GO:0004407

histone deacetylase activity

Details: 
Catalysis of the reaction: histone N6-acetyl-L-lysine + H2O = histone L-lysine + acetate. This reaction represents the removal of an acetyl group from a histone, a class of proteins complexed to DNA in chromatin and chromosomes. [EC:3.5.1.-, PMID:9893272]
Evidence Code: