Module 56 Residual: 0.52

Title Bicluster Model Residual Score
bicluster_0056 v02 0.52 -5.81
Displaying 1 - 14 of 14
Rv0058 Replicative DNA helicase (EC 3.6.1.-) @ intein-containing

Details for Rv0058 - Replicative DNA helicase (EC 3.6.1.-) @ intein-containing

GO Terms: GO:0005618, GO:0005829, GO:0006974, GO:0040007

PATRIC Pathways: Lipopolysaccharide biosynthesis, Purine metabolism, Folate biosynthesis

Essentiality: Griffin Essential: 0.00 | In vitro Essential: 0.07 | In vivo Essential: NA

Go to Gene Page: Rv0058

Tuberculist Genomic Region

Rv0361 PROBABLE CONSERVED MEMBRANE PROTEIN

Details for Rv0361 - PROBABLE CONSERVED MEMBRANE PROTEIN

GO Terms: GO:0005887

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.63 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv0361

Tuberculist Genomic Region

Rv1821 Protein export cytoplasm protein SecA ATPase RNA helicase (TC 3.A.5.1.1)

Details for Rv1821 - Protein export cytoplasm protein SecA ATPase RNA helicase (TC 3.A.5.1.1)

GO Terms: GO:0005515, GO:0003676, GO:0017038, GO:0016020, GO:0005524, GO:0004386, GO:0005886, GO:0009405, GO:0016887, GO:0043952, GO:0044119, GO:0052553

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.00 | In vitro Essential: NA | In vivo Essential: 0.19

Go to Gene Page: Rv1821

Tuberculist Genomic Region

Rv2453c Molybdopterin-guanine dinucleotide biosynthesis protein MobA

Details for Rv2453c - Molybdopterin-guanine dinucleotide biosynthesis protein MobA

GO Terms: GO:0005886

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.78 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv2453c

Tuberculist Genomic Region

Rv2454c 2-oxoglutarate oxidoreductase, beta subunit (EC 1.2.7.3)

Details for Rv2454c - 2-oxoglutarate oxidoreductase, beta subunit (EC 1.2.7.3)

GO Terms: GO:0047553, GO:0000287, GO:0005618, GO:0005829, GO:0047553

PATRIC Pathways: Citrate cycle (TCA cycle), Reductive carboxylate cycle (CO2 fixation)

Essentiality: Griffin Essential: 0.00 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv2454c

Tuberculist Genomic Region

Rv2455c 2-oxoglutarate oxidoreductase, alpha subunit (EC 1.2.7.3)

Details for Rv2455c - 2-oxoglutarate oxidoreductase, alpha subunit (EC 1.2.7.3)

GO Terms: GO:0047553, GO:0005886

PATRIC Pathways: Reductive carboxylate cycle (CO2 fixation), Citrate cycle (TCA cycle)

Essentiality: Griffin Essential: 0.00 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv2455c

Tuberculist Genomic Region

Rv2734 Phage Gp37Gp68 protein

Details for Rv2734 - Phage Gp37Gp68 protein

GO Terms: GO:0005886

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.08 | In vitro Essential: NA | In vivo Essential: 0.25

Go to Gene Page: Rv2734

Tuberculist Genomic Region

Rv3035

Details for Rv3035 -

GO Terms: NA

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.00 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv3035

Tuberculist Genomic Region

Rv3198c ATP-dependent DNA helicase UvrD/PcrA, actinomycete paralog

Details for Rv3198c - ATP-dependent DNA helicase UvrD/PcrA, actinomycete paralog

GO Terms: GO:0004003, GO:0005524, GO:0006281, GO:0003677, GO:0000287, GO:0003678, GO:0008094, GO:0040007

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.00 | In vitro Essential: 0.13 | In vivo Essential: NA

Go to Gene Page: Rv3198c

Tuberculist Genomic Region

Rv3913 Thioredoxin reductase (EC 1.8.1.9)

