme transport and metabolism:Lipid transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:Replication, recombination and repair:Cell wall/membrane/envelope biogenesis:Posttranslational modification, protein turnover, chaperones:Inorganic ion transport and metabolism:Glycolysis / Gluconeogenesis:Galactose metabolism:Fatty acid metabolism:Purine metabolism:Cysteine and methionine metabolism:Tyrosine metabolism:D-Alanine metabolism:Starch and sucrose metabolism:Amino sugar and nucleotide sugar metabolism:Streptomycin biosynthesis:Glycerolipid metabolism:Chloroalkane and chloroalkene degradation:Naphthalene degradation:Glyoxylate and dicarboxylate metabolism:Methane metabolism:Porphyrin and chlorophyll metabolism:Biosynthesis of siderophore group nonribosomal peptides:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:ABC transporters:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:Function unknown:Signal transduction mechanisms:TIGR00010:YbaK_EbsC:hemH:TIGR00147:TIGR00302:TIGR00357:alr:ROK_glcA_fam:ACC_deam_rel:CDF:HAD-SF-IA-v1:FGAM_synth_I:dhaK1b:oxido_YhdH:Metabolism of Other Amino Acids:Amino Acid Metabolism:Nucleotide Metabolism:Lipid Metabolism:Energy Metabolism:Carbohydrate Metabolism:Purines, pyrimidines, nucleosides, and nucleotides:Purine ribonucleotide biosynthesis:Transport and binding proteins:Cations and iron carrying compounds:Cellular processes:Adaptations to atypical conditions:Unknown function:Enzymes of unknown specificity:General:Biosynthesis of cofactors, prosthetic groups, and carriers:Heme, porphyrin, and cobalamin:Cell envelope:Biosynthesis and degradation of murein sacculus and peptidoglycan:Information storage and processing:Cellular processes and signaling:Metabolism:Poorly characterized:Metabolism:Global:Membrane Transport:Environmental Information Processing:Metabolism:Xenobiotics Biodegradation and Metabolism:Biosynthesis of Other Secondary Metabolites:Metabolism of Terpenoids and Polyketides:Metabolism of Cofactors and Vitamins" 73 "Energy production and conversion:Prephenate dehydratase:Fructose-2,6-bisphosphatase:Aspartate/tyrosine/aromatic aminotransferase:3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratases:NAD-dependent aldehyde dehydrogenases:Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases):NADH dehydrogenase, FAD-containing subunit:Beta-lactamase class C and other penicillin binding proteins:Acyl dehydratase:Poly(3-hydroxyalkanoate) synthetase:Uncharacterized protein conserved in bacteria:Uncharacterized conserved protein:Short-chain alcohol dehydrogenase of unknown specificity:Pantothenate kinase, acetyl-CoA regulated:Protein involved in biosynthesis of mitomycin antibiotics/polyketide fumonisin:Amino acid transport and metabolism:Carbohydrate transport and metabolism:Coenzyme transport and metabolism:Lipid transport and metabolism:Glycolysis / Gluconeogenesis:Fatty acid biosynthesis:Oxidative phosphorylation:Alanine aspartate and glutamate metabolism:Arginine and proline metabolism:Phenylalanine tyrosine and tryptophan biosynthesis:Glyoxylate and dicarboxylate metabolism:Butanoate metabolism:Methane metabolism:Pantothenate and CoA biosynthesis:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:Function unknown:panK_eukar:D1pyr5carbox2:AcAcCoA_reduct:PHA_synth_III_C:phaP_Bmeg:phaR_Bmeg:Defense mechanisms:Pantothenate and coenzyme A:Biosynthesis of cofactors, prosthetic groups, and carriers:Biosynthesis:Fatty acid and phospholipid metabolism:Amino acids and amines:Energy metabolism:Cellular processes and signaling:Metabolism:Poorly characterized:Metabolism:Metabolism:Global:Metabolism of Cofactors and Vitamins:Amino Acid Metabolism:Lipid Metabolism:Energy Metabolism:Carbohydrate Metabolism" 74 "Energy production and conversion:Ribosomal protein L33:Phosphotransacetylase:Molybdenum cofactor biosynthesis enzyme:Glycine cleavage system H protein (lipoate-binding):Putative GTPases (G3E family):Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases:Predicted transcriptional regulators:Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family:Molybdopterin-guanine dinucleotide biosynthesis protein A:3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratases:Bacterial nucleoid DNA-binding protein:Predicted transcriptional regulators:Uncharacterized protein conserved in bacteria:Predicted membrane protein:Regulators of stationary/sporulation gene expression:Phosphotransferase system IIA components:Uncharacterized conserved protein:Amino acid transport and metabolism:Carbohydrate transport and metabolism:Coenzyme transport and metabolism:Lipid transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:Replication, recombination and repair:Posttranslational modification, protein turnover, chaperones:Glycolysis / Gluconeogenesis:Fatty acid biosynthesis:Lysine biosynthesis:Taurine and hypotaurine metabolism:Starch and sucrose metabolism:Amino sugar and nucleotide sugar metabolism:Pyruvate metabolism:Propanoate metabolism:Methane metabolism:Carbon fixation pathways in prokaryotes:Metabolic pathways:Microbial metabolism in diverse environments:Two-component system:Phosphotransferase system (PTS):Ribosome:Sulfur relay system:General function prediction only:Function unknown:gcvH:moaC:pta:PTBA:rpmG_bact:lp_hng_hel_AbrB:fabZ:dipeptidaselike:Information storage and processing:Carbohydrate Metabolism:Energy Metabolism:Lipid Metabolism:Amino Acid Metabolism:Metabolism of Other Amino Acids:Genetic Information Processing:Translation:Folding Sorting and Degradation:Environmental Information Processing:Membrane Transport:Signal Transduction:Global:Metabolism:Energy metabolism:Amino acids and amines:Fermentation:Fatty acid and phospholipid metabolism:Biosynthesis:Regulatory functions:DNA interactions:Protein synthesis:Ribosomal proteins: synthesis and modification:Biosynthesis of cofactors, prosthetic groups, and carriers:Molybdopterin:Signal transduction:PTS:Metabolism:Cellular processes and signaling:Metabolism:Poorly characterized" 75 "Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), A subunit:Glycosyltransferase:Superfamily II DNA and RNA helicases:Transcriptional regulator:ABC-type multidrug transport system, ATPase component:Choline-glycine betaine transporter:Uncharacterized conserved protein:Predicted transcriptional regulators:Teichoic acid biosynthesis proteins:Membrane protein involved in the export of O-antigen and teichoic acid:GTPases:Predicted membrane protein:Uncharacterized protein conserved in bacteria:Translation, ribosomal structure and biogenesis:Transcription:Replication, recombination and repair:Cell wall/membrane/envelope biogenesis:Fructose and mannose metabolism:General function prediction only:Function unknown:wecG_tagA_cpsF:bcct:gyrA:GTP_HflX:Defense mechanisms:DNA replication, recombination, and repair:DNA metabolism:Information storage and processing:Carbohydrate Metabolism:Cellular processes and signaling:Poorly characterized:Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides:Metabolism:Cell envelope:General:Unknown function:Other:Transport and binding proteins" 76 "Energy production and conversion:Uncharacterized conserved protein:Nucleoside-diphosphate-sugar epimerases:Pseudouridylate synthases, 23S RNA-specific:Transcriptional regulator:NADPH:quinone reductase and related Zn-dependent oxidoreductases:Permeases of the drug/metabolite transporter (DMT) superfamily:N-acetylmuramoyl-L-alanine amidase:ABC-type multidrug transport system, ATPase component:Acyl carrier protein phosphodiesterase:Squalene cyclase:Predicted transcriptional regulators:Na+/H+ antiporter:Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain:Uncharacterized protein conserved in bacteria:Arabinose efflux permease:DNA gyrase inhibitor:UV damage repair endonuclease:Amino acid transport and metabolism:Carbohydrate transport and metabolism:Lipid transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:Replication, recombination and repair:Cell wall/membrane/envelope biogenesis:Biosynthesis of secondary metabolites:ABC transporters:Two-component system:General function prediction only:Function unknown:Signal transduction mechanisms:rluA_subfam:uvde:squalene_cyclas:spore_dpaA:spore_cwlD:Defense mechanisms:Environmental Information Processing:Poorly characterized:Metabolism:Cellular processes and signaling:Information storage and processing:Sporulation and germination:Cellular processes:tRNA and rRNA base modification:Protein synthesis:DNA replication, recombination, and repair:DNA metabolism:Metabolism:Global:Signal Transduction:Membrane Transport" 77 "Riboflavin synthase beta-chain:3,4-dihydroxy-2-butanone 4-phosphate synthase:NAD synthase:Riboflavin synthase alpha chain:Uncharacterized conserved protein:ABC-type Fe3+-siderophore transport system, permease component:ABC-type Fe3+-hydroxamate transport system, periplasmic component:ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components:Acyl-CoA hydrolase:Pyrimidine reductase, riboflavin biosynthesis:Phosphopantetheinyl transferase:Arylamine N-acetyltransferase:Di- and tripeptidases:Uncharacterized enzyme involved in biosynthesis of extracellular polysaccharides:Uncharacterized protein conserved in bacteria:Uncharacterized protein conserved in bacteria:Cell surface protein:Amino acid transport and metabolism:Coenzyme transport and metabolism:Lipid transport and metabolism:Cell wall/membrane/envelope biogenesis:Inorganic ion transport and metabolism:Riboflavin metabolism:Nicotinate and nicotinamide metabolism:Nitrogen metabolism:Metabolic pathways:ABC transporters:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:Function unknown:lumazine-synth:ribE:ribD_Cterm:ribA:nadE:peptidase-T:srtB_target:sortase_srtB:IsdE:Cellular processes and signaling:Energy Metabolism:Metabolism of Cofactors and Vitamins:Environmental Information Processing:Membrane Transport:Global:Metabolism:Protein fate:Protein and peptide secretion and trafficking:Degradation of proteins, peptides, and glycopeptides:Biosynthesis of cofactors, prosthetic groups, and carriers:Riboflavin, FMN, and FAD:Pyridine nucleotides:Metabolism:Metabolism:Poorly characterized" 78 "Aspartate oxidase:Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily):UDP-glucose 4-epimerase:Coenzyme transport and metabolism:Cell wall/membrane/envelope biogenesis:Alanine aspartate and glutamate metabolism:Nicotinate and nicotinamide metabolism:Metabolic pathways:General function prediction only:nadB:Pyridine nucleotides:Amino Acid Metabolism:Metabolism of Cofactors and Vitamins:Global:Metabolism:Biosynthesis of cofactors, prosthetic groups, and carriers:Metabolism:Cellular processes and signaling:Metabolism:Poorly characterized" 79 "Energy production and conversion:Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), B subunit:Queuine/archaeosine tRNA-ribosyltransferase:Glycosyltransferases involved in cell wall biogenesis:Na+-driven multidrug efflux pump:Single-stranded DNA-specific exonuclease:Nitroreductase:S-adenosylmethionine:tRNA-ribosyltransferase-isomerase (queuine synthetase):Predicted permease:Na+/melibiose symporter and related transporters:Holliday junction resolvasome, helicase subunit:Predicted membrane protein:Membrane domain of membrane-anchored glycerophosphoryl diester phosphodiesterase:Carbohydrate transport and metabolism:Translation, ribosomal structure and biogenesis:Replication, recombination and repair:Cell wall/membrane/envelope biogenesis:Glycerophospholipid metabolism:Base excision repair:Mismatch repair:Homologous recombination:General function prediction only:Function unknown:queA:Q_tRNA_tgt:ruvB:recJ:efflux_EmrB:matE:gyrB:Defense mechanisms:Transport and binding proteins:tRNA and rRNA base modification:Protein synthesis:DNA replication, recombination, and repair:DNA metabolism:Metabolism:Replication and Repair:Genetic Information Processing:Poorly characterized:Lipid Metabolism:Metabolism:Cellular processes and signaling:Information storage and processing:Other" 80 "Predicted transcriptional regulators:Membrane transporters of cations and cationic drugs:Predicted sugar phosphate isomerase:Arabinose efflux permease:Uncharacterized protein conserved in bacteria:Uncharacterized conserved protein:Carbohydrate transport and metabolism:Transcription:Inorganic ion transport and metabolism:Amino sugar and nucleotide sugar metabolism:General function prediction only:Function unknown:TIGR00274:2A0309:spore_ger_x_C:Metabolism:Carbohydrate Metabolism:Transport and binding proteins:Amino acids, peptides and amines:Cellular processes:Sporulation and germination:Cell envelope:Biosynthesis and degradation of murein sacculus and peptidoglycan:Information storage and processing:Metabolism:Poorly characterized" 81 "Lipoate-protein ligase A:Fructose-2,6-bisphosphatase:UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N-acetylglucosamine-1-phosphate transferase:ATPase involved in DNA replication initiation:Rhodanese-related sulfurtransferase:UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase:Recombinational DNA repair ATPase (RecF pathway):Predicted metal-dependent membrane protease:Mn-dependent transcriptional regulator:Uncharacterized homolog of PSP1:Predicted transcriptional regulator:Uncharacterized conserved protein:DNA polymerase III, gamma/tau subunits:Uncharacterized conserved protein:Uncharacterized protein conserved in bacteria:Uncharacterized protein conserved in bacteria:Carbohydrate transport and metabolism:Coenzyme transport and metabolism:Transcription:Replication, recombination and repair:Cell wall/membrane/envelope biogenesis:Inorganic ion transport and metabolism:Glycolysis / Gluconeogenesis:Purine metabolism:Pyrimidine metabolism:Glycerolipid metabolism:Methane metabolism:Lipoic acid metabolism:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:Two-component system:DNA replication:Mismatch repair:Homologous recombination:General function prediction only:Function unknown:DnaA:recf:holB:YaaA_near_RecF:Genetic Information Processing:Metabolism of Cofactors and Vitamins:Nucleotide Metabolism:Lipid Metabolism:Energy Metabolism:DNA metabolism:Carbohydrate Metabolism:DNA replication, recombination, and repair:Information storage and processing:Cellular processes and signaling:Metabolism:Poorly characterized:Metabolism:Metabolism:Global:Signal Transduction:Environmental Information Processing:Replication and Repair" 82 "Ribosomal protein L14:Ribosomal protein L5:Ribosomal protein S8:Ribosomal protein L6P/L9E:Ribosomal protein S5:Ribosomal protein S13:Ribosomal protein S11:Ribosomal protein S17:Ribosomal protein L16/L10E:Ribosomal protein L24:Ribosomal protein S14:Ribosomal protein L15:DNA-directed RNA polymerase, alpha subunit/40 kD subunit:Ribosomal protein L29:Ribosomal protein L18:Translation initiation factor 1 (IF-1):Adenylate kinase and related kinases:Ribosomal protein L30/L7E:Nucleotide transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:Purine metabolism:Pyrimidine metabolism:Metabolic pathways:Biosynthesis of secondary metabolites:Ribosome:RNA polymerase:infA:L29:L18_bact:rpsE_bact:rplN_bact:rplO_bact:rplX_bact:rplP_bact:rpmD_bact:adk:rpoA:bact_S13:bact_S11:S17_bact:L6_bact:Metabolism:Nucleotide Metabolism:Genetic Information Processing:Transcription:Translation:Global:Metabolism:Purines, pyrimidines, nucleosides, and nucleotides:Nucleotide and nucleoside interconversions:Transcription:DNA-dependent RNA polymerase:Protein synthesis:Ribosomal proteins: synthesis and modification:Translation factors:Information storage and processing:Metabolism" 83 "Energy production and conversion:Tryptophan synthase beta chain:Indole-3-glycerol phosphate synthase:Phosphoribosylanthranilate isomerase:Anthranilate/para-aminobenzoate synthases component I:Tryptophan synthase alpha chain:3-dehydroquinate synthetase:Anthranilate/para-aminobenzoate synthases component II:Anthranilate phosphoribosyltransferase:Rieske Fe-S protein:Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases):ABC-type multidrug transport system, ATPase component:Predicted transcriptional regulators:Flagellar motor switch protein:Uncharacterized conserved protein:Pyrrolidone-carboxylate peptidase (N-terminal pyroglutamyl peptidase):Predicted membrane protein:Amino acid transport and metabolism:Coenzyme transport and metabolism:Lipid transport and metabolism:Transcription:Cell motility:Posttranslational modification, protein turnover, chaperones:Oxidative phosphorylation:Glycine serine and threonine metabolism:Histidine metabolism:Tyrosine metabolism:Phenylalanine tyrosine and tryptophan biosynthesis:Selenocompound metabolism:Polycyclic aromatic hydrocarbon degradation:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:Bacterial chemotaxis:Flagellar assembly:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:Function unknown:trpA:trpB:pyro_pdase:trpE_most:trpG_papA:TIGR00702:trpD:aroB:antibiot_sagB:thiopep_ocin:Defense mechanisms:Information storage and processing:Aromatic amino acid family:Amino acid biosynthesis:Conserved:Hypothetical proteins:Toxin production and resistance:Cellular processes:Degradation of proteins, peptides, and glycopeptides:Protein fate:Metabolism:Metabolism:Global:Cell Motility:Cellular Processes:Xenobiotics Biodegradation and Metabolism:Metabolism of Other Amino Acids:Amino Acid Metabolism:Energy Metabolism:Poorly characterized:Metabolism:Cellular processes and signaling" 84 "Energy production and conversion:Nucleoside-diphosphate-sugar epimerases:NADPH:quinone reductase and related Zn-dependent oxidoreductases:Permeases of the drug/metabolite transporter (DMT) superfamily:Membrane proteins related to metalloendopeptidases:Catalase:Predicted nucleotide kinase:Retron-type reverse transcriptase:Inhibitor of the KinA pathway to sporulation, predicted exonuclease:Amino acid transport and metabolism:Nucleotide transport and metabolism:Carbohydrate transport and metabolism:Replication, recombination and repair:Cell wall/membrane/envelope biogenesis:Inorganic ion transport and metabolism:Tryptophan metabolism:Amino sugar and nucleotide sugar metabolism:Methane metabolism:Metabolic pathways:Microbial metabolism in diverse environments:General function prediction only:put_anti_recept:CDP_4_6_dhtase:Cellular processes and signaling:Carbohydrate Metabolism:Energy Metabolism:Amino Acid Metabolism:Global:Metabolism:Mobile and extrachromosomal element functions:Prophage functions:Cell envelope:Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides:Information storage and processing:Metabolism:Metabolism:Poorly characterized" 85 "Energy production and conversion:tRNA delta(2)-isopentenylpyrophosphate transferase:Transcriptional regulator:Glycine/D-amino acid oxidases (deaminating):Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains):Ribose/xylose/arabinose/galactoside ABC-type transport systems, permease components:Predicted transcriptional regulators:Acetyltransferases, including N-acetylases of ribosomal proteins:Glycosyl transferases, related to UDP-glucuronosyltransferase:Periplasmic molybdate-binding protein/domain:Uncharacterized host factor I protein:Site-specific recombinases, DNA invertase Pin homologs:Membrane transporters of cations and cationic drugs:Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain:FOG: EAL domain:Predicted membrane protein:Predicted transcriptional regulator:Uncharacterized conserved protein:Uncharacterized protein conserved in bacteria:Site-specific recombinase XerD:Uncharacterized conserved protein:Amino acid transport and metabolism:Carbohydrate transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:Replication, recombination and repair:Cell wall/membrane/envelope biogenesis:Inorganic ion transport and metabolism:Metabolic pathways:Biosynthesis of secondary metabolites:ABC transporters:Two-component system:Flagellar assembly:RNA degradation:General function prediction only:Function unknown:Signal transduction mechanisms:miaA:MGT:excise:Hfq:spore_ger_x_C:Poorly characterized:Folding Sorting and Degradation:Environmental Information Processing:Membrane Transport:Signal Transduction:Cellular Processes:Cell Motility:Global:Metabolism:Regulatory functions:Other:Protein synthesis:tRNA and rRNA base modification:Cellular processes:Toxin production and resistance:Sporulation and germination:Unknown function:General:Information storage and processing:Cellular processes and signaling:Metabolism:Genetic Information Processing" 86 "Energy production and conversion:ABC-type phosphate transport system, periplasmic component:Glycosyltransferase:Uncharacterized NAD(FAD)-dependent dehydrogenases:ABC-type phosphate transport system, permease component:ABC-type phosphate transport system, permease component:NADPH:quinone reductase and related Zn-dependent oxidoreductases:Membrane-associated phospholipid phosphatase:Predicted permeases:ABC-type phosphate transport system, ATPase component:Acetyltransferases, including N-acetylases of ribosomal proteins:Predicted transcriptional regulators:Alkaline phosphatase:Predicted flavoprotein involved in K+ transport:Permeases of the major facilitator superfamily:Sugar phosphate permease:Carbohydrate transport and metabolism:Lipid transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:Cell wall/membrane/envelope biogenesis:Inorganic ion transport and metabolism:Tyrosine metabolism:Benzoate degradation:Naphthalene degradation:Aminobenzoate degradation:Ethylbenzene degradation:Folate biosynthesis:Limonene and pinene degradation:Metabolic pathways:Microbial metabolism in diverse environments:ABC transporters:Two-component system:General function prediction only:efflux_Bcr_CflA:3a0107s01c2:3a0107s02c:ptsS_2:phosphate_pstC:CoA_CoA_reduc:Detoxification:Cellular processes:Anions:Transport and binding proteins:Metabolism:Metabolism:Global:Signal Transduction:Membrane Transport:Environmental Information Processing:Xenobiotics Biodegradation and Metabolism:Metabolism of Terpenoids and Polyketides:Metabolism of Cofactors and Vitamins:Poorly characterized:Amino Acid Metabolism:Metabolism:Cellular processes and signaling:Information storage and processing" 87 "Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase:Carbohydrate transport and metabolism:Glycolysis / Gluconeogenesis:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:GAPDH-I:Metabolism:Energy metabolism:Glycolysis/gluconeogenesis:Metabolism:Global:Metabolism:Carbohydrate Metabolism" 88 "1-acyl-sn-glycerol-3-phosphate acyltransferase:Kef-type K+ transport systems, membrane components:Putative regulatory, ligand-binding protein related to C-terminal domains of K+ channels:NTP pyrophosphohydrolases including oxidative damage repair enzymes:Uncharacterized membrane-associated protein:DNA polymerase sliding clamp subunit (PCNA homolog):Small-conductance mechanosensitive channel:Predicted transcriptional regulators:Hemolysins and related proteins containing CBS domains:Predicted membrane protein, hemolysin III homolog:Transcriptional regulators:DNA polymerase III, gamma/tau subunits:Arabinose efflux permease:Predicted membrane protein:Carbohydrate transport and metabolism:Lipid transport and metabolism:Transcription:Replication, recombination and repair:Cell wall/membrane/envelope biogenesis:Inorganic ion transport and metabolism:Purine metabolism:Pyrimidine metabolism:Glycerolipid metabolism:Glycerophospholipid metabolism:Metabolic pathways:DNA replication:Mismatch repair:Homologous recombination:General function prediction only:Function unknown:AGP_acyltrn:dnan:2a37:hlyIII:dnaX_nterm:Information storage and processing:Lipid Metabolism:Nucleotide Metabolism:Genetic Information Processing:Replication and Repair:Global:Metabolism:Fatty acid and phospholipid metabolism:Biosynthesis:DNA metabolism:DNA replication, recombination, and repair:Transport and binding proteins:Cations and iron carrying compounds:Metabolism:Cellular processes and signaling:Metabolism:Poorly characterized" 89 "Predicted transcriptional regulators:Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases):Predicted HD superfamily hydrolase:Lipid transport and metabolism:Transcription:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:Information storage and processing:Poorly characterized:Metabolism" 90 "Energy production and conversion:Malate/lactate dehydrogenases:Ribosomal protein L17:Predicted rRNA methylase (SpoU class):Acetyltransferases:Rhodanese-related sulfurtransferase:ABC-type Fe3+-hydroxamate transport system, periplasmic component:Hypoxanthine-guanine phosphoribosyltransferase:Putative intracellular protease/amidase:Nitroreductase:Galactose mutarotase and related enzymes:SH3 domain protein:Predicted DNA alkylation repair enzyme:Nucleotide transport and metabolism:Carbohydrate transport and metabolism:Translation, ribosomal structure and biogenesis:Replication, recombination and repair:Inorganic ion transport and metabolism:Glycolysis / Gluconeogenesis:Purine metabolism:Cysteine and methionine metabolism:Tyrosine metabolism:Benzoate degradation:Pyruvate metabolism:Naphthalene degradation:Aminobenzoate degradation:Propanoate metabolism:Ethylbenzene degradation:Limonene and pinene degradation:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:ABC transporters:Ribosome:General function prediction only:Signal transduction mechanisms:L17:rRNA_methyl_2:HGPRTase:L-LDH-NAD:integ_memb_HG:Membrane Transport:Environmental Information Processing:Translation:Genetic Information Processing:Metabolism:Xenobiotics Biodegradation and Metabolism:Metabolism of Terpenoids and Polyketides:Amino Acid Metabolism:Nucleotide Metabolism:Carbohydrate Metabolism:Energy metabolism:Glycolysis/gluconeogenesis:Purines, pyrimidines, nucleosides, and nucleotides:Salvage of nucleosides and nucleotides:Protein synthesis:Ribosomal proteins: synthesis and modification:tRNA and rRNA base modification:Unknown function:General:Information storage and processing:Cellular processes and signaling:Metabolism:Poorly characterized:Metabolism:Global" 91 "Zn-dependent hydrolases, including glyoxylases:Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily):Predicted dithiol-disulfide isomerase involved in polyketide biosynthesis:Putative NADH-flavin reductase:Predicted protein-disulfide isomerase:Predicted oxidoreductase related to nitroreductase:Ketosteroid isomerase-related protein:Uncharacterized protein conserved in bacteria:Posttranslational modification, protein turnover, chaperones:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:Function unknown:Poorly characterized:Metabolism:Cellular processes and signaling" 92 "Energy production and conversion:Adenylosuccinate lyase:Phosphoribosylaminoimidazole carboxylase (NCAIR synthetase):Phosphoribosylcarboxyaminoimidazole (NCAIR) mutase:Cytosine deaminase and related metal-dependent hydrolases:Na+-driven multidrug efflux pump:Signal recognition particle GTPase:Glycerol uptake facilitator and related permeases (Major Intrinsic Protein Family):ABC-type metal ion transport system, periplasmic component/surface adhesin:Superfamily I DNA and RNA helicases and helicase subunits:Chromosome segregation ATPases:Rad3-related DNA helicases:Na+/H+-dicarboxylate symporters:Nucleoside permease:Predicted membrane protein:16S RNA G1207 methylase RsmC:Arabinose efflux permease:Cell cycle control, cell division, chromosome partitioning:Nucleotide transport and metabolism:Carbohydrate transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:Replication, recombination and repair:Inorganic ion transport and metabolism:Purine metabolism:Alanine aspartate and glutamate metabolism:Metabolic pathways:Biosynthesis of secondary metabolites:ABC transporters:Protein export:Bacterial secretion system:General function prediction only:Function unknown:ftsY:matE:nupC:purB:purK:purE:SMC_prok_B:DNA_bind_RsfA:Intracellular trafficking, secretion, and vesicular transport:Defense mechanisms:Cellular processes:Nucleotide Metabolism:Amino Acid Metabolism:Genetic Information Processing:Folding Sorting and Degradation:Environmental Information Processing:Membrane Transport:Global:Metabolism:Purines, pyrimidines, nucleosides, and nucleotides:Purine ribonucleotide biosynthesis:DNA metabolism:Chromosome-associated proteins:Protein fate:Protein and peptide secretion and trafficking:Transport and binding proteins:Nucleosides, purines and pyrimidines:Other:Metabolism:Sporulation and germination:Information storage and processing:Cellular processes and signaling:Metabolism:Poorly characterized" 93 "Energy production and conversion:Glutamine phosphoribosylpyrophosphate amidotransferase:Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis:Aldo/keto reductases, related to diketogulonate reductase:dTDP-glucose pyrophosphorylase:Acetyltransferases, including N-acetylases of ribosomal proteins:Ni,Fe-hydrogenase III component G:Nucleotide transport and metabolism:Translation, ribosomal structure and biogenesis:Cell wall/membrane/envelope biogenesis:Oxidative phosphorylation:Purine metabolism:Alanine aspartate and glutamate metabolism:Streptomycin biosynthesis:Polyketide sugar unit biosynthesis:Metabolic pathways:Biosynthesis of secondary metabolites:General function prediction only:purF:NuoC_fam:Electron transport:Energy Metabolism:Nucleotide Metabolism:Amino Acid Metabolism:Metabolism of Terpenoids and Polyketides:Biosynthesis of Other Secondary Metabolites:Global:Metabolism:Energy metabolism:Metabolism:Purines, pyrimidines, nucleosides, and nucleotides:Purine ribonucleotide biosynthesis:Information storage and processing:Cellular processes and signaling:Metabolism:Poorly characterized" 94 "Arginyl-tRNA synthetase:Predicted N6-adenine-specific DNA methylase:tRNA and rRNA cytosine-C5-methylases:Methionyl-tRNA formyltransferase:Thiamine biosynthesis ATP pyrophosphatase:2-methylthioadenine synthetase:Cell division protein FtsI/penicillin-binding protein 2:Cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes:Predicted GTPases:NAD(FAD)-utilizing enzyme possibly involved in translation:Predicted RNA-binding protein containing KH domain, possibly ribosomal protein:Amino acid transport and metabolism:Coenzyme transport and metabolism:Translation, ribosomal structure and biogenesis:Replication, recombination and repair:Cell wall/membrane/envelope biogenesis:One carbon pool by folate:Thiamine metabolism:Aminoacyl-tRNA biosynthesis:Metabolic pathways:Sulfur relay system:General function prediction only:TIGR00089:gid_trmFO:RNA_bind_YhbY:TIGR00342:argS:fmt:rsmB:GTPase_YqeH:Metabolism:Metabolism of Cofactors and Vitamins:Genetic Information Processing:Translation:Folding Sorting and Degradation:Global:Metabolism:Protein synthesis:Other:tRNA aminoacylation:tRNA and rRNA base modification:Unknown function:General:Information storage and processing:Cellular processes and signaling:Metabolism:Poorly characterized" 95 "Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II:DhnA-type fructose-1,6-bisphosphate aldolase and related enzymes:Carbohydrate transport and metabolism:Lipid transport and metabolism:Fatty acid metabolism:Benzoate degradation:Bisphenol degradation:Naphthalene degradation:Butanoate metabolism:Limonene and pinene degradation:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:Secondary metabolites biosynthesis, transport and catabolism:phge_HK97_gp10:spore_III_AG:M6dom_TIGR03296:exospor_lead:Mobile and extrachromosomal element functions:Prophage functions:Metabolism:Xenobiotics Biodegradation and Metabolism:Metabolism of Terpenoids and Polyketides:Lipid Metabolism:Metabolism:Carbohydrate Metabolism:Global:Metabolism:Cellular processes:Sporulation and germination" 96 "Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase]:Predicted epimerase, PhzC/PhzF homolog:Transcriptional regulator:Permeases of the drug/metabolite transporter (DMT) superfamily:Predicted phosphohydrolases:Nucleoside permease:Uncharacterized conserved protein:Lysophospholipase:Beta-lactamase class A:Predicted permeases:SH3 domain protein:Amino acid transport and metabolism:Nucleotide transport and metabolism:Carbohydrate transport and metabolism:Coenzyme transport and metabolism:Lipid transport and metabolism:Transcription:Penicillin and cephalosporin biosynthesis:Pyruvate metabolism:Metabolic pathways:Biosynthesis of secondary metabolites:Two-component system:General function prediction only:Function unknown:Signal transduction mechanisms:PduO_Nterm:PhzF_family:2A0309:antibiot_sagB:Defense mechanisms:Cellular processes and signaling:Carbohydrate Metabolism:Biosynthesis of Other Secondary Metabolites:Environmental Information Processing:Signal Transduction:Global:Metabolism:Transport and binding proteins:Amino acids, peptides and amines:Cellular processes:Toxin production and resistance:Biosynthesis of cofactors, prosthetic groups, and carriers:Heme, porphyrin, and cobalamin:Information storage and processing:Metabolism:Metabolism:Poorly characterized" 97 "Kef-type K+ transport systems, membrane components:Transcriptional regulator:Predicted transcriptional regulators:Fucose permease:Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain:FOG: CheY-like receiver:Uncharacterized protein conserved in bacteria:Uncharacterized host factor I protein:Beta-lactamase class A:Predicted transcriptional regulator containing CBS domains:ABC-type oligopeptide transport system, periplasmic component:Glycopeptide antibiotics resistance protein:Amino acid transport and metabolism:Carbohydrate transport and metabolism:Transcription:Inorganic ion transport and metabolism:ABC transporters:Two-component system:Bacterial chemotaxis:RNA degradation:General function prediction only:Function unknown:Signal transduction mechanisms:efflux_EmrB:Hfq:Defense mechanisms:Regulatory functions:Genetic Information Processing:Cell Motility:Cellular Processes:Signal Transduction:Membrane Transport:Environmental Information Processing:Metabolism:Folding Sorting and Degradation:Poorly characterized:Cellular processes and signaling:Information storage and processing:Other:Transport and binding proteins:Other" 98 "Energy production and conversion:Glucan phosphorylase:Mg-dependent DNase:Acetyltransferase (isoleucine patch superfamily):ATPases involved in chromosome partitioning:Parvulin-like peptidyl-prolyl isomerase:Galactose-1-phosphate uridylyltransferase:Transcriptional regulators, similar to M. xanthus CarD:Amidases related to nicotinamidase:DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog:Phage shock protein A (IM30), suppresses sigma54-dependent transcription:Lysophospholipase:Predicted ring-cleavage extradiol dioxygenase:Uncharacterized protein involved in tellurite resistance:Predicted O-methyltransferase:Uncharacterized protein conserved in bacteria:Cell cycle control, cell division, chromosome partitioning:Carbohydrate transport and metabolism:Lipid transport and metabolism:Transcription:Replication, recombination and repair:Posttranslational modification, protein turnover, chaperones:Inorganic ion transport and metabolism:Phenylalanine metabolism:Starch and sucrose metabolism:Glycerophospholipid metabolism:Biosynthesis of siderophore group nonribosomal peptides:Metabolic pathways:Biosynthesis of secondary metabolites:Two-component system:RNA polymerase:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:Function unknown:Signal transduction mechanisms:P_ylase:sigma70-ECF:Metabolism:Metabolism:Global:Poorly characterized:Signal Transduction:Environmental Information Processing:Metabolism:Transcription:Genetic Information Processing:Cellular processes and signaling:Metabolism of Terpenoids and Polyketides:Information storage and processing:Amino Acid Metabolism:Biosynthesis and degradation of polysaccharides:Lipid Metabolism:Energy metabolism:Carbohydrate Metabolism" 99 "Predicted sugar kinase:DNA primase (bacterial type):ATP-dependent Lon protease, bacterial type:Exoribonuclease R:Phosphatidylglycerophosphate synthase:Bacterial cell division membrane protein:S-adenosylmethionine:tRNA-ribosyltransferase-isomerase (queuine synthetase):Predicted nucleotide-utilizing enzyme related to molybdopterin-biosynthesis enzyme MoeA:Uncharacterized protein conserved in bacteria:Holliday junction resolvasome, helicase subunit:ABC-type spermidine/putrescine transport systems, ATPase components:Cell cycle control, cell division, chromosome partitioning:Amino acid transport and metabolism:Carbohydrate transport and metabolism:Lipid transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:Replication, recombination and repair:Posttranslational modification, protein turnover, chaperones:Glycerophospholipid metabolism:Nicotinate and nicotinamide metabolism:Metabolic pathways:ABC transporters:RNA degradation:DNA replication:Homologous recombination:General function prediction only:Function unknown:queA:molyb_syn:3_prime_RNase:pgsA:ruvB:lon:dnaG:Metabolism:Lipid Metabolism:Metabolism of Cofactors and Vitamins:Genetic Information Processing:Folding Sorting and Degradation:Replication and Repair:Environmental Information Processing:Membrane Transport:Global:Metabolism:Fatty acid and phospholipid metabolism:Biosynthesis:DNA metabolism:DNA replication, recombination, and repair:Transcription:Degradation of RNA:Protein synthesis:tRNA and rRNA base modification:Protein fate:Degradation of proteins, peptides, and glycopeptides:Information storage and processing:Cellular processes and signaling:Metabolism:Poorly characterized" 100 "Energy production and conversion:Aspartyl/asparaginyl-tRNA synthetases:Malate/lactate dehydrogenases:Predicted Co/Zn/Cd cation transporters:Predicted membrane protein:FOG: CBS domain:Predicted hydrolases of the HAD superfamily:Predicted transcriptional regulators:Arginine repressor:Acetyltransferases, including N-acetylases of ribosomal proteins:Regulators of stationary/sporulation gene expression:Transcriptional regulators:Sugar phosphate permease:Predicted transcriptional regulator:Predicted secreted protein:Protein involved in sex pheromone biosynthesis:Carbohydrate transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:Inorganic ion transport and metabolism:Glycolysis / Gluconeogenesis:Cysteine and methionine metabolism:Pyruvate metabolism:Propanoate metabolism:Aminoacyl-tRNA biosynthesis:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:ABC transporters:General function prediction only:Function unknown:Cof-subfamily:asnS:2A0104:CDF:lp_hng_hel_AbrB:argR_whole:L-LDH-NAD:Metabolism:Carbohydrate Metabolism:Amino Acid Metabolism:Genetic Information Processing:Translation:Environmental Information Processing:Membrane Transport:Global:Metabolism:Energy metabolism:Glycolysis/gluconeogenesis:Regulatory functions:DNA interactions:Protein synthesis:tRNA aminoacylation:Transport and binding proteins:Carbohydrates, organic alcohols, and acids:Cations and iron carrying compounds:Unknown function:Enzymes of unknown specificity:Information storage and processing:Metabolism:Poorly characterized" 101 "Energy production and conversion:Predicted phosphatases:ABC-type sulfate transport system, permease component:DNA-directed RNA polymerase specialized sigma subunit:Siroheme synthase (precorrin-2 oxidase/ferrochelatase domain):Aspartate racemase:Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases:Uncharacterized protein conserved in bacteria:Lyzozyme M1 (1,4-beta-N-acetylmuramidase):Coenzyme transport and metabolism:Transcription:Cell wall/membrane/envelope biogenesis:Posttranslational modification, protein turnover, chaperones:Alanine aspartate and glutamate metabolism:Glyoxylate and dicarboxylate metabolism:Porphyrin and chlorophyll metabolism:Metabolic pathways:Biosynthesis of secondary metabolites:ABC transporters:RNA polymerase:General function prediction only:Function unknown:asp_race:3a0106s02:cysG_Nterm:HAD-SF-IIIA:spore_sigmaE:spore_II_P:alk_sulf_monoox:Enzymes of unknown specificity:Biosynthesis of cofactors, prosthetic groups, and carriers:Heme, porphyrin, and cobalamin:Information storage and processing:Cellular processes and signaling:Metabolism:Poorly characterized:Metabolism:Global:Metabolism:Membrane Transport:Environmental Information Processing:Transcription:Genetic Information Processing:Metabolism of Cofactors and Vitamins:Amino Acid Metabolism:Carbohydrate Metabolism:Central intermediary metabolism:Sulfur metabolism:Energy metabolism:Amino acids and amines:Transport and binding proteins:Anions:Cellular processes:Sporulation and germination:Unknown function" 102 "Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily):Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain:Methyl-accepting chemotaxis protein:Inosine-uridine nucleoside N-ribohydrolase:Serine phosphatase RsbU, regulator of sigma subunit:Predicted membrane protein:Uncharacterized protein conserved in bacteria:Nucleotide transport and metabolism:Transcription:Cell motility:Purine metabolism:Nicotinate and nicotinamide metabolism:Metabolic pathways:Two-component system:Bacterial chemotaxis:General function prediction only:Function unknown:Signal transduction mechanisms:spore_V_AC:spore_V_AE:spore_V_AD:spore_II_E:Cellular processes:Nucleotide Metabolism:Metabolism of Cofactors and Vitamins:Environmental Information Processing:Signal Transduction:Cellular Processes:Cell Motility:Global:Metabolism:Metabolism:Sporulation and germination:Information storage and processing:Cellular processes and signaling:Metabolism:Poorly characterized" 103 "Membrane protease subunits, stomatin/prohibitin homologs:Putative GTPases (G3E family):Na+-driven multidrug efflux pump:Predicted hydrolases of the HAD superfamily:Glutaredoxin and related proteins:Ribose 5-phosphate isomerase RpiB:Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific:Uncharacterized conserved protein:Cellulase M and related proteins:Predicted transcriptional regulators:Tetrahydrodipicolinate N-succinyltransferase:Putative NADPH-quinone reductase (modulator of drug activity B):Predicted metal-dependent enzyme:Uncharacterized protein conserved in bacteria:Amino acid transport and metabolism:Carbohydrate transport and metabolism:Transcription:Posttranslational modification, protein turnover, chaperones:Pentose phosphate pathway:Lysine biosynthesis:Amino sugar and nucleotide sugar metabolism:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:Phosphotransferase system (PTS):General function prediction only:Function unknown:Cof-subfamily:rpiB_lacA_lacB:matE:EIIB_glc:TIGR01440:GlrX_YruB:DapD_Ac:Defense mechanisms:Signal transduction:Carbohydrate Metabolism:Amino Acid Metabolism:Environmental Information Processing:Membrane Transport:Global:Metabolism:Transport and binding proteins:Other:Hypothetical proteins:Conserved:Unknown function:Enzymes of unknown specificity:Metabolism:PTS:Information storage and processing:Cellular processes and signaling:Metabolism:Poorly characterized" 104 "Energy production and conversion:Hydrogenase maturation factor:Acetyltransferase (isoleucine patch superfamily):Trk-type K+ transport systems, membrane components:DNA repair exonuclease:Kef-type K+ transport systems, membrane components:NADPH:quinone reductase and related Zn-dependent oxidoreductases:ABC-type Fe3+-hydroxamate transport system, periplasmic component:ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component:ABC-type multidrug transport system, ATPase and permease components:Ribose/xylose/arabinose/galactoside ABC-type transport systems, permease components:Inosine-uridine nucleoside N-ribohydrolase:Zinc metalloprotease (elastase):Signal transduction histidine kinase:Predicted phage phi-C31 gp36 major capsid-like protein:Spore coat assembly protein:Amino acid transport and metabolism:Nucleotide transport and metabolism:Carbohydrate transport and metabolism:Replication, recombination and repair:Cell wall/membrane/envelope biogenesis:Posttranslational modification, protein turnover, chaperones:Inorganic ion transport and metabolism:Purine metabolism:Nicotinate and nicotinamide metabolism:Metabolic pathways:ABC transporters:General function prediction only:Signal transduction mechanisms:hypF:2a37:LPXTG_anchor:Defense mechanisms:Metabolism:Poorly characterized:Metabolism:Cellular processes and signaling:Information storage and processing:Other:Cell envelope:Cations and iron carrying compounds:Transport and binding proteins:Protein modification and repair:Protein fate:Metabolism:Global:Membrane Transport:Environmental Information Processing:Metabolism of Cofactors and Vitamins:Nucleotide Metabolism" 105 "Transaldolase:Uncharacterized conserved protein:Protein-tyrosine-phosphatase:Cytosine deaminase and related metal-dependent hydrolases:Predicted Zn-dependent peptidases:Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases:Predicted permease:Uracil DNA glycosylase:Predicted permeases:5'-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases:Protease subunit of ATP-dependent Clp proteases:Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases):Sugar (pentulose and hexulose) kinases:ABC-type proline/glycine betaine transport systems, ATPase components:Predicted phosphohydrolases:Nicotinic acid phosphoribosyltransferase:DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog:Periplasmic glycine betaine/choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein):Uncharacterized protein, possibly involved in aromatic compounds catabolism:Xanthine/uracil permeases:H+/gluconate symporter and related permeases:Lysophospholipase L1 and related esterases:Amino acid transport and metabolism:Nucleotide transport and metabolism:Carbohydrate transport and metabolism:Coenzyme transport and metabolism:Lipid transport and metabolism:Transcription:Replication, recombination and repair:Cell wall/membrane/envelope biogenesis:Posttranslational modification, protein turnover, chaperones:Pentose phosphate pathway:Fatty acid biosynthesis:Purine metabolism:Pyrimidine metabolism:Arginine and proline metabolism:Nicotinate and nicotinamide metabolism:Biosynthesis of unsaturated fatty acids:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:ABC transporters:RNA polymerase:Base excision repair:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:Function unknown:Signal transduction mechanisms:unchar_dom_1:clpP:ung:gntP:fsa_talC_mipB:proV:gntK_FGGY:NAPRTase_put:DapE-ArgE:sigma70-ECF:Intracellular trafficking, secretion, and vesicular transport:Cellular processes and signaling:Information storage and processing:Pyridine nucleotides:Biosynthesis of cofactors, prosthetic groups, and carriers:Carbohydrates, organic alcohols, and acids:Amino acids, peptides and amines:Transport and binding proteins:Degradation of proteins, peptides, and glycopeptides:Protein fate:DNA replication, recombination, and repair:DNA metabolism:Sugars:Pentose phosphate pathway:Energy metabolism:Metabolism:Metabolism:Global:Membrane Transport:Environmental Information Processing:Replication and Repair:Transcription:Genetic Information Processing:Metabolism of Cofactors and Vitamins:Amino Acid Metabolism:Nucleotide Metabolism:Lipid Metabolism:Carbohydrate Metabolism:Poorly characterized:Metabolism" 106 "Energy production and conversion:Thioredoxin reductase:Glycine/D-amino acid oxidases (deaminating):Predicted oxidoreductases (related to aryl-alcohol dehydrogenases):MoxR-like ATPases:Membrane protein TerC, possibly involved in tellurium resistance:Thermophilic glucose-6-phosphate isomerase and related metalloenzymes:Arabinose efflux permease:Predicted membrane protein:Proline racemase:Amino acid transport and metabolism:Carbohydrate transport and metabolism:Posttranslational modification, protein turnover, chaperones:Inorganic ion transport and metabolism:Glycine serine and threonine metabolism:Arginine and proline metabolism:Glyoxylate and dicarboxylate metabolism:Metabolic pathways:General function prediction only:Function unknown:bicupin_oxalic:R_switched_YjbE:TIGR03943:Carbohydrate Metabolism:Poorly characterized:Metabolism:Cellular processes and signaling:Metabolism:Global:Amino Acid Metabolism:Metabolism" 107 "Energy production and conversion:Uncharacterized conserved protein:Leucyl aminopeptidase:Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase:Thioredoxin reductase:NTP pyrophosphohydrolases including oxidative damage repair enzymes:Thiol-disulfide isomerase and thioredoxins:Ribosomal protein S1:Predicted hydrolases of the HAD superfamily:Uncharacterized conserved protein:Ketopantoate reductase:Peroxiredoxin:Di- and tripeptidases:Leucyl aminopeptidase (aminopeptidase T):Amino acid transport and metabolism:Coenzyme transport and metabolism:Translation, ribosomal structure and biogenesis:Replication, recombination and repair:Posttranslational modification, protein turnover, chaperones:Purine metabolism:Pyrimidine metabolism:Glutathione metabolism:Vitamin B6 metabolism:Pantothenate and CoA biosynthesis:Metabolic pathways:Biosynthesis of secondary metabolites:Ribosome:General function prediction only:Function unknown:HMP-P_kinase:Cof-subfamily:TIGR00106:apbA_panE:thioredoxin:PepT-like:Poorly characterized:Nucleotide Metabolism:Metabolism of Other Amino Acids:Metabolism of Cofactors and Vitamins:Genetic Information Processing:Translation:Global:Metabolism:Energy metabolism:Electron transport:Unknown function:Enzymes of unknown specificity:General:Biosynthesis of cofactors, prosthetic groups, and carriers:Pantothenate and coenzyme A:Thiamine:Information storage and processing:Cellular processes and signaling:Metabolism:Metabolism" 108 "Energy production and conversion:Predicted oxidoreductases (related to aryl-alcohol dehydrogenases):Putative intracellular protease/amidase:Phosphotransferase system cellobiose-specific component IIB:Phosphotransferase system cellobiose-specific component IIC:Nitrate/nitrite transporter:ABC-type phosphate/phosphonate transport system, ATPase component:ABC-type phosphate/phosphonate transport system, permease component:Uncharacterized protein conserved in bacteria:Carbohydrate transport and metabolism:Inorganic ion transport and metabolism:ABC transporters:Phosphotransferase system (PTS):General function prediction only:Function unknown:lacE:efflux_EmrB:hlyII:PhnE:ABC_phnC:spore_II_R:Signal transduction:Membrane Transport:Transport and binding proteins:Anions:Other:Cellular processes:Toxin production and resistance:Sporulation and germination:Environmental Information Processing:PTS:Metabolism:Poorly characterized" 109 "Proline racemase:Amino acid transport and metabolism:Arginine and proline metabolism:Metabolic pathways:spore_II_P:Metabolism:Metabolism:Cellular processes:Sporulation and germination:Metabolism:Global:Amino Acid Metabolism" 110 "Energy production and conversion:Glutamate-1-semialdehyde aminotransferase:GTP cyclohydrolase I:Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase:ATP-dependent Zn proteases:NTP pyrophosphohydrolases including oxidative damage repair enzymes:Predicted oxidoreductases (related to aryl-alcohol dehydrogenases):Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, beta subunit:Na+/H+ antiporter NhaD and related arsenite permeases:ATP-dependent protease Clp, ATPase subunit:Hemolysins and related proteins containing CBS domains:Peroxiredoxin:Di- and tripeptidases:Uncharacterized small membrane protein:3-carboxymuconate cyclase:Amino acid transport and metabolism:Carbohydrate transport and metabolism:Coenzyme transport and metabolism:Replication, recombination and repair:Posttranslational modification, protein turnover, chaperones:Inorganic ion transport and metabolism:Citrate cycle (TCA cycle):Pentose phosphate pathway:Purine metabolism:Carbon fixation pathways in prokaryotes:Vitamin B6 metabolism:Folate biosynthesis:Porphyrin and chlorophyll metabolism:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:General function prediction only:Function unknown:folE:HMP-P_kinase:clpX:hemL:FtsH_fam:PepT-like:PorB_KorB:Metabolism:Global:Metabolism of Cofactors and Vitamins:Nucleotide Metabolism:Energy Metabolism:Thiamine:Carbohydrate Metabolism:Information storage and processing:Cellular processes and signaling:Metabolism:Poorly characterized:Heme, porphyrin, and cobalamin:Folic acid:Biosynthesis of cofactors, prosthetic groups, and carriers:Degradation of proteins, peptides, and glycopeptides:Protein fate:Metabolism" 111 "Energy production and conversion:FAD/FMN-containing dehydrogenases:Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II:Predicted phosphatase/phosphohexomutase:ABC-type sugar transport systems, permease components:Monoamine oxidase:Uncharacterized conserved protein:Uncharacterized protein conserved in bacteria:Predicted membrane protein:Proline racemase:Phage-related minor tail protein:Amino acid transport and metabolism:Carbohydrate transport and metabolism:Lipid transport and metabolism:Fatty acid metabolism:Glycine serine and threonine metabolism:Arginine and proline metabolism:Histidine metabolism:Tyrosine metabolism:Phenylalanine metabolism:Tryptophan metabolism:Phosphonate and phosphinate metabolism:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:ABC transporters:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:Function unknown:phosphonatase:bact_FAD_ox:tape_meas_TP901:TIGR03943:Poorly characterized:Metabolism:Prophage functions:Mobile and extrachromosomal element functions:Other:Central intermediary metabolism:Metabolism:Metabolism:Global:Membrane Transport:Environmental Information Processing:Metabolism of Other Amino Acids:Amino Acid Metabolism:Lipid Metabolism" 112 "Energy production and conversion:Acetyl-CoA acetyltransferase:Exopolyphosphatase:Protein-tyrosine-phosphatase:Adenine deaminase:Enoyl-CoA hydratase/carnithine racemase:3-hydroxyacyl-CoA dehydrogenase:Transcriptional regulator:Acetyltransferases, including N-acetylases of ribosomal proteins:Acyl-CoA dehydrogenases:Electron transfer flavoprotein, beta subunit:Aminoglycoside N3'-acetyltransferase:Penicillin V acylase and related amidases:Nucleotide transport and metabolism:Lipid transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:Cell wall/membrane/envelope biogenesis:Inorganic ion transport and metabolism:Fatty acid metabolism:Synthesis and degradation of ketone bodies:Secondary bile acid biosynthesis:Purine metabolism:Valine leucine and isoleucine degradation:Geraniol degradation:Lysine degradation:Benzoate degradation:Tryptophan metabolism:beta-Alanine metabolism:alpha-Linolenic acid metabolism:Pyruvate metabolism:Naphthalene degradation:Aminobenzoate degradation:Glyoxylate and dicarboxylate metabolism:Propanoate metabolism:Ethylbenzene degradation:Butanoate metabolism:Carbon fixation pathways in prokaryotes:Terpenoid backbone biosynthesis:Limonene and pinene degradation:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:Two-component system:Signal transduction mechanisms:AcCoA-C-Actrans:Defense mechanisms:Other:Fatty acid and phospholipid metabolism:Metabolism:Global:Metabolism:Signal Transduction:Environmental Information Processing:Xenobiotics Biodegradation and Metabolism:Metabolism of Terpenoids and Polyketides:Metabolism of Other Amino Acids:Amino Acid Metabolism:Nucleotide Metabolism:Lipid Metabolism:Energy Metabolism:Metabolism:Carbohydrate Metabolism:Cellular processes and signaling:Information storage and processing" 113 "Short-chain dehydrogenases of various substrate specificities:Predicted flavoprotein:Zn-dependent hydrolases, including glyoxylases:SAM-dependent methyltransferases:Cytosine/adenosine deaminases:Signal transduction histidine kinase:Nucleoside phosphorylase:N-acetylglutamate synthase and related acetyltransferases:Acetyltransferases, including N-acetylases of ribosomal proteins:Cyclopropane fatty acid synthase and related methyltransferases:Uncharacterized protein conserved in bacteria:Predicted membrane protein:Amino acid transport and metabolism:Nucleotide transport and metabolism:Translation, ribosomal structure and biogenesis:Cell wall/membrane/envelope biogenesis:Cysteine and methionine metabolism:Arginine and proline metabolism:Metabolic pathways:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:Function unknown:Signal transduction mechanisms:MTA/SAH-Nsdase:Amino Acid Metabolism:Metabolism:Metabolism:Cellular processes and signaling:Information storage and processing:Salvage of nucleosides and nucleotides:Purines, pyrimidines, nucleosides, and nucleotides:Metabolism:Global:Poorly characterized" 114 "Fructose-2,6-bisphosphatase:Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases):Sugar phosphate isomerases/epimerases:ABC-type antimicrobial peptide transport system, ATPase component:DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog:Predicted membrane protein:FOG: PKD repeat:Carbohydrate transport and metabolism:Lipid transport and metabolism:Transcription:Tyrosine metabolism:Benzoate degradation:Naphthalene degradation:Aminobenzoate degradation:Ethylbenzene degradation:Limonene and pinene degradation:Microbial metabolism in diverse environments:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:Function unknown:sigma70-ECF:Defense mechanisms:Metabolism:Amino Acid Metabolism:Metabolism of Terpenoids and Polyketides:Xenobiotics Biodegradation and Metabolism:Global:Metabolism:Information storage and processing:Cellular processes and signaling:Metabolism:Poorly characterized" 115 "Xaa-Pro aminopeptidase:Hydrogenase maturation factor:Mannose-6-phosphate isomerase:Na+/alanine symporter:Transcriptional regulator, contains sigma factor-related N-terminal domain:Uncharacterized protein conserved in bacteria:Amino acid transport and metabolism:Carbohydrate transport and metabolism:Transcription:Posttranslational modification, protein turnover, chaperones:Function unknown:agcS:hypE:Metabolism:Cellular processes and signaling:Information storage and processing:Poorly characterized" 116 "Energy production and conversion:Transaldolase:Pyrroline-5-carboxylate reductase:Lactoylglutathione lyase and related lyases:Protein-tyrosine-phosphatase:Cytosine deaminase and related metal-dependent hydrolases:Uncharacterized NAD(FAD)-dependent dehydrogenases:NADPH:quinone reductase and related Zn-dependent oxidoreductases:Aldo/keto reductases, related to diketogulonate reductase:Predicted permeases:NAD-dependent aldehyde dehydrogenases:Predicted 6-phosphogluconate dehydrogenase:Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases):Sugar (pentulose and hexulose) kinases:ABC-type proline/glycine betaine transport systems, ATPase components:Periplasmic glycine betaine/choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein):NADH:flavin oxidoreductases, Old Yellow Enzyme family:Uncharacterized oxidoreductases, Fe-dependent alcohol dehydrogenase family:Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases:H+/gluconate symporter and related permeases:Predicted dithiol-disulfide isomerase involved in polyketide biosynthesis:Arabinose efflux permease:Amino acid transport and metabolism:Nucleotide transport and metabolism:Carbohydrate transport and metabolism:Lipid transport and metabolism:Cell wall/membrane/envelope biogenesis:Glycolysis / Gluconeogenesis:Pentose phosphate pathway:Pentose and glucuronate interconversions:Fructose and mannose metabolism:Ascorbate and aldarate metabolism:Fatty acid biosynthesis:Fatty acid metabolism:Oxidative phosphorylation:Pyrimidine metabolism:Valine leucine and isoleucine degradation:Lysine degradation:Arginine and proline metabolism:Histidine metabolism:Bisphenol degradation:Tryptophan metabolism:beta-Alanine metabolism:Glutathione metabolism:Glycerolipid metabolism:Pyruvate metabolism:Chloroalkane and chloroalkene degradation:Propanoate metabolism:Butanoate metabolism:Limonene and pinene degradation:Biosynthesis of unsaturated fatty acids:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:ABC transporters:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:Signal transduction mechanisms:proC:gntP:gnd_rel:fsa_talC_mipB:proV:gntK_FGGY:oxido_grp_1:Membrane Transport:Environmental Information Processing:Amino acids, peptides and amines:Transport and binding proteins:Xenobiotics Biodegradation and Metabolism:Sugars:Metabolism of Terpenoids and Polyketides:Pentose phosphate pathway:Energy metabolism:Metabolism of Other Amino Acids:Metabolism:Amino Acid Metabolism:Nucleotide Metabolism:Lipid Metabolism:Energy Metabolism:Enzymes of unknown specificity:Carbohydrate Metabolism:Amino acid biosynthesis:Glutamate family:Cellular processes and signaling:Metabolism:Poorly characterized:Unknown function:Metabolism:Global:Carbohydrates, organic alcohols, and acids" 117 "Peptidyl-tRNA hydrolase:Uncharacterized conserved protein:Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain:ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components:Zn-dependent proteases:Transcriptional accessory protein:Predicted Zn-dependent hydrolases of the beta-lactamase fold:Membrane protein involved in the export of O-antigen and teichoic acid:Predicted ABC-type exoprotein transport system, permease component:Predicted membrane protein:Uncharacterized protein conserved in bacteria:Coenzyme transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:Inorganic ion transport and metabolism:Oxidative phosphorylation:Metabolic pathways:Two-component system:General function prediction only:Function unknown:Signal transduction mechanisms:pth:Intracellular trafficking, secretion, and vesicular transport:Signal Transduction:Environmental Information Processing:Metabolism:Energy Metabolism:Poorly characterized:Cellular processes and signaling:Metabolism:Information storage and processing:Other:Protein synthesis:Metabolism:Global" 118 "Mismatch repair ATPase (MutS family):Lipoate synthase:Nucleoside-diphosphate-sugar epimerases:ATPase involved in DNA replication initiation:Fe2+/Zn2+ uptake regulation proteins:Predicted endonuclease involved in recombination (possible Holliday junction resolvase in Mycoplasmas and B. subtilis):Predicted transcriptional regulator, consists of a Zn-ribbon and ATP-cone domains:Acetyltransferases, including N-acetylases of ribosomal proteins:Cation transport ATPase:Uncharacterized conserved protein:Uncharacterized protein conserved in bacteria:Membrane protein involved in cytochrome C biogenesis:Carbohydrate transport and metabolism:Coenzyme transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:Replication, recombination and repair:Cell wall/membrane/envelope biogenesis:Posttranslational modification, protein turnover, chaperones:Inorganic ion transport and metabolism:Tyrosine metabolism:Benzoate degradation:Naphthalene degradation:Aminobenzoate degradation:Ethylbenzene degradation:Lipoic acid metabolism:Limonene and pinene degradation:Metabolic pathways:Microbial metabolism in diverse environments:Two-component system:Mismatch repair:Function unknown:TIGR00244:RNAse_H_YqgF:DnaA:lipA:mutS1:ATPase_P-type:Cellular processes and signaling:Amino Acid Metabolism:Metabolism of Cofactors and Vitamins:Metabolism of Terpenoids and Polyketides:Xenobiotics Biodegradation and Metabolism:Genetic Information Processing:Replication and Repair:Environmental Information Processing:Signal Transduction:Global:Metabolism:Regulatory functions:DNA interactions:DNA metabolism:DNA replication, recombination, and repair:Unknown function:General:Biosynthesis of cofactors, prosthetic groups, and carriers:Lipoate:Information storage and processing:Metabolism:Metabolism:Poorly characterized" 119 "N-formylmethionyl-tRNA deformylase:Diaminopimelate epimerase:Uncharacterized conserved protein:Molybdopterin biosynthesis enzymes:Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases:Predicted permease:Fe2+/Zn2+ uptake regulation proteins:Molybdopterin-guanine dinucleotide biosynthesis protein A:DNA-binding ferritin-like protein (oxidative damage protectant):Transcriptional regulators, similar to M. xanthus CarD:Amidases related to nicotinamidase:Arsenate reductase and related proteins, glutaredoxin family:Predicted transcriptional regulators:Predicted transcriptional regulators:Phage shock protein A (IM30), suppresses sigma54-dependent transcription:Uncharacterized protein conserved in bacteria:Leucyl aminopeptidase (aminopeptidase T):AT-rich DNA-binding protein:Amino acid transport and metabolism:Coenzyme transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:Inorganic ion transport and metabolism:Lysine biosynthesis:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:Function unknown:Signal transduction mechanisms:TIGR00049:pept_deformyl:molyb_syn:parB_part:DapF:arsC_related:dipeptidaselike:Protein fate:DNA interactions:Regulatory functions:Metabolism:Global:Poorly characterized:Amino Acid Metabolism:Metabolism:Cellular processes and signaling:Information storage and processing:Metabolism:Other:Biosynthesis of cofactors, prosthetic groups, and carriers:Aspartate family:Amino acid biosynthesis:Protein modification and repair" 120 "Predicted sugar kinase:Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase:Acetyl-CoA acetyltransferase:Predicted hydrolases of the HAD superfamily:Sec-independent protein secretion pathway component TatC:Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases):ADP-ribose pyrophosphatase:Transcriptional regulators:Sec-independent protein secretion pathway components:Acyl dehydratase:Putative enzyme of poly-gamma-glutamate biosynthesis (capsule formation):Poly(3-hydroxyalkanoate) synthetase:Protein involved in biosynthesis of mitomycin antibiotics/polyketide fumonisin:Amino acid transport and metabolism:Nucleotide transport and metabolism:Carbohydrate transport and metabolism:Coenzyme transport and metabolism:Lipid transport and metabolism:Transcription:Cell wall/membrane/envelope biogenesis:Fatty acid metabolism:Synthesis and degradation of ketone bodies:Valine leucine and isoleucine degradation:Lysine degradation:Arginine and proline metabolism:Phenylalanine metabolism:Benzoate degradation:Tryptophan metabolism:D-Arginine and D-ornithine metabolism:D-Alanine metabolism:Pyruvate metabolism:Glyoxylate and dicarboxylate metabolism:Propanoate metabolism:Butanoate metabolism:Carbon fixation pathways in prokaryotes:Nicotinate and nicotinamide metabolism:Terpenoid backbone biosynthesis:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:Two-component system:Protein export:Bacterial secretion system:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:Cof-subfamily:tatC:D_amino_aminoT:tatAE:AcAcCoA_reduct:PHA_synth_III_C:AcCoA-C-Actrans:phaP_Bmeg:phaR_Bmeg:Intracellular trafficking, secretion, and vesicular transport:Biosynthesis:Carbohydrate Metabolism:Energy Metabolism:Lipid Metabolism:Amino Acid Metabolism:Metabolism of Other Amino Acids:Metabolism of Cofactors and Vitamins:Metabolism of Terpenoids and Polyketides:Xenobiotics Biodegradation and Metabolism:Genetic Information Processing:Folding Sorting and Degradation:Environmental Information Processing:Membrane Transport:Signal Transduction:Global:Metabolism:Energy metabolism:Amino acids and amines:Fatty acid and phospholipid metabolism:Other:Metabolism:Protein fate:Protein and peptide secretion and trafficking:Unknown function:Enzymes of unknown specificity:Information storage and processing:Cellular processes and signaling:Metabolism:Poorly characterized" 121 "Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), B subunit:Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), A subunit:Nucleotidyltransferase/DNA polymerase involved in DNA repair:RecA/RadA recombinase:ATP-dependent exoDNAse (exonuclease V) beta subunit (contains helicase and exonuclease domains):ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components:Uncharacterized low-complexity proteins:Uncharacterized metal-binding protein:Uncharacterized protein conserved in bacteria:Uncharacterized conserved protein:Uncharacterized protein conserved in bacteria:ATP-dependent nuclease, subunit B:Uncharacterized protein conserved in bacteria:Superfamily I DNA and RNA helicases:Transcriptional regulator, effector-binding domain/component:Coenzyme transport and metabolism:Transcription:Replication, recombination and repair:Inorganic ion transport and metabolism:Histidine metabolism:Tyrosine metabolism:Selenocompound metabolism:Polycyclic aromatic hydrocarbon degradation:Microbial metabolism in diverse environments:Nucleotide excision repair:Mismatch repair:Homologous recombination:General function prediction only:Function unknown:Signal transduction mechanisms:parE_Gpos:parC_Gpos:tigrfam_recA:addB_Gpos:addA_Gpos:Cellular processes and signaling:Information storage and processing:DNA replication, recombination, and repair:DNA metabolism:Metabolism:Metabolism:Global:Replication and Repair:Genetic Information Processing:Xenobiotics Biodegradation and Metabolism:Metabolism of Other Amino Acids:Poorly characterized:Amino Acid Metabolism:Metabolism" 122 "Glutamate-1-semialdehyde aminotransferase:Delta-aminolevulinic acid dehydratase:Porphobilinogen deaminase:Guanosine polyphosphate pyrophosphohydrolases/synthetases:Glutamyl-tRNA reductase:Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family:Thioredoxin reductase:ABC-type Fe3+-siderophore transport system, permease component:ABC-type Fe3+-hydroxamate transport system, periplasmic component:ABC-type transport system involved in cytochrome c biogenesis, permease component:Glutamate racemase:D-Tyr-tRNAtyr deacylase:Uroporphyrinogen-III synthase:ATPase related to the helicase subunit of the Holliday junction resolvase:Predicted membrane protein:Carbohydrate transport and metabolism:Coenzyme transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:Replication, recombination and repair:Cell wall/membrane/envelope biogenesis:Posttranslational modification, protein turnover, chaperones:Inorganic ion transport and metabolism:Purine metabolism:Pyrimidine metabolism:D-Glutamine and D-glutamate metabolism:Streptomycin biosynthesis:Inositol phosphate metabolism:Porphyrin and chlorophyll metabolism:Metabolic pathways:Biosynthesis of secondary metabolites:ABC transporters:Function unknown:Signal transduction mechanisms:glut_race:hemC:TIGR00256:spoT_relA:hemL:hemA:DNA_bind_RsfA:Bthiol_YpdA:Poorly characterized:Carbohydrate Metabolism:Nucleotide Metabolism:Metabolism of Other Amino Acids:Metabolism of Cofactors and Vitamins:Biosynthesis of Other Secondary Metabolites:Environmental Information Processing:Membrane Transport:Global:Metabolism:Protein synthesis:tRNA aminoacylation:Cellular processes:Adaptations to atypical conditions:Sporulation and germination:Unknown function:Enzymes of unknown specificity:Biosynthesis of cofactors, prosthetic groups, and carriers:Heme, porphyrin, and cobalamin:Cell envelope:Biosynthesis and degradation of murein sacculus and peptidoglycan:Information storage and processing:Cellular processes and signaling:Metabolism:Metabolism" 123 "Aspartate-semialdehyde dehydrogenase:Ribosomal protein L33:Predicted hydrolase of the metallo-beta-lactamase superfamily:Predicted hydrolase (HAD superfamily):ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component:ABC-type multidrug transport system, ATPase component:Predicted metal-dependent membrane protease:Putative multicopper oxidases:Uncharacterized enzyme involved in biosynthesis of extracellular polysaccharides:Amino acid transport and metabolism:Translation, ribosomal structure and biogenesis:Inorganic ion transport and metabolism:Glycine serine and threonine metabolism:Cysteine and methionine metabolism:Lysine biosynthesis:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:ABC transporters:Ribosome:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:MG423:rpmG_bact:asd_B:HAD-SF-IA-v1:SASP_H:Defense mechanisms:Information storage and processing:Amino Acid Metabolism:Genetic Information Processing:Translation:Environmental Information Processing:Membrane Transport:Global:Metabolism:Protein synthesis:Ribosomal proteins: synthesis and modification:Cellular processes:Sporulation and germination:Hypothetical proteins:Conserved:Unknown function:Enzymes of unknown specificity:Amino acid biosynthesis:Aspartate family:Metabolism:Cellular processes and signaling:Metabolism:Poorly characterized" 124 "ABC-type antimicrobial peptide transport system, permease component:Membrane-fusion protein:ABC-type antimicrobial peptide transport system, ATPase component:Transcriptional regulator:Uncharacterized protein conserved in bacteria:Transcription:Cell wall/membrane/envelope biogenesis:ABC transporters:Function unknown:lytR_cpsA_psr:yxeA_fam:RND_mfp:Defense mechanisms:Information storage and processing:Membrane Transport:Regulatory functions:Other:Transport and binding proteins:Unknown substrate:Hypothetical proteins:Conserved:Environmental Information Processing:Cellular processes and signaling:Poorly characterized" 125 "Energy production and conversion:Predicted dehydrogenases and related proteins:Predicted xylanase/chitin deacetylase:Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain:Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases):Predicted acetyltransferases and hydrolases with the alpha/beta hydrolase fold:Na+/alanine symporter:Uncharacterized proteins, homologs of microcin C7 resistance protein MccF:L-lactate permease:Transcriptional regulators:Transcriptional regulator, contains sigma factor-related N-terminal domain:Arabinose efflux permease:Uncharacterized protein conserved in bacteria:Uncharacterized protein conserved in bacteria:Predicted integral membrane protein:Amino acid transport and metabolism:Carbohydrate transport and metabolism:Lipid transport and metabolism:Transcription:Fatty acid biosynthesis:Biosynthesis of unsaturated fatty acids:Metabolic pathways:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:Function unknown:Signal transduction mechanisms:agcS:Defense mechanisms:Lipid Metabolism:Poorly characterized:Metabolism:Cellular processes and signaling:Information storage and processing:Metabolism:Global:Metabolism" 126 "Glycine cleavage system H protein (lipoate-binding):Predicted hydrolases of the HAD superfamily:Arsenite efflux pump ACR3 and related permeases:Uncharacterized conserved protein:Predicted transcriptional regulators:Arsenate reductase and related proteins, glutaredoxin family:Uncharacterized conserved protein:Predicted transcriptional regulators:Predicted drug exporters of the RND superfamily:Uncharacterized protein conserved in bacteria:Amino acid transport and metabolism:Transcription:Inorganic ion transport and metabolism:General function prediction only:Function unknown:Cof-subfamily:parB_part:gcvH:arsC_related:Energy metabolism:Enzymes of unknown specificity:Poorly characterized:Information storage and processing:Metabolism:Unknown function:DNA interactions:Regulatory functions:Amino acids and amines" 127 "Cystathionine beta-lyases/cystathionine gamma-synthases:Metal-dependent hydrolases of the beta-lactamase superfamily III:Transcriptional regulator:Phosphotransferase system cellobiose-specific component IIC:Metal-dependent amidase/aminoacylase/carboxypeptidase:Amino acid transport and metabolism:Carbohydrate transport and metabolism:Transcription:Cysteine and methionine metabolism:Lysine biosynthesis:Selenocompound metabolism:Phosphotransferase system (PTS):General function prediction only:cello_pts_IIC:hlyII:met_gam_lyase:B_ant_repeat:amidohydrolases:B_an_ocin:Protein fate:Amino Acid Metabolism:Metabolism of Other Amino Acids:Environmental Information Processing:Membrane Transport:Energy metabolism:Amino acids and amines:Metabolism:Degradation of proteins, peptides, and glycopeptides:Cellular processes:Toxin production and resistance:Signal transduction:PTS:Information storage and processing:Metabolism:Poorly characterized" 128 "Threonine dehydrogenase and related Zn-dependent dehydrogenases:Amino acid transport and metabolism:Glycolysis / Gluconeogenesis:Fatty acid metabolism:Tyrosine metabolism:Chloroalkane and chloroalkene degradation:Naphthalene degradation:Methane metabolism:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:General function prediction only:spore_YpeB:TIGR04086_membr:Metabolism:Carbohydrate Metabolism:Energy Metabolism:Lipid Metabolism:Amino Acid Metabolism:Xenobiotics Biodegradation and Metabolism:Global:Metabolism:Cellular processes:Sporulation and germination:Metabolism:Poorly characterized" 129 "Energy production and conversion:N-formylmethionyl-tRNA deformylase:Glutamate dehydrogenase/leucine dehydrogenase:Lactoylglutathione lyase and related lyases:Predicted hydrolases of the HAD superfamily:Glycerophosphoryl diester phosphodiesterase:Universal stress protein UspA and related nucleotide-binding proteins:Carbonic anhydrases/acetyltransferases, isoleucine patch superfamily:Preprotein translocase subunit YidC:DNA-binding ferritin-like protein (oxidative damage protectant):Predicted RNA binding protein (contains ribosomal protein S1 domain):Arsenate reductase and related proteins, glutaredoxin family:Ribosome-associated protein Y (PSrp-1):Phage shock protein A (IM30), suppresses sigma54-dependent transcription:Transcriptional regulators:Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases:Predicted nucleotidyltransferase:Amino acid transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:Inorganic ion transport and metabolism:Alanine aspartate and glutamate metabolism:Arginine and proline metabolism:Glycerophospholipid metabolism:Nitrogen metabolism:Metabolic pathways:Protein export:Bacterial secretion system:General function prediction only:Signal transduction mechanisms:pept_deformyl:Cof-subfamily:yfiA:arsC_related:yidC_oxa1_cterm:Intracellular trafficking, secretion, and vesicular transport:Unknown function:Energy Metabolism:Lipid Metabolism:Amino Acid Metabolism:Genetic Information Processing:Folding Sorting and Degradation:Environmental Information Processing:Membrane Transport:Global:Metabolism:Regulatory functions:DNA interactions:Protein synthesis:Translation factors:Protein fate:Protein and peptide secretion and trafficking:Protein modification and repair:Metabolism:Enzymes of unknown specificity:Information storage and processing:Cellular processes and signaling:Metabolism:Poorly characterized" 130 "Acetyltransferase (isoleucine patch superfamily):Zn-dependent hydrolases, including glyoxylases:Bacterial cell division membrane protein:Predicted hydrolase (HAD superfamily):Putative threonine efflux protein:Arabinose efflux permease:Signal transduction histidine kinase:Cell cycle control, cell division, chromosome partitioning:Amino acid transport and metabolism:Carbohydrate transport and metabolism:Pyruvate metabolism:General function prediction only:Signal transduction mechanisms:2A0309:LPXTG_anchor:HAD-SF-IA-v1:spore_III_AD:spore_ger_x_C:Other:Carbohydrate Metabolism:Transport and binding proteins:Amino acids, peptides and amines:Cellular processes:Sporulation and germination:Unknown function:Enzymes of unknown specificity:Cell envelope:Metabolism:Cellular processes and signaling:Metabolism:Poorly characterized" 131 "Energy production and conversion:Amino acid transporters:Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases):Threonine dehydrogenase and related Zn-dependent dehydrogenases:Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs:Metal-dependent amidase/aminoacylase/carboxypeptidase:Uncharacterized protein conserved in bacteria:Cephalosporin hydroxylase:Plastocyanin:Amino acid transport and metabolism:Lipid transport and metabolism:Transcription:Glycolysis / Gluconeogenesis:Fatty acid biosynthesis:Fatty acid metabolism:Arginine and proline metabolism:Tyrosine metabolism:Chloroalkane and chloroalkene degradation:Naphthalene degradation:Methane metabolism:Biosynthesis of unsaturated fatty acids:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:Function unknown:amidohydrolases:spore_YyaC:spore_III_AC:spore_ylbJ:spore_ger_x_C:Defense mechanisms:Metabolism:Cellular processes and