Module 401 Residual: 0.58

Title Bicluster Model Residual Score
bicluster_0401 v02 0.58 -9.95
Displaying 1 - 19 of 19
Rv0747 PE-PGRS FAMILY PROTEIN

Details for Rv0747 - PE-PGRS FAMILY PROTEIN

GO Terms: NA

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.88 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv0747

Tuberculist Genomic Region

Rv0916c PE family protein

Details for Rv0916c - PE family protein

GO Terms: NA

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.53 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv0916c

Tuberculist Genomic Region

Rv2638 Anti-sigma F factor antagonist (spoIIAA-2); Anti-sigma B factor antagonist RsbV

Details for Rv2638 - Anti-sigma F factor antagonist (spoIIAA-2); Anti-sigma B factor antagonist RsbV

GO Terms: GO:0005515, GO:0005886

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.71 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv2638

Tuberculist Genomic Region

Rv3122

Details for Rv3122 -

GO Terms: NA

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.63 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv3122

Tuberculist Genomic Region

Rv3123

Details for Rv3123 -

GO Terms: NA

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.71 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv3123

Tuberculist Genomic Region

Rv3288c Putative uncharacterized protein usfY

Details for Rv3288c - Putative uncharacterized protein usfY

GO Terms: NA

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.94 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv3288c

Tuberculist Genomic Region

Rv0516c Anti-sigma F factor antagonist (spoIIAA-2); Anti-sigma B factor antagonist RsbV

Details for Rv0516c - Anti-sigma F factor antagonist (spoIIAA-2); Anti-sigma B factor antagonist RsbV

GO Terms: GO:0005515

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.90 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv0516c

Tuberculist Genomic Region

Rv0751c 3-hydroxyisobutyrate dehydrogenase (EC 1.1.1.31)

Details for Rv0751c - 3-hydroxyisobutyrate dehydrogenase (EC 1.1.1.31)

GO Terms: GO:0008442

PATRIC Pathways: Valine, leucine and isoleucine degradation

Essentiality: Griffin Essential: 0.87 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv0751c

Tuberculist Genomic Region

Rv0753c Methylmalonate-semialdehyde dehydrogenase (EC 1.2.1.27)

Details for Rv0753c - Methylmalonate-semialdehyde dehydrogenase (EC 1.2.1.27)

GO Terms: GO:0004491, GO:0005886

PATRIC Pathways: Propanoate metabolism, Inositol phosphate metabolism, Valine, leucine and isoleucine degradation

Essentiality: Griffin Essential: 0.99 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv0753c

Tuberculist Genomic Region

Rv1187 Delta-1-pyrroline-5-carboxylate dehydrogenase (EC 1.5.1.12)

Details for Rv1187 - Delta-1-pyrroline-5-carboxylate dehydrogenase (EC 1.5.1.12)

GO Terms: GO:0003842, GO:0040007

PATRIC Pathways: Arginine and proline metabolism, Alanine, aspartate and glutamate metabolism

Essentiality: Griffin Essential: 0.01 | In vitro Essential: 0.19 | In vivo Essential: NA

Go to Gene Page: Rv1187

Tuberculist Genomic Region

Rv1991c

Details for Rv1991c -

GO Terms: GO:0008150, GO:0008150, GO:0004540, GO:0006402, GO:0045926, GO:0045927

PATRIC Pathways: NA

Essentiality: Griffin Essential: 0.95 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv1991c

Tuberculist Genomic Region

Rv1992c Lead, cadmium, zinc and mercury transporting ATPase (EC 3.6.3.3) (EC 3.6.3.5); Copper-translocating P-type ATPase (EC 3.6.3.4)

Details for Rv1992c - Lead, cadmium, zinc and mercury transporting ATPase (EC 3.6.3.3) (EC 3.6.3.5); Copper-translocating P-type ATPase (EC 3.6.3.4)

GO Terms: GO:0005886, GO:0005887

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.99 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv1992c

Tuberculist Genomic Region

Rv1993c

Details for Rv1993c -

GO Terms: GO:0005886

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.71 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv1993c

Tuberculist Genomic Region

Rv2660c

Details for Rv2660c -

GO Terms: NA

PATRIC Pathways: NA

Essentiality: Griffin Essential: 0.47 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv2660c

Tuberculist Genomic Region

Rv2661c

Details for Rv2661c -

GO Terms: NA

PATRIC Pathways: NA

Essentiality: Griffin Essential: 0.63 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv2661c

Tuberculist Genomic Region

Rv2663

Details for Rv2663 -

GO Terms: NA

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.92 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv2663

Tuberculist Genomic Region

Rv3286c RNA polymerase sigma factor SigB

Details for Rv3286c - RNA polymerase sigma factor SigB

GO Terms: GO:0016987, GO:0003700, GO:0006352, GO:0003677, GO:0005515, GO:0006351, GO:0006629, GO:0006979, GO:0006995, GO:0009409, GO:0016987, GO:0034059, GO:0043175, GO:0045893, GO:0046677, GO:0052572, GO:0070417

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.95 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv3286c

Tuberculist Genomic Region

Rv3287c Serine-protein kinase RsbW (EC 2.7.11.1)

Details for Rv3287c - Serine-protein kinase RsbW (EC 2.7.11.1)

GO Terms: GO:0000166, GO:0005515, GO:0016989

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.53 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv3287c

Tuberculist Genomic Region

Rv3334 Mercuric resistance operon regulatory protein

Details for Rv3334 - Mercuric resistance operon regulatory protein

GO Terms: NA

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.92 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv3334

Tuberculist Genomic Region

Displaying 1 - 1 of 1
Motif 1 Motif 2
e-value: 100 e-value: 180
Displaying 1 - 1 of 1
Module GO Term Enrichment Descriptions
No enrichment
Displaying 1 - 30 of 30
GO:0005515 |

protein binding

GO:0005886 |

plasma membrane

GO:0008442 |

3-hydroxyisobutyrate dehydrogenase activity

GO:0004491 |

methylmalonate-semialdehyde dehydrogenase (acylating) activity

GO:0003842 |

1-pyrroline-5-carboxylate dehydrogenase activity

GO:0040007 |

growth

GO:0008150 |

biological_process

GO:0004540 |

ribonuclease activity

GO:0006402 |

mRNA catabolic process

GO:0045926 |

negative regulation of growth

GO:0045927 |

positive regulation of growth

GO:0005887 |

integral to plasma membrane

GO:0016987 |

sigma factor activity

GO:0003700 |

sequence-specific DNA binding transcription factor activity

GO:0006352 |

DNA-dependent transcription, initiation

GO:0003677 |

DNA binding

GO:0006351 |

transcription, DNA-dependent

GO:0006629 |

lipid metabolic process

GO:0006979 |

response to oxidative stress

GO:0006995 |

cellular response to nitrogen starvation

GO:0009409 |

response to cold

GO:0034059 |

response to anoxia

GO:0043175 |

RNA polymerase core enzyme binding

GO:0045893 |

positive regulation of transcription, DNA-dependent

GO:0046677 |

response to antibiotic

GO:0052572 |

response to host immune response

GO:0070417 |

cellular response to cold

GO:0000166 |

nucleotide binding

GO:0016989 |

sigma factor antagonist activity