Rv0023 Transcriptional regulatory protein

Rv0023 (Transcriptional regulatory protein) is predicted to be co-regulated in modules bicluster_0304 with residual 0.58 and bicluster_0544 with residual 0.41.

This regulation is possibly mediated by two de-novo identified cis-regulatory motifs in each module with e-values , 0.36 and 78.00 for bicluster_0304 and 420.00 and 780.00 for bicluster_0544 respectively.

These modules are enriched for following go terms: cellular ketone metabolic process cellular homeostasis, homeostatic process, regulation of biological quality, electron carrier activity.

This gene is found to be for growth on cholesterol.

Mutant available?:

Displaying 71 - 80 of 174
Gene Target Differential Expression Distance Expression pvalue Type
Transcriptional regulator, TetR family
Repressed -138 -0.95 0.00000086 Antisense.TSS
Transcriptional regulator, TetR family
Repressed 55 -0.95 0.00000086 Internal.TSS
No 8 0.32 0.197407 Internal.TSS
Repressed 5 -0.68 0.0100294 CDS
PPE family protein
No 54 0.33 0.0751129 CDS
No -99 0.35 0.0928832 CDS
Type VII secretion integral membrane protein EccD
No -36 0.41 0.0000000729 Primary.TSS
Induced -117 1.62 0.000000000118 CDS
No -131 0.3 0.0263752 Primary.TSS
Transcriptional regulator, BlaI family
No 45 0.3 0.12745 Primary.TSS
not assigned to any KEGG Pathway.
No TFOE experiment results were found

TRIP log2 fold abundance change

NA
Displaying 1 - 17 of 17
Condition Count Day Doublings Fitness U.I Plots
D17I 3 17 19.15 5.13 I
D17U 3 17 19.15 9.94 U
D24I 3 24 26.60 4.70 I
D24U 3 24 26.60 9.32 U
D3I 3 3 3.83 11.63 I
D3U 3 3 3.83 11.40 U
D14I 4 14 15.63 6.26 I
D14U 4 14 15.63 9.95 U
D21I 4 21 23.23 5.32 I
D21U 4 21 23.23 9.06 U
D28I 4 28 30.61 5.55 I
D28U 4 28 30.61 8.40 U
D5I 9 5 6.00 12.32 I
D5U 17 5 6.00 12.61 U
D7I 18 7 8.14 8.45 I
D7U 19 7 8.14 11.60 U
D0U 27 0 0.00 12.35 U