Rv2857c Short-chain dehydrogenase/reductase in hypothetical Actinobacterial gene cluster
Rv2857c (Short-chain dehydrogenase/reductase in hypothetical Actinobacterial gene cluster) is predicted to be co-regulated in modules bicluster_0083 with residual 0.52 and bicluster_0177 with residual 0.50.
This regulation is possibly mediated by two de-novo identified cis-regulatory motifs in each module with e-values , 240.00 and 440.00 for bicluster_0083 and 3.10 and 110.00 for bicluster_0177 respectively.
These modules are enriched for following go terms: glutamine metabolic process glutamine metabolic process.
This gene is found to be for growth on cholesterol.
|BASS Score||Re-Annotated Start||Tuberculist Annotated Start|
|Product (LegacyBRC)||Product (RefSeq)|
|PROBABLE SHORT-CHAIN TYPE DEHYDROGENASE_REDUCTASE||short chain dehydrogenase|
|1869||- - -|
|BioCyc Gene Page||Cellular Overview Map|
reports the log2 abundance fold change of each TFI strain, relative to no induction, in absence or presence of drug, averaged across experimental replicates. Also reported are the accompanying z-scores and two-sided t-test p-values for each TFI strain under each condition. Please refer to Ma et al., 2020, Nature Microbiology for more information.