MSMEG_5249 MSMEG_5249 Serine hydroxymethyltransferase (SHMT) (Serine methylase) (EC 2.1.2.1)
Mycobacterium smegmatis (strain ATCC 700084 / mc(2)155)

Mycobacterium smegmatis (strain ATCC 700084 / mc(2)155)

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Summary

	Locus Tag	Symbol	Synonyms	Product	Protein Synonyms	Start	End	Strand	PubMed ID
MSMEG_5249	MSMEG_5249	glyA	glyA, MSMEG_5249, MSMEI_5111		Serine hydroxymethyltransferase (SHMT) (Serine methylase) (EC 2.1.2.1)				17295914, 18955433, 20094657

Regulatory Modules

	Residual	Motif 1	Expression Plot
msm_bicluster_0077	0.61
msm_bicluster_0098	0.44

XReference

Uniprot	NCBI Gene	NCBI Protein	EnsemblBacteria	InterPro	EggNOG	OrthoDB
A0R2V7	4534074;	WP_011730415.1, YP_889495.1	ABK71001, AFP41555	IPR015424, IPR015421, IPR015422, IPR001085, IPR019798	ENOG4105C65, COG0112	EOG6Z0QB2

Mutations

Line	Position	Effect	Impact	Class	Percent Frequency	AA

Transposon mutants

Title	Insert	TAG Module
NA

Homology

Orthologues	Paralogues

Functions

Catalytic Activity	KEGG Ontology	Pathways
5,10-methylenetetrahydrofolate + glycine + H(2)O = tetrahydrofolate + L-serine, ECO:0000255|HAMAP-Rule:MF_00051}.	msb:LJ00_25960, msg:MSMEI_5111, msm:MSMEG_5249	One-carbon metabolism, tetrahydrofolate interconversion. {ECO:0000255|HAMAP-Rule:MF_00051}., Amino-acid biosynthesis, glycine biosynthesis, glycine from L-serine: step 1/1. {ECO:0000255|HAMAP-Rule:MF_00051}.

Product Synonyms

Product (LegacyBRC)	Product (RefSeq)

Operon

Refseq

GI Number	Accession	Blast	Conserved Domains

GO Terms

GO:0005737 GO:0019264 GO:0004372 GO:0030170 GO:0035999 -

GO:0005737

GO:0019264

GO:0004372

GO:0030170

GO:0035999

String Network

Link to STRINGS	STRINGS Network
MSMEG_5249

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