P9WKF5 adk, Rv0733, MTV041.07
Source: Uniprot proteome:up000001584
| Title | id | ORF names | Protein names | PubMed ID | Short | Synonyms | EnsemblBacteria |
|---|---|---|---|---|---|---|---|
| P9WKF5 KAD_MYCTU | MTV041.07 | Adenylate kinase (AK) (EC 2.7.4.3) (ATP-AMP transphosphorylase) (ATP:AMP phosphotransferase) (Adenylate monophosphate kinase) | 9634230, 10398370, 20066036, 14705932, 16672241 | adk | adk, Rv0733, MTV041.07 |
| Binding Site | Subcellular location |
|---|---|
| 31 31 AMP., 36 36 AMP., 92 92 AMP., 127 127 ATP., 129 129 AMP., 140 140 AMP., 166 166 ATP, via carbonyl oxygen. | Cytoplasm. |
| Domain | InterPro | Pfam | ProDom | Region | Similarity | SUPFAM |
|---|---|---|---|---|---|---|
| Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis. The LID domain is a solvent-exposed domain that is much shorter in Mycobacterium than in many other bacteria like E.coli. | Belongs to the adenylate kinase family. | SSF52540 |
| SSGCID ID |
|---|
| PDB | Protein Model Portal |
|---|---|
| EC number | KEGG KO | UniPathway |
|---|---|---|
| 2.7.4.3 | Purine metabolism, AMP biosynthesis via salvage pathway, AMP from ADP: step 1/1. |
| HOGENOM | KEGG KO | OMA | OrthoDB |
|---|---|---|---|