Module 236 Residual: 0.53

Title Bicluster Model Residual Score
bicluster_0236 v02 0.53 -11.19
Displaying 1 - 19 of 19
Rv0239

Details for Rv0239 -

GO Terms: NA

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.63 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv0239

Tuberculist Genomic Region

Rv0240

Details for Rv0240 -

GO Terms: GO:0005886

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.68 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv0240

Tuberculist Genomic Region

Rv0788 Phosphoribosylformylglycinamidine synthase, glutamine amidotransferase subunit (EC 6.3.5.3)

Details for Rv0788 - Phosphoribosylformylglycinamidine synthase, glutamine amidotransferase subunit (EC 6.3.5.3)

GO Terms: GO:0004642, GO:0005886, GO:0040007

PATRIC Pathways: Purine metabolism

Essentiality: Griffin Essential: 0.00 | In vitro Essential: 0.08 | In vivo Essential: NA

Go to Gene Page: Rv0788

Tuberculist Genomic Region

Rv1100

Details for Rv1100 -

GO Terms: NA

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.72 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv1100

Tuberculist Genomic Region

Rv1178 N-succinyl-L,L-diaminopimelate aminotransferase alternative (EC 2.6.1.17)

Details for Rv1178 - N-succinyl-L,L-diaminopimelate aminotransferase alternative (EC 2.6.1.17)

GO Terms: GO:0009016, GO:0005886

PATRIC Pathways: Lysine biosynthesis

Essentiality: Griffin Essential: 0.73 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv1178

Tuberculist Genomic Region

Rv1479 COG0714: MoxR-like ATPases

Details for Rv1479 - COG0714: MoxR-like ATPases

GO Terms: GO:0005618, GO:0005886, GO:0040007

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.00 | In vitro Essential: 0.09 | In vivo Essential: NA

Go to Gene Page: Rv1479

Tuberculist Genomic Region

Rv1480 Possible membrane protein

Details for Rv1480 - Possible membrane protein

GO Terms: GO:0005829, GO:0005886, GO:0040007

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.09 | In vitro Essential: 0.05 | In vivo Essential: NA

Go to Gene Page: Rv1480

Tuberculist Genomic Region

Rv2109c Proteasome subunit alpha (EC 3.4.25.1), bacterial

Details for Rv2109c - Proteasome subunit alpha (EC 3.4.25.1), bacterial

GO Terms: GO:0005515, GO:0005618, GO:0005886, GO:0040007, GO:0051603

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.00 | In vitro Essential: 0.09 | In vivo Essential: NA

Go to Gene Page: Rv2109c

Tuberculist Genomic Region

Rv2110c Proteasome subunit beta (EC 3.4.25.1), bacterial

Details for Rv2110c - Proteasome subunit beta (EC 3.4.25.1), bacterial

GO Terms: GO:0005515, GO:0005576, GO:0005886, GO:0040007, GO:0051603

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.00 | In vitro Essential: 0.09 | In vivo Essential: NA

Go to Gene Page: Rv2110c

Tuberculist Genomic Region

Rv2111c Prokaryotic ubiquitin-like protein Pup

Details for Rv2111c - Prokaryotic ubiquitin-like protein Pup

GO Terms: GO:0005515, GO:0040007, GO:0070490

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.22 | In vitro Essential: 0.09 | In vivo Essential: NA

Go to Gene Page: Rv2111c

Tuberculist Genomic Region

Rv2112c Pup ligase PafA' paralog, possible component of postulated heterodimer PafA-PafA'

Details for Rv2112c - Pup ligase PafA' paralog, possible component of postulated heterodimer PafA-PafA'

GO Terms: GO:0005515, GO:0005524, GO:0016811, GO:0070490

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.00 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv2112c

Tuberculist Genomic Region

Rv2254c Possible membrane protein

Details for Rv2254c - Possible membrane protein

GO Terms: NA

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.53 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv2254c

Tuberculist Genomic Region

Rv2255c

Details for Rv2255c -

GO Terms: NA

PATRIC Pathways: NA

Essentiality: Griffin Essential: 0.63 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv2255c

Tuberculist Genomic Region

Rv2583c GTP pyrophosphokinase (EC 2.7.6.5), (p)ppGpp synthetase I

Details for Rv2583c - GTP pyrophosphokinase (EC 2.7.6.5), (p)ppGpp synthetase I

GO Terms: GO:0005618, GO:0005886, GO:0008728, GO:0008893, GO:0009405, GO:0015968, GO:0030145

PATRIC Pathways: Purine metabolism

Essentiality: Griffin Essential: 0.00 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv2583c

Tuberculist Genomic Region

Rv2675c Methyltransferase (EC 2.1.1.-) colocalized with Q
Rv2676c Hemoprotein HemQ, essential component of heme biosynthetic pathway in Gram-positive bacteria

Details for Rv2676c - Hemoprotein HemQ, essential component of heme biosynthetic pathway in Gram-positive bacteria

GO Terms: GO:0005886

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.00 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv2676c

Tuberculist Genomic Region

Rv2677c Protoporphyrinogen IX oxidase, aerobic (EC 1.3.3.4)

Details for Rv2677c - Protoporphyrinogen IX oxidase, aerobic (EC 1.3.3.4)

GO Terms: GO:0004729

PATRIC Pathways: Porphyrin and chlorophyll metabolism

Essentiality: Griffin Essential: 0.00 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv2677c

Tuberculist Genomic Region

Rv2678c Uroporphyrinogen III decarboxylase (EC 4.1.1.37)

Details for Rv2678c - Uroporphyrinogen III decarboxylase (EC 4.1.1.37)

GO Terms: GO:0004853, GO:0005829

PATRIC Pathways: Porphyrin and chlorophyll metabolism

Essentiality: Griffin Essential: 0.00 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv2678c

Tuberculist Genomic Region

Rv1481 Possible membrane protein

Details for Rv1481 - Possible membrane protein

GO Terms: GO:0005886, GO:0005887

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.00 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv1481

Tuberculist Genomic Region

Displaying 1 - 1 of 1
Motif 1 Motif 2
e-value: 1500 e-value: 1800
Displaying 1 - 1 of 1
Module GO Term Enrichment Descriptions
GO:0044265 | GO:0033013 | GO:0033014 | GO:0006778 | GO:0006779 cellular macromolecule catabolic process | tetrapyrrole metabolic process | tetrapyrrole biosynthetic process | porphyrin-containing compound metabolic ... | porphyrin-containing compound biosynthet...
Displaying 1 - 21 of 21
GO:0005886 |

plasma membrane

GO:0004642 |

phosphoribosylformylglycinamidine synthase activity

GO:0040007 |

growth

GO:0009016 |

succinyldiaminopimelate transaminase activity

GO:0005618 |

cell wall

GO:0005829 |

cytosol

GO:0005515 |

protein binding

GO:0051603 |

proteolysis involved in cellular protein catabolic process

GO:0005576 |

extracellular region

GO:0070490 |

protein pupylation

GO:0005524 |

ATP binding

GO:0016811 |

hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides

GO:0008728 |

GTP diphosphokinase activity

GO:0008893 |

guanosine-3',5'-bis(diphosphate) 3'-diphosphatase activity

GO:0009405 |

pathogenesis

GO:0015968 |

stringent response

GO:0030145 |

manganese ion binding

GO:0004729 |

oxygen-dependent protoporphyrinogen oxidase activity

GO:0004853 |

uroporphyrinogen decarboxylase activity

GO:0005887 |

integral to plasma membrane