Rv3597c Histone protein Lsr2

Rv3597c (Histone protein Lsr2) is predicted to be co-regulated in modules bicluster_0140 with residual 0.62 and bicluster_0436 with residual 0.55.

This regulation is possibly mediated by two de-novo identified cis-regulatory motifs in each module with e-values , 0.00 and 0.00 for bicluster_0140 and 140.00 and 9,000.00 for bicluster_0436 respectively.

These modules are enriched for following go terms: .

This gene is found to be for growth on cholesterol.

Mutant available?:

Displaying 51 - 60 of 184
Gene Target Differential Expression Distance Expression pvalue Type
DNA-binding response regulator TrcR
No 65 -0.66 0.119946 Primary.TSS
PPE family protein
No 17 -0.06 0.913168 CDS
No -97 -0.07 0.933708 Primary.TSS
Induced -85 0.72 0.00957115 CDS
Transcriptional regulator, XRE family
No 45 -0.12 0.902792 CDS
2-methylcitrate dehydratase (EC 4.2.1.79)
No 24 0.78 0.337537 CDS
(MTV005.05c), len: 100. similar to the N-terminal region of the M. tuberculosis PE family of proteinseg. TR:O05297 (EMBL:Z93777) MTCI364.07 (99 aa), fasta scores; opt: 209 z-score: 407.6 E(): 1.6e-15, 37.4% identityin 99 aa overlap. Also simlar to the N-terminus of M. tuberculosis TR:P77909 (EMBL:U76006) ESTERASE/LIPASE (EC 3.1.1.3) (TRIACYLGLYCEROL LIPASE) (437 aa), fasta scores; opt: 193z-score: 381.8 E(): 4.4e-14, 37.2% identity in 94 aa overlap. Contains a helix-turn-heix motiffrom aa 88-109(+2.76 SD)
No 14 -0.37 0.732372 Primary.TSS
N-acetyl-1-D-myo-inosityl-2-amino-2-deoxy-alpha-D-glucopyranoside deacetylase MshB
No -71 0.07 0.889931 CDS
Polyketide synthase
No 6 -0.07 0.870465 Primary.TSS
No -1 -0.18 0.612402 Primary.TSS
not assigned to any KEGG Pathway.
GO:0003677

DNA binding

DNA binding

Details: 
Any molecular function by which a gene product interacts selectively with DNA (deoxyribonucleic acid).
GO Category: 
molecular_function
37
Total items in this category:  
GO:0005618

cell wall

cell wall

Details: 
The rigid or semi-rigid envelope lying outside the cell membrane of plant, fungal, and most prokaryotic cells, maintaining their shape and protecting them from osmotic lysis. In plants it is made of cellulose and, often, lignin; in fungi it is composed largely of polysaccharides; in bacteria it is composed of peptidoglycan.
GO Category: 
cellular_component
320
Total items in this category:  
GO:0005829

cytosol

cytosol

Details: 
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
GO Category: 
cellular_component
371
Total items in this category:  
GO:0005886

plasma membrane

plasma membrane

Details: 
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
GO Category: 
cellular_component
1284
Total items in this category:  
GO:0006355

regulation of transcription, DNA-dependent

regulation of transcription, DNA-dependent

Details: 
Any process that modulates the frequency, rate or extent of cellular DNA-dependent transcription.
GO Category: 
biological_process
15
Total items in this category:  
GO:0010039

response to iron ion

response to iron ion

Details: 
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an iron ion stimulus.
GO Category: 
biological_process
8
Total items in this category:  
GO:0040007

growth

growth

Details: 
The increase in size or mass of an entire organism, a part of an organism or a cell.
GO Category: 
biological_process
621
Total items in this category:  
GO:0051260

protein homooligomerization

protein homooligomerization

Details: 
The process of creating protein oligomers, compounds composed of a small number, usually between three and ten, of identical component monomers. Oligomers may be formed by the polymerization of a number of monomers or the depolymerization of a large protein polymer.
GO Category: 
biological_process
31
Total items in this category:  
No TFOE experiment results were found

TRIP log2 fold abundance change

NA
Displaying 1 - 17 of 17
Condition Count Day Doublings Fitness U.I Plots
D0U 27 0 0.00 12.23 U
D3I 3 3 3.83 12.54 I
D3U 3 3 3.83 11.81 U
D5I 9 5 6.00 14.38 I
D5U 17 5 6.00 14.34 U
D7I 18 7 8.14 12.54 I
D7U 19 7 8.14 13.00 U
D14I 4 14 15.63 13.04 I
D14U 4 14 15.63 13.70 U
D17U 3 17 19.15 13.67 U
D17I 3 17 19.15 12.58 I
D21I 4 21 23.23 12.68 I
D21U 4 21 23.23 13.83 U
D24I 3 24 26.60 12.35 I
D24U 3 24 26.60 13.82 U
D28I 4 28 30.61 12.08 I
D28U 4 28 30.61 14.28 U