21364 Peptidase_C19 superfamilyThalassiosira pseudonana
GO:0004197 GO:0004221 GO:0006511 -
cysteine-type endopeptidase activity
Catalysis of the hydrolysis of internal, alpha-peptide bonds in a polypeptide chain by a mechanism in which the sulfhydryl group of a cysteine residue at the active center acts as a nucleophile.
ubiquitin thiolesterase activity
Catalysis of the reaction: ubiquitin C-terminal thioester + H2O = ubiquitin + a thiol.
ubiquitin-dependent protein catabolic process
The chemical reactions and pathways resulting in the breakdown of a protein or peptide by hydrolysis of its peptide bonds, initiated by the covalent attachment of a ubiquitin group, or multiple ubiquitin groups, to the protein.