signaling:Information storage and processing:Sporulation and germination:Cellular processes:Degradation of proteins, peptides, and glycopeptides:Protein fate:Metabolism:Metabolism:Global:Xenobiotics Biodegradation and Metabolism:Amino Acid Metabolism:Lipid Metabolism:Energy Metabolism:Poorly characterized:Carbohydrate Metabolism" 132 "Energy production and conversion:Fructose-2,6-bisphosphatase:Pyruvate kinase:NTP pyrophosphohydrolases including oxidative damage repair enzymes:SAM-dependent methyltransferases:Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily):NAD-dependent aldehyde dehydrogenases:Transcriptional regulators of sugar metabolism:ABC-type sugar transport system, periplasmic component:Carbohydrate transport and metabolism:Transcription:Replication, recombination and repair:Glycolysis / Gluconeogenesis:Purine metabolism:Alanine aspartate and glutamate metabolism:Arginine and proline metabolism:Tyrosine metabolism:Pyruvate metabolism:Butanoate metabolism:Methane metabolism:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:ABC transporters:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:pyruv_kin:SSADH:BioC:Biotin:Information storage and processing:Metabolism:Poorly characterized:Biosynthesis of cofactors, prosthetic groups, and carriers:Glycolysis/gluconeogenesis:Energy metabolism:Other:Central intermediary metabolism:Metabolism:Metabolism:Global:Membrane Transport:Environmental Information Processing:Amino Acid Metabolism:Nucleotide Metabolism:Energy Metabolism:Carbohydrate Metabolism" 133 "Energy production and conversion:Cytosine deaminase and related metal-dependent hydrolases:Pseudouridylate synthases, 23S RNA-specific:Glycerol uptake facilitator and related permeases (Major Intrinsic Protein Family):Predicted transcriptional regulators:ABC-type metal ion transport system, periplasmic component/surface adhesin:Na+/H+ antiporter NhaD and related arsenite permeases:Na+/H+-dicarboxylate symporters:Transcriptional regulator:Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily:Uncharacterized conserved protein:Thymidine kinase:D-alanyl-D-alanine carboxypeptidase:Nucleoside permease:Glutaminase:Arabinose efflux permease:Amino acid transport and metabolism:Nucleotide transport and metabolism:Carbohydrate transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:Cell wall/membrane/envelope biogenesis:Inorganic ion transport and metabolism:Pyrimidine metabolism:Alanine aspartate and glutamate metabolism:Arginine and proline metabolism:D-Glutamine and D-glutamate metabolism:Nitrogen metabolism:Metabolic pathways:Microbial metabolism in diverse environments:ABC transporters:General function prediction only:Function unknown:rluA_subfam:lytR_cpsA_psr:nupC:Gln_ase:Information storage and processing:Energy Metabolism:Nucleotide Metabolism:Amino Acid Metabolism:Metabolism of Other Amino Acids:Environmental Information Processing:Membrane Transport:Global:Metabolism:Energy metabolism:Amino acids and amines:Regulatory functions:Other:Protein synthesis:tRNA and rRNA base modification:Transport and binding proteins:Nucleosides, purines and pyrimidines:Metabolism:Cellular processes and signaling:Metabolism:Poorly characterized" 134 "Energy production and conversion:S-adenosylmethionine synthetase:Malic enzyme:Glucosamine 6-phosphate synthetase, contains amidotransferase and phosphosugar isomerase domains:Amino acid transporters:Cytosine/adenosine deaminases:ABC-type Fe3+-siderophore transport system, permease component:Predicted permease:Branched-chain amino acid permeases:GTPase:Na+/H+-dicarboxylate symporters:Uncharacterized membrane protein, required for spore maturation in B.subtilis.:Septum formation inhibitor-activating ATPase:ABC-type phosphate/phosphonate transport system, ATPase component:ABC-type phosphate/phosphonate transport system, permease component:Predicted symporter:Cell cycle control, cell division, chromosome partitioning:Amino acid transport and metabolism:Nucleotide transport and metabolism:Coenzyme transport and metabolism:Translation, ribosomal structure and biogenesis:Cell wall/membrane/envelope biogenesis:Inorganic ion transport and metabolism:Alanine aspartate and glutamate metabolism:Cysteine and methionine metabolism:Selenocompound metabolism:Amino sugar and nucleotide sugar metabolism:Pyruvate metabolism:Metabolic pathways:Biosynthesis of secondary metabolites:ABC transporters:Two-component system:General function prediction only:livcs:sss:metK:PhnE:glmS:minD_bact:ABC_phnC:Poorly characterized:Metabolism:Cellular processes and signaling:Information storage and processing:Cell division:Cellular processes:Cations and iron carrying compounds:Anions:Amino acids, peptides and amines:Transport and binding proteins:Other:Amino sugars:Central intermediary metabolism:Metabolism:Metabolism:Global:Signal Transduction:Membrane Transport:Environmental Information Processing:Metabolism of Other Amino Acids:Amino Acid Metabolism:Carbohydrate Metabolism" 135 "Energy production and conversion:Dethiobiotin synthetase:7-keto-8-aminopelargonate synthetase and related enzymes:4-aminobutyrate aminotransferase and related aminotransferases:Adenosylmethionine-8-amino-7-oxononanoate aminotransferase:Thiamine biosynthesis protein ThiC:Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily):ABC-type multidrug transport system, ATPase component:Type II secretory pathway, component PulF:Metal-dependent amidase/aminoacylase/carboxypeptidase:ABC-type Na+ efflux pump, permease component:Type II secretory pathway, ATPase PulE/Tfp pilus assembly pathway, ATPase PilB:Arabinose efflux permease:Uncharacterized protein conserved in bacteria:Competence protein ComGF:Uncharacterized protein conserved in bacteria:Amino acid transport and metabolism:Carbohydrate transport and metabolism:Coenzyme transport and metabolism:Cell motility:Inorganic ion transport and metabolism:Alanine aspartate and glutamate metabolism:Valine leucine and isoleucine degradation:Arginine and proline metabolism:beta-Alanine metabolism:Propanoate metabolism:Butanoate metabolism:Thiamine metabolism:Biotin metabolism:Metabolic pathways:Biosynthesis of secondary metabolites:ABC transporters:General function prediction only:Function unknown:thiC:bioD:bioA:GABAtrnsam:bioF:2A0309:yxeA_fam:amidohydrolases:IV_pilin_GFxxxE:Intracellular trafficking, secretion, and vesicular transport:Defense mechanisms:Metabolism:Carbohydrate Metabolism:Amino Acid Metabolism:Metabolism of Other Amino Acids:Metabolism of Cofactors and Vitamins:Environmental Information Processing:Membrane Transport:Global:Metabolism:Central intermediary metabolism:Other:Protein fate:Protein and peptide secretion and trafficking:Degradation of proteins, peptides, and glycopeptides:Transport and binding proteins:Amino acids, peptides and amines:Hypothetical proteins:Conserved:Biosynthesis of cofactors, prosthetic groups, and carriers:Biotin:Thiamine:Cellular processes and signaling:Metabolism:Poorly characterized" 136 "ATPase components of ABC transporters with duplicated ATPase domains:Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily):Predicted membrane-associated Zn-dependent proteases 1:DNA-directed RNA polymerase specialized sigma subunit:Uncharacterized conserved protein:Predicted membrane protein:Transcription:Cell wall/membrane/envelope biogenesis:Alanine aspartate and glutamate metabolism:Arginine and proline metabolism:Nitrogen metabolism:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:RNA polymerase:General function prediction only:Function unknown:2A0309:asn_synth_AEB:spore_sigG:spore_IV_B:spore_III_AF:spore_safA:antibiot_sagB:Sporulation and germination:Amino acid biosynthesis:Aspartate family:Information storage and processing:Cellular processes and signaling:Poorly characterized:Cellular processes:Amino acids, peptides and amines:Transport and binding proteins:Metabolism:Metabolism:Global:Transcription:Genetic Information Processing:Amino Acid Metabolism:Energy Metabolism" 137 "Prephenate dehydratase:Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase:ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component:Zn-dependent hydrolases, including glyoxylases:IMP dehydrogenase/GMP reductase:ABC-type dipeptide/oligopeptide/nickel transport systems, permease components:Oligoendopeptidase F:ABC-type dipeptide/oligopeptide/nickel transport systems, permease components:DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog:Acetyltransferases, including N-acetylases of ribosomal proteins:Predicted metal-dependent hydrolase:Uncharacterized protein conserved in bacteria:Predicted acetyltransferase:Tryptophan 2,3-dioxygenase (vermilion):Kynureninase:ABC-type oligopeptide transport system, periplasmic component:Short-chain alcohol dehydrogenase of unknown specificity:ABC-type uncharacterized transport system, periplasmic component:ABC-type oligopeptide transport system, ATPase component:Ornithine/acetylornithine aminotransferase:Amino acid transport and metabolism:Nucleotide transport and metabolism:Coenzyme transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:Inorganic ion transport and metabolism:Purine metabolism:Valine leucine and isoleucine degradation:Valine leucine and isoleucine biosynthesis:Arginine and proline metabolism:Tryptophan metabolism:Phenylalanine tyrosine and tryptophan biosynthesis:Pantothenate and CoA biosynthesis:Metabolic pathways:Biosynthesis of secondary metabolites:ABC transporters:RNA polymerase:General function prediction only:Function unknown:pepF:ilvE_I:IMP_dehydrog:oligo_HPY:kynureninase:Orn_aminotrans:spore_sigH:trp_arylform:trp_2_3_diox:Information storage and processing:Pyruvate family:Amino acid biosynthesis:Sporulation and germination:Cellular processes:Amino acids, peptides and amines:Transport and binding proteins:Degradation of proteins, peptides, and glycopeptides:Protein fate:Purine ribonucleotide biosynthesis:Purines, pyrimidines, nucleosides, and nucleotides:Amino acids and amines:Energy metabolism:Metabolism:Metabolism:Global:Membrane Transport:Environmental Information Processing:Transcription:Genetic Information Processing:Metabolism of Cofactors and Vitamins:Amino Acid Metabolism:Poorly characterized:Nucleotide Metabolism:Metabolism" 138 "Methyl-accepting chemotaxis protein:Enoyl-CoA hydratase/carnithine racemase:Imidazolonepropionase and related amidohydrolases:DNA replication protein:S-adenosylmethionine decarboxylase:Urocanate hydratase:Amino acid transport and metabolism:Lipid transport and metabolism:Replication, recombination and repair:Cell motility:Fatty acid metabolism:Cysteine and methionine metabolism:Valine leucine and isoleucine degradation:Geraniol degradation:Lysine degradation:Arginine and proline metabolism:Histidine metabolism:Benzoate degradation:Tryptophan metabolism:beta-Alanine metabolism:Glutathione metabolism:Aminobenzoate degradation:Propanoate metabolism:Butanoate metabolism:Limonene and pinene degradation:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:Two-component system:Bacterial chemotaxis:Secondary metabolites biosynthesis, transport and catabolism:Signal transduction mechanisms:hutI:hutU:excise:SAM_DCase_Bsu:Metabolism of Terpenoids and Polyketides:Metabolism:Metabolism of Other Amino Acids:Amino Acid Metabolism:Lipid Metabolism:Xenobiotics Biodegradation and Metabolism:Carbohydrate Metabolism:Environmental Information Processing:Signal Transduction:Cellular Processes:Cell Motility:Global:Metabolism:Central intermediary metabolism:Polyamine biosynthesis:Energy metabolism:Amino acids and amines:Unknown function:General:Information storage and processing:Cellular processes and signaling:Metabolism" 139 "Energy production and conversion:Tyrosyl-tRNA synthetase:Predicted methyltransferases:Na+/proline symporter:Lipoprotein signal peptidase:N-acetylmuramoyl-L-alanine amidase:Na+/H+ antiporter NhaD and related arsenite permeases:Uncharacterized ABC-type transport system, permease component:Branched-chain amino acid permeases:Na+/alanine symporter:Uncharacterized conserved protein:Metal-dependent amidase/aminoacylase/carboxypeptidase:Transcriptional regulators:Uncharacterized proteins, homologs of microcin C7 resistance protein MccF:D-alanyl-D-alanine carboxypeptidase:Na+/H+ antiporter:Predicted acetyltransferase:Predicted membrane protein:Beta- N-acetylglucosaminidase:ABC-type uncharacterized transport system, periplasmic component:Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain:Amino acid transport and metabolism:Carbohydrate transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:Cell wall/membrane/envelope biogenesis:Inorganic ion transport and metabolism:Methane metabolism:Aminoacyl-tRNA biosynthesis:Protein export:General function prediction only:Function unknown:Signal transduction mechanisms:lspA:TIGR00096:sensory_box:tyrS:livcs:sss:agcS:antiport_nhaC:amidohydrolases:Intracellular trafficking, secretion, and vesicular transport:Defense mechanisms:Poorly characterized:Metabolism:Cellular processes and signaling:Information storage and processing:Enzymes of unknown specificity:Unknown function:Cations and iron carrying compounds:Amino acids, peptides and amines:Transport and binding proteins:Degradation of proteins, peptides, and glycopeptides:Protein and peptide secretion and trafficking:Protein fate:tRNA aminoacylation:Protein synthesis:Small molecule interactions:Regulatory functions:Metabolism:Folding Sorting and Degradation:Translation:Genetic Information Processing:Energy Metabolism" 140 "Predicted membrane protein:Function unknown:Poorly characterized" 141 "Fructose-2,6-bisphosphatase:Dienelactone hydrolase and related enzymes:ATPase involved in DNA repair:NTP pyrophosphohydrolases including oxidative damage repair enzymes:Uncharacterized membrane-associated protein:ABC-type nitrate/sulfonate/bicarbonate transport system, permease component:Cell division protein FtsI/penicillin-binding protein 2:ABC-type antimicrobial peptide transport system, ATPase component:Uncharacterized conserved protein:Predicted transcriptional regulators:Phosphatidylserine/phosphatidylglycerophosphate/cardiolipin synthases and related enzymes:SOS-response transcriptional repressors (RecA-mediated autopeptidases):AraC-type DNA-binding domain-containing proteins:Uncharacterized protein conserved in bacteria:Transposase and inactivated derivatives:Predicted metal-dependent hydrolases related to alanyl-tRNA synthetase HxxxH domain:Uncharacterized conserved protein:Predicted integral membrane protein:Carbohydrate transport and metabolism:Lipid transport and metabolism:Transcription:Replication, recombination and repair:Cell wall/membrane/envelope biogenesis:Inorganic ion transport and metabolism:Glycolysis / Gluconeogenesis:Glycerophospholipid metabolism:Methane metabolism:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:ABC transporters:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:Function unknown:Signal transduction mechanisms:lexA:Ku_bact:cognate_SipW:Defense mechanisms:Metabolism:Carbohydrate Metabolism:Poorly characterized:Cellular processes and signaling:Information storage and processing:DNA replication, recombination, and repair:DNA metabolism:DNA interactions:Metabolism:Regulatory functions:Metabolism:Global:Membrane Transport:Environmental Information Processing:Lipid Metabolism:Energy Metabolism" 142 "Predicted EndoIII-related endonuclease:Predicted membrane protein:RNase P protein component:Predicted transcriptional regulators:Predicted membrane protein, hemolysin III homolog:Uncharacterized conserved protein:Thymidine kinase:Uncharacterized stress-induced protein:Predicted RNA-binding protein:Transcriptional antiterminator:Nucleotide transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:Replication, recombination and repair:Pyrimidine metabolism:Glycerolipid metabolism:Glycerophospholipid metabolism:Metabolic pathways:Base excision repair:General function prediction only:Function unknown:TIGR00023:rnpA:TIGR00255:hlyIII:nth:DNA_bind_RsfA:Information storage and processing:Lipid Metabolism:Nucleotide Metabolism:Genetic Information Processing:Replication and Repair:Global:Metabolism:Fatty acid and phospholipid metabolism:Biosynthesis:DNA metabolism:DNA replication, recombination, and repair:Transcription:RNA processing:Cellular processes:Sporulation and germination:Hypothetical proteins:Conserved:Metabolism:Metabolism:Poorly characterized" 143 "Energy production and conversion:Dihydroorotase and related cyclic amidohydrolases:Dihydroorotate dehydrogenase:Superfamily I DNA and RNA helicases:Orotidine-5'-phosphate decarboxylase:Carbamoylphosphate synthase large subunit (split gene in MJ):Orotate phosphoribosyltransferase:Carbamoylphosphate synthase small subunit:Aspartate carbamoyltransferase, catalytic chain:2-polyprenylphenol hydroxylase and related flavodoxin oxidoreductases:UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase:Cell division protein FtsI/penicillin-binding protein 2:UDP-N-acetylmuramyl tripeptide synthase:UDP-N-acetylmuramate dehydrogenase:Superfamily I DNA and RNA helicases and helicase subunits:Gamma-aminobutyrate permease and related permeases:Uncharacterized conserved protein:Cell division septal protein:Pyrimidine operon attenuation protein/uracil phosphoribosyltransferase:Xanthine/uracil permeases:Signal transduction histidine kinase:Amino acid transport and metabolism:Nucleotide transport and metabolism:Coenzyme transport and metabolism:Replication, recombination and repair:Cell wall/membrane/envelope biogenesis:Pyrimidine metabolism:Alanine aspartate and glutamate metabolism:Lysine biosynthesis:Amino sugar and nucleotide sugar metabolism:Peptidoglycan biosynthesis:Metabolic pathways:Nucleotide excision repair:Mismatch repair:Function unknown:Signal transduction mechanisms:murB:sensory_box:tRNA_RlmH_YbeA:pyrE:asp_carb_tr:ncs2:pyrC_multi:pyrD_sub1_fam:murE:murG:CPSaseIIsmall:CPSaseII_lrg:pyrF:spoVD_pbp:Small molecule interactions:Regulatory functions:Pyrimidine ribonucleotide biosynthesis:Purines, pyrimidines, nucleosides, and nucleotides:Metabolism:Metabolism:Global:Replication and Repair:Genetic Information Processing:Glycan Biosynthesis and Metabolism:Amino Acid Metabolism:Nucleotide Metabolism:Nucleosides, purines and pyrimidines:Carbohydrate Metabolism:Cellular processes:Sporulation and germination:Cell envelope:Biosynthesis and degradation of murein sacculus and peptidoglycan:Information storage and processing:Cellular processes and signaling:Metabolism:Poorly characterized:Transport and binding proteins:tRNA and rRNA base modification:Protein synthesis" 144 "Arabinose efflux permease:Carbohydrate transport and metabolism:Metabolism" 145 "Asp-tRNAAsn/Glu-tRNAGln amidotransferase B subunit (PET112 homolog):Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases:Ribonucleotide reductase, beta subunit:Superfamily I DNA and RNA helicases:ATP-dependent exoDNAse (exonuclease V), alpha subunit - helicase superfamily I member:Asp-tRNAAsn/Glu-tRNAGln amidotransferase C subunit:Predicted rRNA methylase:Uncharacterized protein conserved in bacteria:Membrane protein involved in the export of O-antigen and teichoic acid:Penicillin-binding protein-related factor A, putative recombinase:Protein involved in sex pheromone biosynthesis:Nucleotide transport and metabolism:Translation, ribosomal structure and biogenesis:Replication, recombination and repair:Purine metabolism:Pyrimidine metabolism:Aminoacyl-tRNA biosynthesis:Metabolic pathways:Nucleotide excision repair:Mismatch repair:Homologous recombination:General function prediction only:Function unknown:gatA:gatB:gatC:tly:recU:pcrA:recD_rel:Information storage and processing:Nucleotide Metabolism:Genetic Information Processing:Translation:Replication and Repair:Global:Metabolism:DNA metabolism:DNA replication, recombination, and repair:Protein synthesis:tRNA aminoacylation:Unknown function:Enzymes of unknown specificity:General:Metabolism:Metabolism:Poorly characterized" 146 "Energy production and conversion:Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases:Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II:NTP pyrophosphohydrolases including oxidative damage repair enzymes:Predicted transcriptional regulators:Signal peptidase I:NAD-dependent aldehyde dehydrogenases:UDP-glucose 4-epimerase:Gamma-aminobutyrate permease and related permeases:DNA-directed RNA polymerase specialized sigma subunit:Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes:Acetyltransferases, including N-acetylases of ribosomal proteins:Predicted membrane protein:Uncharacterized conserved protein:Amino acid transport and metabolism:Lipid transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:Replication, recombination and repair:Cell wall/membrane/envelope biogenesis:Glycolysis / Gluconeogenesis:Citrate cycle (TCA cycle):Pentose and glucuronate interconversions:Galactose metabolism:Ascorbate and aldarate metabolism:Fatty acid metabolism:Glycine serine and threonine metabolism:Valine leucine and isoleucine degradation:Lysine degradation:Arginine and proline metabolism:Histidine metabolism:Phenylalanine metabolism:Tryptophan metabolism:beta-Alanine metabolism:Cyanoamino acid metabolism:Amino sugar and nucleotide sugar metabolism:Glycerolipid metabolism:Pyruvate metabolism:Chloroalkane and chloroalkene degradation:Aminobenzoate degradation:Propanoate metabolism:Styrene degradation:Limonene and pinene degradation:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:RNA polymerase:Protein export:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:Function unknown:YbaK_EbsC:galE:lipoamide_DH:GABAperm:sigpep_I_bact:spore_sigI:Intracellular trafficking, secretion, and vesicular transport:Metabolism:Poorly characterized:Sporulation and germination:Cellular processes:Amino acids, peptides and amines:Transport and binding proteins:Protein and peptide secretion and trafficking:Protein fate:Sugars:Energy metabolism:Metabolism:Metabolism:Global:Folding Sorting and Degradation:Transcription:Genetic Information Processing:Xenobiotics Biodegradation and Metabolism:Metabolism of Terpenoids and Polyketides:Metabolism of Other Amino Acids:Amino Acid Metabolism:Lipid Metabolism:Unknown function:Carbohydrate Metabolism:General:Information storage and processing:Cellular processes and signaling" 147 "Predicted Fe-S oxidoreductases:Signal transduction histidine kinase:Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain:Actin-like ATPase involved in cell morphogenesis:16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases:Methylase of chemotaxis methyl-accepting proteins:Uncharacterized conserved protein:Predicted transcriptional regulator containing the HTH domain:D-alanyl-D-alanine carboxypeptidase:Uncharacterized bacitracin resistance protein:Nucleoside permease:Uncharacterized protein conserved in bacteria:Cell cycle control, cell division, chromosome partitioning:Nucleotide transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:Cell wall/membrane/envelope biogenesis:Cell motility:Peptidoglycan biosynthesis:Two-component system:Bacterial chemotaxis:General function prediction only:Function unknown:Signal transduction mechanisms:TIGR00093:TIGR00281:mreB:Defense mechanisms:Cell Motility:Cellular Processes:Signal Transduction:Environmental Information Processing:Biosynthesis and degradation of murein sacculus and peptidoglycan:Glycan Biosynthesis and Metabolism:Information storage and processing:Cellular processes and signaling:Metabolism:Poorly characterized:Cell envelope:tRNA and rRNA base modification:Protein synthesis:Metabolism:Chromosome-associated proteins:DNA metabolism" 148 "Pyrroline-5-carboxylate reductase:Predicted hydrolases of the HAD superfamily:D-alanyl-D-alanine carboxypeptidase:Glycerol-3-phosphate responsive antiterminator (mRNA-binding):Permeases:Protein tyrosine/serine phosphatase:Sortase (surface protein transpeptidase):Amino acid transport and metabolism:Transcription:Cell wall/membrane/envelope biogenesis:Arginine and proline metabolism:Metabolic pathways:Biosynthesis of secondary metabolites:General function prediction only:Signal transduction mechanisms:Cof-subfamily:proC:sortase_fam:Information storage and processing:Amino Acid Metabolism:Global:Metabolism:Protein fate:Protein and peptide secretion and trafficking:Unknown function:Enzymes of unknown specificity:Amino acid biosynthesis:Glutamate family:Metabolism:Cellular processes and signaling:Metabolism:Poorly characterized" 149 "Replicative DNA helicase:Flagellin and related hook-associated proteins:DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog:Transcription:Replication, recombination and repair:Cell motility:Two-component system:Flagellar assembly:DNA replication:DnaB:sigma70-ECF:DNA metabolism:DNA replication, recombination, and repair:Information storage and processing:Cellular processes and signaling:Genetic Information Processing:Cell Motility:Cellular Processes:Signal Transduction:Environmental Information Processing:Replication and Repair" 150 "Biotin synthase and related enzymes:Predicted permeases:ABC-type transport system involved in cytochrome c biogenesis, permease component:Non-ribosomal peptide synthetase modules and related proteins:Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases):ADP-ribose pyrophosphatase:ABC-type multidrug transport system, ATPase component:Phosphoserine aminotransferase:Arabinose efflux permease:SH3 domain protein:Uncharacterized conserved protein:Amino acid transport and metabolism:Nucleotide transport and metabolism:Carbohydrate transport and metabolism:Coenzyme transport and metabolism:Lipid transport and metabolism:Posttranslational modification, protein turnover, chaperones:Pentose phosphate pathway:Oxidative phosphorylation:Glycine serine and threonine metabolism:Methane metabolism:Vitamin B6 metabolism:Biotin metabolism:Metabolic pathways:Microbial metabolism in diverse environments:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:Function unknown:Signal transduction mechanisms:bioB:serC_1:AA-adenyl-dom:cytochr_II_ccsB:Defense mechanisms:Cellular processes and signaling:Carbohydrate Metabolism:Energy Metabolism:Amino Acid Metabolism:Metabolism of Cofactors and Vitamins:Global:Metabolism:Protein fate:Protein modification and repair:Amino acid biosynthesis:Serine family:Biosynthesis of cofactors, prosthetic groups, and carriers:Biotin:Metabolism:Metabolism:Poorly characterized" 151 "Glycosyltransferase:Predicted transcriptional regulators:Uncharacterized conserved protein:Transcription:Cell wall/membrane/envelope biogenesis:Fructose and mannose metabolism:Function unknown:spore_yhbH:Cellular processes and signaling:Carbohydrate Metabolism:Cellular processes:Sporulation and germination:Information storage and processing:Metabolism:Poorly characterized" 152 "Energy production and conversion:Glutamate-1-semialdehyde aminotransferase:Xaa-Pro aminopeptidase:GTP cyclohydrolase I:ATP-dependent Zn proteases:Ribosomal protein S1:ABC-type transport system involved in Fe-S cluster assembly, permease component:Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, beta subunit:ATP-dependent protease Clp, ATPase subunit:Uncharacterized proteins, LmbE homologs:Uncharacterized small membrane protein:Arabinose efflux permease:Amino acid transport and metabolism:Carbohydrate transport and metabolism:Coenzyme transport and metabolism:Translation, ribosomal structure and biogenesis:Posttranslational modification, protein turnover, chaperones:Citrate cycle (TCA cycle):Tyrosine metabolism:Benzoate degradation:Naphthalene degradation:Aminobenzoate degradation:Ethylbenzene degradation:Carbon fixation pathways in prokaryotes:Folate biosynthesis:Porphyrin and chlorophyll metabolism:Limonene and pinene degradation:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:Ribosome:Function unknown:folE:clpX:hemL:FtsH_fam:sufB:PorB_KorB:thiol_BshB2:Information storage and processing:Cellular processes and signaling:Metabolism:Poorly characterized:Heme, porphyrin, and cobalamin:Folic acid:Other:Biosynthesis of cofactors, prosthetic groups, and carriers:Degradation of proteins, peptides, and glycopeptides:Protein fate:Metabolism:Metabolism:Global:Translation:Genetic Information Processing:Xenobiotics Biodegradation and Metabolism:Metabolism of Terpenoids and Polyketides:Metabolism of Cofactors and Vitamins:Amino Acid Metabolism:Energy Metabolism:Glutathione and analogs:Carbohydrate Metabolism" 153 "Molybdopterin converting factor, large subunit:cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases:Permeases of the drug/metabolite transporter (DMT) superfamily:Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs:Monoamine oxidase:Molybdopterin converting factor, small subunit:Uncharacterized protein conserved in bacteria:Phage-related protein:Phage-related protein:Phage-related minor tail protein:Amino acid transport and metabolism:Carbohydrate transport and metabolism:Coenzyme transport and metabolism:Transcription:Glycine serine and threonine metabolism:Arginine and proline metabolism:Histidine metabolism:Tyrosine metabolism:Phenylalanine metabolism:Tryptophan metabolism:Metabolic pathways:Biosynthesis of secondary metabolites:Sulfur relay system:General function prediction only:Function unknown:Signal transduction mechanisms:put_anti_recept:moaD:tape_meas_TP901:Prophage functions:Mobile and extrachromosomal element functions:Metabolism:Global:Metabolism:Folding Sorting and Degradation:Genetic Information Processing:Cellular processes and signaling:Amino Acid Metabolism:Metabolism:Poorly characterized:Information storage and processing:Molybdopterin:Biosynthesis of cofactors, prosthetic groups, and carriers" 154 "Energy production and conversion:FAD/FMN-containing dehydrogenases:Short-chain dehydrogenases of various substrate specificities:Predicted amidohydrolase:Inosine-uridine nucleoside N-ribohydrolase:Uncharacterized protein conserved in bacteria:Predicted transcriptional regulator:ABC-type oligopeptide transport system, periplasmic component:Uncharacterized protein conserved in bacteria:Amino acid transport and metabolism:Nucleotide transport and metabolism:Transcription:Purine metabolism:Pyruvate metabolism:Nicotinate and nicotinamide metabolism:Metabolic pathways:ABC transporters:General function prediction only:Function unknown:Poorly characterized:Carbohydrate Metabolism:Nucleotide Metabolism:Metabolism of Cofactors and Vitamins:Environmental Information Processing:Membrane Transport:Global:Metabolism:Information storage and processing:Metabolism:Metabolism" 155 "Methyl-accepting chemotaxis protein:Na+/alanine symporter:Beta-lactamase class C and other penicillin binding proteins:Cu/Zn superoxide dismutase:Uncharacterized protein conserved in bacteria:Amino acid transport and metabolism:Cell motility:Inorganic ion transport and metabolism:Two-component system:Bacterial chemotaxis:Protein export:Function unknown:Signal transduction mechanisms:agcS:sigpep_I_arch:cognate_SipW:Defense mechanisms:Metabolism:Folding Sorting and Degradation:Environmental Information Processing:Signal Transduction:Cellular Processes:Cell Motility:Cellular processes and signaling:Genetic Information Processing:Poorly characterized" 156 "Glycosidases:Metal-dependent amidase/aminoacylase/carboxypeptidase:Aspartate racemase:Putative glucose uptake permease:Carbohydrate transport and metabolism:Cell wall/membrane/envelope biogenesis:Alanine aspartate and glutamate metabolism:Arginine and proline metabolism:Starch and sucrose metabolism:Metabolic pathways:Biosynthesis of secondary metabolites:General function prediction only:asp_race:RhaT:amidohydrolases:Amino acids and amines:Carbohydrate Metabolism:Amino Acid Metabolism:Global:Metabolism:Energy metabolism:Metabolism:Protein fate:Degradation of proteins, peptides, and glycopeptides:Transport and binding proteins:Carbohydrates, organic alcohols, and acids:Cellular processes and signaling:Metabolism:Poorly characterized" 157 "Pseudouridylate synthase:Xanthosine triphosphate pyrophosphatase:GMP synthase, PP-ATPase domain/subunit:ABC-type cobalt transport system, permease component CbiQ and related transporters:Predicted permeases:Chemotaxis signal transduction protein:ABC-type cobalt transport system, ATPase component:Flagellar biosynthesis pathway, component FliP:Flagellar biosynthesis pathway, component FlhB:Flagellar biosynthesis pathway, component FliR:Flagellar motor switch/type III secretory pathway protein:Flagellar biosynthesis pathway, component FliQ:Nucleotide transport and metabolism:Translation, ribosomal structure and biogenesis:Cell motility:Inorganic ion transport and metabolism:Purine metabolism:Thiamine metabolism:Metabolic pathways:ABC transporters:Two-component system:Bacterial chemotaxis:Flagellar assembly:General function prediction only:Signal transduction mechanisms:TIGR00042:hisT_truA:guaA_Cterm:fliN:Intracellular trafficking, secretion, and vesicular transport:Poorly characterized:Nucleotide Metabolism:Metabolism of Cofactors and Vitamins:Environmental Information Processing:Membrane Transport:Signal Transduction:Cellular Processes:Cell Motility:Global:Metabolism:Purines, pyrimidines, nucleosides, and nucleotides:Purine ribonucleotide biosynthesis:DNA metabolism:DNA replication, recombination, and repair:Protein synthesis:tRNA and rRNA base modification:Cellular processes:Chemotaxis and motility:Information storage and processing:Cellular processes and signaling:Metabolism:Metabolism" 158 "Energy production and conversion:FAD/FMN-containing dehydrogenases:Superoxide dismutase:Signal peptidase I:Predicted xylanase/chitin deacetylase:Membrane protein TerC, possibly involved in tellurium resistance:Ribose/xylose/arabinose/galactoside ABC-type transport systems, permease components:Flagellar motor protein:Alkaline phosphatase:SOS-response transcriptional repressors (RecA-mediated autopeptidases):Pterin-4a-carbinolamine dehydratase:Predicted membrane protein:Putative Ser protein kinase:Phenylalanine-4-hydroxylase:Mn-containing catalase:Response regulator of citrate/malate metabolism:Uncharacterized protein conserved in bacteria:Amino acid transport and metabolism:Carbohydrate transport and metabolism:Coenzyme transport and metabolism:Transcription:Cell motility:Inorganic ion transport and metabolism:Phenylalanine metabolism:Bisphenol degradation:Phenylalanine tyrosine and tryptophan biosynthesis:Polycyclic aromatic hydrocarbon degradation:Aminobenzoate degradation:Folate biosynthesis:Limonene and pinene degradation:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:ABC transporters:Two-component system:Bacterial chemotaxis:Flagellar assembly:Protein export:Function unknown:Signal transduction mechanisms:lexA:LPXTG_anchor:sigpep_I_bact:spore_ybaN_pdaB:R_switched_YjbE:Intracellular trafficking, secretion, and vesicular transport:Poorly characterized:Amino Acid Metabolism:Metabolism of Cofactors and Vitamins:Metabolism of Terpenoids and Polyketides:Xenobiotics Biodegradation and Metabolism:Genetic Information Processing:Folding Sorting and Degradation:Environmental Information Processing:Membrane Transport:Signal Transduction:Cellular Processes:Cell Motility:Global:Metabolism:Regulatory functions:DNA interactions:Protein fate:Protein and peptide secretion and trafficking:Cellular processes:Sporulation and germination:Cell envelope:Other:Information storage and processing:Cellular processes and signaling:Metabolism:Metabolism" 159 "Amino acid transporters:Signal transduction histidine kinase:Phosphatidylserine decarboxylase:Predicted permeases:Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain:Transcriptional regulator:Predicted periplasmic solute-binding protein:D-alanyl-D-alanine carboxypeptidase:Arginine/lysine/ornithine decarboxylases:Dipeptide/tripeptide permease:Uncharacterized protein conserved in bacteria:Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein):Amino acid transport and metabolism:Lipid transport and metabolism:Transcription:Cell wall/membrane/envelope biogenesis:Arginine and proline metabolism:Glycerophospholipid metabolism:Metabolic pathways:General function prediction only:Function unknown:Signal transduction mechanisms:PS_decarb:TIGR00247:lytR_cpsA_psr:2A0302:LTA_DltD:Cellular processes and signaling:Lipid Metabolism:Amino Acid Metabolism:Global:Metabolism:Fatty acid and phospholipid metabolism:Biosynthesis:Regulatory functions:Other:Transport and binding proteins:Amino acids, peptides and amines:Hypothetical proteins:Conserved:Information storage and processing:Metabolism:Metabolism:Poorly characterized" 160 "Lyzozyme M1 (1,4-beta-N-acetylmuramidase):Uncharacterized stress protein (general stress protein 26):ABC-type uncharacterized transport system, periplasmic component:Uncharacterized protein conserved in bacteria:Cell wall/membrane/envelope biogenesis:Tyrosine metabolism:Benzoate degradation:Naphthalene degradation:Aminobenzoate degradation:Ethylbenzene degradation:Limonene and pinene degradation:Microbial metabolism in diverse environments:General function prediction only:Function unknown:Metabolism:Amino Acid Metabolism:Metabolism of Terpenoids and Polyketides:Xenobiotics Biodegradation and Metabolism:Global:Metabolism:Cellular processes and signaling:Poorly characterized" 161 "Energy production and conversion:Polyprenyltransferase (cytochrome oxidase assembly factor):L-asparaginase/archaeal Glu-tRNAGln amidotransferase subunit D:Na+/proline symporter:RNase P protein component:Predicted membrane metal-binding protein:Heme/copper-type cytochrome/quinol oxidases, subunit 1:L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases:Heme/copper-type cytochrome/quinol oxidases, subunit 2:Predicted phosphate-binding enzymes, TIM-barrel fold:Predicted SAM-dependent methyltransferase:Arabinose efflux permease:Uncharacterized protein conserved in bacteria:Amino acid transport and metabolism:Carbohydrate transport and metabolism:Translation, ribosomal structure and biogenesis:Posttranslational modification, protein turnover, chaperones:Oxidative phosphorylation:Alanine aspartate and glutamate metabolism:Cyanoamino acid metabolism:Porphyrin and chlorophyll metabolism:Terpenoid backbone biosynthesis:Nitrogen metabolism:Metabolic pathways:Biosynthesis of secondary metabolites:General function prediction only:Function unknown:rnpA:ComEC_N-term:YbgI_SA1388:asnASE_I:efflux_EmrB:sss:cyoE_ctaB:GGGP-family:IPP_isom_2:CoxB:CtaD_CoxA:Heme, porphyrin, and cobalamin:Information storage and processing:Cellular processes and signaling:Metabolism:Poorly characterized:General:Unknown function:Other:Cations and iron carrying compounds:Transport and binding proteins:RNA processing:Transcription:Electron transport:Energy metabolism:Metabolism:Metabolism:Global:Metabolism of Terpenoids and Polyketides:Metabolism of Cofactors and Vitamins:Metabolism of Other Amino Acids:Amino Acid Metabolism:Biosynthesis of cofactors, prosthetic groups, and carriers:Energy Metabolism:Other" 162 "Nucleoside-diphosphate-sugar epimerases:Kef-type K+ transport systems, membrane components:Signal peptidase I:ABC-type dipeptide/oligopeptide/nickel transport systems, permease components:Mismatch repair ATPase (MutS family):Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis/translation initiation factor 2B, gamma/epsilon subunits (eIF-2Bgamma/eIF-2Bepsilon):Phosphatidylserine/phosphatidylglycerophosphate/cardiolipin synthases and related enzymes:DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog:D-alanyl-D-alanine carboxypeptidase:Phosphopantetheinyl transferase:Permeases of the major facilitator superfamily:Predicted acetyltransferase:Predicted thioesterase involved in non-ribosomal peptide biosynthesis:Inhibitor of the KinA pathway to sporulation, predicted exonuclease:Amino acid transport and metabolism:Carbohydrate transport and metabolism:Coenzyme transport and metabolism:Lipid transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:Replication, recombination and repair:Cell wall/membrane/envelope biogenesis:Inorganic ion transport and metabolism:Tyrosine metabolism:Benzoate degradation:Starch and sucrose metabolism:Amino sugar and nucleotide sugar metabolism:Peptidoglycan biosynthesis:Glycerophospholipid metabolism:Naphthalene degradation:Aminobenzoate degradation:Ethylbenzene degradation:Limonene and pinene degradation:Biosynthesis of unsaturated fatty acids:Metabolic pathways:Microbial metabolism in diverse environments:ABC transporters:RNA polymerase:Protein export:Mismatch repair:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:pantethn_trn:2a37:sigpep_I_bact:CDP_4_6_dhtase:G1P_cyt_trans:spore_III_AB:spore_III_AC:sigma70-ECF:Intracellular trafficking, secretion, and vesicular transport:Metabolism:Poorly characterized:Information storage and processing:Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides:Cell envelope:Sporulation and germination:Cellular processes:Cations and iron carrying compounds:Transport and binding proteins:Protein modification and repair:Protein and peptide secretion and trafficking:Protein fate:Metabolism:Metabolism:Global:Membrane Transport:Environmental Information Processing:Replication and Repair:Folding Sorting and Degradation:Transcription:Genetic Information Processing:Xenobiotics Biodegradation and Metabolism:Metabolism of Terpenoids and Polyketides:Glycan Biosynthesis and Metabolism:Amino Acid Metabolism:Lipid Metabolism:Cellular processes and signaling:Carbohydrate Metabolism" 163 "Energy production and conversion:Tryptophanyl-tRNA synthetase:FAD/FMN-containing dehydrogenases:Acetyltransferases:ABC-type dipeptide/oligopeptide/nickel transport systems, permease components:Signal transduction histidine kinase:Signal peptidase I:Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain:Gamma-aminobutyrate permease and related permeases:DNA-directed RNA polymerase specialized sigma subunit:Hemolysins and related proteins containing CBS domains:DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog:Acetyltransferases, including N-acetylases of ribosomal proteins:Beta-lactamase class C and other penicillin binding proteins:Acyl dehydratase:Malate synthase:Uncharacterized protein conserved in bacteria:Uncharacterized conserved protein:Uncharacterized protein conserved in bacteria:Amino acid transport and metabolism:Lipid transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:Inorganic ion transport and metabolism:Tyrosine metabolism:Benzoate degradation:Tryptophan metabolism:Pyruvate metabolism:Naphthalene degradation:Aminobenzoate degradation:Glyoxylate and dicarboxylate metabolism:Ethylbenzene degradation:Limonene and pinene degradation:Aminoacyl-tRNA biosynthesis:Metabolic pathways:Microbial metabolism in diverse environments:ABC transporters:RNA polymerase:Protein export:General function prediction only:Function unknown:Signal transduction mechanisms:trpS:malate_syn_A:GABAperm:sigpep_I_bact:spore_sigI:sigma70-ECF:Intracellular trafficking, secretion, and vesicular transport:Defense mechanisms:Poorly characterized:Carbohydrate Metabolism:Amino Acid Metabolism:Metabolism of Terpenoids and Polyketides:Xenobiotics Biodegradation and Metabolism:Genetic Information Processing:Transcription:Translation:Folding Sorting and Degradation:Environmental Information Processing:Membrane Transport:Global:Metabolism:Energy metabolism:TCA cycle:Protein synthesis:tRNA aminoacylation:Protein fate:Protein and peptide secretion and trafficking:Transport and binding proteins:Amino acids, peptides and amines:Cellular processes:Sporulation and germination:Information storage and processing:Cellular processes and signaling:Metabolism:Metabolism" 164 "Energy production and conversion:Co-chaperonin GroES (HSP10):Dephospho-CoA kinase:Formamidopyrimidine-DNA glycosylase:ABC-type transport system involved in Fe-S cluster assembly, ATPase component:Molecular chaperone:Chaperonin GroEL (HSP60 family):DnaJ-class molecular chaperone with C-terminal Zn finger domain:Selenocysteine lyase:Molecular chaperone GrpE (heat shock protein):ABC-type transport system involved in Fe-S cluster assembly, permease component:DNA polymerase I - 3'-5' exonuclease and polymerase domains:NifU homolog involved in Fe-S cluster formation:Transcriptional regulator of heat shock gene:Predicted membrane protein:Ribosomal protein L11 methylase:Amino acid transport and metabolism:Coenzyme transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:Replication, recombination and repair:Posttranslational modification, protein turnover, chaperones:Purine metabolism:Pyrimidine metabolism:Selenocompound metabolism:Thiamine metabolism:Pantothenate and CoA biosynthesis:Metabolic pathways:RNA degradation:DNA replication:Base excision repair:Nucleotide excision repair:Homologous recombination:Function unknown:TIGR00152:hrcA:prmA:fpg:pola:sufC:sufS:sufB:sufD:SUF_scaf_2:GroEL:DnaJ_bact:prok_dnaK:spore_YtaF:Pantothenate and coenzyme A:Nucleotide Metabolism:Metabolism of Other Amino Acids:Metabolism of Cofactors and Vitamins:Genetic Information Processing:Folding Sorting and Degradation:Replication and Repair:Global:Metabolism:Regulatory functions:DNA interactions:DNA metabolism:DNA replication, recombination, and repair:Protein synthesis:Ribosomal proteins: synthesis and modification:Protein fate:Protein folding and stabilization:Cellular processes:Sporulation and germination:Biosynthesis of cofactors, prosthetic groups, and carriers:Other:Metabolism:Information storage and processing:Cellular processes and signaling:Metabolism:Poorly characterized" 165 "Uncharacterized conserved protein:Function unknown:SASP_sspK:Cellular processes:Sporulation and germination:Poorly characterized" 166 "Energy production and conversion:Thiol-disulfide isomerase and thioredoxins:Predicted transcriptional regulators:Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family:Bacterial nucleoid DNA-binding protein:Arsenate reductase and related proteins, glutaredoxin family:Uncharacterized conserved protein:Transcriptional regulators:Transcriptional regulators:Predicted membrane protein:Predicted membrane protein:Membrane protein involved in cytochrome C biogenesis:Uncharacterized protein conserved in bacteria:Transcription:Replication, recombination and repair:Posttranslational modification, protein turnover, chaperones:Inorganic ion transport and metabolism:Ribosome:Function unknown:rpmF_bact:thioredoxin:arsC_related:DivI1A_domain:Electron transport:Energy metabolism:Cellular processes and signaling:Translation:Metabolism:Poorly characterized:Genetic Information Processing:Information storage and processing:Ribosomal proteins: synthesis and modification:Protein synthesis:DNA interactions:Regulatory functions" 167 "Energy production and conversion:Malate/lactate dehydrogenases:Cation transport ATPase:Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2:cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases:NAD-dependent aldehyde dehydrogenases:Zn-dependent alcohol dehydrogenases:Pyruvate-formate lyase-activating enzyme:Cytochrome bd-type quinol oxidase, subunit 1:Cytochrome bd-type quinol oxidase, subunit 2:Oxygen-sensitive ribonucleoside-triphosphate reductase:L-lactate permease:Pyruvate-formate lyase:Formate/nitrite family of transporters:Predicted transcriptional regulator:Molybdenum cofactor biosynthesis enzyme:Uncharacterized protein conserved in bacteria:Predicted membrane protein, putative toxin regulator:ABC-type transport system involved in cytochrome bd biosynthesis, ATPase and permease components:Nucleotide transport and metabolism:Coenzyme transport and metabolism:Transcription:Posttranslational modification, protein turnover, chaperones:Inorganic ion transport and metabolism:Glycolysis / Gluconeogenesis:Fatty acid metabolism:Oxidative phosphorylation:Purine metabolism:Pyrimidine metabolism:Cysteine and methionine metabolism:Tyrosine metabolism:Benzoate degradation:Pyruvate metabolism:Dioxin degradation:Chloroalkane and chloroalkene degradation:Naphthalene degradation:Propanoate metabolism:Butanoate metabolism:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:ABC transporters:Sulfur relay system:General function prediction only:Function unknown:Signal transduction mechanisms:cydB:lctP:pyr_form_ly_1:ATPase_P-type:L-LDH-NAD:NrdD:PFLA:moaA:CydD:Molybdopterin:Carbohydrate Metabolism:Energy Metabolism:Lipid Metabolism:Nucleotide Metabolism:Amino Acid Metabolism:Xenobiotics Biodegradation and Metabolism:Genetic Information Processing:Folding Sorting and Degradation:Environmental Information Processing:Membrane Transport:Global:Metabolism:Energy metabolism:Electron transport:Fermentation:Glycolysis/gluconeogenesis:Purines, pyrimidines, nucleosides, and nucleotides:2'-Deoxyribonucleotide metabolism:Protein fate:Protein modification and repair:Transport and binding proteins:Carbohydrates, organic alcohols, and acids:Biosynthesis of cofactors, prosthetic groups, and carriers:Metabolism:Information storage and processing:Cellular processes and signaling:Metabolism:Poorly characterized" 168 "Xaa-Pro aminopeptidase:UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase:Monoamine oxidase:Uncharacterized conserved protein:Acetyltransferases, including N-acetylases of ribosomal proteins:Uncharacterized protein conserved in bacteria:Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains:ABC-type proline/glycine betaine transport system, ATPase component:Amino acid transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:Cell wall/membrane/envelope biogenesis:Glycine serine and threonine metabolism:Arginine and proline metabolism:Histidine metabolism:Tyrosine metabolism:Phenylalanine metabolism:Benzoate degradation:Tryptophan metabolism:Peptidoglycan biosynthesis:Naphthalene degradation:Aminobenzoate degradation:Ethylbenzene degradation:Limonene and pinene degradation:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:ABC transporters:Function unknown:Signal transduction mechanisms:proV:Information storage and processing:Amino Acid Metabolism:Glycan Biosynthesis and Metabolism:Metabolism of Terpenoids and Polyketides:Xenobiotics Biodegradation and Metabolism:Environmental Information Processing:Membrane Transport:Global:Metabolism:Transport and binding proteins:Amino acids, peptides and amines:Metabolism:Cellular processes and signaling:Metabolism:Poorly characterized" 169 "Energy production and conversion:Fructose/tagatose bisphosphate aldolase:6-phosphofructokinase:Uncharacterized conserved protein:Pyruvate kinase:Thiol-disulfide isomerase and thioredoxins:Fe2+/Zn2+ uptake regulation proteins:Membrane protein TerC, possibly involved in tellurium resistance:ABC-type Mn2+/Zn2+ transport systems, permease components:Phosphomannomutase:Na+/alanine symporter:ABC-type Mn/Zn transport systems, ATPase component:Ferredoxin:D-alanine-D-alanine ligase and related ATP-grasp enzymes:Uncharacterized conserved protein:Acetyltransferases, including N-acetylases of ribosomal proteins:Dipeptide/tripeptide permease:Amino acid transport and metabolism:Carbohydrate transport and metabolism:Translation, ribosomal structure and biogenesis:Cell wall/membrane/envelope biogenesis:Posttranslational modification, protein turnover, chaperones:Inorganic ion transport and metabolism:Glycolysis / Gluconeogenesis:Pentose phosphate pathway:Fructose and mannose metabolism:Galactose metabolism:Purine metabolism:Tyrosine metabolism:Benzoate degradation:D-Alanine metabolism:Starch and sucrose metabolism:Amino sugar and nucleotide sugar metabolism:Streptomycin biosynthesis:Peptidoglycan biosynthesis:Pyruvate metabolism:Naphthalene degradation:Aminobenzoate degradation:Ethylbenzene degradation:Methane metabolism:Limonene and pinene degradation:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:ABC transporters:Function unknown:cbbA:agcS:yjdL_sub1_fam:TIGR01033:pyruv_kin:D_ala_D_alaTIGR:PFKA_ATP:R_switched_YkoY:Metabolism:Poorly characterized:Biosynthesis and degradation of murein sacculus and peptidoglycan:Cell envelope:Amino acids, peptides and amines:Transport and binding proteins:DNA interactions:Regulatory functions:Glycolysis/gluconeogenesis:Energy metabolism:Metabolism:Global:Membrane Transport:Environmental Information Processing:Xenobiotics Biodegradation and Metabolism:Biosynthesis of Other Secondary Metabolites:Metabolism:Metabolism of Terpenoids and Polyketides:Glycan Biosynthesis and Metabolism:Metabolism of Other Amino Acids:Amino Acid Metabolism:Nucleotide Metabolism:Energy Metabolism:Information storage and processing:Carbohydrate Metabolism:Cellular processes and signaling" 170 "Pseudouridylate synthase:Glycosyltransferases involved in cell wall biogenesis:Mg2+ and Co2+ transporters:Predicted Zn-dependent peptidases:Phosphopantetheine adenylyltransferase:Predicted xylanase/chitin deacetylase:Uncharacterized protein conserved in bacteria:Uncharacterized conserved protein:Predicted Zn-dependent hydrolases of the beta-lactamase fold:Uncharacterized protein conserved in bacteria:Signal transduction histidine kinase, nitrogen specific:Uncharacterized protein conserved in bacteria:Carbohydrate transport and metabolism:Coenzyme transport and metabolism:Translation, ribosomal structure and biogenesis:Cell wall/membrane/envelope biogenesis:Inorganic ion transport and metabolism:Lysine degradation:Pantothenate and CoA biosynthesis:Biotin metabolism:Metabolic pathways:General function prediction only:Function unknown:Signal transduction mechanisms:hisT_truA:cyt_tran_rel:DegV:integ_memb_HG:Cellular processes and signaling:Information storage and processing:General:Unknown function:tRNA and rRNA base modification:Protein synthesis:Metabolism:Metabolism:Global:Metabolism of Cofactors and Vitamins:Poorly characterized:Amino Acid Metabolism:Metabolism" 171 "Subtilisin-like serine proteases:Zinc metalloprotease (elastase):FOG: PKD repeat:Metal-dependent hydrolase:Uncharacterized protein conserved in bacteria:Amino acid transport and metabolism:Posttranslational modification, protein turnover, chaperones:Inositol phosphate metabolism:Glycerophospholipid metabolism:Metabolic pathways:General function prediction only:Function unknown:hlyII:M6dom_TIGR03296:sphingomy:B_an_ocin:Toxin production and resistance:Carbohydrate Metabolism:Lipid Metabolism:Global:Metabolism:Cellular processes:Metabolism:Pathogenesis:Cellular processes and signaling:Metabolism:Poorly characterized" 172 "Signal peptidase I:Transcriptional regulator:Uncharacterized protein conserved in bacteria:Transcription:Protein export:Function unknown:sigpep_I_bact:Intracellular trafficking, secretion, and vesicular transport:Cellular processes and signaling:Folding Sorting and Degradation:Protein fate:Protein and peptide secretion and trafficking:Information storage and processing:Genetic Information Processing:Poorly characterized" 173 "Energy production and conversion:Zn-dependent hydrolases, including glyoxylases:Enoyl-CoA hydratase/carnithine racemase:Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases):Galactose-1-phosphate uridylyltransferase:Oligoendopeptidase F:Transcriptional regulator:Acetyltransferases, including N-acetylases of ribosomal proteins:Conserved protein/domain typically associated with flavoprotein oxygenases, DIM6/NTAB family:Uncharacterized enzyme involved in biosynthesis of extracellular polysaccharides:Peptidase E:DNA gyrase inhibitor:Amino acid transport and metabolism:Lipid transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:Replication, recombination and repair:Fatty acid metabolism:Synthesis and degradation of ketone bodies:Valine leucine and isoleucine degradation:Geraniol degradation:Lysine degradation:Benzoate degradation:Tryptophan metabolism:beta-Alanine metabolism:Aminobenzoate degradation:Propanoate metabolism:Butanoate metabolism:Limonene and pinene degradation:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:PHB_DH:M3_not_pepF:Global:Metabolism:Xenobiotics Biodegradation and Metabolism:Poorly characterized:Metabolism of Terpenoids and Polyketides:Metabolism:Metabolism of Other Amino Acids:Amino Acid Metabolism:Lipid Metabolism:Metabolism:Information storage and processing:Carbohydrate Metabolism" 174 "Trk-type K+ transport systems, membrane components:Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily):MoxR-like ATPases:Predicted membrane protein:Retron-type reverse transcriptase:Phage-related protein:Replication, recombination and repair:Inorganic ion transport and metabolism:Arginine and proline metabolism:General function prediction only:Function unknown:2a38:put_anti_recept:tape_meas_TP901:exospor_lead:Information storage and processing:Amino Acid Metabolism:Transport and binding proteins:Cations and iron carrying compounds:Cellular processes:Sporulation and germination:Mobile and extrachromosomal element functions:Prophage functions:Metabolism:Metabolism:Poorly characterized" 175 "Organic radical activating enzymes:Transcriptional regulators:Acetyltransferases, including N-acetylases of ribosomal proteins:Transcriptional regulator/sugar kinase:Peptidylarginine deiminase and related enzymes:Amino acid transport and metabolism:Carbohydrate transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:Posttranslational modification, protein turnover, chaperones:Glycolysis / Gluconeogenesis:Galactose metabolism:Arginine and proline metabolism:Starch and sucrose metabolism:Amino sugar and nucleotide sugar metabolism:Streptomycin biosynthesis:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:ROK_glcA_fam:NrdG:Protein fate:Carbohydrate Metabolism:Amino Acid Metabolism:Biosynthesis of Other Secondary Metabolites:Global:Metabolism:Metabolism:Protein modification and repair:Unknown function:General:Information storage and processing:Cellular processes and signaling:Metabolism" 176 "Predicted S-adenosylmethionine-dependent methyltransferase:ATPases involved in chromosome partitioning:Topoisomerase IA:ABC-type multidrug transport system, ATPase component:L-serine deaminase:D-alanyl-D-alanine carboxypeptidase:GTPases:Putative enzyme of poly-gamma-glutamate biosynthesis (capsule formation):Capsular polysaccharide biosynthesis protein:Capsular polysaccharide biosynthesis protein:Cell cycle control, cell division, chromosome partitioning:Amino acid transport and metabolism:Carbohydrate transport and metabolism:Replication, recombination and repair:Cell wall/membrane/envelope biogenesis:Glycine serine and threonine metabolism:Cysteine and methionine metabolism:Peptidoglycan biosynthesis:Metabolic pathways:Biosynthesis of secondary metabolites:ABC transporters:General function prediction only:TIGR00091:sda_alpha:sda_beta:eps_fam:topB:spore_ypjB:GTP_HflX:Defense mechanisms:Information storage and processing:Amino Acid Metabolism:Glycan Biosynthesis and Metabolism:Environmental Information Processing:Membrane Transport:Global:Metabolism:Energy metabolism:Glycolysis/gluconeogenesis:DNA metabolism:DNA replication, recombination, and repair:Protein synthesis:tRNA and rRNA base modification:Transport and binding proteins:Carbohydrates, organic alcohols, and acids:Cellular processes:Sporulation and germination:Unknown function:General:Metabolism:Cellular processes and signaling:Metabolism:Poorly characterized" 177 "Quinolinate synthase:Signal transduction histidine kinase:Phosphopantetheinyl transferase (holo-ACP synthase):Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain:Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain:Uncharacterized membrane protein, required for spore maturation in B.subtilis.:Predicted membrane protein:Coenzyme transport and metabolism:Lipid transport and metabolism:Transcription:Valine leucine and isoleucine degradation:Glyoxylate and dicarboxylate metabolism:Propanoate metabolism:Carbon fixation pathways in prokaryotes:Nicotinate and nicotinamide metabolism:Pantothenate and CoA biosynthesis:Metabolic pathways:Microbial metabolism in diverse environments:General function prediction only:Function unknown:Signal transduction mechanisms:acpS:nadA:Biosynthesis of cofactors, prosthetic groups, and carriers:Carbohydrate Metabolism:Energy Metabolism:Amino Acid Metabolism:Metabolism of Cofactors and Vitamins:Global:Metabolism:Fatty acid and phospholipid metabolism:Biosynthesis:Metabolism:Pyridine nucleotides:Information storage and processing:Cellular processes and signaling:Metabolism:Poorly characterized" 178 "Energy production and conversion:Isopropylmalate/homocitrate/citramalate synthases:Ribose 5-phosphate isomerase:2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway):Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases:Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2:NADH:ubiquinone oxidoreductase 49 kD subunit 7:Cell wall-associated hydrolases (invasion-associated proteins):Acyl CoA:acetate/3-ketoacid CoA transferase, alpha subunit:4-hydroxyphenylpyruvate dioxygenase and related hemolysins:Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta):Amino acid transport and metabolism:Carbohydrate transport and metabolism:Coenzyme transport and metabolism:Lipid transport and metabolism:Cell wall/membrane/envelope biogenesis:Glycolysis / Gluconeogenesis:Pentose phosphate pathway:Synthesis and degradation of ketone bodies:Ubiquinone and other terpenoid-quinone biosynthesis:Oxidative phosphorylation:Valine leucine and isoleucine degradation:Geraniol degradation:Tyrosine metabolism:Phenylalanine metabolism:Pyruvate metabolism:Naphthalene degradation:Glyoxylate and dicarboxylate metabolism:Propanoate metabolism:Butanoate metabolism:Methane metabolism:Carbon fixation pathways in prokaryotes:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:rpiA:4HPPD:phage_arpU:pcaI_scoA_fam:spore_V_AD:DNA interactions:Carbohydrate Metabolism:Energy Metabolism:Lipid Metabolism:Amino Acid Metabolism:Metabolism of Cofactors and Vitamins:Metabolism of Terpenoids and Polyketides:Xenobiotics Biodegradation and Metabolism:Global:Metabolism:Energy metabolism:Amino acids and amines:Pentose phosphate pathway:Regulatory functions:Metabolism:Cellular processes:Sporulation and germination:Cellular processes and signaling:Metabolism:Poorly characterized" 179 "Energy production and conversion:Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase]:AICAR transformylase/IMP cyclohydrolase PurH (only IMP cyclohydrolase domain in Aful):NADPH:quinone reductase and related Zn-dependent oxidoreductases:Putative intracellular protease/amidase:MoxR-like ATPases:Predicted transcriptional regulators:Arabinose efflux permease:Amino acid transport and metabolism:Nucleotide transport and metabolism:Carbohydrate transport and metabolism:Coenzyme transport and metabolism:Transcription:Purine metabolism:Pyruvate metabolism:One carbon pool by folate:Metabolic pathways:Biosynthesis of secondary metabolites:General function prediction only:purH:ocin_ThiF_like:Information storage and processing:Carbohydrate Metabolism:Nucleotide Metabolism:Metabolism of Cofactors and Vitamins:Global:Metabolism:Purines, pyrimidines, nucleosides, and nucleotides:Purine ribonucleotide biosynthesis:Cellular processes:Toxin production and resistance:Metabolism:Metabolism:Poorly characterized" 180 "Energy production and conversion:Lipoate-protein ligase A:Preprotein translocase subunit SecD:Aspartate/tyrosine/aromatic aminotransferase:Nucleoside-diphosphate-sugar epimerases:Zn-dependent hydrolases, including glyoxylases:Putative GTPases (G3E family):Predicted oxidoreductases (related to aryl-alcohol dehydrogenases):Na+/H+ antiporter NhaD and related arsenite permeases:Transcriptional regulator:Cu/Zn superoxide dismutase:Di- and tripeptidases:3-carboxymuconate cyclase:Predicted oxidoreductase:Amino acid transport and metabolism:Carbohydrate transport and metabolism:Coenzyme transport and metabolism:Transcription:Cell wall/membrane/envelope biogenesis:Inorganic ion transport and metabolism:Pentose phosphate pathway:Lysine biosynthesis:Arginine and proline metabolism:Histidine metabolism:beta-Alanine metabolism:Glutathione metabolism:Lipoic acid metabolism:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:Protein export:Bacterial secretion system:General function prediction only:lipoyltrans:2A0604s01:aa-his-dipept:Intracellular trafficking, secretion, and vesicular transport:Metabolism:Global:Membrane Transport:Environmental Information Processing:Folding Sorting and Degradation:Genetic Information Processing:Metabolism of Cofactors and Vitamins:Metabolism of Other Amino Acids:Amino Acid Metabolism:Information storage and processing:Carbohydrate Metabolism:Cellular processes and signaling:Metabolism:Poorly characterized:Protein modification and repair:Protein and peptide secretion and trafficking:Protein fate:Metabolism" 181 "Energy production and conversion:K+ transport systems, NAD-binding component:Zn-dependent alcohol dehydrogenases, class III:UDP-glucose 4-epimerase:Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis/translation initiation factor 2B, gamma/epsilon subunits (eIF-2Bgamma/eIF-2Bepsilon):Uncharacterized conserved protein:Predicted membrane protein:SH3 domain protein:Zinc metalloprotease (elastase):Phage-related protein:Amino acid transport and metabolism:Translation, ribosomal structure and biogenesis:Cell wall/membrane/envelope biogenesis:Inorganic ion transport and metabolism:Glycolysis / Gluconeogenesis:Fatty acid metabolism:Tyrosine metabolism:Starch and sucrose metabolism:Amino sugar and nucleotide sugar metabolism:Chloroalkane and chloroalkene degradation:Naphthalene degradation:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:Function unknown:Signal transduction mechanisms:efflux_EmrB:LPXTG_anchor:tape_meas_TP901:G1P_cyt_trans:docking_ocin:antibiot_sagB:Cellular processes and signaling:Carbohydrate Metabolism:Lipid Metabolism:Amino Acid Metabolism:Xenobiotics Biodegradation and Metabolism:Global:Metabolism:Transport and binding proteins:Other:Mobile and extrachromosomal element functions:Prophage functions:Cell envelope:Other:Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides:Information storage and processing:Metabolism:Metabolism:Poorly characterized" 182 "Energy production and conversion:F0F1-type ATP synthase, beta subunit:F0F1-type ATP synthase, alpha subunit:F0F1-type ATP synthase, gamma subunit:tRNA-(guanine-N1)-methyltransferase:F0F1-type ATP synthase, epsilon subunit (mitochondrial delta subunit):F0F1-type ATP synthase, subunit a:CDP-diglyceride synthetase:Predicted phosphoesterase:F0F1-type ATP synthase, subunit b:F0F1-type ATP synthase, delta subunit (mitochondrial oligomycin sensitivity protein):1-deoxy-D-xylulose 5-phosphate reductoisomerase:RimM protein, required for 16S rRNA processing:DNA polymerase III, alpha subunit (gram-positive type):Lipid transport and metabolism:Translation, ribosomal structure and biogenesis:Replication, recombination and repair:Oxidative phosphorylation:Purine metabolism:Pyrimidine metabolism:Glycerophospholipid metabolism:Terpenoid backbone biosynthesis:Metabolic pathways:Biosynthesis of secondary metabolites:DNA replication:Mismatch repair:Homologous recombination:General function prediction only:yfcE:trmD:Dxr:dnaq:atpA:atpD:ATP_synt_6_or_A:ATP_synt_b:ATP_synt_delta:ATPsyn_F1gamma:ATP_synt_epsi:ATP_synt_c:16S_RimM:Unknown function:Energy Metabolism:Lipid Metabolism:Nucleotide Metabolism:Metabolism of Terpenoids and Polyketides:Genetic Information Processing:Replication and Repair:Global:Metabolism:Energy metabolism:ATP-proton motive force interconversion:DNA metabolism:Degradation of DNA:Transcription:RNA processing:Protein synthesis:tRNA and rRNA base modification:Metabolism:Enzymes of unknown specificity:Biosynthesis of cofactors, prosthetic groups, and carriers:Other:Information storage and processing:Metabolism:Poorly characterized" 183 "Acetyl-CoA acetyltransferase:Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis:Predicted phosphatase/phosphohexomutase:dTDP-glucose pyrophosphorylase:Phosphatidylserine/phosphatidylglycerophosphate/cardiolipin synthases and related enzymes:Uncharacterized conserved protein:Lipid transport and metabolism:Cell wall/membrane/envelope biogenesis:Fatty acid metabolism:Synthesis and degradation of ketone bodies:Valine leucine and isoleucine degradation:Lysine degradation:Benzoate degradation:Tryptophan metabolism:Phosphonate and phosphinate metabolism:Streptomycin biosynthesis:Polyketide sugar unit biosynthesis:Glycerophospholipid metabolism:Pyruvate metabolism:Glyoxylate and dicarboxylate metabolism:Propanoate metabolism:Butanoate metabolism:Carbon fixation pathways in prokaryotes:Terpenoid backbone biosynthesis:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:Two-component system:General function prediction only:Function unknown:phosphonatase:AcCoA-C-Actrans:spore_III_AG:spore_YlmC_YmxH:Other:Fatty acid and phospholipid metabolism:Other:Cellular processes:Sporulation and germination:Cellular processes and signaling:Metabolism:Poorly characterized:Xenobiotics Biodegradation and Metabolism:Biosynthesis of Other Secondary Metabolites:Metabolism:Metabolism of Terpenoids and Polyketides:Metabolism of Other Amino Acids:Amino Acid Metabolism:Lipid Metabolism:Energy Metabolism:Metabolism:Carbohydrate Metabolism:Global:Signal Transduction:Environmental Information Processing:Central intermediary metabolism" 184 "Predicted transcriptional regulators:DNA replication protein:Transcription:Replication, recombination and repair:DnaD_dom:excise:General:Information storage and processing:Unknown function:Prophage functions:Mobile and extrachromosomal element functions" 185 "Amidases related to nicotinamidase:Secondary metabolites biosynthesis, transport and catabolism:tiny_TM_bacill:cognate_SipW:Conserved:Hypothetical proteins:Metabolism" 186 "ABC-type branched-chain amino acid transport systems, ATPase component:Predicted permeases:Sugar (pentulose and hexulose) kinases:Inosine-uridine nucleoside N-ribohydrolase:Histidine ammonia-lyase:Amino acid transport and metabolism:Nucleotide transport and metabolism:Carbohydrate transport and metabolism:Purine metabolism:Histidine metabolism:Glycerolipid metabolism:Nicotinate and nicotinamide metabolism:Nitrogen metabolism:Metabolic pathways:ABC transporters:General function prediction only:hutH:phgtail_TP901_1:Energy metabolism:Amino acids and amines:Mobile and extrachromosomal element functions:Prophage functions:Metabolism:Poorly characterized:Metabolism:Global:Membrane Transport:Environmental Information Processing:Metabolism of Cofactors and Vitamins:Amino Acid Metabolism:Nucleotide Metabolism:Lipid Metabolism:Metabolism:Energy Metabolism" 187 "Energy production and conversion:Nucleoside diphosphate kinase:Translation elongation factor P (EF-P)/translation initiation factor 5A (eIF-5A):Putative translation initiation inhibitor, yjgF family:Deoxyribose-phosphate aldolase:Glycerophosphoryl diester phosphodiesterase:Universal stress protein UspA and related nucleotide-binding proteins:cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases:Small-conductance mechanosensitive channel:Purine-nucleoside phosphorylase:Inorganic pyrophosphatase/exopolyphosphatase:Cold shock proteins:Arginine repressor:Ribosome-associated protein Y (PSrp-1):Acetyltransferases, including N-acetylases of ribosomal proteins:Predicted small molecule binding protein (contains 3H domain):Uncharacterized protein, 4-oxalocrotonate tautomerase homolog:Uncharacterized conserved protein:AT-rich DNA-binding protein:Nitric oxide synthase, oxygenase domain:Membrane protein involved in cytochrome C biogenesis:Amino acid transport and metabolism:Nucleotide transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:Cell wall/membrane/envelope biogenesis:Posttranslational modification, protein turnover, chaperones:Inorganic ion transport and metabolism:Pentose phosphate pathway:Oxidative phosphorylation:Purine metabolism:Pyrimidine metabolism:Arginine and proline metabolism:Tyrosine metabolism:Benzoate degradation:Glycerophospholipid metabolism:Dioxin degradation:Naphthalene degradation:Aminobenzoate degradation:Ethylbenzene degradation:Nicotinate and nicotinamide metabolism:Limonene and pinene degradation:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:General function prediction only:Function unknown:Signal transduction mechanisms:TIGR00004:taut:efp:deoD:deoC:TIGR00266:yfiA:argR_whole:Poorly characterized:Carbohydrate Metabolism:Energy Metabolism:Lipid Metabolism:Nucleotide Metabolism:Amino Acid Metabolism:Metabolism of Cofactors and Vitamins:Metabolism of Terpenoids and Polyketides:Xenobiotics Biodegradation and Metabolism:Global:Metabolism:Energy metabolism:Other:Purines, pyrimidines, nucleosides, and nucleotides:Salvage of nucleosides and nucleotides:Regulatory functions:DNA interactions:Transcription:Degradation of RNA:Protein synthesis:Translation factors:Hypothetical proteins:Conserved:Information storage and processing:Cellular processes and signaling:Metabolism:Metabolism" 188 "Energy production and conversion:Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit:GTPases - translation elongation factors:Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase:Enolase:Translation elongation factors (GTPases):Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component, and related enzymes:Phosphoglyceromutase:Heme/copper-type cytochrome/quinol oxidases, subunit 1:Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit:Phosphoenolpyruvate-protein kinase (PTS system EI component in bacteria):Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes:Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific:Heme/copper-type cytochrome/quinol oxidases, subunit 2:Heme/copper-type cytochrome/quinol oxidase, subunit 3:Phosphotransferase system, HPr-related proteins:Transcriptional regulator, contains sigma factor-related N-terminal domain:Heme/copper-type cytochrome/quinol oxidase, subunit 4:Carbohydrate transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:Glycolysis / Gluconeogenesis:Citrate cycle (TCA cycle):Oxidative phosphorylation:Glycine serine and threonine metabolism:Valine leucine and isoleucine degradation:Valine leucine and isoleucine biosynthesis:Amino sugar and nucleotide sugar metabolism:Pyruvate metabolism:Butanoate metabolism:Methane metabolism:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:Phosphotransferase system (PTS):RNA degradation:small_GTP:EIIB_glc:PTS_HPr_family:eno:pgm_bpd_ind:lipoamide_DH:PTS_I_fam:QOXA:GAPDH-I:QoxB:QoxC:QoxD:PDH_E1_alph_x:Information storage and processing:PTS:Signal transduction:General:Unknown function:Pyruvate dehydrogenase:Glycolysis/gluconeogenesis:Electron transport:Energy metabolism:Metabolism:Global:Membrane Transport:Environmental Information Processing:Metabolism:Folding Sorting and Degradation:Genetic Information Processing:Amino Acid Metabolism:Energy Metabolism:Metabolism:Carbohydrate Metabolism" 189 "Ornithine carbamoyltransferase:Zn-dependent hydrolases, including glyoxylases:Acetyltransferases, including N-acetylases of ribosomal proteins:Beta-lactamase class C and other penicillin binding proteins:Response regulator of citrate/malate metabolism:Amino acid transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:Arginine and proline metabolism:Tyrosine metabolism:Benzoate degradation:Naphthalene degradation:Aminobenzoate degradation:Ethylbenzene degradation:Limonene and pinene degradation:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:General function prediction only:Signal transduction mechanisms:orni_carb_tr:spore_ger_x_C:Defense mechanisms:Cellular processes:Amino Acid Metabolism:Metabolism of Terpenoids and Polyketides:Xenobiotics Biodegradation and Metabolism:Global:Metabolism:Metabolism:Sporulation and germination:Amino acid biosynthesis:Glutamate family:Information storage and processing:Cellular processes and signaling:Metabolism:Poorly characterized" 190 "Energy production and conversion:Uroporphyrinogen-III methylase:Molybdopterin biosynthesis enzyme:Molybdopterin converting factor, large subunit:Cation transport ATPase:Flavodoxin reductases (ferredoxin-NADPH reductases) family 1:Nitrate reductase beta subunit:6Fe-6S prismane cluster-containing protein:Pyruvate-formate lyase-activating enzyme:NAD(P)H-nitrite reductase:Siroheme synthase (precorrin-2 oxidase/ferrochelatase domain):Molybdopterin converting factor, small subunit:Uncharacterized conserved protein:Ferredoxin subunits of nitrite reductase and ring-hydroxylating dioxygenases:Nitrate reductase delta subunit:Nitrate reductase gamma subunit:Nitrate/nitrite transporter:Regulator of cell morphogenesis and NO signaling:Uncharacterized protein conserved in bacteria:Nitrate reductase alpha subunit:Cell cycle control, cell division, chromosome partitioning:Coenzyme transport and metabolism:Posttranslational modification, protein turnover, chaperones:Inorganic ion transport and metabolism:Porphyrin and chlorophyll metabolism:Nitrogen metabolism:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:Two-component system:Sulfur relay system:General function prediction only:Function unknown:molyb_syn:narI:narJ:cobA_cysG_Cterm:cysG_Nterm:ATPase_P-type:narG:narH:moaD:hybrid_clust:nitri_red_nirB:nirD_assim_sml:PFLA:FeS_repair_RIC:Metabolism:Energy Metabolism:Metabolism of Cofactors and Vitamins:Genetic Information Processing:Folding Sorting and Degradation:Environmental Information Processing:Signal Transduction:Global:Metabolism:Central intermediary metabolism:Nitrogen metabolism:Energy metabolism:Amino acids and amines:Anaerobic:Protein fate:Protein folding and stabilization:Protein modification and repair:Biosynthesis of cofactors, prosthetic groups, and carriers:Other:Heme, porphyrin, and cobalamin:Molybdopterin:Cellular processes and signaling:Metabolism:Poorly characterized" 191 "1-acyl-sn-glycerol-3-phosphate acyltransferase:Acyl carrier protein:3-oxoacyl-(acyl-carrier-protein) synthase:(acyl-carrier-protein) S-malonyltransferase:3-oxoacyl-[acyl-carrier-protein] synthase III:Fatty acid/phospholipid biosynthesis enzyme:Biotin carboxyl carrier protein:dsRNA-specific ribonuclease:Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily):Enoyl-[acyl-carrier-protein] reductase (NADH):Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases):Uncharacterized protein conserved in bacteria:Uncharacterized proteins of the AP superfamily:Uncharacterized protein, possibly involved in aromatic compounds catabolism:Predicted acetyltransferase:Fatty acid desaturase:Uncharacterized conserved protein:Lipid transport and metabolism:Transcription:Fatty acid biosynthesis:Bisphenol degradation:Glycerolipid metabolism:Glycerophospholipid metabolism:Pyruvate metabolism:Aminobenzoate degradation:Propanoate metabolism:Biosynthesis of unsaturated fatty acids:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:Two-component system:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:Function unknown:fabD:plsX:acyl_carrier:BCCP:fabH:3oxo_ACP_reduc:RNaseIII:fabF:Environmental Information Processing:Xenobiotics Biodegradation and Metabolism:Lipid Metabolism:RNA processing:Carbohydrate Metabolism:Information storage and processing:Metabolism:Poorly characterized:Transcription:Biosynthesis:Fatty acid and phospholipid metabolism:Metabolism:Global:Metabolism:Signal Transduction" 192 "Nucleotide-binding protein implicated in inhibition of septum formation:Topoisomerase IA:Pseudouridylate synthases, 23S RNA-specific:Lipoprotein signal peptidase:Organic radical activating enzymes:Predicted PP-loop superfamily ATPase:Sulfate permease and related transporters (MFS superfamily):6-pyruvoyl-tetrahydropterin synthase:Enzyme related to GTP cyclohydrolase I:Actin-like ATPase involved in cell morphogenesis:A/G-specific DNA glycosylase:Cell shape-determining protein:Predicted SAM-dependent methyltransferase:Cell shape-determining protein:Uncharacterized