Details for Rv3913 - Thioredoxin reductase (EC 1.8.1.9)

GO Terms: GO:0004791, GO:0001666, GO:0004791, GO:0040007, GO:0042803, GO:0045454, GO:0050660, GO:0070402

PATRIC Pathways: Selenoamino acid metabolism, Pyrimidine metabolism

Essentiality: Griffin Essential: 0.00 | In vitro Essential: 0.07 | In vivo Essential: NA

Go to Gene Page: Rv3913

Tuberculist Genomic Region

Rv3914 Thioredoxin reductase (EC 1.8.1.9)

Details for Rv3914 - Thioredoxin reductase (EC 1.8.1.9)

GO Terms: GO:0005576, GO:0005829, GO:0005886, GO:0009055, GO:0015035, GO:0045454

PATRIC Pathways: Selenoamino acid metabolism, Pyrimidine metabolism

Essentiality: Griffin Essential: 0.09 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv3914

Tuberculist Genomic Region

Rv2732c Possible membrane protein

Details for Rv2732c - Possible membrane protein

GO Terms: NA

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.53 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv2732c

Tuberculist Genomic Region

Rv2733c tRNA-i(6)A37 methylthiotransferase

Details for Rv2733c - tRNA-i(6)A37 methylthiotransferase

GO Terms: GO:0003824, GO:0005506

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.98 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv2733c

Tuberculist Genomic Region

Rv2855 NADPH-dependent mycothiol reductase Mtr

Details for Rv2855 - NADPH-dependent mycothiol reductase Mtr

GO Terms: GO:0040007, GO:0042803, GO:0050627, GO:0050660, GO:0055114, GO:0070402

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.06 | In vitro Essential: 0.17 | In vivo Essential: NA

Go to Gene Page: Rv2855

Tuberculist Genomic Region

Displaying 1 - 1 of 1
Motif 1 Motif 2
e-value: 0.11 e-value: 16000
Displaying 1 - 1 of 1
Module GO Term Enrichment Descriptions
GO:0016667 | GO:0004386 | GO:0016668 oxidoreductase activity, acting on a sul... | helicase activity | oxidoreductase activity, acting on a sul...
Displaying 1 - 38 of 38
GO:0005618 |

cell wall

GO:0005829 |

cytosol

GO:0006974 |

response to DNA damage stimulus

GO:0040007 |

growth

GO:0005887 |

integral to plasma membrane

GO:0005515 |

protein binding

GO:0003676 |

nucleic acid binding

GO:0017038 |

protein import

GO:0016020 |

membrane

GO:0005524 |

ATP binding

GO:0004386 |

helicase activity

GO:0005886 |

plasma membrane

GO:0009405 |

pathogenesis

GO:0016887 |

ATPase activity

GO:0043952 |

protein transport by the Sec complex

GO:0044119 |

growth of symbiont in host cell

GO:0052553 |

modulation by symbiont of host immune response

GO:0047553 |

2-oxoglutarate synthase activity

GO:0000287 |

magnesium ion binding

GO:0004003 |

ATP-dependent DNA helicase activity

GO:0006281 |

DNA repair

GO:0003677 |

DNA binding

GO:0003678 |

DNA helicase activity

GO:0008094 |

DNA-dependent ATPase activity

GO:0004791 |

thioredoxin-disulfide reductase activity

GO:0001666 |

response to hypoxia

GO:0042803 |

protein homodimerization activity

GO:0045454 |

cell redox homeostasis

GO:0050660 |

flavin adenine dinucleotide binding

GO:0070402 |

NADPH binding

GO:0005576 |

extracellular region

GO:0009055 |

electron carrier activity

GO:0015035 |

protein disulfide oxidoreductase activity

GO:0003824 |

catalytic activity

GO:0005506 |

iron ion binding

GO:0050627 |

mycothione reductase activity

GO:0055114 |

oxidation-reduction process