Module Functions 1 "Energy production and conversion:Mg-dependent DNase:Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase:Thymidylate kinase:Anthranilate/para-aminobenzoate synthases component I:Acyl carrier protein:Protein-tyrosine-phosphatase:Fatty acid/phospholipid biosynthesis enzyme:Nucleotide-binding protein implicated in inhibition of septum formation:ATPase involved in DNA replication:UDP-N-acetylmuramate dehydrogenase:Predicted periplasmic solute-binding protein:Tetraacyldisaccharide-1-P 4'-kinase:Cytochrome c, mono- and diheme variants:Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS/CutS homologs:Methylase of polypeptide chain release factors:Tfp pilus assembly protein PilZ:Transcriptional regulator of aromatic amino acids metabolism:Cell cycle control, cell division, chromosome partitioning:Amino acid transport and metabolism:Nucleotide transport and metabolism:Coenzyme transport and metabolism:Lipid transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:Replication, recombination and repair:Cell wall/membrane/envelope biogenesis:Cell motility:Purine metabolism:Pyrimidine metabolism:Amino sugar and nucleotide sugar metabolism:Lipopolysaccharide biosynthesis:Peptidoglycan biosynthesis:Glycerolipid metabolism:Glycerophospholipid metabolism:Folate biosynthesis:Metabolic pathways:DNA replication:Mismatch repair:Homologous recombination:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:Signal transduction mechanisms:TIGR00010:DTMP_kinase:maf:murB:plsX:TIGR00247:acyl_carrier:hemK_fam:pabB:holB:lpxK:pabC_Proteo:Intracellular trafficking, secretion, and vesicular transport:Poorly characterized:Cell division:Cellular processes:Protein modification and repair:Protein fate:DNA replication, recombination, and repair:DNA metabolism:Nucleotide and nucleoside interconversions:Purines, pyrimidines, nucleosides, and nucleotides:Biosynthesis:Fatty acid and phospholipid metabolism:Metabolism:Metabolism:Global:Replication and Repair:Genetic Information Processing:Metabolism of Cofactors and Vitamins:Glycan Biosynthesis and Metabolism:Nucleotide Metabolism:Lipid Metabolism:Hypothetical proteins:Carbohydrate Metabolism:Conserved:Unknown function:Enzymes of unknown specificity:Biosynthesis of cofactors, prosthetic groups, and carriers:Folic acid:Cell envelope:Biosynthesis and degradation of murein sacculus and peptidoglycan:Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides:Information storage and processing:Cellular processes and signaling:Metabolism" 2 "Energy production and conversion:Tryptophan synthase beta chain:Tryptophan synthase alpha chain:Glutathione peroxidase:Transcriptional regulator:Glycerophosphoryl diester phosphodiesterase:Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily):Predicted nucleoside-diphosphate-sugar epimerases:Predicted transcriptional regulators:ABC-type multidrug transport system, ATPase and permease components:Amidases related to nicotinamidase:Isopentenyldiphosphate isomerase:Acyl-CoA hydrolase:Predicted signal transduction protein:Cation transport ATPase:Uncharacterized protein conserved in bacteria:Amino acid transport and metabolism:Carbohydrate transport and metabolism:Lipid transport and metabolism:Transcription:Cell wall/membrane/envelope biogenesis:Posttranslational modification, protein turnover, chaperones:Inorganic ion transport and metabolism:Glycine serine and threonine metabolism:Phenylalanine tyrosine and tryptophan biosynthesis:Glutathione metabolism:Glycerophospholipid metabolism:Arachidonic acid metabolism:Metabolic pathways:Biosynthesis of secondary metabolites:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:Function unknown:Signal transduction mechanisms:trpA:trpB:ATPase-IB_hvy:CueR:Defense mechanisms:Metabolism:Metabolism:Global:Metabolism of Other Amino Acids:Amino Acid Metabolism:Lipid Metabolism:Poorly characterized:Metabolism:Cellular processes and signaling:Information storage and processing:Aromatic amino acid family:Amino acid biosynthesis:DNA interactions:Regulatory functions" 3 "Energy production and conversion:NhaP-type Na+/H+ and K+/H+ antiporters:Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II:Thiamine monophosphate synthase:Predicted amidohydrolase:Glycosyltransferase:Zn-dependent hydrolases, including glyoxylases:Putative GTPases (G3E family):Helicase subunit of the DNA excision repair complex:Glutathione S-transferase:2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases:Putative heme iron utilization protein:Alanine racemase:Chemotaxis signal transduction protein:Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis/translation initiation factor 2B, gamma/epsilon subunits (eIF-2Bgamma/eIF-2Bepsilon):Glutamine synthetase adenylyltransferase:Uncharacterized proteins, homologs of microcin C7 resistance protein MccF:Acyl-CoA dehydrogenases:Xanthine and CO dehydrogenases maturation factor, XdhC/CoxF family:Predicted flavoprotein involved in K+ transport:AraC-type DNA-binding domain-containing proteins:Uncharacterized homolog of the cytoplasmic domain of flagellar protein FhlB:Lysophospholipase L1 and related esterases:Arabinose efflux permease:Uncharacterized conserved protein:Uncharacterized protein conserved in bacteria:K+ transporter:Predicted membrane protein:Predicted membrane protein:Uncharacterized conserved protein:Uncharacterized protein conserved in archaea:Uncharacterized protein conserved in bacteria:Amino acid transport and metabolism:Carbohydrate transport and metabolism:Coenzyme transport and metabolism:Lipid transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:Replication, recombination and repair:Cell wall/membrane/envelope biogenesis:Cell motility:Posttranslational modification, protein turnover, chaperones:Inorganic ion transport and metabolism:Fatty acid metabolism:D-Alanine metabolism:Glutathione metabolism:Metabolic pathways:Two-component system:Nucleotide excision repair:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:Function unknown:Signal transduction mechanisms:alr:mutt:uvrb:efflux_EmrB:Ubi-OHases:TIGR02099:Defense mechanisms:Biosynthesis of cofactors, prosthetic groups, and carriers:Conserved:Hypothetical proteins:Other:Transport and binding proteins:DNA replication, recombination, and repair:DNA metabolism:Metabolism:Global:Signal Transduction:Environmental Information Processing:Replication and Repair:Genetic Information Processing:Metabolism of Other Amino Acids:Metabolism:Lipid Metabolism:Poorly characterized:Metabolism:Cellular processes and signaling:Information storage and processing:Biosynthesis and degradation of murein sacculus and peptidoglycan:Cell envelope:Menaquinone and ubiquinone" 4 "Energy production and conversion:Dihydrofolate reductase:NTP pyrophosphohydrolases including oxidative damage repair enzymes:Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases:Mg2+ and Co2+ transporters:Small-conductance mechanosensitive channel:ABC-type dipeptide transport system, periplasmic component:ABC-type amino acid transport/signal transduction systems, periplasmic component/domain:DNA polymerase III, epsilon subunit and related 3'-5' exonucleases:Hemolysins and related proteins containing CBS domains:Transcriptional regulators:Tryptophan 2,3-dioxygenase (vermilion):ABC-type spermidine/putrescine transport systems, ATPase components:Delta 1-pyrroline-5-carboxylate dehydrogenase:Uncharacterized protein conserved in bacteria:Amino acid transport and metabolism:Nucleotide transport and metabolism:Carbohydrate transport and metabolism:Coenzyme transport and metabolism:Transcription:Replication, recombination and repair:Cell wall/membrane/envelope biogenesis:Inorganic ion transport and metabolism:Purine metabolism:Pyrimidine metabolism:Alanine aspartate and glutamate metabolism:Arginine and proline metabolism:Tryptophan metabolism:Metabolic pathways:Biosynthesis of secondary metabolites:ABC transporters:DNA replication:Mismatch repair:Homologous recombination:General function prediction only:Function unknown:Signal transduction mechanisms:dnaq:D1pyr5carbox3:trp_2_3_diox:Metabolism:Cellular processes and signaling:Information storage and processing:Degradation of DNA:DNA metabolism:Amino acids and amines:Energy metabolism:Metabolism:Metabolism:Global:Membrane Transport:Environmental Information Processing:Replication and Repair:Genetic Information Processing:Amino Acid Metabolism:Poorly characterized:Nucleotide Metabolism" 5 "Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis:Spermidine synthase:Nucleoside-diphosphate-sugar epimerases:Glycosyltransferases involved in cell wall biogenesis:Signal transduction histidine kinase:Predicted xylanase/chitin deacetylase:Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain:Predicted UDP-glucose 6-dehydrogenase:S-adenosylmethionine decarboxylase:4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family:Amino acid transport and metabolism:Carbohydrate transport and metabolism:Transcription:Cell wall/membrane/envelope biogenesis:Pentose and glucuronate interconversions:Ascorbate and aldarate metabolism:Cysteine and methionine metabolism:Arginine and proline metabolism:beta-Alanine metabolism:Glutathione metabolism:Starch and sucrose metabolism:Amino sugar and nucleotide sugar metabolism:Metabolic pathways:Biosynthesis of secondary metabolites:Two-component system:Signal transduction mechanisms:NDP-sugDHase:SAM_DCase_Bsu:Global:Signal