protein conserved in bacteria:Predicted membrane protein:Na+/panthothenate symporter:Cell cycle control, cell division, chromosome partitioning:Coenzyme transport and metabolism:Translation, ribosomal structure and biogenesis:Replication, recombination and repair:Cell wall/membrane/envelope biogenesis:Posttranslational modification, protein turnover, chaperones:Inorganic ion transport and metabolism:Folate biosynthesis:Metabolic pathways:Protein export:Base excision repair:General function prediction only:Function unknown:rluA_subfam:lspA:maf:mreC:TIGR00364:YbgI_SA1388:sss:mreB:topA_bact:mutY:QueF-II:Bsubt_queE:queuosine_QueD:shape_MreD:Intracellular trafficking, secretion, and vesicular transport:Unknown function:Metabolism of Cofactors and Vitamins:Genetic Information Processing:Folding Sorting and Degradation:Replication and Repair:Global:Metabolism:DNA metabolism:DNA replication, recombination, and repair:Protein synthesis:tRNA and rRNA base modification:Protein fate:Protein and peptide secretion and trafficking:Transport and binding proteins:Cations and iron carrying compounds:Cellular processes:Cell division:Metabolism:General:Cell envelope:Biosynthesis and degradation of murein sacculus and peptidoglycan:Information storage and processing:Cellular processes and signaling:Metabolism:Poorly characterized" 193 "Mismatch repair ATPase (MutS family):DNA mismatch repair enzyme (predicted ATPase):ATPase involved in DNA repair:DNA repair exonuclease:ATPase components of ABC transporters with duplicated ATPase domains:Superfamily II DNA/RNA helicases, SNF2 family:MoxR-like ATPases:Cell division protein FtsI/penicillin-binding protein 2:dTDP-4-dehydrorhamnose reductase:ABC-type multidrug transport system, ATPase component:Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs:Transcriptional regulator:Predicted HD superfamily hydrolase:Acetyltransferases, including N-acetylases of ribosomal proteins:DNA segregation ATPase FtsK/SpoIIIE and related proteins:Phosphate starvation-inducible protein PhoH, predicted ATPase:3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases:Sporulation protein and related proteins:Signal transduction histidine kinase involved in nitrogen fixation and metabolism regulation:Cell cycle control, cell division, chromosome partitioning:Amino acid transport and metabolism:Lipid transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:Replication, recombination and repair:Cell wall/membrane/envelope biogenesis:Valine leucine and isoleucine degradation:Tyrosine metabolism:Benzoate degradation:Streptomycin biosynthesis:Polyketide sugar unit biosynthesis:Naphthalene degradation:Aminobenzoate degradation:Ethylbenzene degradation:Limonene and pinene degradation:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:ABC transporters:Two-component system:Mismatch repair:General function prediction only:Signal transduction mechanisms:lytR_cpsA_psr:mutl:sbcd:mutS1:rmlD:SpoIID_LytB:Defense mechanisms:Cell envelope:General:Unknown function:DNA replication, recombination, and repair:DNA metabolism:Other:Regulatory functions:Metabolism:Metabolism:Global:Signal Transduction:Membrane Transport:Environmental Information Processing:Replication and Repair:Genetic Information Processing:Xenobiotics Biodegradation and Metabolism:Biosynthesis of Other Secondary Metabolites:Metabolism of Terpenoids and Polyketides:Poorly characterized:Amino Acid Metabolism:Metabolism:Cellular processes and signaling:Information storage and processing:Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides" 194 "Xaa-Pro aminopeptidase:Methylated DNA-protein cysteine methyltransferase:Fe2+ transport system protein B:ATPases involved in chromosome partitioning:Zn-dependent hydrolases, including glyoxylases:Methionine synthase II (cobalamin-independent):Alanine dehydrogenase:Cellulase M and related proteins:Uncharacterized conserved protein:Fe2+ transport system protein A:Enterochelin esterase and related enzymes:Predicted membrane protein:Predicted ABC-type exoprotein transport system, permease component:Site-specific recombinase XerD:Cell cycle control, cell division, chromosome partitioning:Amino acid transport and metabolism:Carbohydrate transport and metabolism:Replication, recombination and repair:Inorganic ion transport and metabolism:Alanine aspartate and glutamate metabolism:Cysteine and methionine metabolism:Taurine and hypotaurine metabolism:Metabolic pathways:Biosynthesis of secondary metabolites:General function prediction only:Function unknown:alaDH:ogt:met_syn_B12ind:Intracellular trafficking, secretion, and vesicular transport:Cellular processes and signaling:Information storage and processing:Aspartate family:Amino acid biosynthesis:DNA replication, recombination, and repair:DNA metabolism:Amino acids and amines:Energy metabolism:Metabolism:Metabolism:Global:Metabolism of Other Amino Acids:Amino Acid Metabolism:Poorly characterized:Metabolism" 195 "Molybdopterin biosynthesis enzyme:NTP pyrophosphohydrolases including oxidative damage repair enzymes:H+/gluconate symporter and related permeases:Arabinose efflux permease:Uncharacterized protein conserved in bacteria:Lyzozyme M1 (1,4-beta-N-acetylmuramidase):Amino acid transport and metabolism:Carbohydrate transport and metabolism:Coenzyme transport and metabolism:Replication, recombination and repair:Cell wall/membrane/envelope biogenesis:General function prediction only:Function unknown:molyb_syn:LPXTG_anchor:Cellular processes and signaling:Poorly characterized:Other:Cell envelope:Information storage and processing:Metabolism" 196 "Energy production and conversion:Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit:Mannose-6-phosphate isomerase:Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit:ABC-type antimicrobial peptide transport system, ATPase component:Predicted membrane protein:Transposase and inactivated derivatives:Uncharacterized conserved protein:Carbohydrate transport and metabolism:Replication, recombination and repair:Glycolysis / Gluconeogenesis:Citrate cycle (TCA cycle):Valine leucine and isoleucine biosynthesis:Bisphenol degradation:Pyruvate metabolism:Polycyclic aromatic hydrocarbon degradation:Aminobenzoate degradation:Butanoate metabolism:Limonene and pinene degradation:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:Function unknown:Defense mechanisms:Information storage and processing:Metabolism:Metabolism:Global:Xenobiotics Biodegradation and Metabolism:Metabolism of Terpenoids and Polyketides:Amino Acid Metabolism:Metabolism:Carbohydrate Metabolism:Poorly characterized:Cellular processes and signaling" 197 "Energy production and conversion:7-keto-8-aminopelargonate synthetase and related enzymes:Nucleoside-diphosphate-sugar epimerases:DNA polymerase sliding clamp subunit (PCNA homolog):NADPH:quinone reductase and related Zn-dependent oxidoreductases:Branched-chain amino acid permeases:Putative effector of murein hydrolase LrgA:Na+/H+ antiporter:Nucleoside permease:Rhodanese-related sulfurtransferase:Amino acid transport and metabolism:Nucleotide transport and metabolism:Carbohydrate transport and metabolism:Coenzyme transport and metabolism:Replication, recombination and repair:Cell wall/membrane/envelope biogenesis:Inorganic ion transport and metabolism:Glycolysis / Gluconeogenesis:Fatty acid metabolism:Purine metabolism:Pyrimidine metabolism:Glycine serine and threonine metabolism:Cysteine and methionine metabolism:Tyrosine metabolism:Chloroalkane and chloroalkene degradation:Naphthalene degradation:Methane metabolism:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:Two-component system:DNA replication:Mismatch repair:Homologous recombination:Sulfur relay system:General function prediction only:dnan:livcs:nupC:antiport_nhaC:gly_Cac_T_rel:oxido_YhdH:Environmental Information Processing:Replication and Repair:Folding Sorting and Degradation:Genetic Information Processing:Metabolism:Xenobiotics Biodegradation and Metabolism:Amino Acid Metabolism:Nucleotide Metabolism:Lipid Metabolism:Energy Metabolism:Carbohydrate Metabolism:Global:Metabolism:DNA metabolism:DNA replication, recombination, and repair:Transport and binding proteins:Amino acids, peptides and amines:Cations and iron carrying compounds:Nucleosides, purines and pyrimidines:Unknown function:Enzymes of unknown specificity:Information storage and processing:Cellular processes and signaling:Metabolism:Poorly characterized:Signal Transduction" 198 "Energy production and conversion:Lipoate-protein ligase A:Phosphotransacetylase:Predicted Fe-S oxidoreductases:Hypoxanthine-guanine phosphoribosyltransferase:Predicted transcriptional regulators:Predicted permeases:Protoporphyrinogen oxidase:Uncharacterized protein required for cytochrome oxidase assembly:Uncharacterized protein SCO1/SenC/PrrC, involved in biogenesis of respiratory and photosynthetic systems:Predicted membrane protein:Uncharacterized conserved protein:Nucleotide transport and metabolism:Coenzyme transport and metabolism:Transcription:Posttranslational modification, protein turnover, chaperones:Oxidative phosphorylation:Purine metabolism:Taurine and hypotaurine metabolism:Pyruvate metabolism:Propanoate metabolism:Methane metabolism:Carbon fixation pathways in prokaryotes:Porphyrin and chlorophyll metabolism:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:Two-component system:General function prediction only:Function unknown:proto_IX_ox:pta:HGPRTase:Cellular processes and signaling:Carbohydrate Metabolism:Energy Metabolism:Nucleotide Metabolism:Metabolism of Other Amino Acids:Metabolism of Cofactors and Vitamins:Environmental Information Processing:Signal Transduction:Global:Metabolism:Energy metabolism:Fermentation:Purines, pyrimidines, nucleosides, and nucleotides:Salvage of nucleosides and nucleotides:Biosynthesis of cofactors, prosthetic groups, and carriers:Heme, porphyrin, and cobalamin:Information storage and processing:Metabolism:Metabolism:Poorly characterized" 199 "Energy production and conversion:Cytidine deaminase:Predicted divalent heavy-metal cations transporter:FOG: CBS domain:Glycerol uptake facilitator and related permeases (Major Intrinsic Protein Family):Glycerophosphoryl diester phosphodiesterase:ABC-type nitrate/sulfonate/bicarbonate transport system, permease component:Amino acid permeases:Amino acid transporters:Sugar (pentulose and hexulose) kinases:Ribose/xylose/arabinose/galactoside ABC-type transport systems, permease components:Flagellar motor component:Na+/H+-dicarboxylate symporters:Putative effector of murein hydrolase:Flagellar motor protein:Putative effector of murein hydrolase LrgA:Phosphotransferase system cellobiose-specific component IIB:Phosphotransferase system cellobiose-specific component IIC:Na+/H+ antiporter:Transcriptional regulators:Phosphotransferase system IIA components:Methylase involved in ubiquinone/menaquinone biosynthesis:Dihydroxyacetone kinase:Transcriptional activator of acetoin/glycerol metabolism:ABC-type oligopeptide transport system, periplasmic component:Predicted membrane protein:Response regulator of citrate/malate metabolism:Predicted permease, DMT superfamily:Predicted metal-dependent enzyme of the double-stranded beta helix superfamily:Amino acid transport and metabolism:Nucleotide transport and metabolism:Carbohydrate transport and metabolism:Coenzyme transport and metabolism:Transcription:Cell wall/membrane/envelope biogenesis:Cell motility:Inorganic ion transport and metabolism:Glycolysis / Gluconeogenesis:Pyrimidine metabolism:Histidine metabolism:Tyrosine metabolism:Selenocompound metabolism:Starch and sucrose metabolism:Amino sugar and nucleotide sugar metabolism:Glycerolipid metabolism:Glycerophospholipid metabolism:Polycyclic aromatic hydrocarbon degradation:Methane metabolism:Metabolic pathways:Microbial metabolism in diverse environments:ABC transporters:Two-component system:Bacterial chemotaxis:Flagellar assembly:Phosphotransferase system (PTS):Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:Function unknown:Signal transduction mechanisms:lacE:PTBA:pts-lac:MIP:antiport_nhaC:cyt_deam_tetra:dhaK1b:dhaK1:Transport and binding proteins:Salvage of nucleosides and nucleotides:Purines, pyrimidines, nucleosides, and nucleotides:Information storage and processing:Cellular processes and signaling:Metabolism:Poorly characterized:Metabolism:Global:Cell Motility:Cellular Processes:Signal Transduction:Metabolism:Membrane Transport:Environmental Information Processing:Xenobiotics Biodegradation and Metabolism:Metabolism of Other Amino Acids:Amino Acid Metabolism:Nucleotide Metabolism:Lipid Metabolism:Energy Metabolism:Signal transduction:Carbohydrate Metabolism:PTS:Cations and iron carrying compounds:Unknown substrate" 200 "Energy production and conversion:Fructose-2,6-bisphosphatase:Pyruvate kinase:Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily):NAD-dependent aldehyde dehydrogenases:ABC-type dipeptide/oligopeptide/nickel transport systems, permease components:Transcriptional regulators of sugar metabolism:Predicted acyl esterases:Amino acid transport and metabolism:Carbohydrate transport and metabolism:Transcription:Inorganic ion transport and metabolism:Glycolysis / Gluconeogenesis:Purine metabolism:Alanine aspartate and glutamate metabolism:Tyrosine metabolism:Benzoate degradation:Pyruvate metabolism:Naphthalene degradation:Aminobenzoate degradation:Ethylbenzene degradation:Butanoate metabolism:Methane metabolism:Limonene and pinene degradation:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:ABC transporters:General function prediction only:pyruv_kin:SSADH:Metabolism:Poorly characterized:Metabolism:Metabolism:Global:Membrane Transport:Environmental Information Processing:Xenobiotics Biodegradation and Metabolism:Metabolism of Terpenoids and Polyketides:Amino Acid Metabolism:Nucleotide Metabolism:Energy Metabolism:Carbohydrate Metabolism:Central intermediary metabolism:Other:Energy metabolism:Glycolysis/gluconeogenesis:Information storage and processing" 201 "Energy production and conversion:Protein chain release factor A:Malic enzyme:Short-chain dehydrogenases of various substrate specificities:Preprotein translocase subunit SecD:Glycosyltransferases involved in cell wall biogenesis:DNA polymerase sliding clamp subunit (PCNA homolog):ABC-type Fe3+-hydroxamate transport system, periplasmic component:Predicted transcriptional regulators:Acetyl-CoA carboxylase beta subunit:Acetyl-CoA carboxylase alpha subunit:4-diphosphocytidyl-2-methyl-D-erithritol synthase:1,4-dihydroxy-2-naphthoate octaprenyltransferase:Predicted membrane protein involved in D-alanine export:Predicted permease:Uncharacterized protein with SCP/PR1 domains:Arabinose efflux permease:Uncharacterized conserved protein:Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein):Predicted membrane protein:Carbohydrate transport and metabolism:Coenzyme transport and metabolism:Lipid transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:Replication, recombination and repair:Cell wall/membrane/envelope biogenesis:Inorganic ion transport and metabolism:Fatty acid biosynthesis:Ubiquinone and other terpenoid-quinone biosynthesis:Purine metabolism:Pyrimidine metabolism:D-Alanine metabolism:Pyruvate metabolism:Propanoate metabolism:Carbon fixation pathways in prokaryotes:Terpenoid backbone biosynthesis:Metabolic pathways:Biosynthesis of secondary metabolites:ABC transporters:Two-component system:DNA replication:Protein export:Bacterial secretion system:Mismatch repair:Homologous recombination:General function prediction only:Function unknown:prfB:TIGR00374:ispD:accA:accD:dnan:efflux_EmrB:menA:2A0604s01:dltC:spore_YkwD:LTA_dltB:LTA_DltD:Intracellular trafficking, secretion, and vesicular transport:Menaquinone and ubiquinone:Carbohydrate Metabolism:Energy Metabolism:Lipid Metabolism:Nucleotide Metabolism:Metabolism of Other Amino Acids:Metabolism of Cofactors and Vitamins:Metabolism of Terpenoids and Polyketides:Genetic Information Processing:Folding Sorting and Degradation:Replication and Repair:Environmental Information Processing:Membrane Transport:Signal Transduction:Global:Metabolism:Fatty acid and phospholipid metabolism:Biosynthesis:DNA metabolism:DNA replication, recombination, and repair:Protein synthesis:Translation factors:Protein fate:Protein and peptide secretion and trafficking:Transport and binding proteins:Other:Hypothetical proteins:Conserved:Biosynthesis of cofactors, prosthetic groups, and carriers:Other:Metabolism:Cell envelope:Biosynthesis and degradation of murein sacculus and peptidoglycan:Information storage and processing:Cellular processes and signaling:Metabolism:Poorly characterized" 202 "Energy production and conversion:Dethiobiotin synthetase:7-keto-8-aminopelargonate synthetase and related enzymes:Adenosylmethionine-8-amino-7-oxononanoate aminotransferase:Dihydrodipicolinate synthase/N-acetylneuraminate lyase:Thiamine monophosphate synthase:Biotin synthase and related enzymes:Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily):Predicted UDP-glucose 6-dehydrogenase:NAD-dependent aldehyde dehydrogenases:Predicted glycosyltransferases:Phytoene dehydrogenase and related proteins:FOG: GAF domain:Predicted membrane protein:Acetyl/propionyl-CoA carboxylase, alpha subunit:Spore coat assembly protein:Amino acid transport and metabolism:Coenzyme transport and metabolism:Lipid transport and metabolism:Cell wall/membrane/envelope biogenesis:Glycolysis / Gluconeogenesis:Pentose and glucuronate interconversions:Ascorbate and aldarate metabolism:Fatty acid biosynthesis:Fatty acid metabolism:Valine leucine and isoleucine degradation:Lysine biosynthesis:Lysine degradation:Arginine and proline metabolism:Histidine metabolism:Tyrosine metabolism:Benzoate degradation:Tryptophan metabolism:beta-Alanine metabolism:Starch and sucrose metabolism:Amino sugar and nucleotide sugar metabolism:Glycerolipid metabolism:Pyruvate metabolism:Chloroalkane and chloroalkene degradation:Naphthalene degradation:Aminobenzoate degradation:Propanoate metabolism:Ethylbenzene degradation:Carbon fixation pathways in prokaryotes:Biotin metabolism:Limonene and pinene degradation:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:Function unknown:Signal transduction mechanisms:bioD:bioB:bioA:dapA:bioF:GPR:NDP-sugDHase:Cellular processes and signaling:Biotin:Biosynthesis of cofactors, prosthetic groups, and carriers:Aspartate family:Amino acid biosynthesis:Sporulation and germination:Cellular processes:Metabolism:Global:Xenobiotics Biodegradation and Metabolism:Metabolism of Terpenoids and Polyketides:Metabolism of Cofactors and Vitamins:Metabolism of Other Amino Acids:Amino Acid Metabolism:Lipid Metabolism:Metabolism:Energy Metabolism:Poorly characterized:Carbohydrate Metabolism:Metabolism" 203 "Histidinol phosphatase and related phosphatases:Putative translation initiation inhibitor, yjgF family:Acetyltransferases:Enoyl-CoA hydratase/carnithine racemase:Oligoendopeptidase F:DNA-directed RNA polymerase specialized sigma subunit:Amidases related to nicotinamidase:Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor):Predicted transcriptional regulators:Acetyltransferases, including N-acetylases of ribosomal proteins:Anti-sigma regulatory factor (Ser/Thr protein kinase):Predicted Zn-dependent hydrolases of the beta-lactamase fold:Zn-dependent carboxypeptidase:Uncharacterized conserved protein:Gluconolactonase:Predicted acetyltransferase:DNA gyrase inhibitor:Amino acid transport and metabolism:Carbohydrate transport and metabolism:Lipid transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:Replication, recombination and repair:Fatty acid metabolism:Valine leucine and isoleucine degradation:Geraniol degradation:Lysine degradation:Benzoate degradation:Tryptophan metabolism:beta-Alanine metabolism:Aminobenzoate degradation:Propanoate metabolism:Butanoate metabolism:Limonene and pinene degradation:Biosynthesis of siderophore group nonribosomal peptides:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:RNA polymerase:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:Function unknown:Signal transduction mechanisms:ant_ant_sig:Histidinol-ppas:spIIAB:M3_not_pepF:spore_sigF:Transcription:Genetic Information Processing:Xenobiotics Biodegradation and Metabolism:Metabolism of Terpenoids and Polyketides:Metabolism of Other Amino Acids:Amino Acid Metabolism:Lipid Metabolism:Cellular processes and signaling:Carbohydrate Metabolism:Metabolism:Poorly characterized:Information storage and processing:Sporulation and germination:Cellular processes:Protein interactions:Regulatory functions:Metabolism:Metabolism:Global" 204 "Energy production and conversion:Serine-pyruvate aminotransferase/archaeal aspartate aminotransferase:Membrane protein TerC, possibly involved in tellurium resistance:UDP-glucose 4-epimerase:ABC-type multidrug transport system, ATPase component:Threonine dehydratase:Glycosyltransferases, probably involved in cell wall biogenesis:Transcriptional regulators:D-alanyl-D-alanine carboxypeptidase:Na+/H+ antiporter:Uncharacterized conserved protein:Permeases of the major facilitator superfamily:Predicted membrane protein:Predicted membrane protein:Membrane protein involved in cytochrome C biogenesis:Amino acid transport and metabolism:Transcription:Cell wall/membrane/envelope biogenesis:Posttranslational modification, protein turnover, chaperones:Inorganic ion transport and metabolism:Fructose and mannose metabolism:Galactose metabolism:Glycine serine and threonine metabolism:Valine leucine and isoleucine biosynthesis:Amino sugar and nucleotide sugar metabolism:Methane metabolism:Metabolic pathways:Biosynthesis of secondary metabolites:General function prediction only:Function unknown:antiport_nhaC:ilvA_1Cterm:galE:R_switched_YkoY:thiopep_ocin:Defense mechanisms:Transport and binding proteins:Sugars:Energy metabolism:Metabolism:Metabolism:Global:Amino Acid Metabolism:Energy Metabolism:Information storage and processing:Carbohydrate Metabolism:Cellular processes and signaling:Metabolism:Poorly characterized:Pyruvate family:Amino acid biosynthesis:Toxin production and resistance:Cellular processes:Cations and iron carrying compounds" 205 "Energy production and conversion:Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit:Phosphotransacetylase:Glutamate dehydrogenase/leucine dehydrogenase:Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component, and related enzymes:Methionine synthase I (cobalamin-dependent), methyltransferase domain:Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit:Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes:Type II secretory pathway, component PulF:Type II secretory pathway, ATPase PulE/Tfp pilus assembly pathway, ATPase PilB:Arabinose efflux permease:Butyrate kinase:Competence protein ComGC:Amino acid transport and metabolism:Carbohydrate transport and metabolism:Cell motility:Glycolysis / Gluconeogenesis:Citrate cycle (TCA cycle):Glycine serine and threonine metabolism:Cysteine and methionine metabolism:Valine leucine and isoleucine degradation:Valine leucine and isoleucine biosynthesis:Pyruvate metabolism:Butanoate metabolism:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:2A0309:lipoamide_DH:phage_arpU:IV_pilin_GFxxxE:P_butyryltrans:butyr_kinase:spore_ger_x_C:Intracellular trafficking, secretion, and vesicular transport:Sporulation and germination:Carbohydrate Metabolism:Amino Acid Metabolism:Global:Metabolism:Energy metabolism:Fermentation:Regulatory functions:DNA interactions:Protein fate:Protein and peptide secretion and trafficking:Transport and binding proteins:Amino acids, peptides and amines:Cellular processes:Metabolism:Cellular processes and signaling:Metabolism" 206 "Energy production and conversion:ABC-type branched-chain amino acid transport systems, ATPase component:Isocitrate/isopropylmalate dehydrogenase:Branched-chain amino acid ABC-type transport system, permease components:Permeases of the drug/metabolite transporter (DMT) superfamily:Amino acid transport and metabolism:Carbohydrate transport and metabolism:Valine leucine and isoleucine biosynthesis:Metabolic pathways:Biosynthesis of secondary metabolites:ABC transporters:General function prediction only:leuB:Amino acid biosynthesis:Amino Acid Metabolism:Environmental Information Processing:Membrane Transport:Global:Metabolism:Metabolism:Pyruvate family:Metabolism:Poorly characterized" 207 "Ribosomal protein L13:Ribosomal protein S9:Ribosomal protein S15P/S13E:Ribosomal protein L28:Ribosomal protein S16:Ribosomal protein S18:Ribosomal protein S20:Translation initiation factor 3 (IF-3):Ribosomal protein L35:Ribosomal protein L20:Ribosomal protein L19:Uncharacterized conserved protein:Predicted RNA-binding protein (contains KH domain):Uncharacterized protein conserved in bacteria:Translation, ribosomal structure and biogenesis:Ribosome:General function prediction only:Function unknown:rpmI_bact:S16:L28:S20:S21p:S18:infC:S15_bact:rplS_bact:rplT_bact:rplM_bact:Poorly characterized:Translation:Protein synthesis:Ribosomal proteins: synthesis and modification:Translation factors:Information storage and processing:Genetic Information Processing" 208 "Deoxyribodipyrimidine photolyase:SAM-dependent methyltransferases:Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily):1,4-dihydroxy-2-naphthoate octaprenyltransferase:Predicted transcriptional regulators:Lysophospholipase L1 and related esterases:DNA-binding HTH domain-containing proteins:Predicted permeases:Predicted ABC-type exoprotein transport system, permease component:Uncharacterized conserved protein:Amino acid transport and metabolism:Coenzyme transport and metabolism:Transcription:Replication, recombination and repair:Ubiquinone and other terpenoid-quinone biosynthesis:Metabolic pathways:Biosynthesis of secondary metabolites:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:Function unknown:rarD:menA:Intracellular trafficking, secretion, and vesicular transport:Global:Information storage and processing:Metabolism of Cofactors and Vitamins:Cellular processes and signaling:Metabolism:Poorly characterized:Metabolism:Menaquinone and ubiquinone:Biosynthesis of cofactors, prosthetic groups, and carriers:Unknown substrate:Transport and binding proteins:Metabolism" 209 "Energy production and conversion:Methionyl-tRNA formyltransferase:NTP pyrophosphohydrolases including oxidative damage repair enzymes:ABC-type dipeptide/oligopeptide/nickel transport systems, permease components:5'-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases:ABC-type Na+ efflux pump, permease component:Beta-lactamase class C and other penicillin binding proteins:Lysophospholipase:Sugar phosphate permease:Predicted membrane protein:Peptidylarginine deiminase and related enzymes:Predicted aminoglycoside phosphotransferase:Zinc metalloprotease (elastase):Uncharacterized conserved protein:Uncharacterized protein involved in tellurite resistance:Phage terminase-like protein, large subunit:Amino acid transport and metabolism:Nucleotide transport and metabolism:Carbohydrate transport and metabolism:Lipid transport and metabolism:Translation, ribosomal structure and biogenesis:Replication, recombination and repair:Inorganic ion transport and metabolism:Purine metabolism:Pyrimidine metabolism:Glycerophospholipid metabolism:One carbon pool by folate:Aminoacyl-tRNA biosynthesis:ABC transporters:General function prediction only:Function unknown:Defense mechanisms:Information storage and processing:Membrane Transport:Environmental Information Processing:Metabolism:Translation:Genetic Information Processing:Metabolism of Cofactors and Vitamins:Nucleotide Metabolism:Lipid Metabolism:Poorly characterized:Metabolism:Cellular processes and signaling" 210 "Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily):Cell division protein FtsI/penicillin-binding protein 2:Transcriptional regulator:D-alanyl-D-alanine carboxypeptidase:Arabinose efflux permease:Uncharacterized protein conserved in bacteria:Uncharacterized protein conserved in bacteria:Carbohydrate transport and metabolism:Transcription:Cell wall/membrane/envelope biogenesis:Arginine and proline metabolism:Metabolic pathways:General function prediction only:Function unknown:spore_II_P:Poorly characterized:Amino Acid Metabolism:Global:Metabolism:Cellular processes:Sporulation and germination:Information storage and processing:Cellular processes and signaling:Metabolism:Metabolism" 211 "Lactoylglutathione lyase and related lyases:Predicted phosphatases:Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases):Acetyltransferases, including N-acetylases of ribosomal proteins:Uncharacterized protein conserved in bacteria:Peptidase E:Gluconolactonase:Predicted acetyltransferase:Conserved protein containing a Zn-ribbon-like motif, possibly RNA-binding:Amino acid transport and metabolism:Carbohydrate transport and metabolism:Lipid transport and metabolism:Translation, ribosomal structure and biogenesis:Synthesis and degradation of ketone bodies:Pyruvate metabolism:Butanoate metabolism:Metabolic pathways:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:Function unknown:HAD-SF-IA-v1:PHB_DH:Information storage and processing:Carbohydrate Metabolism:Metabolism:Poorly characterized:Metabolism:Enzymes of unknown specificity:Unknown function:Metabolism:Global:Lipid Metabolism" 212 "Energy production and conversion:Dihydrofolate reductase:Universal stress protein UspA and related nucleotide-binding proteins:Signal transduction histidine kinase:UDP-N-acetyl-D-mannosaminuronate dehydrogenase:NAD-dependent aldehyde dehydrogenases:Phosphotransferase system cellobiose-specific component IIA:Acyl-CoA dehydrogenases:3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases:Uncharacterized protein conserved in bacteria:Site-specific recombinase XerD:Carbohydrate transport and metabolism:Coenzyme transport and metabolism:Lipid transport and metabolism:Replication, recombination and repair:Cell wall/membrane/envelope biogenesis:Fructose and mannose metabolism:Valine leucine and isoleucine degradation:Geraniol degradation:Bisphenol degradation:Inositol phosphate metabolism:Chloroalkane and chloroalkene degradation:Naphthalene degradation:Propanoate metabolism:Butanoate metabolism:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:Phosphotransferase system (PTS):Function unknown:Signal transduction mechanisms:MMSDH:spore_IV_A:NDP-sugDHase:Metabolism:Carbohydrate Metabolism:Amino Acid Metabolism:Metabolism of Terpenoids and Polyketides:Xenobiotics Biodegradation and Metabolism:Environmental Information Processing:Membrane Transport:Global:Metabolism:Energy metabolism:Amino acids and amines:Cellular processes:Sporulation and germination:Information storage and processing:Cellular processes and signaling:Metabolism:Poorly characterized" 213 "Energy production and conversion:Superfamily II DNA and RNA helicases:Glycerophosphoryl diester phosphodiesterase:Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily):Signal transduction histidine kinase:Spermidine/putrescine-binding periplasmic protein:Amino acid permeases:Methyl-accepting chemotaxis protein:Non-ribosomal peptide synthetase modules and related proteins:Branched-chain amino acid permeases:Na+/alanine symporter:ABC-type multidrug transport system, ATPase component:Uncharacterized protein conserved in bacteria:Predicted membrane protein:Arabinose efflux permease:Uncharacterized protein conserved in bacteria:Sortase (surface protein transpeptidase):Amino acid transport and metabolism:Carbohydrate transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:Replication, recombination and repair:Cell wall/membrane/envelope biogenesis:Cell motility:Glycerophospholipid metabolism:ABC transporters:Two-component system:Bacterial chemotaxis:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:Function unknown:Signal transduction mechanisms:DegV:livcs:agcS:sortase_fam:LPXTG_anchor:AA-adenyl-dom:exospor_lead:Defense mechanisms:Information storage and processing:Other:Cell envelope:General:Unknown function:Sporulation and germination:Cellular processes:Amino acids, peptides and amines:Transport and binding proteins:Protein and peptide secretion and trafficking:Protein fate:Metabolism:Cell Motility:Cellular Processes:Signal Transduction:Membrane Transport:Environmental Information Processing:Lipid Metabolism:Poorly characterized:Metabolism:Cellular processes and signaling" 214 "Ammonia permease:Predicted Co/Zn/Cd cation transporters:Zn-dependent hydrolases, including glyoxylases:NTP pyrophosphohydrolases including oxidative damage repair enzymes:Predicted transcriptional regulators:Chemotaxis protein histidine kinase and related kinases:Predicted permeases:5'-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases:Amino acid permeases:Methyl-accepting chemotaxis protein:N-acetylmuramoyl-L-alanine amidase:UDP-glucose 4-epimerase:Uncharacterized conserved protein:Flagellin-specific chaperone FliS:Transcriptional regulators:Predicted membrane protein:Uncharacterized conserved protein:Predicted membrane protein:Uncharacterized conserved protein:Amino acid transport and metabolism:Nucleotide transport and metabolism:Transcription:Replication, recombination and repair:Cell wall/membrane/envelope biogenesis:Cell motility:Posttranslational modification, protein turnover, chaperones:Inorganic ion transport and metabolism:Galactose metabolism:Purine metabolism:Pyrimidine metabolism:Amino sugar and nucleotide sugar metabolism:Nicotinate and nicotinamide metabolism:Metabolic pathways:Biosynthesis of secondary metabolites:Two-component system:Bacterial chemotaxis:Flagellar assembly:General function prediction only:Function unknown:Signal transduction mechanisms:amt:galE:CDF:Intracellular trafficking, secretion, and vesicular transport:Metabolism:Metabolism:Global:Poorly characterized:Metabolism:Cell Motility:Cellular Processes:Cellular processes and signaling:Signal Transduction:Environmental Information Processing:Information storage and processing:Metabolism of Cofactors and Vitamins:Cations and iron carrying compounds:Transport and binding proteins:Nucleotide Metabolism:Sugars:Energy metabolism:Carbohydrate Metabolism" 215 "Cystathionine beta-lyases/cystathionine gamma-synthases:ABC-type metal ion transport system, ATPase component:ABC-type metal ion transport system, periplasmic component/surface antigen:Uncharacterized conserved protein, contains double-stranded beta-helix domain:Ribulose 1,5-bisphosphate carboxylase, large subunit:ABC-type metal ion transport system, permease component:O-acetylhomoserine sulfhydrylase:ABC-type oligopeptide transport system, periplasmic component:Uncharacterized conserved protein, possibly involved in methylthioadenosine recycling:Amino acid transport and metabolism:Carbohydrate transport and metabolism:Inorganic ion transport and metabolism:Cysteine and methionine metabolism:Selenocompound metabolism:Nitrogen metabolism:Sulfur metabolism:Metabolic pathways:Biosynthesis of secondary metabolites:ABC transporters:Function unknown:OAH_OAS_sulfhy:HAD-SF-IB:salvage_mtnW:Sulfur metabolism:Energy Metabolism:Amino Acid Metabolism:Metabolism of Other Amino Acids:Environmental Information Processing:Membrane Transport:Global:Metabolism:Central intermediary metabolism:Metabolism:Unknown function:Enzymes of unknown specificity:Amino acid biosynthesis:Serine family:Metabolism:Poorly characterized" 216 "Arginase/agmatinase/formimionoglutamate hydrolase, arginase family:Short-chain dehydrogenases of various substrate specificities:SAM-dependent methyltransferases:Thioredoxin-like proteins and domains:Predicted transcriptional regulators:Uncharacterized protein, involved in the regulation of septum location:Predicted Zn-dependent hydrolases of the beta-lactamase fold:Response regulator of the LytR/AlgR family:Predicted nucleotidyltransferase:Uncharacterized protein conserved in bacteria:Uncharacterized protein containing a divergent version of the methyl-accepting chemotaxis-like domain:Uncharacterized conserved protein:Amino acid transport and metabolism:Transcription:Cell wall/membrane/envelope biogenesis:Posttranslational modification, protein turnover, chaperones:Fatty acid biosynthesis:Arginine and proline metabolism:Biosynthesis of unsaturated fatty acids:Metabolic pathways:Biosynthesis of secondary metabolites:Two-component system:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:Function unknown:Signal transduction mechanisms:rocF_arginase:B_thiol_YtxJ:Poorly characterized:Lipid Metabolism:Amino Acid Metabolism:Environmental Information Processing:Signal Transduction:Global:Metabolism:Unknown function:Enzymes of unknown specificity:Information storage and processing:Cellular processes and signaling:Metabolism:Metabolism" 217 "Methionine aminopeptidase:Nuclease subunit of the excinuclease complex:Acetyltransferases:SAM-dependent methyltransferases:ABC-type dipeptide/oligopeptide/nickel transport systems, permease components:cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases:Permeases of the drug/metabolite transporter (DMT) superfamily:ABC-type multidrug transport system, ATPase and permease components:ABC-type dipeptide/oligopeptide/nickel transport systems, permease components:Putative threonine efflux protein:DnaK suppressor protein:D-alanyl-D-alanine carboxypeptidase:Uncharacterized bacitracin resistance protein:Putative multicopper oxidases:Predicted transcriptional regulator:Leucine-rich repeat (LRR) protein:Amino acid transport and metabolism:Carbohydrate transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:Replication, recombination and repair:Cell wall/membrane/envelope biogenesis:Inorganic ion transport and metabolism:Alanine aspartate and glutamate metabolism:Peptidoglycan biosynthesis:Nitrogen metabolism:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:ABC transporters:Nucleotide excision repair:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:Function unknown:Signal transduction mechanisms:uvrC:met_pdase_I:asn_synth_AEB:rimI:spore_yabG:spore_yqfC:spore_yteA:Defense mechanisms:Amino acid biosynthesis:Energy Metabolism:Amino Acid Metabolism:Glycan Biosynthesis and Metabolism:Genetic Information Processing:Replication and Repair:Environmental Information Processing:Membrane Transport:Global:Metabolism:DNA metabolism:DNA replication, recombination, and repair:Protein synthesis:Ribosomal proteins: synthesis and modification:Protein fate:Protein modification and repair:Cellular processes:Sporulation and germination:Metabolism:Aspartate family:Information storage and processing:Cellular processes and signaling:Metabolism:Poorly characterized" 218 "Energy production and conversion:Phosphoglycerate dehydrogenase and related dehydrogenases:Predicted amidohydrolase:Methionine synthase II (cobalamin-independent):Signal transduction histidine kinase:Predicted dehydrogenases and related proteins:Putative intracellular protease/amidase:Membrane carboxypeptidase (penicillin-binding protein):Polyphosphate kinase:Amidases related to nicotinamidase:Metal-dependent amidase/aminoacylase/carboxypeptidase:Uncharacterized proteins, homologs of microcin C7 resistance protein MccF:3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases:Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain:Isocitrate lyase:Malate synthase:Uncharacterized conserved protein:Uncharacterized protein conserved in bacteria:Arabinose efflux permease:Putative NADH-flavin reductase:Predicted permeases:Uncharacterized conserved protein:Protein affecting phage T7 exclusion by the F plasmid:Uncharacterized conserved protein:Tryptophan 2,3-dioxygenase (vermilion):Kynureninase:Predicted membrane protein:Amino acid transport and metabolism:Carbohydrate transport and metabolism:Coenzyme transport and metabolism:Lipid transport and metabolism:Transcription:Cell wall/membrane/envelope biogenesis:Inorganic ion transport and metabolism:Oxidative phosphorylation:Glycine serine and threonine metabolism:Cysteine and methionine metabolism:Valine leucine and isoleucine degradation:Tryptophan metabolism:Peptidoglycan biosynthesis:Pyruvate metabolism:Glyoxylate and dicarboxylate metabolism:Methane metabolism:Nitrogen metabolism:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:Two-component system:RNA degradation:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:Function unknown:Signal transduction mechanisms:malate_syn_A:isocit_lyase:met_syn_B12ind:kynureninase:amidohydrolases:PBP_1a_fam:trp_2_3_diox:poly_P_kin:Defense mechanisms:Poorly characterized:Metabolism:Cellular processes and signaling:Information storage and processing:Biosynthesis and degradation of murein sacculus and peptidoglycan:Cell envelope:Aspartate family:Amino acid biosynthesis:Degradation of proteins, peptides, and glycopeptides:Protein fate:TCA cycle:Amino acids and amines:Energy metabolism:Phosphorus compounds:Central intermediary metabolism:Metabolism:Metabolism:Global:Signal Transduction:Environmental Information Processing:Folding Sorting and Degradation:Genetic Information Processing:Glycan Biosynthesis and Metabolism:Amino Acid Metabolism:Energy Metabolism:Carbohydrate Metabolism" 219 "Putative regulatory, ligand-binding protein related to C-terminal domains of K+ channels:Adenine/guanine phosphoribosyltransferases and related PRPP-binding proteins:Endonuclease IV:Phosphopantetheine adenylyltransferase:UDP-N-acetylmuramate-alanine ligase:Phosphatidylserine synthase:Phosphotransferase system, fructose-specific IIC component:Predicted metal-binding, possibly nucleic acid-binding protein:Predicted transcriptional regulator:Nucleotide transport and metabolism:Carbohydrate transport and metabolism:Coenzyme transport and metabolism:Lipid transport and metabolism:Transcription:Replication, recombination and repair:Cell wall/membrane/envelope biogenesis:Inorganic ion transport and metabolism:Glycine serine and threonine metabolism:D-Glutamine and D-glutamate metabolism:Peptidoglycan biosynthesis:Glycerophospholipid metabolism:Pantothenate and CoA biosynthesis:Metabolic pathways:Base excision repair:General function prediction only:cyt_tran_rel:pssA:nfo:murC:purR_Bsub:Metabolism:Lipid Metabolism:Amino Acid Metabolism:Metabolism of Other Amino Acids:Glycan Biosynthesis and Metabolism:Metabolism of Cofactors and Vitamins:Genetic Information Processing:Replication and Repair:Global:Metabolism:Fatty acid and phospholipid metabolism:Biosynthesis:Regulatory functions:DNA interactions:DNA metabolism:DNA replication, recombination, and repair:Cell envelope:Biosynthesis and degradation of murein sacculus and peptidoglycan:Information storage and processing:Cellular processes and signaling:Metabolism:Poorly characterized" 220 "2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway):Predicted transcriptional regulators:Glycine/D-amino acid oxidases (deaminating):1-deoxy-D-xylulose 5-phosphate reductoisomerase:Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases):Dihydroxyacetone kinase:Response regulator of the LytR/AlgR family:Uncharacterized protein conserved in bacteria:ABC-type maltose transport systems, permease component:Predicted Zn-dependent protease:Amino acid transport and metabolism:Carbohydrate transport and metabolism:Lipid transport and metabolism:Transcription:Posttranslational modification, protein turnover, chaperones:Glycerolipid metabolism:Methane metabolism:Terpenoid backbone biosynthesis:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:ABC transporters:Two-component system:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:Function unknown:Signal transduction mechanisms:Dxr:dhaK1:spore_yutH:Metabolism:Cellular processes and signaling:Information storage and processing:Other:Biosynthesis of cofactors, prosthetic groups, and carriers:Sporulation and germination:Cellular processes:Metabolism:Metabolism:Global:Signal Transduction:Membrane Transport:Environmental Information Processing:Metabolism of Terpenoids and Polyketides:Lipid Metabolism:Poorly characterized:Energy Metabolism" 221 "1-acyl-sn-glycerol-3-phosphate acyltransferase:Transcriptional regulator:Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily):Predicted xylanase/chitin deacetylase:Cell division protein FtsI/penicillin-binding protein 2:N-acetylglutamate synthase and related acetyltransferases:Subtilisin-like serine proteases:Uncharacterized conserved protein:Phosphotransferase system, HPr-related proteins:Sugar phosphate permease:Predicted secreted acid phosphatase:Amino acid transport and metabolism:Carbohydrate transport and metabolism:Lipid transport and metabolism:Transcription:Cell wall/membrane/envelope biogenesis:Posttranslational modification, protein turnover, chaperones:Glycerolipid metabolism:Glycerophospholipid metabolism:Metabolic pathways:General function prediction only:Function unknown:AGP_acyltrn:glpT:PTS_HPr_family:lipo_e_P4:Metabolism:Lipid Metabolism:Global:Metabolism:Fatty acid and phospholipid metabolism:Biosynthesis:Transport and binding proteins:Other:Biosynthesis of cofactors, prosthetic groups, and carriers:Pyridine nucleotides:Signal transduction:PTS:Information storage and processing:Cellular processes and signaling:Metabolism:Poorly characterized" 222 "Energy production and conversion:5'-3' exonuclease (including N-terminal domain of PolI):Nucleotide-binding protein implicated in inhibition of septum formation:Signal transduction histidine kinase:Adenine-specific DNA methylase:Predicted nucleoside-diphosphate sugar epimerase:Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog):Transcriptional regulator:Uncharacterized protein conserved in bacteria:Na+/H+ antiporter:Transcriptional regulators:DNA repair proteins:Membrane protein involved in the export of O-antigen and teichoic acid:Predicted hydrolase (metallo-beta-lactamase superfamily):Predicted membrane protein:Predicted O-methyltransferase:Signal transduction histidine kinase:Predicted membrane protein:Cell cycle control, cell division, chromosome partitioning:Translation, ribosomal structure and biogenesis:Transcription:Replication, recombination and repair:Two-component system:General function prediction only:Function unknown:Signal transduction mechanisms:maf:TIGR00282:radc:yfcH:spore_yabP:spore_yabQ:Hypothetical proteins:Sporulation and germination:Cell division:Cellular processes:DNA replication, recombination, and repair:DNA metabolism:Poorly characterized:Signal Transduction:Metabolism:Cellular processes and signaling:Environmental Information Processing:Information storage and processing:Enzymes of unknown specificity:Unknown function:Conserved" 223 "Acetyltransferases:Transcriptional regulator:Membrane carboxypeptidase (penicillin-binding protein):Cell division protein FtsI/penicillin-binding protein 2:Alanine racemase:Predicted UDP-glucose 6-dehydrogenase:Predicted glycosyltransferases:Hemolysins and related proteins containing CBS domains:DNA repair photolyase:FOG: GAF domain:Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein):Signal transduction histidine kinase:Phage terminase-like protein, large subunit:Transcription:Replication, recombination and repair:Cell wall/membrane/envelope biogenesis:Pentose and glucuronate interconversions:Ascorbate and aldarate metabolism:Tyrosine metabolism:Benzoate degradation:D-Alanine metabolism:Starch and sucrose metabolism:Amino sugar and nucleotide sugar metabolism:Naphthalene degradation:Aminobenzoate degradation:Ethylbenzene degradation:Limonene and pinene degradation:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:General function prediction only:Signal transduction mechanisms:alr:GPR:PBP_1a_fam:spore_ger_x_C:NDP-sugDHase:photo_TT_lyase:LTA_DltD:Cellular processes and signaling:Information storage and processing:Biosynthesis and degradation of murein sacculus and peptidoglycan:Cell envelope:Sporulation and germination:Cellular processes:Metabolism:Metabolism:Global:Xenobiotics Biodegradation and Metabolism:Metabolism of Terpenoids and Polyketides:Metabolism of Other Amino Acids:Amino Acid Metabolism:Poorly characterized:Carbohydrate Metabolism" 224 "Transaldolase:Membrane protease subunits, stomatin/prohibitin homologs:Lactoylglutathione lyase and related lyases:Methylated DNA-protein cysteine methyltransferase:ADP-ribose pyrophosphatase:Transcriptional regulator:Fructose-1,6-bisphosphatase/sedoheptulose 1,7-bisphosphatase and related proteins:Phosphatidylserine/phosphatidylglycerophosphate/cardiolipin synthases and related enzymes:Membrane protein implicated in regulation of membrane protease activity:Adenosine deaminase:Uncharacterized conserved protein:Amino acid transport and metabolism:Nucleotide transport and metabolism:Carbohydrate transport and metabolism:Lipid transport and metabolism:Transcription:Replication, recombination and repair:Posttranslational modification, protein turnover, chaperones:Glycolysis / Gluconeogenesis:Pentose phosphate pathway:Fructose and mannose metabolism:Glycerophospholipid metabolism:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:Function unknown:glpX:ogt:fsa_talC_mipB:LPXTG_anchor:Intracellular trafficking, secretion, and vesicular transport:Cellular processes and signaling:Carbohydrate Metabolism:Lipid Metabolism:Global:Metabolism:Energy metabolism:Pentose phosphate pathway:DNA metabolism:DNA replication, recombination, and repair:Cell envelope:Other:Information storage and processing:Metabolism:Metabolism:Poorly characterized" 225 "Mg-dependent DNase:Glycosidases:Uncharacterized conserved protein:Predicted transcriptional regulators:Exonuclease III:Predicted HD superfamily hydrolase:Uncharacterized conserved protein:S-adenosylmethionine decarboxylase:Uncharacterized protein conserved in bacteria:Beta-lactamase class C and other penicillin binding proteins:AraC-type DNA-binding domain-containing proteins:Predicted membrane protein:Uncharacterized protein conserved in bacteria:Amino acid transport and metabolism:Carbohydrate transport and metabolism:Transcription:Replication, recombination and repair:Galactose metabolism:Cysteine and methionine metabolism:Arginine and proline metabolism:Starch and sucrose metabolism:Metabolic pathways:Base excision repair:General function prediction only:Function unknown:TIGR00010:exoDNase_III:SAM_DCase_Bsu:Defense mechanisms:Cellular processes and signaling:Carbohydrate Metabolism:Amino Acid Metabolism:Genetic Information Processing:Replication and Repair:Global:Metabolism:Central intermediary metabolism:Polyamine biosynthesis:DNA metabolism:DNA replication, recombination, and repair:Unknown function:Enzymes of unknown specificity:Information storage and processing:Metabolism:Metabolism:Poorly characterized" 226 "Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases:Predicted hydrolase of the metallo-beta-lactamase superfamily:Uncharacterized protein conserved in bacteria:Uncharacterized protein conserved in bacteria:Preprotein translocase subunit YajC:DNA-directed RNA polymerase, delta subunit:Uncharacterized conserved protein:Uncharacterized protein conserved in bacteria:Negative regulator of septation ring formation:Uncharacterized protein conserved in bacteria:Gas vesicle protein:Cell cycle control, cell division, chromosome partitioning:Nucleotide transport and metabolism:Carbohydrate transport and metabolism:Transcription:Purine metabolism:Pyrimidine metabolism:Metabolic pathways:RNA degradation:RNA polymerase:Protein export:Bacterial secretion system:General function prediction only:Function unknown:MG423:yajC:DegV:thiopep_precurs:Intracellular trafficking, secretion, and vesicular transport:Cellular processes and signaling:Metabolism:Poorly characterized:Protein and peptide secretion and trafficking:Protein fate:Metabolism:Global:Metabolism:Membrane Transport:Environmental Information Processing:Folding Sorting and Degradation:Transcription:Genetic Information Processing:Cellular processes:Nucleotide Metabolism:Toxin production and resistance:Hypothetical proteins:Conserved:Unknown function:General:Information storage and processing" 227 "Energy production and conversion:Lipoate-protein ligase A:Nucleoside diphosphate kinase:Carbonic anhydrase:Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily):Bacterial nucleoid DNA-binding protein:Predicted RNA binding protein (contains ribosomal protein S1 domain):Inorganic pyrophosphatase/exopolyphosphatase:Predicted redox protein, regulator of disulfide bond formation:Predicted hydrolases of HD superfamily:Di- and tripeptidases:Uncharacterized conserved protein:Uncharacterized conserved protein:Amino acid transport and metabolism:Nucleotide transport and metabolism:Coenzyme transport and metabolism:Translation, ribosomal structure and biogenesis:Replication, recombination and repair:Posttranslational modification, protein turnover, chaperones:Inorganic ion transport and metabolism:Oxidative phosphorylation:Purine metabolism:Pyrimidine metabolism:Arginine and proline metabolism:Histidine metabolism:beta-Alanine metabolism:Glutathione metabolism:Lipoic acid metabolism:Nitrogen metabolism:Metabolic pathways:Biosynthesis of secondary metabolites:Two-component system:General function prediction only:Function unknown:lipoyltrans:aa-his-dipept:Environmental Information Processing:Metabolism of Cofactors and Vitamins:Metabolism:Metabolism of Other Amino Acids:Amino Acid Metabolism:Nucleotide Metabolism:Cellular processes and signaling:Energy Metabolism:Metabolism:Poorly characterized:Information storage and processing:Protein modification and repair:Protein fate:Metabolism:Global:Signal Transduction" 228 "Energy production and conversion:Superfamily II DNA helicase:Predicted oxidoreductases (related to aryl-alcohol dehydrogenases):Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain:Uncharacterized conserved protein:Uncharacterized protein conserved in bacteria:Uncharacterized conserved protein:Cyclopropane fatty acid synthase and related methyltransferases:Arabinose efflux permease:Predicted membrane protein:Protein required for the initiation of cell division:Cell cycle control, cell division, chromosome partitioning:Carbohydrate transport and metabolism:Transcription:Replication, recombination and repair:Cell wall/membrane/envelope biogenesis:Ascorbate and aldarate metabolism:Metabolic pathways:Biosynthesis of secondary metabolites:RNA degradation:Function unknown:Signal transduction mechanisms:recQ_fam:ftsL_broad:exospor_lead:Metabolism:Carbohydrate Metabolism:Genetic Information Processing:Folding Sorting and Degradation:Global:Metabolism:DNA metabolism:DNA replication, recombination, and repair:Cellular processes:Cell division:Sporulation and germination:Information storage and processing:Cellular processes and signaling:Metabolism:Poorly characterized" 229 "Energy production and conversion:FAD/FMN-containing dehydrogenases:Biotin carboxylase:NADH:ubiquinone oxidoreductase 49 kD subunit 7:Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain:Glutamate racemase:NADH:ubiquinone oxidoreductase subunit 1 (chain H):NADH:ubiquinone oxidoreductase subunit 4 (chain M):ABC-type antimicrobial peptide transport system, ATPase component:3-hydroxyacyl-CoA dehydrogenase:Acyl-CoA dehydrogenases:Allophanate hydrolase subunit 2:2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase:ABC-type phosphate/phosphonate transport system, permease component:Predicted membrane protein:Ornithine/acetylornithine aminotransferase:Amino acid transport and metabolism:Coenzyme transport and metabolism:Lipid transport and metabolism:Transcription:Cell wall/membrane/envelope biogenesis:Inorganic ion transport and metabolism:Oxidative phosphorylation:Geraniol degradation:Arginine and proline metabolism:Benzoate degradation:D-Glutamine and D-glutamate metabolism:Naphthalene degradation:Butanoate metabolism:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:ABC transporters:Function unknown:Signal transduction mechanisms:glut_race:urea_amlyse_rel:PhnE:bact_FAD_ox:NDH_I_M:spore_ger_x_C:Defense mechanisms:Cellular processes:Anions:Transport and binding proteins:Electron transport:Energy metabolism:Metabolism:Global:Metabolism:Membrane Transport:Environmental Information Processing:Xenobiotics Biodegradation and Metabolism:Metabolism of Terpenoids and Polyketides:Metabolism of Other Amino Acids:Amino Acid Metabolism:Energy Metabolism:Sporulation and germination:Carbohydrate Metabolism:Unknown function:General:Cell envelope:Biosynthesis and degradation of murein sacculus and peptidoglycan:Information storage and processing:Cellular processes and signaling:Metabolism:Poorly characterized" 230 "Acetyltransferase (isoleucine patch superfamily):Thymidylate kinase:UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N-acetylglucosamine-1-phosphate transferase:Predicted phosphatases:Signal transduction histidine kinase:Permeases of the drug/metabolite transporter (DMT) superfamily:Uncharacterized membrane protein, putative virulence factor:Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain:Uncharacterized low-complexity proteins:Transcriptional regulators:Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain:Sugar phosphate permease:Predicted membrane protein:Signal transduction histidine kinase:L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily:Amino acid transport and metabolism:Nucleotide transport and metabolism:Carbohydrate transport and metabolism:Transcription:Cell wall/membrane/envelope biogenesis:Oxidative phosphorylation:Pyrimidine metabolism:Tyrosine metabolism:Benzoate degradation:Peptidoglycan biosynthesis:Naphthalene degradation:Aminobenzoate degradation:Ethylbenzene degradation:Limonene and pinene degradation:Metabolic pathways:Microbial metabolism in diverse environments:General function prediction only:Function unknown:Signal transduction mechanisms:DTMP_kinase:mraY:efflux_Bcr_CflA:HAD-SF-IA-v3:Cellular processes and signaling:Information storage and processing:Biosynthesis and degradation of murein sacculus and peptidoglycan:Cell envelope:Enzymes of unknown specificity:Unknown function:Nucleotide and nucleoside interconversions:Purines, pyrimidines, nucleosides, and nucleotides:Metabolism:Metabolism:Global:Xenobiotics Biodegradation and Metabolism:Metabolism of Terpenoids and Polyketides:Glycan Biosynthesis and Metabolism:Amino Acid Metabolism:Nucleotide Metabolism:Poorly characterized:Energy Metabolism:Metabolism" 231 "Energy production and conversion:Predicted GTPase, probable translation factor:Transcription antiterminator:Cytidylate kinase:Membrane GTPase LepA:Adenine/guanine phosphoribosyltransferases and related PRPP-binding proteins:Superfamily II DNA and RNA helicases:Preprotein translocase subunit SecE:Enzyme involved in the deoxyxylulose pathway of isoprenoid biosynthesis:Polyribonucleotide nucleotidyltransferase (polynucleotide phosphorylase):NADH dehydrogenase, FAD-containing subunit:Fructose-1,6-bisphosphatase/sedoheptulose 1,7-bisphosphatase and related proteins:Nucleotide transport and metabolism:Carbohydrate transport and metabolism:Lipid transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:Replication, recombination and repair:Cell wall/membrane/envelope biogenesis:Glycolysis / Gluconeogenesis:Pentose phosphate pathway:Fructose and mannose metabolism:Oxidative phosphorylation:Purine metabolism:Pyrimidine metabolism:Terpenoid backbone biosynthesis:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:RNA degradation:Protein export:Bacterial secretion system:cmk:TIGR00092:small_GTP:glpX:ispG_gcpE:nusG:secE_bact:apt:polynuc_phos:Intracellular trafficking, secretion, and vesicular transport:Unknown function:Carbohydrate Metabolism:Energy Metabolism:Nucleotide Metabolism:Metabolism of Terpenoids and Polyketides:Genetic Information Processing:Folding Sorting and Degradation:Environmental Information Processing:Membrane Transport:Global:Metabolism:Energy metabolism:Pentose phosphate pathway:Purines, pyrimidines, nucleosides, and nucleotides:Nucleotide and nucleoside interconversions:Salvage of nucleosides and nucleotides:Transcription:Degradation of RNA:Transcription factors:Protein fate:Protein and peptide secretion and trafficking:Metabolism:General:Biosynthesis of cofactors, prosthetic groups, and carriers:Other:Information storage and processing:Cellular processes and signaling:Metabolism" 232 "Energy production and conversion:Citrate synthase:Non-ribosomal peptide synthetase modules and related proteins:Peroxiredoxin:Posttranslational modification, protein turnover, chaperones:Citrate cycle (TCA cycle):Glyoxylate and dicarboxylate metabolism:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:Secondary metabolites biosynthesis, transport and catabolism:NRPS-para261:phgtail_TP901_1:TQXA_dom:Cellular processes and signaling:Metabolism:Prophage functions:Mobile and extrachromosomal element functions:Metabolism:Metabolism:Global:Carbohydrate Metabolism" 233 "Energy production and conversion:Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase:Glutathione peroxidase:Fructose-2,6-bisphosphatase:Thioredoxin reductase:Thiol-disulfide isomerase and thioredoxins:NAD-dependent aldehyde dehydrogenases:Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases):Uncharacterized membrane protein:Predicted transcriptional regulators:Ketopantoate reductase:Mn2+ and Fe2+ transporters of the NRAMP family:Arylamine N-acetyltransferase:Di- and tripeptidases:Uncharacterized enzyme involved in biosynthesis of extracellular polysaccharides:DNA alkylation repair enzyme:Predicted esterase of the alpha-beta hydrolase superfamily:Amino acid transport and metabolism:Carbohydrate transport and metabolism:Coenzyme transport and metabolism:Lipid transport and metabolism:Transcription:Replication, recombination and repair:Posttranslational modification, protein turnover, chaperones:Inorganic ion transport and metabolism:Glycolysis / Gluconeogenesis:Pyrimidine metabolism:Lysine degradation:Arginine and proline metabolism:Phenylalanine metabolism:D-Arginine and D-ornithine metabolism:D-Alanine metabolism:Glutathione metabolism:Arachidonic acid metabolism:Methane metabolism:Pantothenate and CoA biosynthesis:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:Function unknown:apbA_panE:D_amino_aminoT:nramp:TRX_reduct:peptidase-T:spo_II_M:Cellular processes and signaling:Information storage and processing:Pantothenate and coenzyme A:Biosynthesis of cofactors, prosthetic groups, and carriers:Sporulation and germination:Cellular processes:Cations and iron carrying compounds:Transport and binding proteins:Degradation of proteins, peptides, and glycopeptides:Protein fate:Electron transport:Amino acids and amines:Energy metabolism:Metabolism:Metabolism:Global:Metabolism of Cofactors and Vitamins:Metabolism of Other Amino Acids:Amino Acid Metabolism:Nucleotide Metabolism:Lipid Metabolism:Energy Metabolism:Poorly characterized:Carbohydrate Metabolism:Metabolism" 234 "Energy production and conversion:Malic enzyme:Pyrroline-5-carboxylate reductase:Adenine/guanine phosphoribosyltransferases and related PRPP-binding proteins:Alanine dehydrogenase:Aspartate ammonia-lyase:Uncharacterized ABC-type transport system, permease component:Fructose-1-phosphate kinase and related fructose-6-phosphate kinase (PfkB):Transcriptional regulators of sugar metabolism:Phosphotransferase system cellobiose-specific component IIA:Uncharacterized ABC-type transport system, periplasmic component/surface lipoprotein:Phosphoenolpyruvate carboxykinase (ATP):Nucleoside permease:Transcriptional regulators:Xanthine/uracil permeases:Permeases:Na+/citrate symporter:Uncharacterized protein conserved in bacteria:ABC-type uncharacterized transport systems, ATPase components:Amino acid transport and metabolism:Nucleotide transport and metabolism:Carbohydrate transport and metabolism:Transcription:Glycolysis / Gluconeogenesis:Citrate cycle (TCA cycle):Fructose and mannose metabolism:Purine metabolism:Alanine aspartate and glutamate metabolism:Arginine and proline metabolism:Taurine and hypotaurine metabolism:Pyruvate metabolism:Nitrogen metabolism:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:Two-component system:Phosphotransferase system (PTS):General function prediction only:Function unknown:proC:pckA:alaDH:ncs2:aspA:XPRTase:1-PFK:Metabolism:Carbohydrate Metabolism:Energy Metabolism:Nucleotide Metabolism:Amino Acid Metabolism:Metabolism of Other Amino Acids:Environmental Information Processing:Membrane Transport:Signal Transduction:Global:Metabolism:Energy metabolism:Amino acids and amines:Glycolysis/gluconeogenesis:Purines, pyrimidines, nucleosides, and nucleotides:Salvage of nucleosides and nucleotides:Transport and binding proteins:Nucleosides, purines and pyrimidines:Amino acid biosynthesis:Glutamate family:Information storage and processing:Metabolism:Poorly characterized" 235 "Energy production and conversion:Fe-S oxidoreductase:Predicted S-adenosylmethionine-dependent methyltransferase involved in cell envelope biogenesis:Topoisomerase IA:Predicted permease:Predicted integral membrane protein:Uncharacterized conserved protein containing a ferredoxin-like domain:Uncharacterized conserved protein:Uncharacterized conserved protein:Uncharacterized conserved protein:Uncharacterized conserved protein:Acetyltransferases, including N-acetylases of ribosomal proteins:Zn-dependent proteases:Uncharacterized protein with SCP/PR1 domains:Predicted membrane protein:Translation, ribosomal structure and biogenesis:Replication, recombination and repair:Cell wall/membrane/envelope biogenesis:General function prediction only:Function unknown:TIGR00006:TIGR00273:TIGR00726:topB:spore_ytvI:Cellular processes:DNA replication, recombination, and repair:DNA metabolism:Electron transport:Energy metabolism:General:Metabolism:Poorly characterized:Information storage and processing:Biosynthesis and degradation of murein sacculus and peptidoglycan:Cell envelope:Cellular processes and signaling:Unknown function:Sporulation and germination" 236 "Tyrosyl-tRNA synthetase:Prolyl-tRNA synthetase:ATPase components of ABC transporters with duplicated ATPase domains:SAM-dependent methyltransferases:CTP synthase (UTP-ammonia lyase):Superfamily II DNA and RNA helicases:Arylsulfatase regulator (Fe-S oxidoreductase):Uncharacterized homolog of plant Iojap protein:Na+/H+ antiporter NhaD and related arsenite permeases:NAD(FAD)-utilizing enzyme possibly involved in translation:Predicted membrane protein:Cystathionine beta-lyase family protein involved in aluminum resistance:Nucleotide transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:Replication, recombination and repair:Inorganic ion transport and metabolism:Pyrimidine metabolism:Histidine metabolism:Tyrosine metabolism:Selenocompound metabolism:Polycyclic aromatic hydrocarbon degradation:Aminoacyl-tRNA biosynthesis:Metabolic pathways:Microbial metabolism in diverse environments:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:Function unknown:iojap_ybeB:gid_trmFO:tyrS:PyrG:proS_fam_II:Metabolism:Information storage and processing:General:Unknown function:tRNA and rRNA base modification:tRNA aminoacylation:Protein synthesis:Pyrimidine ribonucleotide biosynthesis:Purines, pyrimidines, nucleosides, and nucleotides:Metabolism:Metabolism:Global:Translation:Genetic Information Processing:Xenobiotics Biodegradation and Metabolism:Metabolism of Other Amino Acids:Amino Acid Metabolism:Poorly characterized:Nucleotide Metabolism" 237 "Cysteine synthase:1,4-alpha-glucan branching enzyme:Glycogen synthase:Molybdopterin biosynthesis enzyme:Molybdopterin converting factor, large subunit:ADP-glucose pyrophosphorylase:Uracil DNA glycosylase:ABC-type multidrug transport system, ATPase component:ABC-type transport system involved in multi-copper enzyme maturation, permease component:Transcriptional regulators:Molybdopterin-guanine dinucleotide biosynthesis protein:Site-specific recombinases, DNA invertase Pin homologs:Nitrate/nitrite transporter:Molybdenum cofactor biosynthesis enzyme:Predicted aminoglycoside phosphotransferase:Uncharacterized protein conserved in bacteria:Signal transduction histidine kinase regulating citrate/malate metabolism:Predicted acetyltransferase:Response regulator of citrate/malate metabolism:Amino acid transport and metabolism:Carbohydrate transport and metabolism:Coenzyme transport and metabolism:Transcription:Replication, recombination and repair:Inorganic ion transport and metabolism:Cysteine and methionine metabolism:Selenocompound metabolism:Starch and sucrose metabolism:Amino sugar and nucleotide sugar metabolism:Sulfur metabolism:Metabolic pathways:Microbial metabolism in diverse environments:ABC transporters:Two-component system:Base excision repair:Sulfur relay system:General function prediction only:Function unknown:Signal transduction mechanisms:mobB:molyb_syn:ung:cysKM:branching_enzym:glgC:glgA:moaA:Defense mechanisms:Biosynthesis of cofactors, prosthetic groups, and carriers:Serine family:Amino acid biosynthesis:DNA replication, recombination, and repair:DNA metabolism:Biosynthesis and degradation of polysaccharides:Energy metabolism:Metabolism:Metabolism:Global:Signal Transduction:Membrane Transport:Environmental Information Processing:Replication and Repair:Folding Sorting and Degradation:Genetic Information Processing:Metabolism of Other Amino Acids:Amino Acid Metabolism:Energy Metabolism:Poorly characterized:Carbohydrate Metabolism:Metabolism:Cellular processes and signaling:Information storage and processing:Molybdopterin" 238 "Acetyltransferase (isoleucine patch superfamily):Single-stranded DNA-binding protein:Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain:Transcription elongation factor:Putative transcription activator:Predicted acetyltransferases and hydrolases with the alpha/beta hydrolase fold:Amidases related to nicotinamidase:Acetyltransferases, including N-acetylases of ribosomal proteins:Beta-lactamase class C and other penicillin binding proteins:Inosine-uridine nucleoside N-ribohydrolase:Uncharacterized protein conserved in bacteria:Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain:Nucleotide transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:Replication, recombination and repair:Purine metabolism:Thiamine metabolism:Nicotinate and nicotinamide metabolism:Biosynthesis of siderophore group nonribosomal peptides:Metabolic pathways:Biosynthesis of secondary metabolites:Two-component system:Flagellar assembly:DNA replication:Mismatch repair:Homologous recombination:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:Function unknown:Signal transduction mechanisms:sensory_box:ssb:greA:B_an_ocin:Defense mechanisms:Metabolism:Nucleotide Metabolism:Metabolism of Cofactors and Vitamins:Metabolism of Terpenoids and Polyketides:Genetic Information Processing:Replication and Repair:Environmental Information Processing:Signal Transduction:Cellular Processes:Cell Motility:Global:Metabolism:Regulatory functions:Small molecule interactions:DNA metabolism:DNA replication, recombination, and repair:Transcription:Transcription factors:Cellular processes:Toxin production and resistance:Information storage and processing:Cellular processes and signaling:Metabolism:Poorly characterized" 239 "Glycosyltransferases involved in cell wall biogenesis:Catalase:Amidases related to nicotinamidase:Phosphotransferase system cellobiose-specific component IIA:Uncharacterized phage-encoded protein:Carbohydrate transport and metabolism:Cell wall/membrane/envelope biogenesis:Inorganic ion transport and metabolism:Tryptophan metabolism:Methane metabolism:Metabolic pathways:Microbial metabolism in diverse environments:Phosphotransferase system (PTS):Secondary metabolites biosynthesis, transport and catabolism:Function unknown:phage_pRha:Prophage functions:Energy Metabolism:Amino Acid Metabolism:Environmental Information Processing:Membrane Transport:Global:Metabolism:Mobile and extrachromosomal element functions:Metabolism:Cellular processes and signaling:Metabolism:Poorly characterized" 240 "Chorismate synthase:Cysteinyl-tRNA synthetase:N-formylmethionyl-tRNA deformylase:Glycosyltransferase:NAD/FAD-utilizing enzyme apparently involved in cell division:Phosphopantothenoylcysteine synthetase/decarboxylase:Serine/threonine protein kinase:rRNA methylases:tRNA nucleotidyltransferase/poly(A) polymerase:Serine/threonine protein phosphatase:Serine acetyltransferase:Panthothenate kinase:dTDP-D-glucose 4,6-dehydratase:dTDP-4-dehydrorhamnose reductase:Transcription-repair coupling factor (superfamily II helicase):Primosomal protein N' (replication factor Y) - superfamily II helicase:RecG-like helicase:Disulfide bond chaperones of the HSP33 family:Putative transcriptional regulator, homolog of Bvg accessory factor:Exonuclease VII, large subunit:Exonuclease VII small subunit:Methylglyoxal synthase:dTDP-4-dehydrorhamnose 3,5-epimerase and related enzymes:Uncharacterized protein conserved in bacteria:Uncharacterized proteins, LmbE homologs:Cell cycle control, cell division, chromosome partitioning:Amino acid transport and metabolism:Carbohydrate transport and metabolism:Coenzyme transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:Replication, recombination and repair:Cell wall/membrane/envelope biogenesis:Posttranslational modification, protein turnover, chaperones:Pyrimidine metabolism:Cysteine and methionine metabolism:Phenylalanine tyrosine and tryptophan biosynthesis:Streptomycin biosynthesis:Polyketide sugar unit biosynthesis:Pyruvate metabolism:Pantothenate and CoA biosynthesis:Sulfur metabolism:Aminoacyl-tRNA biosynthesis:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:Nucleotide excision repair:Mismatch repair:Homologous recombination:General function prediction only:Function unknown:Signal transduction mechanisms:aroC:pept_deformyl:gidA:MGSA:rRNA_methyl_3:xseA:cysS:coaBC_dfp:mfd:priA:recG:baf:cysE:dTDP_gluc_dehyt:rmlD:rmlC:xseB:thiol_BshA:thiol_BshB1:Replication and Repair:Translation:Genetic Information Processing:Biosynthesis of Other Secondary Metabolites:Metabolism of Terpenoids and Polyketides:Metabolism of Cofactors and Vitamins:Amino Acid Metabolism:Nucleotide Metabolism:Energy Metabolism:Carbohydrate Metabolism:Energy metabolism:Other:DNA metabolism:Degradation of DNA:DNA replication, recombination, and repair:Protein synthesis:tRNA aminoacylation:tRNA and rRNA base modification:Protein fate:Protein modification and repair:Amino acid biosynthesis:Aromatic amino acid family:Serine family:Biosynthesis of cofactors, prosthetic groups, and carriers:Pantothenate and coenzyme A:Glutathione and analogs:Cell envelope:Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides:Information storage and processing:Cellular processes and signaling:Metabolism:Poorly characterized:Metabolism:Metabolism:Global" 241 "Permeases of the drug/metabolite transporter (DMT) superfamily:Transcription elongation factor:Predicted hydrolase (HAD superfamily):ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component:Uncharacterized protein conserved in bacteria:Predicted transcriptional regulators:DnaK suppressor protein:Uncharacterized protein conserved in bacteria:Molybdopterin converting factor, small subunit:Putative stress-responsive transcriptional regulator:Arylamine N-acetyltransferase:Na+/melibiose symporter and related transporters:Uncharacterized conserved protein:Mn-containing catalase:UV damage repair endonuclease:Uncharacterized protein conserved in bacteria:Amino acid transport and metabolism:Carbohydrate transport and metabolism:Coenzyme transport and metabolism:Transcription:Replication, recombination and repair:Inorganic ion transport and metabolism:ABC transporters:Sulfur relay system:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:Function unknown:Signal transduction mechanisms:uvde:greA:HAD-SF-IA-v1:moaD:spore_gerQ:spore_yteA:exospor_lead:Poorly characterized:Metabolism:Cellular processes and signaling:Information storage and processing:Molybdopterin:Biosynthesis of cofactors, prosthetic groups, and carriers:Enzymes of unknown specificity:Unknown function:Sporulation and germination:Cellular processes:Transcription factors:Transcription:DNA replication, recombination, and repair:DNA metabolism:Genetic Information Processing:Membrane Transport:Environmental Information Processing:Folding Sorting and Degradation" 242 "3-methyladenine DNA glycosylase/8-oxoguanine DNA glycosylase:Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain:Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain:Septum formation inhibitor:Actin-like ATPase involved in cell morphogenesis:Predicted GTPases:Protein involved in ribonucleotide reduction:Cell shape-determining protein:DNA repair proteins:Nitrate/nitrite transporter:SAM-dependent methyltransferases related to tRNA (uracil-5-)-methyltransferase:Sortase (surface protein transpeptidase):Cell cycle control, cell division, chromosome partitioning:Nucleotide transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:Replication, recombination and repair:Cell wall/membrane/envelope biogenesis:Posttranslational modification, protein turnover, chaperones:Inorganic ion transport and metabolism:Histidine metabolism:Tyrosine metabolism:Selenocompound metabolism:Polycyclic aromatic hydrocarbon degradation:Microbial metabolism in diverse environments:Base excision repair:General function prediction only:Signal transduction mechanisms:TIGR00157:mreC:nrdI:rumA:radc:mreB:sortase_fam:minC:Cellular processes and signaling:Metabolism:Poorly characterized:Translation factors:tRNA and rRNA base modification:Protein synthesis:DNA replication, recombination, and repair:DNA metabolism:2'-Deoxyribonucleotide metabolism:Purines, pyrimidines, nucleosides, and nucleotides:Metabolism:Metabolism:Global:Replication and Repair:Genetic Information Processing:Xenobiotics Biodegradation and Metabolism:Metabolism of Other Amino Acids:Protein fate:Amino Acid Metabolism:Protein and peptide secretion and trafficking:Cellular processes:Cell division:Cell envelope:Biosynthesis and degradation of murein sacculus and peptidoglycan:Information storage and processing" 243 "Peptidyl-tRNA hydrolase:Kef-type K+ transport systems, membrane components:Na+-driven multidrug efflux pump:Superfamily II DNA/RNA helicases, SNF2 family:2-methylthioadenine synthetase:Coproporphyrinogen III oxidase and related Fe-S oxidoreductases:Predicted dehydrogenases and related proteins:N6-adenine-specific methylase:Bacterial cell division membrane protein:Peroxiredoxin:Transcriptional regulator:Putative NADH-flavin reductase:Homogentisate 1,2-dioxygenase:ABC-type uncharacterized transport system, permease component:Response regulator of citrate/malate metabolism:ABC-type uncharacterized transport system, ATPase component:Integral membrane protein (PIN domain superfamily):Cell cycle control, cell division, chromosome partitioning:Coenzyme transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:Replication, recombination and repair:Posttranslational modification, protein turnover, chaperones:Inorganic ion transport and metabolism:Tyrosine metabolism:Styrene degradation:Porphyrin and chlorophyll metabolism:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:Two-component system:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:Signal transduction mechanisms:TIGR00089:TIGR00095:pth:hemN_rel:matE:Defense mechanisms:Metabolism:Amino Acid Metabolism:Metabolism of Cofactors and Vitamins:Xenobiotics Biodegradation and Metabolism:Environmental Information Processing:Signal Transduction:Global:Metabolism:Protein synthesis:Other:tRNA and rRNA base modification:Transport and binding proteins:Other:Biosynthesis of cofactors, prosthetic groups, and carriers:Heme, porphyrin, and cobalamin:Information storage and processing:Cellular processes and signaling:Metabolism:Poorly