canonical Wnt receptor signaling pathway

id: GO:0060070
name: canonical Wnt receptor signaling pathway
namespace: biological_process
type: go
obsolete: False

Description: The series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes. In this pathway, the activated receptor signals via downstream effectors that result in the inhibition of beta-catenin phosphorylation, thereby preventing degradation of beta-catenin. Stabilized beta-catenin can then accumulate and travel to the nucleus to trigger changes in transcription of target genes.

Child Functions

idname
GO:0044328canonical Wnt receptor signaling pathway involved in positive regulation of endothelial cell migration
GO:0044329canonical Wnt receptor signaling pathway involved in positive regulation of cell-cell adhesion
GO:0044330canonical Wnt receptor signaling pathway involved in positive regulation of wound healing
GO:0044334canonical Wnt receptor signaling pathway involved in positive regulation of epithelial to mesenchymal transition
GO:0044335canonical Wnt receptor signaling pathway involved in neural crest cell differentiation
GO:0044336canonical Wnt receptor signaling pathway involved in negative regulation of apoptosis
GO:0044337canonical Wnt receptor signaling pathway involved in positive regulation of apoptosis
GO:0044338canonical Wnt receptor signaling pathway involved in mesenchymal stem cell differentiation
GO:0044339canonical Wnt receptor signaling pathway involved in osteoblast differentiation
GO:0044340canonical Wnt receptor signaling pathway involved in regulation of cell proliferation
GO:0060823canonical Wnt receptor signaling pathway involved in neural plate anterior/posterior pattern formation
GO:0060901regulation of hair cycle by canonical Wnt receptor signaling pathway
GO:0061290canonical Wnt receptor signaling pathway involved in metanephric kidney development
GO:0061292canonical Wnt receptor signaling pathway involved in mesonephros development
GO:0061316canonical Wnt receptor signaling pathway involved in heart development

Parent Functions

idname
GO:0016055Wnt receptor signaling pathway