Transduction:Environmental Information Processing:Metabolism of Other Amino Acids:Amino Acid Metabolism:Metabolism:Polyamine biosynthesis:Carbohydrate Metabolism:Information storage and processing:Cellular processes and signaling:Metabolism:Central intermediary metabolism:Metabolism" 6 "3-polyprenyl-4-hydroxybenzoate decarboxylase:Stress-induced morphogen (activity unknown):Glutaredoxin-related protein:Single-stranded DNA-binding protein:Small-conductance mechanosensitive channel:UDP-N-acetylmuramate-alanine ligase:Bacterial nucleoid DNA-binding protein:FKBP-type peptidyl-prolyl cis-trans isomerases 2:UDP-glucose pyrophosphorylase:Uncharacterized protein conserved in bacteria:Beta-propeller domains of methanol dehydrogenase type:Protein-disulfide isomerase:Uncharacterized protein conserved in bacteria:Uncharacterized conserved protein:Cell division protein:Uncharacterized protein conserved in bacteria:Serine protease inhibitor ecotin:Predicted integral membrane protein:Cell cycle control, cell division, chromosome partitioning:Coenzyme transport and metabolism:Replication, recombination and repair:Cell wall/membrane/envelope biogenesis:Posttranslational modification, protein turnover, chaperones:Pentose and glucuronate interconversions:Galactose metabolism:Ubiquinone and other terpenoid-quinone biosynthesis:Starch and sucrose metabolism:Amino sugar and nucleotide sugar metabolism:Metabolic pathways:Biosynthesis of secondary metabolites:DNA replication:Mismatch repair:Homologous recombination:General function prediction only:Function unknown:Signal transduction mechanisms:TIGR00365:ubiX_pad:ssb:mpl:galU:septum_zipA:CbtA:Cell envelope:Carbohydrate Metabolism:Metabolism of Cofactors and Vitamins:Genetic Information Processing:Replication and Repair:Global:Metabolism:Energy metabolism:Electron transport:DNA metabolism:DNA replication, recombination, and repair:Cellular processes:Cell division:Unknown function:Enzymes of unknown specificity:Metabolism:Biosynthesis and degradation of murein sacculus and peptidoglycan:Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides:Information storage and processing:Cellular processes and signaling:Metabolism:Poorly characterized" 7 "Energy production and conversion:dGTP triphosphohydrolase:Malic enzyme:Molybdopterin biosynthesis enzymes:Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily):NADPH:quinone reductase and related Zn-dependent oxidoreductases:Enoyl-[acyl-carrier-protein] reductase (NADH):Predicted oxidoreductases (related to aryl-alcohol dehydrogenases):Urea amidohydrolase (urease) alpha subunit:Urea amidohydrolase (urease) beta subunit:ABC-type multidrug transport system, permease component:Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases):Hydrolases of the alpha/beta superfamily:ABC-type multidrug transport system, ATPase component:ABC-type transport system involved in resistance to organic solvents, periplasmic component:Uncharacterized conserved protein:Dioxygenases related to 2-nitropropane dioxygenase:Uncharacterized conserved protein:TRAP-type uncharacterized transport system, periplasmic component:Surface lipoprotein:Predicted aminoglycoside phosphotransferase:Uncharacterized protein conserved in bacteria:Uncharacterized protein conserved in bacteria:Uncharacterized protein conserved in bacteria:ABC-type oligopeptide transport system, periplasmic component:Amino acid transport and metabolism:Nucleotide transport and metabolism:Coenzyme transport and metabolism:Lipid transport and metabolism:Cell wall/membrane/envelope biogenesis:Fatty acid biosynthesis:Purine metabolism:Arginine and proline metabolism:Pyruvate metabolism:Atrazine degradation:Metabolic pathways:Microbial metabolism in diverse environments:ABC transporters:Two-component system:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:Function unknown:molyb_syn:urease_beta:TIGR00266:dGTP_triPase:urease_alph:QEGLA:poly_P_AMP_trns:Defense mechanisms:Metabolism:Carbohydrate Metabolism:Lipid Metabolism:Nucleotide Metabolism:Amino Acid Metabolism:Xenobiotics Biodegradation and Metabolism:Environmental Information Processing:Membrane Transport:Signal Transduction:Global:Metabolism:Central intermediary metabolism:Phosphorus compounds:Nitrogen metabolism:Purines, pyrimidines, nucleosides, and nucleotides:Nucleotide and nucleoside interconversions:Hypothetical proteins:Conserved:Cellular processes and signaling:Metabolism:Poorly characterized" 8 "Energy production and conversion:Lipoate-protein ligase A:Indole-3-glycerol phosphate synthase:Phosphoribosyl-AMP cyclohydrolase:Phosphoribosyl-ATP pyrophosphohydrolase:Anthranilate/para-aminobenzoate synthases component I:Anthranilate/para-aminobenzoate synthases component II:Anthranilate phosphoribosyltransferase:ATPase involved in DNA replication initiation:Glycine/D-amino acid oxidases (deaminating):3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase:Nitroreductase:ABC-type amino acid transport/signal transduction systems, periplasmic component/domain:Predicted glycosyltransferases:Flagellar motor component:Flagellar motor protein:Conserved protein/domain typically associated with flavoprotein oxygenases, DIM6/NTAB family:ADP-heptose synthase, bifunctional sugar kinase/adenylyltransferase:Cytochrome B561:Uncharacterized protein conserved in bacteria:Serine protease inhibitor ecotin:Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain:Amino acid transport and metabolism:Coenzyme transport and metabolism:Replication, recombination and repair:Cell wall/membrane/envelope biogenesis:Cell motility:Histidine metabolism:Phenylalanine tyrosine and tryptophan biosynthesis:Lipopolysaccharide biosynthesis:Thiamine metabolism:Metabolic pathways:Biosynthesis of secondary metabolites:Two-component system:Bacterial chemotaxis:Flagellar assembly:General function prediction only:Function unknown:Signal transduction mechanisms:aroFGH:cyt_tran_rel:GGDEF:DnaA:trpE_most:trpG_papA:trpD:thiamin_ThiO:histidine_hisI:MotA1:Metabolism:Cellular processes and signaling:Information storage and processing:Other:Signal transduction:Thiamine:Biosynthesis of cofactors, prosthetic groups, and carriers:Histidine family:Aromatic amino acid family:Amino acid biosynthesis:DNA replication, recombination, and repair:DNA metabolism:Metabolism:Metabolism:Global:Cell Motility:Cellular Processes:Signal Transduction:Environmental Information Processing:Metabolism of Cofactors and Vitamins:Glycan Biosynthesis and Metabolism:Poorly characterized:Amino Acid Metabolism" 9 "Energy production and conversion:Dihydrofolate reductase:NTP pyrophosphohydrolases including oxidative damage repair enzymes:Phosphatidylglycerophosphate synthase:Transcriptional regulator:Glutathione S-transferase:3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase:ABC-type molybdate transport system, periplasmic component:Molybdopterin-guanine dinucleotide biosynthesis protein A:NAD/NADP transhydrogenase beta subunit:Transcriptional regulators:Flagellar basal body-associated protein:TRAP-type C4-dicarboxylate transport system, periplasmic component:AraC-type DNA-binding domain-containing proteins:Uncharacterized conserved protein:DNA-binding HTH domain-containing proteins:Transposase and inactivated derivatives:Cytochrome B561:Uncharacterized conserved protein:NAD/NADP transhydrogenase alpha subunit:P pilus assembly protein, pilin FimA:Amino acid transport and metabolism:Carbohydrate transport and metabolism:Coenzyme transport and metabolism:Lipid transport and metabolism:Transcription:Replication, recombination and repair:Cell motility:Posttranslational modification, protein turnover, chaperones:Inorganic ion transport and metabolism:Arginine and proline metabolism:Phenylalanine tyrosine and tryptophan biosynthesis:Glutathione metabolism:Glycerophospholipid metabolism:Nicotinate and nicotinamide metabolism:Metabolic pathways:Biosynthesis of secondary metabolites:ABC transporters:General function prediction only:Function unknown:aroFGH:modA:adhes_NPXG:molyb_mobA:Intracellular trafficking, secretion, and vesicular transport:Information storage and processing:Lipid Metabolism:Cellular processes and signaling:Metabolism:Poorly characterized:Molybdopterin:Metabolism:Biosynthesis of cofactors, prosthetic groups, and carriers:Aromatic amino acid family:Amino acid biosynthesis:Anions:Transport and binding proteins:Metabolism:Global:Membrane Transport:Environmental Information Processing:Metabolism of Cofactors and Vitamins:Metabolism of Other Amino Acids:Amino Acid Metabolism" 10 "Energy production and conversion:Molecular chaperone (small heat shock protein):Predicted Zn-dependent proteases and their inactivated homologs:ATPases with chaperone activity, ATP-binding subunit:Transcriptional regulator:Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily):Glutathione S-transferase:Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases):ABC-type multidrug transport system, ATPase and permease components:Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes:Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily:Ketopantoate reductase:Uncharacterized conserved protein:Uncharacterized Fe-S protein:Coenzyme transport and metabolism:Lipid transport and metabolism:Transcription:Cell wall/membrane/envelope biogenesis:Posttranslational modification, protein turnover, chaperones:Glutathione