characterized" 244 "Ketol-acid reductoisomerase:3-isopropylmalate dehydratase small subunit:Lactoylglutathione lyase and related lyases:Predicted permeases:Glutamate racemase:D-alanine-D-alanine ligase and related ATP-grasp enzymes:Predicted acyltransferases:Glycerate kinase:2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase:Predicted flavin-nucleotide-binding protein structurally related to pyridoxine 5'-phosphate oxidase:Lyzozyme M1 (1,4-beta-N-acetylmuramidase):Amino acid transport and metabolism:Carbohydrate transport and metabolism:Coenzyme transport and metabolism:Lipid transport and metabolism:Cell wall/membrane/envelope biogenesis:Glycine serine and threonine metabolism:Valine leucine and isoleucine biosynthesis:D-Glutamine and D-glutamate metabolism:D-Alanine metabolism:Peptidoglycan biosynthesis:Glycerolipid metabolism:Glyoxylate and dicarboxylate metabolism:C5-Branched dibasic acid metabolism:Methane metabolism:Pantothenate and CoA biosynthesis:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:General function prediction only:TIGR00045:glut_race:leuD:ilvC:D_ala_D_alaTIGR:PPOX_FMN_DR2398:Metabolism:Poorly characterized:Biosynthesis and degradation of murein sacculus and peptidoglycan:Cell envelope:Pyruvate family:Amino acid biosynthesis:Other:Energy metabolism:Metabolism:Metabolism:Global:Metabolism of Cofactors and Vitamins:Glycan Biosynthesis and Metabolism:Metabolism of Other Amino Acids:Amino Acid Metabolism:Lipid Metabolism:Energy Metabolism:Cellular processes and signaling:Carbohydrate Metabolism" 245 "Energy production and conversion:Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain:Uncharacterized membrane-associated protein:ABC-type Fe3+-hydroxamate transport system, periplasmic component:Predicted permeases:ABC-type antimicrobial peptide transport system, ATPase component:16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases:Inactive homolog of metal-dependent proteases, putative molecular chaperone:Transcriptional regulator:Predicted transcriptional regulators:Transposase and inactivated derivatives:Uncharacterized iron-regulated membrane protein:Predicted lipoprotein involved in nitrous oxide reduction:Translation, ribosomal structure and biogenesis:Transcription:Replication, recombination and repair:Posttranslational modification, protein turnover, chaperones:Inorganic ion transport and metabolism:Sulfur metabolism:Metabolic pathways:Microbial metabolism in diverse environments:ABC transporters:General function prediction only:Function unknown:TIGR00093:2A0309:hlyII:spore_BofA:bact_YeaZ:Defense mechanisms:Toxin production and resistance:Cellular processes:Amino acids, peptides and amines:Transport and binding proteins:tRNA and rRNA base modification:Protein synthesis:Metabolism:Metabolism:Global:Membrane Transport:Environmental Information Processing:Poorly characterized:Energy Metabolism:Metabolism:Cellular processes and signaling:Information storage and processing:Sporulation and germination" 246 "Kef-type K+ transport systems, membrane components:Putative regulatory, ligand-binding protein related to C-terminal domains of K+ channels:Uncharacterized membrane-associated protein:Shikimate kinase:Uncharacterized membrane protein:Transcriptional regulators:Acetyltransferases, including N-acetylases of ribosomal proteins:Transcriptional regulators:Transcriptional regulators:Predicted transcriptional regulator:Uncharacterized protein conserved in bacteria:Amino acid transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:Inorganic ion transport and metabolism:Arginine and proline metabolism:Phenylalanine tyrosine and tryptophan biosynthesis:Metabolic pathways:Biosynthesis of secondary metabolites:Function unknown:Amino Acid Metabolism:Metabolism:Poorly characterized:Metabolism:Information storage and processing:Metabolism:Global" 247 "Energy production and conversion:Fe-S oxidoreductase:Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain:Protoheme ferro-lyase (ferrochelatase):FAD/FMN-containing dehydrogenases:Fe2+/Zn2+ uptake regulation proteins:Catalase:Parvulin-like peptidyl-prolyl isomerase:DNA-binding ferritin-like protein (oxidative damage protectant):Acyl carrier protein phosphodiesterase:Putative effector of murein hydrolase:Putative effector of murein hydrolase LrgA:Arsenate reductase and related proteins, glutaredoxin family:Small primase-like proteins (Toprim domain):Predicted transcriptional regulators:Pirin-related protein:Transcriptional regulators:Predicted transcriptional regulator:Uncharacterized protein conserved in bacteria:Arabinose efflux permease:Uncharacterized protein conserved in bacteria:Carbohydrate transport and metabolism:Coenzyme transport and metabolism:Lipid transport and metabolism:Transcription:Replication, recombination and repair:Cell wall/membrane/envelope biogenesis:Posttranslational modification, protein turnover, chaperones:Inorganic ion transport and metabolism:Purine metabolism:Tryptophan metabolism:Glyoxylate and dicarboxylate metabolism:Methane metabolism:Porphyrin and chlorophyll metabolism:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:General function prediction only:Function unknown:hemH:glcD:efflux_EmrB:arsC_related:Poorly characterized:Carbohydrate Metabolism:Energy Metabolism:Nucleotide Metabolism:Amino Acid Metabolism:Metabolism of Cofactors and Vitamins:Global:Metabolism:Energy metabolism:Other:Regulatory functions:DNA interactions:Transport and binding proteins:Other:Biosynthesis of cofactors, prosthetic groups, and carriers:Heme, porphyrin, and cobalamin:Information storage and processing:Cellular processes and signaling:Metabolism:Metabolism" 248 "Dihydrofolate reductase:Signal transduction histidine kinase:Cation/multidrug efflux pump:Predicted hydrolase (HAD superfamily):ABC-type multidrug transport system, ATPase component:Flagellar motor component:Predicted transcriptional regulators:Type II secretory pathway, pullulanase PulA and related glycosidases:Acetyltransferases, including N-acetylases of ribosomal proteins:Methylase involved in ubiquinone/menaquinone biosynthesis:Sugar phosphate permease:Carbohydrate transport and metabolism:Coenzyme transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:Cell motility:Histidine metabolism:Tyrosine metabolism:Selenocompound metabolism:Polycyclic aromatic hydrocarbon degradation:Microbial metabolism in diverse environments:Two-component system:Bacterial chemotaxis:Flagellar assembly:General function prediction only:Signal transduction mechanisms:LPXTG_anchor:HAD-SF-IA-v1:pulA_typeI:Defense mechanisms:Information storage and processing:Other:Cell envelope:Enzymes of unknown specificity:Unknown function:Metabolism:Metabolism:Global:Cell Motility:Cellular Processes:Signal Transduction:Environmental Information Processing:Xenobiotics Biodegradation and Metabolism:Metabolism of Other Amino Acids:Metabolism:Amino Acid Metabolism:Poorly characterized:Cellular processes and signaling" 249 "Pyrroline-5-carboxylate reductase:Predicted DNA modification methylase:Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs:Lysine efflux permease:Transcriptional regulator:Arabinose efflux permease:Uncharacterized protein conserved in bacteria:Predicted ATPase:Amino acid transport and metabolism:Carbohydrate transport and metabolism:Transcription:Replication, recombination and repair:Arginine and proline metabolism:Metabolic pathways:Biosynthesis of secondary metabolites:General function prediction only:Function unknown:proC:efflux_Bcr_CflA:Information storage and processing:Amino Acid Metabolism:Metabolism:Poorly characterized:Metabolism:Glutamate family:Amino acid biosynthesis:Metabolism:Global" 250 "Energy production and conversion:Molecular chaperone (small heat shock protein):Thymidine phosphorylase:Malic enzyme:Cytidine deaminase:Predicted divalent heavy-metal cations transporter:Amino acid transporters:Carbamate kinase:Glycerophosphoryl diester phosphodiesterase:NAD-dependent aldehyde dehydrogenases:Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs:Phosphatidylserine synthase:Phosphotransferase system cellobiose-specific component IIC:Glycosyl transferases, related to UDP-glucuronosyltransferase:Arylamine N-acetyltransferase:Arginine deiminase:Amino acid transport and metabolism:Nucleotide transport and metabolism:Carbohydrate transport and metabolism:Lipid transport and metabolism:Transcription:Posttranslational modification, protein turnover, chaperones:Inorganic ion transport and metabolism:Purine metabolism:Pyrimidine metabolism:Glycine serine and threonine metabolism:Cysteine and methionine metabolism:Valine leucine and isoleucine degradation:Arginine and proline metabolism:Bisphenol degradation:beta-Alanine metabolism:Glutathione metabolism:Inositol phosphate metabolism:Glycerophospholipid metabolism:Pyruvate metabolism:Aminobenzoate degradation:Propanoate metabolism:Nitrogen metabolism:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:Two-component system:Phosphotransferase system (PTS):Secondary metabolites biosynthesis, transport and catabolism:lacE:pssA:arcC:2A0302:arcA:cyt_deam_tetra:MGT:MMSDH:Y_phosphoryl:Signal transduction:PTS:Information storage and processing:Cellular processes and signaling:Metabolism:Toxin production and resistance:Cellular processes:Amino acids, peptides and amines:Transport and binding proteins:Salvage of nucleosides and nucleotides:Other:Purines, pyrimidines, nucleosides, and nucleotides:Biosynthesis:Fatty acid and phospholipid metabolism:Amino acids and amines:Energy metabolism:Metabolism:Metabolism:Global:Signal Transduction:Membrane Transport:Environmental Information Processing:Xenobiotics Biodegradation and Metabolism:Metabolism of Other Amino Acids:Amino Acid Metabolism:Nucleotide Metabolism:Lipid Metabolism:Energy Metabolism:Carbohydrate Metabolism" 251 "Ribosomal protein S9:Ribosomal protein S15P/S13E:Ribosomal protein L7/L12:Ribosomal protein L28:Ribosomal protein S16:Ribosomal protein S18:Ribosomal protein L31:Ribosomal protein S20:Ribosomal protein L20:Ribosomal protein L19:Ribosomal protein S4 and related proteins:Predicted RNA-binding protein (contains KH domain):Preprotein translocase subunit YajC:Uncharacterized protein conserved in bacteria:Translation, ribosomal structure and biogenesis:Ribosome:Protein export:Bacterial secretion system:General function prediction only:Function unknown:S16:L28:S20:L31:S18:yajC:L12:S15_bact:rpsD_bact:rplS_bact:rplT_bact:Intracellular trafficking, secretion, and vesicular transport:Genetic Information Processing:Poorly characterized:Cellular processes and signaling:Information storage and processing:Protein and peptide secretion and trafficking:Protein fate:Ribosomal proteins: synthesis and modification:Protein synthesis:Membrane Transport:Environmental Information Processing:Folding Sorting and Degradation:Translation" 252 "Energy production and conversion:3-methyladenine DNA glycosylase/8-oxoguanine DNA glycosylase:NAD-dependent DNA ligase (contains BRCT domain type II):Lactoylglutathione lyase and related lyases:NAD/FAD-utilizing enzyme apparently involved in cell division:Kef-type K+ transport systems, membrane components:Signal recognition particle GTPase:Glycerol kinase:Coproporphyrinogen III oxidase and related Fe-S oxidoreductases:Signal transduction histidine kinase:Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain:Predicted ATPase or kinase:Predicted sulfurtransferase:Predicted nucleoside-diphosphate sugar epimerase:ABC-type multidrug transport system, ATPase and permease components:Recombinational DNA repair protein (RecF pathway):DNA replication protein:Zn-dependent proteases:DNA polymerase III, gamma/tau subunits:Signal transduction histidine kinase regulating citrate/malate metabolism:Replication initiation/membrane attachment protein:Response regulator of citrate/malate metabolism:Uncharacterized protein conserved in bacteria:Cell cycle control, cell division, chromosome partitioning:Amino acid transport and metabolism:Coenzyme transport and metabolism:Transcription:Replication, recombination and repair:Inorganic ion transport and metabolism:Purine metabolism:Pyrimidine metabolism:Glycerolipid metabolism:Porphyrin and chlorophyll metabolism:Metabolic pathways:Biosynthesis of secondary metabolites:Two-component system:DNA replication:Protein export:Bacterial secretion system:Base excision repair:Nucleotide excision repair:Mismatch repair:Homologous recombination:General function prediction only:Function unknown:Signal transduction mechanisms:gidA:HI0065_YjeE:sensory_box:hemN_rel:dnlj:reco:ffh:glycerol_kin:yfcH:dnaX_nterm:Intracellular trafficking, secretion, and vesicular transport:Defense mechanisms:Information storage and processing:Heme, porphyrin, and cobalamin:Biosynthesis of cofactors, prosthetic groups, and carriers:Enzymes of unknown specificity:Unknown function:Conserved:Hypothetical proteins:Protein and peptide secretion and trafficking:Protein fate:tRNA and rRNA base modification:Protein synthesis:DNA replication, recombination, and repair:DNA metabolism:Small molecule interactions:Regulatory functions:Other:Energy metabolism:Metabolism:Metabolism:Global:Signal Transduction:Membrane Transport:Environmental Information Processing:Replication and Repair:Folding Sorting and Degradation:Genetic Information Processing:Metabolism of Cofactors and Vitamins:Nucleotide Metabolism:Poorly characterized:Lipid Metabolism:Metabolism:Cellular processes and signaling" 253 "Methionyl-tRNA formyltransferase:ABC-type dipeptide/oligopeptide/nickel transport systems, permease components:Predicted membrane protein:Lysophospholipase:Amino acid transport and metabolism:Lipid transport and metabolism:Translation, ribosomal structure and biogenesis:Inorganic ion transport and metabolism:Glycerophospholipid metabolism:One carbon pool by folate:Aminoacyl-tRNA biosynthesis:Function unknown:yihY_not_rbn:spore_YhcN_YlaJ:General:Lipid Metabolism:Metabolism of Cofactors and Vitamins:Genetic Information Processing:Translation:Cellular processes:Sporulation and germination:Unknown function:Metabolism:Information storage and processing:Metabolism:Poorly characterized" 254 "Energy production and conversion:Deoxyribodipyrimidine photolyase:Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily):Predicted phosphoesterase:Signal transduction histidine kinase:Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain:Panthothenate kinase:Uncharacterized low-complexity proteins:Beta-lactamase class C and other penicillin binding proteins:Uncharacterized conserved protein:Glycosyl transferases, related to UDP-glucuronosyltransferase:Xanthine/uracil permeases:Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog):Nucleotide transport and metabolism:Carbohydrate transport and metabolism:Coenzyme transport and metabolism:Transcription:Replication, recombination and repair:Pyrimidine metabolism:Metabolic pathways:General function prediction only:Function unknown:Signal transduction mechanisms:MGT:Defense mechanisms:Metabolism:Poorly characterized:Metabolism:Cellular processes and signaling:Information storage and processing:Toxin production and resistance:Cellular processes:Metabolism:Global:Nucleotide Metabolism" 255 "Single-stranded DNA-binding protein:ABC-type antimicrobial peptide transport system, ATPase component:Uncharacterized conserved protein:Phage head maturation protease:Replication, recombination and repair:DNA replication:Mismatch repair:Homologous recombination:General function prediction only:Function unknown:ssb:proheadase_HK97:maj_tail_phi13:Defense mechanisms:Mobile and extrachromosomal element functions:Replication and Repair:DNA metabolism:DNA replication, recombination, and repair:Protein fate:Other:Genetic Information Processing:Prophage functions:Information storage and processing:Cellular processes and signaling:Poorly characterized" 256 "Energy production and conversion:Signal transduction histidine kinase:Permeases of the drug/metabolite transporter (DMT) superfamily:Membrane carboxypeptidase (penicillin-binding protein):Glutathionylspermidine synthase:Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases):Putative threonine efflux protein:Amidases related to nicotinamidase:Ribonucleases G and E:Beta-lactamase class C and other penicillin binding proteins:Glycosyl transferases, related to UDP-glucuronosyltransferase:Transcriptional regulators:Predicted membrane protein:Uncharacterized protein conserved in bacteria:Amino acid transport and metabolism:Carbohydrate transport and metabolism:Lipid transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:Cell wall/membrane/envelope biogenesis:Pentose phosphate pathway:Fatty acid biosynthesis:Glutathione metabolism:Biosynthesis of unsaturated fatty acids:Metabolic pathways:Microbial metabolism in diverse environments:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:Function unknown:Signal transduction mechanisms:RNaseEG:MGT:PBP_1a_fam:spore_ger_x_C:spore_ysxE:M6dom_TIGR03296:Defense mechanisms:Metabolism:Carbohydrate Metabolism:Lipid Metabolism:Metabolism of Other Amino Acids:Global:Metabolism:Transcription:Degradation of RNA:Cellular processes:Toxin production and resistance:Sporulation and germination:Cell envelope:Biosynthesis and degradation of murein sacculus and peptidoglycan:Information storage and processing:Cellular processes and signaling:Metabolism:Poorly characterized" 257 "Energy production and conversion:Arginase/agmatinase/formimionoglutamate hydrolase, arginase family:S-adenosylmethionine synthetase:Site-specific DNA methylase:Glycine/D-amino acid oxidases (deaminating):Uncharacterized conserved protein:Putative threonine efflux protein:Na+/phosphate symporter:Recombinational DNA repair protein (RecF pathway):Uncharacterized conserved protein:D-alanyl-D-alanine carboxypeptidase:Uncharacterized conserved protein:Zn-dependent dipeptidase, microsomal dipeptidase homolog:Predicted secreted acid phosphatase:Arabinose efflux permease:Na+/citrate symporter:Superfamily II DNA/RNA helicase required for DNA uptake (late competence protein):Predicted lipoprotein involved in nitrous oxide reduction:Uncharacterized protein conserved in bacteria:Amino acid transport and metabolism:Carbohydrate transport and metabolism:Coenzyme transport and metabolism:Replication, recombination and repair:Cell wall/membrane/envelope biogenesis:Inorganic ion transport and metabolism:Cysteine and methionine metabolism:Arginine and proline metabolism:Selenocompound metabolism:Peptidoglycan biosynthesis:Metabolic pathways:Biosynthesis of secondary metabolites:Two-component system:Homologous recombination:General function prediction only:Function unknown:reco:dcm:NaPi_cotrn_rel:metK:agmatinase:lipo_e_P4:Ku_bact:Poorly characterized:Metabolism:Cellular processes and signaling:Information storage and processing:Pyridine nucleotides:Biosynthesis of cofactors, prosthetic groups, and carriers:Cations and iron carrying compounds:Transport and binding proteins:DNA replication, recombination, and repair:DNA metabolism:Other:Central intermediary metabolism:Metabolism:Metabolism:Global:Signal Transduction:Environmental Information Processing:Replication and Repair:Genetic Information Processing:Glycan Biosynthesis and Metabolism:Metabolism of Other Amino Acids:Amino Acid Metabolism" 258 "Xaa-Pro aminopeptidase:Uncharacterized conserved protein:Predicted epimerase, PhzC/PhzF homolog:Protein-tyrosine-phosphatase:Uridine kinase:Predicted Zn-dependent peptidases:Oligoendopeptidase F:Sortase and related acyltransferases:Hemolysins and related proteins containing CBS domains:Acetyltransferases, including N-acetylases of ribosomal proteins:Sec-independent protein secretion pathway components:Predicted metal-dependent hydrolase:Transcriptional regulator/sugar kinase:Molybdenum cofactor biosynthesis enzyme:Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains:Amino acid transport and metabolism:Nucleotide transport and metabolism:Carbohydrate transport and metabolism:Coenzyme transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:Cell wall/membrane/envelope biogenesis:Glycolysis / Gluconeogenesis:Galactose metabolism:Pyrimidine metabolism:Phosphonate and phosphinate metabolism:Starch and sucrose metabolism:Amino sugar and nucleotide sugar metabolism:Streptomycin biosynthesis:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:Protein export:Bacterial secretion system:Sulfur relay system:General function prediction only:Function unknown:Signal transduction mechanisms:pepF:PhzF_family:tatAE:moaA:trp_arylform:Intracellular trafficking, secretion, and vesicular transport:Information storage and processing:Molybdopterin:Biosynthesis of cofactors, prosthetic groups, and carriers:Toxin production and resistance:Cellular processes:Degradation of proteins, peptides, and glycopeptides:Protein and peptide secretion and trafficking:Protein fate:Amino acids and amines:Energy metabolism:Metabolism:Metabolism:Global:Membrane Transport:Environmental Information Processing:Folding Sorting and Degradation:Genetic Information Processing:Biosynthesis of Other Secondary Metabolites:Metabolism of Other Amino Acids:Nucleotide Metabolism:Poorly characterized:Carbohydrate Metabolism:Metabolism:Cellular processes and signaling" 259 "Energy production and conversion:Predicted N6-adenine-specific DNA methylase:Shikimate 5-dehydrogenase:Glycerol-3-phosphate dehydrogenase:F0F1-type ATP synthase, subunit a:SAM-dependent methyltransferases:F0F1-type ATP synthase, subunit b:F0F1-type ATP synthase, delta subunit (mitochondrial oligomycin sensitivity protein):Uncharacterized homolog of plant Iojap protein:Nicotinic acid mononucleotide adenylyltransferase:Predicted GTPases:Predicted RNA-binding protein containing KH domain, possibly ribosomal protein:Predicted HD superfamily hydrolase involved in NAD metabolism:Amino acid transport and metabolism:Coenzyme transport and metabolism:Translation, ribosomal structure and biogenesis:Replication, recombination and repair:Oxidative phosphorylation:Histidine metabolism:Tyrosine metabolism:Phenylalanine tyrosine and tryptophan biosynthesis:Selenocompound metabolism:Glycerophospholipid metabolism:Polycyclic aromatic hydrocarbon degradation:Nicotinate and nicotinamide metabolism:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:Function unknown:iojap_ybeB:cyt_tran_rel:small_GTP:RNA_bind_YhbY:HDIG:aroE:ATP_synt_6_or_A:ATP_synt_b:ATP_synt_delta:ATP_synt_c:General:Unknown function:ATP-proton motive force interconversion:Energy metabolism:Metabolism:Global:Metabolism:Xenobiotics Biodegradation and Metabolism:Metabolism of Cofactors and Vitamins:Metabolism of Other Amino Acids:Amino Acid Metabolism:Lipid Metabolism:Information storage and processing:Energy Metabolism:Metabolism:Poorly characterized:Aromatic amino acid family:Amino acid biosynthesis" 260 "Geranylgeranyl pyrophosphate synthase:Peptide methionine sulfoxide reductase:N6-adenine-specific methylase:Bacterial cell division membrane protein:Uncharacterized protein conserved in bacteria:Transcriptional regulator:Predicted kinase related to dihydroxyacetone kinase:Transcriptional regulators:4-diphosphocytidyl-2C-methyl-D-erythritol 2-phosphate synthase:Arginine/lysine/ornithine decarboxylases:Methylase involved in ubiquinone/menaquinone biosynthesis:Uncharacterized protein conserved in bacteria:Membrane-bound metallopeptidase:Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain:Signal transduction histidine kinase:Cell cycle control, cell division, chromosome partitioning:Amino acid transport and metabolism:Coenzyme transport and metabolism:Lipid transport and metabolism:Transcription:Replication, recombination and repair:Posttranslational modification, protein turnover, chaperones:Ubiquinone and other terpenoid-quinone biosynthesis:Arginine and proline metabolism:Terpenoid backbone biosynthesis:Metabolic pathways:Biosynthesis of secondary metabolites:General function prediction only:Function unknown:Signal transduction mechanisms:TIGR00095:ispE:sensory_box:msrA:DegV:MenG_MenH_UbiE:GerC3_HepT:YloV:Menaquinone and ubiquinone:Amino Acid Metabolism:Metabolism of Cofactors and Vitamins:Metabolism of Terpenoids and Polyketides:Global:Metabolism:Regulatory functions:Small molecule interactions:Protein synthesis:tRNA and rRNA base modification:Cellular processes:Adaptations to atypical conditions:Unknown function:General:Biosynthesis of cofactors, prosthetic groups, and carriers:Other:Metabolism:Information storage and processing:Cellular processes and signaling:Metabolism:Poorly characterized" 261 "Zn-dependent protease with chaperone function:rRNA methylases:Transcriptional regulator:Signal transduction histidine kinase:Predicted transcriptional regulators:DNA polymerase III, epsilon subunit and related 3'-5' exonucleases:Predicted transcriptional regulator, consists of a Zn-ribbon and ATP-cone domains:Predicted transcriptional regulators:Esterase/lipase:Transcriptional regulators:Uncharacterized conserved protein:Deoxycytidylate deaminase:Predicted Zn-dependent protease:Sugar diacid utilization regulator:Uncharacterized protein conserved in bacteria:Transcriptional regulator, effector-binding domain/component:Signal transduction histidine kinase:Nucleotide transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:Replication, recombination and repair:Posttranslational modification, protein turnover, chaperones:Purine metabolism:Pyrimidine metabolism:Metabolic pathways:Two-component system:DNA replication:Mismatch repair:Homologous recombination:General function prediction only:Function unknown:Signal transduction mechanisms:sensory_box:TIGR00244:IMPACT_YIGZ:dnaq:excise:ComEB:Regulatory functions:Metabolism:Global:Signal Transduction:Environmental Information Processing:Metabolism:Replication and Repair:Genetic Information Processing:Information storage and processing:Nucleotide Metabolism:Cellular processes and signaling:Metabolism:Poorly characterized:General:Unknown function:Degradation of DNA:DNA metabolism:Small molecule interactions:DNA interactions" 262 "Energy production and conversion:Cysteine synthase:Predicted tRNA(5-methylaminomethyl-2-thiouridylate) methyltransferase, contains the PP-loop ATPase domain:Thioredoxin reductase:Predicted hydrolases of the HAD superfamily:Superoxide dismutase:Cystathionine beta-lyases/cystathionine gamma-synthases:Predicted transcriptional regulators:ABC-type amino acid transport system, permease component:Nucleoside phosphorylase:Nitroreductase:ABC-type amino acid transport/signal transduction systems, periplasmic component/domain:ABC-type polar amino acid transport system, ATPase component:Uncharacterized conserved protein:D-Tyr-tRNAtyr deacylase:Predicted Na+/dicarboxylate symporter:Transcriptional regulators:LuxS protein involved in autoinducer AI2 synthesis:Predicted transcriptional regulator:Methylase involved in ubiquinone/menaquinone biosynthesis:Uncharacterized protein conserved in bacteria:Amino acid transport and metabolism:Nucleotide transport and metabolism:Coenzyme transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:Posttranslational modification, protein turnover, chaperones:Inorganic ion transport and metabolism:Pyrimidine metabolism:Cysteine and methionine metabolism:Tyrosine metabolism:Benzoate degradation:Selenocompound metabolism:Naphthalene degradation:Aminobenzoate degradation:Ethylbenzene degradation:Limonene and pinene degradation:Nitrogen metabolism:Sulfur metabolism:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:Sulfur relay system:General function prediction only:Function unknown:Signal transduction mechanisms:Cof-subfamily:TIGR00256:trmU:rrf2_super:cysKM:MTA/SAH-Nsdase:HEQRo_perm_3TM:Bthiol_YpdA:tRNA and rRNA base modification:tRNA aminoacylation:Protein synthesis:Salvage of nucleosides and nucleotides:Purines, pyrimidines, nucleosides, and nucleotides:Metabolism:Global:Metabolism:Folding Sorting and Degradation:Genetic Information Processing:Xenobiotics Biodegradation and Metabolism:Metabolism of Terpenoids and Polyketides:Metabolism of Other Amino Acids:Amino Acid Metabolism:Nucleotide Metabolism:General:Energy Metabolism:Amino acid biosynthesis:Serine family:Information storage and processing:Cellular processes and signaling:Metabolism:Poorly characterized:Enzymes of unknown specificity:Unknown function:Amino acids, peptides and amines:Transport and binding proteins" 263 "Nucleoside-diphosphate-sugar epimerases:ABC-type Fe3+-hydroxamate transport system, periplasmic component:Signal transduction histidine kinase:Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain:UDP-glucose 4-epimerase:ABC-type multidrug transport system, ATPase component:Transcriptional regulators of sugar metabolism:Predicted phosphohydrolases:Phosphotransferase system cellobiose-specific component IIC:Uncharacterized conserved protein, contains double-stranded beta-helix domain:Arginine/lysine/ornithine decarboxylases:Type II secretory pathway, pseudopilin PulG:AraC-type DNA-binding domain-containing proteins:Sugar phosphate permease:Uncharacterized conserved protein, contains S4-like domain:Predicted membrane protein:Homogentisate 1,2-dioxygenase:Predicted membrane protein:Uncharacterized protein conserved in bacteria:Signal transduction histidine kinase involved in nitrogen fixation and metabolism regulation:Alpha-tubulin suppressor and related RCC1 domain-containing proteins:Cell cycle control, cell division, chromosome partitioning:Amino acid transport and metabolism:Carbohydrate transport and metabolism:Transcription:Cell wall/membrane/envelope biogenesis:Cell motility:Inorganic ion transport and metabolism:Galactose metabolism:Arginine and proline metabolism:Tyrosine metabolism:Amino sugar and nucleotide sugar metabolism:Styrene degradation:Metabolic pathways:Microbial metabolism in diverse environments:ABC transporters:Two-component system:Phosphotransferase system (PTS):Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:Function unknown:Signal transduction mechanisms:cello_pts_IIC:galE:T_den_put_tspse:IV_pilin_GFxxxE:B_an_ocin:TIGR03943:Intracellular trafficking, secretion, and vesicular transport:Defense mechanisms:Cytoskeleton:Poorly characterized:Carbohydrate Metabolism:Amino Acid Metabolism:Xenobiotics Biodegradation and Metabolism:Environmental Information Processing:Membrane Transport:Signal Transduction:Global:Metabolism:Energy metabolism:Sugars:Protein fate:Protein and peptide secretion and trafficking:Cellular processes:Toxin production and resistance:Signal transduction:PTS:Information storage and processing:Cellular processes and signaling:Metabolism:Metabolism" 264 "Energy production and conversion:Arginase/agmatinase/formimionoglutamate hydrolase, arginase family:Acetyltransferase (isoleucine patch superfamily):Acetyltransferases:Predicted hydrolases of the HAD superfamily:Predicted dehydrogenase:3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratases:Na+/H+-dicarboxylate symporters:Uncharacterized conserved protein:Putative enzyme of poly-gamma-glutamate biosynthesis (capsule formation):Signal transduction histidine kinase:Uncharacterized protein containing a divergent version of the methyl-accepting chemotaxis-like domain:Genetic competence transcription factor:Amino acid transport and metabolism:Lipid transport and metabolism:Transcription:Cell wall/membrane/envelope biogenesis:Fatty acid biosynthesis:Arginine and proline metabolism:Tyrosine metabolism:Benzoate degradation:Pyruvate metabolism:Naphthalene degradation:Aminobenzoate degradation:Ethylbenzene degradation:Limonene and pinene degradation:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:Two-component system:General function prediction only:Function unknown:Signal transduction mechanisms:Cof-subfamily:rocF_arginase:mal_quin_oxido:fabZ:B_thiol_YtxJ:Enzymes of unknown specificity:Unknown function:Biosynthesis:Fatty acid and phospholipid metabolism:Metabolism:Global:TCA cycle:Energy metabolism:Signal Transduction:Environmental Information Processing:Metabolism:Xenobiotics Biodegradation and Metabolism:Metabolism of Terpenoids and Polyketides:Amino Acid Metabolism:Lipid Metabolism:Information storage and processing:Carbohydrate Metabolism:Cellular processes and signaling:Metabolism:Poorly characterized" 265 "Argininosuccinate lyase:Zn-dependent protease with chaperone function:Predicted choline kinase involved in LPS biosynthesis:Signal transduction histidine kinase:FOG: Ankyrin repeat:Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain:Parvulin-like peptidyl-prolyl isomerase:Predicted SAM-dependent methyltransferases:Uncharacterized conserved protein:Preprotein translocase subunit SecG:S-adenosylmethionine decarboxylase:Beta-lactamase class C and other penicillin binding proteins:Signal transduction histidine kinase regulating phosphoglycerate transport system:Uncharacterized protein conserved in bacteria:Amino acid transport and metabolism:Transcription:Cell wall/membrane/envelope biogenesis:Posttranslational modification, protein turnover, chaperones:Alanine aspartate and glutamate metabolism:Cysteine and methionine metabolism:Arginine and proline metabolism:Metabolic pathways:Biosynthesis of secondary metabolites:Two-component system:Protein export:Bacterial secretion system:General function prediction only:Function unknown:Signal transduction mechanisms:secG:argH:SAM_DCase_Bsu:Intracellular trafficking, secretion, and vesicular transport:Defense mechanisms:Information storage and processing:Amino Acid Metabolism:Genetic Information Processing:Folding Sorting and Degradation:Environmental Information Processing:Membrane Transport:Signal Transduction:Global:Metabolism:Central intermediary metabolism:Polyamine biosynthesis:Protein fate:Protein and peptide secretion and trafficking:Amino acid biosynthesis:Glutamate family:Metabolism:Cellular processes and signaling:Metabolism:Poorly characterized" 266 "Energy production and conversion:Uracil phosphoribosyltransferase:Acetate kinase:IMP dehydrogenase/GMP reductase:Cytosine/adenosine deaminases:Predicted sugar phosphatases of the HAD superfamily:Sulfate permease and related transporters (MFS superfamily):cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases:Membrane-associated phospholipid phosphatase:Methyl-accepting chemotaxis protein:Acetyltransferases, including N-acetylases of ribosomal proteins:Sporulation control protein:Flagellar basal body rod protein:Nucleotide transport and metabolism:Carbohydrate transport and metabolism:Lipid transport and metabolism:Translation, ribosomal structure and biogenesis:Cell motility:Inorganic ion transport and metabolism:Purine metabolism:Pyrimidine metabolism:Tyrosine metabolism:Benzoate degradation:Taurine and hypotaurine metabolism:Glycerophospholipid metabolism:Pyruvate metabolism:Naphthalene degradation:Aminobenzoate degradation:Propanoate metabolism:Ethylbenzene degradation:Methane metabolism:Carbon fixation pathways in prokaryotes:Limonene and pinene degradation:Metabolic pathways:Microbial metabolism in diverse environments:Two-component system:Bacterial chemotaxis:Flagellar assembly:General function prediction only:Signal transduction mechanisms:ackA:upp:GMP_reduct_2:HAD-SF-IIA-hyp2:FlgEFG_subfam:Salvage of nucleosides and nucleotides:Carbohydrate Metabolism:Energy Metabolism:Lipid Metabolism:Nucleotide Metabolism:Amino Acid Metabolism:Metabolism of Other Amino Acids:Metabolism of Terpenoids and Polyketides:Xenobiotics Biodegradation and Metabolism:Environmental Information Processing:Signal Transduction:Cellular Processes:Cell Motility:Global:Metabolism:Energy metabolism:Fermentation:Purines, pyrimidines, nucleosides, and nucleotides:Nucleotide and nucleoside interconversions:Metabolism:Unknown function:Enzymes of unknown specificity:Information storage and processing:Cellular processes and signaling:Metabolism:Poorly characterized" 267 "Dihydrofolate reductase:Thioredoxin reductase:Membrane proteins related to metalloendopeptidases:Molybdopterin converting factor, small subunit:Uncharacterized protein conserved in bacteria:Predicted integral membrane protein:Coenzyme transport and metabolism:Cell wall/membrane/envelope biogenesis:Posttranslational modification, protein turnover, chaperones:Glycine serine and threonine metabolism:Metabolic pathways:Sulfur relay system:Function unknown:moaD:Cellular processes and signaling:Amino Acid Metabolism:Genetic Information Processing:Folding Sorting and Degradation:Global:Metabolism:Biosynthesis of cofactors, prosthetic groups, and carriers:Molybdopterin:Metabolism:Metabolism:Poorly characterized" 268 "Uncharacterized conserved protein:Superfamily II DNA and RNA helicases:DNA polymerase III, alpha subunit:Exopolyphosphatase-related proteins:Signal transduction histidine kinase:Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain:Predicted transcriptional regulators:Transcriptional regulator:Predicted phosphohydrolases:Phosphatidylserine/phosphatidylglycerophosphate/cardiolipin synthases and related enzymes:Acyl-CoA hydrolase:Ketopantoate reductase:Uncharacterized proteins, LmbE homologs:Uncharacterized conserved protein:Arabinose efflux permease:Negative regulator of genetic competence, sporulation and motility:Uncharacterized conserved protein:Carbohydrate transport and metabolism:Coenzyme transport and metabolism:Lipid transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:Replication, recombination and repair:Cell motility:Posttranslational modification, protein turnover, chaperones:Purine metabolism:Pyrimidine metabolism:Glycerophospholipid metabolism:Pantothenate and CoA biosynthesis:Limonene and pinene degradation:Biosynthesis of unsaturated fatty acids:Metabolic pathways:Biosynthesis of secondary metabolites:RNA degradation:DNA replication:Mismatch repair:Homologous recombination:General function prediction only:Function unknown:Signal transduction mechanisms:polc:recQ_fam:apbA_panE:thiol_BshB2:Metabolism:Cellular processes and signaling:Information storage and processing:Glutathione and analogs:Pantothenate and coenzyme A:Biosynthesis of cofactors, prosthetic groups, and carriers:DNA replication, recombination, and repair:DNA metabolism:Metabolism:Metabolism:Global:Replication and Repair:Folding Sorting and Degradation:Genetic Information Processing:Metabolism of Terpenoids and Polyketides:Metabolism of Cofactors and Vitamins:Nucleotide Metabolism:Poorly characterized:Lipid Metabolism" 269 "Predicted GTPase, probable translation factor:Predicted EndoIII-related endonuclease:Protein chain release factor A:Phosphate/sulphate permeases:Biotin carboxylase:Membrane GTPase LepA:DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32):2-methylthioadenine synthetase:Preprotein translocase subunit YidC:Transcription termination factor:Predicted GTPases:Phosphate transport regulator (distant homolog of PhoU):Putative primosome component and related proteins:Lipid transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:Replication, recombination and repair:Cell wall/membrane/envelope biogenesis:Inorganic ion transport and metabolism:Fatty acid biosynthesis:Pyruvate metabolism:Propanoate metabolism:Carbon fixation pathways in prokaryotes:Metabolic pathways:Biosynthesis of secondary metabolites:RNA degradation:RNA polymerase:Protein export:Bacterial secretion system:Base excision repair:General function prediction only:prfA:TIGR00089:TIGR00092:small_GTP:accC:rho:nth:DnaD_dom:RpoD_Cterm:yidC_oxa1_cterm:GTPase_YlqF:Intracellular trafficking, secretion, and vesicular transport:Prophage functions:Carbohydrate Metabolism:Energy Metabolism:Lipid Metabolism:Genetic Information Processing:Transcription:Folding Sorting and Degradation:Replication and Repair:Environmental Information Processing:Membrane Transport:Global:Metabolism:Fatty acid and phospholipid metabolism:Biosynthesis:DNA metabolism:DNA replication, recombination, and repair:Transcription:Transcription factors:Protein synthesis:Other:Translation factors:Protein fate:Protein and peptide secretion and trafficking:Mobile and extrachromosomal element functions:Metabolism:Unknown function:General:Information storage and processing:Cellular processes and signaling:Metabolism:Poorly characterized" 270 "Glutamyl- and glutaminyl-tRNA synthetases:Pentose-5-phosphate-3-epimerase:EMAP domain:Glucose-6-phosphate isomerase:FKBP-type peptidyl-prolyl cis-trans isomerase (trigger factor):Predicted Zn-dependent peptidases:Signal transduction histidine kinase:Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain:Transcriptional regulators:Uncharacterized protein conserved in bacteria:Uncharacterized protein conserved in bacteria:Carbohydrate transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:Posttranslational modification, protein turnover, chaperones:Glycolysis / Gluconeogenesis:Pentose phosphate pathway:Pentose and glucuronate interconversions:Lysine degradation:Starch and sucrose metabolism:Amino sugar and nucleotide sugar metabolism:Biotin metabolism:Aminoacyl-tRNA biosynthesis:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:General function prediction only:Function unknown:Signal transduction mechanisms:tig:gltX_bact:rpe:ccpA:Cellular processes and signaling:Carbohydrate Metabolism:Amino Acid Metabolism:Metabolism of Cofactors and Vitamins:Genetic Information Processing:Translation:Global:Metabolism:Energy metabolism:Pentose phosphate pathway:Regulatory functions:DNA interactions:Protein synthesis:tRNA aminoacylation:Protein fate:Protein folding and stabilization:Information storage and processing:Metabolism:Metabolism:Poorly characterized" 271 "Energy production and conversion:ABC-type Fe3+-siderophore transport system, permease component:ABC-type Fe3+-hydroxamate transport system, periplasmic component:Flavodoxins:Peptide arylation enzymes:Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases):ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components:Isochorismate synthase:Uncharacterized enzyme involved in biosynthesis of extracellular polysaccharides:Coenzyme transport and metabolism:Lipid transport and metabolism:Inorganic ion transport and metabolism:Ubiquinone and other terpenoid-quinone biosynthesis:Biosynthesis of siderophore group nonribosomal peptides:Metabolic pathways:Biosynthesis of secondary metabolites:ABC transporters:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:isochor_syn:flav_short:DHB_AMP_lig:srtB_target:Cations and iron carrying compounds:Metabolism of Cofactors and Vitamins:Metabolism of Terpenoids and Polyketides:Environmental Information Processing:Membrane Transport:Global:Metabolism:Energy metabolism:Electron transport:Transport and binding proteins:Metabolism:Biosynthesis of cofactors, prosthetic groups, and carriers:Menaquinone and ubiquinone:Metabolism:Poorly characterized" 272 "Predicted S-adenosylmethionine-dependent methyltransferase:Uncharacterized membrane protein (homolog of Drosophila rhomboid):Cation/multidrug efflux pump:Gamma-aminobutyrate permease and related permeases:Predicted transcriptional regulators:Uncharacterized conserved protein:Inosine-uridine nucleoside N-ribohydrolase:Uncharacterized conserved protein:Chitinase:Amino acid transport and metabolism:Nucleotide transport and metabolism:Carbohydrate transport and metabolism:Transcription:Purine metabolism:Amino sugar and nucleotide sugar metabolism:Nicotinate and nicotinamide metabolism:Metabolic pathways:General function prediction only:Function unknown:spore_V_AC:spore_YyaC:spore_yqfC:docking_ocin:TIGR04086_membr:Defense mechanisms:Cellular processes and signaling:Carbohydrate Metabolism:Nucleotide Metabolism:Metabolism of Cofactors and Vitamins:Global:Metabolism:Cellular processes:Sporulation and germination:Information storage and processing:Metabolism:Metabolism:Poorly characterized" 273 "Methionyl-tRNA synthetase:Diaminopimelate epimerase:Molybdopterin biosynthesis enzymes:Hypoxanthine-guanine phosphoribosyltransferase:UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase:Predicted transcriptional regulators:ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components:GTPase:Hemolysins and related proteins containing CBS domains:Transcriptional regulator:DNA polymerase III, delta subunit:Predicted membrane protein:Predicted Zn-dependent hydrolases of the beta-lactamase fold:Predicted transcriptional regulator:Membrane protein involved in cytochrome C biogenesis:Site-specific recombinase XerD:Amino acid transport and metabolism:Nucleotide transport and metabolism:Coenzyme transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:Replication, recombination and repair:Cell wall/membrane/envelope biogenesis:Posttranslational modification, protein turnover, chaperones:Inorganic ion transport and metabolism:Purine metabolism:Pyrimidine metabolism:Lysine biosynthesis:Selenocompound metabolism:Glycerolipid metabolism:Terpenoid backbone biosynthesis:Aminoacyl-tRNA biosynthesis:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:DNA replication:Mismatch repair:Homologous recombination:General function prediction only:Function unknown:molyb_syn:small_GTP:metG:DapF:holA:HGPRTase:recomb_XerC:Protein synthesis:DNA replication, recombination, and repair:DNA metabolism:Salvage of nucleosides and nucleotides:Purines, pyrimidines, nucleosides, and nucleotides:Metabolism:Global:Metabolism:Replication and Repair:Translation:Genetic Information Processing:Metabolism of Terpenoids and Polyketides:Metabolism of Other Amino Acids:Amino Acid Metabolism:Nucleotide Metabolism:General:Lipid Metabolism:Amino acid biosynthesis:Aspartate family:Information storage and processing:Cellular processes and signaling:Metabolism:Poorly characterized:Unknown function:tRNA aminoacylation" 274 "Energy production and conversion:Thiol-disulfide isomerase and thioredoxins:Predicted endonuclease involved in recombination (possible Holliday junction resolvase in Mycoplasmas and B. subtilis):Preprotein translocase subunit SecG:Uncharacterized protein conserved in bacteria:Uncharacterized protein conserved in bacteria:Replication, recombination and repair:Posttranslational modification, protein turnover, chaperones:Protein export:Bacterial secretion system:Function unknown:RNAse_H_YqgF:secG:nudix_YtkD:Intracellular trafficking, secretion, and vesicular transport:General:Folding Sorting and Degradation:Environmental Information Processing:Membrane Transport:DNA metabolism:DNA replication, recombination, and repair:Protein fate:Protein and peptide secretion and trafficking:Unknown function:Genetic Information Processing:Information storage and processing:Cellular processes and signaling:Metabolism:Poorly characterized" 275 "Predicted RNA binding protein (contains ribosomal protein S1 domain):Predicted transcriptional regulators:Uncharacterized stress-induced protein:DNA-directed RNA polymerase, subunit K/omega:Predicted hydrolase of the HAD superfamily:Septum formation initiator:Protein required for the initiation of cell division:Predicted small secreted protein:Cell cycle control, cell division, chromosome partitioning:Translation, ribosomal structure and biogenesis:Transcription:Purine metabolism:Pyrimidine metabolism:Metabolic pathways:RNA polymerase:General function prediction only:Function unknown:parB_part:TIGR00255:rpoZ:HAD-SF-IA-v3:ftsL_broad:Hypothetical proteins:Nucleotide Metabolism:Genetic Information Processing:Transcription:Global:Metabolism:Transcription:DNA-dependent RNA polymerase:Cellular processes:Cell division:Metabolism:Conserved:Unknown function:Enzymes of unknown specificity:Information storage and processing:Cellular processes and signaling:Poorly characterized" 276 "Cell wall-associated hydrolases (invasion-associated proteins):ABC-type multidrug transport system, ATPase component:Cold shock proteins:Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase:Outer membrane lipoprotein-sorting protein:Lipid transport and metabolism:Transcription:Cell wall/membrane/envelope biogenesis:ABC transporters:General function prediction only:TIGR00147:staph_tand_hypo:Defense mechanisms:Poorly characterized:Membrane Transport:Unknown function:Enzymes of unknown specificity:Information storage and processing:Cellular processes and signaling:Metabolism:Environmental Information Processing" 277 "Energy production and conversion:Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit:Phosphotransacetylase:Glutamate dehydrogenase/leucine dehydrogenase:Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component, and related enzymes:Cation/multidrug efflux pump:Predicted ATP-dependent protease:Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit:Imidazolonepropionase and related amidohydrolases:Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes:Uncharacterized iron-regulated membrane protein:Butyrate kinase:Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains:Predicted membrane protein:Amino acid transport and metabolism:Transcription:Posttranslational modification, protein turnover, chaperones:Glycolysis / Gluconeogenesis:Citrate cycle (TCA cycle):Glycine serine and threonine metabolism:Valine leucine and isoleucine degradation:Valine leucine and isoleucine biosynthesis:Pyruvate metabolism:Butanoate metabolism:Sulfur metabolism:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:Secondary metabolites biosynthesis, transport and catabolism:Function unknown:Signal transduction mechanisms:sensory_box:lipoamide_DH:thia_yuaJ:P_butyryltrans:butyr_kinase:spore_BofA:spore_lonB:SASP_sspK:Defense mechanisms:Global:Amino Acid Metabolism:Energy Metabolism:Fermentation:Carbohydrate Metabolism:Regulatory functions:Small molecule interactions:Transport and binding proteins:Other:Cellular processes:Sporulation and germination:Information storage and processing:Cellular processes and signaling:Metabolism:Poorly characterized:Energy metabolism:Metabolism:Metabolism" 278 "spore_II_P:spore_ytfJ:M6dom_TIGR03296:Cellular processes:Sporulation and germination" 279 "Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II:Signal transduction histidine kinase:Mannose-6-phosphate isomerase:Predicted transcriptional regulators:Uncharacterized proteins, homologs of microcin C7 resistance protein MccF:Acetyltransferases, including N-acetylases of ribosomal proteins:Beta-lactamase class C and other penicillin binding proteins:Teichoic acid biosynthesis proteins:Acyl-CoA dehydrogenases:Uncharacterized protein involved in propionate catabolism:Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain:FOG: GAF domain:Uncharacterized conserved protein:Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains:Uncharacterized conserved protein:Carbohydrate transport and metabolism:Lipid transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:Cell wall/membrane/envelope biogenesis:Geraniol degradation:Naphthalene degradation:Propanoate metabolism:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:Function unknown:Signal transduction mechanisms:sensory_box:wecG_tagA_cpsF:prpD:Defense mechanisms:Carbohydrate Metabolism:Metabolism:Poorly characterized:Information storage and processing:Metabolism:Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides:Cell envelope:Small molecule interactions:Regulatory functions:Metabolism:Global:Xenobiotics Biodegradation and Metabolism:Metabolism of Terpenoids and Polyketides:Cellular processes and signaling" 280 "Energy production and conversion:Isocitrate/isopropylmalate dehydrogenase:Acetyltransferases, including N-acetylases of ribosomal proteins:Predicted membrane protein:Nucleoside permease:Uncharacterized vancomycin resistance protein:Amino acid transport and metabolism:Nucleotide transport and metabolism:Translation, ribosomal structure and biogenesis:Valine leucine and isoleucine biosynthesis:Metabolic pathways:Biosynthesis of secondary metabolites:Function unknown:leuB:spore_V_AE:Defense mechanisms:Cellular processes and signaling:Amino Acid Metabolism:Global:Metabolism:Cellular processes:Sporulation and germination:Amino acid biosynthesis:Pyruvate family:Information storage and processing:Metabolism:Metabolism:Poorly characterized" 281 "Energy production and conversion:ATPase components of ABC transporters with duplicated ATPase domains:FOG: CBS domain:Amino acid transporters:Phosphoenolpyruvate synthase/pyruvate phosphate dikinase:Permeases of the drug/metabolite transporter (DMT) superfamily:Predicted xylanase/chitin deacetylase:Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain:Predicted hydrolase (HAD superfamily):Imidazolonepropionase and related amidohydrolases:Phosphatidylglycerophosphatase A and related proteins:Predicted membrane protein:ABC-type Na+ efflux pump, permease component:Acetyltransferases, including N-acetylases of ribosomal proteins:Regulators of stationary/sporulation gene expression:Uncharacterized conserved protein:Uncharacterized conserved protein, contains S4-like domain:Uncharacterized protein conserved in bacteria:Amino acid transport and metabolism:Carbohydrate transport and metabolism:Lipid transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:Inorganic ion transport and metabolism:Arginine and proline metabolism:Pyruvate metabolism:Chloroalkane and chloroalkene degradation:Methane metabolism:Carbon fixation pathways in prokaryotes:Metabolic pathways:Microbial metabolism in diverse environments:ABC transporters:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:Function unknown:Signal transduction mechanisms:lp_hng_hel_AbrB:HAD-SF-IA-v1:spo_ytxC:xxxLxxG_by_4:Metabolism:Carbohydrate Metabolism:Energy Metabolism:Amino Acid Metabolism:Xenobiotics Biodegradation and Metabolism:Environmental Information Processing:Membrane Transport:Global:Metabolism:Regulatory functions:DNA interactions:Cellular processes:Sporulation and germination:Unknown function:Enzymes of unknown specificity:Information storage and processing:Cellular processes and signaling:Metabolism:Poorly characterized" 282 "Diaminopimelate decarboxylase:Ornithine carbamoyltransferase:Isopropylmalate/homocitrate/citramalate synthases:Argininosuccinate synthase:Argininosuccinate lyase:Acetolactate synthase, small (regulatory) subunit:Acetylglutamate kinase:ABC-type amino acid transport system, permease component:ABC-type amino acid transport/signal transduction systems, periplasmic component/domain:ABC-type polar amino acid transport system, ATPase component:N-acetylglutamate synthase and related acetyltransferases:N-acetylglutamate synthase (N-acetylornithine aminotransferase):Pyrrolidone-carboxylate peptidase (N-terminal pyroglutamyl peptidase):K+-transporting ATPase, A chain:K+-transporting ATPase, c chain:High-affinity K+ transport system, ATPase chain B:Predicted membrane protein:Ornithine/acetylornithine aminotransferase:Amino acid transport and metabolism:Posttranslational modification, protein turnover, chaperones:Inorganic ion transport and metabolism:Alanine aspartate and glutamate metabolism:Valine leucine and isoleucine biosynthesis:Lysine biosynthesis:Arginine and proline metabolism:Pyruvate metabolism:Butanoate metabolism:C5-Branched dibasic acid metabolism:Pantothenate and CoA biosynthesis:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:Two-component system:Function unknown:Signal transduction mechanisms:argG:acolac_sm:ArgJ:pyro_pdase:orni_carb_tr:kdpA:kdpC:argD:argB:argH:leuA_bact:lysA:ATPase_P-type:HEQRo_perm_3TM:Pyruvate family:Carbohydrate Metabolism:Amino Acid Metabolism:Metabolism of Cofactors and Vitamins:Environmental Information Processing:Signal Transduction:Global:Metabolism:Protein fate:Degradation of proteins, peptides, and glycopeptides:Transport and binding proteins:Amino acids, peptides and amines:Cations and iron carrying compounds:Amino acid biosynthesis:Aspartate family:Glutamate family:Metabolism:Cellular processes and signaling:Metabolism:Poorly characterized" 283 "Adenylosuccinate lyase:Phosphoribosylaminoimidazole carboxylase (NCAIR synthetase):Phosphoribosylcarboxyaminoimidazole (NCAIR) mutase:Glycosidases:Uroporphyrinogen-III decarboxylase:Adenine/guanine phosphoribosyltransferases and related PRPP-binding proteins:Signal transduction histidine kinase:Glycine/D-amino acid oxidases (deaminating):Spermidine/putrescine-binding periplasmic protein:Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain:Cell division protein FtsI/penicillin-binding protein 2:UDP-N-acetylmuramyl pentapeptide synthase:UDP-N-acetylmuramoylalanine-D-glutamate ligase:Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific:Uncharacterized ABC-type transport system, periplasmic component/surface lipoprotein:Transcriptional regulators:Xanthine/uracil permeases:Permeases:ABC-type uncharacterized transport systems, ATPase components:Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein):Cystathionine beta-lyase family protein involved in aluminum resistance:Amino acid transport and metabolism:Nucleotide transport and metabolism:Carbohydrate transport and metabolism:Coenzyme transport and metabolism:Transcription:Cell wall/membrane/envelope biogenesis:Inorganic ion transport and metabolism:Purine metabolism:Alanine aspartate and glutamate metabolism:Lysine biosynthesis:Phenylalanine metabolism:D-Glutamine and D-glutamate metabolism:D-Alanine metabolism:Starch and sucrose metabolism:Peptidoglycan biosynthesis:Porphyrin and chlorophyll metabolism:Nitrogen metabolism:Metabolic pathways:Biosynthesis of secondary metabolites:ABC transporters:Phosphotransferase system (PTS):General function prediction only:Signal transduction mechanisms:ncs2:EIIB_glc:purB:murD:murF:purK:purE:hemE:dltC:XPRTase:trehalose_treC:LTA_DltD:Metabolism:Global:Metabolism:Membrane Transport:Environmental Information Processing:Metabolism of Cofactors and Vitamins:Glycan Biosynthesis and Metabolism:Metabolism of Other Amino Acids:Amino Acid Metabolism:Nucleotide Metabolism:Energy Metabolism:Transport and binding proteins:Carbohydrate Metabolism:Nucleosides, purines and pyrimidines:Biosynthesis of cofactors, prosthetic groups, and carriers:Heme, porphyrin, and cobalamin:Signal transduction:PTS:Cell envelope:Biosynthesis and degradation of murein sacculus and peptidoglycan:Information storage and processing:Cellular processes and signaling:Metabolism:Poorly characterized:Salvage of nucleosides and nucleotides:Purine ribonucleotide biosynthesis:Purines, pyrimidines, nucleosides, and nucleotides" 284 "Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase:Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase:Short-chain dehydrogenases of various substrate specificities:Zn-dependent protease with chaperone function:Proline dehydrogenase:Predicted dehydrogenase:Amino acid transporters:ADP-ribose pyrophosphatase:Predicted transcriptional regulators:Fructose-1,6-bisphosphatase/sedoheptulose 1,7-bisphosphatase and related proteins:Predicted Rossmann fold nucleotide-binding protein:Uncharacterized proteins, homologs of microcin C7 resistance protein MccF:Acetyltransferases, including N-acetylases of ribosomal proteins:Beta-lactamase class C and other penicillin binding proteins:Transcriptional regulators:Putative homoserine kinase type II (protein kinase fold):Predicted ring-cleavage extradiol dioxygenase:Predicted glycosyl hydrolase:Uncharacterized protein conserved in bacteria:Amino acid transport and metabolism:Nucleotide transport and metabolism:Carbohydrate transport and metabolism:Coenzyme transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:Posttranslational modification, protein turnover, chaperones:Glycolysis / Gluconeogenesis:Pentose phosphate pathway:Fructose and mannose metabolism:Fatty acid biosynthesis:Lysine degradation:Arginine and proline metabolism:Histidine metabolism:Tyrosine metabolism:Phenylalanine metabolism:Benzoate degradation:Phenylalanine tyrosine and tryptophan biosynthesis:Novobiocin biosynthesis:D-Arginine and D-ornithine metabolism:D-Alanine metabolism:Pyruvate metabolism:Naphthalene degradation:Aminobenzoate degradation:Ethylbenzene degradation:Limonene and pinene degradation:Biosynthesis of unsaturated fatty acids:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:General function prediction only:Function unknown:glpX:TIGR00730:D_amino_aminoT:hisC:mal_quin_oxido:Defense mechanisms:Metabolism:Carbohydrate Metabolism:Lipid Metabolism:Amino Acid Metabolism:Metabolism of Other Amino Acids:Metabolism of Terpenoids and Polyketides:Biosynthesis of Other Secondary Metabolites:Xenobiotics Biodegradation and Metabolism:Global:Metabolism:Energy metabolism:Amino acids and amines:Pentose phosphate pathway:TCA cycle:Hypothetical proteins:Conserved:Amino acid biosynthesis:Histidine family:Information storage and processing:Cellular processes and signaling:Metabolism:Poorly characterized" 285 "Dimethyladenosine transferase (rRNA methylation):Integral membrane protein possibly involved in chromosome condensation:2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase:Membrane carboxypeptidase (penicillin-binding protein):Zn-dependent proteases:Cyclopropane fatty acid synthase and related methyltransferases:Sugar phosphate permease:Methylase of polypeptide chain release factors:Uncharacterized protein conserved in bacteria:Membrane protein involved in cytochrome C biogenesis:Cell cycle control, cell division, chromosome partitioning:Carbohydrate transport and metabolism:Lipid transport and metabolism:Translation, ribosomal structure and biogenesis:Cell wall/membrane/envelope biogenesis:Posttranslational modification, protein turnover, chaperones:Terpenoid backbone biosynthesis:Metabolic pathways:Biosynthesis of secondary metabolites:General function prediction only:Function unknown:ispF:crcB:hemK_fam:efflux_EmrB:ksgA:PBP_1a_fam:Metabolism:Poorly characterized:Biosynthesis and degradation of murein sacculus and peptidoglycan:Cell envelope:Other:Biosynthesis of cofactors, prosthetic groups, and carriers:General:Unknown function:Other:Transport and binding proteins:Protein modification and repair:Protein fate:tRNA and rRNA base modification:Protein synthesis:Metabolism:Metabolism:Global:Information storage and processing:Metabolism of Terpenoids and Polyketides:Cellular processes and signaling" 286 "Energy production and conversion:Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase:Translation elongation factors (GTPases):Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain:Nitroreductase:ABC-type multidrug transport system, ATPase component:Oligoendopeptidase F:Transcriptional regulators:Homoserine acetyltransferase:Formate/nitrite family of transporters:3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase:Putative regulator of cell autolysis:Uncharacterized protein conserved in bacteria:Site-specific recombinase XerD:Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain:Amino acid transport and metabolism:Coenzyme transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:Replication, recombination and repair:Inorganic ion transport and metabolism:Cysteine and methionine metabolism:Lysine degradation:Arginine and proline metabolism:Phenylalanine metabolism:Phenylalanine tyrosine and tryptophan biosynthesis:D-Arginine and D-ornithine metabolism:D-Alanine metabolism:Sulfur metabolism:Metabolic pathways:Biosynthesis of secondary metabolites:ABC transporters:Two-component system:Function unknown:Signal transduction mechanisms:pepF:sensory_box:small_GTP:D_amino_aminoT:DAHP_synth_Bsub:Defense mechanisms:Degradation of proteins, peptides, and glycopeptides:Protein fate:Small molecule interactions:Regulatory functions:Amino acids and amines:Energy metabolism:Metabolism:Global:Metabolism:Signal Transduction:Membrane Transport:Environmental Information Processing:Metabolism of Other Amino Acids:Amino Acid Metabolism:General:Energy Metabolism:Amino acid biosynthesis:Aromatic amino acid family:Information storage and processing:Cellular processes and signaling:Metabolism:Poorly characterized:Unknown function" 287 "Energy production and conversion:Pyrroline-5-carboxylate reductase:Lactoylglutathione lyase and related lyases:Uncharacterized NAD(FAD)-dependent dehydrogenases:NADPH:quinone reductase and related Zn-dependent oxidoreductases:Aldo/keto reductases, related to diketogulonate reductase:NAD-dependent aldehyde dehydrogenases:Predicted 6-phosphogluconate dehydrogenase:ABC-type transport system involved in multi-copper enzyme maturation, permease component:Nicotinic acid phosphoribosyltransferase:NADH:flavin oxidoreductases, Old Yellow Enzyme family:Mn2+ and Fe2+ transporters of the NRAMP family:Uncharacterized oxidoreductases, Fe-dependent alcohol dehydrogenase family:Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases:Lysophospholipase L1 and related esterases:Predicted dithiol-disulfide isomerase involved in polyketide biosynthesis:Arabinose efflux permease:DNA alkylation repair enzyme:Amino acid transport and metabolism:Carbohydrate transport and metabolism:Coenzyme transport and metabolism:Replication, recombination and repair:Inorganic ion transport and metabolism:Glycolysis / Gluconeogenesis:Pentose phosphate pathway:Pentose and glucuronate interconversions:Fructose and mannose metabolism:Ascorbate and aldarate metabolism:Fatty acid metabolism:Oxidative phosphorylation:Valine leucine and isoleucine degradation:Lysine degradation:Arginine and proline metabolism:Histidine metabolism:Bisphenol degradation:Tryptophan metabolism:beta-Alanine metabolism:Glutathione metabolism:Glycerolipid metabolism:Pyruvate metabolism:Chloroalkane and chloroalkene degradation:Propanoate metabolism:Butanoate metabolism:Nicotinate and nicotinamide metabolism:Limonene and pinene degradation:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:ABC transporters:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:proC:gnd_rel:nramp:NAPRTase_put:oxido_grp_1:Glutamate family:Carbohydrate Metabolism:Energy Metabolism:Lipid Metabolism:Amino Acid Metabolism:Metabolism of Other Amino Acids:Metabolism of Cofactors and Vitamins:Metabolism of Terpenoids and Polyketides:Xenobiotics Biodegradation and Metabolism:Environmental Information Processing:Membrane Transport:Global:Metabolism:Energy metabolism:Pentose phosphate pathway:Transport and binding proteins:Cations and iron carrying compounds:Unknown function:Enzymes of unknown specificity:Amino acid biosynthesis:Metabolism:Biosynthesis of cofactors, prosthetic groups, and carriers:Pyridine nucleotides:Information storage and processing:Metabolism:Poorly characterized" 288 "Trk-type K+ transport systems, membrane components:Nucleoside-diphosphate-sugar epimerases:Predicted Zn-dependent peptidases:Bacterial nucleoid DNA-binding protein:Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases):ABC-type dipeptide/oligopeptide/nickel transport systems, permease components:Transcriptional regulator:D-alanyl-D-alanine carboxypeptidase:Uncharacterized protein conserved in bacteria:Predicted ring-cleavage extradiol dioxygenase:3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase:Uncharacterized protein conserved in bacteria:Uncharacterized protein conserved in bacteria:Amino acid transport and metabolism:Carbohydrate transport and metabolism:Lipid transport and metabolism:Transcription:Replication, recombination and repair:Cell wall/membrane/envelope biogenesis:Inorganic ion transport and metabolism:Fatty acid biosynthesis:Phenylalanine tyrosine and tryptophan biosynthesis:Peptidoglycan biosynthesis:Biosynthesis of unsaturated fatty acids:Metabolic pathways:Biosynthesis of secondary metabolites:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:Function unknown:DAHP_synth_Bsub:spo_yunB:thiol_BshC:Poorly characterized:Lipid Metabolism:Amino Acid Metabolism:Glycan Biosynthesis and Metabolism:Global:Metabolism:Cellular processes:Sporulation and germination:Amino acid biosynthesis:Aromatic amino acid family:Biosynthesis of cofactors, prosthetic groups, and carriers:Glutathione and analogs:Information storage and processing:Cellular processes and signaling:Metabolism:Metabolism" 289 "Energy production and conversion:Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit:Ferredoxin:Permeases of the drug/metabolite transporter (DMT) superfamily:ABC-type amino acid transport system, permease component:ABC-type amino acid transport/signal transduction systems, periplasmic component/domain:Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit:dTDP-D-glucose 4,6-dehydratase:Predicted membrane protein:Chitinase:Amino acid transport and metabolism:Carbohydrate transport and metabolism:Cell wall/membrane/envelope biogenesis:Glycolysis / Gluconeogenesis:Citrate cycle (TCA cycle):Valine leucine and isoleucine biosynthesis:Amino sugar and nucleotide sugar metabolism:Pyruvate metabolism:Butanoate metabolism:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:General function prediction only:Function unknown:Signal transduction mechanisms:2A0309:HEQRo_perm_3TM:CDP_4_6_dhtase:Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides:Carbohydrate Metabolism:Amino Acid Metabolism:Global:Metabolism:Transport and binding proteins:Amino acids, peptides and amines:Cell envelope:Metabolism:Cellular processes and signaling:Metabolism:Poorly characterized" 290 "Energy production and conversion:Adenylosuccinate synthase:L-asparaginase/archaeal Glu-tRNAGln amidotransferase subunit D:Acetate kinase:IMP dehydrogenase/GMP reductase:Sugar kinases, ribokinase family:Predicted sugar phosphatases of the HAD superfamily:Sulfate permease and related transporters (MFS superfamily):cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases:Membrane-associated phospholipid phosphatase:Predicted permeases:Cytochrome c biogenesis protein:Protoporphyrinogen oxidase:Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific:Uncharacterized protein SCO1/SenC/PrrC, involved in biogenesis of respiratory and photosynthetic systems:Permeases:Sugar phosphate permease:Predicted membrane protein:Anaerobic C4-dicarboxylate transporter:Transcriptional antiterminator:Sporulation control protein:Nitric oxide synthase, oxygenase domain:Amino acid transport and metabolism:Nucleotide transport and metabolism:Carbohydrate transport and metabolism:Coenzyme transport and metabolism:Lipid transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:Posttranslational modification, protein turnover, chaperones:Inorganic ion transport and metabolism:Fructose and mannose metabolism:Purine metabolism:Alanine aspartate and glutamate metabolism:Arginine and proline metabolism:Taurine and hypotaurine metabolism:Cyanoamino acid metabolism:Starch and sucrose metabolism:Amino sugar and nucleotide sugar metabolism:Glycerophospholipid metabolism:Pyruvate metabolism:Aminobenzoate degradation:Propanoate metabolism:Methane metabolism:Carbon fixation pathways in prokaryotes:Porphyrin and chlorophyll metabolism:Nitrogen metabolism:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:Phosphotransferase system (PTS):General function prediction only:Function unknown:Signal transduction mechanisms:ackA:purA:proto_IX_ox:Dcu:EIIB_glc:2A0104:GMP_reduct_2:HAD-SF-IIA-hyp2:Poorly characterized:Carbohydrate Metabolism:Energy Metabolism:Lipid Metabolism:Nucleotide Metabolism:Amino Acid Metabolism:Metabolism of Other Amino Acids:Metabolism of Cofactors and Vitamins:Xenobiotics Biodegradation and Metabolism:Environmental Information Processing:Membrane Transport:Global:Metabolism:Energy metabolism:Fermentation:Purines, pyrimidines, nucleosides, and nucleotides:Nucleotide and nucleoside interconversions:Purine ribonucleotide biosynthesis:Transport and binding proteins:Carbohydrates, organic alcohols, and acids:Unknown function:Enzymes of unknown specificity:Biosynthesis of cofactors, prosthetic groups, and carriers:Heme, porphyrin, and cobalamin:Signal transduction:PTS:Information storage and processing:Cellular processes and signaling:Metabolism:Metabolism" 291 "Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily):Putative intracellular protease/amidase:Myo-inositol-1-phosphate synthase:Lipid transport and metabolism:Streptomycin biosynthesis:Inositol phosphate metabolism:Metabolic pathways:Biosynthesis of secondary metabolites:General function prediction only:LPXTG_anchor:Cell envelope:Other:Metabolism:Poorly characterized:Metabolism:Metabolism:Global:Biosynthesis of Other Secondary Metabolites:Carbohydrate Metabolism" 292 "Methionine aminopeptidase:Ribosomal protein S10:Ribosomal protein L3:Ribosomal protein L4:Ribosomal protein L23:Ribosomal protein L2:Ribosomal protein S13:Ribosomal protein S11:Ribosomal protein S19:DNA-directed RNA polymerase, alpha subunit/40 kD subunit:Translation initiation factor 1 (IF-1):Translation elongation factors (GTPases):Adenylate kinase and related kinases:Ribosomal protein HS6-type (S12/L30/L7a):Nucleotide transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:Purine metabolism:Pyrimidine metabolism:Metabolic pathways:Biosynthesis of secondary metabolites:Ribosome:RNA polymerase:infA:small_GTP:met_pdase_I:rpmJ_bact:rpsJ_bact:rpsS_bact:rplB_bact:adk:rpoA:L3_bact:bact_S13:bact_S11:rplD_bact:Unknown function:Nucleotide Metabolism:Genetic Information Processing:Transcription:Translation:Global:Metabolism:Purines, pyrimidines, nucleosides, and nucleotides:Nucleotide and nucleoside interconversions:Transcription:DNA-dependent RNA polymerase:Protein synthesis:Ribosomal proteins: synthesis and modification:Translation factors:Protein fate:Protein modification and repair:Metabolism:General:Information storage and processing:Metabolism" 293 "Acetyltransferase (isoleucine patch superfamily):FOG: CBS domain:UDP-glucose 4-epimerase:Phosphotransferase system cellobiose-specific component IIA:Nitrate/nitrite transporter:Protein related to penicillin acylase:Beta-lactamase class A:Endoglucanase Y:Uncharacterized conserved protein:Carbohydrate transport and metabolism:Cell wall/membrane/envelope biogenesis:Inorganic ion transport and metabolism:Penicillin and cephalosporin biosynthesis:Biosynthesis of secondary metabolites:Two-component system:Phosphotransferase system (PTS):General function prediction only:Function unknown:efflux_EmrB:LPXTG_anchor:cognate_SipW:Defense mechanisms:Cellular processes and signaling:Biosynthesis of Other Secondary Metabolites:Environmental Information Processing:Membrane Transport:Signal Transduction:Global:Metabolism:Transport and binding proteins:Other:Cell envelope:Other:Metabolism:Metabolism:Poorly characterized" 294 "Energy production and conversion:FAD/FMN-containing dehydrogenases:Glycosidases:Acetyl-CoA hydrolase:Glycosyltransferases involved in cell wall biogenesis:Amino acid transporters:Carbamate kinase:Superoxide dismutase:Glycine/D-amino acid oxidases (deaminating):Predicted xylanase/chitin deacetylase:1-deoxy-D-xylulose 5-phosphate reductoisomerase:Amino acid transporters:NAD-dependent protein deacetylases, SIR2 family:NAD-dependent aldehyde dehydrogenases:Cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes:Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs:Predicted membrane protein, hemolysin III homolog:Predicted transcriptional regulators:Alcohol dehydrogenase, class IV:Sugar phosphate permease:Uncharacterized conserved protein:Uncharacterized protein conserved in bacteria:ABC-type maltose transport systems, permease component:ABC-type sugar transport systems, ATPase components:Amino acid transport and metabolism:Carbohydrate transport and metabolism:Lipid transport and metabolism:Transcription:Cell wall/membrane/envelope biogenesis:Inorganic ion transport and metabolism:Glycolysis / Gluconeogenesis:Pentose and glucuronate interconversions:Galactose metabolism:Ascorbate and aldarate metabolism:Fatty acid metabolism:Purine metabolism:Valine leucine and isoleucine degradation:Geraniol degradation:Lysine degradation:Arginine and proline metabolism:Histidine metabolism:Tryptophan metabolism:beta-Alanine metabolism:Starch and sucrose metabolism:Glycerolipid metabolism:Pyruvate metabolism:Chloroalkane and chloroalkene degradation:Naphthalene degradation:Propanoate metabolism:Thiamine metabolism:Terpenoid backbone biosynthesis:Limonene and pinene degradation:Nitrogen metabolism:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:ABC transporters:Sulfur relay system:General function prediction only:Function unknown:Dxr:arcC:2A0302:hlyIII:spore_pdaA:YgfH_subfam:Information storage and processing:Carbohydrate Metabolism:Energy Metabolism:Lipid Metabolism:Nucleotide Metabolism:Amino Acid Metabolism:Metabolism of Other Amino Acids:Metabolism of Cofactors and Vitamins:Metabolism of Terpenoids and Polyketides:Xenobiotics Biodegradation and Metabolism:Genetic Information Processing:Folding Sorting and Degradation:Environmental Information Processing:Membrane Transport:Global:Metabolism:Energy metabolism:Amino acids and amines:Transport and binding proteins:Amino acids, peptides and amines:Cellular processes:Sporulation and germination:Biosynthesis of cofactors, prosthetic groups, and carriers:Other:Metabolism:Cellular processes and signaling:Metabolism:Poorly characterized" 295 "" 296 "Transketolase:Methionyl-tRNA synthetase:Multimeric flavodoxin WrbA:ABC-type molybdate transport system, periplasmic component:Predicted transcriptional regulators:Arsenite efflux pump ACR3 and related permeases:Cold shock proteins:Uncharacterized conserved protein:Acetyltransferases, including N-acetylases of ribosomal proteins:Galactose mutarotase and related enzymes:Negative regulator of septation ring formation:Uncharacterized protein conserved in bacteria:Cell cycle control, cell division, chromosome partitioning:Carbohydrate transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:Inorganic ion transport and metabolism:Pentose phosphate pathway:Tyrosine metabolism:Benzoate degradation:Selenocompound metabolism:Naphthalene degradation:Aminobenzoate degradation:Ethylbenzene degradation:Limonene and pinene degradation:Aminoacyl-tRNA biosynthesis:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:ABC transporters:General function prediction only:Function unknown:tktlase_bact:metG:modA:Cellular processes and signaling:Carbohydrate Metabolism:Amino Acid Metabolism:Metabolism of Other Amino Acids:Metabolism of Terpenoids and Polyketides:Xenobiotics Biodegradation and Metabolism:Genetic Information Processing:Translation:Environmental Information Processing:Membrane Transport:Global:Metabolism:Energy metabolism:Pentose phosphate pathway:Protein synthesis:tRNA aminoacylation:Transport and binding proteins:Anions:Information storage and processing:Metabolism:Metabolism:Poorly characterized" 297 "Aspartyl/asparaginyl-tRNA synthetases:Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase]:Ketol-acid reductoisomerase:Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase:Chorismate synthase:Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase:Dihydroxyacid dehydratase/phosphogluconate dehydratase:Tryptophan synthase beta chain:Indole-3-glycerol phosphate synthase:Phosphoribosylanthranilate isomerase:Tryptophan synthase alpha chain:Tyrosyl-tRNA synthetase:Prephenate dehydrogenase:Threonyl-tRNA synthetase:Prolyl-tRNA synthetase:Homoserine dehydrogenase:Anthranilate/para-aminobenzoate synthases component II:Anthranilate phosphoribosyltransferase:Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily):Na+-dependent transporters of the SNF family:Threonine dehydratase:Lysyl-tRNA synthetase (class I):Amino acid transport and metabolism:Carbohydrate transport and metabolism:Coenzyme transport and metabolism:Translation, ribosomal structure and biogenesis:Glycine serine and threonine metabolism:Cysteine and methionine metabolism:Valine leucine and isoleucine degradation:Valine leucine and isoleucine biosynthesis:Lysine biosynthesis:Arginine and proline metabolism:Histidine metabolism:Tyrosine metabolism:Phenylalanine metabolism:Phenylalanine tyrosine