GO:0004663

Rab geranylgeranyltransferase activity

Details: 
Catalysis of the reaction: 2 geranylgeranyl diphosphate + protein-cysteine = 2 S-geranylgeranyl-protein + 2 diphosphate. This reaction is the formation of two thioether linkages between the C-1 atom of the geranylgeranyl groups and two cysteine residues within the terminal sequence motifs XXCC, XCXC or CCXX. Known substrates include Ras-related GTPases of a single family and the Rab family.
GO Category: 
MF
Trans_IPPS_HT
PT_UbiA_COQ2
(GGPS5) Trans_IPPS_HT
Trans_IPPS_HH
(GGTB1) PLN03201
FTase
BET4
PT_UbiA_Cox10