metabolism:Pantothenate and CoA biosynthesis:Porphyrin and chlorophyll metabolism:Metabolic pathways:Biosynthesis of secondary metabolites:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:Function unknown:PduO_Nterm:apbA_panE:ClpA:Defense mechanisms:Metabolism of Other Amino Acids:Information storage and processing:Cellular processes and signaling:Metabolism:Poorly characterized:Metabolism:Heme, porphyrin, and cobalamin:Biosynthesis of cofactors, prosthetic groups, and carriers:Degradation of proteins, peptides, and glycopeptides:Protein fate:Metabolism:Global:Metabolism of Cofactors and Vitamins:Pantothenate and coenzyme A" 11 "DnaK suppressor protein:DNA repair proteins:Predicted transcriptional regulator:Phage tail sheath protein FI:Phage tail tube protein FII:Phage protein U:Phage protein D:Phage baseplate assembly protein W:Uncharacterized protein conserved in bacteria:Mu-like prophage protein:Phage-related baseplate assembly protein:Bacteriophage P2-related tail formation protein:Phage P2 baseplate assembly protein gpV:Phage-related protein, tail component:P2-like prophage tail protein X:Phage-related tail fibre protein:Predicted membrane protein:Transcription:Replication, recombination and repair:General function prediction only:Function unknown:Signal transduction mechanisms:radc:tail_tube:tail_P2_I:phage_P2_V:TIGR02270:C4_traR_proteo:Prophage functions:Mobile and extrachromosomal element functions:DNA replication, recombination, and repair:DNA metabolism:Cellular processes and signaling:Poorly characterized:Information storage and processing:Conserved:Hypothetical proteins" 12 "Na+-driven multidrug efflux pump:Predicted permeases:Multidrug resistance efflux pump:Outer membrane receptor proteins, mostly Fe transport:Uncharacterized protein, possibly involved in aromatic compounds catabolism:Predicted membrane-associated, metal-dependent hydrolase:Nitrate/nitrite transporter:Xanthine/uracil permeases:Choline dehydrogenase and related flavoproteins:Arabinose efflux permease:P pilus assembly protein, porin PapC:Predicted double-glycine peptidase:Predicted flavin-nucleotide-binding protein structurally related to pyridoxine 5'-phosphate oxidase:ABC-type uncharacterized transport system, duplicated ATPase component:ABC-type uncharacterized transport system, permease component:Amino acid transport and metabolism:Nucleotide transport and metabolism:Carbohydrate transport and metabolism:Cell motility:Inorganic ion transport and metabolism:ABC transporters:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:matE:ncs2:2A0108:Intracellular trafficking, secretion, and vesicular transport:Defense mechanisms:Membrane Transport:Environmental Information Processing:Poorly characterized:Metabolism:Cellular processes and signaling:Other:Nucleosides, purines and pyrimidines:Anions:Transport and binding proteins" 13 "Ribosomal protein S7:Ribosomal protein L11:Ribosomal protein L1:Ribosomal protein L3:Folylpolyglutamate synthase:Translation elongation factors (GTPases):RNase P protein component:Holliday junction resolvasome, DNA-binding subunit:Predicted thioesterase:Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases):Outer membrane protein and related peptidoglycan-associated (lipo)proteins:Uncharacterized protein conserved in bacteria:Coenzyme transport and metabolism:Lipid transport and metabolism:Translation, ribosomal structure and biogenesis:Replication, recombination and repair:Cell wall/membrane/envelope biogenesis:Fatty acid biosynthesis:Ubiquinone and other terpenoid-quinone biosynthesis:Benzoate degradation:Folate biosynthesis:Biosynthesis of unsaturated fatty acids:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:Ribosome:Homologous recombination:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:Function unknown:TIGR00051:ruvA:rnpA:small_GTP:rpsG_bact:rplA_bact:folC:L11_bact:3oxo_ACP_reduc:Pal_lipo:L3_bact:Metabolism:Global:Replication and Repair:Translation:Genetic Information Processing:Xenobiotics Biodegradation and Metabolism:Metabolism of Cofactors and Vitamins:Lipid Metabolism:Fatty acid and phospholipid metabolism:Biosynthesis:DNA metabolism:DNA replication, recombination, and repair:Transcription:RNA processing:Protein synthesis:Ribosomal proteins: synthesis and modification:Unknown function:General:Biosynthesis of cofactors, prosthetic groups, and carriers:Folic acid:Information storage and processing:Cellular processes and signaling:Metabolism:Poorly characterized:Metabolism" 14 "Energy production and conversion:Alanyl-tRNA synthetase:Acetyltransferase (isoleucine patch superfamily):NAD-dependent DNA ligase (contains BRCT domain type II):Protein-tyrosine-phosphatase:Nucleotide-binding protein implicated in inhibition of septum formation:2-polyprenylphenol hydroxylase and related flavodoxin oxidoreductases:Asp-tRNAAsn/Glu-tRNAGln amidotransferase C subunit:Methionine synthase I, cobalamin-binding domain:Tetraacyldisaccharide-1-P 4'-kinase:16S RNA G1207 methylase RsmC:Septum formation initiator:Uncharacterized protein conserved in bacteria:Predicted NTP binding protein (contains STAS domain):Uncharacterized protein conserved in bacteria:Uncharacterized protein conserved in bacteria:Cell cycle control, cell division, chromosome partitioning:Amino acid transport and metabolism:Coenzyme transport and metabolism:Translation, ribosomal structure and biogenesis:Replication, recombination and repair:Cell wall/membrane/envelope biogenesis:Cysteine and methionine metabolism:Amino sugar and nucleotide sugar metabolism:Lipopolysaccharide biosynthesis:One carbon pool by folate:Aminoacyl-tRNA biosynthesis:Metabolic pathways:Biosynthesis of secondary metabolites:DNA replication:Base excision repair:Nucleotide excision repair:Mismatch repair:General function prediction only:Function unknown:Signal transduction mechanisms:gatC:maf:alaS:rlpA:dnlj:lpxK:metH:iscX_yfhJ:Metabolism:Poorly characterized:tRNA aminoacylation:Protein synthesis:DNA replication, recombination, and repair:DNA metabolism:Metabolism:Global:Metabolism:Replication and Repair:Translation:Genetic Information Processing:Metabolism of Cofactors and Vitamins:Glycan Biosynthesis and Metabolism:Amino Acid Metabolism:Cellular processes:Carbohydrate Metabolism:Cell division:Amino acid biosynthesis:Aspartate family:Biosynthesis of cofactors, prosthetic groups, and carriers:Other:Cell envelope:Other:Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides:Information storage and processing:Cellular processes and signaling" 15 "Energy production and conversion:Cell division GTPase:L-asparaginase/archaeal Glu-tRNAGln amidotransferase subunit D:Isocitrate dehydrogenases:ABC-type branched-chain amino acid transport systems, periplasmic component:Spermidine/putrescine-binding periplasmic protein:ABC-type amino acid transport/signal transduction systems, periplasmic component/domain:ABC-type polar amino acid transport system, ATPase component:Ribosome-associated protein Y (PSrp-1):NAD-specific glutamate dehydrogenase:Succinylglutamate desuccinylase:Azurin:Cell cycle control, cell division, chromosome partitioning:Amino acid transport and metabolism:Translation, ribosomal structure and biogenesis:Citrate cycle (TCA cycle):Alanine aspartate and glutamate metabolism:Arginine and proline metabolism:D-Glutamine and D-glutamate metabolism:Glutathione metabolism:Carbon fixation pathways in prokaryotes:Nitrogen metabolism:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:ABC transporters:Signal transduction mechanisms:ftsZ:prok_nadp_idh:asnASE_II:yfiA:azurin:arg_catab_astE:Cellular processes:Carbohydrate Metabolism:Energy Metabolism:Amino Acid Metabolism:Metabolism of Other Amino Acids:Environmental Information Processing:Membrane Transport:Global:Metabolism:Energy metabolism:Amino acids and amines:Electron transport:TCA cycle:Protein synthesis:Translation factors:Metabolism:Cell division:Information storage and processing:Cellular processes and signaling:Metabolism" 16 "Transcriptional regulator:Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily):Predicted ATPase with chaperone activity:Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases:Glycine/D-amino acid oxidases (deaminating):Predicted Rossmann fold nucleotide-binding protein involved in DNA uptake:Multidrug resistance efflux pump:TRAP-type C4-dicarboxylate transport system, large permease component:TRAP-type C4-dicarboxylate transport system, periplasmic component:Pyridoxal phosphate biosynthesis protein:Sugar phosphate permease:Arabinose efflux permease:TRAP-type C4-dicarboxylate transport system, small permease component:Uncharacterized protein conserved in bacteria:Uncharacterized protein conserved in bacteria:Predicted metal-dependent hydrolase of the TIM-barrel fold:Proline racemase:Amino acid transport and metabolism:Carbohydrate transport and metabolism:Coenzyme transport and metabolism:Transcription:Replication, recombination and repair:Posttranslational modification, protein turnover, chaperones:Arginine and proline metabolism:Vitamin B6 metabolism:Metabolic pathways:General function prediction only:Function unknown:TIGR00368:efflux_EmrB:dprA:dctM:hydantase:Phn_aa_oxid:Intracellular trafficking, secretion, and vesicular transport:Defense mechanisms:Metabolism of Cofactors and Vitamins:Cellular processes and signaling:Amino Acid Metabolism:Metabolism:Poorly characterized:Information