Module 556 Residual: 0.55

Title Bicluster Model Residual Score
bicluster_0556 v02 0.55 -15.48
Displaying 1 - 12 of 12
Rv2068c Beta-lactamase class A

Details for Rv2068c - Beta-lactamase class A

GO Terms: GO:0005576, GO:0005886, GO:0008800, GO:0030655, GO:0033250, GO:0033251, GO:0046677

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.98 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv2068c

Tuberculist Genomic Region

Rv2069 RNA polymerase sigma-54 factor RpoN

Details for Rv2069 - RNA polymerase sigma-54 factor RpoN

GO Terms: GO:0001666, GO:0009405, GO:0009408, GO:0009410, GO:0009415, GO:0006355

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.90 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv2069

Tuberculist Genomic Region

Rv2225 3-methyl-2-oxobutanoate hydroxymethyltransferase (EC 2.1.2.11)

Details for Rv2225 - 3-methyl-2-oxobutanoate hydroxymethyltransferase (EC 2.1.2.11)

GO Terms: GO:0003864, GO:0000287, GO:0003864, GO:0005886, GO:0015940, GO:0040007, GO:0051260

PATRIC Pathways: Pantothenate and CoA biosynthesis

Essentiality: Griffin Essential: 0.00 | In vitro Essential: 0.13 | In vivo Essential: NA

Go to Gene Page: Rv2225

Tuberculist Genomic Region

Rv2301 Cutinase Cut2 (EC 3.1.1.74)

Details for Rv2301 - Cutinase Cut2 (EC 3.1.1.74)

GO Terms: GO:0005576, GO:0042783

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.75 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv2301

Tuberculist Genomic Region

Rv2861c Methionine aminopeptidase (EC 3.4.11.18)

Details for Rv2861c - Methionine aminopeptidase (EC 3.4.11.18)

GO Terms: GO:0004239

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.00 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv2861c

Tuberculist Genomic Region

Rv3142c

Details for Rv3142c -

GO Terms: NA

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.92 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv3142c

Tuberculist Genomic Region

Rv3143 Probable response regulator

Details for Rv3143 - Probable response regulator

GO Terms: NA

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.27 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv3143

Tuberculist Genomic Region

Rv3600c Pantothenate kinase type III, CoaX-like (EC 2.7.1.33)

Details for Rv3600c - Pantothenate kinase type III, CoaX-like (EC 2.7.1.33)

GO Terms: GO:0004594, GO:0005886

PATRIC Pathways: Pantothenate and CoA biosynthesis

Essentiality: Griffin Essential: 0.96 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv3600c

Tuberculist Genomic Region

Rv3601c Aspartate 1-decarboxylase (EC 4.1.1.11)

Details for Rv3601c - Aspartate 1-decarboxylase (EC 4.1.1.11)

GO Terms: GO:0004068, GO:0004068, GO:0005618, GO:0005829, GO:0051289

PATRIC Pathways: beta-Alanine metabolism, Pantothenate and CoA biosynthesis

Essentiality: Griffin Essential: 0.01 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv3601c

Tuberculist Genomic Region

Rv3602c Pantoate--beta-alanine ligase (EC 6.3.2.1)

Details for Rv3602c - Pantoate--beta-alanine ligase (EC 6.3.2.1)

GO Terms: GO:0004592, GO:0000287, GO:0004592, GO:0005524, GO:0015940, GO:0019482, GO:0030145, GO:0040007, GO:0042803

PATRIC Pathways: Pantothenate and CoA biosynthesis, beta-Alanine metabolism

Essentiality: Griffin Essential: 0.00 | In vitro Essential: 0.07 | In vivo Essential: NA

Go to Gene Page: Rv3602c

Tuberculist Genomic Region

Rv3603c

Details for Rv3603c -

GO Terms: NA

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.00 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv3603c

Tuberculist Genomic Region

Rv3779

Details for Rv3779 -

GO Terms: NA

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.78 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv3779

Tuberculist Genomic Region

Displaying 1 - 1 of 1
Motif 1 Motif 2
e-value: 0.023 e-value: 1.4
Displaying 1 - 1 of 1
Module GO Term Enrichment Descriptions
GO:0031419 cobalamin binding
Displaying 1 - 31 of 31
GO:0005576 |

extracellular region

GO:0005886 |

plasma membrane

GO:0008800 |

beta-lactamase activity

GO:0030655 |

beta-lactam antibiotic catabolic process

GO:0033250 |

penicillinase activity

GO:0033251 |

cephalosporinase activity

GO:0046677 |

response to antibiotic

GO:0001666 |

response to hypoxia

GO:0009405 |

pathogenesis

GO:0009408 |

response to heat

GO:0009410 |

response to xenobiotic stimulus

GO:0009415 |

response to water stimulus

GO:0006355 |

regulation of transcription, DNA-dependent

GO:0003864 |

3-methyl-2-oxobutanoate hydroxymethyltransferase activity

GO:0000287 |

magnesium ion binding

GO:0015940 |

pantothenate biosynthetic process

GO:0040007 |

growth

GO:0051260 |

protein homooligomerization

GO:0042783 |

active evasion of host immune response

GO:0004239 |

methionyl aminopeptidase activity

GO:0004594 |

pantothenate kinase activity

GO:0004068 |

aspartate 1-decarboxylase activity

GO:0005618 |

cell wall

GO:0005829 |

cytosol

GO:0051289 |

protein homotetramerization

GO:0004592 |

pantoate-beta-alanine ligase activity

GO:0005524 |

ATP binding

GO:0019482 |

beta-alanine metabolic process

GO:0030145 |

manganese ion binding

GO:0042803 |

protein homodimerization activity