Rv3765c putative two-component system response regulator

Rv3765c (putative two-component system response regulator) is predicted to be co-regulated in modules bicluster_0352 with residual 0.50 and bicluster_0526 with residual 0.56.

This regulation is possibly mediated by two de-novo identified cis-regulatory motifs in each module with e-values , 0.01 and 2,900.00 for bicluster_0352 and 450.00 and 8,100.00 for bicluster_0526 respectively.

These modules are enriched for following go terms: cellular biosynthetic process, organic substance biosynthetic process, translational elongation, macromolecule metabolic process, biosynthetic process, intracellular, macromolecular complex, translation elongation factor activity RNA binding.

This gene is found to be for growth on cholesterol.

Mutant available?:

Displaying 31 - 40 of 49
Gene Target Differential Expression Distance Expression pvalue Type
No 27 -0.96 0.0739115 Primary.TSS
PPE family protein
No -4 -0.62 0.0610229 CDS
Transcriptional regulator, AsnC family
No 1 -0.71 0.0770693 CDS
Transcriptional regulator, AsnC family
No 43 -0.71 0.0770693 Internal.TSS
Alanine dehydrogenase (EC 1.4.1.1)
No -44 -0.25 0.648991 Primary.TSS
(MTCY24G1.02), len: 496 aa, Probable polyketide synthase, almost identical to G560508 PKS002B (495 aa), fasta scores, opt: 3270, E(): 0, (99.6% identity in 496 aa overlap); contains PS00606 Beta-ketoacyl synthases active site; similar to MTCY338.20 (49.9% identity in 465 aa overlap) and MTCY24G1.09 (50.2% identity in 454 aa overlap) and MTCY22H8.03 (47.6% identity in 437 aa overlap)
No -18 0.12 0.807947 CDS
PPE family protein
Induced -29 1.05 0.0000000000231 Primary.TSS
Transcriptional regulator, TetR family
No 29 0.5 0.286227 Primary.TSS
WhiB-like transcription regulator
No -1 0.2 0.749769 Primary.TSS
Transcriptional regulator, TetR family
No 42 0.06 0.914454 Primary.TSS
not assigned to any KEGG Pathway.
GO:0008150

biological_process

biological_process

Details: 
Any process specifically pertinent to the functioning of integrated living units: cells, tissues, organs, and organisms. A process is a collection of molecular events with a defined beginning and end.
GO Category: 
biological_process
66
Total items in this category:  
GO:0008150

biological_process

biological_process

Details: 
Any process specifically pertinent to the functioning of integrated living units: cells, tissues, organs, and organisms. A process is a collection of molecular events with a defined beginning and end.
GO Category: 
biological_process
66
Total items in this category:  
GO:0010106

cellular response to iron ion starvation

cellular response to iron ion starvation

Details: 
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of iron ions.
GO Category: 
biological_process
14
Total items in this category:  
No TFOE experiment results were found

TRIP log2 fold abundance change

NA
Displaying 1 - 17 of 17
Condition Count Day Doublings Fitness U.I Plots
D0U 27 0 0.00 13.83 U
D3I 3 3 3.83 13.94 I
D3U 3 3 3.83 13.91 U
D5I 9 5 6.00 9.27 I
D5U 17 5 6.00 12.09 U
D7I 18 7 8.14 9.96 I
D7U 19 7 8.14 13.67 U
D14I 4 14 15.63 4.75 I
D14U 4 14 15.63 11.47 U
D17I 3 17 19.15 3.15 I
D17U 3 17 19.15 10.90 U
D21I 4 21 23.23 3.00 I
D21U 4 21 23.23 9.45 U
D24I 3 24 26.60 I
D24U 3 24 26.60 9.26 U
D28I 4 28 30.61 1.73 I
D28U 4 28 30.61 7.66 U