storage and processing:Metabolism:General:Unknown function:DNA transformation:Cellular processes:Other:Carbohydrates, organic alcohols, and acids:Transport and binding proteins:Metabolism:Global" 17 "Energy production and conversion:Anthranilate/para-aminobenzoate synthases component I:3-oxoacyl-[acyl-carrier-protein] synthase III:Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases:Zn-dependent hydrolases, including glyoxylases:Anthranilate/para-aminobenzoate synthases component II:Transcriptional regulator:2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases:N-acyl-L-homoserine lactone synthetase:Uncharacterized conserved protein:Amino acid transport and metabolism:Coenzyme transport and metabolism:Lipid transport and metabolism:Transcription:Fatty acid biosynthesis:Phenylalanine tyrosine and tryptophan biosynthesis:Metabolic pathways:Biosynthesis of secondary metabolites:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:Function unknown:Signal transduction mechanisms:trpE_proteo:trpG_papA:Cellular processes and signaling:Lipid Metabolism:Metabolism:Poorly characterized:Metabolism:Information storage and processing:Aromatic amino acid family:Amino acid biosynthesis:Metabolism:Global:Amino Acid Metabolism" 18 "Energy production and conversion:Putative translation factor (SUA5):Prephenate dehydratase:Methionyl-tRNA synthetase:Predicted acid phosphatase:Predicted metal-dependent phosphoesterases (PHP family):Periplasmic serine proteases (ClpP class):2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases:Fe2+/Zn2+ uptake regulation proteins:ABC-type Mn2+/Zn2+ transport systems, permease components:ABC-type Mn/Zn transport systems, ATPase component:Transcription-repair coupling factor (superfamily II helicase):DNA polymerase III, delta subunit:Cell division protein:Uncharacterized protein conserved in bacteria:Predicted ATPase involved in cell division:Intracellular septation protein A:ABC-type Zn2+ transport system, periplasmic component/surface adhesin:Cell cycle control, cell division, chromosome partitioning:Amino acid transport and metabolism:Coenzyme transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:Replication, recombination and repair:Posttranslational modification, protein turnover, chaperones:Inorganic ion transport and metabolism:Ubiquinone and other terpenoid-quinone biosynthesis:Purine metabolism:Pyrimidine metabolism:Phenylalanine tyrosine and tryptophan biosynthesis:Selenocompound metabolism:Nicotinate and nicotinamide metabolism:Aminoacyl-tRNA biosynthesis:Metabolic pathways:Biosynthesis of secondary metabolites:ABC transporters:DNA replication:Nucleotide excision repair:Mismatch repair:Homologous recombination:General function prediction only:Function unknown:TIGR00057:surE:metG:mfd:apaH:SppA_dom:ispZ:holA:CM_P2:UbiH:FtsE:Intracellular trafficking, secretion, and vesicular transport:Information storage and processing:Nucleotide Metabolism:Amino Acid Metabolism:Metabolism of Other Amino Acids:Metabolism of Cofactors and Vitamins:Genetic Information Processing:Translation:Replication and Repair:Environmental Information Processing:Membrane Transport:Global:Metabolism:DNA metabolism:DNA replication, recombination, and repair:Protein synthesis:tRNA aminoacylation:Protein fate:Degradation of proteins, peptides, and glycopeptides:Cellular processes:Cell division:Adaptations to atypical conditions:Unknown function:General:Amino acid biosynthesis:Aromatic amino acid family:Biosynthesis of cofactors, prosthetic groups, and carriers:Menaquinone and ubiquinone:Metabolism:Cellular processes and signaling:Metabolism:Poorly characterized" 19 "Energy production and conversion:Ribosomal protein S12:GTPases - translation elongation factors:Ribosomal protein S13:S-adenosylmethionine synthetase:Ribosomal protein L36:S-adenosylhomocysteine hydrolase:5,10-methylenetetrahydrofolate reductase:Succinate dehydrogenase/fumarate reductase, cytochrome b subunit:Succinate dehydrogenase, hydrophobic anchor subunit:Methylase involved in ubiquinone/menaquinone biosynthesis:Cbb3-type cytochrome oxidase, subunit 1:Amino acid transport and metabolism:Coenzyme transport and metabolism:Translation, ribosomal structure and biogenesis:Posttranslational modification, protein turnover, chaperones:Citrate cycle (TCA cycle):Oxidative phosphorylation:Cysteine and methionine metabolism:Selenocompound metabolism:Toluene degradation:Butanoate metabolism:One carbon pool by folate:Methane metabolism:Carbon fixation pathways in prokaryotes:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:Ribosome:small_GTP:fadh2:ccoN:ahcY:rpsL_bact:rpmJ_bact:metK:succ_dehyd_anc:succ_dehyd_cytB:bact_S13:TCA cycle:Protein synthesis:Ribosomal proteins: synthesis and modification:Unknown function:General:Amino acid biosynthesis:Aspartate family:Information storage and processing:Cellular processes and signaling:Metabolism:Amino acids and amines:Energy metabolism:Other:Central intermediary metabolism:Metabolism:Metabolism:Global:Translation:Genetic Information Processing:Xenobiotics Biodegradation and Metabolism:Metabolism of Cofactors and Vitamins:Metabolism of Other Amino Acids:Amino Acid Metabolism:Energy Metabolism:Electron transport:Carbohydrate Metabolism" 20 "NhaP-type Na+/H+ and K+/H+ antiporters:Predicted Co/Zn/Cd cation transporters:Superfamily II DNA/RNA helicases, SNF2 family:ABC-type antimicrobial peptide transport system, permease component:Transcriptional regulator:Signal transduction histidine kinase:Predicted dehydrogenases and related proteins:Signal peptidase I:Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain:Cation/multidrug efflux pump:Membrane protein TerC, possibly involved in tellurium resistance:Enoyl-CoA hydratase/carnithine racemase:ABC-type spermidine/putrescine transport system, permease component I:Kef-type K+ transport systems, predicted NAD-binding component:Transcriptional regulator:Phosphatidylserine/phosphatidylglycerophosphate/cardiolipin synthases and related enzymes:Multidrug resistance efflux pump:Predicted acyltransferases:RNA:NAD 2'-phosphotransferase:Acyl-CoA dehydrogenases:Membrane transporters of cations and cationic drugs:ABC-type proline/glycine betaine transport systems, periplasmic components:FOG: GGDEF domain:AraC-type DNA-binding domain-containing proteins:2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase:DNA-binding HTH domain-containing proteins:Uncharacterized protein conserved in bacteria:Predicted membrane protein:P pilus assembly protein, pilin FimA:Uncharacterized protein conserved in bacteria:Predicted transmembrane sensor domain:Uncharacterized conserved protein:Uncharacterized protein conserved in bacteria:Amino acid transport and metabolism:Coenzyme transport and metabolism:Lipid transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:Replication, recombination and repair:Cell motility:Inorganic ion transport and metabolism:Fatty acid metabolism:Valine leucine and isoleucine degradation:Geraniol degradation:Lysine degradation:Benzoate degradation:Tryptophan metabolism:beta-Alanine metabolism:Naphthalene degradation:Aminobenzoate degradation:Propanoate metabolism:Butanoate metabolism:Limonene and pinene degradation:Caprolactam degradation:Aminoacyl-tRNA biosynthesis:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:ABC transporters:Protein export:General function prediction only:Function unknown:Signal transduction mechanisms:GGDEF:a_cpa1:2A0125:CDF:fkbM_fam:sigpep_I_bact:ABC_choline_bnd:R_switched_YjbE:Intracellular trafficking, secretion, and vesicular transport:Defense mechanisms:Cellular processes and signaling:Information storage and processing:Other:Signal transduction:Adaptations to atypical conditions:Cellular processes:Cations and iron carrying compounds:Amino acids, peptides and amines:Transport and binding proteins:Protein and peptide secretion and trafficking:Protein fate:Poorly characterized:Metabolism:Metabolism:Global:Membrane Transport:Environmental Information Processing:Folding Sorting and Degradation:Translation:Genetic Information Processing:Xenobiotics Biodegradation and Metabolism:Metabolism of Terpenoids and Polyketides:Metabolism of Other Amino Acids:Amino Acid Metabolism:Lipid Metabolism:Metabolism:Carbohydrate Metabolism" 21 "Nucleoside-diphosphate-sugar epimerases:Cation transport ATPase:Amino acid transporters:Universal stress protein UspA and related nucleotide-binding proteins:Zn-dependent alcohol dehydrogenases:Multidrug resistance efflux pump:DnaK suppressor protein:Predicted phosphatase homologous to the C-terminal domain of histone macroH2A1:Amino acid transport and metabolism:Carbohydrate transport and metabolism:Cell wall/membrane/envelope biogenesis:Inorganic ion transport and metabolism:Glycolysis / Gluconeogenesis:Fatty acid metabolism:Tyrosine metabolism:Lipopolysaccharide biosynthesis:Chloroalkane and chloroalkene degradation:Naphthalene degradation:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:General function prediction only:Signal transduction mechanisms:2A0302:ATPase_P-type:heptose_epim:Defense mechanisms:Poorly characterized:Carbohydrate Metabolism:Lipid Metabolism:Amino Acid Metabolism:Glycan Biosynthesis and Metabolism:Xenobiotics Biodegradation and Metabolism:Global:Metabolism:Transport and binding proteins:Amino acids, peptides and amines:Cell envelope:Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides:Cellular