and tryptophan biosynthesis:Novobiocin biosynthesis:Butanoate metabolism:C5-Branched dibasic acid metabolism:Pantothenate and CoA biosynthesis:Aminoacyl-tRNA biosynthesis:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:General function prediction only:aroC:ilvD:acolac_lg:tyrS:trpA:trpB:proS_fam_I:thrS:aspS_arch:ilvC:lysS_arch:trpG_papA:ilvE_I:hisC:trpD:THD1:Translation:Genetic Information Processing:Metabolism:Biosynthesis of Other Secondary Metabolites:Metabolism of Cofactors and Vitamins:Amino Acid Metabolism:Metabolism:Carbohydrate Metabolism:Poorly characterized:Information storage and processing:Histidine family:Pyruvate family:Aromatic amino acid family:Amino acid biosynthesis:tRNA aminoacylation:Protein synthesis:Metabolism:Global" 298 "Cell division GTPase:Pyridoxine biosynthesis enzyme:Predicted glutamine amidotransferase involved in pyridoxine biosynthesis:Putative effector of murein hydrolase:Putative effector of murein hydrolase LrgA:Transcriptional regulators:Arabinose efflux permease:Predicted metal-dependent enzyme:Cell cycle control, cell division, chromosome partitioning:Carbohydrate transport and metabolism:Coenzyme transport and metabolism:Transcription:Cell wall/membrane/envelope biogenesis:Vitamin B6 metabolism:General function prediction only:ftsZ:TIGR00343:PLP_synth_Pdx2:Biosynthesis of cofactors, prosthetic groups, and carriers:Cell division:Cellular processes:Metabolism:Metabolism of Cofactors and Vitamins:Poorly characterized:Metabolism:Cellular processes and signaling:Information storage and processing:Pyridoxine" 299 "Putative translation initiation inhibitor, yjgF family:Glycosidases:Acetyltransferases:Mannose-6-phosphate isomerase:Bacterial nucleoid DNA-binding protein:Amidases related to nicotinamidase:DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog:Beta-lactamase class C and other penicillin binding proteins:Cytochrome P450:Zn-dependent carboxypeptidase:Uncharacterized conserved protein:Putative homoserine kinase type II (protein kinase fold):Uncharacterized conserved protein:Uncharacterized integral membrane protein:Pyruvate decarboxylase and related thiamine pyrophosphate-requiring enzymes:Amino acid transport and metabolism:Carbohydrate transport and metabolism:Coenzyme transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:Replication, recombination and repair:Bisphenol degradation:Tryptophan metabolism:Polycyclic aromatic hydrocarbon degradation:Aminobenzoate degradation:Limonene and pinene degradation:Biosynthesis of siderophore group nonribosomal peptides:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:RNA polymerase:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:Function unknown:staph_tand_hypo:sigma70-ECF:Defense mechanisms:Metabolism:Transcription:Genetic Information Processing:Metabolism:Poorly characterized:Xenobiotics Biodegradation and Metabolism:Metabolism:Cellular processes and signaling:Metabolism of Terpenoids and Polyketides:Information storage and processing:Global:Amino Acid Metabolism" 300 "Cell division GTPase:Thymidylate synthase:Ribosome recycling factor:Aspartate/tyrosine/aromatic aminotransferase:Glycosyltransferases involved in cell wall biogenesis:Signal transduction histidine kinase:Predicted metal-dependent membrane protease:Uncharacterized conserved protein:Uncharacterized protein conserved in bacteria:Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily:Disulfide bond formation protein DsbB:Transcriptional regulators:Uncharacterized conserved protein:Predicted membrane protein:Uncharacterized protein conserved in bacteria:Cell cycle control, cell division, chromosome partitioning:Amino acid transport and metabolism:Nucleotide transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:Cell wall/membrane/envelope biogenesis:Posttranslational modification, protein turnover, chaperones:Pyrimidine metabolism:Alanine aspartate and glutamate metabolism:Cysteine and methionine metabolism:Arginine and proline metabolism:Tyrosine metabolism:Phenylalanine metabolism:Phenylalanine tyrosine and tryptophan biosynthesis:Novobiocin biosynthesis:One carbon pool by folate:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:General function prediction only:Function unknown:Signal transduction mechanisms:ftsZ:TIGR00374:frr:DegV:ccpA:integ_TIGR01906:thym_sym:DNA interactions:Regulatory functions:2'-Deoxyribonucleotide metabolism:Purines, pyrimidines, nucleosides, and nucleotides:Metabolism:Metabolism:Global:Biosynthesis of Other Secondary Metabolites:Metabolism of Cofactors and Vitamins:Amino Acid Metabolism:Cellular processes:Nucleotide Metabolism:Cell division:Hypothetical proteins:Conserved:Unknown function:General:Information storage and processing:Cellular processes and signaling:Metabolism:Poorly characterized:Translation factors:Protein synthesis" 301 "Energy production and conversion:Histidyl-tRNA synthetase:Imidazoleglycerol-phosphate dehydratase:Amino acid transporters:Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases):ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component:Histidinol phosphatase and related hydrolases of the PHP family:Transcriptional regulators:L-lactate permease:Aspartate racemase:D-serine dehydratase:Uncharacterized conserved protein:ATP phosphoribosyltransferase involved in histidine biosynthesis:Amino acid transport and metabolism:Lipid transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:Cell wall/membrane/envelope biogenesis:Inorganic ion transport and metabolism:Fatty acid biosynthesis:Alanine aspartate and glutamate metabolism:Glycine serine and threonine metabolism:Histidine metabolism:Aminoacyl-tRNA biosynthesis:Biosynthesis of unsaturated fatty acids:Metabolic pathways:Biosynthesis of secondary metabolites:ABC transporters:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:Function unknown:asp_race:hisS:hisZ_biosyn_reg:hisJ_fam:D_Ser_am_lyase:beta_rpt_yvtn:Cellular processes and signaling:Information storage and processing:Histidine family:Amino acid biosynthesis:tRNA aminoacylation:Protein synthesis:Amino acids and amines:Energy metabolism:Metabolism:Metabolism:Global:Membrane Transport:Environmental Information Processing:Translation:Genetic Information Processing:Amino Acid Metabolism:Poorly characterized:Lipid Metabolism:Metabolism" 302 "Energy production and conversion:Succinyl-CoA synthetase, beta subunit:Succinyl-CoA synthetase, alpha subunit:Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase:Predicted GTPase:Dephospho-CoA kinase:Carbonic anhydrase:Methylated DNA-protein cysteine methyltransferase:ATPases involved in chromosome partitioning:Zn-dependent hydrolases, including glyoxylases:Aldo/keto reductases, related to diketogulonate reductase:Glutamate racemase:ABC-type multidrug transport system, permease component:NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit:Lactate dehydrogenase and related dehydrogenases:Oligoendopeptidase F:Transcriptional regulators:Uncharacterized conserved protein:Uncharacterized protein conserved in bacteria:Cell cycle control, cell division, chromosome partitioning:Amino acid transport and metabolism:Coenzyme transport and metabolism:Transcription:Replication, recombination and repair:Cell wall/membrane/envelope biogenesis:Inorganic ion transport and metabolism:Citrate cycle (TCA cycle):Pentose phosphate pathway:Oxidative phosphorylation:Histidine metabolism:Tyrosine metabolism:Phenylalanine metabolism:Phenylalanine tyrosine and tryptophan biosynthesis:Novobiocin biosynthesis:D-Glutamine and D-glutamate metabolism:Propanoate metabolism:C5-Branched dibasic acid metabolism:Carbon fixation pathways in prokaryotes:Pantothenate and CoA biosynthesis:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:General function prediction only:Function unknown:glut_race:TIGR00152:pepF:ogt:sucCoAbeta:sucCoAalpha:hisC:GTPase_YsxC:Defense mechanisms:Poorly characterized:Carbohydrate Metabolism:Energy Metabolism:Amino Acid Metabolism:Metabolism of Other Amino Acids:Metabolism of Cofactors and Vitamins:Biosynthesis of Other Secondary Metabolites:Global:Metabolism:Energy metabolism:TCA cycle:DNA metabolism:DNA replication, recombination, and repair:Protein synthesis:Other:Protein fate:Degradation of proteins, peptides, and glycopeptides:Amino acid biosynthesis:Histidine family:Biosynthesis of cofactors, prosthetic groups, and carriers:Pantothenate and coenzyme A:Cell envelope:Biosynthesis and degradation of murein sacculus and peptidoglycan:Information storage and processing:Cellular processes and signaling:Metabolism:Metabolism" 303 "Glycosidases:Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily):Phosphatidylglycerophosphatase A and related proteins:Predicted membrane protein:Uncharacterized proteins, homologs of lactam utilization protein B:Pterin-4a-carbinolamine dehydratase:Uncharacterized protein conserved in bacteria:Uncharacterized protein conserved in bacteria:Carbohydrate transport and metabolism:Coenzyme transport and metabolism:Lipid transport and metabolism:Starch and sucrose metabolism:Metabolic pathways:General function prediction only:Function unknown:yihY_not_rbn:spore_yutH:Poorly characterized:Carbohydrate Metabolism:Global:Metabolism:Cellular processes:Sporulation and germination:Unknown function:General:Metabolism:Metabolism" 304 "Energy production and conversion:Mg2+ and Co2+ transporters:Uncharacterized conserved protein:Transcriptional regulator:Uncharacterized protein required for formate dehydrogenase activity:Uncharacterized conserved protein:Transcriptional regulators:Predicted membrane protein:Predicted membrane protein:Transcriptional antiterminator:Transcription:Inorganic ion transport and metabolism:Function unknown:fdhD_narQ:Poorly characterized:Metabolism:Information storage and processing:Electron transport:Energy metabolism" 305 "Energy production and conversion:Lactoylglutathione lyase and related lyases:Protein-tyrosine-phosphatase:Rhodanese-related sulfurtransferase:Nitroreductase:Arsenite efflux pump ACR3 and related permeases:Acyl carrier protein phosphodiesterase:Uncharacterized conserved protein:Transcriptional regulators:Predicted transcriptional regulators:Predicted redox protein, regulator of disulfide bond formation:Transcriptional regulators:Cation transport ATPase:Putative NADPH-quinone reductase (modulator of drug activity B):Predicted membrane protein:Copper chaperone:Uncharacterized conserved protein:Predicted ester cyclase:Amino acid transport and metabolism:Lipid transport and metabolism:Transcription:Posttranslational modification, protein turnover, chaperones:Inorganic ion transport and metabolism:General function prediction only:Function unknown:Signal transduction mechanisms:TIGR00003:acr3:arsC_pI258_fam:organ_hyd_perox:Information storage and processing:Detoxification:Cellular processes:Cations and iron carrying compounds:Anions:Transport and binding proteins:Metabolism:Poorly characterized:Cellular processes and signaling" 306 "Energy production and conversion:Predicted GTPase:Thiol-disulfide isomerase and thioredoxins:Predicted hydrolases of the HAD superfamily:Aldo/keto reductases, related to diketogulonate reductase:Predicted dehydrogenases and related proteins:ABC-type multidrug transport system, ATPase and permease components:Type II secretory pathway, prepilin signal peptidase PulO and related peptidases:Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases:Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog):ABC-type enterochelin transport system, ATPase component:ABC-type enterochelin transport system, permease component:ABC-type enterochelin transport system, permease component:ABC-type enterochelin transport system, periplasmic component:Predicted integral membrane protein:Cell motility:Posttranslational modification, protein turnover, chaperones:Inorganic ion transport and metabolism:Bisphenol degradation:Polycyclic aromatic hydrocarbon degradation:Aminobenzoate degradation:Limonene and pinene degradation:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:ABC transporters:General function prediction only:Function unknown:Signal transduction mechanisms:Cof-subfamily:intg_mem_TP0381:lucif_BA3436:GTPase_YsxC:Intracellular trafficking, secretion, and vesicular transport:Defense mechanisms:Xenobiotics Biodegradation and Metabolism:Cellular processes and signaling:Metabolism of Terpenoids and Polyketides:Metabolism:Poorly characterized:Enzymes of unknown specificity:Unknown function:Other:Protein synthesis:Metabolism:Metabolism:Global:Membrane Transport:Environmental Information Processing" 307 "Predicted translation initiation factor 2B subunit, eIF-2B alpha/beta/delta family:Exopolyphosphatase:Zn-dependent hydrolases, including glyoxylases:Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain:Cell division protein FtsI/penicillin-binding protein 2:ADP-ribose pyrophosphatase:ABC-type antimicrobial peptide transport system, ATPase component:Predicted membrane protein:Nucleotide transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:Cell wall/membrane/envelope biogenesis:Inorganic ion transport and metabolism:Purine metabolism:Cysteine and methionine metabolism:Penicillin and cephalosporin biosynthesis:Metabolic pathways:Biosynthesis of secondary metabolites:Two-component system:General function prediction only:Function unknown:Signal transduction mechanisms:salvage_mtnA:spore_III_AF:Defense mechanisms:Metabolism:Cellular processes and signaling:Information storage and processing:Aspartate family:Amino acid biosynthesis:Sporulation and germination:Cellular processes:Metabolism:Metabolism:Global:Signal Transduction:Environmental Information Processing:Biosynthesis of Other Secondary Metabolites:Amino Acid Metabolism:Poorly characterized:Nucleotide Metabolism" 308 "Energy production and conversion:Acetyltransferase (isoleucine patch superfamily):tRNA delta(2)-isopentenylpyrophosphate transferase:Predicted choline kinase involved in LPS biosynthesis:Signal transduction histidine kinase:DNA polymerase III, epsilon subunit and related 3'-5' exonucleases:Transcriptional regulator:Ribonucleases G and E:Acetyltransferases, including N-acetylases of ribosomal proteins:Arginine/lysine/ornithine decarboxylases:Regulators of stationary/sporulation gene expression:3-methyladenine DNA glycosylase:Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain:Predicted transcriptional regulator:Predicted acetamidase/formamidase:Uncharacterized FAD-dependent dehydrogenases:Predicted transcriptional regulator with C-terminal CBS domains:Uncharacterized protein conserved in bacteria:Signal transduction histidine kinase:Uncharacterized protein conserved in bacteria:Uncharacterized protein conserved in bacteria:Uncharacterized conserved protein:Amino acid transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:Replication, recombination and repair:Cell wall/membrane/envelope biogenesis:Arginine and proline metabolism:Phenylalanine metabolism:Tryptophan metabolism:Cyanoamino acid metabolism:Aminobenzoate degradation:Styrene degradation:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:Base excision repair:General function prediction only:Function unknown:Signal transduction mechanisms:miaA:3mg:RNaseEG:lp_hng_hel_AbrB:DHAK_reg:DNA interactions:Regulatory functions:Metabolism:Metabolism:Global:Replication and Repair:Genetic Information Processing:Xenobiotics Biodegradation and Metabolism:Metabolism of Other Amino Acids:Poorly characterized:Amino Acid Metabolism:Metabolism:Cellular processes and signaling:Information storage and processing:tRNA and rRNA base modification:Protein synthesis:Degradation of RNA:Transcription:DNA replication, recombination, and repair:DNA metabolism" 309 "Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II:Predicted kinase:Transcriptional regulator:Predicted acyl esterases:ABC-type phosphate/phosphonate transport system, periplasmic component:Zinc metalloprotease (elastase):Amino acid transport and metabolism:Lipid transport and metabolism:Transcription:Inorganic ion transport and metabolism:ABC transporters:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:3A0109s03R:Membrane Transport:Poorly characterized:Environmental Information Processing:Information storage and processing:Anions:Transport and binding proteins:Metabolism" 310 "" 311 "Asp-tRNAAsn/Glu-tRNAGln amidotransferase B subunit (PET112 homolog):Protoheme ferro-lyase (ferrochelatase):Uroporphyrinogen-III decarboxylase:GMP synthase, PP-ATPase domain/subunit:Membrane carboxypeptidase (penicillin-binding protein):UDP-N-acetylmuramyl pentapeptide synthase:Protoporphyrinogen oxidase:Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific:Flagellar biosynthesis pathway, component FliP:Flagellar biosynthesis pathway, component FlhB:Flagellar biosynthesis pathway, component FliR:Flagellar motor switch protein:Flagellar motor switch/type III secretory pathway protein:Flagellar biosynthesis pathway, component FliQ:Nitrate/nitrite transporter:Uncharacterized protein conserved in bacteria:Nucleotide transport and metabolism:Carbohydrate transport and metabolism:Coenzyme transport and metabolism:Translation, ribosomal structure and biogenesis:Cell wall/membrane/envelope biogenesis:Cell motility:Inorganic ion transport and metabolism:Purine metabolism:Lysine biosynthesis:Amino sugar and nucleotide sugar metabolism:Peptidoglycan biosynthesis:Porphyrin and chlorophyll metabolism:Aminoacyl-tRNA biosynthesis:Metabolic pathways:Biosynthesis of secondary metabolites:Bacterial chemotaxis:Flagellar assembly:Phosphotransferase system (PTS):Function unknown:hemH:gatB:proto_IX_ox:EIIB_glc:guaA_Cterm:murF:hemE:PBP_1a_fam:fliN:Intracellular trafficking, secretion, and vesicular transport:Information storage and processing:Carbohydrate Metabolism:Nucleotide Metabolism:Amino Acid Metabolism:Glycan Biosynthesis and Metabolism:Metabolism of Cofactors and Vitamins:Genetic Information Processing:Translation:Environmental Information Processing:Membrane Transport:Cellular Processes:Cell Motility:Global:Metabolism:Purines, pyrimidines, nucleosides, and nucleotides:Purine ribonucleotide biosynthesis:Protein synthesis:tRNA aminoacylation:Cellular processes:Chemotaxis and motility:Biosynthesis of cofactors, prosthetic groups, and carriers:Heme, porphyrin, and cobalamin:Signal transduction:PTS:Cell envelope:Biosynthesis and degradation of murein sacculus and peptidoglycan:Metabolism:Cellular processes and signaling:Metabolism:Poorly characterized" 312 "Sulfate permease and related transporters (MFS superfamily):Signal peptidase I:Bacterial cell division membrane protein:ABC-type multidrug transport system, ATPase component:16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases:Xanthine/uracil permeases:Zn-dependent dipeptidase, microsomal dipeptidase homolog:Arabinose efflux permease:Na+/panthothenate symporter:Cell cycle control, cell division, chromosome partitioning:Amino acid transport and metabolism:Nucleotide transport and metabolism:Carbohydrate transport and metabolism:Coenzyme transport and metabolism:Translation, ribosomal structure and biogenesis:Inorganic ion transport and metabolism:ABC transporters:Protein export:TIGR00093:efflux_EmrB:sss:sigpep_I_bact:ftsW:Intracellular trafficking, secretion, and vesicular transport:Defense mechanisms:Information storage and processing:Cell division:Cellular processes:Other:Cations and iron carrying compounds:Transport and binding proteins:Protein and peptide secretion and trafficking:Protein fate:tRNA and rRNA base modification:Protein synthesis:Genetic Information Processing:Membrane Transport:Environmental Information Processing:Metabolism:Folding Sorting and Degradation:Cellular processes and signaling" 313 "Phosphoribosylamine-glycine ligase:Type I restriction-modification system methyltransferase subunit:Predicted dehydrogenases and related proteins:RNase PH:Restriction endonuclease S subunits:Enzyme related to GTP cyclohydrolase I:Amidases related to nicotinamidase:ABC-type polysaccharide/polyol phosphate export systems, permease component:Transcriptional regulators:Uncharacterized protein conserved in bacteria:Nucleotide transport and metabolism:Carbohydrate transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:Cell wall/membrane/envelope biogenesis:Purine metabolism:Metabolic pathways:Biosynthesis of secondary metabolites:ABC transporters:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:Function unknown:hsdM:purD:RNasePH:QueF-II:Defense mechanisms:RNA processing:Transcription:Restriction/modification:DNA metabolism:Purine ribonucleotide biosynthesis:Purines, pyrimidines, nucleosides, and nucleotides:Metabolism:Metabolism:Global:Membrane Transport:Environmental Information Processing:Poorly characterized:Nucleotide Metabolism:Metabolism:Cellular processes and signaling:Information storage and processing" 314 "Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases:NTP pyrophosphohydrolases including oxidative damage repair enzymes:Adenylate kinase and related kinases:Signal transduction histidine kinase:Predicted kinase:Predicted Rossmann fold nucleotide-binding protein involved in DNA uptake:Transcriptional regulator:Transcriptional regulators:Acetyltransferases, including N-acetylases of ribosomal proteins:Nucleotide transport and metabolism:Lipid transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:Replication, recombination and repair:Glycolysis / Gluconeogenesis:Tyrosine metabolism:Benzoate degradation:Pyruvate metabolism:Naphthalene degradation:Aminobenzoate degradation:Propanoate metabolism:Ethylbenzene degradation:Methane metabolism:Carbon fixation pathways in prokaryotes:Limonene and pinene degradation:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:General function prediction only:Signal transduction mechanisms:dprA:SASP_H:Intracellular trafficking, secretion, and vesicular transport:Poorly characterized:Carbohydrate Metabolism:Energy Metabolism:Amino Acid Metabolism:Metabolism of Terpenoids and Polyketides:Xenobiotics Biodegradation and Metabolism:Global:Metabolism:Cellular processes:DNA transformation:Sporulation and germination:Information storage and processing:Cellular processes and signaling:Metabolism:Metabolism" 315 "Cation transport ATPase:Phosphatidylserine synthase:Uncharacterized membrane protein:Transcriptional regulator:DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog:Beta-lactamase class C and other penicillin binding proteins:Predicted transcriptional regulators:Transcriptional regulators:Leucyl aminopeptidase (aminopeptidase T):Uncharacterized conserved protein:Predicted membrane protein:Predicted dienelactone hydrolase:Glycopeptide antibiotics resistance protein:Amino acid transport and metabolism:Lipid transport and metabolism:Transcription:Inorganic ion transport and metabolism:Glycine serine and threonine metabolism:Tyrosine metabolism:Benzoate degradation:Glycerophospholipid metabolism:Naphthalene degradation:Aminobenzoate degradation:Ethylbenzene degradation:Limonene and pinene degradation:Metabolic pathways:Microbial metabolism in diverse environments:RNA polymerase:General function prediction only:Function unknown:pssA:efflux_EmrB:ATPase_P-type:sigma70-ECF:Defense mechanisms:Other:Transport and binding proteins:Biosynthesis:Fatty acid and phospholipid metabolism:Metabolism:Metabolism:Global:Transcription:Genetic Information Processing:Xenobiotics Biodegradation and Metabolism:Metabolism of Terpenoids and Polyketides:Amino Acid Metabolism:Poorly characterized:Lipid Metabolism:Metabolism:Cellular processes and signaling:Information storage and processing" 316 "Predicted phosphatases:Signal transduction histidine kinase:Mannose-6-phosphate isomerase:Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain:Gamma-aminobutyrate permease and related permeases:Predicted transcriptional regulators:Predicted transcriptional regulators:Transcriptional regulators:Uncharacterized conserved protein:Putative NADPH-quinone reductase (modulator of drug activity B):Predicted permeases:Uncharacterized protein conserved in bacteria:Signal transduction histidine kinase:Uncharacterized protein conserved in bacteria:Amino acid transport and metabolism:Carbohydrate transport and metabolism:Transcription:Glyoxylate and dicarboxylate metabolism:Metabolic pathways:Two-component system:General function prediction only:Function unknown:Signal transduction mechanisms:LPXTG_anchor:HAD-SF-IA-v1:WXG100_ESAT6:Metabolism:Global:Signal Transduction:Environmental Information Processing:Cellular processes and signaling:Carbohydrate Metabolism:Metabolism:Poorly characterized:Metabolism:Information storage and processing:Other:Cell envelope:Enzymes of unknown specificity:Unknown function" 317 "Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II:Na+/H+ antiporter NhaD and related arsenite permeases:ABC-type proline/glycine betaine transport systems, periplasmic components:ABC-type oligopeptide transport system, periplasmic component:ABC-type proline/glycine betaine transport system, ATPase component:Amino acid transport and metabolism:Lipid transport and metabolism:Inorganic ion transport and metabolism:Fatty acid metabolism:Metabolic pathways:ABC transporters:Secondary metabolites biosynthesis, transport and catabolism:proV:exospore_TM:Transport and binding proteins:Lipid Metabolism:Environmental Information Processing:Membrane Transport:Global:Metabolism:Metabolism:Amino acids, peptides and amines:Metabolism" 318 "Predicted translation initiation factor 2B subunit, eIF-2B alpha/beta/delta family:Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases:ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component:ABC-type dipeptide/oligopeptide/nickel transport systems, permease components:Cystathionine beta-lyases/cystathionine gamma-synthases:ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component:ABC-type sugar transport system, ATPase component:ABC-type dipeptide/oligopeptide/nickel transport systems, permease components:Methionine synthase I, cobalamin-binding domain:Metal-dependent amidase/aminoacylase/carboxypeptidase:ABC-type sugar transport system, periplasmic component:ABC-type oligopeptide transport system, periplasmic component:Predicted kinase:Amino acid transport and metabolism:Carbohydrate transport and metabolism:Translation, ribosomal structure and biogenesis:Inorganic ion transport and metabolism:Cysteine and methionine metabolism:Selenocompound metabolism:One carbon pool by folate:Sulfur metabolism:Metabolic pathways:Biosynthesis of secondary metabolites:ABC transporters:General function prediction only:salvage_mtnA:oligo_HPY:MTRK:amidohydrolases:metH:salvage_mtnB:Poorly characterized:Energy Metabolism:Amino Acid Metabolism:Metabolism of Other Amino Acids:Metabolism of Cofactors and Vitamins:Environmental Information Processing:Membrane Transport:Global:Metabolism:Protein fate:Degradation of proteins, peptides, and glycopeptides:Transport and binding proteins:Amino acids, peptides and amines:Amino acid biosynthesis:Aspartate family:Information storage and processing:Metabolism:Metabolism" 319 "Energy production and conversion:Ribonucleotide reductase, alpha subunit:Superfamily I DNA and RNA helicases:5'-3' exonuclease (including N-terminal domain of PolI):Glycosyltransferases involved in cell wall biogenesis:ATPase components of ABC transporters with duplicated ATPase domains:Predicted hydrolase of the metallo-beta-lactamase superfamily:Asp-tRNAAsn/Glu-tRNAGln amidotransferase C subunit:Predicted GTPases:Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily:Predicted phosphate-binding enzymes, TIM-barrel fold:Protein involved in ribonucleotide reduction:Penicillin-binding protein-related factor A, putative recombinase:Predicted O-methyltransferase:Predicted O-methyltransferase:Predicted membrane protein:Membrane domain of membrane-anchored glycerophosphoryl diester phosphodiesterase:Predicted membrane protein:Nucleotide transport and metabolism:Translation, ribosomal structure and biogenesis:Replication, recombination and repair:Cell wall/membrane/envelope biogenesis:Purine metabolism:Pyrimidine metabolism:Phenylalanine metabolism:Glycerophospholipid metabolism:Aminoacyl-tRNA biosynthesis:Metabolic pathways:Biosynthesis of secondary metabolites:RNA degradation:Nucleotide excision repair:Mismatch repair:General function prediction only:Function unknown:gatC:TIGR00157:nrdI:recU:MG423:pcrA:GGGP-family:int_mem_ywzB:NrdE_NrdA:Poorly characterized:Lipid Metabolism:Nucleotide Metabolism:Amino Acid Metabolism:Genetic Information Processing:Translation:Folding Sorting and Degradation:Replication and Repair:Global:Metabolism:Purines, pyrimidines, nucleosides, and nucleotides:2'-Deoxyribonucleotide metabolism:DNA metabolism:DNA replication, recombination, and repair:Protein synthesis:tRNA aminoacylation:Translation factors:Hypothetical proteins:Conserved:Information storage and processing:Cellular processes and signaling:Metabolism:Metabolism" 320 "Energy production and conversion:Uroporphyrinogen-III methylase:Molybdopterin biosynthesis enzyme:Molybdopterin converting factor, large subunit:Flavodoxin reductases (ferredoxin-NADPH reductases) family 1:Nitrate reductase beta subunit:6Fe-6S prismane cluster-containing protein:NAD(P)H-nitrite reductase:Siroheme synthase (precorrin-2 oxidase/ferrochelatase domain):Uncharacterized conserved protein:Ferredoxin subunits of nitrite reductase and ring-hydroxylating dioxygenases:Nitrate reductase delta subunit:Nitrate reductase gamma subunit:Nitrate/nitrite transporter:Regulator of cell morphogenesis and NO signaling:Nitrate reductase alpha subunit:Cell cycle control, cell division, chromosome partitioning:Coenzyme transport and metabolism:Inorganic ion transport and metabolism:Porphyrin and chlorophyll metabolism:Nitrogen metabolism:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:Two-component system:Sulfur relay system:General function prediction only:Function unknown:molyb_syn:narI:narJ:cobA_cysG_Cterm:cysG_Nterm:narG:narH:hybrid_clust:nitri_red_nirB:nirD_assim_sml:FeS_repair_RIC:Poorly characterized:Metabolism:Cellular processes and signaling:Heme, porphyrin, and cobalamin:Other:Biosynthesis of cofactors, prosthetic groups, and carriers:Protein folding and stabilization:Protein fate:Anaerobic:Amino acids and amines:Energy metabolism:Nitrogen metabolism:Central intermediary metabolism:Metabolism:Global:Signal Transduction:Environmental Information Processing:Metabolism:Folding Sorting and Degradation:Genetic Information Processing:Metabolism of Cofactors and Vitamins:Energy Metabolism" 321 "Energy production and conversion:NADH:ubiquinone oxidoreductase 20 kD subunit and related Fe-S oxidoreductases:NADH:ubiquinone oxidoreductase subunit 11 or 4L (chain K):Na+-dependent transporters of the SNF family:NADH:ubiquinone oxidoreductase subunit 3 (chain A):NADH:ubiquinone oxidoreductase subunit 6 (chain J):NADH:ubiquinone oxidoreductase subunit 2 (chain N):Formate hydrogenlyase subunit 6/NADH:ubiquinone oxidoreductase 23 kD subunit (chain I):Type II secretory pathway, pseudopilin PulG:Zinc metalloprotease (elastase):Competence protein ComGC:Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain:Amino acid transport and metabolism:Cell motility:Oxidative phosphorylation:Metabolic pathways:General function prediction only:Signal transduction mechanisms:sensory_box:NDH_I_N:nuoB_fam:NuoI:IV_pilin_GFxxxE:spore_II_R:spore_V_AE:spore_III_AD:Intracellular trafficking, secretion, and vesicular transport:Cellular processes:Protein and peptide secretion and trafficking:Protein fate:Small molecule interactions:Regulatory functions:Electron transport:Energy metabolism:Metabolism:Metabolism:Global:Metabolism:Energy Metabolism:Poorly characterized:Cellular processes and signaling:Sporulation and germination" 322 "Energy production and conversion:Malate/lactate dehydrogenases:Succinyl-CoA synthetase, beta subunit:Succinyl-CoA synthetase, alpha subunit:Leucyl aminopeptidase:Citrate synthase:Glycine cleavage system protein P (pyridoxal-binding), N-terminal domain:Glycine cleavage system T protein (aminomethyltransferase):Succinate dehydrogenase/fumarate reductase, Fe-S protein subunit:Thioredoxin reductase:Isocitrate dehydrogenases:Phosphoglycerate mutase 1:Glycine cleavage system protein P (pyridoxal-binding), C-terminal domain:Succinate dehydrogenase/fumarate reductase, flavoprotein subunit:Cellulase M and related proteins:2'-5' RNA ligase:Transcriptional regulators:Succinate dehydrogenase/fumarate reductase, cytochrome b subunit:Predicted acyltransferase:Uncharacterized proteins involved in stress response, homologs of TerZ and putative cAMP-binding protein CABP1:Formyltetrahydrofolate synthetase:Amino acid transport and metabolism:Nucleotide transport and metabolism:Carbohydrate transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:Posttranslational modification, protein turnover, chaperones:Glycolysis / Gluconeogenesis:Citrate cycle (TCA cycle):Oxidative phosphorylation:Pyrimidine metabolism:Glycine serine and threonine metabolism:Glutathione metabolism:Pyruvate metabolism:Glyoxylate and dicarboxylate metabolism:Propanoate metabolism:Butanoate metabolism:C5-Branched dibasic acid metabolism:One carbon pool by folate:Methane metabolism:Carbon fixation pathways in prokaryotes:Nitrogen metabolism:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:General function prediction only:Signal transduction mechanisms:prok_nadp_idh:dhsB:gcvT:sucCoAbeta:sucCoAalpha:pgm_1:MalateDH_bact:cit_synth_II:sdhA_Bsu:sdhC_b558_fam:Global:Metabolism of Cofactors and Vitamins:Metabolism of Other Amino Acids:Amino Acid Metabolism:Nucleotide Metabolism:Energy Metabolism:Poorly characterized:Carbohydrate Metabolism:Metabolism:Cellular processes and signaling:Information storage and processing:TCA cycle:Amino acids and amines:Energy metabolism:Metabolism:Metabolism" 323 "Uncharacterized NAD(FAD)-dependent dehydrogenases:Amidases related to nicotinamidase:Arabinose efflux permease:Carbohydrate transport and metabolism:Tyrosine metabolism:Benzoate degradation:Naphthalene degradation:Aminobenzoate degradation:Ethylbenzene degradation:Limonene and pinene degradation:Microbial metabolism in diverse environments:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:psiM2_ORF9:Prophage functions:Metabolism:Poorly characterized:Global:Xenobiotics Biodegradation and Metabolism:Metabolism of Terpenoids and Polyketides:Metabolism:Amino Acid Metabolism:Metabolism:Mobile and extrachromosomal element functions" 324 "Biotin carboxylase:ABC-type amino acid transport/signal transduction systems, periplasmic component/domain:DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog:Phage head maturation protease:Amino acid transport and metabolism:Lipid transport and metabolism:Transcription:ABC transporters:RNA polymerase:General function prediction only:Signal transduction mechanisms:proheadase_HK97:maj_tail_phi13:sigma70-ECF:Information storage and processing:Transcription:Environmental Information Processing:Membrane Transport:Protein fate:Other:Mobile and extrachromosomal element functions:Prophage functions:Genetic Information Processing:Cellular processes and signaling:Metabolism:Poorly characterized" 325 "Lipoate-protein ligase A:UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N-acetylglucosamine-1-phosphate transferase:Rhodanese-related sulfurtransferase:Endonuclease IV:UDP-N-acetylmuramate-alanine ligase:Enzyme involved in the deoxyxylulose pathway of isoprenoid biosynthesis:Non-ribosomal peptide synthetase modules and related proteins:Cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes:D-alanine-D-alanine ligase and related ATP-grasp enzymes:Predicted Fe-S oxidoreductase:Predicted metal-binding, possibly nucleic acid-binding protein:Amino acid transport and metabolism:Coenzyme transport and metabolism:Lipid transport and metabolism:Replication, recombination and repair:Cell wall/membrane/envelope biogenesis:Inorganic ion transport and metabolism:D-Glutamine and D-glutamate metabolism:D-Alanine metabolism:Peptidoglycan biosynthesis:Thiamine metabolism:Lipoic acid metabolism:Terpenoid backbone biosynthesis:Metabolic pathways:Biosynthesis of secondary metabolites:Base excision repair:Sulfur relay system:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:nfo:ispG_gcpE:murC:D_ala_D_alaTIGR:TIGR01212:AA-adenyl-dom:Cellular processes and signaling:Metabolism of Other Amino Acids:Glycan Biosynthesis and Metabolism:Metabolism of Cofactors and Vitamins:Metabolism of Terpenoids and Polyketides:Genetic Information Processing:Folding Sorting and Degradation:Replication and Repair:Global:Metabolism:DNA metabolism:DNA replication, recombination, and repair:Unknown function:Enzymes of unknown specificity:Biosynthesis of cofactors, prosthetic groups, and carriers:Other:Cell envelope:Biosynthesis and degradation of murein sacculus and peptidoglycan:Information storage and processing:Metabolism:Metabolism:Poorly characterized" 326 "Energy production and conversion:Glucose-6-phosphate isomerase:Fructose/tagatose bisphosphate aldolase:Dihydroxynaphthoic acid synthase:DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32):Membrane protein TerC, possibly involved in tellurium resistance:Phosphomannomutase:Na+/alanine symporter:Ferredoxin:Lysyl-tRNA synthetase (class II):UDP-glucose pyrophosphorylase:Uncharacterized conserved protein:Disulfide bond formation protein DsbB:Predicted membrane protein:Uncharacterized protein conserved in bacteria:Uncharacterized conserved small protein:Amino acid transport and metabolism:Carbohydrate transport and metabolism:Coenzyme transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:Cell wall/membrane/envelope biogenesis:Posttranslational modification, protein turnover, chaperones:Inorganic ion transport and metabolism:Glycolysis / Gluconeogenesis:Pentose phosphate pathway:Pentose and glucuronate interconversions:Fructose and mannose metabolism:Galactose metabolism:Ubiquinone and other terpenoid-quinone biosynthesis:Purine metabolism:Starch and sucrose metabolism:Amino sugar and nucleotide sugar metabolism:Streptomycin biosynthesis:Methane metabolism:Aminoacyl-tRNA biosynthesis:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:RNA polymerase:Function unknown:cbbA:lysS_bact:agcS:galU:menB:RpoD_Cterm:R_switched_YkoY:Cellular processes and signaling:Carbohydrate Metabolism:Energy Metabolism:Nucleotide Metabolism:Metabolism of Cofactors and Vitamins:Biosynthesis of Other Secondary Metabolites:Genetic Information Processing:Transcription:Translation:Global:Metabolism:Energy metabolism:Glycolysis/gluconeogenesis:Transcription:Transcription factors:Protein synthesis:tRNA aminoacylation:Biosynthesis of cofactors, prosthetic groups, and carriers:Menaquinone and ubiquinone:Cell envelope:Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides:Information storage and processing:Metabolism:Metabolism:Poorly characterized" 327 "3-methyladenine DNA glycosylase/8-oxoguanine DNA glycosylase:ABC-type antimicrobial peptide transport system, permease component:MoxR-like ATPases:Membrane-fusion protein:ABC-type antimicrobial peptide transport system, ATPase component:Amidases related to nicotinamidase:Acetyltransferases, including N-acetylases of ribosomal proteins:Uncharacterized conserved protein (some members contain a von Willebrand factor type A (vWA) domain):FOG: GGDEF domain:Sugar phosphate permease:ABC-type oligopeptide transport system, periplasmic component:Predicted acetyltransferase involved in intracellular survival and related acetyltransferases:Predicted integral membrane protein:Predicted metal-dependent enzyme of the double-stranded beta helix superfamily:Amino acid transport and metabolism:Carbohydrate transport and metabolism:Translation, ribosomal structure and biogenesis:Replication, recombination and repair:Cell wall/membrane/envelope biogenesis:Biosynthesis of siderophore group nonribosomal peptides:Biosynthesis of secondary metabolites:ABC transporters:Base excision repair:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:Function unknown:Signal transduction mechanisms:GGDEF:Defense mechanisms:Metabolism:Poorly characterized:Metabolism:Cellular processes and signaling:Information storage and processing:Other:Signal transduction:Metabolism:Global:Membrane Transport:Environmental Information Processing:Replication and Repair:Genetic Information Processing:Metabolism of Terpenoids and Polyketides" 328 "Energy production and conversion:7-keto-8-aminopelargonate synthetase and related enzymes:Acetyl-CoA acetyltransferase:Glycine cleavage system protein P (pyridoxal-binding), N-terminal domain:Glycine cleavage system T protein (aminomethyltransferase):Nucleoside-diphosphate-sugar epimerases:Succinate dehydrogenase/fumarate reductase, Fe-S protein subunit:Glycine cleavage system protein P (pyridoxal-binding), C-terminal domain:Enoyl-CoA hydratase/carnithine racemase:Succinate dehydrogenase/fumarate reductase, flavoprotein subunit:3-hydroxyacyl-CoA dehydrogenase:Transcriptional regulator:2'-5' RNA ligase:Acetyltransferases, including N-acetylases of ribosomal proteins:Acyl-CoA dehydrogenases:Succinate dehydrogenase/fumarate reductase, cytochrome b subunit:Electron transfer flavoprotein, beta subunit:Predicted acyltransferase:Enterochelin esterase and related enzymes:Aminoglycoside N3'-acetyltransferase:Amino acid transport and metabolism:Carbohydrate transport and metabolism:Coenzyme transport and metabolism:Lipid transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:Cell wall/membrane/envelope biogenesis:Inorganic ion transport and metabolism:Citrate cycle (TCA cycle):Fatty acid metabolism:Oxidative phosphorylation:Glycine serine and threonine metabolism:Valine leucine and isoleucine degradation:Geraniol degradation:Benzoate degradation:alpha-Linolenic acid metabolism:Naphthalene degradation:Ethylbenzene degradation:Butanoate metabolism:One carbon pool by folate:Carbon fixation pathways in prokaryotes:Nitrogen metabolism:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:General function prediction only:dhsB:gcvT:sdhA_Bsu:gly_Cac_T_rel:AcCoA-C-Actrans:sdhC_b558_fam:Defense mechanisms:Fatty acid and phospholipid metabolism:TCA cycle:Amino acids and amines:Energy metabolism:Other:Information storage and processing:Cellular processes and signaling:Metabolism:Poorly characterized:Metabolism:Metabolism:Global:Xenobiotics Biodegradation and Metabolism:Metabolism of Terpenoids and Polyketides:Metabolism of Cofactors and Vitamins:Amino Acid Metabolism:Lipid Metabolism:Energy Metabolism:Carbohydrate Metabolism" 329 "Energy production and conversion:Thymidylate kinase:Lactoylglutathione lyase and related lyases:Ketopantoate hydroxymethyltransferase:Panthothenate synthetase:Glycerol kinase:Glycerol-3-phosphate dehydrogenase:Signal transduction histidine kinase:Small-conductance mechanosensitive channel:Predicted permeases:Phosphopantetheinyl transferase (holo-ACP synthase):Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain:Aspartate 1-decarboxylase:Putative transcriptional regulator, homolog of Bvg accessory factor:Predicted metal-dependent hydrolases related to alanyl-tRNA synthetase HxxxH domain:Predicted membrane protein:Amino acid transport and metabolism:Nucleotide transport and metabolism:Coenzyme transport and metabolism:Lipid transport and metabolism:Transcription:Cell wall/membrane/envelope biogenesis:Pyrimidine metabolism:beta-Alanine metabolism:Glycerolipid metabolism:Glycerophospholipid metabolism:Pantothenate and CoA biosynthesis:Metabolic pathways:Biosynthesis of secondary metabolites:General function prediction only:Function unknown:Signal transduction mechanisms:panC:DTMP_kinase:panB:panD:acpS:baf:glycerol_kin:TIGR03943:Purines, pyrimidines, nucleosides, and nucleotides:Biosynthesis:Fatty acid and phospholipid metabolism:Other:Energy metabolism:Metabolism:Metabolism:Global:Metabolism of Cofactors and Vitamins:Metabolism of Other Amino Acids:Nucleotide Metabolism:Poorly characterized:Lipid Metabolism:Metabolism:Cellular processes and signaling:Information storage and processing:Pantothenate and coenzyme A:Biosynthesis of cofactors, prosthetic groups, and carriers:Nucleotide and nucleoside interconversions" 330 "Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase:Aspartokinases:Putative intracellular protease/amidase:Predicted transcriptional regulators:Predicted thioesterase:Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases):Gamma-aminobutyrate permease and related permeases:ABC-type multidrug transport system, ATPase component:Predicted metal-dependent hydrolase:Uncharacterized conserved protein:Amino acid transport and metabolism:Coenzyme transport and metabolism:Lipid transport and metabolism:Transcription:Fatty acid biosynthesis:Glycine serine and threonine metabolism:Cysteine and methionine metabolism:Valine leucine and isoleucine degradation:Valine leucine and isoleucine biosynthesis:Lysine biosynthesis:Pantothenate and CoA biosynthesis:Biosynthesis of unsaturated fatty acids:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:ABC transporters:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:Function unknown:asp_kin_monofn:ilvE_I:Defense mechanisms:Poorly characterized:Lipid Metabolism:Amino Acid Metabolism:Metabolism of Cofactors and Vitamins:Environmental Information Processing:Membrane Transport:Global:Metabolism:Amino acid biosynthesis:Aspartate family:Pyruvate family:Information storage and processing:Cellular processes and signaling:Metabolism:Metabolism" 331 "ABC-type Fe3+-siderophore transport system, permease component:ABC-type Fe3+-hydroxamate transport system, periplasmic component:Non-ribosomal peptide synthetase modules and related proteins:Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases):ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components:Isochorismate synthase:Isochorismate hydrolase:Sugar phosphate permease:Predicted hydrolase of the alpha/beta superfamily:Uncharacterized protein conserved in bacteria:Carbohydrate transport and metabolism:Coenzyme transport and metabolism:Lipid transport and metabolism:Inorganic ion transport and metabolism:Ubiquinone and other terpenoid-quinone biosynthesis:Biosynthesis of siderophore group nonribosomal peptides:Metabolic pathways:Biosynthesis of secondary metabolites:ABC transporters:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:Function unknown:isochor_syn:efflux_EmrB:AA-adenyl-dom:Metabolism:Metabolism of Cofactors and Vitamins:Metabolism of Terpenoids and Polyketides:Environmental Information Processing:Membrane Transport:Global:Metabolism:Transport and binding proteins:Other:Biosynthesis of cofactors, prosthetic groups, and carriers:Menaquinone and ubiquinone:Metabolism:Poorly characterized" 332 "Sulfite reductase, beta subunit (hemoprotein):3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase and related enzymes:ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component:Adenylylsulfate kinase and related kinases:ABC-type nitrate/sulfonate/bicarbonate transport system, permease component:ABC-type dipeptide/oligopeptide/nickel transport systems, permease components:Predicted phosphoesterase:ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components:Predicted permeases:ABC-type dipeptide transport system, periplasmic component:ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component:ABC-type dipeptide/oligopeptide/nickel transport systems, permease components:ATP sulfurylase (sulfate adenylyltransferase):ABC-type sulfate transport system, permease component:Amino acid transport and metabolism:Coenzyme transport and metabolism:Inorganic ion transport and metabolism:Purine metabolism:Selenocompound metabolism:Nitrogen metabolism:Sulfur metabolism:Metabolic pathways:Microbial metabolism in diverse environments:ABC transporters:General function prediction only:sopT:cysH:apsK:3a0106s02:3a0106s03:oligo_HPY:SsuA_fam:Anions:Amino acids, peptides and amines:Transport and binding proteins:Sulfur metabolism:Central intermediary metabolism:Metabolism:Metabolism:Global:Membrane Transport:Environmental Information Processing:Metabolism of Other Amino Acids:Nucleotide Metabolism:Poorly characterized:Energy Metabolism:Metabolism:Other" 333 "Lysine efflux permease:Acetyltransferases, including N-acetylases of ribosomal proteins:Transcriptional regulators:Uncharacterized protein conserved in bacteria:O-Methyltransferase involved in polyketide biosynthesis:Uncharacterized conserved protein:Translation, ribosomal structure and biogenesis:Transcription:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:Function unknown:mthyl_TIGR00027:Poorly characterized:Metabolism:Information storage and processing:Enzymes of unknown specificity:Unknown function" 334 "ABC-type branched-chain amino acid transport systems, ATPase component:Ribose/xylose/arabinose/galactoside ABC-type transport systems, permease components:Inosine-uridine nucleoside N-ribohydrolase:Predicted transcriptional regulator:Sortase (surface protein transpeptidase):Uncharacterized membrane protein:Amino acid transport and metabolism:Nucleotide transport and metabolism:Carbohydrate transport and metabolism:Transcription:Cell wall/membrane/envelope biogenesis:Purine metabolism:Nicotinate and nicotinamide metabolism:Metabolic pathways:ABC transporters:Function unknown:sortase_fam:spore_SleB:Sporulation and germination:Nucleotide Metabolism:Metabolism of Cofactors and Vitamins:Environmental Information Processing:Membrane Transport:Global:Metabolism:Protein fate:Protein and peptide secretion and trafficking:Cellular processes:Metabolism:Information storage and processing:Cellular processes and signaling:Metabolism:Poorly characterized" 335 "Energy production and conversion:Molecular chaperone (small heat shock protein):Fumarase:Co-chaperonin GroES (HSP10):Fe-S oxidoreductase:Fe2+ transport system protein B:Peroxiredoxin:Thioredoxin reductase:ATPases with chaperone activity, ATP-binding subunit:Predicted hydrolases of the HAD superfamily:Predicted transcriptional regulators:Fe2+/Zn2+ uptake regulation proteins:Protease subunit of ATP-dependent Clp proteases:Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases):Transcriptional regulators:Fe2+ transport system protein A:Predicted membrane-bound metal-dependent hydrolases:Cation transport ATPase:Predicted oxidoreductase related to nitroreductase:Alkyl hydroperoxide reductase, large subunit:Arginine kinase:Uncharacterized protein with conserved CXXC pairs:Transcriptional repressor of class III stress genes:Amino acid transport and metabolism:Lipid transport and metabolism:Transcription:Posttranslational modification, protein turnover, chaperones:Inorganic ion transport and metabolism:Citrate cycle (TCA cycle):Fatty acid biosynthesis:Pyrimidine metabolism:Glyoxylate and dicarboxylate metabolism:Carbon fixation pathways in prokaryotes:Biosynthesis of unsaturated fatty acids:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:Function unknown:Cof-subfamily:clpP:fumC_II:ATPase_P-type:AhpC:AhpF:chaperone_ClpB:Intracellular trafficking, secretion, and vesicular transport:Adaptations to atypical conditions:Cellular processes:Degradation of proteins, peptides, and glycopeptides:Protein folding and stabilization:Protein fate:TCA cycle:Energy metabolism:Metabolism:Metabolism:Global:Nucleotide Metabolism:Lipid Metabolism:Energy Metabolism:Carbohydrate Metabolism:Poorly characterized:Metabolism:Cellular processes and signaling:Information storage and processing:Enzymes of unknown specificity:Unknown function" 336 "Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases:Cell division protein FtsI/penicillin-binding protein 2:Transcriptional regulator:Acetyltransferases, including N-acetylases of ribosomal proteins:Uncharacterized membrane protein, possible Na+ channel or pump:Arabinose efflux permease:Carbohydrate transport and metabolism:Lipid transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:Cell wall/membrane/envelope biogenesis:Glycolysis / Gluconeogenesis:Tyrosine metabolism:Benzoate degradation:Pyruvate metabolism:Naphthalene degradation:Aminobenzoate degradation:Propanoate metabolism:Ethylbenzene degradation:Methane metabolism:Carbon fixation pathways in prokaryotes:Limonene and pinene degradation:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:General function prediction only:Information storage and processing:Metabolism:Metabolism:Global:Xenobiotics Biodegradation and Metabolism:Metabolism of Terpenoids and Polyketides:Amino Acid Metabolism:Energy Metabolism:Cellular processes and signaling:Carbohydrate Metabolism:Metabolism:Poorly characterized" 337 "Energy production and conversion:3-methyladenine DNA glycosylase/8-oxoguanine DNA glycosylase:Membrane protease subunits, stomatin/prohibitin homologs:Methylated DNA-protein cysteine methyltransferase:NTP pyrophosphohydrolases including oxidative damage repair enzymes:Cell division protein FtsI/penicillin-binding protein 2:Predicted transcriptional regulators:Imidazolonepropionase and related amidohydrolases:Na+/H+-dicarboxylate symporters:Transcriptional regulators, similar to M. xanthus CarD:Ferritin-like protein:Transcriptional regulators:Adenosine deaminase:Uncharacterized conserved protein:Histidine ammonia-lyase:Urocanate hydratase:Glycopeptide antibiotics resistance protein:Uncharacterized protein conserved in bacteria:Uncharacterized protein conserved in bacteria:Amino acid transport and metabolism:Nucleotide transport and metabolism:Transcription:Replication, recombination and repair:Cell wall/membrane/envelope biogenesis:Posttranslational modification, protein turnover, chaperones:Inorganic ion transport and metabolism:Histidine metabolism:Porphyrin and chlorophyll metabolism:Nitrogen metabolism:Metabolic pathways:Base excision repair:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:Function unknown:ogt:hutI:hutH:hutU:Defense mechanisms:DNA metabolism:Amino acids and amines:Energy metabolism:DNA replication, recombination, and repair:Information storage and processing:Cellular processes and signaling:Metabolism:Metabolism:Metabolism:Global:Poorly characterized:Replication and Repair:Genetic Information Processing:Metabolism of Cofactors and Vitamins:Amino Acid Metabolism:Energy Metabolism" 338 "Uroporphyrinogen-III methylase:Diaminopimelate decarboxylase:Predicted translation initiation factor 2B subunit, eIF-2B alpha/beta/delta family:Predicted redox protein, regulator of disulfide bond formation:Nucleoside-diphosphate-sugar epimerases:Homoserine dehydrogenase:Zn-dependent hydrolases, including glyoxylases:Rhodanese-related sulfurtransferase:Methionine synthase I (cobalamin-dependent), methyltransferase domain:Predicted permeases:ABC-type sugar transport system, ATPase component:Amidases related to nicotinamidase:Methionine synthase I, cobalamin-binding domain:ABC-type sugar transport system, periplasmic component:Homoserine trans-succinylase:Uncharacterized conserved protein:Amino acid transport and metabolism:Carbohydrate transport and metabolism:Coenzyme transport and metabolism:Translation, ribosomal structure and biogenesis:Cell wall/membrane/envelope biogenesis:Posttranslational modification, protein turnover, chaperones:Inorganic ion transport and metabolism:Glycine serine and threonine metabolism:Cysteine and methionine metabolism:Lysine biosynthesis:One carbon pool by folate:Porphyrin and chlorophyll metabolism:Sulfur metabolism:Biosynthesis of siderophore group nonribosomal peptides:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:Function unknown:salvage_mtnA:metA:lysA:cobA_cysG_Cterm:metH:Poorly characterized:Metabolism:Cellular processes and signaling:Information storage and processing:Heme, porphyrin, and cobalamin:Biosynthesis of cofactors, prosthetic groups, and carriers:Aspartate family:Amino acid biosynthesis:Metabolism:Metabolism:Global:Metabolism of Terpenoids and Polyketides:Metabolism of Cofactors and Vitamins:Amino Acid Metabolism:Energy Metabolism" 339 "Predicted S-adenosylmethionine-dependent methyltransferase:Nucleoside-diphosphate-sugar epimerases:ABC-type dipeptide/oligopeptide/nickel transport systems, permease components:Uncharacterized membrane protein, putative virulence factor:ABC-type amino acid transport system, permease component:Na+/alanine symporter:Phosphotransferase system cellobiose-specific component IIB:Predicted membrane protein:Uncharacterized protein conserved in bacteria:Amino acid transport and metabolism:Carbohydrate transport and metabolism:Cell wall/membrane/envelope biogenesis:Inorganic ion transport and metabolism:ABC transporters:Phosphotransferase system (PTS):General function prediction only:Function unknown:agcS:pts-lac:HEQRo_perm_3TM:spore_ylbJ:spore_V_B:xxxLxxG_by_4:Metabolism:Membrane Transport:Transport and binding proteins:Amino acids, peptides and amines:Cellular processes:Sporulation and germination:Signal transduction:PTS:Cellular processes and signaling:Environmental Information Processing:Poorly characterized" 340 "Permeases of the drug/metabolite transporter (DMT) superfamily:ABC-type amino acid transport system, permease component:ABC-type amino acid transport/signal transduction systems, periplasmic component/domain:Peroxiredoxin:Lysine 2,3-aminomutase:Acetyltransferases, including N-acetylases of ribosomal proteins:Uncharacterized protein conserved in bacteria:Sugar phosphate permease:Endoglucanase Y:Amino acid transport and metabolism:Carbohydrate transport and metabolism:Translation, ribosomal structure and biogenesis:Posttranslational modification, protein turnover, chaperones:Lysine degradation:ABC transporters:General function prediction only:Function unknown:Signal transduction mechanisms:TIGR00238:HEQRo_perm_3TM:YokU_near_AblA:Metabolism:Amino Acid Metabolism:Environmental Information Processing:Membrane Transport:Energy metabolism:Electron transport:Transport and binding proteins:Amino acids, peptides and amines:Unknown function:General:Information storage and processing:Cellular processes and signaling:Metabolism:Poorly characterized" 341 "Energy production and conversion:Serine-pyruvate aminotransferase/archaeal aspartate aminotransferase:Zn-dependent hydrolases, including glyoxylases:NTP pyrophosphohydrolases including oxidative damage repair enzymes:Transcriptional regulator:Uncharacterized membrane-associated protein:Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily):Permeases of the drug/metabolite transporter (DMT) superfamily:Predicted xylanase/chitin deacetylase:N-acetylmuramoyl-L-alanine amidase:ADP-ribose pyrophosphatase:Na+/H+ antiporter NhaD and related arsenite permeases:ABC-type multidrug transport system, ATPase component:Threonine dehydratase:Uncharacterized conserved protein:Erythromycin esterase homolog:H+/citrate symporter:Uncharacterized conserved protein:Predicted ABC-type exoprotein transport system, permease component:Membrane protein involved in cytochrome C biogenesis:Amino acid transport and metabolism:Nucleotide transport and metabolism:Carbohydrate transport and metabolism:Transcription:Replication, recombination and repair:Cell wall/membrane/envelope biogenesis:Posttranslational modification, protein turnover, chaperones:Inorganic ion transport and metabolism:Glycine serine and threonine metabolism:Valine leucine and isoleucine biosynthesis:Tyrosine metabolism:Benzoate degradation:Naphthalene degradation:Aminobenzoate degradation:Ethylbenzene degradation:Limonene and pinene degradation:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:ABC transporters:General function prediction only:Function unknown:citMHS:ilvA_1Cterm:spore_ytfJ:Intracellular trafficking, secretion, and vesicular transport:Defense mechanisms:Poorly characterized:Amino Acid Metabolism:Metabolism of Terpenoids and Polyketides:Xenobiotics Biodegradation and Metabolism:Environmental Information Processing:Membrane Transport:Global:Metabolism:Transport and binding proteins:Carbohydrates, organic alcohols, and acids:Cellular processes:Sporulation and germination:Amino acid biosynthesis:Pyruvate family:Information storage and processing:Cellular processes and signaling:Metabolism:Metabolism" 342 "Predicted membrane protein:Regulators of stationary/sporulation gene expression:Transcription:Function unknown:lp_hng_hel_AbrB:T7SS_EssA_Firm:T7_esaA_Nterm:Information storage and processing:Poorly characterized:Protein fate:Regulatory functions:DNA interactions:Protein and peptide secretion and trafficking" 343 "Site-specific DNA methylase:Uncharacterized conserved protein:Predicted Zn-dependent hydrolases of the beta-lactamase fold:Predicted membrane protein:Lysophospholipase L1 and related esterases:Arabinose efflux permease:SH3 domain protein:Uncharacterized protein conserved in bacteria:Amino acid transport and metabolism:Carbohydrate transport and metabolism:Replication, recombination and repair:Cysteine and methionine metabolism:Metabolic pathways:General function prediction only:Function unknown:Signal transduction mechanisms:dcm:DNA_bind_RsfA:Poorly characterized:Amino Acid Metabolism:Global:Metabolism:DNA metabolism:DNA replication, recombination, and repair:Cellular processes:Sporulation and germination:Information storage and processing:Cellular processes and signaling:Metabolism:Metabolism" 344 "Imidazoleglycerol-phosphate synthase:Thermophilic glucose-6-phosphate isomerase and related metalloenzymes:Uncharacterized conserved protein:ABC-type phosphate/phosphonate transport system, periplasmic component:Amino acid transport and metabolism:Carbohydrate transport and metabolism:Inorganic ion transport and metabolism:Histidine metabolism:Glyoxylate and dicarboxylate metabolism:Metabolic pathways:Biosynthesis of secondary metabolites:ABC transporters:General function prediction only:Function unknown:hisF:3A0109s03R:bicupin_oxalic:Transport and binding proteins:Carbohydrate Metabolism:Amino Acid Metabolism:Environmental Information Processing:Membrane Transport:Global:Metabolism:Metabolism:Anions:Amino acid biosynthesis:Histidine family:Metabolism:Poorly characterized" 345 "Predicted enzyme with a TIM-barrel fold:Recombinational DNA repair protein (RecF pathway):6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase:Uncharacterized conserved protein:K+ transport systems, NAD-binding component:Uncharacterized protein conserved in bacteria:Predicted integral membrane protein:Actin-like ATPase involved in cell division:Predicted transcriptional regulators containing the CopG/Arc/MetJ DNA-binding domain and a metal-binding domain:Predicted HD superfamily hydrolase:Uncharacterized protein conserved in bacteria:Uncharacterized conserved protein:Predicted P-loop-containing kinase:Uncharacterized protein conserved in bacteria:Growth inhibitor:Uncharacterized protein with SCP/PR1 domains:Cell cycle control, cell division, chromosome partitioning:Carbohydrate transport and metabolism:Transcription:Replication, recombination and repair:Inorganic ion transport and metabolism:Amino sugar and nucleotide sugar metabolism:Metabolic pathways:Homologous recombination:General function prediction only:Function unknown:Signal transduction mechanisms:TIGR00044:DNA_YbaB_EbfC:HDIG:nagB:recR:MG103:TIGR00726:ftsA:CofD_related:General:Carbohydrate Metabolism:Genetic Information Processing:Replication and Repair:Global:Metabolism:Central intermediary metabolism:Amino sugars:DNA metabolism:DNA replication, recombination, and repair:Cellular processes:Cell division:Hypothetical proteins:Conserved:Unknown function:Enzymes of unknown specificity:Metabolism:Information storage and processing:Cellular processes and signaling:Metabolism:Poorly characterized" 346 "Energy production and conversion:Polyprenyltransferase (cytochrome oxidase assembly factor):Predicted membrane metal-binding protein:Predicted transcriptional regulators:Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1:N-acetylglutamate synthase and related acetyltransferases:Hemolysins and related proteins containing CBS domains:ABC-type Na+ efflux pump, permease component:Sugar phosphate permease:ABC-type uncharacterized transport system, ATPase component:Amino acid transport and metabolism:Carbohydrate transport and metabolism:Coenzyme transport and metabolism:Transcription:Posttranslational modification, protein turnover, chaperones:Inorganic ion transport and metabolism:Oxidative phosphorylation:Porphyrin and chlorophyll metabolism:Metabolic pathways:Biosynthesis of secondary metabolites:General function prediction only:ComEC_N-term:cyoE_ctaB:Poorly characterized:Energy Metabolism:Metabolism of Cofactors and Vitamins:Global:Metabolism:Unknown function:General:Biosynthesis of cofactors, prosthetic groups, and carriers:Heme, porphyrin, and cobalamin:Information storage and processing:Cellular processes and signaling:Metabolism:Metabolism" 347 "Energy production and conversion:Non-ribosomal peptide synthetase modules and related proteins:Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM/CutM homologs:Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL homologs:Thiamine pyrophosphokinase:Xanthine and CO dehydrogenases maturation factor, XdhC/CoxF family:Uncharacterized MobA-related protein:Phosphopantetheinyl transferase:Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain:Predicted molecular chaperone distantly related to HSP70-fold metalloproteases:Lyzozyme M1 (1,4-beta-N-acetylmuramidase):Coenzyme transport and metabolism:Transcription:Cell wall/membrane/envelope biogenesis:Posttranslational modification, protein turnover, chaperones:Purine metabolism:Thiamine metabolism:Metabolic pathways:Microbial metabolism in diverse environments:Two-component system:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:Signal transduction mechanisms:pantethn_trn:2A0309:thi_PPkinase:DnaD_dom:AA-adenyl-dom:spore_III_AB:pucB:Metabolism:Nucleotide Metabolism:Metabolism of Cofactors and Vitamins:Environmental Information Processing:Signal Transduction:Global:Metabolism:Protein fate:Protein modification and repair:Transport and binding proteins:Amino acids, peptides and amines:Cellular processes:Sporulation and germination:Mobile and extrachromosomal element functions:Prophage functions:Biosynthesis of cofactors, prosthetic groups, and carriers:Thiamine:Information storage and processing:Cellular processes and signaling:Metabolism:Poorly characterized" 348 "Ribosomal protein L22:Ribosomal protein S3:Ribosomal protein L14:Ribosomal protein L5:Ribosomal protein S8:Ribosomal protein L6P/L9E:Ribosomal protein S5:Ribosomal protein S17:Ribosomal protein L16/L10E:Ribosomal protein L24:Ribosomal protein S14:Ribosomal protein L15:Ribosomal protein L29:Ribosomal protein L18:Ribosomal protein L30/L7E:Translation, ribosomal structure and biogenesis:Ribosome:L29:L18_bact:rpsC_bact:rpsE_bact:rplV_bact:rplN_bact:rplO_bact:rplX_bact:rplP_bact:rpmD_bact:S17_bact:L6_bact:Information storage and processing:Translation:Protein synthesis:Ribosomal proteins: synthesis and modification:Genetic Information Processing" 349 "Energy production and conversion:Glutamine phosphoribosylpyrophosphate amidotransferase:SAM-dependent methyltransferases:ABC-type sulfate transport system, permease component:Uncharacterized membrane-associated protein:Metal-dependent amidase/aminoacylase/carboxypeptidase:Siroheme synthase (precorrin-2 oxidase/ferrochelatase domain):Acetyltransferases, including N-acetylases of ribosomal proteins:Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases:Nucleotide transport and metabolism:Coenzyme transport and metabolism:Translation, ribosomal structure and biogenesis:Posttranslational modification, protein turnover, chaperones:Purine metabolism:Alanine aspartate and glutamate metabolism:Arginine and proline metabolism:Porphyrin and chlorophyll metabolism:Metabolic pathways:Biosynthesis of secondary metabolites:ABC transporters:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:Function unknown:3a0106s02:purF:cysG_Nterm:amidohydrolases:BioC:alk_sulf_monoox:Information storage and processing:Nucleotide Metabolism:Amino Acid Metabolism:Metabolism of Cofactors and Vitamins:Environmental Information Processing:Membrane Transport:Global:Metabolism:Central intermediary metabolism:Sulfur metabolism:Purines, pyrimidines, nucleosides, and nucleotides:Purine ribonucleotide biosynthesis:Protein fate:Degradation of proteins, peptides, and glycopeptides:Transport and binding proteins:Anions:Biosynthesis of cofactors, prosthetic groups, and carriers:Biotin:Heme, porphyrin, and cobalamin:Metabolism:Cellular processes and signaling:Metabolism:Poorly characterized" 350 "Methionine aminopeptidase:Translation elongation factor P (EF-P)/translation initiation factor 5A (eIF-5A):Predicted RNA binding protein (contains ribosomal protein S1 domain):Uncharacterized conserved protein:Cold shock proteins:Uncharacterized protein conserved in bacteria:Predicted transcriptional regulators:Arginine repressor:Predicted HD-superfamily hydrolase:Uncharacterized conserved protein:Uncharacterized protein conserved in bacteria:Response regulator of citrate/malate metabolism:Gas vesicle protein:Translation, ribosomal structure and biogenesis:Transcription:Two-component system:General function prediction only:Function unknown:Signal transduction mechanisms:efp:met_pdase_I:argR_whole:spore_0_A:Protein synthesis:DNA interactions:Regulatory functions:Sporulation and germination:Signal Transduction:Information storage and processing:Cellular processes and signaling:Poorly characterized:Environmental Information Processing:Cellular processes:Protein modification and repair:Protein fate:Translation factors" 351 "Energy production and conversion:Excinuclease ATPase subunit:NAD-dependent DNA ligase (contains BRCT domain type II):Nuclease subunit of the excinuclease complex:Acetyltransferases:ATPase components of ABC transporters with duplicated ATPase domains:Helicase subunit of the DNA excision repair complex:Phosphoenolpyruvate synthase/pyruvate phosphate dikinase:ABC-type dipeptide/oligopeptide/nickel transport systems, permease components:F0F1-type ATP synthase, subunit b:Predicted xylanase/chitin deacetylase:Predicted ATPase or kinase:Inactive homolog of metal-dependent proteases, putative molecular chaperone:DNA replication protein:Predicted membrane protein:Acetyltransferases, including N-acetylases of ribosomal proteins:Predicted transcriptional regulator:UV damage repair endonuclease:Amino acid transport and metabolism:Carbohydrate transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:Replication, recombination and repair:Posttranslational modification, protein turnover, chaperones:Inorganic ion transport and metabolism:Tyrosine metabolism:Benzoate degradation:Pyruvate metabolism:Naphthalene degradation:Aminobenzoate degradation:Ethylbenzene degradation:Methane metabolism:Carbon fixation pathways in prokaryotes:Limonene and pinene degradation:Metabolic pathways:Microbial metabolism in diverse environments:ABC transporters:DNA replication:Base excision repair:Nucleotide excision repair:Mismatch repair:General function prediction only:Function unknown:HI0065_YjeE:uvrC:dnlj:uvde:uvra:uvrb:rimI:spore_gerQ:spo_ytxC:xxxLxxG_by_4:bact_YeaZ:Environmental Information Processing:Metabolism:Replication and Repair:Genetic Information Processing:Xenobiotics Biodegradation and Metabolism:Metabolism of Terpenoids and Polyketides:Amino Acid Metabolism:Energy Metabolism:DNA metabolism:Carbohydrate Metabolism:DNA replication, recombination, and repair:Protein synthesis:Ribosomal proteins: synthesis and modification:Cellular processes:Sporulation and germination:Unknown function:Enzymes of unknown specificity:Information storage and processing:Cellular processes and signaling:Metabolism:Poorly characterized:Metabolism:Global:Membrane Transport" 352 "Amino acid transporters:Type II secretory pathway, pullulanase PulA and related glycosidases:DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog:Amino acid transport and metabolism:Carbohydrate transport and metabolism:Transcription:RNA polymerase:pulA_typeI:sigma70-ECF:Metabolism:Transcription:Information storage and processing:Genetic Information Processing" 353 "Parvulin-like peptidyl-prolyl isomerase:Acyl carrier protein phosphodiesterase:Mismatch repair ATPase (MutS family):Predicted transcriptional regulators:Chitinase:Carbohydrate transport and metabolism:Lipid transport and metabolism:Transcription:Replication, recombination and repair:Posttranslational modification, protein turnover, chaperones:Amino sugar and nucleotide sugar metabolism:Mismatch repair:Replication and Repair:Genetic Information Processing:Metabolism:Carbohydrate Metabolism:Metabolism:Cellular processes and signaling:Information storage and processing" 354 "Phosphoribosylamine-glycine ligase:ABC-type uncharacterized transport system, permease component:Uncharacterized membrane-associated protein:Uncharacterized membrane protein:Transcriptional regulator:Predicted transcriptional regulators:Acetyltransferases, including N-acetylases of ribosomal proteins:Uncharacterized host factor I protein:Predicted membrane protein:Predicted drug exporters of the RND superfamily:Arabinose efflux permease:Predicted membrane protein:Uncharacterized conserved protein:Predicted symporter:Nucleotide transport and metabolism:Carbohydrate transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:Purine metabolism:Metabolic pathways:Biosynthesis of secondary metabolites:RNA degradation:General function prediction only:Function unknown:TIGR00245:sss:purD:Hfq:Conserved:Hypothetical proteins:Cations and iron carrying compounds:Transport and binding proteins:Other:Regulatory functions:Purine ribonucleotide biosynthesis:Purines, pyrimidines, nucleosides, and nucleotides:Metabolism:Metabolism:Global:Folding Sorting and Degradation:Genetic Information Processing:Poorly characterized:Nucleotide Metabolism:Metabolism:Information storage and processing" 355 "Energy production and conversion:NTP pyrophosphohydrolases including oxidative damage repair enzymes:Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component, and related enzymes:Predicted permeases:D-alanyl-D-alanine carboxypeptidase:Acyl CoA:acetate/3-ketoacid CoA transferase, beta subunit:Uncharacterized protein involved in propionate catabolism:PEP phosphonomutase and related enzymes:ABC-type oligopeptide transport system, periplasmic component:Acetyl/propionyl-CoA carboxylase, alpha subunit:Competence protein ComGF:Amino acid transport and metabolism:Carbohydrate transport and metabolism:Lipid transport and metabolism:Replication, recombination and repair:Cell wall/membrane/envelope biogenesis:Glycolysis / Gluconeogenesis:Citrate cycle (TCA cycle):Fatty acid biosynthesis:Geraniol degradation:Pyruvate metabolism:Naphthalene degradation:Propanoate metabolism:Carbon fixation pathways in prokaryotes:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:ABC transporters:General function prediction only:prpB:prpD:pcaJ_scoB_fam:IV_pilin_GFxxxE:spore_V_AE:Intracellular trafficking, secretion, and vesicular transport:Metabolism:Cellular processes and signaling:Information storage and processing:Sporulation and germination:Cellular processes:Protein and peptide secretion and trafficking:Protein fate:Metabolism:Metabolism:Global:Membrane Transport:Environmental Information Processing:Xenobiotics Biodegradation and Metabolism:Metabolism of Terpenoids and Polyketides:Lipid Metabolism:Energy Metabolism:Poorly characterized:Carbohydrate Metabolism" 356 "Uncharacterized conserved protein:Fructose-2,6-bisphosphatase:Cell wall-associated hydrolases (invasion-associated proteins):Regulators of stationary/sporulation gene expression:ABC-type oligopeptide transport system, periplasmic component:Amino acid transport and metabolism:Carbohydrate transport and metabolism:Transcription:Cell wall/membrane/envelope biogenesis:ABC transporters:Function unknown:lp_hng_hel_AbrB:Information storage and processing:DNA interactions:Regulatory functions:Metabolism:Membrane Transport:Poorly characterized:Environmental Information Processing:Cellular processes and signaling" 357 "Energy production and conversion:F0F1-type ATP synthase, beta subunit:F0F1-type ATP synthase, alpha subunit:DNA-directed RNA polymerase, beta subunit/140 kD subunit:DNA-directed RNA polymerase, beta' subunit/160 kD subunit:Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), A subunit:Cysteinyl-tRNA synthetase:F0F1-type ATP synthase, gamma subunit:F0F1-type ATP synthase, epsilon subunit (mitochondrial delta subunit):rRNA methylases:Predicted phosphoesterase:RNase PH:ABC-type transport system involved in cytochrome c biogenesis, permease component:Heme/copper-type cytochrome/quinol oxidases, subunit 1:Serine acetyltransferase:Heme/copper-type cytochrome/quinol oxidases, subunit 2:Heme/copper-type cytochrome/quinol oxidase, subunit 3:Uncharacterized protein conserved in bacteria:Heme/copper-type cytochrome/quinol oxidase, subunit 4:Predicted RNA-binding protein containing a PIN domain:Uncharacterized protein conserved in bacteria:Amino acid transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:Replication, recombination and repair:Posttranslational modification, protein turnover, chaperones:Oxidative phosphorylation:Purine metabolism:Pyrimidine metabolism:Cysteine and methionine metabolism:Sulfur metabolism:Aminoacyl-tRNA biosynthesis:Metabolic pathways:Microbial metabolism in diverse environments:RNA polymerase:General function prediction only:Function unknown:yfcE:rRNA_methyl_3:cysS:atpA:atpD:gyrA:ATPsyn_F1gamma:cysE:ATP_synt_epsi:RNasePH:rpoB:rpoC_TIGR:CoxB:CtaD_CoxA:CoxD_Bacillus:cytochr_II_ccsB:M6dom_TIGR03296:Information storage and processing:Energy Metabolism:Nucleotide Metabolism:Amino Acid Metabolism:Genetic Information Processing:Transcription:Translation:Global:Metabolism:Energy metabolism:ATP-proton motive force interconversion:Electron transport:DNA metabolism:DNA replication, recombination, and repair:Transcription:DNA-dependent RNA polymerase:RNA processing:Protein synthesis:tRNA aminoacylation:tRNA and rRNA base modification:Protein fate:Protein modification and repair:Unknown function:Enzymes of unknown specificity:Amino acid biosynthesis:Serine family:Metabolism:Cellular processes and signaling:Metabolism:Poorly characterized" 358 "Energy production and conversion:Glutamate synthase domain 2:Fe-S oxidoreductase:Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II:ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component:Adenine deaminase:ADP-ribose pyrophosphatase:Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs:Lysine 2,3-aminomutase:Uncharacterized proteins, homologs of lactam utilization protein B:Uncharacterized conserved protein (some members contain a von Willebrand factor type A (vWA) domain):Carbon starvation protein, predicted membrane protein:Uncharacterized protein conserved in bacteria:Uncharacterized protein conserved in bacteria:Leucine-rich repeat (LRR) protein:L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily:Amino acid transport and metabolism:Nucleotide transport and metabolism:Lipid transport and metabolism:Transcription:Cell wall/membrane/envelope biogenesis:Inorganic ion transport and metabolism:Fatty acid metabolism:Purine metabolism:Alanine aspartate and glutamate metabolism:Lysine degradation:Nitrogen metabolism:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:ABC transporters:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:Function unknown:Signal transduction mechanisms:TIGR00238:LPXTG_anchor:oligo_HPY:YokU_near_AblA:Information storage and processing:Energy Metabolism:Lipid Metabolism:Nucleotide Metabolism:Amino Acid Metabolism:Environmental Information Processing:Membrane