268868 (ERCC2) rad3
Thalassiosira pseudonana

Genome Browser

Summary

Chromosome Product Transcript Start End Strand Short Name
268868 chr_5 (ERCC2) rad3 716244 718918 + rad3

Synonyms

NCBI ID Ensembl Genomes exon ID
7446424 Thaps268868.3, Thaps268868.2, Thaps268868.1, Thaps268868.4

Hierarchical Clustering

Expression Profile Conditional Changes Cluster Dendrogram
Thaps_hclust_0172

Most Highly Correlated Transcripts

261400

NA
0.937

16295

FBPase
0.9201

260890

MAD
0.9197

268338

(FAO1) fadB
0.9192

11998

hypothetical protein
0.9166

30701

PRK05279
0.9163

262976

PDEase_I
0.9157

36494

NBD_sugar-kinase_HSP70_actin superfamily
0.9148

31160

Sec3_C superfamily
0.9137

17582

HAD-SF-IIA-hyp3
0.9133

Conserved Domains

Name CD Accession Definition Superfamily Bitscore E-Value From - To Hit Type PSSM ID
DEXDc superfamily DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA... - 283.115 1.36E-88 8 - 285 superfamily 266587
DUF1227 superfamily Protein of unknown function (DUF1227); This family represents a conserved region within a number of... - 189.766 2.69E-56 273 - 425 superfamily 191608
DUF1227 superfamily Protein of unknown function (DUF1227); This family represents a conserved region within a number of... - 189.766 2.69E-56 273 - 425 superfamily 191608
HELICc2 helicase superfamily c-terminal domain; helicase superfamily c-terminal domain. cl17460 171.693 5.92E-50 557 - 701 specific 214694
Helicase_C_2 superfamily Helicase C-terminal domain; This domain is the second of two tandem AAA domains found in a wide... - 171.693 5.92E-50 557 - 701 superfamily 266701
rad3 DNA repair helicase (rad3); All proteins in this family for which funcitons are known are DNA-DNA... - 762.72 0 7 - 723 multi-dom 233047

Homologs in Other Species

T. pseudonana P. tricornutum P. tricornutum DiatomCyc F. cylindrus Pseudo-nitzschia multiseries E. huxleyi C. reinhardtii A. thaliana P. sojae
Not available PHATRDRAFT_54072 PHATRDRAFT_54072 201859 210123 63180 Cre17.g706300.t1.1 AT1G03190.2 354695

KEGG

KEGG description KEGG Pathway
Nucleotide excision repair map03420

GO Terms

GO:0003677 GO:0004003 GO:0005524 GO:0005634 GO:0006289 GO:0016818 GO:0003676 GO:0008026 GO:0006139 GO:0000810 GO:0004787 GO:0008722 GO:0008758 GO:0008796 GO:0008828 GO:0016462 GO:0019176 GO:0019177 -

GO:0003677

DNA binding

Details: 
Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid).
GO Category: 
MF

GO:0004003

ATP-dependent DNA helicase activity

Details: 
Catalysis of the reaction: ATP + H2O = ADP + phosphate; this reaction drives the unwinding of the DNA helix.
GO Category: 
MF

GO:0005524

ATP binding

Details: 
Interacting selectively and non-covalently with ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
GO Category: 
MF

GO:0005634

nucleus

Details: 
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
GO Category: 
CC

GO:0006289

nucleotide-excision repair

Details: 
A DNA repair process in which a small region of the strand surrounding the damage is removed from the DNA helix as an oligonucleotide. The small gap left in the DNA helix is filled in by the sequential action of DNA polymerase and DNA ligase. Nucleotide excision repair recognizes a wide range of substrates, including damage caused by UV irradiation (pyrimidine dimers and 6-4 photoproducts) and chemicals (intrastrand cross-links and bulky adducts).
GO Category: 
BP

GO:0016818

hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides

Details: 
Catalysis of the hydrolysis of any acid anhydride which contains phosphorus.
GO Category: 
MF

GO:0003676

nucleic acid binding

Details: 
Interacting selectively and non-covalently with any nucleic acid.
GO Category: 
MF

GO:0008026

ATP-dependent helicase activity

Details: 
Catalysis of the reaction: ATP + H2O = ADP + phosphate, to drive the unwinding of a DNA or RNA helix.
GO Category: 
MF

GO:0006139

nucleobase-containing compound metabolic process

Details: 
Any cellular metabolic process involving nucleobases, nucleosides, nucleotides and nucleic acids.
GO Category: 
BP

GO:0000810

diacylglycerol diphosphate phosphatase activity

Details: 
Catalysis of the reaction: a 1,2-diacyl-sn-glycerol 3-diphosphate + H2O = a 1,2-diacyl-sn-glycerol 3-phosphate + phosphate.
GO Category: 
MF

GO:0004787

thiamine-pyrophosphatase activity

Details: 
Catalysis of the reaction: TDP + H2O = TMP + phosphate.
GO Category: 
MF

GO:0008722

NA

Details: 
NA
GO Category: 
NA

GO:0008758

UDP-2,3-diacylglucosamine hydrolase activity

Details: 
Catalysis of the reaction: H2O + UDP-2,3-bis(3-hydroxymyristoyl)glucosamine = 2,3-bis(3-hydroxymyristoyl)-beta-D-glucosaminyl 1-phosphate + UMP.
GO Category: 
MF

GO:0008796

bis(5'-nucleosyl)-tetraphosphatase activity

Details: 
Catalysis of the hydrolysis of P(1),P(4)-bis(5'-nucleosyl)tetraphosphate into two nucleotides.
GO Category: 
MF

GO:0008828

dATP pyrophosphohydrolase activity

Details: 
Catalysis of the reaction: deoxy-ATP + H2O = dAMP + diphosphate.
GO Category: 
MF

GO:0016462

pyrophosphatase activity

Details: 
Catalysis of the hydrolysis of a pyrophosphate bond between two phosphate groups, leaving one phosphate on each of the two fragments.
GO Category: 
MF

GO:0019176

dihydroneopterin monophosphate phosphatase activity

Details: 
Catalysis of the reaction: dihydroneopterin monophosphate = dihydroneopterin + phosphate.
GO Category: 
MF

GO:0019177

dihydroneopterin triphosphate pyrophosphohydrolase activity

Details: 
Catalysis of the reaction: dihydroneopterin triphosphate = dihydroneopterin phosphate + diphosphate.
GO Category: 
MF

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