processes and signaling:Metabolism:Metabolism" 22 "Energy production and conversion:2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway):Transcriptional regulator:ABC-type nitrate/sulfonate/bicarbonate transport system, permease component:ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components:Succinate dehydrogenase/fumarate reductase, flavoprotein subunit:ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component:Ferredoxin:Predicted transcriptional regulators:FOG: HEAT repeat:Outer membrane receptor proteins, mostly Fe transport:Probable taurine catabolism dioxygenase:Gentisate 1,2-dioxygenase:Uncharacterized protein conserved in bacteria:Transcription:Inorganic ion transport and metabolism:Tyrosine metabolism:Taurine and hypotaurine metabolism:Metabolic pathways:Microbial metabolism in diverse environments:ABC transporters:Secondary metabolites biosynthesis, transport and catabolism:Function unknown:TonB-siderophor:gentisate_1_2:Poorly characterized:Amino Acid Metabolism:Metabolism of Other Amino Acids:Environmental Information Processing:Membrane Transport:Global:Metabolism:Transport and binding proteins:Porins:Information storage and processing:Metabolism:Metabolism" 23 "Energy production and conversion:Polyprenyltransferase (cytochrome oxidase assembly factor):1-acyl-sn-glycerol-3-phosphate acyltransferase:GMP synthase - Glutamine amidotransferase domain:ABC-type antimicrobial peptide transport system, permease component:ABC-type Fe3+-hydroxamate transport system, periplasmic component:NAD-dependent aldehyde dehydrogenases:ABC-type antimicrobial peptide transport system, ATPase component:Putative threonine efflux protein:Predicted membrane-bound metal-dependent hydrolases:Membrane transporters of cations and cationic drugs:FOG: GGDEF domain:Nitrate/nitrite transporter:Putative homoserine kinase type II (protein kinase fold):Sterol desaturase:Uncharacterized conserved protein:Uncharacterized protein conserved in bacteria:Predicted membrane protein:Predicted permease, DMT superfamily:Amino acid transport and metabolism:Nucleotide transport and metabolism:Lipid transport and metabolism:Posttranslational modification, protein turnover, chaperones:Inorganic ion transport and metabolism:Oxidative phosphorylation:Glycerolipid metabolism:Glycerophospholipid metabolism:Porphyrin and chlorophyll metabolism:Metabolic pathways:Biosynthesis of secondary metabolites:ABC transporters:General function prediction only:Function unknown:Signal transduction mechanisms:GGDEF:2A0106:cyoE_ctaB:Defense mechanisms:Metabolism:Poorly characterized:Metabolism:Cellular processes and signaling:Other:Signal transduction:Heme, porphyrin, and cobalamin:Biosynthesis of cofactors, prosthetic groups, and carriers:Unknown substrate:Transport and binding proteins:Metabolism:Global:Membrane Transport:Environmental Information Processing:Metabolism of Cofactors and Vitamins:Lipid Metabolism:Energy Metabolism" 24 "Energy production and conversion:Dihydrodipicolinate synthase/N-acetylneuraminate lyase:(acyl-carrier-protein) S-malonyltransferase:Acetyltransferases:Transcriptional regulator:Acetyl-CoA carboxylase beta subunit:ABC-type amino acid transport/signal transduction systems, periplasmic component/domain:Succinate dehydrogenase/fumarate reductase, flavoprotein subunit:ABC-type polar amino acid transport system, ATPase component:Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific:Uncharacterized conserved protein:Triphosphoribosyl-dephospho-CoA synthetase:Xanthine/uracil permeases:Cytochrome B561:Topoisomerase IB:Putative silver efflux pump:Uncharacterized conserved protein:Proline racemase:Ketosteroid isomerase homolog:Amino acid transport and metabolism:Nucleotide transport and metabolism:Carbohydrate transport and metabolism:Coenzyme transport and metabolism:Lipid transport and metabolism:Transcription:Replication, recombination and repair:Cell wall/membrane/envelope biogenesis:Inorganic ion transport and metabolism:Fatty acid biosynthesis:Lysine biosynthesis:Arginine and proline metabolism:Amino sugar and nucleotide sugar metabolism:Carbon fixation pathways in prokaryotes:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:ABC transporters:Phosphotransferase system (PTS):General function prediction only:Function unknown:Signal transduction mechanisms:ncs2:malonate_madM:EIIB_glc:2A0601:mdcA:malonate_delta:malonate_mdcH:malonate_mdcB:malonate_beta:malonate_gamma:malonate_mdcG:Global:Membrane Transport:Environmental Information Processing:Amino Acid Metabolism:Lipid Metabolism:Energy Metabolism:Biosynthesis of cofactors, prosthetic groups, and carriers:Carbohydrate Metabolism:Other:Signal transduction:PTS:Information storage and processing:Cellular processes and signaling:Metabolism:Poorly characterized:Nucleosides, purines and pyrimidines:Cations and iron carrying compounds:Carbohydrates, organic alcohols, and acids:Transport and binding proteins:Other:Energy metabolism:Metabolism:Metabolism" 25 "ABC-type phosphate transport system, periplasmic component:Phosphate/sulphate permeases:Amino acid transporters:Predicted phosphatase/phosphohexomutase:Predicted membrane protein:Sugar phosphate permease:Cyanate permease:P pilus assembly protein, chaperone PapD:Amino acid transport and metabolism:Carbohydrate transport and metabolism:Cell motility:Inorganic ion transport and metabolism:Bisphenol degradation:Microbial metabolism in diverse environments:Bacterial secretion system:General function prediction only:Function unknown:lucif_BA3436:Intracellular trafficking, secretion, and vesicular transport:Membrane Transport:Environmental Information Processing:Enzymes of unknown specificity:Xenobiotics Biodegradation and Metabolism:Cellular processes and signaling:Metabolism:Poorly characterized:Metabolism:Unknown function:Metabolism:Global" 26 "Energy production and conversion:Predicted Na+-dependent transporter:Thiamine biosynthesis protein ThiC:Predicted oxidoreductases (related to aryl-alcohol dehydrogenases):Predicted GTPases (dynamin-related):Threonine dehydrogenase and related Zn-dependent dehydrogenases:Choline-glycine betaine transporter:Transcriptional regulator:HrpA-like helicases:Protein-disulfide isomerase:Beta-lactamase class C and other penicillin binding proteins:Peroxiredoxin:Predicted protein-tyrosine phosphatase:Cytochrome B561:Uncharacterized protein, possibly involved in glyoxylate utilization:Predicted lactoylglutathione lyase:Outer membrane receptor for Fe3+-dicitrate:Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain:Amino acid transport and metabolism:Coenzyme transport and metabolism:Transcription:Replication, recombination and repair:Cell wall/membrane/envelope biogenesis:Posttranslational modification, protein turnover, chaperones:Inorganic ion transport and metabolism:Thiamine metabolism:Metabolic pathways:General function prediction only:Signal transduction mechanisms:thiC:bcct:TonB-siderophor:DEAH_box_HrpB:ura-cupin:Defense mechanisms:Biosynthesis of cofactors, prosthetic groups, and carriers:Enzymes of unknown specificity:Unknown function:Porins:Other:Transport and binding proteins:Metabolism:Global:Metabolism:Metabolism of Cofactors and Vitamins:Poorly characterized:Metabolism:Cellular processes and signaling:Information storage and processing:Thiamine" 27 "Predicted membrane protein:DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog:Uncharacterized conserved protein:Uncharacterized protein conserved in bacteria:Poly(3-hydroxybutyrate) depolymerase:Transcription:RNA polymerase:Secondary metabolites biosynthesis, transport and catabolism:Function unknown:yihY_not_rbn:sigma70-ECF:Poorly characterized:Transcription:Unknown function:General:Information storage and processing:Metabolism:Genetic Information Processing" 28 "Energy production and conversion:Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase]:FAD/FMN-containing dehydrogenases:Predicted Zn-dependent proteases and their inactivated homologs:Predicted amidohydrolase:Nucleotide-binding protein implicated in inhibition of septum formation:Enoyl-CoA hydratase/carnithine racemase:Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases):ABC-type proline/glycine betaine transport systems, ATPase components:ABC-type proline/glycine betaine transport systems, permease component:Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes:Na+/phosphate symporter:Transcriptional regulator:Ribonucleases G and E:Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase:Periplasmic glycine betaine/choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein):Uncharacterized protein, possibly involved in aromatic compounds catabolism:Uncharacterized conserved protein:Uncharacterized protein involved in outer membrane biogenesis:Predicted membrane protein:Small-conductance mechanosensitive channel:Cell cycle control, cell division, chromosome partitioning:Amino acid transport and metabolism:Coenzyme transport and metabolism:Lipid transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:Cell wall/membrane/envelope biogenesis:Inorganic ion transport and metabolism:Glycolysis / Gluconeogenesis:Citrate cycle (TCA cycle):Fatty acid biosynthesis:Fatty acid metabolism:Glycine serine and threonine metabolism:Valine leucine and isoleucine degradation:Geraniol degradation:Lysine degradation:Benzoate