Transport:Global:Metabolism:Energy metabolism:Electron transport:Transport and binding proteins:Amino acids, peptides and amines:Unknown function:General:Cell envelope:Other:Metabolism:Cellular processes and signaling:Metabolism:Poorly characterized" 359 "Phosphoglycerate dehydrogenase and related dehydrogenases:Biotin-(acetyl-CoA carboxylase) ligase:Transcriptional regulator:Putative intracellular protease/amidase:2'-5' RNA ligase:Uncharacterized conserved protein:Phosphoserine aminotransferase:Site-specific recombinases, DNA invertase Pin homologs:Cytochrome P450:Predicted ring-cleavage extradiol dioxygenase:Uncharacterized conserved protein:Uncharacterized integral membrane protein:Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains:Arginine degradation protein (predicted deacylase):Amino acid transport and metabolism:Coenzyme transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:Replication, recombination and repair:Glycine serine and threonine metabolism:Bisphenol degradation:Polycyclic aromatic hydrocarbon degradation:Aminobenzoate degradation:Methane metabolism:Vitamin B6 metabolism:Biotin metabolism:Limonene and pinene degradation:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:Function unknown:Signal transduction mechanisms:birA_ligase:sensory_box:serC_1:B_ant_repeat:2_5_ligase:GNAT_ablB:Metabolism:Cellular processes and signaling:Information storage and processing:Serine family:Amino acid biosynthesis:Protein modification and repair:Protein fate:RNA processing:Transcription:Small molecule interactions:Regulatory functions:Metabolism:Metabolism:Global:Xenobiotics Biodegradation and Metabolism:Metabolism of Terpenoids and Polyketides:Metabolism of Cofactors and Vitamins:Amino Acid Metabolism:Poorly characterized:Energy Metabolism" 360 "Ribosomal protein S12:Ribosomal protein S2:Ribosomal protein L11:Ribosomal protein L1:Ribosomal protein L13:Ribosomal protein L27:Ribosomal protein L7/L12:Ribosomal protein L10:Ribosomal protein L21:Translation elongation factor Ts:Translation initiation factor 3 (IF-3):Ribosomal protein L35:Ribosomal protein S6:Single-stranded DNA-binding protein:Predicted ribosomal protein:Translation, ribosomal structure and biogenesis:Replication, recombination and repair:Ribosome:DNA replication:Mismatch repair:Homologous recombination:rpmI_bact:L21:L27:tsf:S6:infC:ssb:L12:rpsL_bact:rpsB_bact:rplM_bact:rplA_bact:L11_bact:Translation:Translation factors:Ribosomal proteins: synthesis and modification:Protein synthesis:DNA replication, recombination, and repair:DNA metabolism:Genetic Information Processing:Replication and Repair:Information storage and processing" 361 "Signal transduction histidine kinase:Amino acid transporters:Predicted ATP-dependent protease:GTPase:D-alanyl-D-alanine carboxypeptidase:Uncharacterized conserved protein:Lyzozyme M1 (1,4-beta-N-acetylmuramidase):Amino acid transport and metabolism:Cell wall/membrane/envelope biogenesis:Posttranslational modification, protein turnover, chaperones:Two-component system:General function prediction only:Function unknown:Signal transduction mechanisms:spore_lonB:Sporulation and germination:Cellular processes:Signal Transduction:Environmental Information Processing:Poorly characterized:Metabolism:Cellular processes and signaling" 362 "Isopropylmalate/homocitrate/citramalate synthases:Adenosylmethionine-8-amino-7-oxononanoate aminotransferase:2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway):Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases:Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases:Acyl CoA:acetate/3-ketoacid CoA transferase, alpha subunit:Transcriptional regulator/sugar kinase:Acyl CoA:acetate/3-ketoacid CoA transferase, beta subunit:3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases:4-hydroxyphenylpyruvate dioxygenase and related hemolysins:ABC-type oligopeptide transport system, periplasmic component:Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta):Amino acid transport and metabolism:Carbohydrate transport and metabolism:Coenzyme transport and metabolism:Lipid transport and metabolism:Transcription:Glycolysis / Gluconeogenesis:Galactose metabolism:Synthesis and degradation of ketone bodies:Ubiquinone and other terpenoid-quinone biosynthesis:Valine leucine and isoleucine degradation:Geraniol degradation:Arginine and proline metabolism:Tyrosine metabolism:Phenylalanine metabolism:Starch and sucrose metabolism:Amino sugar and nucleotide sugar metabolism:Streptomycin biosynthesis:Pyruvate metabolism:Naphthalene degradation:Glyoxylate and dicarboxylate metabolism:Propanoate metabolism:Butanoate metabolism:Methane metabolism:Carbon fixation pathways in prokaryotes:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:ABC transporters:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:LPXTG_anchor:4HPPD:DapE-ArgE:pcaJ_scoB_fam:pcaI_scoA_fam:GNAT_ablB:Biosynthesis of Other Secondary Metabolites:Metabolism of Terpenoids and Polyketides:Metabolism of Cofactors and Vitamins:Amino Acid Metabolism:Lipid Metabolism:Energy Metabolism:Metabolism:Carbohydrate Metabolism:Energy metabolism:Amino acids and amines:Protein fate:Degradation of proteins, peptides, and glycopeptides:Cell envelope:Other:Information storage and processing:Metabolism:Poorly characterized:Metabolism:Global:Membrane Transport:Environmental Information Processing:Xenobiotics Biodegradation and Metabolism" 363 "5'-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases:ABC-type multidrug transport system, ATPase component:Predicted metal-dependent membrane protease:Zn-dependent proteases:AraC-type DNA-binding domain-containing proteins:Uncharacterized conserved protein:Beta-glucosidase/6-phospho-beta-glucosidase/beta-galactosidase:Uncharacterized protein conserved in bacteria:L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily:Nucleotide transport and metabolism:Carbohydrate transport and metabolism:Transcription:Cell wall/membrane/envelope biogenesis:Purine metabolism:Pyrimidine metabolism:Cyanoamino acid metabolism:Starch and sucrose metabolism:Nicotinate and nicotinamide metabolism:Metabolic pathways:Biosynthesis of secondary metabolites:ABC transporters:General function prediction only:Function unknown:Defense mechanisms:Cellular processes and signaling:Carbohydrate Metabolism:Nucleotide Metabolism:Metabolism of Other Amino Acids:Metabolism of Cofactors and Vitamins:Environmental Information Processing:Membrane Transport:Global:Metabolism:Information storage and processing:Metabolism:Metabolism:Poorly characterized" 364 "Energy production and conversion:Predicted Co/Zn/Cd cation transporters:Short-chain dehydrogenases of various substrate specificities:Acetyltransferases:Transcriptional regulator:NADPH:quinone reductase and related Zn-dependent oxidoreductases:Predicted transcriptional regulators:N-acetylglutamate synthase and related acetyltransferases:Uncharacterized membrane protein:Transcriptional regulator:Predicted metal-dependent hydrolase:Transcriptional regulators:3-methyladenine DNA glycosylase:Uncharacterized stress protein (general stress protein 26):Uncharacterized protein conserved in bacteria:Amino acid transport and metabolism:Transcription:Replication, recombination and repair:Inorganic ion transport and metabolism:Tyrosine metabolism:Benzoate degradation:Naphthalene degradation:Aminobenzoate degradation:Ethylbenzene degradation:Limonene and pinene degradation:Microbial metabolism in diverse environments:Base excision repair:General function prediction only:Function unknown:3mg:CDF:DHAK_reg:Poorly characterized:Metabolism:Information storage and processing:Cations and iron carrying compounds:Transport and binding proteins:DNA replication, recombination, and repair:DNA metabolism:Metabolism:Metabolism:Global:Replication and Repair:Genetic Information Processing:Xenobiotics Biodegradation and Metabolism:Metabolism of Terpenoids and Polyketides:Amino Acid Metabolism" 365 "Cysteine synthase:Glucan phosphorylase:1,4-alpha-glucan branching enzyme:Glycogen synthase:Molybdopterin biosynthesis enzyme:Molybdopterin converting factor, large subunit:ADP-glucose pyrophosphorylase:Homoserine dehydrogenase:Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs:Transcriptional regulators:Molybdopterin-guanine dinucleotide biosynthesis protein:Nitrate/nitrite transporter:Predicted aminoglycoside phosphotransferase:Uncharacterized protein conserved in bacteria:Signal transduction histidine kinase regulating citrate/malate metabolism:Predicted acetyltransferase:Response regulator of citrate/malate metabolism:Amino acid transport and metabolism:Carbohydrate transport and metabolism:Coenzyme transport and metabolism:Transcription:Inorganic ion transport and metabolism:Glycine serine and threonine metabolism:Cysteine and methionine metabolism:Lysine biosynthesis:Selenocompound metabolism:Starch and sucrose metabolism:Amino sugar and nucleotide sugar metabolism:Sulfur metabolism:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:Two-component system:Sulfur relay system:General function prediction only:Function unknown:Signal transduction mechanisms:mobB:molyb_syn:cysKM:branching_enzym:glgC:P_ylase:glgA:Biosynthesis of cofactors, prosthetic groups, and carriers:Serine family:Amino acid biosynthesis:Biosynthesis and degradation of polysaccharides:Energy metabolism:Metabolism:Metabolism:Global:Signal Transduction:Environmental Information Processing:Folding Sorting and Degradation:Genetic Information Processing:Metabolism of Other Amino Acids:Amino Acid Metabolism:Energy Metabolism:Poorly characterized:Carbohydrate Metabolism:Metabolism:Cellular processes and signaling:Information storage and processing:Molybdopterin" 366 "Undecaprenyl pyrophosphate synthase:DNA-directed RNA polymerase, beta subunit/140 kD subunit:DNA-directed RNA polymerase, beta' subunit/160 kD subunit:Ribonuclease HII:Transcription elongation factor:Predicted GTPase:ABC-type cobalt transport system, permease component CbiQ and related transporters:Signal peptidase I:1-deoxy-D-xylulose 5-phosphate reductoisomerase:Uncharacterized protein conserved in bacteria:Ribosome-binding factor A:ABC-type cobalt transport system, ATPase component:Predicted GTPases:16S RNA G1207 methylase RsmC:Lipid transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:Replication, recombination and repair:Inorganic ion transport and metabolism:Purine metabolism:Pyrimidine metabolism:Terpenoid backbone biosynthesis:Metabolic pathways:Biosynthesis of secondary metabolites:ABC transporters:Two-component system:RNA polymerase:DNA replication:Protein export:General function prediction only:Function unknown:uppS:rbfA:small_GTP:Dxr:NusA:rpoB:sigpep_I_bact:rpoC_TIGR:GTPase_YlqF:Intracellular trafficking, secretion, and vesicular transport:Cell envelope:Nucleotide Metabolism:Metabolism of Terpenoids and Polyketides:Genetic Information Processing:Transcription:Folding Sorting and Degradation:Replication and Repair:Environmental Information Processing:Membrane Transport:Signal Transduction:Global:Metabolism:Transcription:DNA-dependent RNA polymerase:Transcription factors:RNA processing:Protein synthesis:Other:Protein fate:Protein and peptide secretion and trafficking:Unknown function:General:Biosynthesis of cofactors, prosthetic groups, and carriers:Other:Metabolism:Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides:Information storage and processing:Cellular processes and signaling:Metabolism:Poorly characterized" 367 "tRNA and rRNA cytosine-C5-methylases:Methionyl-tRNA formyltransferase:DNA mismatch repair enzyme (predicted ATPase):Predicted S-adenosylmethionine-dependent methyltransferase involved in bacterial cell division:Phosphopantothenoylcysteine synthetase/decarboxylase:Predicted GTPase:ATP-dependent exoDNAse (exonuclease V), alpha subunit - helicase superfamily I member:Phosphatidylglycerophosphate synthase:Single-stranded DNA-specific exonuclease:DNA polymerase I - 3'-5' exonuclease and polymerase domains:Predicted Fe-S-cluster redox enzyme:Predicted nucleotide-utilizing enzyme related to molybdopterin-biosynthesis enzyme MoeA:Cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes:Predicted GTPases:Uncharacterized protein conserved in bacteria:DNA polymerase IV (family X):Predicted membrane protein:Amino acid transport and metabolism:Coenzyme transport and metabolism:Lipid transport and metabolism:Translation, ribosomal structure and biogenesis:Replication, recombination and repair:Cell wall/membrane/envelope biogenesis:Purine metabolism:Pyrimidine metabolism:Glycerophospholipid metabolism:One carbon pool by folate:Thiamine metabolism:Pantothenate and CoA biosynthesis:Aminoacyl-tRNA biosynthesis:Metabolic pathways:DNA replication:Base excision repair:Nucleotide excision repair:Mismatch repair:Homologous recombination:Sulfur relay system:General function prediction only:Function unknown:TIGR00048:gidB:molyb_syn:small_GTP:fmt:coaBC_dfp:pgsA:rsmB:mutl:pola:recJ:recD_rel:spore_YtaF:GTPase_YqeH:Biosynthesis of cofactors, prosthetic groups, and carriers:Lipid Metabolism:Nucleotide Metabolism:Metabolism of Cofactors and Vitamins:Genetic Information Processing:Translation:Folding Sorting and Degradation:Replication and Repair:Global:Metabolism:Fatty acid and phospholipid metabolism:Biosynthesis:DNA metabolism:DNA replication, recombination, and repair:Protein synthesis:Other:tRNA aminoacylation:tRNA and rRNA base modification:Cellular processes:Sporulation and germination:Unknown function:Enzymes of unknown specificity:General:Metabolism:Pantothenate and coenzyme A:Information storage and processing:Cellular processes and signaling:Metabolism:Poorly characterized" 368 "Zn-dependent hydrolases, including glyoxylases:Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily):Predicted transcriptional regulators:GTP cyclohydrolase II:Putative copper export protein:Predicted transcriptional regulator:Pyrimidine reductase, riboflavin biosynthesis:Predicted dithiol-disulfide isomerase involved in polyketide biosynthesis:Putative NADH-flavin reductase:Predicted protein-disulfide isomerase:Predicted oxidoreductase related to nitroreductase:Ketosteroid isomerase-related protein:Uncharacterized protein conserved in bacteria:Uncharacterized protein conserved in bacteria:Coenzyme transport and metabolism:Transcription:Posttranslational modification, protein turnover, chaperones:Inorganic ion transport and metabolism:Riboflavin metabolism:Metabolic pathways:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:Function unknown:ribD_Cterm:Poorly characterized:Metabolism:Cellular processes and signaling:Information storage and processing:Metabolism:Global:Metabolism of Cofactors and Vitamins:Metabolism" 369 "Na+-driven multidrug efflux pump:Transcriptional regulator:DNA repair photolyase:Predicted transcriptional regulators:Membrane transporters of cations and cationic drugs:Predicted membrane protein:Uncharacterized conserved protein:Predicted membrane protein:Uncharacterized protein conserved in bacteria:Transcription:Replication, recombination and repair:Inorganic ion transport and metabolism:Function unknown:matE:photo_TT_lyase:Defense mechanisms:Metabolism:Cellular processes and signaling:Information storage and processing:Sporulation and germination:Cellular processes:Other:Transport and binding proteins:Poorly characterized" 370 "Acetyltransferase (isoleucine patch superfamily):ATPases involved in chromosome partitioning:NTP pyrophosphohydrolases including oxidative damage repair enzymes:Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain:Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs:Aspartate racemase:Predicted acyltransferases:Uncharacterized protein conserved in bacteria:Predicted membrane protein:Sugar transferases involved in lipopolysaccharide synthesis:Membrane protein involved in the export of O-antigen and teichoic acid:Capsular polysaccharide biosynthesis protein:Uncharacterized conserved protein:Cell cycle control, cell division, chromosome partitioning:Amino acid transport and metabolism:Lipid transport and metabolism:Transcription:Replication, recombination and repair:Cell wall/membrane/envelope biogenesis:Alanine aspartate and glutamate metabolism:General function prediction only:Function unknown:Signal transduction mechanisms:asp_race:Amino Acid Metabolism:Poorly characterized:Metabolism:Cellular processes and signaling:Information storage and processing:Amino acids and amines:Energy metabolism:Metabolism" 371 "Energy production and conversion:Pseudouridine synthase:Aspartate-semialdehyde dehydrogenase:5,10-methylene-tetrahydrofolate dehydrogenase/Methenyl tetrahydrofolate cyclohydrolase:FAD synthase:Cytidine deaminase:Dihydrodipicolinate synthase/N-acetylneuraminate lyase:FOG: CBS domain:Aspartokinases:Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, alpha subunit:ABC-type Mn2+/Zn2+ transport systems, permease components:GTPase:Uncharacterized protein conserved in bacteria:Predicted kinase related to dihydroxyacetone kinase:DNA segregation ATPase FtsK/SpoIIIE and related proteins:Uncharacterized protein conserved in bacteria:Uncharacterized conserved small protein:Cell cycle control, cell division, chromosome partitioning:Amino acid transport and metabolism:Nucleotide transport and metabolism:Coenzyme transport and metabolism:Translation, ribosomal structure and biogenesis:Cell wall/membrane/envelope biogenesis:Inorganic ion transport and metabolism:Citrate cycle (TCA cycle):Pyrimidine metabolism:Glycine serine and threonine metabolism:Cysteine and methionine metabolism:Lysine biosynthesis:One carbon pool by folate:Carbon fixation pathways in prokaryotes:Riboflavin metabolism:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:ABC transporters:General function prediction only:Function unknown:ribF:small_GTP:TruB:asp_kin_monofn:dapA:asd_B:cyt_deam_tetra:YloV:OAFO_sf:Protein synthesis:Salvage of nucleosides and nucleotides:Purines, pyrimidines, nucleosides, and nucleotides:Metabolism:Global:Metabolism:Membrane Transport:Environmental Information Processing:Metabolism of Cofactors and Vitamins:Amino Acid Metabolism:Nucleotide Metabolism:Energy Metabolism:General:Carbohydrate Metabolism:Amino acid biosynthesis:Aspartate family:Biosynthesis of cofactors, prosthetic groups, and carriers:Riboflavin, FMN, and FAD:Information storage and processing:Cellular processes and signaling:Metabolism:Poorly characterized:Unknown function:tRNA and rRNA base modification" 372 "Recombinational DNA repair protein (RecF pathway):6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase:UDP-N-acetylglucosamine 2-epimerase:Uncharacterized conserved protein:Biotin carboxylase:K+ transport systems, NAD-binding component:Preprotein translocase subunit YidC:Uncharacterized protein conserved in bacteria:Predicted transcriptional regulators containing the CopG/Arc/MetJ DNA-binding domain and a metal-binding domain:Transcription termination factor:UDP-glucose pyrophosphorylase:Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily:Predicted HD superfamily hydrolase:Predicted transcriptional regulator:Growth inhibitor:Putative primosome component and related proteins:Carbohydrate transport and metabolism:Lipid transport and metabolism:Transcription:Replication, recombination and repair:Cell wall/membrane/envelope biogenesis:Inorganic ion transport and metabolism:Pentose and glucuronate interconversions:Galactose metabolism:Fatty acid biosynthesis:Starch and sucrose metabolism:Amino sugar and nucleotide sugar metabolism:Pyruvate metabolism:Propanoate metabolism:Carbon fixation pathways in prokaryotes:Metabolic pathways:Biosynthesis of secondary metabolites:RNA degradation:Protein export:Bacterial secretion system:Homologous recombination:General function prediction only:Function unknown:Signal transduction mechanisms:DNA_YbaB_EbfC:wecB:HDIG:nagB:accC:recR:rho:galU:DnaD_dom:CofD_related:yidC_oxa1_cterm:Intracellular trafficking, secretion, and vesicular transport:Cell envelope:Carbohydrate Metabolism:Energy Metabolism:Lipid Metabolism:Genetic Information Processing:Folding Sorting and Degradation:Replication and Repair:Environmental Information Processing:Membrane Transport:Global:Metabolism:Central intermediary metabolism:Amino sugars:Fatty acid and phospholipid metabolism:Biosynthesis:DNA metabolism:DNA replication, recombination, and repair:Transcription:Transcription factors:Protein fate:Protein and peptide secretion and trafficking:Mobile and extrachromosomal element functions:Prophage functions:Hypothetical proteins:Conserved:Unknown function:General:Metabolism:Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides:Information storage and processing:Cellular processes and signaling:Metabolism:Poorly characterized" 373 "Energy production and conversion:Ribose 5-phosphate isomerase:Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2:Uridylate kinase:FOG: Ankyrin repeat:ABC-type dipeptide/oligopeptide/nickel transport systems, permease components:DhnA-type fructose-1,6-bisphosphate aldolase and related enzymes:Uncharacterized conserved protein:Ni,Fe-hydrogenase III component G:Lyzozyme M1 (1,4-beta-N-acetylmuramidase):Amino acid transport and metabolism:Nucleotide transport and metabolism:Carbohydrate transport and metabolism:Coenzyme transport and metabolism:Cell wall/membrane/envelope biogenesis:Inorganic ion transport and metabolism:Pentose phosphate pathway:Oxidative phosphorylation:Pyrimidine metabolism:Benzoate degradation:Bisphenol degradation:Naphthalene degradation:Butanoate metabolism:Limonene and pinene degradation:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:ABC transporters:General function prediction only:Function unknown:rpiA:LPXTG_anchor:NuoC_fam:pyrH_bact:spore_YlmC_YmxH:Other:Carbohydrate Metabolism:Energy Metabolism:Nucleotide Metabolism:Metabolism of Terpenoids and Polyketides:Xenobiotics Biodegradation and Metabolism:Environmental Information Processing:Membrane Transport:Global:Metabolism:Energy metabolism:Electron transport:Pentose phosphate pathway:Purines, pyrimidines, nucleosides, and nucleotides:Nucleotide and nucleoside interconversions:Cellular processes:Sporulation and germination:Cell envelope:Metabolism:Cellular processes and signaling:Metabolism:Poorly characterized" 374 "Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), B subunit:Predicted enzyme with a TIM-barrel fold:Predicted S-adenosylmethionine-dependent methyltransferase involved in bacterial cell division:Predicted GTPase:NTP pyrophosphohydrolases including oxidative damage repair enzymes:Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain:Actin-like ATPase involved in cell division:Septum formation inhibitor:Uncharacterized protein conserved in bacteria:Predicted P-loop-containing kinase:Uncharacterized protein conserved in bacteria:Phosphotransferase system, HPr-related proteins:DNA polymerase III, gamma/tau subunits:Septum formation inhibitor-activating ATPase:Signal transduction histidine kinase regulating citrate/malate metabolism:Uncharacterized protein conserved in bacteria:Cell cycle control, cell division, chromosome partitioning:Carbohydrate transport and metabolism:Transcription:Replication, recombination and repair:Cell wall/membrane/envelope biogenesis:Purine metabolism:Pyrimidine metabolism:Metabolic pathways:Two-component system:DNA replication:Mismatch repair:Homologous recombination:General function prediction only:Function unknown:Signal transduction mechanisms:TIGR00044:gidB:sensory_box:small_GTP:MG103:holB:PTS_HPr_family:gyrB:ftsA:minC:minD_bact:spore_yabQ:Information storage and processing:Cellular processes and signaling:Metabolism:Poorly characterized:tRNA and rRNA base modification:Protein synthesis:DNA replication, recombination, and repair:DNA metabolism:Small molecule interactions:Regulatory functions:Metabolism:Metabolism:Global:Signal Transduction:Environmental Information Processing:Replication and Repair:Genetic Information Processing:Cellular processes:Nucleotide Metabolism:Cell division:Sporulation and germination:Hypothetical proteins:Conserved:Unknown function:Enzymes of unknown specificity:General:Signal transduction:PTS" 375 "Lactoylglutathione lyase and related lyases:Predicted epimerase, PhzC/PhzF homolog:Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily):Signal transduction histidine kinase:Membrane carboxypeptidase (penicillin-binding protein):Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain:ABC-type multidrug transport system, ATPase and permease components:Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs:Dipeptidyl aminopeptidases/acylaminoacyl-peptidases:Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains:Amino acid transport and metabolism:Transcription:Cell wall/membrane/envelope biogenesis:Peptidoglycan biosynthesis:Metabolic pathways:General function prediction only:Signal transduction mechanisms:PhzF_family:PBP_1a_fam:Defense mechanisms:Cellular processes:Metabolism:Global:Information storage and processing:Glycan Biosynthesis and Metabolism:Cellular processes and signaling:Metabolism:Poorly characterized:Metabolism:Biosynthesis and degradation of murein sacculus and peptidoglycan:Cell envelope:Toxin production and resistance" 376 "NTP pyrophosphohydrolases including oxidative damage repair enzymes:UDP-N-acetyl-D-mannosaminuronate dehydrogenase:N-acetylmuramoyl-L-alanine amidase:ABC-type multidrug transport system, ATPase component:Putative effector of murein hydrolase:Phage-related protein:Uncharacterized protein conserved in bacteria:Replication, recombination and repair:Cell wall/membrane/envelope biogenesis:Fructose and mannose metabolism:Bisphenol degradation:Chloroalkane and chloroalkene degradation:Butanoate metabolism:Metabolic pathways:Microbial metabolism in diverse environments:ABC transporters:General function prediction only:Function unknown:yxeA_fam:NDP-sugDHase:Defense mechanisms:Hypothetical proteins:Carbohydrate Metabolism:Xenobiotics Biodegradation and Metabolism:Environmental Information Processing:Membrane Transport:Global:Metabolism:Metabolism:Conserved:Information storage and processing:Cellular processes and signaling:Poorly characterized" 377 "Pyrroline-5-carboxylate reductase:Homoserine dehydrogenase:Zn-dependent hydrolases, including glyoxylases:NTP pyrophosphohydrolases including oxidative damage repair enzymes:Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily):Serine/threonine protein phosphatase:Predicted xylanase/chitin deacetylase:Periplasmic protease:Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs:Uncharacterized vancomycin resistance protein:Lysophospholipase L1 and related esterases:Predicted membrane protein:Amino acid transport and metabolism:Carbohydrate transport and metabolism:Transcription:Replication, recombination and repair:Cell wall/membrane/envelope biogenesis:Glycine serine and threonine metabolism:Cysteine and methionine metabolism:Lysine biosynthesis:Arginine and proline metabolism:Benzoate degradation:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:General function prediction only:Function unknown:Signal transduction mechanisms:proC:prc:Defense mechanisms:Metabolism:Metabolism:Global:Xenobiotics Biodegradation and Metabolism:Poorly characterized:Amino Acid Metabolism:Metabolism:Cellular processes and signaling:Information storage and processing:Glutamate family:Amino acid biosynthesis:Protein modification and repair:Protein fate" 378 "Energy production and conversion:MoxR-like ATPases:ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components:Monoamine oxidase:Cytochrome bd-type quinol oxidase, subunit 1:Uncharacterized conserved protein:Amino acid transport and metabolism:Inorganic ion transport and metabolism:Oxidative phosphorylation:Glycine serine and threonine metabolism:Arginine and proline metabolism:Histidine metabolism:Tyrosine metabolism:Phenylalanine metabolism:Tryptophan metabolism:Metabolic pathways:Biosynthesis of secondary metabolites:ABC transporters:General function prediction only:Function unknown:2A0309:spore_III_AE:spore_III_D:spore_YlmC_YmxH:Sporulation and germination:Metabolism:Poorly characterized:Transport and binding proteins:Metabolism:Metabolism:Global:Membrane Transport:Environmental Information Processing:Amino Acid Metabolism:Amino acids, peptides and amines:Energy Metabolism:Cellular processes" 379 "Alanyl-tRNA synthetase:Aspartyl/asparaginyl-tRNA synthetases:Isoleucyl-tRNA synthetase:Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase:Chorismate synthase:Homoserine kinase:Histidyl-tRNA synthetase:Seryl-tRNA synthetase:Aspartyl-tRNA synthetase:Glutamate 5-kinase:Prephenate dehydrogenase:Threonyl-tRNA synthetase:Prolyl-tRNA synthetase:Homoserine dehydrogenase:Leucyl-tRNA synthetase:Threonine synthase:Valyl-tRNA synthetase:Amino acid transporters:Aldo/keto reductases, related to diketogulonate reductase:Branched-chain amino acid permeases:Lysyl-tRNA synthetase (class I):Asparagine synthetase A:3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase:Amino acid transport and metabolism:Translation, ribosomal structure and biogenesis:Alanine aspartate and glutamate metabolism:Glycine serine and threonine metabolism:Cysteine and methionine metabolism:Valine leucine and isoleucine biosynthesis:Lysine biosynthesis:Arginine and proline metabolism:Histidine metabolism:Tyrosine metabolism:Phenylalanine metabolism:Phenylalanine tyrosine and tryptophan biosynthesis:Novobiocin biosynthesis:Cyanoamino acid metabolism:Vitamin B6 metabolism:Nitrogen metabolism:Aminoacyl-tRNA biosynthesis:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:General function prediction only:aroC:thrB:thrC:alaS:ileS:leuS_bact:proS_fam_I:serS:thrS:valS:hisS:aspS_arch:aspS_bact:lysS_arch:asnA:livcs:proB:hisC:DAHP_synth_Bsub:Glutamate family:Aspartate family:Aromatic amino acid family:Amino acid biosynthesis:Amino acids, peptides and amines:Transport and binding proteins:tRNA aminoacylation:Protein synthesis:Metabolism:Metabolism:Global:Translation:Genetic Information Processing:Biosynthesis of Other Secondary Metabolites:Metabolism of Cofactors and Vitamins:Metabolism of Other Amino Acids:Amino Acid Metabolism:Poorly characterized:Energy Metabolism:Metabolism:Information storage and processing:Histidine family" 380 "Energy production and conversion:Methionine aminopeptidase:Predicted rRNA methylase (SpoU class):UDP-N-acetylglucosamine 2-epimerase:cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases:ABC-type molybdate transport system, periplasmic component:Predicted transcriptional regulators:Arginine repressor:Transcriptional regulators:Heme/copper-type cytochrome/quinol oxidase, subunit 4:Predicted HD-superfamily hydrolase:Uncharacterized conserved protein:ABC-type molybdate transport system, permease component:Response regulator of citrate/malate metabolism:Translation, ribosomal structure and biogenesis:Transcription:Cell wall/membrane/envelope biogenesis:Inorganic ion transport and metabolism:Oxidative phosphorylation:Amino sugar and nucleotide sugar metabolism:Metabolic pathways:ABC transporters:Two-component system:General function prediction only:Function unknown:Signal transduction mechanisms:rRNA_methyl_2:wecB:met_pdase_I:modA:argR_whole:modB_ABC:spore_0_A:QoxD:DivI1A_domain:Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides:Information storage and processing:Cellular processes and signaling:Metabolism:Poorly characterized:tRNA and rRNA base modification:Protein synthesis:DNA interactions:Regulatory functions:Electron transport:Energy metabolism:Metabolism:Metabolism:Global:Signal Transduction:Membrane Transport:Environmental Information Processing:Energy Metabolism:Protein fate:Carbohydrate Metabolism:Protein modification and repair:Transport and binding proteins:Anions:Cellular processes:Sporulation and germination:Cell envelope" 381 "Ribonuclease HI:Membrane protease subunits, stomatin/prohibitin homologs:NAD-dependent protein deacetylases, SIR2 family:Transcriptional regulators:Membrane protein implicated in regulation of membrane protease activity:Uncharacterized conserved protein:Putative NADPH-quinone reductase (modulator of drug activity B):Predicted permeases:Genetic competence transcription factor:Predicted permease, DMT superfamily:Transcription:Replication, recombination and repair:Posttranslational modification, protein turnover, chaperones:Histidine metabolism:Tyrosine metabolism:Selenocompound metabolism:Polycyclic aromatic hydrocarbon degradation:Microbial metabolism in diverse environments:DNA replication:General function prediction only:Function unknown:TIGR00266:Intracellular trafficking, secretion, and vesicular transport:Cellular processes and signaling:Amino Acid Metabolism:Metabolism of Other Amino Acids:Xenobiotics Biodegradation and Metabolism:Genetic Information Processing:Replication and Repair:Global:Metabolism:Hypothetical proteins:Conserved:Information storage and processing:Metabolism:Poorly characterized" 382 "Arginase/agmatinase/formimionoglutamate hydrolase, arginase family:L-asparaginase/archaeal Glu-tRNAGln amidotransferase subunit D:NTP pyrophosphohydrolases including oxidative damage repair enzymes:Predicted xylanase/chitin deacetylase:UDP-N-acetylmuramoylalanine-D-glutamate ligase:Branched-chain amino acid permeases:Predicted membrane GTPase involved in stress response:Protoporphyrinogen oxidase:Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily:Protein-disulfide isomerase:Uncharacterized bacitracin resistance protein:Nucleoside permease:Protein tyrosine/serine phosphatase:Uncharacterized Zn-ribbon-containing protein involved in phosphonate metabolism:Amino acid transport and metabolism:Nucleotide transport and metabolism:Carbohydrate transport and metabolism:Coenzyme transport and metabolism:Translation, ribosomal structure and biogenesis:Replication, recombination and repair:Cell wall/membrane/envelope biogenesis:Posttranslational modification, protein turnover, chaperones:Inorganic ion transport and metabolism:Alanine aspartate and glutamate metabolism:Arginine and proline metabolism:Phosphonate and phosphinate metabolism:Cyanoamino acid metabolism:D-Glutamine and D-glutamate metabolism:Peptidoglycan biosynthesis:Porphyrin and chlorophyll metabolism:Nitrogen metabolism:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:General function prediction only:Signal transduction mechanisms:small_GTP:proto_IX_ox:phnA:undec_PP_bacA:livcs:murD:agmatinase:Defense mechanisms:Metabolism:Metabolism:Global:Metabolism of Cofactors and Vitamins:Glycan Biosynthesis and Metabolism:Metabolism of Other Amino Acids:Amino Acid Metabolism:Cell envelope:Energy Metabolism:Biosynthesis and degradation of murein sacculus and peptidoglycan:Information storage and processing:Cellular processes and signaling:Metabolism:Poorly characterized:Heme, porphyrin, and cobalamin:Biosynthesis of cofactors, prosthetic groups, and carriers:General:Unknown function:Amino acids, peptides and amines:Transport and binding proteins" 383 "Ribosomal protein S2:Ribosomal protein L11:Ribosomal protein L27:Ribosomal protein L10:Ribosomal protein L31:Ribosomal protein L21:Ribosomal protein S6:Ribosomal protein S4 and related proteins:Single-stranded DNA-binding protein:Predicted ribosomal protein:Translation, ribosomal structure and biogenesis:Replication, recombination and repair:Ribosome:DNA replication:Mismatch repair:Homologous recombination:S21p:L21:L27:L31:S6:ssb:rpsB_bact:rpsD_bact:L11_bact:DNA metabolism:Translation:Replication and Repair:Genetic Information Processing:DNA replication, recombination, and repair:Protein synthesis:Ribosomal proteins: synthesis and modification:Information storage and processing" 384 "Acetyl-CoA acetyltransferase:Amino acid transporters:N-acetylmuramoyl-L-alanine amidase:Beta-lactamase class C and other penicillin binding proteins:Inosine-uridine nucleoside N-ribohydrolase:H+/gluconate symporter and related permeases:Amino acid transport and metabolism:Nucleotide transport and metabolism:Carbohydrate transport and metabolism:Lipid transport and metabolism:Cell wall/membrane/envelope biogenesis:Fatty acid metabolism:Synthesis and degradation of ketone bodies:Purine metabolism:Valine leucine and isoleucine degradation:Lysine degradation:Benzoate degradation:Tryptophan metabolism:Pyruvate metabolism:Glyoxylate and dicarboxylate metabolism:Propanoate metabolism:Butanoate metabolism:Carbon fixation pathways in prokaryotes:Nicotinate and nicotinamide metabolism:Terpenoid backbone biosynthesis:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:Two-component system:gntP:2A0309:AcCoA-C-Actrans:Defense mechanisms:Fatty acid and phospholipid metabolism:Other:Transport and binding proteins:Amino acids, peptides and amines:Carbohydrates, organic alcohols, and acids:Cellular processes and signaling:Metabolism:Global:Signal Transduction:Environmental Information Processing:Xenobiotics Biodegradation and Metabolism:Metabolism of Terpenoids and Polyketides:Metabolism of Cofactors and Vitamins:Amino Acid Metabolism:Nucleotide Metabolism:Lipid Metabolism:Energy Metabolism:Metabolism:Carbohydrate Metabolism:Metabolism" 385 "Energy production and conversion:Signal transduction histidine kinase:Ribose 5-phosphate isomerase RpiB:NADH dehydrogenase, FAD-containing subunit:Transcriptional regulator:Cellulase M and related proteins:Metal-dependent amidase/aminoacylase/carboxypeptidase:Serine kinase of the HPr protein, regulates carbohydrate metabolism:Transcriptional regulators:Predicted transcriptional regulators:Uncharacterized conserved protein:N-acetylglucosamine-6-phosphate deacetylase:Deoxycytidylate deaminase:Sugar phosphate permease:Uncharacterized conserved protein:Predicted membrane protein:Nucleotide transport and metabolism:Carbohydrate transport and metabolism:Transcription:Pentose phosphate pathway:Oxidative phosphorylation:Pyrimidine metabolism:Lysine biosynthesis:Amino sugar and nucleotide sugar metabolism:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:General function prediction only:Function unknown:Signal transduction mechanisms:nagA:IMPACT_YIGZ:hpr-ser:rpiB_lacA_lacB:B_ant_repeat:amidohydrolases:ComEB:caa3_CtaG:Central intermediary metabolism:Metabolism:Metabolism:Global:Amino Acid Metabolism:Nucleotide Metabolism:Energy Metabolism:Unknown function:Carbohydrate Metabolism:General:Signal transduction:PTS:Information storage and processing:Cellular processes and signaling:Metabolism:Poorly characterized:Degradation of proteins, peptides, and glycopeptides:Protein fate:Amino sugars" 386 "Cation transport ATPase:Phosphatidylserine synthase:Uncharacterized membrane protein:Transcriptional regulator:DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog:Beta-lactamase class C and other penicillin binding proteins:Predicted transcriptional regulators:Transcriptional regulators:Leucyl aminopeptidase (aminopeptidase T):Predicted dienelactone hydrolase:Glycopeptide antibiotics resistance protein:Amino acid transport and metabolism:Lipid transport and metabolism:Transcription:Inorganic ion transport and metabolism:Glycine serine and threonine metabolism:Tyrosine metabolism:Benzoate degradation:Glycerophospholipid metabolism:Naphthalene degradation:Aminobenzoate degradation:Ethylbenzene degradation:Limonene and pinene degradation:Metabolic pathways:Microbial metabolism in diverse environments:RNA polymerase:General function prediction only:Function unknown:pssA:efflux_EmrB:ATPase_P-type:sigma70-ECF:Defense mechanisms:Poorly characterized:Lipid Metabolism:Amino Acid Metabolism:Metabolism of Terpenoids and Polyketides:Xenobiotics Biodegradation and Metabolism:Genetic Information Processing:Transcription:Global:Metabolism:Fatty acid and phospholipid metabolism:Biosynthesis:Transport and binding proteins:Other:Information storage and processing:Cellular processes and signaling:Metabolism:Metabolism" 387 "Energy production and conversion:Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases:Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II:Glycosidases:Sugar kinases, ribokinase family:Alanine dehydrogenase:Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific:Phosphotransferase system, fructose-specific IIC component:Phosphotransferase system cellobiose-specific component IIB:Phosphotransferase system cellobiose-specific component IIA:Phosphotransferase system cellobiose-specific component IIC:Transcriptional regulators:L-lactate permease:Beta-fructosidases (levanase/invertase):Selenocysteine synthase [seryl-tRNASer selenium transferase]:Predicted sugar phosphate isomerase:Metal-dependent hydrolase:Uncharacterized conserved protein:Predicted amidohydrolase:ABC-type oligopeptide transport system, periplasmic component:Predicted kinase:Amino acid transport and metabolism:Carbohydrate transport and metabolism:Lipid transport and metabolism:Transcription:Glycolysis / Gluconeogenesis:Pentose phosphate pathway:Pentose and glucuronate interconversions:Fructose and mannose metabolism:Galactose metabolism:Fatty acid metabolism:Pyrimidine metabolism:Alanine aspartate and glutamate metabolism:Cysteine and methionine metabolism:Taurine and hypotaurine metabolism:Selenocompound metabolism:Starch and sucrose metabolism:Amino sugar and nucleotide sugar metabolism:Aminoacyl-tRNA biosynthesis:Metabolic pathways:Microbial metabolism in diverse environments:ABC transporters:Phosphotransferase system (PTS):Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:Function unknown:TIGR00274:cello_pts_IIC:lacE:alaDH:lctP:EIIB_glc:FRU:scrB_fam:selA_rel:MTRK:trehalose_treC:EF_0839:EF_0837:PTS:Carbohydrate Metabolism:Lipid Metabolism:Nucleotide Metabolism:Amino Acid Metabolism:Metabolism of Other Amino Acids:Genetic Information Processing:Translation:Environmental Information Processing:Membrane Transport:Global:Metabolism:Energy metabolism:Amino acids and amines:Biosynthesis and degradation of polysaccharides:Transport and binding proteins:Carbohydrates, organic alcohols, and acids:Hypothetical proteins:Conserved:Unknown function:Enzymes of unknown specificity:Signal transduction:Metabolism:Cell envelope:Biosynthesis and degradation of murein sacculus and peptidoglycan:Information storage and processing:Metabolism:Poorly characterized" 388 "Predicted methyltransferases:Transcriptional regulator:Na+/proline symporter:Spermidine/putrescine-binding periplasmic protein:Cell division protein FtsI/penicillin-binding protein 2:ABC-type multidrug transport system, ATPase component:Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1:Na+/phosphate symporter:L-serine deaminase:D-alanyl-D-alanine carboxypeptidase:Predicted membrane protein:Amino acid transport and metabolism:Coenzyme transport and metabolism:Transcription:Cell wall/membrane/envelope biogenesis:Inorganic ion transport and metabolism:Glycine serine and threonine metabolism:Cysteine and methionine metabolism:Peptidoglycan biosynthesis:Metabolic pathways:Biosynthesis of secondary metabolites:ABC transporters:General function prediction only:Function unknown:TIGR00096:NaPi_cotrn_rel:sda_alpha:sda_beta:sss:Defense mechanisms:Enzymes of unknown specificity:Amino Acid Metabolism:Glycan Biosynthesis and Metabolism:Environmental Information Processing:Membrane Transport:Global:Metabolism:Energy metabolism:Glycolysis/gluconeogenesis:Transport and binding proteins:Cations and iron carrying compounds:Unknown function:Metabolism:Information storage and processing:Cellular processes and signaling:Metabolism:Poorly characterized" 389 "Energy production and conversion:ABC-type Fe3+-hydroxamate transport system, periplasmic component:Predicted permease:Nitroreductase:Predicted transcriptional regulators:Gamma-aminobutyrate permease and related permeases:ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components:Alcohol dehydrogenase, class IV:Predicted transcriptional regulator with C-terminal CBS domains:Amino acid transport and metabolism:Coenzyme transport and metabolism:Transcription:Inorganic ion transport and metabolism:Glycerolipid metabolism:ABC transporters:General function prediction only:Environmental Information Processing:Lipid Metabolism:Metabolism:Poorly characterized:Metabolism:Information storage and processing:Membrane Transport" 390 "Fructose-2,6-bisphosphatase:Transcriptional regulator:Holliday junction resolvasome, DNA-binding subunit:Ribonuclease HIII:Recombinational DNA repair ATPase (RecF pathway):Uncharacterized membrane protein, required for colicin V production:DNA segregation ATPase FtsK/SpoIIIE and related proteins:Predicted transcriptional regulators:DNA polymerase IV (family X):Uncharacterized conserved protein:Uncharacterized protein conserved in bacteria:Membrane-bound metallopeptidase:Cell cycle control, cell division, chromosome partitioning:Carbohydrate transport and metabolism:Transcription:Replication, recombination and repair:Glycolysis / Gluconeogenesis:Methane metabolism:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:DNA replication:Homologous recombination:General function prediction only:Function unknown:ruvA:recf:rnhC:YaaA_near_RecF:Metabolism:Cellular processes and signaling:Information storage and processing:DNA replication, recombination, and repair:DNA metabolism:Metabolism:Metabolism:Global:Replication and Repair:Genetic Information Processing:Energy Metabolism:Poorly characterized:Carbohydrate Metabolism" 391 "Ribosomal protein L11:Uncharacterized conserved protein:Putative glucose uptake permease:Carbohydrate transport and metabolism:Translation, ribosomal structure and biogenesis:Ribosome:Function unknown:RhaT:B_ant_repeat:L11_bact:phge_HK97_gp10:Mobile and extrachromosomal element functions:Translation:Protein synthesis:Ribosomal proteins: synthesis and modification:Transport and binding proteins:Carbohydrates, organic alcohols, and acids:Genetic Information Processing:Prophage functions:Information storage and processing:Metabolism:Poorly characterized" 392 "Fructose-2,6-bisphosphatase:Acetyltransferases:NTP pyrophosphohydrolases including oxidative damage repair enzymes:Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily):Predicted HD superfamily hydrolase involved in NAD metabolism:Uncharacterized conserved protein:Uncharacterized membrane protein, possible Na+ channel or pump:Allophanate hydrolase subunit 2:Amino acid transport and metabolism:Carbohydrate transport and metabolism:Coenzyme transport and metabolism:Replication, recombination and repair:Glycolysis / Gluconeogenesis:Arginine and proline metabolism:Methane metabolism:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:General function prediction only:Function unknown:HDIG:urea_amlyse_rel:Information storage and processing:Carbohydrate Metabolism:Energy Metabolism:Amino Acid Metabolism:Global:Metabolism:Unknown function:General:Metabolism:Metabolism:Poorly characterized" 393 "Energy production and conversion:Transcriptional regulator:NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit:Non-ribosomal peptide synthetase modules and related proteins:Formate hydrogenlyase subunit 6/NADH:ubiquinone oxidoreductase 23 kD subunit (chain I):ABC-type Fe3+ transport system, permease component:Phytoene dehydrogenase and related proteins:Predicted phosphohydrolases:Zinc metalloprotease (elastase):Amino acid transport and metabolism:Transcription:Inorganic ion transport and metabolism:Oxidative phosphorylation:Metabolic pathways:ABC transporters:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:NRPS-para261:NuoI:NDH_I_L:spore_dpaB:spore_yabG:Sporulation and germination:Energy Metabolism:Environmental Information Processing:Membrane Transport:Global:Metabolism:Energy metabolism:Electron transport:Cellular processes:Metabolism:Information storage and processing:Metabolism:Poorly characterized" 394 "Energy production and conversion:Dimethyladenosine transferase (rRNA methylation):5-formyltetrahydrofolate cyclo-ligase:Integral membrane protein possibly involved in chromosome condensation:2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase:Uncharacterized conserved protein:Metal-dependent proteases with possible chaperone activity:Predicted oxidoreductases (related to aryl-alcohol dehydrogenases):Phosphomannomutase:ABC-type multidrug transport system, ATPase and permease components:Uncharacterized Fe-S protein:Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases:Cation transport ATPase:ATPase related to the helicase subunit of the Holliday junction resolvase:Uncharacterized protein conserved in bacteria:Sugar phosphate permease:Cell cycle control, cell division, chromosome partitioning:Carbohydrate transport and metabolism:Coenzyme transport and metabolism:Lipid transport and metabolism:Translation, ribosomal structure and biogenesis:Replication, recombination and repair:Posttranslational modification, protein turnover, chaperones:Inorganic ion transport and metabolism:Ascorbate and aldarate metabolism:Bisphenol degradation:Amino sugar and nucleotide sugar metabolism:Polycyclic aromatic hydrocarbon degradation:Aminobenzoate degradation:One carbon pool by folate:Terpenoid backbone biosynthesis:Limonene and pinene degradation:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:ABC transporters:Function unknown:ispF:TIGR00276:gcp_kae1:crcB:efflux_EmrB:ksgA:glmM:ATPase_P-type:MTHFS_bact:lucif_BA3436:Defense mechanisms:Information storage and processing:Carbohydrate Metabolism:Metabolism of Cofactors and Vitamins:Metabolism of Terpenoids and Polyketides:Xenobiotics Biodegradation and Metabolism:Environmental Information Processing:Membrane Transport:Global:Metabolism:Central intermediary metabolism:One-carbon metabolism:Amino sugars:Energy metabolism:Electron transport:Protein synthesis:tRNA and rRNA base modification:Protein fate:Degradation of proteins, peptides, and glycopeptides:Transport and binding proteins:Other:Unknown function:Enzymes of unknown specificity:General:Biosynthesis of cofactors, prosthetic groups, and carriers:Other:Metabolism:Cellular processes and signaling:Metabolism:Poorly characterized" 395 "Histidinol phosphatase and related phosphatases:Acetyltransferases:Cytosine/adenosine deaminases:Predicted transcriptional regulators:Enoyl-CoA hydratase/carnithine racemase:Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases):Oligoendopeptidase F:Amidases related to nicotinamidase:Periplasmic molybdate-binding protein/domain:Cyclopropane fatty acid synthase and related methyltransferases:Uncharacterized protein conserved in bacteria:Amino acid transport and metabolism:Nucleotide transport and metabolism:Lipid transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:Cell wall/membrane/envelope biogenesis:Inorganic ion transport and metabolism:Fatty acid biosynthesis:Fatty acid metabolism:Valine leucine and isoleucine degradation:Geraniol degradation:Lysine degradation:Tyrosine metabolism:Benzoate degradation:Tryptophan metabolism:beta-Alanine metabolism:Pyruvate metabolism:Naphthalene degradation:Aminobenzoate degradation:Propanoate metabolism:Ethylbenzene degradation:Butanoate metabolism:Limonene and pinene degradation:Biosynthesis of unsaturated fatty acids:Biosynthesis of siderophore group nonribosomal peptides:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:Function unknown:Histidinol-ppas:excise:3oxo_ACP_reduc:M3_not_pepF:Cellular processes and signaling:Information storage and processing:General:Unknown function:Biosynthesis:Fatty acid and phospholipid metabolism:Metabolism:Metabolism:Global:Xenobiotics Biodegradation and Metabolism:Metabolism of Terpenoids and Polyketides:Metabolism of Other Amino Acids:Amino Acid Metabolism:Lipid Metabolism:Poorly characterized:Carbohydrate Metabolism:Metabolism" 396 "Uracil phosphoribosyltransferase:Predicted membrane protein:Sugar kinases, ribokinase family:Fucose permease:FOG: CheY-like receiver:Methyl-accepting chemotaxis protein:Transcriptional regulator:Flagellin-specific chaperone FliS:Predicted RNA-binding protein:Anaerobic C4-dicarboxylate transporter:Nucleotide transport and metabolism:Carbohydrate transport and metabolism:Transcription:Cell motility:Posttranslational modification, protein turnover, chaperones:Fructose and mannose metabolism:Pyrimidine metabolism:Starch and sucrose metabolism:Amino sugar and nucleotide sugar metabolism:Glycerolipid metabolism:Glycerophospholipid metabolism:Metabolic pathways:Two-component system:Bacterial chemotaxis:Flagellar assembly:General function prediction only:Function unknown:Signal transduction mechanisms:TIGR00023:lytR_cpsA_psr:Dcu:upp:Intracellular trafficking, secretion, and vesicular transport:Cellular processes and signaling:Metabolism:Poorly characterized:Information storage and processing:Carbohydrates, organic alcohols, and acids:Transport and binding proteins:Other:Regulatory functions:Metabolism:Global:Salvage of nucleosides and nucleotides:Purines, pyrimidines, nucleosides, and nucleotides:Biosynthesis:Fatty acid and phospholipid metabolism:Cell Motility:Cellular Processes:Metabolism:Signal Transduction:Environmental Information Processing:Nucleotide Metabolism:Lipid Metabolism:Carbohydrate Metabolism" 397 "Molecular chaperone (small heat shock protein):Glycine/serine hydroxymethyltransferase:SAM-dependent methyltransferases:Aspartokinases:Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs:Squalene cyclase:Aspartate racemase:FOG: GGDEF domain:Pyruvate decarboxylase and related thiamine pyrophosphate-requiring enzymes:ABC-type proline/glycine betaine transport system, permease component:Site-specific recombinase XerD:Amino acid transport and metabolism:Carbohydrate transport and metabolism:Coenzyme transport and metabolism:Lipid transport and metabolism:Transcription:Replication, recombination and repair:Cell wall/membrane/envelope biogenesis:Posttranslational modification, protein turnover, chaperones:Alanine aspartate and glutamate metabolism:Glycine serine and threonine metabolism:Cysteine and methionine metabolism:Lysine biosynthesis:Tryptophan metabolism:Cyanoamino acid metabolism:One carbon pool by folate:Methane metabolism:Nitrogen metabolism:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:ABC transporters:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:Signal transduction mechanisms:asp_race:GGDEF:asp_kin_monofn:2A0309:squalene_cyclas:cognate_SipW:Metabolism:Energy Metabolism:Amino Acid Metabolism:Metabolism of Other Amino Acids:Metabolism of Cofactors and Vitamins:Environmental Information Processing:Membrane Transport:Global:Metabolism:Energy metabolism:Amino acids and amines:Transport and binding proteins:Amino acids, peptides and amines:Amino acid biosynthesis:Aspartate family:Signal transduction:Other:Information storage and processing:Cellular processes and signaling:Metabolism:Poorly characterized" 398 "Molybdopterin converting factor, large subunit:Lactoylglutathione lyase and related lyases:Asparagine synthase (glutamine-hydrolyzing):NTP pyrophosphohydrolases including oxidative damage repair enzymes:Putative intracellular protease/amidase:Predicted Rossmann fold nucleotide-binding protein involved in DNA uptake:ABC-type multidrug transport system, permease component:Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases):Transcriptional regulators:Putative stress-responsive transcriptional regulator:Homoserine acetyltransferase:Formate/nitrite family of transporters:Arylamine N-acetyltransferase:Amino acid transport and metabolism:Coenzyme transport and metabolism:Lipid transport and metabolism:Transcription:Replication, recombination and repair:Inorganic ion transport and metabolism:Alanine aspartate and glutamate metabolism:Cysteine and methionine metabolism:Nitrogen metabolism:Sulfur metabolism:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:ABC transporters:Sulfur relay system:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:Signal transduction mechanisms:dprA:asn_synth_AEB:Intracellular trafficking, secretion, and vesicular transport:Defense mechanisms:Metabolism:Global:Metabolism:Membrane Transport:Environmental Information Processing:Folding Sorting and Degradation:Genetic Information Processing:Amino Acid Metabolism:Poorly characterized:Energy Metabolism:Metabolism:Cellular processes and signaling:Information storage and processing:Aspartate family:Amino acid biosynthesis:DNA transformation:Cellular processes" 399 "tRNA-dihydrouridine synthase:L-asparaginase/archaeal Glu-tRNAGln amidotransferase subunit D:Molybdenum cofactor biosynthesis enzyme:Predicted metal-dependent hydrolase:Spermidine synthase:Glucosamine 6-phosphate synthetase, contains amidotransferase and phosphosugar isomerase domains:Amino acid transporters:Topoisomerase IA:Na+/proline symporter:2-methylthioadenine synthetase:Predicted xylanase/chitin deacetylase:Transcriptional regulator:Predicted membrane-associated HD superfamily hydrolase:GAF domain-containing protein:Predicted flavoproteins:Tetrahydrodipicolinate N-succinyltransferase:Cell division protein:SH3 domain protein:Cell cycle control, cell division, chromosome partitioning:Amino acid transport and metabolism:Carbohydrate transport and metabolism:Coenzyme transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:Replication, recombination and repair:Cell wall/membrane/envelope biogenesis:Alanine aspartate and glutamate metabolism:Cysteine and methionine metabolism:Lysine biosynthesis:Arginine and proline metabolism:beta-Alanine metabolism:Cyanoamino acid metabolism:Glutathione metabolism:Amino sugar and nucleotide sugar metabolism:Nitrogen metabolism:Metabolic pathways:Biosynthesis of secondary metabolites:ABC transporters:Sulfur relay system:General function prediction only:Signal transduction mechanisms:TIGR00043:TIGR00089:TIGR00275:HDIG:speE:asnASE_I:moaC:sss:2A0302:topA_bact:glmS:DapD_Ac:Cellular processes and signaling:Carbohydrate Metabolism:Energy Metabolism:Amino Acid Metabolism:Metabolism of Other Amino Acids:Genetic Information Processing:Folding Sorting and Degradation:Environmental Information Processing:Membrane Transport:Global:Metabolism:Central intermediary metabolism:Amino sugars:Polyamine biosynthesis:DNA metabolism:DNA replication, recombination, and repair:Protein synthesis:Other:Transport and binding proteins:Amino acids, peptides and amines:Cations and iron carrying compounds:Unknown function:Enzymes of unknown specificity:Biosynthesis of cofactors, prosthetic groups, and carriers:Molybdopterin:Information storage and processing:Metabolism:Metabolism:Poorly characterized" 400 "Energy production and conversion:Acetyl-CoA hydrolase:Pseudouridylate synthases, 23S RNA-specific:Acetyltransferases, including N-acetylases of ribosomal proteins:Phosphoenolpyruvate carboxykinase (ATP):Isocitrate lyase:Uncharacterized protein conserved in bacteria:Translation, ribosomal structure and biogenesis:Glycolysis / Gluconeogenesis:Citrate cycle (TCA cycle):Geraniol degradation:Tyrosine metabolism:Benzoate degradation:Pyruvate metabolism:Naphthalene degradation:Aminobenzoate degradation:Glyoxylate and dicarboxylate metabolism:Ethylbenzene degradation:Limonene and pinene degradation:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:Function unknown:rluA_subfam:pckA:isocit_lyase:M6dom_TIGR03296:YgfH_subfam:Metabolism of Terpenoids and Polyketides:Amino Acid Metabolism:Metabolism:Metabolism:Carbohydrate Metabolism:Energy metabolism:Glycolysis/gluconeogenesis:TCA cycle:Protein synthesis:tRNA and rRNA base modification:Information storage and processing:Metabolism:Poorly characterized:Global:Xenobiotics Biodegradation and Metabolism" 401 "Thymidine phosphorylase:Putative translation initiation inhibitor, yjgF family:Dihydrofolate reductase:Deoxyribose-phosphate aldolase:Predicted hydrolases of the HAD superfamily:Predicted thioesterase:Transcriptional regulator:Acetyltransferases, including N-acetylases of ribosomal proteins:Uncharacterized protein, 4-oxalocrotonate tautomerase homolog:Nucleoside permease:Transcriptional regulators:Dipeptide/tripeptide permease:ABC-type sugar transport systems, ATPase components:Uncharacterized protein conserved in bacteria:Uncharacterized protein conserved in bacteria:Amino acid transport and metabolism:Nucleotide transport and metabolism:Carbohydrate transport and metabolism:Coenzyme transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:Pentose phosphate pathway:Pyrimidine metabolism:Benzoate degradation:Dioxin degradation:One carbon pool by folate:Folate biosynthesis:Metabolic pathways:Microbial metabolism in diverse environments:ABC transporters:Ribosome:General function prediction only:Function unknown:TIGR00004:taut:TIGR00051:Cof-subfamily:deoC:nupC:yjdL_sub1_fam:rpmF_bact:Y_phosphoryl:WXG100_ESAT6:Enzymes of unknown specificity:Carbohydrate Metabolism:Nucleotide Metabolism:Metabolism of Cofactors and Vitamins:Xenobiotics Biodegradation and Metabolism:Genetic Information Processing:Translation:Environmental Information Processing:Membrane Transport:Global:Metabolism:Energy metabolism:Other:Purines, pyrimidines, nucleosides, and nucleotides:Other:Transcription:Degradation of RNA:Protein synthesis:Ribosomal proteins: synthesis and modification:Transport and binding proteins:Amino acids, peptides and amines:Nucleosides, purines and pyrimidines:Unknown function:Metabolism:General:Information storage and processing:Metabolism:Poorly characterized" 402 "Energy production and conversion:Predicted hydrolases of the HAD superfamily:Cytochrome bd-type quinol oxidase, subunit 2:Beta-lactamase class C and other penicillin binding proteins:Predicted transcriptional regulators:Predicted oxidoreductase related to nitroreductase:Phospholipid N-methyltransferase:Arginine degradation protein (predicted deacylase):Amino acid transport and metabolism:Lipid transport and metabolism:Transcription:Oxidative phosphorylation:Benzoate degradation:Dioxin degradation:Metabolic pathways:Microbial metabolism in diverse environments:General function prediction only:spore_VI_D:Defense mechanisms:Metabolism:Energy Metabolism:Xenobiotics Biodegradation and Metabolism:Global:Metabolism:Cellular processes:Sporulation and germination:Information storage and processing:Cellular processes and signaling:Metabolism:Poorly characterized" 403 "Energy production and conversion:Malic enzyme:Pseudouridylate synthases, 23S RNA-specific:2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase:Isochorismate synthase:Phosphotransferase system, fructose-specific IIC component:Putative effector of murein hydrolase:Putative effector of murein hydrolase LrgA:1,4-dihydroxy-2-naphthoate octaprenyltransferase:Uncharacterized homolog of PSP1:Transcriptional regulators:Arabinose efflux permease:Uncharacterized protein conserved in bacteria:Carbohydrate transport and metabolism:Coenzyme transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:Cell wall/membrane/envelope biogenesis:Ubiquinone and other terpenoid-quinone biosynthesis:Pyruvate metabolism:Biosynthesis of siderophore group nonribosomal peptides:Metabolic pathways:Biosynthesis of secondary metabolites:Two-component system:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:Function unknown:rluA_subfam:menD:isochor_syn:menA:Cellular processes and signaling:Carbohydrate Metabolism:Metabolism of Cofactors and Vitamins:Metabolism of Terpenoids and Polyketides:Environmental Information Processing:Signal Transduction:Global:Metabolism:Protein synthesis:tRNA and rRNA base modification:Biosynthesis of cofactors, prosthetic groups, and carriers:Menaquinone and ubiquinone:Information storage and processing:Metabolism:Metabolism:Poorly characterized" 404 "Lactoylglutathione lyase and related lyases:Fructose-2,6-bisphosphatase:Cell division protein FtsI/penicillin-binding protein 2:Acetyltransferases, including N-acetylases of ribosomal proteins:ABC-type oligopeptide transport system, periplasmic component:Antirepressor regulating drug resistance, predicted signal transduction N-terminal membrane component:Amino acid transport and metabolism:Carbohydrate transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:Cell wall/membrane/envelope biogenesis:Glycolysis / Gluconeogenesis:Methane metabolism:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:ABC transporters:Signal transduction mechanisms:Cellular processes and signaling:Carbohydrate Metabolism:Energy Metabolism:Environmental Information Processing:Membrane Transport:Global:Metabolism:Information storage and processing:Metabolism:Metabolism" 405 "Energy production and conversion:Uncharacterized conserved protein:NTP pyrophosphohydrolases including oxidative damage repair enzymes:ABC-type antimicrobial peptide transport system, permease component:DNA polymerase sliding clamp subunit (PCNA homolog):Permeases of the drug/metabolite transporter (DMT) superfamily:Na+-dependent transporters of the SNF family:Membrane-fusion protein:Gamma-aminobutyrate permease and related permeases:Branched-chain amino acid permeases:Putative threonine efflux protein:DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog:Heme/copper-type cytochrome/quinol oxidase, subunit 3:Molybdopterin converting factor, small subunit:Uncharacterized small protein:Rhodanese-related sulfurtransferase:Heme/copper-type cytochrome/quinol oxidase, subunit 4:Uncharacterized protein conserved in bacteria:Predicted membrane protein:Amino acid transport and metabolism:Carbohydrate transport and metabolism:Coenzyme transport and metabolism:Transcription:Replication, recombination and repair:Cell wall/membrane/envelope biogenesis:Inorganic ion transport and metabolism:Oxidative phosphorylation:Purine metabolism:Pyrimidine metabolism:Cysteine and methionine metabolism:Metabolic pathways:RNA polymerase:DNA replication:Mismatch repair:Homologous recombination:Sulfur relay system:General function prediction only:Function unknown:dnan:livcs:LPXTG_anchor:moaD:spore_sigH:CoxD_Bacillus:Defense mechanisms:Molybdopterin:Energy Metabolism:Nucleotide Metabolism:Amino Acid Metabolism:Genetic Information Processing:Transcription:Folding Sorting and Degradation:Replication and Repair:Global:Metabolism:Energy metabolism:Electron transport:DNA metabolism:DNA replication, recombination, and repair:Transport and binding proteins:Amino acids, peptides and amines:Cellular processes:Sporulation and germination:Biosynthesis of cofactors, prosthetic groups, and carriers:Metabolism:Cell envelope:Other:Information storage and processing:Cellular processes and signaling:Metabolism:Poorly characterized" 406 "Energy production and conversion:Xaa-Pro aminopeptidase:Putative translation factor (SUA5):Predicted S-adenosylmethionine-dependent methyltransferase involved in cell envelope biogenesis:Adenine/guanine phosphoribosyltransferases and related PRPP-binding proteins:Superfamily II DNA/RNA helicases, SNF2 family:Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain:3-dehydroquinate dehydratase II:Nitroreductase:Predicted RNA-binding protein homologous to eukaryotic snRNP:Small primase-like proteins (Toprim domain):Uncharacterized protein conserved in bacteria:4-diphosphocytidyl-2C-methyl-D-erythritol 2-phosphate synthase:Cell division initiation protein:Uncharacterized protein conserved in bacteria:Cell cycle control, cell division, chromosome partitioning:Amino acid transport and metabolism:Nucleotide transport and metabolism:Lipid transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:Replication, recombination and repair:Cell wall/membrane/envelope biogenesis:Phenylalanine tyrosine and tryptophan biosynthesis:Terpenoid backbone biosynthesis:Metabolic pathways:Biosynthesis of secondary metabolites:Function unknown:Signal transduction mechanisms:TIGR00006:TIGR00057:ispE:5S_RNA_mat_M5:aroQ:purR_Bsub:DivI1A_domain:Metabolism:Cellular processes and signaling:Information storage and processing:Biosynthesis and degradation of murein sacculus and peptidoglycan:Cell envelope:Other:Biosynthesis of cofactors, prosthetic groups, and carriers:Aromatic amino acid family:Amino acid biosynthesis:General:Unknown function:RNA processing:Transcription:DNA interactions:Regulatory functions:Metabolism:Metabolism:Global:Metabolism of Terpenoids and Polyketides:Poorly characterized:Amino Acid Metabolism" 407 "Energy production and conversion:Methionine aminopeptidase:Glutamate synthase domain 2:Imidazoleglycerol-phosphate dehydratase:Biotin-(acetyl-CoA carboxylase) ligase:Lactoylglutathione lyase and related lyases:Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component, and related enzymes:Transcriptional regulator:Serine/threonine protein phosphatase:HD superfamily phosphohydrolases:Na+/alanine symporter:Histidinol phosphatase and related hydrolases of the PHP family:2'-5' RNA ligase:Thiamine pyrophosphokinase:Uracil-DNA glycosylase:Predicted metal-dependent hydrolase with the TIM-barrel fold:Acetyltransferases, including N-acetylases of ribosomal proteins:Xanthine and CO dehydrogenases maturation factor, XdhC/CoxF family:Uncharacterized MobA-related protein:Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS/CutS homologs:AraC-type DNA-binding domain-containing proteins:Predicted ring-cleavage extradiol dioxygenase:Predicted aminoglycoside phosphotransferase:Amino acid transport and metabolism:Coenzyme transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:Replication, recombination and repair:Posttranslational modification, protein turnover, chaperones:Glycolysis / Gluconeogenesis:Citrate cycle (TCA cycle):Purine metabolism:Histidine metabolism:Pyruvate metabolism:Thiamine metabolism:Biotin metabolism:Nitrogen metabolism:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:General function prediction only:Signal transduction mechanisms:birA_ligase:met_pdase_I:agcS:LPXTG_anchor:thi_PPkinase:hisJ_fam:2_5_ligase:spore_dpaB:spore_dpaA:pucB:Poorly characterized:Metabolism:Cellular processes and signaling:Information storage and processing:Other:Cell envelope:Thiamine:Biosynthesis of cofactors, prosthetic groups, and carriers:Sporulation and germination:Cellular processes:Protein modification and repair:Protein fate:RNA processing:Transcription:Metabolism:Metabolism:Global:Metabolism of Cofactors and Vitamins:Amino Acid Metabolism:Nucleotide Metabolism:Energy Metabolism:Carbohydrate Metabolism" 408 "Methionyl-tRNA synthetase:Aspartate/tyrosine/aromatic aminotransferase:Homoserine dehydrogenase:ABC-type dipeptide/oligopeptide/nickel transport systems, permease components:Cystathionine beta-lyases/cystathionine gamma-synthases:ABC-type metal ion transport system, ATPase component:ABC-type metal ion transport system, periplasmic component/surface antigen:Metal-dependent amidase/aminoacylase/carboxypeptidase:ABC-type metal ion transport system, permease component:O-acetylhomoserine sulfhydrylase:ABC-type oligopeptide transport system, periplasmic component:Predicted kinase:Amino acid transport and metabolism:Translation, ribosomal structure and biogenesis:Inorganic ion transport and metabolism:Glycine serine and threonine metabolism:Cysteine and methionine metabolism:Lysine biosynthesis:Selenocompound metabolism:Nitrogen metabolism:Sulfur metabolism:Aminoacyl-tRNA biosynthesis:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:ABC transporters:General function prediction only:metG:OAH_OAS_sulfhy:MTRK:amidohydrolases:Information storage and processing:Metabolism:Poorly characterized:Degradation of proteins, peptides, and glycopeptides:Protein fate:tRNA aminoacylation:Protein synthesis:Metabolism:Global:Membrane Transport:Environmental Information Processing:Metabolism:Translation:Genetic Information Processing:Metabolism of Other Amino Acids:Amino Acid Metabolism:Amino acid biosynthesis:Energy Metabolism:Serine family" 409 "Adenosylmethionine-8-amino-7-oxononanoate aminotransferase:Thiamine monophosphate synthase:ABC-type branched-chain amino acid transport systems, periplasmic component:ABC-type multidrug transport system, ATPase component:Transcriptional regulators of sugar metabolism:Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor):Uncharacterized proteins, homologs of microcin C7 resistance protein MccF:Acetyltransferases, including N-acetylases of ribosomal proteins:Conserved protein/domain typically associated with flavoprotein oxygenases, DIM6/NTAB family:Hydroxyethylthiazole kinase, sugar kinase family:Septum formation initiator:O-Methyltransferase involved in polyketide biosynthesis:Uncharacterized protein conserved in bacteria:Cell cycle control, cell division, chromosome partitioning:Amino acid transport and metabolism:Carbohydrate transport and metabolism:Coenzyme transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:Thiamine metabolism:Metabolic pathways:ABC transporters:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:Function unknown:Signal transduction mechanisms:mthyl_TIGR00027:ant_ant_sig:thiE:thiM:Defense mechanisms:Membrane Transport:Environmental Information Processing:Thiamine:Metabolism of Cofactors and Vitamins:Information storage and processing:Cellular processes and signaling:Metabolism:Poorly characterized:Metabolism:Biosynthesis of cofactors, prosthetic groups, and carriers:Enzymes of unknown specificity:Unknown function:Protein interactions:Regulatory functions:Metabolism:Global" 410 "Membrane protein TerC, possibly involved in tellurium resistance:ABC-type multidrug transport system, ATPase component:Uncharacterized conserved protein:Predicted membrane protein:Arabinose efflux permease:Sortase (surface protein transpeptidase):Predicted membrane protein:Predicted membrane protein:Carbohydrate transport and metabolism:Cell wall/membrane/envelope biogenesis:Inorganic ion transport and metabolism:Function unknown:sortase_fam:LPXTG_anchor:R_switched_YkoY:thiopep_ocin:Defense mechanisms:Other:Cell envelope:Toxin production and resistance:Cellular processes:Protein and peptide secretion and trafficking:Protein fate:Cellular processes and signaling:Metabolism:Poorly characterized" 411 "cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases:Predicted permeases:ABC-type multidrug transport system, ATPase component:Beta-lactamase class C and other penicillin binding proteins:Predicted transcriptional regulators:Uncharacterized protein conserved in bacteria:Transcription:General function prediction only:Function unknown:Signal transduction mechanisms:Defense mechanisms:Information storage and processing:Poorly characterized:Cellular processes and signaling" 412 "Energy production and conversion:Alanyl-tRNA synthetase:Phenylalanyl-tRNA synthetase alpha subunit:Aspartyl/asparaginyl-tRNA synthetases:Isoleucyl-tRNA synthetase:Phenylalanyl-tRNA synthetase beta subunit:Homoserine kinase:Histidyl-tRNA synthetase:Anthranilate/para-aminobenzoate synthases component I:Seryl-tRNA synthetase:Tryptophanyl-tRNA synthetase:Glutamate 5-kinase:Threonyl-tRNA synthetase:Leucyl-tRNA synthetase:Threonine synthase:Valyl-tRNA synthetase:Amino acid transporters:Na+-dependent transporters of the SNF family:Branched-chain amino acid permeases:Na+/H+ antiporter:Asparagine synthetase A:3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase:Amino acid transport and metabolism:Coenzyme transport and metabolism:Translation, ribosomal structure and biogenesis:Alanine aspartate and glutamate metabolism:Glycine serine and threonine metabolism:Valine leucine and isoleucine biosynthesis:Arginine and proline metabolism:Tryptophan metabolism:Phenylalanine tyrosine and tryptophan biosynthesis:Cyanoamino acid metabolism:Methane metabolism:Vitamin B6 metabolism:Nitrogen metabolism:Aminoacyl-tRNA biosynthesis:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:General function prediction only:thrB:trpS:thrC:alaS:ileS:leuS_bact:serS:thrS:valS:hisS:asnS:pheS:pheT_bact:trpE_most:asnA:livcs:antiport_nhaC:proB:DAHP_synth_Bsub:Energy Metabolism:Protein synthesis:tRNA aminoacylation:Transport and binding proteins:Amino acids, peptides and amines:Cations and iron carrying compounds:Amino acid biosynthesis:Aromatic amino acid family:Aspartate family:Glutamate family:Information storage and processing:Metabolism:Poorly characterized:Metabolism:Metabolism:Global:Translation:Genetic Information Processing:Metabolism of Cofactors and Vitamins:Metabolism of Other Amino Acids:Amino Acid Metabolism" 413 "Acetyltransferases:Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases):Sugar phosphate isomerases/epimerases:Predicted HD superfamily hydrolase involved in NAD metabolism:Uncharacterized conserved protein:Lysophospholipase L1 and related esterases:ABC-type uncharacterized transport system, periplasmic component:Amino acid transport and metabolism:Carbohydrate transport and metabolism:Coenzyme transport and metabolism:Lipid transport and metabolism:Fatty acid biosynthesis:Tyrosine metabolism:Benzoate degradation:Pyruvate metabolism:Naphthalene degradation:Aminobenzoate degradation:Ethylbenzene degradation:Limonene and pinene degradation:Biosynthesis of unsaturated fatty acids:Metabolic pathways:Microbial metabolism in diverse environments:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:Function unknown:HDIG:3oxo_ACP_reduc:Metabolism:Biosynthesis:Fatty acid and phospholipid metabolism:Metabolism:Metabolism:Global:Xenobiotics Biodegradation and Metabolism:Metabolism of Terpenoids and Polyketides:Amino Acid Metabolism:Lipid Metabolism:Poorly characterized:Carbohydrate Metabolism" 414 "Ribonuclease HI:Protease subunit of ATP-dependent Clp proteases:HD superfamily phosphohydrolases:ABC-type multidrug transport system, ATPase and permease components:Choline-glycine betaine transporter:Predicted transcriptional regulators:Transcriptional regulators:SOS-response transcriptional repressors (RecA-mediated autopeptidases):Na+/melibiose symporter and related transporters:Methylase involved in ubiquinone/menaquinone biosynthesis:Putative NADPH-quinone reductase (modulator of drug activity B):Sugar phosphate permease:Uncharacterized protein conserved in bacteria:Arabinose efflux permease:Putative regulator of cell autolysis:Predicted membrane protein:Uncharacterized protein conserved in bacteria:Site-specific recombinase XerD:Transcriptional regulator, effector-binding domain/component:Carbohydrate transport and metabolism:Coenzyme transport and metabolism:Transcription:Replication, recombination and repair:Cell wall/membrane/envelope biogenesis:Posttranslational modification, protein turnover, chaperones:Glycerolipid metabolism:Metabolic pathways:ABC transporters:Two-component system:DNA replication:General function prediction only:Function unknown:Signal transduction mechanisms:bcct:T_den_put_tspse:thia_yuaJ:Intracellular trafficking, secretion, and vesicular transport:Defense mechanisms:Cellular processes and signaling:Information storage and processing:Other:Transport and binding proteins:Poorly characterized:Metabolism:Metabolism:Global:Signal Transduction:Membrane Transport:Environmental Information Processing:Replication and Repair:Genetic Information Processing:Metabolism:Lipid Metabolism" 415 "Glycine/serine hydroxymethyltransferase:ABC-type uncharacterized transport system, permease component:Uncharacterized NAD(FAD)-dependent dehydrogenases:Signal transduction histidine kinase:Predicted unusual protein kinase:Uncharacterized membrane protein (homolog of Drosophila rhomboid):Gamma-aminobutyrate permease and related permeases:Uncharacterized protein conserved in bacteria:Site-specific recombinases, DNA invertase Pin homologs:Sugar phosphate permease:Arabinose efflux permease:Transcriptional activator of acetoin/glycerol metabolism:Predicted permease, DMT superfamily:Amino acid transport and metabolism:Carbohydrate transport and metabolism:Transcription:Replication, recombination and repair:Ubiquinone and other terpenoid-quinone biosynthesis:Glycine serine and threonine metabolism:Cyanoamino acid metabolism:One