Module 145 Residual: 0.56

Title Bicluster Model Residual Score
bicluster_0145 v02 0.56 -16.64
Displaying 1 - 16 of 16
Rv0944 Formamidopyrimidine-DNA glycosylase (EC 3.2.2.23)

Details for Rv0944 - Formamidopyrimidine-DNA glycosylase (EC 3.2.2.23)

GO Terms: GO:0004519, GO:0005886, GO:0006281, GO:0006289, GO:0034599

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.68 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv0944

Tuberculist Genomic Region

Rv0945 Oxidoreductase, short-chain dehydrogenase/reductase family (EC 1.1.1.-)
Rv0955 FIG021574: Possible membrane protein related to de Novo purine biosynthesis

Details for Rv0955 - FIG021574: Possible membrane protein related to de Novo purine biosynthesis

GO Terms: GO:0040007

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.00 | In vitro Essential: 0.04 | In vivo Essential: NA

Go to Gene Page: Rv0955

Tuberculist Genomic Region

Rv1010 Dimethyladenosine transferase (EC 2.1.1.-)

Details for Rv1010 - Dimethyladenosine transferase (EC 2.1.1.-)

GO Terms: GO:0008649, GO:0000154

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.17 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv1010

Tuberculist Genomic Region

Rv1415 3,4-dihydroxy-2-butanone 4-phosphate synthase / GTP cyclohydrolase II (EC 3.5.4.25)

Details for Rv1415 - 3,4-dihydroxy-2-butanone 4-phosphate synthase / GTP cyclohydrolase II (EC 3.5.4.25)

GO Terms: GO:0005576, GO:0040007

PATRIC Pathways: Riboflavin metabolism, Riboflavin metabolism

Essentiality: Griffin Essential: 0.00 | In vitro Essential: 0.17 | In vivo Essential: NA

Go to Gene Page: Rv1415

Tuberculist Genomic Region

Rv1416 6,7-dimethyl-8-ribityllumazine synthase (EC 2.5.1.78)

Details for Rv1416 - 6,7-dimethyl-8-ribityllumazine synthase (EC 2.5.1.78)

GO Terms: GO:0004746, GO:0040007

PATRIC Pathways: Riboflavin metabolism

Essentiality: Griffin Essential: 0.12 | In vitro Essential: 0.04 | In vivo Essential: NA

Go to Gene Page: Rv1416

Tuberculist Genomic Region

Rv1417 Cell division protein DivIC (FtsB), stabilizes FtsL against RasP cleavage

Details for Rv1417 - Cell division protein DivIC (FtsB), stabilizes FtsL against RasP cleavage

GO Terms: GO:0005886

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.12 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv1417

Tuberculist Genomic Region

Rv1897c D-tyrosyl-tRNA(Tyr) deacylase

Details for Rv1897c - D-tyrosyl-tRNA(Tyr) deacylase

GO Terms: GO:0019478, GO:0005737

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.71 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv1897c

Tuberculist Genomic Region

Rv1898 ExtraCellular Mutant; Ecm15p

Details for Rv1898 - ExtraCellular Mutant; Ecm15p

GO Terms: NA

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.63 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv1898

Tuberculist Genomic Region

Rv2772c

Details for Rv2772c -

GO Terms: NA

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.75 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv2772c

Tuberculist Genomic Region

Rv2849c Cob(I)alamin adenosyltransferase (EC 2.5.1.17)

Details for Rv2849c - Cob(I)alamin adenosyltransferase (EC 2.5.1.17)

GO Terms: GO:0008817

PATRIC Pathways: Porphyrin and chlorophyll metabolism

Essentiality: Griffin Essential: 0.32 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv2849c

Tuberculist Genomic Region

Rv2850c ChlI component of cobalt chelatase involved in B12 biosynthesis / ChlD component of cobalt chelatase involved in B12 biosynthesis

Details for Rv2850c - ChlI component of cobalt chelatase involved in B12 biosynthesis / ChlD component of cobalt chelatase involved in B12 biosynthesis

GO Terms: NA

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.13 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv2850c

Tuberculist Genomic Region

Rv3592 Antibiotic biosynthesis monooxygenase

Details for Rv3592 - Antibiotic biosynthesis monooxygenase

GO Terms: GO:0005886

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.53 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv3592

Tuberculist Genomic Region

Rv3593 Beta-lactamase (EC 3.5.2.6)

Details for Rv3593 - Beta-lactamase (EC 3.5.2.6)

GO Terms: GO:0040007

PATRIC Pathways: beta-Lactam resistance, Penicillin and cephalosporin biosynthesis

Essentiality: Griffin Essential: 0.00 | In vitro Essential: 0.10 | In vivo Essential: NA

Go to Gene Page: Rv3593

Tuberculist Genomic Region

Rv0953c Hydride transferase 1 (Fragment)

Details for Rv0953c - Hydride transferase 1 (Fragment)

GO Terms: NA

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.97 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv0953c

Tuberculist Genomic Region

Rv0954 antigen 34 kDa

Details for Rv0954 - antigen 34 kDa

GO Terms: GO:0005887

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.60 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv0954

Tuberculist Genomic Region

Displaying 1 - 1 of 1
Motif 1 Motif 2
e-value: 0.00077 e-value: 0.16
Displaying 1 - 1 of 1
Module GO Term Enrichment Descriptions
GO:0006771 | GO:0009231 | GO:0042726 | GO:0042727 riboflavin metabolic process | riboflavin biosynthetic process | flavin-containing compound metabolic pro... | flavin-containing compound biosynthetic ...
Displaying 1 - 15 of 15
GO:0004519 |

endonuclease activity

GO:0005886 |

plasma membrane

GO:0006281 |

DNA repair

GO:0006289 |

nucleotide-excision repair

GO:0034599 |

cellular response to oxidative stress

GO:0040007 |

growth

GO:0008649 |

rRNA methyltransferase activity

GO:0000154 |

rRNA modification

GO:0005576 |

extracellular region

GO:0004746 |

riboflavin synthase activity

GO:0019478 |

D-amino acid catabolic process

GO:0005737 |

cytoplasm

GO:0008817 |

cob(I)yrinic acid a,c-diamide adenosyltransferase activity

GO:0005887 |

integral to plasma membrane