degradation:Tryptophan metabolism:beta-Alanine metabolism:Ether lipid metabolism:Pyruvate metabolism:Aminobenzoate degradation:Propanoate metabolism:Butanoate metabolism:Limonene and pinene degradation:Caprolactam degradation:Biosynthesis of unsaturated fatty acids:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:ABC transporters:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:Function unknown:TIGR00147:maf:unchar_dom_1:NaPi_cotrn_rel:RNaseEG:proV:lipoamide_DH:TIGR02099:Metabolism:Carbohydrate Metabolism:Lipid Metabolism:Amino Acid Metabolism:Metabolism of Other Amino Acids:Metabolism of Terpenoids and Polyketides:Xenobiotics Biodegradation and Metabolism:Environmental Information Processing:Membrane Transport:Global:Metabolism:Transcription:Degradation of RNA:Transport and binding proteins:Amino acids, peptides and amines:Cations and iron carrying compounds:Cellular processes:Cell division:Hypothetical proteins:Conserved:Unknown function:Enzymes of unknown specificity:Information storage and processing:Cellular processes and signaling:Metabolism:Poorly characterized" 29 "Energy production and conversion:F0F1-type ATP synthase, beta subunit:F0F1-type ATP synthase, alpha subunit:F0F1-type ATP synthase, gamma subunit:F0F1-type ATP synthase, subunit a:F0F1-type ATP synthase, subunit b:F0F1-type ATP synthase, delta subunit (mitochondrial oligomycin sensitivity protein):Rieske Fe-S protein:Cytochrome b subunit of the bc complex:Cytochrome c1:Oxidative phosphorylation:Metabolic pathways:atpA:atpD:ATP_synt_6_or_A:ATP_synt_b:ATP_synt_delta:ATPsyn_F1gamma:ATP_synt_c:Rieske_proteo:Energy metabolism:Energy Metabolism:Global:Metabolism:Metabolism:ATP-proton motive force interconversion:Electron transport:Metabolism" 30 "Lactoylglutathione lyase and related lyases:Methylated DNA-protein cysteine methyltransferase:Acetyltransferases:Glycerol uptake facilitator and related permeases (Major Intrinsic Protein Family):Transcriptional regulator:Uncharacterized homolog of gamma-carboxymuconolactone decarboxylase subunit:Predicted ATPase with chaperone activity:Predicted permease:Predicted transcriptional regulators:Predicted permeases:Hydrolases of the alpha/beta superfamily:Uncharacterized conserved protein:Membrane protein implicated in regulation of membrane protease activity:Mn2+ and Fe2+ transporters of the NRAMP family:Chromate transport protein ChrA:AraC-type DNA-binding domain-containing proteins:Predicted membrane protein:Uncharacterized conserved protein:Predicted membrane protein:Amino acid transport and metabolism:Carbohydrate transport and metabolism:Transcription:Replication, recombination and repair:Posttranslational modification, protein turnover, chaperones:Inorganic ion transport and metabolism:Fatty acid metabolism:Benzoate degradation:Metabolic pathways:Microbial metabolism in diverse environments:General function prediction only:Function unknown:TIGR00368:ogt:TIGR00698:MIP:2A51:nramp:Intracellular trafficking, secretion, and vesicular transport:Poorly characterized:Metabolism:Cellular processes and signaling:Information storage and processing:General:Unknown function:Conserved:Hypothetical proteins:Cations and iron carrying compounds:Anions:Unknown substrate:Transport and binding proteins:DNA replication, recombination, and repair:DNA metabolism:Metabolism:Metabolism:Global:Xenobiotics Biodegradation and Metabolism:Lipid Metabolism" 31 "Energy production and conversion:Ribosomal protein L5:FAD/FMN-containing dehydrogenases:Predicted integral membrane protein:Uncharacterized conserved protein:Zn-dependent hydrolases, including glyoxylases:Predicted metal-dependent phosphoesterases (PHP family):Spermidine/putrescine-binding periplasmic protein:Uncharacterized protein involved in formate dehydrogenase formation:ABC-type molybdate transport system, ATPase component:Predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, ATPase component:Predicted signal transduction protein containing sensor and EAL domains:Amino acid transport and metabolism:Translation, ribosomal structure and biogenesis:Posttranslational modification, protein turnover, chaperones:Inorganic ion transport and metabolism:Aminoacyl-tRNA biosynthesis:ABC transporters:Ribosome:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:Function unknown:Signal transduction mechanisms:TIGR00374:TAT_signal_seq:FdhE:YD_repeat_2x:modC_ABC:Poorly characterized:Translation:Environmental Information Processing:Membrane Transport:Protein fate:Protein and peptide secretion and trafficking:Transport and binding proteins:Anions:Hypothetical proteins:Conserved:Information storage and processing:Cellular processes and signaling:Metabolism:Genetic Information Processing" 32 "Energy production and conversion:NADH:ubiquinone oxidoreductase 20 kD subunit and related Fe-S oxidoreductases:NADH:ubiquinone oxidoreductase 49 kD subunit 7:NADH:ubiquinone oxidoreductase subunit 11 or 4L (chain K):NADH:ubiquinone oxidoreductase subunit 6 (chain J):NADH:ubiquinone oxidoreductase subunit 1 (chain H):NADH:ubiquinone oxidoreductase subunit 2 (chain N):NADH:ubiquinone oxidoreductase subunit 4 (chain M):NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit:NADH dehydrogenase/NADH:ubiquinone oxidoreductase 75 kD subunit (chain G):Formate hydrogenlyase subunit 6/NADH:ubiquinone oxidoreductase 23 kD subunit (chain I):NADH:ubiquinone oxidoreductase, NADH-binding (51 kD) subunit:NADH:ubiquinone oxidoreductase 24 kD subunit:Inorganic ion transport and metabolism:Oxidative phosphorylation:Metabolic pathways:NDH_I_N:nuoB_fam:nuoE_fam:nuoF_fam:NuoC_fam:NuoI:NDH_I_M:NuoG:NDH_I_L:Electron transport:Energy Metabolism:Global:Metabolism:Energy metabolism:Metabolism:Metabolism" 33 "Serine/threonine protein kinase:Transcriptional regulator:Predicted permeases:Periplasmic component of the Tol biopolymer transport system:ABC-type polar amino acid transport system, ATPase component:Amidases related to nicotinamidase:Uncharacterized protein, possibly involved in aromatic compounds catabolism:Probable taurine catabolism dioxygenase:AraC-type DNA-binding domain-containing proteins:Nitrate/nitrite transporter:Pyoverdine/dityrosine biosynthesis protein:Transcriptional regulator of aromatic amino acids metabolism:Uncharacterized protein conserved in bacteria:Ketosteroid isomerase homolog:Outer membrane receptor for Fe3+-dicitrate:Amino acid transport and metabolism:Transcription:Replication, recombination and repair:Inorganic ion transport and metabolism:Aminoacyl-tRNA biosynthesis:ABC transporters:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:Function unknown:Signal transduction mechanisms:unchar_dom_1:TonB-siderophor:TIGR02246:XapX:Intracellular trafficking, secretion, and vesicular transport:Genetic Information Processing:Poorly characterized:Metabolism:Cellular processes and signaling:Information storage and processing:General:Unknown function:Porins:Transport and binding proteins:Membrane Transport:Environmental Information Processing:Translation" 34 "Energy production and conversion:Predicted amidohydrolase:Transcriptional regulator:Uncharacterized membrane-associated protein:cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases:ABC-type branched-chain amino acid transport systems, periplasmic component:ABC-type amino acid transport/signal transduction systems, periplasmic component/domain:Putative threonine efflux protein:Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases:FOG: GGDEF domain:AraC-type DNA-binding domain-containing proteins:Uncharacterized protein conserved in bacteria:Uncharacterized conserved protein:Response regulator with putative antiterminator output domain:Predicted membrane protein:Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain:Amino acid transport and metabolism:Transcription:Arginine and proline metabolism:Phenylalanine metabolism:Tryptophan metabolism:Cyanoamino acid metabolism:Aminobenzoate degradation:Styrene degradation:Microbial metabolism in diverse environments:ABC transporters:General function prediction only:Function unknown:Signal transduction mechanisms:sensory_box:TIGR02096:TIGR02270:FMN_nitrolo:Hypothetical proteins:Small molecule interactions:Regulatory functions:Metabolism:Global:Metabolism:Membrane Transport:Environmental Information Processing:Xenobiotics Biodegradation and Metabolism:Metabolism of Other Amino Acids:Information storage and processing:Amino Acid Metabolism:Cellular processes and signaling:Metabolism:Poorly characterized:Enzymes of unknown specificity:Unknown function:Conserved" 35 "Energy production and conversion:Cysteine synthase:Cystathionine beta-lyases/cystathionine gamma-synthases:2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases:Predicted transcriptional regulators:Type II secretory pathway, component PulD:Type II secretory pathway, component PulF:Inosine-uridine nucleoside N-ribohydrolase:Type II secretory pathway, pseudopilin PulG:Type II secretory pathway, ATPase PulE/Tfp pilus assembly pathway, ATPase PilB:Type II secretory pathway, component PulM:Type II secretory pathway, component PulK:Type II secretory pathway, component PulL:Bacteriophytochrome (light-regulated signal transduction histidine kinase):Uncharacterized protein with a C-terminal OMP (outer membrane protein) domain:Type II secretory pathway, component PulJ:Amino acid transport and metabolism:Nucleotide transport and metabolism:Coenzyme