carbon pool by folate:Methane metabolism:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:Function unknown:Signal transduction mechanisms:TIGR00245:CoA_CoA_reduc:cognate_SipW:Cellular processes and signaling:Energy Metabolism:Amino Acid Metabolism:Metabolism of Other Amino Acids:Metabolism of Cofactors and Vitamins:Global:Metabolism:Cellular processes:Detoxification:Hypothetical proteins:Conserved:Information storage and processing:Metabolism:Metabolism:Poorly characterized" 416 "AICAR transformylase/IMP cyclohydrolase PurH (only IMP cyclohydrolase domain in Aful):ABC-type Fe3+-hydroxamate transport system, periplasmic component:Exonuclease III:ABC-type multidrug transport system, ATPase component:Predicted membrane protein:Membrane-bound metallopeptidase:Cell cycle control, cell division, chromosome partitioning:Nucleotide transport and metabolism:Replication, recombination and repair:Inorganic ion transport and metabolism:Purine metabolism:One carbon pool by folate:Metabolic pathways:Biosynthesis of secondary metabolites:ABC transporters:Base excision repair:Function unknown:exoDNase_III:purH:Defense mechanisms:Purine ribonucleotide biosynthesis:Nucleotide Metabolism:Metabolism of Cofactors and Vitamins:Genetic Information Processing:Replication and Repair:Environmental Information Processing:Membrane Transport:Global:Metabolism:Purines, pyrimidines, nucleosides, and nucleotides:Metabolism:DNA metabolism:DNA replication, recombination, and repair:Information storage and processing:Cellular processes and signaling:Metabolism:Poorly characterized" 417 "Phenylalanyl-tRNA synthetase alpha subunit:Phenylalanyl-tRNA synthetase beta subunit:Geranylgeranyl pyrophosphate synthase:ATPase components of ABC transporters with duplicated ATPase domains:Sugar kinases, ribokinase family:Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain:ABC-type sugar transport system, ATPase component:GTPase:Ribose/xylose/arabinose/galactoside ABC-type transport systems, permease components:Predicted HD superfamily hydrolase:Nicotinic acid phosphoribosyltransferase:Transcriptional regulators:Phosphate starvation-inducible protein PhoH, predicted ATPase:ABC-type ribose transport system, auxiliary component:Uncharacterized protein conserved in bacteria:Carbohydrate transport and metabolism:Coenzyme transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:Pentose phosphate pathway:Nicotinate and nicotinamide metabolism:Terpenoid backbone biosynthesis:Aminoacyl-tRNA biosynthesis:Metabolic pathways:Biosynthesis of secondary metabolites:ABC transporters:Two-component system:General function prediction only:Function unknown:Signal transduction mechanisms:pheS:pheT_bact:D_ribokin_bact:Energy metabolism:Metabolism:Global:Signal Transduction:Metabolism:Membrane Transport:Environmental Information Processing:Translation:Genetic Information Processing:Metabolism of Terpenoids and Polyketides:Metabolism of Cofactors and Vitamins:Information storage and processing:Carbohydrate Metabolism:Cellular processes and signaling:Metabolism:Poorly characterized:tRNA aminoacylation:Protein synthesis:Sugars" 418 "Nucleoside-diphosphate-sugar epimerases:UDP-glucose 4-epimerase:ABC-type sulfate/molybdate transport systems, ATPase component:ABC-type polar amino acid transport system, ATPase component:Predicted aminoglycoside phosphotransferase:ABC-type oligopeptide transport system, periplasmic component:Predicted DNA alkylation repair enzyme:Amino acid transport and metabolism:Carbohydrate transport and metabolism:Replication, recombination and repair:Cell wall/membrane/envelope biogenesis:Inorganic ion transport and metabolism:Galactose metabolism:Fatty acid biosynthesis:Amino sugar and nucleotide sugar metabolism:Pyruvate metabolism:Propanoate metabolism:Metabolic pathways:Biosynthesis of secondary metabolites:ABC transporters:General function prediction only:3a0106s01:3a0106s03:spore_V_AC:spore_V_AD:Anions:Carbohydrate Metabolism:Lipid Metabolism:Environmental Information Processing:Membrane Transport:Global:Metabolism:Transport and binding proteins:Metabolism:Cellular processes:Sporulation and germination:Information storage and processing:Cellular processes and signaling:Metabolism:Poorly characterized" 419 "Energy production and conversion:ABC-type Fe3+-siderophore transport system, permease component:ABC-type Fe3+-hydroxamate transport system, periplasmic component:Flavodoxins:Non-ribosomal peptide synthetase modules and related proteins:Peptide arylation enzymes:ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components:Isochorismate hydrolase:Sugar phosphate permease:Uncharacterized enzyme involved in biosynthesis of extracellular polysaccharides:Predicted hydrolase of the alpha/beta superfamily:Uncharacterized protein conserved in bacteria:Uncharacterized protein conserved in bacteria:Leucine-rich repeat (LRR) protein:Cell surface protein:Carbohydrate transport and metabolism:Coenzyme transport and metabolism:Cell wall/membrane/envelope biogenesis:Inorganic ion transport and metabolism:Biosynthesis of siderophore group nonribosomal peptides:Biosynthesis of secondary metabolites:ABC transporters:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:Function unknown:efflux_EmrB:AA-adenyl-dom:flav_short:DHB_AMP_lig:sortase_srtB:IsdE:Cations and iron carrying compounds:Transport and binding proteins:Protein and peptide secretion and trafficking:Protein fate:Electron transport:Energy metabolism:Metabolism:Metabolism:Global:Membrane Transport:Environmental Information Processing:Poorly characterized:Metabolism of Terpenoids and Polyketides:Metabolism:Cellular processes and signaling:Other" 420 "EMAP domain:Lactoylglutathione lyase and related lyases:Predicted phosphatases:Uridine kinase:DNA-directed RNA polymerase specialized sigma subunit:Co/Zn/Cd efflux system component:N-acetylglutamate synthase and related acetyltransferases:Acetyltransferases, including N-acetylases of ribosomal proteins:Dioxygenases related to 2-nitropropane dioxygenase:Lysophospholipase:Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains:Uncharacterized conserved protein:Amino acid transport and metabolism:Nucleotide transport and metabolism:Lipid transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:Inorganic ion transport and metabolism:Pyrimidine metabolism:Pyruvate metabolism:Nitrogen metabolism:Metabolic pathways:RNA polymerase:General function prediction only:Function unknown:Signal transduction mechanisms:sensory_box:CDF:HAD-SF-IA-v1:chap_CsaA:spore_sigF:Poorly characterized:Protein and peptide secretion and trafficking:Protein fate:Small molecule interactions:Regulatory functions:Metabolism:Metabolism:Global:Transcription:Genetic Information Processing:Nucleotide Metabolism:Energy Metabolism:Transport and binding proteins:Carbohydrate Metabolism:Cations and iron carrying compounds:Cellular processes:Sporulation and germination:Unknown function:Enzymes of unknown specificity:Information storage and processing:Cellular processes and signaling:Metabolism" 421 "Aspartate racemase:Serine phosphatase RsbU, regulator of sigma subunit:Transcription:Cell wall/membrane/envelope biogenesis:Alanine aspartate and glutamate metabolism:Signal transduction mechanisms:asp_race:B_ant_repeat:spore_II_E:Cellular processes:Amino Acid Metabolism:Energy metabolism:Amino acids and amines:Metabolism:Sporulation and germination:Information storage and processing:Cellular processes and signaling" 422 "Energy production and conversion:Fructose-2,6-bisphosphatase:Glycerophosphoryl diester phosphodiesterase:Carbonic anhydrases/acetyltransferases, isoleucine patch superfamily:ADP-ribose pyrophosphatase:Lysine efflux permease:Transcriptional regulator:Predicted transcriptional regulators:Uncharacterized protein, involved in the regulation of septum location:Uncharacterized protein conserved in bacteria:Response regulator of the LytR/AlgR family:Uncharacterized conserved protein:Conserved protein containing a Zn-ribbon-like motif, possibly RNA-binding:Nucleotide transport and metabolism:Carbohydrate transport and metabolism:Transcription:Cell wall/membrane/envelope biogenesis:Glycolysis / Gluconeogenesis:Glycerophospholipid metabolism:Methane metabolism:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:General function prediction only:Function unknown:Signal transduction mechanisms:Information storage and processing:Cellular processes and signaling:Metabolism:Global:Metabolism:Lipid Metabolism:Poorly characterized:Energy Metabolism:Metabolism:Carbohydrate Metabolism" 423 "Energy production and conversion:Tyrosyl-tRNA synthetase:Cytidylate kinase:ATPase components of ABC transporters with duplicated ATPase domains:CTP synthase (UTP-ammonia lyase):FKBP-type peptidyl-prolyl cis-trans isomerase (trigger factor):16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases:NADH dehydrogenase, FAD-containing subunit:Predicted transcriptional regulator containing the HTH domain:Fructose-1,6-bisphosphatase/sedoheptulose 1,7-bisphosphatase and related proteins:Uncharacterized protein required for cytochrome oxidase assembly:Membrane protein involved in the export of O-antigen and teichoic acid:DNA-directed RNA polymerase, delta subunit:Nucleotide transport and metabolism:Carbohydrate transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:Posttranslational modification, protein turnover, chaperones:Glycolysis / Gluconeogenesis:Pentose phosphate pathway:Fructose and mannose metabolism:Oxidative phosphorylation:Purine metabolism:Pyrimidine metabolism:Porphyrin and chlorophyll metabolism:Aminoacyl-tRNA biosynthesis:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:Two-component system:RNA polymerase:General function prediction only:cmk:TIGR00093:tig:tyrS:TIGR00281:glpX:PyrG:Information storage and processing:Cellular processes and signaling:Metabolism:Poorly characterized:Metabolism:Global:Signal Transduction:Environmental Information Processing:Metabolism:Translation:Transcription:Genetic Information Processing:Metabolism of Cofactors and Vitamins:Nucleotide Metabolism:Energy Metabolism:Carbohydrate Metabolism:Energy metabolism:Pentose phosphate pathway:Purines, pyrimidines, nucleosides, and nucleotides:Nucleotide and nucleoside interconversions:Pyrimidine ribonucleotide biosynthesis:DNA metabolism:Chromosome-associated proteins:Protein synthesis:tRNA aminoacylation:tRNA and rRNA base modification:Protein fate:Protein folding and stabilization" 424 "Chromatin structure and dynamics:Phosphoribosylformylglycinamidine (FGAM) synthase, synthetase domain:Deacetylases, including yeast histone deacetylase and acetoin utilization protein:Phosphoribosylaminoimidazole (AIR) synthetase:Phosphoribosylaminoimidazolesuccinocarboxamide (SAICAR) synthase:Folate-dependent phosphoribosylglycinamide formyltransferase PurN:Thiamine biosynthesis protein ThiC:Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains):Membrane carboxypeptidase (penicillin-binding protein):Cell division protein FtsI/penicillin-binding protein 2:Flagellar motor switch protein:FOG: GAF domain:Uncharacterized protein conserved in bacteria:Chitinase:Nucleotide transport and metabolism:Carbohydrate transport and metabolism:Coenzyme transport and metabolism:Cell wall/membrane/envelope biogenesis:Cell motility:Purine metabolism:Amino sugar and nucleotide sugar metabolism:One carbon pool by folate:Thiamine metabolism:Metabolic pathways:Biosynthesis of secondary metabolites:Bacterial chemotaxis:Flagellar assembly:Secondary metabolites biosynthesis, transport and catabolism:Function unknown:Signal transduction mechanisms:purC:thiC:PurN:purM:FGAM_synth_II:PBP_1a_fam:Poorly characterized:Metabolism:Cellular processes and signaling:Information storage and processing:Biosynthesis and degradation of murein sacculus and peptidoglycan:Cell envelope:Thiamine:Biosynthesis of cofactors, prosthetic groups, and carriers:Purine ribonucleotide biosynthesis:Purines, pyrimidines, nucleosides, and nucleotides:Metabolism:Metabolism:Global:Cell Motility:Cellular Processes:Metabolism of Cofactors and Vitamins:Nucleotide Metabolism:Carbohydrate Metabolism" 425 "Energy production and conversion:Dihydroorotase and related cyclic amidohydrolases:Dihydroorotate dehydrogenase:Orotidine-5'-phosphate decarboxylase:Carbamoylphosphate synthase large subunit (split gene in MJ):Orotate phosphoribosyltransferase:UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N-acetylglucosamine-1-phosphate transferase:Carbamoylphosphate synthase small subunit:Aspartate carbamoyltransferase, catalytic chain:2-polyprenylphenol hydroxylase and related flavodoxin oxidoreductases:UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase:Cell division protein FtsI/penicillin-binding protein 2:UDP-N-acetylmuramate dehydrogenase:Cation/multidrug efflux pump:N-acetylmuramoyl-L-alanine amidase:Gamma-aminobutyrate permease and related permeases:Cell division septal protein:Pyrimidine operon attenuation protein/uracil phosphoribosyltransferase:Xanthine/uracil permeases:Sugar phosphate permease:Protein containing tetrapyrrole methyltransferase domain and MazG-like (predicted pyrophosphatase) domain:Amino acid transport and metabolism:Nucleotide transport and metabolism:Carbohydrate transport and metabolism:Coenzyme transport and metabolism:Cell wall/membrane/envelope biogenesis:Pyrimidine metabolism:Alanine aspartate and glutamate metabolism:Amino sugar and nucleotide sugar metabolism:Peptidoglycan biosynthesis:Metabolic pathways:General function prediction only:murB:pyrE:mazG:mraY:asp_carb_tr:ncs2:pyrC_multi:pyrD_sub1_fam:murG:CPSaseIIsmall:CPSaseII_lrg:pyrF:spoVD_pbp:Defense mechanisms:Nucleosides, purines and pyrimidines:Transport and binding proteins:Pyrimidine ribonucleotide biosynthesis:Purines, pyrimidines, nucleosides, and nucleotides:Metabolism:Metabolism:Global:Glycan Biosynthesis and Metabolism:Amino Acid Metabolism:Nucleotide Metabolism:Poorly characterized:Carbohydrate Metabolism:Metabolism:Cellular processes and signaling:Biosynthesis and degradation of murein sacculus and peptidoglycan:Cell envelope:General:Unknown function:Sporulation and germination:Cellular processes" 426 "5-enolpyruvylshikimate-3-phosphate synthase:Aspartate-semialdehyde dehydrogenase:Acetyltransferases:Aspartokinases:Preprotein translocase subunit SecA (ATPase, RNA helicase):Uncharacterized conserved protein:Predicted RNA-binding protein homologous to eukaryotic snRNP:Transcriptional regulator:Predicted hydrolase of the HAD superfamily:Dipeptide/tripeptide permease:Cell division initiation protein:Cell cycle control, cell division, chromosome partitioning:Amino acid transport and metabolism:Transcription:Glycine serine and threonine metabolism:Cysteine and methionine metabolism:Lysine biosynthesis:Tyrosine metabolism:Benzoate degradation:Phenylalanine tyrosine and tryptophan biosynthesis:Naphthalene degradation:Aminobenzoate degradation:Ethylbenzene degradation:Limonene and pinene degradation:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:Protein export:Bacterial secretion system:General function prediction only:Function unknown:asp_kin_monofn:yjdL_sub1_fam:secA:asd_B:aroA:HAD-SF-IA-v3:DivI1A_domain:Intracellular trafficking, secretion, and vesicular transport:Aromatic amino acid family:Aspartate family:Information storage and processing:Cellular processes and signaling:Metabolism:Poorly characterized:Enzymes of unknown specificity:Unknown function:Amino acids, peptides and amines:Transport and binding proteins:Protein and peptide secretion and trafficking:Protein fate:Metabolism:Metabolism:Global:Membrane Transport:Environmental Information Processing:Folding Sorting and Degradation:Genetic Information Processing:Xenobiotics Biodegradation and Metabolism:Metabolism of Terpenoids and Polyketides:Amino acid biosynthesis:Amino Acid Metabolism" 427 "Energy production and conversion:Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases:Peptide methionine sulfoxide reductase:ATPases involved in chromosome partitioning:Zn-dependent hydrolases, including glyoxylases:ADP-ribose pyrophosphatase:ABC-type multidrug transport system, ATPase component:Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes:Predicted metal-dependent hydrolase with the TIM-barrel fold:Sugar transferases involved in lipopolysaccharide synthesis:AraC-type DNA-binding domain-containing proteins:Membrane protein involved in the export of O-antigen and teichoic acid:Lyzozyme M1 (1,4-beta-N-acetylmuramidase):Capsular polysaccharide biosynthesis protein:Uncharacterized conserved protein:Cell cycle control, cell division, chromosome partitioning:Nucleotide transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:Cell wall/membrane/envelope biogenesis:Posttranslational modification, protein turnover, chaperones:Glycolysis / Gluconeogenesis:Citrate cycle (TCA cycle):Glycine serine and threonine metabolism:Valine leucine and isoleucine degradation:Arginine and proline metabolism:Phenylalanine metabolism:Tryptophan metabolism:Cyanoamino acid metabolism:Pyruvate metabolism:Aminobenzoate degradation:Styrene degradation:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:ABC transporters:General function prediction only:Function unknown:TIGR00357:lipoamide_DH:Defense mechanisms:Metabolism:Xenobiotics Biodegradation and Metabolism:Metabolism of Other Amino Acids:Amino Acid Metabolism:Poorly characterized:Carbohydrate Metabolism:Metabolism:Cellular processes and signaling:Information storage and processing:Adaptations to atypical conditions:Cellular processes:Metabolism:Global:Membrane Transport:Environmental Information Processing" 428 "Fructose-2,6-bisphosphatase:Dienelactone hydrolase and related enzymes:NTP pyrophosphohydrolases including oxidative damage repair enzymes:Amino acid transporters:Predicted hydrolases of the HAD superfamily:Predicted xylanase/chitin deacetylase:Na+-dependent transporters of the SNF family:5'-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases:Chemotaxis signal transduction protein:Methyl-accepting chemotaxis protein:Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs:Uncharacterized conserved protein:Transcriptional regulators:Acetyltransferases, including N-acetylases of ribosomal proteins:Phenylalanine-4-hydroxylase:Amino acid transport and metabolism:Nucleotide transport and metabolism:Carbohydrate transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:Replication, recombination and repair:Cell motility:Glycolysis / Gluconeogenesis:Purine metabolism:Pyrimidine metabolism:Phenylalanine metabolism:Phenylalanine tyrosine and tryptophan biosynthesis:Methane metabolism:Nicotinate and nicotinamide metabolism:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:Two-component system:Bacterial chemotaxis:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:Function unknown:Signal transduction mechanisms:Cof-subfamily:LPXTG_anchor:spore_ybaN_pdaB:Cellular processes and signaling:Information storage and processing:Other:Cell envelope:Enzymes of unknown specificity:Unknown function:Sporulation and germination:Cellular processes:Metabolism:Metabolism:Global:Cell Motility:Cellular Processes:Signal Transduction:Environmental Information Processing:Metabolism of Cofactors and Vitamins:Amino Acid Metabolism:Nucleotide Metabolism:Energy Metabolism:Poorly characterized:Carbohydrate Metabolism:Metabolism" 429 "Energy production and conversion:Malate/lactate dehydrogenases:Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2:cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases:NAD-dependent aldehyde dehydrogenases:Zn-dependent alcohol dehydrogenases:Cytochrome bd-type quinol oxidase, subunit 1:Cytochrome bd-type quinol oxidase, subunit 2:Oxygen-sensitive ribonucleoside-triphosphate reductase:L-lactate permease:Pyruvate-formate lyase:Molybdopterin converting factor, small subunit:Formate/nitrite family of transporters:Predicted transcriptional regulator:Molybdenum cofactor biosynthesis enzyme:Uncharacterized protein conserved in bacteria:Predicted membrane protein, putative toxin regulator:ABC-type transport system involved in cytochrome bd biosynthesis, fused ATPase and permease components:ABC-type transport system involved in cytochrome bd biosynthesis, ATPase and permease components:Nucleotide transport and metabolism:Coenzyme transport and metabolism:Transcription:Posttranslational modification, protein turnover, chaperones:Inorganic ion transport and metabolism:Glycolysis / Gluconeogenesis:Fatty acid metabolism:Oxidative phosphorylation:Purine metabolism:Pyrimidine metabolism:Cysteine and methionine metabolism:Tyrosine metabolism:Benzoate degradation:Pyruvate metabolism:Dioxin degradation:Chloroalkane and chloroalkene degradation:Naphthalene degradation:Propanoate metabolism:Butanoate metabolism:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:ABC transporters:Sulfur relay system:General function prediction only:Function unknown:Signal transduction mechanisms:cydB:lctP:pyr_form_ly_1:moaD:L-LDH-NAD:NrdD:moaA:CydD:CydC:Information storage and processing:Carbohydrate Metabolism:Energy Metabolism:Lipid Metabolism:Nucleotide Metabolism:Amino Acid Metabolism:Xenobiotics Biodegradation and Metabolism:Genetic Information Processing:Folding Sorting and Degradation:Environmental Information Processing:Membrane Transport:Global:Metabolism:Energy metabolism:Electron transport:Fermentation:Glycolysis/gluconeogenesis:Purines, pyrimidines, nucleosides, and nucleotides:2'-Deoxyribonucleotide metabolism:Transport and binding proteins:Carbohydrates, organic alcohols, and acids:Biosynthesis of cofactors, prosthetic groups, and carriers:Molybdopterin:Metabolism:Cellular processes and signaling:Metabolism:Poorly characterized" 430 "Energy production and conversion:Methionine aminopeptidase:GTPases - translation elongation factors:Ribosomal protein L17:Protease subunit of ATP-dependent Clp proteases:Predicted hydrolase (HAD superfamily):Uncharacterized membrane protein:Tartrate dehydratase alpha subunit/Fumarate hydratase class I, N-terminal domain:Uncharacterized conserved protein:Methylase of polypeptide chain release factors:Predicted glycosyl hydrolase:Predicted membrane protein:Translation, ribosomal structure and biogenesis:Posttranslational modification, protein turnover, chaperones:Citrate cycle (TCA cycle):Chloroalkane and chloroalkene degradation:Carbon fixation pathways in prokaryotes:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:Ribosome:General function prediction only:Function unknown:L17:small_GTP:met_pdase_I:hemK_fam:ttdA_fumA_fumB:rpmJ_bact:HAD-SF-IA-v1:Intracellular trafficking, secretion, and vesicular transport:Metabolism:Poorly characterized:Cellular processes and signaling:Information storage and processing:General:Enzymes of unknown specificity:Unknown function:Protein modification and repair:Protein fate:Ribosomal proteins: synthesis and modification:Metabolism:Metabolism:Global:Protein synthesis:Translation:Genetic Information Processing:Xenobiotics Biodegradation and Metabolism:Energy Metabolism:Carbohydrate Metabolism" 431 "Amino acid transporters:Predicted phosphatases:Na+/proline symporter:Glycosyltransferases, probably involved in cell wall biogenesis:Uncharacterized membrane protein:Chromate transport protein ChrA:Methylase involved in ubiquinone/menaquinone biosynthesis:Predicted membrane protein:Amino acid transport and metabolism:Coenzyme transport and metabolism:Cell wall/membrane/envelope biogenesis:Inorganic ion transport and metabolism:Fructose and mannose metabolism:Glyoxylate and dicarboxylate metabolism:Metabolic pathways:General function prediction only:Function unknown:2A51:LPXTG_anchor:HAD-SF-IA-v1:Cellular processes and signaling:Carbohydrate Metabolism:Global:Metabolism:Transport and binding proteins:Anions:Unknown function:Enzymes of unknown specificity:Cell envelope:Other:Metabolism:Metabolism:Poorly characterized" 432 "Chloride channel protein EriC:tRNA-dihydrouridine synthase:UDP-N-acetylmuramate dehydrogenase:N-acetylmuramoyl-L-alanine amidase:Transcriptional regulator:Uncharacterized protein conserved in bacteria:Transcriptional regulators:Transcriptional regulators:GTPases:Lysophospholipase:Predicted ABC-type exoprotein transport system, permease component:Predicted esterase of the alpha-beta hydrolase superfamily:Predicted membrane protein:Lipid transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:Cell wall/membrane/envelope biogenesis:Inorganic ion transport and metabolism:Amino sugar and nucleotide sugar metabolism:Peptidoglycan biosynthesis:Metabolic pathways:General function prediction only:Function unknown:murB:lytR_cpsA_psr:int_mem_ywzB:GTP_HflX:Intracellular trafficking, secretion, and vesicular transport:Poorly characterized:Carbohydrate Metabolism:Glycan Biosynthesis and Metabolism:Global:Metabolism:Regulatory functions:Other:Unknown function:General:Cell envelope:Biosynthesis and degradation of murein sacculus and peptidoglycan:Information storage and processing:Cellular processes and signaling:Metabolism:Metabolism" 433 "Glycosyltransferases involved in cell wall biogenesis:Transcriptional regulator:Phosphatidylserine decarboxylase:Predicted periplasmic solute-binding protein:Predicted flavoproteins:Predicted ATPase involved in cell division:Dipeptide/tripeptide permease:Uncharacterized protein conserved in bacteria:Uncharacterized protein conserved in bacteria:Uncharacterized protein conserved in bacteria:Cell cycle control, cell division, chromosome partitioning:Amino acid transport and metabolism:Lipid transport and metabolism:Transcription:Cell wall/membrane/envelope biogenesis:Glycerophospholipid metabolism:Metabolic pathways:ABC transporters:General function prediction only:Function unknown:PS_decarb:TIGR00247:TIGR00275:FtsE:Poorly characterized:Information storage and processing:Enzymes of unknown specificity:Unknown function:Conserved:Hypothetical proteins:Cell division:Cellular processes:Biosynthesis:Fatty acid and phospholipid metabolism:Metabolism:Metabolism:Global:Membrane Transport:Environmental Information Processing:Cellular processes and signaling:Lipid Metabolism:Metabolism" 434 "Energy production and conversion:Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases:Glycerophosphoryl diester phosphodiesterase:Signal transduction histidine kinase:ABC-type branched-chain amino acid transport systems, periplasmic component:Amino acid transporters:Methyl-accepting chemotaxis protein:Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases):ABC-type dipeptide/oligopeptide/nickel transport systems, permease components:ATPases involved in chromosome partitioning:NADH dehydrogenase, FAD-containing subunit:Putative effector of murein hydrolase:Putative effector of murein hydrolase LrgA:Beta-lactamase class C and other penicillin binding proteins:Uncharacterized conserved protein:Uncharacterized protein conserved in bacteria:Uncharacterized protein conserved in bacteria:ABC-type oligopeptide transport system, ATPase component:Cell cycle control, cell division, chromosome partitioning:Amino acid transport and metabolism:Nucleotide transport and metabolism:Carbohydrate transport and metabolism:Lipid transport and metabolism:Cell wall/membrane/envelope biogenesis:Cell motility:Inorganic ion transport and metabolism:Oxidative phosphorylation:Glycerophospholipid metabolism:ABC transporters:Two-component system:Bacterial chemotaxis:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:Function unknown:Signal transduction mechanisms:Defense mechanisms:Metabolism:Cellular processes and signaling:Cell Motility:Cellular Processes:Signal Transduction:Membrane Transport:Environmental Information Processing:Lipid Metabolism:Energy Metabolism:Metabolism:Poorly characterized" 435 "Zn-dependent hydrolases, including glyoxylases:Beta-lactamase class C and other penicillin binding proteins:Uncharacterized conserved protein:Putative primosome component and related proteins:Antirepressor regulating drug resistance, predicted signal transduction N-terminal membrane component:Uncharacterized protein conserved in bacteria:Uncharacterized protein conserved in bacteria:Transcription:Replication, recombination and repair:Pyruvate metabolism:General function prediction only:Function unknown:Signal transduction mechanisms:DnaD_dom:yxeA_fam:Defense mechanisms:Conserved:Carbohydrate Metabolism:Information storage and processing:Cellular processes and signaling:Poorly characterized:Metabolism:Hypothetical proteins:Prophage functions:Mobile and extrachromosomal element functions" 436 "Energy production and conversion:Predicted permeases:Cytochrome c biogenesis protein:Zn-dependent alcohol dehydrogenases, class III:Na+/alanine symporter:DNA-directed RNA polymerase specialized sigma subunit:Peroxiredoxin:Transcriptional regulator:Glutaminase:Predicted membrane protein:Predicted ornithine cyclodeaminase, mu-crystallin homolog:Lyzozyme M1 (1,4-beta-N-acetylmuramidase):Uncharacterized protein conserved in bacteria:Proline racemase:Uncharacterized protein conserved in bacteria:Amino acid transport and metabolism:Transcription:Cell wall/membrane/envelope biogenesis:Posttranslational modification, protein turnover, chaperones:Glycolysis / Gluconeogenesis:Fatty acid metabolism:Alanine aspartate and glutamate metabolism:Arginine and proline metabolism:Tyrosine metabolism:Benzoate degradation:D-Glutamine and D-glutamate metabolism:Chloroalkane and chloroalkene degradation:Naphthalene degradation:Aminobenzoate degradation:Ethylbenzene degradation:Limonene and pinene degradation:Nitrogen metabolism:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:Two-component system:RNA polymerase:General function prediction only:Function unknown:agcS:DnaD_dom:spore_sigmaK:spore_III_AA:Gln_ase:Metabolism of Other Amino Acids:Amino Acid Metabolism:Lipid Metabolism:Energy Metabolism:Signal Transduction:Carbohydrate Metabolism:Global:Metabolism:Energy metabolism:Amino acids and amines:Cellular processes:Sporulation and germination:Mobile and extrachromosomal element functions:Prophage functions:Information storage and processing:Cellular processes and signaling:Metabolism:Poorly characterized:Environmental Information Processing:Transcription:Genetic Information Processing:Metabolism:Xenobiotics Biodegradation and Metabolism:Metabolism of Terpenoids and Polyketides" 437 "Pyrroline-5-carboxylate reductase:Nucleoside-diphosphate-sugar epimerases:Zn-dependent hydrolases, including glyoxylases:ABC-type sulfate/molybdate transport systems, ATPase component:Hemolysins and related proteins containing CBS domains:Phosphotransferase system cellobiose-specific component IIB:Acetyltransferases, including N-acetylases of ribosomal proteins:Predicted N-acetylglucosamine kinase:Predicted aminoglycoside phosphotransferase:Predicted DNA alkylation repair enzyme:Amino acid transport and metabolism:Carbohydrate transport and metabolism:Translation, ribosomal structure and biogenesis:Replication, recombination and repair:Cell wall/membrane/envelope biogenesis:Inorganic ion transport and metabolism:Galactose metabolism:Penicillin and cephalosporin biosynthesis:Tyrosine metabolism:Benzoate degradation:Amino sugar and nucleotide sugar metabolism:Naphthalene degradation:Aminobenzoate degradation:Ethylbenzene degradation:Limonene and pinene degradation:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:ABC transporters:Two-component system:Phosphotransferase system (PTS):General function prediction only:3a0106s01:3a0106s03:spore_IV_A:Information storage and processing:Carbohydrate Metabolism:Amino Acid Metabolism:Metabolism of Terpenoids and Polyketides:Biosynthesis of Other Secondary Metabolites:Xenobiotics Biodegradation and Metabolism:Environmental Information Processing:Membrane Transport:Signal Transduction:Global:Metabolism:Transport and binding proteins:Anions:Cellular processes:Sporulation and germination:Metabolism:Cellular processes and signaling:Metabolism:Poorly characterized" 438 "Energy production and conversion:Fumarase:Superoxide dismutase:Predicted permease:Predicted transcriptional regulators:Signal transduction histidine kinase:Uncharacterized conserved protein:Hydrolases of the alpha/beta superfamily:Amidases related to nicotinamidase:DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog:Na+/melibiose symporter and related transporters:Uncharacterized conserved protein:Uncharacterized protein conserved in bacteria:Uncharacterized protein conserved in bacteria:Negative regulator of genetic competence, sporulation and motility:Carbohydrate transport and metabolism:Transcription:Cell motility:Posttranslational modification, protein turnover, chaperones:Inorganic ion transport and metabolism:Citrate cycle (TCA cycle):Carbon fixation pathways in prokaryotes:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:Two-component system:RNA polymerase:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:Function unknown:Signal transduction mechanisms:TIGR00278:fumC_II:nudix_YtkD:sigma70-ECF:Cellular processes and signaling:Carbohydrate Metabolism:Energy Metabolism:Genetic Information Processing:Transcription:Environmental Information Processing:Signal Transduction:Global:Metabolism:Energy metabolism:TCA cycle:DNA metabolism:DNA replication, recombination, and repair:Hypothetical proteins:Conserved:Information storage and processing:Metabolism:Metabolism:Poorly characterized" 439 "Energy production and conversion:Uncharacterized conserved protein:Zn-dependent hydrolases, including glyoxylases:Exopolyphosphatase-related proteins:Hypoxanthine-guanine phosphoribosyltransferase:Signal peptidase I:Nitroreductase:Oligoendopeptidase F:Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily:Predicted pyrophosphatase:Phage shock protein A (IM30), suppresses sigma54-dependent transcription:Transcriptional regulators:Lysophospholipase:Arabinose efflux permease:Uncharacterized protein involved in tellurite resistance:Negative regulator of genetic competence, sporulation and motility:Amino acid transport and metabolism:Nucleotide transport and metabolism:Carbohydrate transport and metabolism:Lipid transport and metabolism:Transcription:Cell wall/membrane/envelope biogenesis:Cell motility:Posttranslational modification, protein turnover, chaperones:Inorganic ion transport and metabolism:Purine metabolism:Glycerophospholipid metabolism:Metabolic pathways:Biosynthesis of secondary metabolites:Two-component system:Protein export:General function prediction only:Function unknown:Signal transduction mechanisms:pepF:HGPRTase:sigpep_I_bact:Intracellular trafficking, secretion, and vesicular transport:Protein fate:Salvage of nucleosides and nucleotides:Purines, pyrimidines, nucleosides, and nucleotides:Metabolism:Global:Signal Transduction:Environmental Information Processing:Metabolism:Folding Sorting and Degradation:Genetic Information Processing:Nucleotide Metabolism:Lipid Metabolism:Poorly characterized:Metabolism:Cellular processes and signaling:Information storage and processing:Degradation of proteins, peptides, and glycopeptides:Protein and peptide secretion and trafficking" 440 "Energy production and conversion:NADPH:quinone reductase and related Zn-dependent oxidoreductases:Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain:Predicted hydrolase (HAD superfamily):Transcriptional regulator:Predicted transcriptional regulators:Predicted transcriptional regulators:Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain:Predicted transcriptional regulator:Predicted transcriptional regulator:Signal transduction histidine kinase, nitrogen specific:Signal transduction histidine kinase:Signal transduction histidine kinase:Uncharacterized conserved protein:Transcription:Chloroalkane and chloroalkene degradation:Metabolic pathways:Microbial metabolism in diverse environments:Two-component system:General function prediction only:Function unknown:Signal transduction mechanisms:HAD-SF-IA-v3:Global:Signal Transduction:Environmental Information Processing:Metabolism:Xenobiotics Biodegradation and Metabolism:Poorly characterized:Metabolism:Cellular processes and signaling:Information storage and processing:Enzymes of unknown specificity:Unknown function:Metabolism" 441 "Mg2+ and Co2+ transporters:Signal transduction histidine kinase:Putative intracellular protease/amidase:Catalase:DNA-directed RNA polymerase specialized sigma subunit:Methylase of chemotaxis methyl-accepting proteins:Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor):Anti-sigma regulatory factor (Ser/Thr protein kinase):Bacterioferritin (cytochrome b1):Serine phosphatase RsbU, regulator of sigma subunit:Transcription:Cell motility:Inorganic ion transport and metabolism:Tryptophan metabolism:Methane metabolism:Metabolic pathways:Microbial metabolism in diverse environments:Two-component system:Bacterial chemotaxis:RNA polymerase:General function prediction only:Signal transduction mechanisms:ant_ant_sig:PfpI:rsbW_low_gc:sigma70-ECF:Cellular processes and signaling:Energy Metabolism:Amino Acid Metabolism:Genetic Information Processing:Transcription:Environmental Information Processing:Signal Transduction:Cellular Processes:Cell Motility:Global:Metabolism:Regulatory functions:Protein interactions:Protein fate:Degradation of proteins, peptides, and glycopeptides:Information storage and processing:Metabolism:Metabolism:Poorly characterized" 442 "Pentose-5-phosphate-3-epimerase:Predicted hydrolases of the HAD superfamily:Parvulin-like peptidyl-prolyl isomerase:Transcriptional regulator:D-alanyl-D-alanine carboxypeptidase:Predicted membrane protein:SH3 domain protein:Sortase (surface protein transpeptidase):Uncharacterized protein conserved in bacteria:Uncharacterized conserved protein:Carbohydrate transport and metabolism:Transcription:Cell wall/membrane/envelope biogenesis:Posttranslational modification, protein turnover, chaperones:Pentose phosphate pathway:Pentose and glucuronate interconversions:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:General function prediction only:Function unknown:Signal transduction mechanisms:Cof-subfamily:lytR_cpsA_psr:sortase_fam:rpe:TIGR03833:Poorly characterized:Carbohydrate Metabolism:Global:Metabolism:Energy metabolism:Pentose phosphate pathway:Regulatory functions:Other:Protein fate:Protein and peptide secretion and trafficking:Hypothetical proteins:Conserved:Unknown function:Enzymes of unknown specificity:Information storage and processing:Cellular processes and signaling:Metabolism:Metabolism" 443 "Energy production and conversion:Transcriptional regulator:Uncharacterized membrane-associated protein:Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily):ABC-type Fe3+-hydroxamate transport system, periplasmic component:Nitroreductase:Gamma-aminobutyrate permease and related permeases:ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components:Peroxiredoxin:Transcriptional regulator:Uncharacterized conserved protein:Predicted transcriptional regulators:SOS-response transcriptional repressors (RecA-mediated autopeptidases):Predicted membrane protein:Uncharacterized conserved protein:Predicted permease, cadmium resistance protein:Uncharacterized protein conserved in bacteria:Amino acid transport and metabolism:Coenzyme transport and metabolism:Transcription:Posttranslational modification, protein turnover, chaperones:Inorganic ion transport and metabolism:ABC transporters:General function prediction only:Function unknown:Signal transduction mechanisms:Metabolism:Cellular processes and signaling:Poorly characterized:Membrane Transport:Environmental Information Processing:Information storage and processing" 444 "ATPase components of various ABC-type transport systems, contain duplicated ATPase:Oligoendopeptidase F:DNA-directed RNA polymerase specialized sigma subunit:Transcriptional regulator:D-alanyl-D-alanine carboxypeptidase:ABC-type sugar transport system, periplasmic component:Uncharacterized protein conserved in bacteria:Putative primosome component and related proteins:Amino acid transport and metabolism:Carbohydrate transport and metabolism:Transcription:Replication, recombination and repair:Cell wall/membrane/envelope biogenesis:Peptidoglycan biosynthesis:Metabolic pathways:ABC transporters:RNA polymerase:General function prediction only:Function unknown:DnaD_dom:spore_sigmaK:spore_III_AA:Information storage and processing:Glycan Biosynthesis and Metabolism:Genetic Information Processing:Transcription:Environmental Information Processing:Membrane Transport:Global:Metabolism:Cellular processes:Sporulation and germination:Mobile and extrachromosomal element functions:Prophage functions:Metabolism:Cellular processes and signaling:Metabolism:Poorly characterized" 445 "Energy production and conversion:Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase]:Trk-type K+ transport systems, membrane components:Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II:Glutamate dehydrogenase/leucine dehydrogenase:Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component, and related enzymes:2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, and related enzymes:Superoxide dismutase:5'-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases:Predicted 6-phosphogluconate dehydrogenase:Threonine dehydrogenase and related Zn-dependent dehydrogenases:Sugar (pentulose and hexulose) kinases:Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily:Uncharacterized protein required for formate dehydrogenase activity:Formate/nitrite family of transporters:Uncharacterized conserved protein:H+/gluconate symporter and related permeases:Molybdenum cofactor biosynthesis enzyme:Uncharacterized anaerobic dehydrogenase:Alpha-acetolactate decarboxylase:Uncharacterized conserved protein:Amino acid transport and metabolism:Nucleotide transport and metabolism:Carbohydrate transport and metabolism:Coenzyme transport and metabolism:Lipid transport and metabolism:Cell wall/membrane/envelope biogenesis:Inorganic ion transport and metabolism:Citrate cycle (TCA cycle):Pentose phosphate pathway:Purine metabolism:Pyrimidine metabolism:Alanine aspartate and glutamate metabolism:Valine leucine and isoleucine biosynthesis:Lysine degradation:Arginine and proline metabolism:Tryptophan metabolism:Glutathione metabolism:Glyoxylate and dicarboxylate metabolism:Butanoate metabolism:C5-Branched dibasic acid metabolism:Methane metabolism:Nicotinate and nicotinamide metabolism:Pantothenate and CoA biosynthesis:Nitrogen metabolism:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:Sulfur relay system:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:Function unknown:fdhD_narQ:2oxo_dh_E1:gntP:gnd_rel:2a38:acetolac_decarb:gntK_FGGY:sucB:Fdh-alpha:acolac_catab:moaA:Metabolism of Other Amino Acids:Amino Acid Metabolism:Nucleotide Metabolism:Energy Metabolism:Energy metabolism:Carbohydrate Metabolism:Electron transport:Fermentation:Pentose phosphate pathway:TCA cycle:Sugars:Transport and binding proteins:Carbohydrates, organic alcohols, and acids:Cations and iron carrying compounds:Biosynthesis of cofactors, prosthetic groups, and carriers:Molybdopterin:Cellular processes and signaling:Metabolism:Poorly characterized:Metabolism:Global:Folding Sorting and Degradation:Genetic Information Processing:Metabolism:Metabolism of Cofactors and Vitamins" 446 "Asparagine synthase (glutamine-hydrolyzing):Predicted transcriptional regulators:Predicted transcriptional regulators:ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components:Phosphotransferase system cellobiose-specific component IIA:Uracil-DNA glycosylase:Uncharacterized conserved protein (some members contain a von Willebrand factor type A (vWA) domain):Inosine-uridine nucleoside N-ribohydrolase:Phage-related protein:L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily:Predicted integral membrane protein:Amino acid transport and metabolism:Nucleotide transport and metabolism:Carbohydrate transport and metabolism:Coenzyme transport and metabolism:Transcription:Replication, recombination and repair:Cell wall/membrane/envelope biogenesis:Inorganic ion transport and metabolism:Purine metabolism:Alanine aspartate and glutamate metabolism:Nicotinate and nicotinamide metabolism:Nitrogen metabolism:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:ABC transporters:Phosphotransferase system (PTS):General function prediction only:Function unknown:asn_synth_AEB:put_anti_recept:spore_ger_x_C:Amino acid biosynthesis:Prophage functions:Mobile and extrachromosomal element functions:Sporulation and germination:Cellular processes:Metabolism:Global:Metabolism:Membrane Transport:Environmental Information Processing:Metabolism of Cofactors and Vitamins:Amino Acid Metabolism:Nucleotide Metabolism:Cellular processes and signaling:Energy Metabolism:Metabolism:Poorly characterized:Information storage and processing:Aspartate family" 447 "Predicted sugar kinase:DNA primase (bacterial type):Exoribonuclease R:Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain:Bacterial cell division membrane protein:N-acetylglucosamine-1-phosphate uridyltransferase (contains nucleotidyltransferase and I-patch acetyltransferase domains):Uncharacterized protein conserved in bacteria:Small primase-like proteins (Toprim domain):Site-specific recombinase XerD:Cell cycle control, cell division, chromosome partitioning:Carbohydrate transport and metabolism:Transcription:Replication, recombination and repair:Cell wall/membrane/envelope biogenesis:Amino sugar and nucleotide sugar metabolism:Nicotinate and nicotinamide metabolism:Metabolic pathways:Two-component system:RNA degradation:DNA replication:Function unknown:Signal transduction mechanisms:5S_RNA_mat_M5:3_prime_RNase:glmU:dnaG:recomb_XerC:Metabolism:Carbohydrate Metabolism:Metabolism of Cofactors and Vitamins:Genetic Information Processing:Folding Sorting and Degradation:Replication and Repair:Environmental Information Processing:Signal Transduction:Global:Metabolism:Central intermediary metabolism:Amino sugars:DNA metabolism:DNA replication, recombination, and repair:Transcription:Degradation of RNA:RNA processing:Information storage and processing:Cellular processes and signaling:Metabolism:Poorly characterized" 448 "ABC-type amino acid transport/signal transduction systems, periplasmic component/domain:Membrane protein TerC, possibly involved in tellurium resistance:Na+/H+ antiporter NhaD and related arsenite permeases:Na+/alanine symporter:Transcriptional regulator:Amino acid transport and metabolism:Transcription:Inorganic ion transport and metabolism:ABC transporters:Signal transduction mechanisms:lytR_cpsA_psr:agcS:tiny_TM_bacill:R_switched_YjbE:exospore_TM:Information storage and processing:Membrane Transport:Regulatory functions:Other:Hypothetical proteins:Conserved:Environmental Information Processing:Cellular processes and signaling:Metabolism" 449 "Energy production and conversion:Mg-dependent DNase:Thiol-disulfide isomerase and thioredoxins:Amino acid transporters:ABC-type nitrate/sulfonate/bicarbonate transport system, permease component:ABC-type Fe3+-hydroxamate transport system, periplasmic component:Predicted transcriptional regulators:Signal transduction histidine kinase:Mannose-6-phosphate isomerase:Glycine/D-amino acid oxidases (deaminating):ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components:Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain:Predicted transcriptional regulators:Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs:Transcriptional regulator:Predicted phosphohydrolases:DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog:Beta-lactamase class C and other penicillin binding proteins:Uncharacterized conserved protein, contains double-stranded beta-helix domain:Uncharacterized protein conserved in bacteria:Sporulation protein and related proteins:Predicted ring-cleavage extradiol dioxygenase:Predicted O-methyltransferase:ABC-type branched-chain amino acid transport system, permease component:Uncharacterized protein conserved in bacteria:Spore germination protein:Cell cycle control, cell division, chromosome partitioning:Amino acid transport and metabolism:Carbohydrate transport and metabolism:Transcription:Replication, recombination and repair:Posttranslational modification, protein turnover, chaperones:Inorganic ion transport and metabolism:Phenylalanine metabolism:Metabolic pathways:Biosynthesis of secondary metabolites:ABC transporters:RNA polymerase:General function prediction only:Function unknown:Signal transduction mechanisms:excise:SpoIID_LytB:spo_yunB:sigma70-ECF:Defense mechanisms:Membrane Transport:Environmental Information Processing:Transcription:Genetic Information Processing:Cellular processes:Amino Acid Metabolism:Metabolism:Sporulation and germination:Poorly characterized:Metabolism:Cellular processes and signaling:Information storage and processing:Unknown function:General:Metabolism:Global" 450 "5,10-methylene-tetrahydrofolate dehydrogenase/Methenyl tetrahydrofolate cyclohydrolase:Dihydrodipicolinate reductase:Ketopantoate hydroxymethyltransferase:Panthothenate synthetase:Glycosyltransferase:Superfamily II DNA and RNA helicases:DNA polymerase III, alpha subunit:tRNA nucleotidyltransferase/poly(A) polymerase:MoxR-like ATPases:Transcription termination factor:Predicted transcriptional regulators:Aspartate 1-decarboxylase:Predicted phosphohydrolases:Uncharacterized conserved protein:Predicted pyrophosphatase:Methylglyoxal synthase:Ketopantoate reductase:Uncharacterized proteins, LmbE homologs:Replication initiation/membrane attachment protein:Nitric oxide reductase activation protein:Uncharacterized protein conserved in bacteria:Amino acid transport and metabolism:Carbohydrate transport and metabolism:Coenzyme transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:Replication, recombination and repair:Cell wall/membrane/envelope biogenesis:Inorganic ion transport and metabolism:Purine metabolism:Pyrimidine metabolism:Lysine biosynthesis:beta-Alanine metabolism:Pyruvate metabolism:One carbon pool by folate:Carbon fixation pathways in prokaryotes:Pantothenate and CoA biosynthesis:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:RNA degradation:DNA replication:Mismatch repair:Homologous recombination:General function prediction only:Function unknown:panC:dapB:TIGR00159:MGSA:panB:panD:polc:recQ_fam:apbA_panE:nusB:thiol_BshA:thiol_BshB1:Cellular processes and signaling:Carbohydrate Metabolism:Energy Metabolism:Nucleotide Metabolism:Amino Acid Metabolism:Metabolism of Other Amino Acids:Metabolism of Cofactors and Vitamins:Genetic Information Processing:Folding Sorting and Degradation:Replication and Repair:Global:Metabolism:Energy metabolism:Other:DNA metabolism:DNA replication, recombination, and repair:Transcription:Transcription factors:Hypothetical proteins:Conserved:Amino acid biosynthesis:Aspartate family:Biosynthesis of cofactors, prosthetic groups, and carriers:Pantothenate and coenzyme A:Glutathione and analogs:Information storage and processing:Metabolism:Metabolism:Poorly characterized" 451 "Chorismate synthase:Serine/threonine protein kinase:Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily):Serine/threonine protein phosphatase:MoxR-like ATPases:Transcription termination factor:dTDP-D-glucose 4,6-dehydratase:Deoxyxylulose-5-phosphate synthase:GTPase:Exonuclease VII, large subunit:Uncharacterized conserved protein:DNA segregation ATPase FtsK/SpoIIIE and related proteins:Exonuclease VII small subunit:Predicted esterase of the alpha-beta hydrolase superfamily:dTDP-4-dehydrorhamnose 3,5-epimerase and related enzymes:Predicted secreted protein containing a PDZ domain:Nitric oxide reductase activation protein:Uncharacterized protein conserved in bacteria:Cell cycle control, cell division, chromosome partitioning:Amino acid transport and metabolism:Coenzyme transport and metabolism:Lipid transport and metabolism:Transcription:Replication, recombination and repair:Cell wall/membrane/envelope biogenesis:Inorganic ion transport and metabolism:Ubiquinone and other terpenoid-quinone biosynthesis:Phenylalanine tyrosine and tryptophan biosynthesis:Streptomycin biosynthesis:Polyketide sugar unit biosynthesis:Terpenoid backbone biosynthesis:Metabolic pathways:Biosynthesis of secondary metabolites:Mismatch repair:General function prediction only:Function unknown:Signal transduction mechanisms:aroC:TIGR00159:dxs:xseA:dTDP_gluc_dehyt:rmlC:xseB:nusB:menH_SHCHC:Menaquinone and ubiquinone:Biosynthesis of cofactors, prosthetic groups, and carriers:Aromatic amino acid family:Amino acid biosynthesis:Conserved:Hypothetical proteins:Transcription factors:Transcription:Degradation of DNA:DNA metabolism:Metabolism:Metabolism:Global:Replication and Repair:Genetic Information Processing:Biosynthesis of Other Secondary Metabolites:Metabolism of Terpenoids and Polyketides:Metabolism of Cofactors and Vitamins:Information storage and processing:Amino Acid Metabolism:Cellular processes and signaling:Metabolism:Poorly characterized:Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides:Cell envelope:Thiamine" 452 "Uncharacterized conserved protein:Function unknown:spore_sspO:Cellular processes:Sporulation and germination:Poorly characterized" 453 "Energy production and conversion:Aspartate-semialdehyde dehydrogenase:Methionyl-tRNA synthetase:Acetyltransferases:Glycosyltransferases involved in cell wall biogenesis:Zn-dependent hydrolases, including glyoxylases:SAM-dependent methyltransferases:Predicted oxidoreductases (related to aryl-alcohol dehydrogenases):Putative intracellular protease/amidase:5'-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases:ABC-type antimicrobial peptide transport system, ATPase component:Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs:Uncharacterized low-complexity proteins:Acetyltransferases, including N-acetylases of ribosomal proteins:Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain:1-aminocyclopropane-1-carboxylate deaminase:Predicted membrane protein:Uncharacterized conserved protein:Uncharacterized protein conserved in bacteria:Amino acid transport and metabolism:Nucleotide transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:Cell wall/membrane/envelope biogenesis:Purine metabolism:Pyrimidine metabolism:Glycine serine and threonine metabolism:Cysteine and methionine metabolism:Lysine biosynthesis:Tyrosine metabolism:Benzoate degradation:Selenocompound metabolism:Naphthalene degradation:Aminobenzoate degradation:Ethylbenzene degradation:Limonene and pinene degradation:Aminoacyl-tRNA biosynthesis:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:Two-component system:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:Function unknown:Signal transduction mechanisms:metG:ACC_deam_rel:asd_B:thiol_BshC:Defense mechanisms:Metabolism:Poorly characterized:Metabolism:Cellular processes and signaling:Information storage and processing:Glutathione and analogs:Biosynthesis of cofactors, prosthetic groups, and carriers:Aspartate family:Amino acid biosynthesis:tRNA aminoacylation:Protein synthesis:Metabolism:Global:Signal Transduction:Environmental Information Processing:Translation:Genetic Information Processing:Xenobiotics Biodegradation and Metabolism:Metabolism of Terpenoids and Polyketides:Metabolism of Other Amino Acids:Amino Acid Metabolism:Nucleotide Metabolism" 454 "Ribonuclease HI:Ca2+/H+ antiporter:Universal stress protein UspA and related nucleotide-binding proteins:cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases:Predicted transcriptional regulators:ABC-type multidrug transport system, ATPase component:ABC-type sugar transport systems, permease components:Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific:Predicted transcriptional regulators:Uncharacterized protein conserved in bacteria:Metal-dependent hydrolase:Uncharacterized protein conserved in bacteria:Carbohydrate transport and metabolism:Transcription:Replication, recombination and repair:Inorganic ion transport and metabolism:Glycolysis / Gluconeogenesis:Starch and sucrose metabolism:Amino sugar and nucleotide sugar metabolism:ABC transporters:Phosphotransferase system (PTS):DNA replication:General function prediction only:Function unknown:Signal transduction mechanisms:cax:EIIB_glc:Defense mechanisms:Poorly characterized:Carbohydrate Metabolism:Genetic Information Processing:Replication and Repair:Environmental Information Processing:Membrane Transport:Transport and binding proteins:Cations and iron carrying compounds:Signal transduction:PTS:Information storage and processing:Cellular processes and signaling:Metabolism:Metabolism" 455 "Energy production and conversion:Fe-S oxidoreductase:FOG: CBS domain:Topoisomerase IA:Predicted permease:Signal transduction histidine kinase:Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, alpha subunit:Bacterial cell division membrane protein:Lactate dehydrogenase and related dehydrogenases:Phosphomannomutase:Uncharacterized conserved protein containing a ferredoxin-like domain:Metal-dependent amidase/aminoacylase/carboxypeptidase:Transcriptional regulators:Uncharacterized conserved protein:1,4-dihydroxy-2-naphthoate octaprenyltransferase:Acetyltransferases, including N-acetylases of ribosomal proteins:Uncharacterized protein conserved in bacteria:Transcriptional regulators:Uncharacterized protein conserved in bacteria:Predicted membrane protein:Predicted membrane protein:Uncharacterized protein conserved in bacteria:Spore germination protein:Cell cycle control, cell division, chromosome partitioning:Carbohydrate transport and metabolism:Coenzyme transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:Replication, recombination and repair:Citrate cycle (TCA cycle):Pentose phosphate pathway:Ubiquinone and other terpenoid-quinone biosynthesis:Purine metabolism:Arginine and proline metabolism:Amino sugar and nucleotide sugar metabolism:Carbon fixation pathways in prokaryotes:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:General function prediction only:Function unknown:Signal transduction mechanisms:TIGR00273:menA:topB:glmM:amidohydrolases:spore_ytvI:OAFO_sf:Menaquinone and ubiquinone:Carbohydrate Metabolism:Energy Metabolism:Nucleotide Metabolism:Amino Acid Metabolism:Metabolism of Cofactors and Vitamins:Global:Metabolism:Central intermediary metabolism:Amino sugars:Energy metabolism:Electron transport:DNA metabolism:DNA replication, recombination, and repair:Protein fate:Degradation of proteins, peptides, and glycopeptides:Cellular processes:Sporulation and germination:Biosynthesis of cofactors, prosthetic groups, and carriers:Metabolism:Information storage and processing:Cellular processes and signaling:Metabolism:Poorly characterized" 456 "Phosphate uptake regulator:Nucleoside phosphorylase:Predicted transcriptional regulators:Phosphatidylserine/phosphatidylglycerophosphate/cardiolipin synthases and related enzymes:Uncharacterized proteins, homologs of microcin C7 resistance protein MccF:Uncharacterized conserved protein:Acetyltransferases, including N-acetylases of ribosomal proteins:Arabinose efflux permease:UV damage repair endonuclease:Nucleotide transport and metabolism:Carbohydrate transport and metabolism:Lipid transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:Replication, recombination and repair:Inorganic ion transport and metabolism:Cysteine and methionine metabolism:Glycerophospholipid metabolism:Metabolic pathways:Function unknown:uvde:MTA/SAH-Nsdase:phoU_full:Defense mechanisms:Metabolism:Lipid Metabolism:Amino Acid Metabolism:Global:Metabolism:Purines, pyrimidines, nucleosides, and nucleotides:Salvage of nucleosides and nucleotides:DNA metabolism:DNA replication, recombination, and repair:Transport and binding proteins:Anions:Information storage and processing:Cellular processes and signaling:Metabolism:Poorly characterized" 457 "Excinuclease ATPase subunit:Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), B subunit:Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), A subunit:Nucleotidyltransferase/DNA polymerase involved in DNA repair:RecA/RadA recombinase:Helicase subunit of the DNA excision repair complex:ATP-dependent exoDNAse (exonuclease V) beta subunit (contains helicase and exonuclease domains):ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components:Uncharacterized low-complexity proteins:Uncharacterized metal-binding protein:Uncharacterized protein conserved in bacteria:Uncharacterized conserved protein:Uncharacterized protein conserved in bacteria:ATP-dependent nuclease, subunit B:Uncharacterized protein conserved in bacteria:Superfamily I DNA and RNA helicases:Transcriptional regulator, effector-binding domain/component:Coenzyme transport and metabolism:Transcription:Replication, recombination and repair:Inorganic ion transport and metabolism:Histidine metabolism:Tyrosine metabolism:Selenocompound metabolism:Polycyclic aromatic hydrocarbon degradation:Microbial metabolism in diverse environments:Nucleotide excision repair:Mismatch repair:Homologous recombination:General function prediction only:Function unknown:Signal transduction mechanisms:uvra:uvrb:parE_Gpos:parC_Gpos:tigrfam_recA:addB_Gpos:addA_Gpos:Cellular processes and signaling:Information storage and processing:DNA replication, recombination, and repair:DNA metabolism:Metabolism:Metabolism:Global:Replication and Repair:Genetic Information Processing:Xenobiotics Biodegradation and Metabolism:Metabolism of Other Amino Acids:Poorly characterized:Amino Acid Metabolism:Metabolism" 458 "Energy production and conversion:Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis:Glycosyltransferase:Biotin carboxylase:Nucleoside-diphosphate-sugar epimerases:Uridine kinase:Membrane-associated phospholipid phosphatase:Spermidine/putrescine-binding periplasmic protein:Bacterial cell division membrane protein:Collagenase and related proteases:Rad3-related DNA helicases:Predicted glycosyltransferases:Na+/H+-dicarboxylate symporters:Deoxynucleoside kinases:Uncharacterized conserved protein:Sugar transferases involved in lipopolysaccharide synthesis:Signal transduction histidine kinase:Cell cycle control, cell division, chromosome partitioning:Amino acid transport and metabolism:Nucleotide transport and metabolism:Carbohydrate transport and metabolism:Lipid transport and metabolism:Transcription:Replication, recombination and repair:Cell wall/membrane/envelope biogenesis:Posttranslational modification, protein turnover, chaperones:Fructose and mannose metabolism:Purine metabolism:Pyrimidine metabolism:Metabolic pathways:ABC transporters:General function prediction only:Function unknown:Signal transduction mechanisms:sensory_box:udk:tRNA_RlmH_YbeA:ftsW:Membrane Transport:Environmental Information Processing:Nucleotide Metabolism:Cell division:Carbohydrate Metabolism:Information storage and processing:Cellular processes and signaling:Metabolism:Poorly characterized:Metabolism:Cellular processes:tRNA and rRNA base modification:Protein synthesis:Small molecule interactions:Regulatory functions:Salvage of nucleosides and nucleotides:Purines, pyrimidines, nucleosides, and nucleotides:Metabolism:Global" 459 "Energy production and conversion:Citrate synthase:Amino acid transporters:PEP phosphonomutase and related enzymes:Predicted membrane protein:Uncharacterized conserved protein:Amino acid transport and metabolism:Carbohydrate transport and metabolism:Citrate cycle (TCA cycle):Glyoxylate and dicarboxylate metabolism:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:Function unknown:prpB:spore_SleB:spore_YpeB:spore_YhcN_YlaJ:Cellular processes:Carbohydrate Metabolism:Global:Metabolism:Metabolism:Sporulation and germination:Metabolism:Poorly characterized" 460 "Energy production and conversion:Acetyltransferases:Zn-dependent hydrolases, including glyoxylases:Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily):Signal transduction histidine kinase:2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases:Na+-dependent transporters of the SNF family:Methyl-accepting chemotaxis protein:Predicted nucleoside-diphosphate sugar epimerases:Phosphomannomutase:UDP-glucose pyrophosphorylase:Predicted branched-chain amino acid permease (azaleucine resistance):Predicted transcriptional regulators:Transcriptional regulator:Allophanate hydrolase subunit 1:Uncharacterized FAD-dependent dehydrogenases:Predicted esterase of the alpha-beta hydrolase superfamily:Amino acid transport and metabolism:Carbohydrate transport and metabolism:Coenzyme transport and metabolism:Transcription:Cell wall/membrane/envelope biogenesis:Cell motility:Pentose and glucuronate interconversions:Fructose and mannose metabolism:Galactose metabolism:Arginine and proline metabolism:Tyrosine metabolism:Benzoate degradation:Starch and sucrose metabolism:Amino sugar and nucleotide sugar metabolism:Naphthalene degradation:Aminobenzoate degradation:Ethylbenzene degradation:Limonene and pinene degradation:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:Two-component system:Bacterial chemotaxis:General function prediction only:Signal transduction mechanisms:TIGR00370:galU:Conserved:Carbohydrate Metabolism:Amino Acid Metabolism:Metabolism of Terpenoids and Polyketides:Xenobiotics Biodegradation and Metabolism:Environmental Information Processing:Signal Transduction:Cellular Processes:Cell Motility:Global:Metabolism:Hypothetical proteins:Metabolism:Cell envelope:Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides:Information storage and processing:Cellular processes and signaling:Metabolism:Poorly characterized" 461 "Energy production and conversion:Argininosuccinate lyase:FAD/FMN-containing dehydrogenases:Predicted amidohydrolase:F0F1-type ATP synthase, subunit b:Predicted xylanase/chitin deacetylase:Subtilisin-like serine proteases:Predicted membrane protein:ABC-type Na+ efflux pump, permease component:ABC-type polysaccharide/polyol phosphate export systems, permease component:D-alanyl-D-alanine carboxypeptidase:Uncharacterized conserved protein:Predicted transcriptional regulator:Sortase (surface protein transpeptidase):ABC-type uncharacterized transport system, ATPase component:Amino acid transport and metabolism:Carbohydrate transport and metabolism:Transcription:Cell wall/membrane/envelope biogenesis:Posttranslational modification, protein turnover, chaperones:Inorganic ion transport and metabolism:Alanine aspartate and glutamate metabolism:Arginine and proline metabolism:Peptidoglycan biosynthesis:Glyoxylate and dicarboxylate metabolism:Nitrogen metabolism:Metabolic pathways:Biosynthesis of secondary metabolites:ABC transporters:General function prediction only:Function unknown:PduO_Nterm:argH:sortase_fam:pip_yhgE_Nterm:Glutamate family:Amino acid biosynthesis:Protein and peptide secretion and trafficking:Protein fate:Metabolism:Global:Metabolism:Membrane Transport:Environmental Information Processing:Glycan Biosynthesis and Metabolism:Amino Acid Metabolism:Energy Metabolism:Metabolism:Carbohydrate Metabolism:Poorly characterized:Cellular processes and signaling:Information storage and processing:Heme, porphyrin, and cobalamin:Biosynthesis of cofactors, prosthetic groups, and carriers" 462 "Energy production and conversion:Pseudouridylate synthase:FAD/FMN-containing dehydrogenases:Superfamily II DNA and RNA helicases:Translation initiation factor 2 (IF-2; GTPase):Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily):2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases:Methyl-accepting chemotaxis protein:N-acetylmuramoyl-L-alanine amidase:Non-ribosomal peptide synthetase modules and related proteins:ADP-ribose pyrophosphatase:ABC-type multidrug transport system, ATPase and permease components:Chromosome segregation ATPases:Choline-glycine betaine transporter:Uncharacterized protein conserved in bacteria:Signal transduction histidine kinase regulating citrate/malate metabolism:Uncharacterized protein conserved in bacteria:Flagellar basal body rod protein:Cell cycle control, cell division, chromosome partitioning:Nucleotide transport and metabolism:Coenzyme transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:Replication, recombination and repair:Cell wall/membrane/envelope biogenesis:Cell motility:Two-component system:Bacterial chemotaxis:Flagellar assembly:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:Function unknown:Signal transduction mechanisms:hisT_truA:small_GTP:DegV:AA-adenyl-dom:SMC_prok_B:spore_cwlD:FlgEFG_subfam:Defense mechanisms:Signal Transduction:Poorly characterized:Cellular processes and signaling:Information storage and processing:Environmental Information Processing:General:Unknown function:Sporulation and germination:Cellular processes:tRNA and rRNA base modification:Protein synthesis:Chromosome-associated proteins:DNA metabolism:Cell Motility:Cellular Processes:Metabolism" 463 "3-isopropylmalate dehydratase large subunit:Nucleoside-diphosphate-sugar epimerases:Glycine/D-amino acid oxidases (deaminating):dTDP-D-glucose 4,6-dehydratase:Myo-inositol-1-phosphate synthase:Transcriptional regulator, contains sigma factor-related N-terminal domain:Cephalosporin hydroxylase:Uncharacterized membrane protein:Phage-related protein:Amino acid transport and metabolism:Carbohydrate transport and metabolism:Lipid transport and metabolism:Transcription:Cell wall/membrane/envelope biogenesis:Glycine serine and threonine metabolism:Valine leucine and isoleucine biosynthesis:Amino sugar and nucleotide sugar metabolism:Streptomycin biosynthesis:Inositol phosphate metabolism:C5-Branched dibasic acid metabolism:Metabolic pathways:Biosynthesis of secondary metabolites:Function unknown:leuC:phi3626_gp14_N:phage_arpU:CDP_4_6_dhtase:Defense mechanisms:Metabolism:Carbohydrate Metabolism:Amino Acid Metabolism:Biosynthesis of Other Secondary Metabolites:Global:Metabolism:Regulatory functions:DNA interactions:Mobile and extrachromosomal element functions:Prophage functions:Amino acid biosynthesis:Pyruvate family:Cell envelope:Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides:Information storage and processing:Cellular processes and signaling:Metabolism:Poorly characterized" 464 "Ornithine carbamoyltransferase:4-aminobutyrate aminotransferase and related aminotransferases:Uncharacterized conserved protein:Enoyl-CoA hydratase/carnithine racemase:Flagellin and related hook-associated proteins:Arginine deiminase:FOG: PKD repeat:Uncharacterized protein conserved in bacteria:Predicted choloylglycine hydrolase:Amino acid transport and metabolism:Lipid transport and metabolism:Cell motility:Fatty acid metabolism:Alanine aspartate and glutamate metabolism:Valine leucine and isoleucine degradation:Geraniol degradation:Lysine degradation:Arginine and proline metabolism:Benzoate degradation:Tryptophan metabolism:beta-Alanine metabolism:Aminobenzoate degradation:Propanoate metabolism:Butanoate metabolism:Limonene and pinene degradation:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:Two-component system:Flagellar assembly:General function prediction only:Function unknown:orni_carb_tr:GABAtrnsam:arcA:DnaD_dom:WXG100_ESAT6:Other:Carbohydrate Metabolism:Lipid Metabolism:Amino Acid Metabolism:Metabolism of Other Amino Acids:Metabolism of Terpenoids and Polyketides:Xenobiotics Biodegradation and Metabolism:Environmental Information Processing:Signal Transduction:Cellular Processes:Cell Motility:Global:Metabolism:Central intermediary metabolism:Metabolism:Energy metabolism:Amino acids and amines:Mobile and extrachromosomal element functions:Prophage functions:Amino acid biosynthesis:Glutamate family:Cellular processes and signaling:Metabolism:Poorly characterized" 465 "Energy production and conversion:Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II:Uncharacterized conserved protein:NADPH:quinone reductase and related Zn-dependent oxidoreductases:Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs:Lysine efflux permease:Transcriptional regulator:Arabinose efflux permease:SH3 domain protein:Signal transduction histidine kinase regulating phosphoglycerate transport system:Signal transduction histidine kinase:Amino acid transport and metabolism:Carbohydrate transport and metabolism:Lipid transport and metabolism:Transcription:Ubiquinone and other terpenoid-quinone biosynthesis:Metabolic pathways:Biosynthesis of secondary metabolites:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:Function unknown:Signal transduction mechanisms:lytR_cpsA_psr:efflux_Bcr_CflA:menE:Global:Cellular processes and signaling:Metabolism of Cofactors and Vitamins:Metabolism:Poorly characterized:Metabolism:Information storage and processing:Menaquinone and ubiquinone:Biosynthesis of cofactors, prosthetic groups, and carriers:Other:Regulatory functions:Metabolism" 466 "Predicted hydrolase of the metallo-beta-lactamase superfamily:Holliday junction resolvasome, DNA-binding subunit:Predicted phosphatase/phosphohexomutase:Preprotein translocase subunit SecE:Ribonuclease HIII:A/G-specific DNA glycosylase:Uncharacterized membrane protein, required for colicin V production:Mn-dependent transcriptional regulator:Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily:Large-conductance mechanosensitive channel:Uncharacterized protein conserved in bacteria:Predicted permease, DMT superfamily:Predicted small secreted protein:Transcription:Replication, recombination and repair:Cell wall/membrane/envelope biogenesis:RNA degradation:DNA replication:Protein export:Bacterial secretion system:Base excision repair:Homologous recombination:General function prediction only:Function unknown:ruvA:mscL:MG423:rnhC:secE_bact:mutY:HAD-SF-IA-v3:Intracellular trafficking, secretion, and vesicular transport:Hypothetical proteins:Adaptations to atypical conditions:Cellular processes:Protein and peptide secretion and trafficking:Protein fate:DNA replication, recombination, and repair:DNA metabolism:Genetic Information Processing:Membrane Transport:Environmental Information Processing:Replication and Repair:Unknown function:Folding Sorting and Degradation:Enzymes of unknown specificity:Information storage and processing:Cellular processes and signaling:Poorly characterized:Conserved" 467 "Energy production and conversion:Uncharacterized conserved protein:N-formylmethionyl-tRNA deformylase:Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II:Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily):ABC-type nitrate/sulfonate/bicarbonate transport system, permease component:ABC-type Fe3+-siderophore transport system, permease component:ABC-type Fe3+-hydroxamate transport system, periplasmic component:ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components:Predicted sulfurtransferase:ABC-type multidrug transport system, ATPase and permease components:2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase:Isochorismate synthase:Primosomal protein N' (replication factor Y) - superfamily II helicase:Na+/H+-dicarboxylate symporters:Uncharacterized protein conserved in bacteria:Type II secretory pathway, prepilin signal peptidase PulO and related peptidases:ABC-type uncharacterized transport system, permease component:ABC-type uncharacterized transport system, ATPase component:ABC-type uncharacterized transport system, permease component:Coenzyme transport and metabolism:Lipid transport and metabolism:Translation, ribosomal structure and biogenesis:Replication, recombination and repair:Cell motility:Posttranslational modification, protein turnover, chaperones:Inorganic ion transport and metabolism:Ubiquinone and other terpenoid-quinone biosynthesis:Biosynthesis of siderophore group nonribosomal peptides:Metabolic pathways:Biosynthesis of secondary metabolites:ABC transporters:Homologous recombination:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:Function unknown:TIGR00046:pept_deformyl:TIGR00106:menD:isochor_syn:priA:menE:menH_SHCHC:Intracellular trafficking, secretion, and vesicular transport:Defense mechanisms:Cellular processes and signaling:Metabolism of Cofactors and Vitamins:Metabolism of Terpenoids and Polyketides:Genetic Information Processing:Replication and Repair:Environmental Information Processing:Membrane Transport:Global:Metabolism:DNA metabolism:DNA replication, recombination, and repair:Protein synthesis:tRNA and rRNA base modification:Protein fate:Protein modification and repair:Unknown function:General:Biosynthesis of cofactors, prosthetic groups, and carriers:Menaquinone and ubiquinone:Information storage and processing:Metabolism:Metabolism:Poorly characterized" 468 "Energy production and conversion:ABC-type cobalt transport system, permease component CbiQ and related transporters:16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases:Cytochrome bd-type quinol oxidase, subunit 2:Sugar phosphate permease:Arabinose efflux permease:H+/citrate symporter:DNA gyrase inhibitor:Phospholipid N-methyltransferase:Predicted permease, cadmium resistance protein:Carbohydrate transport and metabolism:Lipid transport and metabolism:Translation, ribosomal structure and biogenesis:Replication, recombination and repair:Inorganic ion transport and metabolism:Oxidative phosphorylation:Bisphenol degradation:Aminobenzoate degradation:Metabolic pathways:Microbial metabolism in diverse environments:ABC transporters:TIGR00093:citMHS:DNA_bind_RsfA:ocin_ThiF_like:Metabolism:Energy Metabolism:Xenobiotics Biodegradation and Metabolism:Environmental Information Processing:Membrane Transport:Global:Metabolism:Protein synthesis:tRNA and rRNA base modification:Transport and binding proteins:Carbohydrates, organic alcohols, and acids:Cellular processes:Toxin production and resistance:Sporulation and germination:Information storage and processing:Metabolism" 469 "Serine-pyruvate aminotransferase/archaeal aspartate aminotransferase:Transcriptional regulator:ABC-type multidrug transport system, permease component:ABC-type multidrug transport system, ATPase component:ABC-type Fe3+ transport system, permease component:3-hydroxyacyl-CoA dehydrogenase:Beta-lactamase class C and other penicillin binding proteins:Saccharopine dehydrogenase and related proteins:ABC-type Fe3+ transport system, periplasmic component:Acyl-CoA dehydrogenases:Protein related to penicillin acylase:ABC-type spermidine/putrescine transport systems, ATPase components:Amino acid transport and metabolism:Lipid transport and metabolism:Transcription:Inorganic ion transport and metabolism:Geraniol degradation:Penicillin and cephalosporin biosynthesis:Benzoate degradation:Phosphonate and phosphinate metabolism:Naphthalene degradation:Butanoate metabolism:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:ABC transporters:General function prediction only:transamin_PhnW:Defense mechanisms:Metabolism:Metabolism:Global:Membrane Transport:Environmental Information Processing:Xenobiotics Biodegradation and Metabolism:Biosynthesis of Other Secondary Metabolites:Metabolism of Terpenoids and Polyketides:Metabolism of Other Amino Acids:Information storage and processing:Carbohydrate Metabolism:Cellular processes and signaling:Metabolism:Poorly characterized:Phosphorus compounds:Central intermediary metabolism" 470 "Molecular chaperone (small heat shock protein):Uncharacterized conserved protein:Posttranslational modification, protein turnover, chaperones:Function unknown:spore_ytfJ:SASP_tlp:SASP_sspI:Cellular processes and signaling:Poorly characterized:Sporulation and germination:Cellular processes" 471 "Glutamyl- and glutaminyl-tRNA synthetases:Undecaprenyl pyrophosphate synthase:Guanylate kinase:Protein chain release factor A:Ribosome recycling factor:Translation elongation factor Ts:Phosphate/sulphate permeases:Aspartate/tyrosine/aromatic aminotransferase:Dihydroxynaphthoic acid synthase:Phosphoribosylpyrophosphate synthetase:Pyruvate kinase:Uridylate kinase:Phosphoenolpyruvate-protein