Rv3488 Transcriptional regulator, PadR family

Rv3488 (Transcriptional regulator, PadR family) is predicted to be co-regulated in modules bicluster_0247 with residual 0.41 and bicluster_0340 with residual 0.51.

This regulation is possibly mediated by two de-novo identified cis-regulatory motifs in each module with e-values , 430.00 and 9,100.00 for bicluster_0247 and 1,100.00 and 2,300.00 for bicluster_0340 respectively.

These modules are enriched for following go terms: .

This gene is found to be for growth on cholesterol.

Mutant available?:

Displaying 21 - 30 of 91
Gene Target Differential Expression Distance Expression pvalue Type
Toxin 1, PIN domain
No -54 -0.15 0.962221 CDS
Octaprenyl-diphosphate synthase (EC 2.5.1.-) / Dimethylallyltransferase (EC 2.5.1.1) / Geranyltranstransferase (farnesyldiphosphate synthase) (EC 2.5.1.10) / Geranylgeranyl pyrophosphate synthetase (EC 2.5.1.29)
No -6 0.35 0.962221 Antisense.TSS
Long-chain-fatty-acid--CoA ligase (EC 6.2.1.3)
No 40 0.19 0.962221 CDS
Dihydrolipoamide succinyltransferase component (E2) of 2-oxoglutarate dehydrogenase complex (EC 2.3.1.61) / 2-oxoglutarate dehydrogenase E1 component (EC 1.2.4.2)
No 0 0.14 0.962221 Primary.TSS
Possible membrane protein
No -57 -0.09 0.962221 CDS
No -108 -0.09 0.974691 CDS
D-serine/D-alanine/glycine transporter
No -75 -0.01 0.998534 Primary.TSS
Transcriptional regulator, IclR family
No -104 -0.14 0.962221 CDS
No -65 -0.1 0.962221 Primary.TSS
Malate synthase G (EC 2.3.3.9)
No -100 -0.07 0.962221 Primary.TSS
not assigned to any KEGG Pathway.
No TFOE experiment results were found

TRIP log2 fold abundance change

NA
Displaying 1 - 17 of 17
Condition Count Day Doublings Fitness U.I Plots
D0U 27 0 0.00 11.56 U
D3I 3 3 3.83 12.02 I
D3U 3 3 3.83 11.61 U
D5U 17 5 6.00 12.50 U
D5I 9 5 6.00 12.99 I
D7I 18 7 8.14 11.24 I
D7U 19 7 8.14 11.07 U
D14I 4 14 15.63 10.86 I
D14U 4 14 15.63 11.79 U
D17I 3 17 19.15 8.64 I
D17U 3 17 19.15 11.20 U
D21I 4 21 23.23 7.88 I
D21U 4 21 23.23 11.17 U
D24I 3 24 26.60 4.80 I
D24U 3 24 26.60 10.80 U
D28I 4 28 30.61 5.11 I
D28U 4 28 30.61 10.81 U