transport and metabolism:Transcription:Cell motility:Purine metabolism:Glycine serine and threonine metabolism:Cysteine and methionine metabolism:Selenocompound metabolism:Nicotinate and nicotinamide metabolism:Nitrogen metabolism:Metabolic pathways:Bacterial secretion system:Function unknown:Signal transduction mechanisms:autotrans_barl:gspI:typeII_sec_gspH:typeII_sec_gspL:typeII_sec_gspG:gspJ:CueR:GspF:type_II_gspD:type_II_gspE:Intracellular trafficking, secretion, and vesicular transport:Membrane Transport:Environmental Information Processing:Metabolism of Cofactors and Vitamins:Metabolism of Other Amino Acids:Amino Acid Metabolism:Nucleotide Metabolism:DNA interactions:Energy Metabolism:Protein fate:Protein and peptide secretion and trafficking:Cellular processes:Pathogenesis:Information storage and processing:Cellular processes and signaling:Metabolism:Poorly characterized:Regulatory functions:Metabolism:Global:Metabolism" 36 "Energy production and conversion:Glutamate-1-semialdehyde aminotransferase:Acetyl-CoA acetyltransferase:Amino acid transporters:Glycine/D-amino acid oxidases (deaminating):NAD-dependent aldehyde dehydrogenases:Enoyl-CoA hydratase/carnithine racemase:Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases):ABC-type transport system involved in multi-copper enzyme maturation, permease component:Arginine/lysine/ornithine decarboxylases:FOG: EAL domain:Choline dehydrogenase and related flavoproteins:P pilus assembly protein, chaperone PapD:P pilus assembly protein, porin PapC:ABC-type arginine transport system, permease component:Amino acid transport and metabolism:Coenzyme transport and metabolism:Lipid transport and metabolism:Cell motility:Fatty acid biosynthesis:Fatty acid metabolism:Synthesis and degradation of ketone bodies:Valine leucine and isoleucine degradation:Geraniol degradation:Lysine degradation:Benzoate degradation:Tryptophan metabolism:beta-Alanine metabolism:Pyruvate metabolism:Aminobenzoate degradation:Glyoxylate and dicarboxylate metabolism:Propanoate metabolism:Butanoate metabolism:Carbon fixation pathways in prokaryotes:Porphyrin and chlorophyll metabolism:Terpenoid backbone biosynthesis:Limonene and pinene degradation:Caprolactam degradation:Biosynthesis of unsaturated fatty acids:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:ABC transporters:Two-component system:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:Signal transduction mechanisms:HEQRo_perm_3TM:AcCoA-C-Actrans:Intracellular trafficking, secretion, and vesicular transport:Transport and binding proteins:Carbohydrate Metabolism:Energy Metabolism:Lipid Metabolism:Amino Acid Metabolism:Metabolism of Other Amino Acids:Metabolism of Cofactors and Vitamins:Metabolism of Terpenoids and Polyketides:Xenobiotics Biodegradation and Metabolism:Environmental Information Processing:Membrane Transport:Signal Transduction:Global:Metabolism:Fatty acid and phospholipid metabolism:Other:Metabolism:Amino acids, peptides and amines:Cellular processes and signaling:Metabolism:Poorly characterized" 37 "Cytidylate kinase:Predicted Zn-dependent peptidases:Enoyl-[acyl-carrier-protein] reductase (NADH):N6-adenine-specific methylase:ABC-type multidrug transport system, permease component:ABC-type multidrug transport system, ATPase component:Pyridoxal phosphate biosynthesis protein:DNA polymerase III, chi subunit:Outer membrane lipoprotein involved in outer membrane biogenesis:Uncharacterized protein conserved in bacteria:ABC-type uncharacterized transport system, duplicated ATPase component:ABC-type uncharacterized transport system, permease component:ABC-type uncharacterized transport system, permease component:Putative Mg2+ and Co2+ transporter CorC:Nucleotide transport and metabolism:Coenzyme transport and metabolism:Lipid transport and metabolism:Replication, recombination and repair:Cell wall/membrane/envelope biogenesis:Inorganic ion transport and metabolism:Fatty acid biosynthesis:Purine metabolism:Pyrimidine metabolism:Vitamin B6 metabolism:Metabolic pathways:ABC transporters:DNA replication:Mismatch repair:Homologous recombination:General function prediction only:Function unknown:cmk:TIGR00095:lolB:pdxA:Defense mechanisms:Metabolism:Poorly characterized:Metabolism:Cellular processes and signaling:Information storage and processing:Pyridoxine:Biosynthesis of cofactors, prosthetic groups, and carriers:Protein and peptide secretion and trafficking:Protein fate:tRNA and rRNA base modification:Protein synthesis:Nucleotide and nucleoside interconversions:Purines, pyrimidines, nucleosides, and nucleotides:Metabolism:Global:Membrane Transport:Environmental Information Processing:Replication and Repair:Genetic Information Processing:Metabolism of Cofactors and Vitamins:Nucleotide Metabolism:Lipid Metabolism" 38 "Energy production and conversion:Ornithine carbamoyltransferase:Carbamate kinase:Universal stress protein UspA and related nucleotide-binding proteins:ABC-type multidrug transport system, permease component:BioD-like N-terminal domain of phosphotransacetylase:ATPase components of various ABC-type transport systems, contain duplicated ATPase:Predicted exonuclease of the beta-lactamase fold involved in RNA processing:Multidrug resistance efflux pump:Predicted Rossmann fold nucleotide-binding protein:Transcriptional regulators:Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain:Arginine deiminase:Arabinose efflux permease:Cytochrome c:Phosphoketolase:Amino acid transport and metabolism:Carbohydrate transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:Purine metabolism:Arginine and proline metabolism:Taurine and hypotaurine metabolism:Pyruvate metabolism:Propanoate metabolism:Methane metabolism:Carbon fixation pathways in prokaryotes:Nitrogen metabolism:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:ABC transporters:Two-component system:General function prediction only:Signal transduction mechanisms:pta:orni_carb_tr:arcC:arcA:Defense mechanisms:Metabolism:Metabolism:Global:Signal Transduction:Membrane Transport:Environmental Information Processing:Metabolism of Other Amino Acids:Amino Acid Metabolism:Nucleotide Metabolism:Energy Metabolism:Amino acid biosynthesis:Carbohydrate Metabolism:Glutamate family:Information storage and processing:Cellular processes and signaling:Metabolism:Poorly characterized:Fermentation:Amino acids and amines:Energy metabolism" 39 "ATPase components of ABC transporters with duplicated ATPase domains:Na+/proline symporter:ABC-type amino acid transport/signal transduction systems, periplasmic component/domain:Cation/multidrug efflux pump:Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases):Predicted ATPase:Lauroyl/myristoyl acyltransferase:Outer membrane receptor proteins, mostly Fe transport:Pirin-related protein:Xanthine and CO dehydrogenases maturation factor, XdhC/CoxF family:ABC-type metal ion transport system, permease component:Transcriptional regulators:FOG: GGDEF domain:Xanthine/uracil permeases:Predicted nucleotidyltransferase:Amino acid transport and metabolism:Nucleotide transport and metabolism:Lipid transport and metabolism:Transcription:Cell wall/membrane/envelope biogenesis:Posttranslational modification, protein turnover, chaperones:Inorganic ion transport and metabolism:Lipopolysaccharide biosynthesis:Metabolic pathways:ABC transporters:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:Signal transduction mechanisms:sensory_box:ncs2:2A0602:adhes_NPXG:lipid_A_htrB:xanthine_xdhC:Defense mechanisms:Poorly characterized:Glycan Biosynthesis and Metabolism:Environmental Information Processing:Membrane Transport:Global:Metabolism:Purines, pyrimidines, nucleosides, and nucleotides:Other:Regulatory functions:Small molecule interactions:Transport and binding proteins:Unknown substrate:Nucleosides, purines and pyrimidines:Cell envelope:Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides:Information storage and processing:Cellular processes and signaling:Metabolism:Metabolism" 40 "Pseudouridylate synthases, 23S RNA-specific:Coproporphyrinogen III oxidase and related Fe-S oxidoreductases:Uncharacterized membrane protein, putative virulence factor:Amino acid transporters:Branched-chain amino acid permeases:ABC-type multidrug transport system, ATPase and permease components:Phosphatidylglycerophosphatase A and related proteins:Transcriptional regulators of sugar metabolism:Purine-cytosine permease and related proteins:TRAP-type C4-dicarboxylate transport system, periplasmic component:Uncharacterized membrane protein, required for spore maturation in B.subtilis.:Small-conductance mechanosensitive channel:Na+/serine symporter:Uncharacterized membrane protein affecting hemolysin expression:Predicted membrane protein:Predicted membrane protein:Kef-type K+ transport system, predicted NAD-binding component:Amino acid transport and metabolism:Nucleotide transport and metabolism:Carbohydrate transport and metabolism:Coenzyme transport and metabolism:Lipid transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:Cell wall/membrane/envelope biogenesis:Inorganic ion transport and metabolism:Peptidoglycan biosynthesis:Glycerophospholipid metabolism:Porphyrin and chlorophyll metabolism:Metabolic pathways:Biosynthesis of secondary metabolites:ABC transporters:General function prediction only:Function unknown:TIGR00452:hemN_rel:dctP:livcs:2a37:mviN:metW:Defense