kinase (PTS system EI component in bacteria):Lysyl-tRNA synthetase (class II):Amino acid transport and metabolism:Nucleotide transport and metabolism:Carbohydrate transport and metabolism:Coenzyme transport and metabolism:Lipid transport and metabolism:Translation, ribosomal structure and biogenesis:Inorganic ion transport and metabolism:Glycolysis / Gluconeogenesis:Pentose phosphate pathway:Ubiquinone and other terpenoid-quinone biosynthesis:Purine metabolism:Pyrimidine metabolism:Alanine aspartate and glutamate metabolism:Cysteine and methionine metabolism:Arginine and proline metabolism:Tyrosine metabolism:Phenylalanine metabolism:Phenylalanine tyrosine and tryptophan biosynthesis:Novobiocin biosynthesis:Pyruvate metabolism:Terpenoid backbone biosynthesis:Aminoacyl-tRNA biosynthesis:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:Phosphotransferase system (PTS):prfA:uppS:tsf:gltX_bact:frr:lysS_bact:pyruv_kin:ribP_PPkin:PTS_I_fam:menB:pyrH_bact:guanyl_kin:Membrane Transport:Environmental Information Processing:Translation:Genetic Information Processing:Biosynthesis of Other Secondary Metabolites:Metabolism:Metabolism of Terpenoids and Polyketides:Metabolism of Cofactors and Vitamins:Amino Acid Metabolism:Nucleotide Metabolism:Carbohydrate Metabolism:Energy metabolism:Glycolysis/gluconeogenesis:Purines, pyrimidines, nucleosides, and nucleotides:Nucleotide and nucleoside interconversions:Purine ribonucleotide biosynthesis:Protein synthesis:tRNA aminoacylation:Translation factors:Biosynthesis of cofactors, prosthetic groups, and carriers:Menaquinone and ubiquinone:Cell envelope:Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides:Information storage and processing:Metabolism:Metabolism:Global" 472 "Acetyltransferases:D-alanyl-D-alanine carboxypeptidase:Arylamine N-acetyltransferase:Uncharacterized conserved protein:Response regulator of citrate/malate metabolism:Phage-related holin (Lysis protein):Transcriptional regulator, effector-binding domain/component:Transcription:Cell wall/membrane/envelope biogenesis:Peptidoglycan biosynthesis:Metabolic pathways:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:Function unknown:Signal transduction mechanisms:holin_tox_secr:spore_yhbH:Metabolism:Glycan Biosynthesis and Metabolism:Global:Metabolism:Cellular processes:Sporulation and germination:Mobile and extrachromosomal element functions:Prophage functions:Information storage and processing:Cellular processes and signaling:Metabolism:Poorly characterized" 473 "Energy production and conversion:Fe-S oxidoreductase:Proline dehydrogenase:Amino acid transporters:Branched-chain amino acid permeases:Predicted redox protein, regulator of disulfide bond formation:Predicted ATPase related to phosphate starvation-inducible protein PhoH:Dipeptide/tripeptide permease:Response regulator of the LytR/AlgR family:ABC-type oligopeptide transport system, periplasmic component:Amino acid transport and metabolism:Transcription:Posttranslational modification, protein turnover, chaperones:Arginine and proline metabolism:Histidine metabolism:Tyrosine metabolism:Selenocompound metabolism:Polycyclic aromatic hydrocarbon degradation:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:ABC transporters:Signal transduction mechanisms:livcs:yjdL_sub1_fam:Transport and binding proteins:Amino Acid Metabolism:Metabolism of Other Amino Acids:Xenobiotics Biodegradation and Metabolism:Environmental Information Processing:Membrane Transport:Global:Metabolism:Metabolism:Amino acids, peptides and amines:Information storage and processing:Cellular processes and signaling:Metabolism" 474 "Xaa-Pro aminopeptidase:Transketolase:Isoleucyl-tRNA synthetase:Aspartyl-tRNA synthetase:Thymidylate synthase:Protein chain release factor A:Short-chain dehydrogenases of various substrate specificities:Dihydrodipicolinate synthase/N-acetylneuraminate lyase:Asparagine synthase (glutamine-hydrolyzing):Pseudouridylate synthases, 23S RNA-specific:Predicted hydrolase of the metallo-beta-lactamase superfamily:Predicted Fe-S-cluster redox enzyme:Cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes:Predicted membrane protein involved in D-alanine export:Transcriptional regulators:Uncharacterized protein with SCP/PR1 domains:Amino acid transport and metabolism:Nucleotide transport and metabolism:Carbohydrate transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:Cell wall/membrane/envelope biogenesis:Pentose phosphate pathway:Pyrimidine metabolism:Alanine aspartate and glutamate metabolism:Valine leucine and isoleucine biosynthesis:Lysine biosynthesis:One carbon pool by folate:Thiamine metabolism:Nitrogen metabolism:Aminoacyl-tRNA biosynthesis:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:RNA degradation:Sulfur relay system:General function prediction only:Function unknown:rluA_subfam:prfB:TIGR00048:tktlase_bact:ileS:aspS_bact:MG423:dapA:asn_synth_AEB:spore_YkwD:thym_sym:LTA_dltB:Biosynthesis and degradation of murein sacculus and peptidoglycan:Information storage and processing:Cellular processes and signaling:Metabolism:Poorly characterized:Metabolism:Global:Metabolism:Folding Sorting and Degradation:Translation:Genetic Information Processing:Metabolism of Cofactors and Vitamins:Amino Acid Metabolism:Nucleotide Metabolism:Energy Metabolism:Carbohydrate Metabolism:Energy metabolism:Pentose phosphate pathway:Purines, pyrimidines, nucleosides, and nucleotides:2'-Deoxyribonucleotide metabolism:Protein synthesis:tRNA aminoacylation:tRNA and rRNA base modification:Translation factors:Hypothetical proteins:Conserved:Amino acid biosynthesis:Aspartate family:Cell envelope" 475 "Energy production and conversion:Purine nucleoside phosphorylase:Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase:Acetyltransferase (isoleucine patch superfamily):Short-chain dehydrogenases of various substrate specificities:ATPase components of ABC transporters with duplicated ATPase domains:ATPases involved in chromosome partitioning:Organic radical activating enzymes:Predicted transcriptional regulators:Phosphopentomutase:Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases):Aconitase A:HD superfamily phosphohydrolases:Cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes:ATPases involved in chromosome partitioning:Uncharacterized conserved protein:Putative effector of murein hydrolase LrgA:Predicted transcriptional regulators:Uncharacterized protein conserved in bacteria:Transcriptional regulators:Cation transport ATPase:Uncharacterized anaerobic dehydrogenase:Uncharacterized protein conserved in bacteria:Cell cycle control, cell division, chromosome partitioning:Amino acid transport and metabolism:Nucleotide transport and metabolism:Carbohydrate transport and metabolism:Lipid transport and metabolism:Transcription:Posttranslational modification, protein turnover, chaperones:Inorganic ion transport and metabolism:Glycolysis / Gluconeogenesis:Citrate cycle (TCA cycle):Pentose phosphate pathway:Purine metabolism:Pyrimidine metabolism:Glyoxylate and dicarboxylate metabolism:Methane metabolism:Carbon fixation pathways in prokaryotes:Thiamine metabolism:Nicotinate and nicotinamide metabolism:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:Two-component system:Sulfur relay system:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:Function unknown:aconitase_1:ATPase_P-type:GAPDH-I:Fdh-alpha:deoB:PNPH-PUNA-XAPA:trehalos_R_Bsub:NrdG:DNA_bind_RsfA:Glycolysis/gluconeogenesis:Energy metabolism:Metabolism:Global:Metabolism:Signal Transduction:Environmental Information Processing:Folding Sorting and Degradation:Genetic Information Processing:Metabolism of Cofactors and Vitamins:Nucleotide Metabolism:Energy Metabolism:Sporulation and germination:Carbohydrate Metabolism:Information storage and processing:Cellular processes and signaling:Metabolism:Poorly characterized:Cellular processes:Protein modification and repair:Protein fate:DNA interactions:Regulatory functions:Other:Purines, pyrimidines, nucleosides, and nucleotides:TCA cycle" 476 "Energy production and conversion:Ribonuclease HII:Transcription elongation factor:tRNA-(guanine-N1)-methyltransferase:Signal recognition particle GTPase:Signal recognition particle GTPase:Organic radical activating enzymes:Predicted PP-loop superfamily ATPase:6-pyruvoyl-tetrahydropterin synthase:Predicted xylanase/chitin deacetylase:RimM protein, required for 16S rRNA processing:Nicotinic acid mononucleotide adenylyltransferase:Ribosomal protein HS6-type (S12/L30/L7a):Uncharacterized protein conserved in bacteria:Uncharacterized Fe-S protein:Predicted HD superfamily hydrolase involved in NAD metabolism:Uncharacterized protein conserved in bacteria:Predicted nucleic-acid-binding protein implicated in transcription termination:Predicted membrane protein:Carbohydrate transport and metabolism:Coenzyme transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:Replication, recombination and repair:Posttranslational modification, protein turnover, chaperones:Nicotinate and nicotinamide metabolism:Folate biosynthesis:Metabolic pathways:DNA replication:Protein export:Bacterial secretion system:General function prediction only:Function unknown:TIGR00046:ftsY:trmD:cyt_tran_rel:TIGR00276:HDIG:TIGR00364:ffh:NusA:16S_RimM:spore_ylxY:Bsubt_queE:queuosine_QueD:Intracellular trafficking, secretion, and vesicular transport:Metabolism:Cellular processes and signaling:Information storage and processing:General:Unknown function:Sporulation and germination:Cellular processes:Protein and peptide secretion and trafficking:Protein fate:tRNA and rRNA base modification:Protein synthesis:RNA processing:Transcription factors:Transcription:Electron transport:Energy metabolism:Metabolism:Metabolism:Global:Membrane Transport:Environmental Information Processing:Replication and Repair:Folding Sorting and Degradation:Genetic Information Processing:Poorly characterized:Metabolism of Cofactors and Vitamins" 477 "Energy production and conversion:Malate/lactate dehydrogenases:Lipoate-protein ligase A:Adenylosuccinate synthase:Asparagine synthase (glutamine-hydrolyzing):Glutaredoxin and related proteins:Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities:Predicted membrane GTPase involved in stress response:Cold shock proteins:Uncharacterized conserved protein:Transcriptional regulators:Predicted secreted protein:Uncharacterized conserved protein:Amino acid transport and metabolism:Nucleotide transport and metabolism:Coenzyme transport and metabolism:Transcription:Posttranslational modification, protein turnover, chaperones:Glycolysis / Gluconeogenesis:Purine metabolism:Alanine aspartate and glutamate metabolism:Cysteine and methionine metabolism:Selenocompound metabolism:Pyruvate metabolism:Propanoate metabolism:Nitrogen metabolism:Sulfur metabolism:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:Function unknown:Signal transduction mechanisms:purA:small_GTP:asn_synth_AEB:L-LDH-NAD:GlrX_YruB:TIGR03833:Metabolism:Poorly characterized:Energy metabolism:Metabolism:Global:Metabolism of Other Amino Acids:Amino Acid Metabolism:Nucleotide Metabolism:Metabolism:Energy Metabolism:Glycolysis/gluconeogenesis:Carbohydrate Metabolism:Purines, pyrimidines, nucleosides, and nucleotides:Purine ribonucleotide biosynthesis:Hypothetical proteins:Conserved:Unknown function:General:Amino acid biosynthesis:Aspartate family:Information storage and processing:Cellular processes and signaling" 478 "Dihydrofolate reductase:Putative GTPases (G3E family):Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily):Predicted unusual protein kinase:Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases):Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific:Predicted membrane protein, hemolysin III homolog:Predicted transcriptional regulators:Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase:Beta-fructosidases (levanase/invertase):Uncharacterized protein conserved in bacteria:Uncharacterized protein conserved in bacteria:Signal transduction histidine kinase:Carbohydrate transport and metabolism:Coenzyme transport and metabolism:Lipid transport and metabolism:Transcription:Galactose metabolism:Ubiquinone and other terpenoid-quinone biosynthesis:Starch and sucrose metabolism:One carbon pool by folate:Folate biosynthesis:Metabolic pathways:Biosynthesis of secondary metabolites:Phosphotransferase system (PTS):Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:Function unknown:Signal transduction mechanisms:TIGR00147:EIIB_glc:hlyIII:scrB_fam:Information storage and processing:Carbohydrate Metabolism:Metabolism of Cofactors and Vitamins:Environmental Information Processing:Membrane Transport:Global:Metabolism:Energy metabolism:Biosynthesis and degradation of polysaccharides:Unknown function:Enzymes of unknown specificity:Signal transduction:PTS:Metabolism:Cellular processes and signaling:Metabolism:Poorly characterized" 479 "Spermidine synthase:Peroxiredoxin:Na+/proline symporter:Predicted permease:Predicted xylanase/chitin deacetylase:Na+-dependent transporters of the SNF family:Cell division protein FtsI/penicillin-binding protein 2:DNA-directed RNA polymerase, subunit K/omega:Transcriptional regulators:Teichoic acid biosynthesis proteins:DNA polymerase III, alpha subunit (gram-positive type):Sugar phosphate permease:Predicted membrane protein:Amino acid transport and metabolism:Carbohydrate transport and metabolism:Transcription:Replication, recombination and repair:Cell wall/membrane/envelope biogenesis:Posttranslational modification, protein turnover, chaperones:Purine metabolism:Pyrimidine metabolism:Cysteine and methionine metabolism:Arginine and proline metabolism:beta-Alanine metabolism:Glutathione metabolism:Peptidoglycan biosynthesis:Metabolic pathways:RNA polymerase:DNA replication:Mismatch repair:Homologous recombination:General function prediction only:Function unknown:speE:dnaq:rpoZ:wecG_tagA_cpsF:glpT:caa3_CtaG:spore_ylxY:Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides:Information storage and processing:Cellular processes and signaling:Metabolism:Poorly characterized:Metabolism:Global:Metabolism:Replication and Repair:Transcription:Genetic Information Processing:Glycan Biosynthesis and Metabolism:Metabolism of Other Amino Acids:Amino Acid Metabolism:Central intermediary metabolism:Nucleotide Metabolism:Polyamine biosynthesis:DNA metabolism:Degradation of DNA:Transcription:DNA-dependent RNA polymerase:Transport and binding proteins:Other:Cellular processes:Sporulation and germination:Cell envelope" 480 "Energy production and conversion:Transaldolase:Carbonic anhydrase:Aspartate/tyrosine/aromatic aminotransferase:Signal peptidase I:Bacterial nucleoid DNA-binding protein:NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit:Lactate dehydrogenase and related dehydrogenases:NADH dehydrogenase, FAD-containing subunit:Putative threonine efflux protein:Transcriptional regulator:Uncharacterized protein conserved in bacteria:Amino acid transport and metabolism:Carbohydrate transport and metabolism:Coenzyme transport and metabolism:Transcription:Replication, recombination and repair:Inorganic ion transport and metabolism:Pentose phosphate pathway:Oxidative phosphorylation:Lysine biosynthesis:Nitrogen metabolism:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:Protein export:General function prediction only:Function unknown:fsa_talC_mipB:sigpep_I_bact:Intracellular trafficking, secretion, and vesicular transport:Protein fate:Pentose phosphate pathway:Energy metabolism:Metabolism:Global:Metabolism:Folding Sorting and Degradation:Genetic Information Processing:Amino Acid Metabolism:Energy Metabolism:Poorly characterized:Carbohydrate Metabolism:Metabolism:Cellular processes and signaling:Information storage and processing:Protein and peptide secretion and trafficking" 481 "Energy production and conversion:Ammonia permease:Predicted membrane protein:Kef-type K+ transport systems, membrane components:Predicted phosphatases:Transcriptional regulator:Uncharacterized homolog of gamma-carboxymuconolactone decarboxylase subunit:Predicted dehydrogenases and related proteins:Cytochrome c biogenesis protein:Amino acid permeases:Methyl-accepting chemotaxis protein:Fructose-1-phosphate kinase and related fructose-6-phosphate kinase (PfkB):Cytochrome bd-type quinol oxidase, subunit 1:Uncharacterized bacitracin resistance protein:Cytochrome c, mono- and diheme variants:Chromate transport protein ChrA:Transcriptional regulators:Uncharacterized protein conserved in bacteria:Arabinose efflux permease:ABC-type transport system involved in cytochrome bd biosynthesis, fused ATPase and permease components:Signal transduction histidine kinase:Amino acid transport and metabolism:Carbohydrate transport and metabolism:Transcription:Cell motility:Posttranslational modification, protein turnover, chaperones:Inorganic ion transport and metabolism:Fructose and mannose metabolism:Oxidative phosphorylation:Peptidoglycan biosynthesis:Glyoxylate and dicarboxylate metabolism:Metabolic pathways:ABC transporters:Two-component system:Bacterial chemotaxis:General function prediction only:Function unknown:Signal transduction mechanisms:efflux_EmrB:undec_PP_bacA:amt:2a37:2A51:LPXTG_anchor:HAD-SF-IA-v1:CydC:1-PFK:Defense mechanisms:Poorly characterized:Metabolism:Cellular processes and signaling:Information storage and processing:Biosynthesis and degradation of murein sacculus and peptidoglycan:Other:Cell envelope:Enzymes of unknown specificity:Unknown function:Other:Cations and iron carrying compounds:Anions:Transport and binding proteins:Metabolism:Metabolism:Global:Cell Motility:Cellular Processes:Signal Transduction:Membrane Transport:Environmental Information Processing:Glycan Biosynthesis and Metabolism:Energy Metabolism:Carbohydrate Metabolism" 482 "Energy production and conversion:Pseudouridylate synthase:Geranylgeranyl pyrophosphate synthase:Predicted phosphatases:Prolipoprotein diacylglyceryltransferase:Nitroreductase:Uncharacterized protein conserved in bacteria:Serine kinase of the HPr protein, regulates carbohydrate metabolism:D-alanyl-D-alanine carboxypeptidase:Xanthine/uracil permeases:SH3 domain protein:Predicted membrane protein:Nucleotide transport and metabolism:Coenzyme transport and metabolism:Translation, ribosomal structure and biogenesis:Cell wall/membrane/envelope biogenesis:Oxidative phosphorylation:Terpenoid backbone biosynthesis:Biosynthesis of secondary metabolites:General function prediction only:Function unknown:Signal transduction mechanisms:hisT_truA:lgt:hpr-ser:DegV:HAD-SF-IA-v3:GerC3_HepT:PTS:Energy Metabolism:Metabolism of Terpenoids and Polyketides:Global:Metabolism:Protein synthesis:tRNA and rRNA base modification:Protein fate:Protein modification and repair:Unknown function:Enzymes of unknown specificity:General:Biosynthesis of cofactors, prosthetic groups, and carriers:Menaquinone and ubiquinone:Signal transduction:Metabolism:Information storage and processing:Cellular processes and signaling:Metabolism:Poorly characterized" 483 "Energy production and conversion:Predicted ATPase of the PP-loop superfamily implicated in cell cycle control:Molecular chaperone (small heat shock protein):Peroxiredoxin:ATPases with chaperone activity, ATP-binding subunit:Predicted hydrolases of the HAD superfamily:Phosphoglycerate mutase 1:Protease subunit of ATP-dependent Clp proteases:Nitroreductase:Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases):Predicted ATP-dependent serine protease:Cellulase M and related proteins:Transcriptional regulators:Predicted nucleic-acid-binding protein (contains the HHH domain):Transcriptional regulators:Predicted membrane-bound metal-dependent hydrolases:Predicted oxidoreductase related to nitroreductase:Alkyl hydroperoxide reductase, large subunit:Arginine kinase:Uncharacterized protein with conserved CXXC pairs:Transcriptional repressor of class III stress genes:Cell cycle control, cell division, chromosome partitioning:Amino acid transport and metabolism:Carbohydrate transport and metabolism:Lipid transport and metabolism:Transcription:Posttranslational modification, protein turnover, chaperones:Glycolysis / Gluconeogenesis:Fatty acid biosynthesis:Methane metabolism:Biosynthesis of unsaturated fatty acids:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:Function unknown:Cof-subfamily:sms:clpP:pgm_1:lysidine_TilS_N:AhpC:AhpF:chaperone_ClpB:Intracellular trafficking, secretion, and vesicular transport:Cellular processes and signaling:Carbohydrate Metabolism:Energy Metabolism:Lipid Metabolism:Global:Metabolism:DNA metabolism:DNA replication, recombination, and repair:Protein synthesis:tRNA and rRNA base modification:Protein fate:Protein folding and stabilization:Degradation of proteins, peptides, and glycopeptides:Cellular processes:Adaptations to atypical conditions:Unknown function:Enzymes of unknown specificity:Information storage and processing:Metabolism:Metabolism:Poorly characterized" 484 "Energy production and conversion:Dihydrodipicolinate synthase/N-acetylneuraminate lyase:Sulfite reductase, alpha subunit (flavoprotein):Aspartate/tyrosine/aromatic aminotransferase:Nucleoside-diphosphate-sugar epimerases:NADH:ubiquinone oxidoreductase subunit 11 or 4L (chain K):NAD-dependent aldehyde dehydrogenases:Non-ribosomal peptide synthetase modules and related proteins:Transcription-repair coupling factor (superfamily II helicase):Predicted transcriptional regulators:Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS/CutS homologs:Predicted RNA-binding protein containing a PIN domain:Amino acid transport and metabolism:Carbohydrate transport and metabolism:Transcription:Replication, recombination and repair:Cell wall/membrane/envelope biogenesis:Inorganic ion transport and metabolism:Glycolysis / Gluconeogenesis:Pentose and glucuronate interconversions:Ascorbate and aldarate metabolism:Fatty acid metabolism:Oxidative phosphorylation:Valine leucine and isoleucine degradation:Lysine biosynthesis:Lysine degradation:Arginine and proline metabolism:Histidine metabolism:Tryptophan metabolism:beta-Alanine metabolism:Glycerolipid metabolism:Pyruvate metabolism:Chloroalkane and chloroalkene degradation:Aminobenzoate degradation:Propanoate metabolism:Limonene and pinene degradation:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:Nucleotide excision repair:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:mfd:dapA:AA-adenyl-dom:Energy Metabolism:Replication and Repair:Carbohydrate Metabolism:Global:Metabolism:DNA metabolism:DNA replication, recombination, and repair:Amino acid biosynthesis:Aspartate family:Information storage and processing:Cellular processes and signaling:Metabolism:Poorly characterized:Genetic Information Processing:Xenobiotics Biodegradation and Metabolism:Metabolism of Terpenoids and Polyketides:Metabolism of Other Amino Acids:Metabolism:Amino Acid Metabolism:Lipid Metabolism" 485 "Putative regulatory, ligand-binding protein related to C-terminal domains of K+ channels:Transcriptional regulator:Predicted transcriptional regulators:Predicted transcriptional regulators:Predicted transcriptional regulators:Predicted membrane protein:Beta-lactamase class A:Transcription:Inorganic ion transport and metabolism:Arginine and proline metabolism:Metabolic pathways:Function unknown:sigma70-ECF:Defense mechanisms:Global:Cellular processes and signaling:Amino Acid Metabolism:Metabolism:Poorly characterized:Metabolism:Information storage and processing:Metabolism" 486 "Trk-type K+ transport systems, membrane components:Predicted transcriptional regulators:ABC-type proline/glycine betaine transport systems, periplasmic components:Predicted membrane protein:Amino acid transport and metabolism:Transcription:Inorganic ion transport and metabolism:ABC transporters:Function unknown:2a38:Poorly characterized:Membrane Transport:Transport and binding proteins:Cations and iron carrying compounds:Information storage and processing:Metabolism:Environmental Information Processing" 487 "Pyrroline-5-carboxylate reductase:Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily):ABC-type polar amino acid transport system, ATPase component:ABC-type multidrug transport system, ATPase component:Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis/translation initiation factor 2B, gamma/epsilon subunits (eIF-2Bgamma/eIF-2Bepsilon):Lysophospholipase:Predicted membrane protein:Arabinose efflux permease:Site-specific recombinase XerD:Amino acid transport and metabolism:Carbohydrate transport and metabolism:Lipid transport and metabolism:Translation, ribosomal structure and biogenesis:Replication, recombination and repair:Cell wall/membrane/envelope biogenesis:Arginine and proline metabolism:Starch and sucrose metabolism:Amino sugar and nucleotide sugar metabolism:Metabolic pathways:Biosynthesis of secondary metabolites:ABC transporters:General function prediction only:Function unknown:proC:Defense mechanisms:Poorly characterized:Carbohydrate Metabolism:Amino Acid Metabolism:Environmental Information Processing:Membrane Transport:Global:Metabolism:Amino acid biosynthesis:Glutamate family:Information storage and processing:Cellular processes and signaling:Metabolism:Metabolism" 488 "Energy production and conversion:Predicted sugar kinase:Ribosomal protein L11:Aspartate/tyrosine/aromatic aminotransferase:SAM-dependent methyltransferases:Transcriptional regulator:3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratases:Sec-independent protein secretion pathway component TatC:Predicted thioesterase:NAD-dependent aldehyde dehydrogenases:ADP-ribose pyrophosphatase:Gamma-aminobutyrate permease and related permeases:Transcriptional regulators:Leucyl aminopeptidase (aminopeptidase T):Uncharacterized domain/protein associated with RNAses G and E:Ornithine/acetylornithine aminotransferase:Pantothenate kinase, acetyl-CoA regulated:Amino acid transport and metabolism:Nucleotide transport and metabolism:Carbohydrate transport and metabolism:Coenzyme transport and metabolism:Lipid transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:Fatty acid biosynthesis:Alanine aspartate and glutamate metabolism:Arginine and proline metabolism:Nicotinate and nicotinamide metabolism:Pantothenate and CoA biosynthesis:Metabolic pathways:Biosynthesis of secondary metabolites:Ribosome:Protein export:Bacterial secretion system:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:panK_eukar:tatC:D1pyr5carbox2:L11_bact:Orn_aminotrans:Intracellular trafficking, secretion, and vesicular transport:Ribosomal proteins: synthesis and modification:Protein synthesis:Amino acids and amines:Energy metabolism:Metabolism:Global:Metabolism:Membrane Transport:Environmental Information Processing:Folding Sorting and Degradation:Translation:Genetic Information Processing:Metabolism of Cofactors and Vitamins:Amino Acid Metabolism:Information storage and processing:Lipid Metabolism:Cellular processes and signaling:Metabolism:Poorly characterized:Pantothenate and coenzyme A:Biosynthesis of cofactors, prosthetic groups, and carriers:Protein and peptide secretion and trafficking:Protein fate" 489 "Ribonuclease HI:cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases:Cell wall-associated hydrolases (invasion-associated proteins):Methyl-accepting chemotaxis protein:Flagellar motor component:Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase:Acetyltransferases, including N-acetylases of ribosomal proteins:Predicted transcriptional regulators:Signal transduction histidine kinase regulating citrate/malate metabolism:Predicted transcriptional regulator containing CBS domains:Uncharacterized protein conserved in bacteria:Uncharacterized protein conserved in bacteria:Lipid transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:Replication, recombination and repair:Cell wall/membrane/envelope biogenesis:Cell motility:Two-component system:Bacterial chemotaxis:Flagellar assembly:DNA replication:Protein export:General function prediction only:Function unknown:Signal transduction mechanisms:TIGR00147:sigpep_I_arch:Environmental Information Processing:Replication and Repair:Metabolism:Folding Sorting and Degradation:Poorly characterized:Cellular processes and signaling:Information storage and processing:Enzymes of unknown specificity:Unknown function:Genetic Information Processing:Cell Motility:Cellular Processes:Signal Transduction" 490 "Energy production and conversion:NADH:ubiquinone oxidoreductase 20 kD subunit and related Fe-S oxidoreductases:Uridylate kinase:NADH:ubiquinone oxidoreductase subunit 3 (chain A):NADH:ubiquinone oxidoreductase subunit 6 (chain J):NADH:ubiquinone oxidoreductase subunit 1 (chain H):NADH:ubiquinone oxidoreductase subunit 2 (chain N):NADH:ubiquinone oxidoreductase subunit 4 (chain M):NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit:Non-ribosomal peptide synthetase modules and related proteins:ABC-type polar amino acid transport system, ATPase component:ABC-type multidrug transport system, ATPase component:D-alanine-D-alanine ligase and related ATP-grasp enzymes:Acetyltransferases, including N-acetylases of ribosomal proteins:Amino acid transport and metabolism:Nucleotide transport and metabolism:Translation, ribosomal structure and biogenesis:Cell wall/membrane/envelope biogenesis:Inorganic ion transport and metabolism:Oxidative phosphorylation:Pyrimidine metabolism:D-Alanine metabolism:Peptidoglycan biosynthesis:Metabolic pathways:ABC transporters:Secondary metabolites biosynthesis, transport and catabolism:D_ala_D_alaTIGR:AA-adenyl-dom:NDH_I_N:nuoB_fam:NDH_I_M:NDH_I_L:pyrH_bact:Defense mechanisms:Metabolism:Metabolism:Cellular processes and signaling:Information storage and processing:Biosynthesis and degradation of murein sacculus and peptidoglycan:Cell envelope:Nucleotide and nucleoside interconversions:Purines, pyrimidines, nucleosides, and nucleotides:Electron transport:Energy metabolism:Metabolism:Global:Membrane Transport:Environmental Information Processing:Glycan Biosynthesis and Metabolism:Metabolism of Other Amino Acids:Nucleotide Metabolism:Energy Metabolism" 491 "Predicted ATPase of the PP-loop superfamily implicated in cell cycle control:Adenosylmethionine-8-amino-7-oxononanoate aminotransferase:Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II:Thiamine monophosphate synthase:Fructose-2,6-bisphosphatase:SAM-dependent methyltransferases:Mg2+ and Co2+ transporters:Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases:Signal peptidase I:Protease subunit of ATP-dependent Clp proteases:ADP-ribose pyrophosphatase:ABC-type multidrug transport system, ATPase component:Predicted phosphohydrolases:Fe2+ transport system protein A:Uncharacterized protein, possibly involved in aromatic compounds catabolism:Hydroxyethylthiazole kinase, sugar kinase family:Anti-sigma regulatory factor (Ser/Thr protein kinase):Na+/melibiose symporter and related transporters:Septum formation initiator:Uncharacterized domain/protein associated with RNAses G and E:Predicted ABC-type exoprotein transport system, permease component:Predicted oxidoreductase:Cell cycle control, cell division, chromosome partitioning:Amino acid transport and metabolism:Nucleotide transport and metabolism:Carbohydrate transport and metabolism:Coenzyme transport and metabolism:Lipid transport and metabolism:Translation, ribosomal structure and biogenesis:Posttranslational modification, protein turnover, chaperones:Inorganic ion transport and metabolism:Glycolysis / Gluconeogenesis:Arginine and proline metabolism:Bisphenol degradation:Polycyclic aromatic hydrocarbon degradation:Aminobenzoate degradation:Methane metabolism:Thiamine metabolism:Limonene and pinene degradation:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:Protein export:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:Signal transduction mechanisms:unchar_dom_1:corA:clpP:thiE:thiM:DapE-ArgE:spIIAB:sigpep_I_bact:lysidine_TilS_N:Intracellular trafficking, secretion, and vesicular transport:Defense mechanisms:Global:Folding Sorting and Degradation:Genetic Information Processing:Xenobiotics Biodegradation and Metabolism:Metabolism of Terpenoids and Polyketides:Metabolism of Cofactors and Vitamins:Amino Acid Metabolism:Energy Metabolism:Sporulation and germination:Carbohydrate Metabolism:Biosynthesis of cofactors, prosthetic groups, and carriers:Thiamine:Information storage and processing:Cellular processes and signaling:Metabolism:Poorly characterized:Cellular processes:Cations and iron carrying compounds:Transport and binding proteins:Degradation of proteins, peptides, and glycopeptides:Protein and peptide secretion and trafficking:Protein fate:tRNA and rRNA base modification:Protein synthesis:Metabolism:Metabolism" 492 "Methyl-accepting chemotaxis protein:Predicted nucleoside-diphosphate sugar epimerases:Flagellar biosynthesis/type III secretory pathway ATPase:UDP-glucose pyrophosphorylase:Flagellar hook-associated protein:Flagellin and related hook-associated proteins:Flagellar capping protein:Flagellar motor switch protein:Flagellar basal body rod protein:Flagellar hook-basal body protein:Flagellar hook protein FlgE:Flagellar biosynthesis/type III secretory pathway lipoprotein:Flagellar basal body protein:Sugar phosphate permease:Beta- N-acetylglucosaminidase:Carbohydrate transport and metabolism:Cell wall/membrane/envelope biogenesis:Cell motility:Pentose and glucuronate interconversions:Galactose metabolism:Starch and sucrose metabolism:Amino sugar and nucleotide sugar metabolism:Metabolic pathways:Biosynthesis of secondary metabolites:Two-component system:Bacterial chemotaxis:Flagellar assembly:Signal transduction mechanisms:fliG:fliI_yscN:galU:FlgC:FlgB:flgK_ends:flagell_flgL:FlgEFG_subfam:Intracellular trafficking, secretion, and vesicular transport:Metabolism:Carbohydrate Metabolism:Environmental Information Processing:Signal Transduction:Cellular Processes:Cell Motility:Global:Metabolism:Energy metabolism:ATP-proton motive force interconversion:Cellular processes:Chemotaxis and motility:Cell envelope:Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides:Cellular processes and signaling:Metabolism" 493 "tRNA-dihydrouridine synthase:Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase:Anthranilate/para-aminobenzoate synthases component I:Type I restriction-modification system methyltransferase subunit:Dihydropteroate synthase and related enzymes:Ribosomal protein L9:Anthranilate/para-aminobenzoate synthases component II:Restriction endonuclease S subunits:7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase:Predicted transcriptional regulators:Dihydroneopterin aldolase:Ribosomal protein L11 methylase:Predicted signaling protein consisting of a modified GGDEF domain and a DHH domain:Amino acid transport and metabolism:Coenzyme transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:Folate biosynthesis:Metabolic pathways:Ribosome:Signal transduction mechanisms:L9:prmA:hsdM:folB:pabB:trpG_papA:nifR3_yhdG:DHPS:folK:Defense mechanisms:Biosynthesis of cofactors, prosthetic groups, and carriers:Metabolism of Cofactors and Vitamins:Genetic Information Processing:Translation:Global:Metabolism:DNA metabolism:Restriction/modification:Protein synthesis:Ribosomal proteins: synthesis and modification:Unknown function:General:Metabolism:Folic acid:Information storage and processing:Cellular processes and signaling:Metabolism" 494 "Acetyl-CoA acetyltransferase:Phosphatidylserine/phosphatidylglycerophosphate/cardiolipin synthases and related enzymes:DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog:Predicted amino acid aldolase or racemase:Amino acid transport and metabolism:Lipid transport and metabolism:Transcription:Fatty acid biosynthesis:Fatty acid metabolism:Synthesis and degradation of ketone bodies:Valine leucine and isoleucine degradation:Lysine degradation:Benzoate degradation:Tryptophan metabolism:Glycerophospholipid metabolism:Pyruvate metabolism:Glyoxylate and dicarboxylate metabolism:Propanoate metabolism:Butanoate metabolism:Carbon fixation pathways in prokaryotes:Terpenoid backbone biosynthesis:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:Two-component system:RNA polymerase:AcCoA-C-Actrans:spore_V_AC:sigma70-ECF:Metabolism:Fatty acid and phospholipid metabolism:Other:Cellular processes:Sporulation and germination:Information storage and processing:Metabolism:Genetic Information Processing:Xenobiotics Biodegradation and Metabolism:Metabolism of Terpenoids and Polyketides:Amino Acid Metabolism:Lipid Metabolism:Energy Metabolism:Carbohydrate Metabolism:Environmental Information Processing:Signal Transduction:Global:Metabolism:Transcription" 495 "Adenosylmethionine-8-amino-7-oxononanoate aminotransferase:Acetyl-CoA acetyltransferase:Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases:ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components:Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain:Predicted transcriptional regulators:ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component:Uncharacterized conserved protein:Beta-lactamase class C and other penicillin binding proteins:Inosine-uridine nucleoside N-ribohydrolase:Arabinose efflux permease:Predicted integral membrane protein:Amino acid transport and metabolism:Nucleotide transport and metabolism:Carbohydrate transport and metabolism:Coenzyme transport and metabolism:Lipid transport and metabolism:Transcription:Inorganic ion transport and metabolism:Fatty acid metabolism:Synthesis and degradation of ketone bodies:Purine metabolism:Valine leucine and isoleucine degradation:Lysine degradation:Arginine and proline metabolism:Benzoate degradation:Tryptophan metabolism:Pyruvate metabolism:Glyoxylate and dicarboxylate metabolism:Propanoate metabolism:Butanoate metabolism:Carbon fixation pathways in prokaryotes:Nicotinate and nicotinamide metabolism:Terpenoid backbone biosynthesis:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:ABC transporters:Two-component system:General function prediction only:Function unknown:Signal transduction mechanisms:DapE-ArgE:AcCoA-C-Actrans:Defense mechanisms:Cellular processes and signaling:Carbohydrate Metabolism:Energy Metabolism:Lipid Metabolism:Nucleotide Metabolism:Amino Acid Metabolism:Metabolism of Cofactors and Vitamins:Metabolism of Terpenoids and Polyketides:Xenobiotics Biodegradation and Metabolism:Environmental Information Processing:Membrane Transport:Signal Transduction:Global:Metabolism:Fatty acid and phospholipid metabolism:Other:Protein fate:Degradation of proteins, peptides, and glycopeptides:Information storage and processing:Metabolism:Metabolism:Poorly characterized" 496 "Energy production and conversion:Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases:Transcriptional regulators of sugar metabolism:Acetyltransferases, including N-acetylases of ribosomal proteins:Glycosyl transferases, related to UDP-glucuronosyltransferase:Uncharacterized protein conserved in bacteria:Uncharacterized conserved protein:Leucine-rich repeat (LRR) protein:Signal transduction histidine kinase:Nucleotide transport and metabolism:Carbohydrate transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:Two-component system:General function prediction only:Function unknown:Signal transduction mechanisms:sensory_box:LPXTG_anchor:MGT:staph_tand_hypo:Poorly characterized:Signal Transduction:Regulatory functions:Small molecule interactions:Cellular processes:Toxin production and resistance:Cell envelope:Other:Information storage and processing:Cellular processes and signaling:Metabolism:Environmental Information Processing" 497 "FOG: GGDEF domain:Competence protein:Signal transduction histidine kinase:Two-component system:General function prediction only:Signal transduction mechanisms:sensory_box:GGDEF:Other:Signal Transduction:Regulatory functions:Small molecule interactions:Signal transduction:Environmental Information Processing:Cellular processes and signaling:Poorly characterized" 498 "Predicted hydrolase of the metallo-beta-lactamase superfamily:5'-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases:Predicted transcriptional regulators:Membrane transporters of cations and cationic drugs:AraC-type DNA-binding domain-containing proteins:Uncharacterized conserved protein:Beta-glucosidase/6-phospho-beta-glucosidase/beta-galactosidase:Uncharacterized protein conserved in bacteria:Uncharacterized conserved protein:Uncharacterized phage-encoded protein:Uncharacterized protein conserved in bacteria:Uncharacterized protein conserved in bacteria:Nucleotide transport and metabolism:Carbohydrate transport and metabolism:Transcription:Inorganic ion transport and metabolism:Purine metabolism:Pyrimidine metabolism:Cyanoamino acid metabolism:Starch and sucrose metabolism:Nicotinate and nicotinamide metabolism:Metabolic pathways:Biosynthesis of secondary metabolites:ABC transporters:General function prediction only:Function unknown:MG423:yxeA_fam:phage_pRha:Information storage and processing:Conserved:Hypothetical proteins:Prophage functions:Mobile and extrachromosomal element functions:Metabolism:Metabolism:Global:Membrane Transport:Environmental Information Processing:Metabolism of Cofactors and Vitamins:Metabolism of Other Amino Acids:Nucleotide Metabolism:Poorly characterized:Carbohydrate Metabolism:Metabolism" 499 "ATPases involved in chromosome partitioning:Topoisomerase IA:Coproporphyrinogen III oxidase and related Fe-S oxidoreductases:UDP-N-acetylglucosamine enolpyruvyl transferase:Cell division protein FtsI/penicillin-binding protein 2:Actin-like ATPase involved in cell morphogenesis:Uncharacterized conserved protein:Uncharacterized conserved protein:Putative enzyme of poly-gamma-glutamate biosynthesis (capsule formation):Uncharacterized protein conserved in bacteria:Predicted acetyltransferase:Uncharacterized conserved protein:Capsular polysaccharide biosynthesis protein:Capsular polysaccharide biosynthesis protein:Putative glucose uptake permease:Cell cycle control, cell division, chromosome partitioning:Carbohydrate transport and metabolism:Coenzyme transport and metabolism:Replication, recombination and repair:Cell wall/membrane/envelope biogenesis:Amino sugar and nucleotide sugar metabolism:Peptidoglycan biosynthesis:Porphyrin and chlorophyll metabolism:Metabolic pathways:Biosynthesis of secondary metabolites:General function prediction only:Function unknown:mreB:eps_fam:topB:murA:S_layer_CsaB:rSAM_HemZ:Biosynthesis and degradation of murein sacculus and peptidoglycan:Cell envelope:Heme, porphyrin, and cobalamin:Biosynthesis of cofactors, prosthetic groups, and carriers:Carbohydrates, organic alcohols, and acids:Transport and binding proteins:Protein and peptide secretion and trafficking:Protein fate:DNA replication, recombination, and repair:DNA metabolism:Metabolism:Metabolism:Global:Metabolism of Cofactors and Vitamins:Glycan Biosynthesis and Metabolism:Metabolism:Carbohydrate Metabolism:Poorly characterized:Cellular processes and signaling:Information storage and processing" 500 "ABC-type antimicrobial peptide transport system, permease component:Uncharacterized membrane-associated protein:Membrane-fusion protein:ABC-type antimicrobial peptide transport system, ATPase component:Predicted membrane protein:Uncharacterized protein conserved in bacteria:Cell wall/membrane/envelope biogenesis:ABC transporters:Function unknown:yxeA_fam:RND_mfp:Defense mechanisms:Poorly characterized:Membrane Transport:Transport and binding proteins:Unknown substrate:Hypothetical proteins:Conserved:Cellular processes and signaling:Environmental Information Processing" 501 "Energy production and conversion:Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain:Ribosomal protein L33:Protoheme ferro-lyase (ferrochelatase):FAD/FMN-containing dehydrogenases:Catalase:Parvulin-like peptidyl-prolyl isomerase:DNA-binding ferritin-like protein (oxidative damage protectant):Acyl carrier protein phosphodiesterase:Putative effector of murein hydrolase:Putative effector of murein hydrolase LrgA:Arsenate reductase and related proteins, glutaredoxin family:Small primase-like proteins (Toprim domain):Predicted transcriptional regulators:Pirin-related protein:Transcriptional regulators:Predicted transcriptional regulator:Uncharacterized protein conserved in bacteria:Arabinose efflux permease:Predicted membrane protein:ABC-type uncharacterized transport system, ATPase component:Uncharacterized protein conserved in bacteria:Carbohydrate transport and metabolism:Coenzyme transport and metabolism:Lipid transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:Replication, recombination and repair:Cell wall/membrane/envelope biogenesis:Posttranslational modification, protein turnover, chaperones:Inorganic ion transport and metabolism:Purine metabolism:Tryptophan metabolism:Glyoxylate and dicarboxylate metabolism:Methane metabolism:Porphyrin and chlorophyll metabolism:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:Ribosome:General function prediction only:Function unknown:hemH:glcD:efflux_EmrB:rpmG_bact:arsC_related:DNA interactions:Regulatory functions:Other:Energy metabolism:Metabolism:Metabolism:Global:Translation:Genetic Information Processing:Metabolism of Cofactors and Vitamins:Amino Acid Metabolism:Nucleotide Metabolism:Energy Metabolism:Poorly characterized:Carbohydrate Metabolism:Metabolism:Cellular processes and signaling:Information storage and processing:Heme, porphyrin, and cobalamin:Biosynthesis of cofactors, prosthetic groups, and carriers:Other:Transport and binding proteins:Ribosomal proteins: synthesis and modification:Protein synthesis" 502 "Energy production and conversion:Predicted membrane protein:ABC-type Na+ efflux pump, permease component:Peptidylarginine deiminase and related enzymes:Predicted membrane protein:Uncharacterized protein conserved in bacteria:Predicted membrane protein:Predicted choloylglycine hydrolase:Transcriptional regulator, effector-binding domain/component:Amino acid transport and metabolism:Transcription:Inorganic ion transport and metabolism:Arginine and proline metabolism:Metabolic pathways:ABC transporters:General function prediction only:Function unknown:Signal transduction mechanisms:T7_EssB:T7SS_EssA_Firm:T7_EssCb_Firm:T7_esaA_Nterm:Metabolism:Amino Acid Metabolism:Environmental Information Processing:Membrane Transport:Global:Metabolism:Protein fate:Protein and peptide secretion and trafficking:Information storage and processing:Cellular processes and signaling:Metabolism:Poorly characterized" 503 "Cysteine synthase:Predicted tRNA(5-methylaminomethyl-2-thiouridylate) methyltransferase, contains the PP-loop ATPase domain:Cystathionine beta-lyases/cystathionine gamma-synthases:ABC-type amino acid transport system, permease component:Nucleoside phosphorylase:ABC-type amino acid transport/signal transduction systems, periplasmic component/domain:ABC-type polar amino acid transport system, ATPase component:Uncharacterized conserved protein:Predicted Na+/dicarboxylate symporter:LuxS protein involved in autoinducer AI2 synthesis:Predicted transcriptional regulator:Methylase involved in ubiquinone/menaquinone biosynthesis:Uncharacterized protein conserved in bacteria:Amino acid transport and metabolism:Nucleotide transport and metabolism:Coenzyme transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:Cysteine and methionine metabolism:Selenocompound metabolism:Nitrogen metabolism:Sulfur metabolism:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:Sulfur relay system:General function prediction only:Function unknown:Signal transduction mechanisms:trmU:rrf2_super:cysKM:MTA/SAH-Nsdase:HEQRo_perm_3TM:Poorly characterized:Protein synthesis:Salvage of nucleosides and nucleotides:Purines, pyrimidines, nucleosides, and nucleotides:Metabolism:Metabolism:Global:Folding Sorting and Degradation:Genetic Information Processing:Metabolism of Other Amino Acids:Amino Acid Metabolism:tRNA and rRNA base modification:Energy Metabolism:Transport and binding proteins:Amino acids, peptides and amines:Unknown function:General:Amino acid biosynthesis:Serine family:Information storage and processing:Cellular processes and signaling:Metabolism" 504 "Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II:cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases:Sugar phosphate isomerases/epimerases:Predicted transcriptional regulators:Uncharacterized protein conserved in bacteria:Peptidylarginine deiminase and related enzymes:Predicted membrane protein:Zinc metalloprotease (elastase):ABC-type proline/glycine betaine transport system, permease component:Siderophore synthetase component:Amino acid transport and metabolism:Carbohydrate transport and metabolism:Lipid transport and metabolism:Transcription:Fatty acid metabolism:Alanine aspartate and glutamate metabolism:Arginine and proline metabolism:Nitrogen metabolism:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:ABC transporters:Secondary metabolites biosynthesis, transport and catabolism:Function unknown:Signal transduction mechanisms:Metabolism:Energy Metabolism:Lipid Metabolism:Amino Acid Metabolism:Environmental Information Processing:Membrane Transport:Global:Metabolism:Information storage and processing:Cellular processes and signaling:Metabolism:Poorly characterized" 505 "Predicted esterase:NTP pyrophosphohydrolases including oxidative damage repair enzymes:tmRNA-binding protein:Fe2+/Zn2+ uptake regulation proteins:Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain:Predicted transcriptional regulators:ABC-type Mn/Zn transport systems, ATPase component:Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily:Esterase/lipase:GAF domain-containing protein:Uncharacterized conserved protein:Predicted integral membrane protein:Transcription:Replication, recombination and repair:Cell wall/membrane/envelope biogenesis:Posttranslational modification, protein turnover, chaperones:Inorganic ion transport and metabolism:ABC transporters:General function prediction only:Function unknown:Signal transduction mechanisms:smpB:intg_mem_TP0381:Protein synthesis:Membrane Transport:Environmental Information Processing:Poorly characterized:Metabolism:Cellular processes and signaling:Information storage and processing:Other" 506 "Sulfite reductase, alpha subunit (flavoprotein):Predicted epimerase, PhzC/PhzF homolog:Glycosyltransferase:ABC-type cobalt transport system, permease component CbiQ and related transporters:Predicted permease:Uncharacterized membrane protein, putative virulence factor:ABC-type multidrug transport system, ATPase component:Cell wall/membrane/envelope biogenesis:Inorganic ion transport and metabolism:Fatty acid metabolism:Tryptophan metabolism:Aminobenzoate degradation:Microbial metabolism in diverse environments:ABC transporters:General function prediction only:PhzF_family:LPXTG_anchor:Defense mechanisms:Toxin production and resistance:Lipid Metabolism:Amino Acid Metabolism:Xenobiotics Biodegradation and Metabolism:Environmental Information Processing:Membrane Transport:Global:Metabolism:Cellular processes:Metabolism:Cell envelope:Other:Cellular processes and signaling:Metabolism:Poorly characterized" 507 "Energy production and conversion:Uncharacterized conserved protein:Thioredoxin reductase:Thiol-disulfide isomerase and thioredoxins:Predicted transcriptional regulators:NAD-dependent aldehyde dehydrogenases:Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases):Uncharacterized conserved protein:Transcriptional regulator:Predicted metal-sulfur cluster biosynthetic enzyme:Truncated hemoglobins:Predicted Zn-dependent protease:Predicted dithiol-disulfide isomerase involved in polyketide biosynthesis:Predicted esterase of the alpha-beta hydrolase superfamily:Uncharacterized protein conserved in bacteria:Lipid transport and metabolism:Transcription:Posttranslational modification, protein turnover, chaperones:Glycolysis / Gluconeogenesis:Pyrimidine metabolism:Metabolic pathways:Microbial metabolism in diverse environments:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:Function unknown:TIGR00106:TRX_reduct:Metabolism:Global:Nucleotide Metabolism:Poorly characterized:Carbohydrate Metabolism:Metabolism:Metabolism:Cellular processes and signaling:Information storage and processing:General:Unknown function:Electron transport:Energy metabolism" 508 "Energy production and conversion:Molybdopterin biosynthesis enzyme:FOG: Ankyrin repeat:Predicted oxidoreductases (related to aryl-alcohol dehydrogenases):DNA-directed RNA polymerase specialized sigma subunit:Uncharacterized conserved protein:Arabinose efflux permease:Competence protein:Carbohydrate transport and metabolism:Coenzyme transport and metabolism:Transcription:RNA polymerase:General function prediction only:Function unknown:molyb_syn:spore_sigmaE:Genetic Information Processing:Poorly characterized:Information storage and processing:Sporulation and germination:Cellular processes:Transcription:Metabolism" 509 "Kef-type K+ transport systems, membrane components:ATPase components of ABC transporters with duplicated ATPase domains:Transcriptional regulator:Predicted xylanase/chitin deacetylase:Putative threonine efflux protein:Predicted membrane protein:D-serine dehydratase:Predicted thioesterase involved in non-ribosomal peptide biosynthesis:Uncharacterized protein conserved in bacteria:Signal transduction histidine kinase:Amino acid transport and metabolism:Carbohydrate transport and metabolism:Transcription:Inorganic ion transport and metabolism:Glycine serine and threonine metabolism:Limonene and pinene degradation:Biosynthesis of unsaturated fatty acids:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:Function unknown:Signal transduction mechanisms:SASP_gamma:D_Ser_am_lyase:M6dom_TIGR03296:Sporulation and germination:Lipid Metabolism:Information storage and processing:Cellular processes and signaling:Metabolism:Poorly characterized:Metabolism:Cellular processes:Amino acids and amines:Energy metabolism:Metabolism of Terpenoids and Polyketides:Amino Acid Metabolism" 510 "Arginyl-tRNA synthetase:Thiamine biosynthesis ATP pyrophosphatase:Adenine/guanine phosphoribosyltransferases and related PRPP-binding proteins:Coproporphyrinogen III oxidase and related Fe-S oxidoreductases:UDP-N-acetylglucosamine enolpyruvyl transferase:Collagenase and related proteases:ABC-type spermidine/putrescine transport system, permease component I:ABC-type spermidine/putrescine transport system, permease component II:Uncharacterized conserved protein:Uncharacterized protein conserved in bacteria:ABC-type spermidine/putrescine transport systems, ATPase components:Predicted O-methyltransferase:Uncharacterized protein conserved in bacteria:Amino acid transport and metabolism:Nucleotide transport and metabolism:Coenzyme transport and metabolism:Translation, ribosomal structure and biogenesis:Cell wall/membrane/envelope biogenesis:Posttranslational modification, protein turnover, chaperones:Purine metabolism:Phenylalanine metabolism:Amino sugar and nucleotide sugar metabolism:Peptidoglycan biosynthesis:Thiamine metabolism:Porphyrin and chlorophyll metabolism:Aminoacyl-tRNA biosynthesis:Metabolic pathways:Biosynthesis of secondary metabolites:ABC transporters:Sulfur relay system:General function prediction only:Function unknown:TIGR00342:argS:murA:apt:S_layer_CsaB:rSAM_HemZ:Heme, porphyrin, and cobalamin:Cell envelope:Biosynthesis and degradation of murein sacculus and peptidoglycan:Information storage and processing:Cellular processes and signaling:Metabolism:Poorly characterized:Metabolism:Global:Membrane Transport:Environmental Information Processing:Metabolism:Folding Sorting and Degradation:Translation:Genetic Information Processing:Metabolism of Cofactors and Vitamins:Glycan Biosynthesis and Metabolism:Amino Acid Metabolism:Nucleotide Metabolism:Purines, pyrimidines, nucleosides, and nucleotides:Carbohydrate Metabolism:Salvage of nucleosides and nucleotides:Protein synthesis:tRNA aminoacylation:tRNA and rRNA base modification:Protein fate:Protein and peptide secretion and trafficking:Biosynthesis of cofactors, prosthetic groups, and carriers" 511 "Energy production and conversion:Uncharacterized conserved protein:Lactoylglutathione lyase and related lyases:Translation elongation factors (GTPases):ATPases involved in chromosome partitioning:Mg2+ and Co2+ transporters:ABC-type multidrug transport system, permease component:NAD-dependent aldehyde dehydrogenases:Lactate dehydrogenase and related dehydrogenases:ABC-type multidrug transport system, ATPase and permease components:Oligoendopeptidase F:Uncharacterized membrane protein:Transcriptional regulators:Fe2+ transport system protein A:Uncharacterized conserved protein:Formyltetrahydrofolate synthetase:Uncharacterized protein conserved in bacteria:Site-specific recombinase XerD:Cell cycle control, cell division, chromosome partitioning:Amino acid transport and metabolism:Nucleotide transport and metabolism:Coenzyme transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:Replication, recombination and repair:Inorganic ion transport and metabolism:Alanine aspartate and glutamate metabolism:Tyrosine metabolism:Bisphenol degradation:Pyruvate metabolism:Polycyclic aromatic hydrocarbon degradation:Aminobenzoate degradation:Butanoate metabolism:One carbon pool by folate:Carbon fixation pathways in prokaryotes:Limonene and pinene degradation:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:General function prediction only:Function unknown:TIGR00106:pepF:small_GTP:corA:eps_fam:spo_II_M:Defense mechanisms:Metabolism of Terpenoids and Polyketides:Metabolism of Cofactors and Vitamins:Amino Acid Metabolism:Energy Metabolism:Carbohydrates, organic alcohols, and acids:Carbohydrate Metabolism:Cations and iron carrying compounds:Cellular processes:Sporulation and germination:Unknown function:General:Information storage and processing:Cellular processes and signaling:Metabolism:Poorly characterized:Transport and binding proteins:Degradation of proteins, peptides, and glycopeptides:Protein fate:Metabolism:Global:Metabolism:Xenobiotics Biodegradation and Metabolism" 512 "Riboflavin synthase beta-chain:Ornithine carbamoyltransferase:3,4-dihydroxy-2-butanone 4-phosphate synthase:Argininosuccinate synthase:Argininosuccinate lyase:Riboflavin synthase alpha chain:Nucleoside-diphosphate-sugar epimerases:Acetylglutamate kinase:ABC-type amino acid transport system, permease component:ABC-type amino acid transport/signal transduction systems, periplasmic component/domain:ABC-type polar amino acid transport system, ATPase component:N-acetylglutamate synthase and related acetyltransferases:N-acetylglutamate synthase (N-acetylornithine aminotransferase):Pyrimidine reductase, riboflavin biosynthesis:K+-transporting ATPase, A chain:K+-transporting ATPase, c chain:High-affinity K+ transport system, ATPase chain B:Uncharacterized protein conserved in bacteria:Ornithine/acetylornithine aminotransferase:Amino acid transport and metabolism:Carbohydrate transport and metabolism:Coenzyme transport and metabolism:Cell wall/membrane/envelope biogenesis:Inorganic ion transport and metabolism:Alanine aspartate and glutamate metabolism:Lysine biosynthesis:Arginine and proline metabolism:Riboflavin metabolism:Metabolic pathways:Biosynthesis of secondary metabolites:Two-component system:Function unknown:Signal transduction mechanisms:argG:lumazine-synth:ArgJ:ribE:ribD_Cterm:ribA:orni_carb_tr:kdpA:kdpC:argD:argB:argH:ATPase_P-type:HEQRo_perm_3TM:M6dom_TIGR03296:Biosynthesis of cofactors, prosthetic groups, and carriers:Glutamate family:Amino acid biosynthesis:Cations and iron carrying compounds:Amino acids, peptides and amines:Transport and binding proteins:Metabolism:Metabolism:Global:Signal Transduction:Environmental Information Processing:Metabolism of Cofactors and Vitamins:Poorly characterized:Amino Acid Metabolism:Metabolism:Cellular processes and signaling:Riboflavin, FMN, and FAD" 513 "Guanylate kinase:6-phosphofructokinase:Phosphoribosylpyrophosphate synthetase:Uridylate kinase:Cell division protein FtsI/penicillin-binding protein 2:Non-ribosomal peptide synthetase modules and related proteins:N-acetylglucosamine-1-phosphate uridyltransferase (contains nucleotidyltransferase and I-patch acetyltransferase domains):Predicted Fe-S oxidoreductase:Uncharacterized protein conserved in bacteria:Uncharacterized protein conserved in bacteria:Amino acid transport and metabolism:Nucleotide transport and metabolism:Carbohydrate transport and metabolism:Cell wall/membrane/envelope biogenesis:Glycolysis / Gluconeogenesis:Pentose phosphate pathway:Fructose and mannose metabolism:Galactose metabolism:Purine metabolism:Pyrimidine metabolism:D-Alanine metabolism:Amino sugar and nucleotide sugar metabolism:Methane metabolism:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:Function unknown:glmU:TIGR01212:ribP_PPkin:AA-adenyl-dom:pyrH_bact:PFKA_ATP:guanyl_kin:thiopep_precurs:Unknown function:Carbohydrate Metabolism:Energy Metabolism:Nucleotide Metabolism:Metabolism of Other Amino Acids:Global:Metabolism:Central intermediary metabolism:Amino sugars:Energy metabolism:Glycolysis/gluconeogenesis:Purines, pyrimidines, nucleosides, and nucleotides:Nucleotide and nucleoside interconversions:Purine ribonucleotide biosynthesis:Cellular processes:Toxin production and resistance:Metabolism:Enzymes of unknown specificity:Cellular processes and signaling:Metabolism:Poorly characterized" 514 "Uroporphyrinogen-III methylase:Sulfite reductase, beta subunit (hemoprotein):3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase and related enzymes:ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component:Adenylylsulfate kinase and related kinases:ABC-type nitrate/sulfonate/bicarbonate transport system, permease component:ABC-type dipeptide/oligopeptide/nickel transport systems, permease components:ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components:Predicted permeases:ABC-type dipeptide transport system, periplasmic component:ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component:ABC-type dipeptide/oligopeptide/nickel transport systems, permease components:ATP sulfurylase (sulfate adenylyltransferase):ABC-type sulfate transport system, permease component:Amino acid transport and metabolism:Coenzyme transport and metabolism:Inorganic ion transport and metabolism:Purine metabolism:Selenocompound metabolism:Porphyrin and chlorophyll metabolism:Nitrogen metabolism:Sulfur metabolism:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:ABC transporters:General function prediction only:sopT:cysH:apsK:3a0106s02:3a0106s03:cobA_cysG_Cterm:oligo_HPY:SsuA_fam:Heme, porphyrin, and cobalamin:Energy Metabolism:Nucleotide Metabolism:Metabolism of Other Amino Acids:Metabolism of Cofactors and Vitamins:Environmental Information Processing:Membrane Transport:Global:Metabolism:Central intermediary metabolism:Sulfur metabolism:Transport and binding proteins:Amino acids, peptides and amines:Anions:Other:Biosynthesis of cofactors, prosthetic groups, and carriers:Metabolism:Metabolism:Poorly characterized" 515 "DNA polymerase I - 3'-5' exonuclease and polymerase domains:DNA or RNA helicases of superfamily II:Transcription:Replication, recombination and repair:Purine metabolism:Pyrimidine metabolism:Metabolic pathways:DNA replication:Base excision repair:Nucleotide excision repair:Homologous recombination:Metabolism:Global:Information storage and processing:Metabolism:Replication and Repair:Genetic Information Processing:Nucleotide Metabolism" 516 "Chromatin structure and dynamics:Energy production and conversion:Deacetylases, including yeast histone deacetylase and acetoin utilization protein:Predicted translation initiation factor 2B subunit, eIF-2B alpha/beta/delta family:Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases:Sugar kinases, ribokinase family:Glycerol uptake facilitator and related permeases (Major Intrinsic Protein Family):Phosphotransferase system, fructose-specific IIC component:Phosphotransferase system cellobiose-specific component IIB:Phosphotransferase system cellobiose-specific component IIC:Alpha-galactosidases/6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases:Transcriptional regulators:L-lactate permease:Saccharopine dehydrogenase and related proteins:Selenocysteine synthase [seryl-tRNASer selenium transferase]:H+/gluconate symporter and related permeases:Signal transduction histidine kinase regulating citrate/malate metabolism:Predicted transcriptional regulator with C-terminal CBS domains:Predicted amidohydrolase:Predicted acetyltransferase:Predicted kinase:Amino acid transport and metabolism:Carbohydrate transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:Glycolysis / Gluconeogenesis:Pentose phosphate pathway:Pentose and glucuronate interconversions:Fructose and mannose metabolism:Pyrimidine metabolism:Cysteine and methionine metabolism:Selenocompound metabolism:Aminoacyl-tRNA biosynthesis:Metabolic pathways:Microbial metabolism in diverse environments:Phosphotransferase system (PTS):Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:Signal transduction mechanisms:cello_pts_IIC:salvage_mtnA:gntP:lctP:FRU:MIP:selA_rel:MTRK:EF_0839:EF_0837:Poorly characterized:Carbohydrate Metabolism:Nucleotide Metabolism:Amino Acid Metabolism:Metabolism of Other Amino Acids:Genetic Information Processing:Translation:Environmental Information Processing:Membrane Transport:Global:Metabolism:Transport and binding proteins:Unknown substrate:Carbohydrates, organic alcohols, and acids:Hypothetical proteins:Conserved:Unknown function:Enzymes of unknown specificity:Amino acid biosynthesis:Aspartate family:Signal transduction:PTS:Information storage and processing:Cellular processes and signaling:Metabolism:Metabolism" 517 "Zn-dependent hydrolases, including glyoxylases:Na+-driven multidrug efflux pump:Predicted permease:Chemotaxis protein histidine kinase and related kinases:Shikimate kinase:Predicted xylanase/chitin deacetylase:Methyl-accepting chemotaxis protein:ABC-type multidrug transport system, ATPase component:ABC-type dipeptide/oligopeptide/nickel transport systems, permease components:Uncharacterized protein conserved in bacteria:Transcriptional regulators:Regulators of stationary/sporulation gene expression:Predicted membrane protein:GTPases:Predicted extracellular nuclease:Predicted membrane protein:Uncharacterized protein conserved in bacteria:Uncharacterized conserved protein:Beta- N-acetylglucosaminidase:Amino acid transport and metabolism:Carbohydrate transport and metabolism:Transcription:Cell motility:Inorganic ion transport and metabolism:Phenylalanine tyrosine and tryptophan biosynthesis:Metabolic pathways:Biosynthesis of secondary metabolites:ABC transporters:Two-component system:Bacterial chemotaxis:Ribosome:General function prediction only:Function unknown:Signal transduction mechanisms:matE:rpmH_bact:lp_hng_hel_AbrB:spore_ybaN_pdaB:spore_ytfJ:spore_ysxE:GTP_HflX:Defense mechanisms:Metabolism:Global:Cell Motility:Cellular Processes:Signal Transduction:Metabolism:Membrane Transport:Environmental Information Processing:Translation:Genetic Information Processing:Ribosomal proteins: synthesis and modification:Amino Acid Metabolism:Transport and binding proteins:Other:Cellular processes:Sporulation and germination:Unknown function:General:Information storage and processing:Cellular processes and signaling:Metabolism:Poorly characterized:Protein synthesis:DNA interactions:Regulatory functions" 518 "tRNA-dihydrouridine synthase:Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase:Anthranilate/para-aminobenzoate synthases component I:Formamidopyrimidine-DNA glycosylase:Dihydropteroate synthase and related enzymes:Ribosomal protein L9:Aspartate/tyrosine/aromatic aminotransferase:Anthranilate/para-aminobenzoate synthases component II:Alanine racemase:7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase:Deoxyxylulose-5-phosphate synthase:RecG-like helicase:Disulfide bond chaperones of the HSP33 family:Predicted transcriptional regulators:Dihydroneopterin aldolase:Predicted esterase of the alpha-beta hydrolase superfamily:Outer membrane lipoprotein-sorting protein:Predicted secreted protein containing a PDZ domain:Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains:Predicted signaling protein consisting of a modified GGDEF domain and a DHH domain:Amino acid transport and metabolism:Coenzyme transport and metabolism:Lipid transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:Replication, recombination and repair:Cell wall/membrane/envelope biogenesis:Posttranslational modification, protein turnover, chaperones:D-Alanine metabolism:Folate biosynthesis:Terpenoid backbone biosynthesis:Metabolic pathways:Biosynthesis of secondary metabolites:Ribosome:Base excision repair:Homologous recombination:General function prediction only:Signal transduction mechanisms:L9:dxs:sensory_box:alr:folB:pabB:trpG_papA:fpg:recG:nifR3_yhdG:DHPS:folK:spore_yqfD:Sporulation and germination:Cellular processes:Ribosomal proteins: synthesis and modification:Protein synthesis:DNA replication, recombination, and repair:DNA metabolism:Small molecule interactions:Regulatory functions:Metabolism:Metabolism:Global:Replication and Repair:Translation:Genetic Information Processing:Metabolism of Terpenoids and Polyketides:Metabolism of Cofactors and Vitamins:Biosynthesis of cofactors, prosthetic groups, and carriers:Metabolism of Other Amino Acids:Folic acid:Thiamine:Cell envelope:Biosynthesis and degradation of murein sacculus and peptidoglycan:Information storage and processing:Cellular processes and signaling:Metabolism:Poorly characterized:General:Unknown function" 519 "Replicative DNA helicase:Replication, recombination and repair:DNA replication:DnaB:DnaD_dom:Prophage functions:Information storage and processing:DNA replication, recombination, and repair:Replication and Repair:DNA metabolism:Genetic Information Processing:Mobile and extrachromosomal element functions" 520 "Energy production and conversion:Glutamate synthase domain 2:ABC-type branched-chain amino acid transport systems, ATPase component:Branched-chain amino acid ABC-type transport system, permease components:Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily):Predicted GTPases:DNA-directed RNA polymerase specialized sigma subunit:Cytochrome bd-type quinol oxidase, subunit 1:Beta-lactamase class C and other penicillin binding proteins:Siderophore synthetase component:Predicted permease, DMT superfamily:Amino acid transport and metabolism:Transcription:Oxidative phosphorylation:Alanine aspartate and glutamate metabolism:Benzoate degradation:Nitrogen metabolism:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:ABC transporters:RNA polymerase:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:TIGR00157:spore_sigG:spore_II_GA:Defense mechanisms:Metabolism:Poorly characterized:Metabolism:Global:Membrane Transport:Environmental Information Processing:Metabolism:Transcription:Genetic Information Processing:Xenobiotics Biodegradation and Metabolism:Amino Acid Metabolism:Protein synthesis:Energy Metabolism:Translation factors:Cellular processes:Sporulation and germination:Information storage and processing:Cellular processes and signaling" 521 "Energy production and conversion:Ferredoxin:Homoserine trans-succinylase:Plastocyanin:Phage-related protein:Amino acid transport and metabolism:Cysteine and methionine metabolism:Sulfur metabolism:Metabolic pathways:Biosynthesis of secondary metabolites:Function unknown:metA:phi3626_gp14_N:phage_arpU:DNA interactions:Energy Metabolism:Amino Acid Metabolism:Global:Metabolism:Regulatory functions:Metabolism:Mobile and extrachromosomal element functions:Prophage functions:Amino acid biosynthesis:Aspartate family:Metabolism:Poorly characterized" 522 "Predicted branched-chain amino acid permease (azaleucine resistance):Predicted transcriptional regulators:Acetyltransferases, including N-acetylases of ribosomal proteins:Predicted transcriptional regulators:Predicted flavin-nucleotide-binding protein structurally related to pyridoxine 5'-phosphate oxidase:Amino acid transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:Histidine metabolism:Tyrosine metabolism:Benzoate degradation:Selenocompound metabolism:Polycyclic aromatic hydrocarbon degradation:Naphthalene degradation:Aminobenzoate degradation:Ethylbenzene degradation:Limonene and pinene degradation:Microbial metabolism in diverse environments:General function prediction only:PPOX_FMN_DR2398:Metabolism:Amino Acid Metabolism:Metabolism of Other Amino Acids:Metabolism of Terpenoids and Polyketides:Xenobiotics Biodegradation and Metabolism:Global:Metabolism:Information storage and processing:Metabolism:Poorly characterized" 523 "ABC-type sugar transport system, permease component:Predicted redox protein, regulator of disulfide bond formation:Zn-dependent hydrolases, including glyoxylases:Putative GTPases (G3E family):Rhodanese-related sulfurtransferase:ABC-type sugar transport systems, permease components:ABC-type Fe3+ transport system, permease component:Amidases related to nicotinamidase:ABC-type sugar transport system, periplasmic component:ABC-type Fe3+ transport system, periplasmic component:Glycerol-3-phosphate responsive antiterminator (mRNA-binding):Uncharacterized conserved protein:Cation transport ATPase:Copper chaperone:ABC-type sugar transport systems, ATPase components:ABC-type spermidine/putrescine transport systems, ATPase components:Amino acid transport and metabolism:Carbohydrate transport and metabolism:Transcription:Posttranslational modification, protein turnover, chaperones:Inorganic ion transport and metabolism:Biosynthesis of siderophore group nonribosomal peptides:Biosynthesis of secondary metabolites:ABC transporters:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:Function unknown:TIGR00003:phnS2:PhnU2:PhnT2:Information storage and processing:Cations and iron carrying compounds:Amino acids, peptides and amines:Transport and binding proteins:Metabolism:Global:Membrane Transport:Environmental Information Processing:Metabolism:Metabolism of Terpenoids and Polyketides:Poorly characterized:Metabolism:Cellular processes and signaling" 524 "Energy production and conversion:Phosphoribosylformylglycinamidine (FGAM) synthase, synthetase domain:Phosphoribosylformylglycinamidine (FGAM) synthase, glutamine amidotransferase domain:Phosphoribosylaminoimidazole (AIR) synthetase:Phosphoribosylaminoimidazolesuccinocarboxamide (SAICAR) synthase:Folate-dependent phosphoribosylglycinamide formyltransferase PurN:3-dehydroquinate synthetase:DNA repair exonuclease:Sugar kinases, ribokinase family:Rieske Fe-S protein:UDP-N-acetylglucosamine enolpyruvyl transferase:ABC-type sugar transport system, ATPase component:Dipeptidyl aminopeptidases/acylaminoacyl-peptidases:Transcriptional regulators:Phosphoribosylformylglycinamidine (FGAM) synthase, PurS component:ABC-type ribose transport system, auxiliary component:Teichoic acid biosynthesis proteins:Predicted N-acetylglucosamine kinase:Uncharacterized protein conserved in bacteria:Amino acid transport and metabolism:Nucleotide transport and metabolism:Carbohydrate transport and metabolism:Transcription:Replication, recombination and repair:Cell wall/membrane/envelope biogenesis:Pentose phosphate pathway:Oxidative phosphorylation:Purine metabolism:Glycine serine and threonine metabolism:Phenylalanine tyrosine and tryptophan biosynthesis:Amino sugar and nucleotide sugar metabolism:Peptidoglycan biosynthesis:One carbon pool by folate:Metabolic pathways:Biosynthesis of secondary metabolites:ABC transporters:Function unknown:purC:TIGR00302:PurN:wecG_tagA_cpsF:purM:murA:aroB:FGAM_synth_II:FGAM_synth_I:D_ribokin_bact:WXG100_ESAT6:Poorly characterized:Carbohydrate Metabolism:Energy Metabolism:Nucleotide Metabolism:Amino Acid Metabolism:Glycan Biosynthesis and Metabolism:Metabolism of Cofactors and Vitamins:Environmental Information Processing:Membrane Transport:Global:Metabolism:Energy metabolism:Sugars:Purines, pyrimidines, nucleosides, and nucleotides:Purine ribonucleotide biosynthesis:Amino acid biosynthesis:Aromatic amino acid family:Cell envelope:Biosynthesis and degradation of murein sacculus and peptidoglycan:Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides:Information storage and processing:Cellular processes and signaling:Metabolism:Metabolism" 525 "Predicted flavoprotein:SAM-dependent methyltransferases:Transcriptional regulator:Predicted hydrolase (HAD superfamily):Transcriptional regulator:Acetyltransferases, including N-acetylases of ribosomal proteins:Uncharacterized conserved protein:Acyl dehydratase:Allophanate hydrolase subunit 1:Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains:Uncharacterized protein conserved in bacteria:Amino acid transport and metabolism:Lipid transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:Function unknown:Signal transduction mechanisms:sensory_box:TIGR00370:TIGR00702:HAD-SF-IA-v3:thiopep_ocin:Cellular processes:Small molecule interactions:Regulatory functions:Unknown function:Poorly characterized:Cellular processes and signaling:Information storage and processing:Enzymes of unknown specificity:Metabolism:Conserved:Hypothetical proteins:Toxin production and resistance" 526 "Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases):Predicted phosphohydrolases:Beta-lactamase class C and other penicillin binding proteins:Predicted membrane protein:Predicted molecular chaperone distantly related to HSP70-fold metalloproteases:Lipid transport and metabolism:Posttranslational modification, protein turnover, chaperones:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:Function unknown:spore_ger_x_C:Defense mechanisms:Poorly characterized:Metabolism:Cellular processes and signaling:Sporulation and germination:Cellular processes" 527 "EMAP domain:Dihydrodipicolinate reductase:ATP-dependent Lon protease, bacterial type:Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family:Na+-driven multidrug efflux pump:Signal transduction histidine kinase:Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain:Predicted ATP-dependent serine protease:Phosphatidylserine/phosphatidylglycerophosphate/cardiolipin synthases and related enzymes:Acyl-CoA hydrolase:Predicted nucleic-acid-binding protein (contains the HHH domain):Predicted transcriptional regulators:Na+/melibiose symporter and related transporters:Predicted permeases:ABC-type uncharacterized transport system, permease component:Uncharacterized protein conserved in bacteria:Signal transduction histidine kinase:Amino acid transport and metabolism:Carbohydrate transport and metabolism:Lipid transport and metabolism:Transcription:Posttranslational modification, protein turnover, chaperones:Oxidative phosphorylation:Lysine biosynthesis:Streptomycin biosynthesis:Inositol phosphate metabolism:Glycerophospholipid metabolism:Limonene and pinene degradation:Biosynthesis of unsaturated fatty acids:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:Two-component system:General function prediction only:Function unknown:Signal transduction mechanisms:dapB:sensory_box:sms:rarD:efflux_EmrB:lon:matE:Defense mechanisms:Poorly characterized:Carbohydrate Metabolism:Energy Metabolism:Lipid Metabolism:Amino Acid Metabolism:Metabolism of Terpenoids and Polyketides:Biosynthesis of Other Secondary Metabolites:Environmental Information Processing:Signal Transduction:Global:Metabolism:Regulatory functions:Small molecule interactions:DNA metabolism:DNA replication, recombination, and repair:Protein fate:Degradation of proteins, peptides, and glycopeptides:Transport and binding proteins:Unknown substrate:Other:Amino acid biosynthesis:Aspartate family:Information storage and processing:Cellular processes and signaling:Metabolism:Metabolism"