ESC/E(Z) complex

id: GO:0035098
name: ESC/E(Z) complex
namespace: cellular_component
type: go
obsolete: False

Description: A multimeric protein complex that can methylate lysine-27 and lysine-9 residues of histone H3. In Drosophila the core subunits of the complex include ESC, E(Z), CAF1 (NURF-55) and SU(Z)12. In mammals the core subunits of the complex include EED, EZH2, SUZ12 and RBBP4.

Parent Functions

idname
GO:0031519PcG protein complex
GO:0035097histone methyltransferase complex