mechanisms:Information storage and processing:Lipid Metabolism:Glycan Biosynthesis and Metabolism:Metabolism of Cofactors and Vitamins:Environmental Information Processing:Membrane Transport:Global:Metabolism:Transport and binding proteins:Amino acids, peptides and amines:Carbohydrates, organic alcohols, and acids:Cations and iron carrying compounds:Unknown function:Enzymes of unknown specificity:General:Amino acid biosynthesis:Aspartate family:Biosynthesis of cofactors, prosthetic groups, and carriers:Heme, porphyrin, and cobalamin:Metabolism:Cellular processes and signaling:Metabolism:Poorly characterized" 41 "Predicted redox protein, regulator of disulfide bond formation:Orotate phosphoribosyltransferase:Glutaredoxin and related proteins:Exonuclease III:Uncharacterized conserved protein:FKBP-type peptidyl-prolyl cis-trans isomerases 2:ADP-ribose pyrophosphatase:Uncharacterized membrane protein, required for colicin V production:DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog:Transcriptional regulators:Uncharacterized protein conserved in bacteria:Predicted metal-binding protein related to the C-terminal domain of SecA:Predicted small periplasmic lipoprotein:Nucleotide transport and metabolism:Transcription:Replication, recombination and repair:Cell motility:Posttranslational modification, protein turnover, chaperones:Pyrimidine metabolism:Metabolic pathways:RNA polymerase:Base excision repair:Sulfur relay system:General function prediction only:Function unknown:TIGR00278:pyrE:xth:ygfB_yecA:PHA_gran_rgn:sigma70-ECF:Unknown function:Nucleotide Metabolism:Genetic Information Processing:Transcription:Folding Sorting and Degradation:Replication and Repair:Global:Metabolism:Purines, pyrimidines, nucleosides, and nucleotides:Pyrimidine ribonucleotide biosynthesis:DNA metabolism:DNA replication, recombination, and repair:Hypothetical proteins:Conserved:Metabolism:General:Information storage and processing:Cellular processes and signaling:Metabolism:Poorly characterized" 42 "Xaa-Pro aminopeptidase:Diaminopimelate decarboxylase:Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase]:Dihydroxyacid dehydratase/phosphogluconate dehydratase:Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases:Diaminopimelate epimerase:Lipoate-protein ligase B:ATPase components of ABC transporters with duplicated ATPase domains:Glycine cleavage system H protein (lipoate-binding):Predicted hydrolase (HAD superfamily):Acyl dehydratase:Uncharacterized conserved protein:Lysophospholipase:Transcriptional regulator:Putative lipoprotein:Short-chain alcohol dehydrogenase of unknown specificity:Amino acid transport and metabolism:Carbohydrate transport and metabolism:Coenzyme transport and metabolism:Lipid transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:Valine leucine and isoleucine biosynthesis:Lysine biosynthesis:Arginine and proline metabolism:Phenylalanine metabolism:Tryptophan metabolism:Cyanoamino acid metabolism:Aminobenzoate degradation:Styrene degradation:Butanoate metabolism:C5-Branched dibasic acid metabolism:Pantothenate and CoA biosynthesis:Lipoic acid metabolism:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:General function prediction only:Function unknown:ilvD:lipB:gcvH:DapF:lysA:HAD-SF-IA-v3:ABC_ABC_ChvD:Poorly characterized:Metabolism:Information storage and processing:Pyruvate family:Aspartate family:Amino acid biosynthesis:Enzymes of unknown specificity:Metabolism:Global:Unknown function:Metabolism:Xenobiotics Biodegradation and Metabolism:Protein modification and repair:Protein fate:Metabolism of Cofactors and Vitamins:Metabolism of Other Amino Acids:Amino Acid Metabolism:Amino acids and amines:Energy metabolism:Carbohydrate Metabolism" 43 "Energy production and conversion:Isoleucyl-tRNA synthetase:Predicted EndoIII-related endonuclease:Threonine synthase:GMP synthase, PP-ATPase domain/subunit:Lipoprotein signal peptidase:Predicted unusual protein kinase:Penicillin tolerance protein:ABC-type polar amino acid transport system, ATPase component:Transcription-repair coupling factor (superfamily II helicase):Na+-transporting NADH:ubiquinone oxidoreductase, subunit NqrB:Na+-transporting NADH:ubiquinone oxidoreductase, subunit NqrF:Uncharacterized protein conserved in bacteria:Uncharacterized protein involved in biosynthesis of c-type cytochromes:Heme exporter protein D:Cytochrome c biogenesis factor:Predicted NADH:ubiquinone oxidoreductase, subunit RnfC:Predicted NADH:ubiquinone oxidoreductase, subunit RnfD:Amino acid transport and metabolism:Nucleotide transport and metabolism:Lipid transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:Replication, recombination and repair:Cell wall/membrane/envelope biogenesis:Posttranslational modification, protein turnover, chaperones:Ubiquinone and other terpenoid-quinone biosynthesis:Purine metabolism:Glycine serine and threonine metabolism:Valine leucine and isoleucine biosynthesis:Vitamin B6 metabolism:Terpenoid backbone biosynthesis:Aminoacyl-tRNA biosynthesis:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:ABC transporters:Protein export:Base excision repair:Nucleotide excision repair:General function prediction only:Function unknown:lspA:ispH_lytB:thrC:ileS:mfd:guaA_Cterm:nth:nqrB:nqrF:rnfC:rnfD:UbiB:cytochro_ccmD:cytochro_ccmI:Intracellular trafficking, secretion, and vesicular transport:Other:Nucleotide Metabolism:Amino Acid Metabolism:Metabolism of Cofactors and Vitamins:Metabolism of Terpenoids and Polyketides:Genetic Information Processing:Translation:Folding Sorting and Degradation:Replication and Repair:Environmental Information Processing:Membrane Transport:Global:Metabolism:Energy metabolism:Electron transport:Purines, pyrimidines, nucleosides, and nucleotides:Purine ribonucleotide biosynthesis:DNA metabolism:DNA replication, recombination, and repair:Protein synthesis:tRNA aminoacylation:Protein fate:Protein and peptide secretion and trafficking:Transport and binding proteins:Cations and iron carrying compounds:Amino acid biosynthesis:Aspartate family:Biosynthesis of cofactors, prosthetic groups, and carriers:Metabolism:Menaquinone and ubiquinone:Information storage and processing:Cellular processes and signaling:Metabolism:Poorly characterized" 44 "Lactoylglutathione lyase and related lyases:Acetyltransferases:Transcriptional regulator:Predicted permeases:Predicted transcriptional regulators:Urease accessory protein UreF:Putative threonine efflux protein:Transcriptional regulator:Uncharacterized conserved protein:Transcriptional regulators:Membrane protein implicated in regulation of membrane protease activity:Predicted transcriptional regulator:Uncharacterized protein conserved in bacteria:Phosphopantetheinyl transferase component of siderophore synthetase:PAP2 (acid phosphatase) superfamily protein:Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta):Amino acid transport and metabolism:Lipid transport and metabolism:Transcription:Posttranslational modification, protein turnover, chaperones:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:Function unknown:Intracellular trafficking, secretion, and vesicular transport:Poorly characterized:Metabolism:Cellular processes and signaling:Information storage and processing" 45 "ATPases with chaperone activity, ATP-binding subunit:Uncharacterized protein conserved in bacteria:Uncharacterized protein conserved in bacteria:Uncharacterized protein conserved in bacteria:Uncharacterized protein conserved in bacteria:Protein of avirulence locus involved in temperature-dependent protein secretion:Posttranslational modification, protein turnover, chaperones:Aminoacyl-tRNA biosynthesis:Bacterial secretion system:General function prediction only:Function unknown:vgr_GE:VI_ClpV1:VI_chp_1:VI_zyme:VI_chp_6:Pathogenesis:Translation:Environmental Information Processing:Membrane Transport:Cellular processes:Genetic Information Processing:Cellular processes and signaling:Poorly characterized" 46 "Energy production and conversion:Sulfite reductase, beta subunit (hemoprotein):Polyferredoxin:ATPases with chaperone activity, ATP-binding subunit:Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs:Cytochrome bd-type quinol oxidase, subunit 1:Cytochrome bd-type quinol oxidase, subunit 2:Cation transport ATPase:Uncharacterized protein conserved in bacteria:Uncharacterized protein, possibly involved in nitrogen fixation:Uncharacterized protein conserved in bacteria:Cbb3-type cytochrome oxidase, subunit 1:Uncharacterized protein conserved in bacteria:Amino acid transport and metabolism:Transcription:Posttranslational modification, protein turnover, chaperones:Inorganic ion transport and metabolism:Oxidative phosphorylation:Sulfur metabolism:Metabolic pathways:Microbial metabolism in diverse environments:Function unknown:cydB:ccoN:ccoS:ATPase_P-type:ccoG_rdxA_fixG:AZL_007950_fam:Metabolism:Energy Metabolism:Global:Metabolism:Energy metabolism:Electron transport:Protein fate:Protein modification and repair:Information storage and processing:Cellular processes and signaling:Metabolism:Poorly characterized" 47 "Energy production and conversion:Dihydroorotase and related cyclic amidohydrolases:Delta-aminolevulinic acid dehydratase:Seryl-tRNA synthetase:Glutamine synthetase:Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component, and related enzymes:Aspartate carbamoyltransferase, catalytic chain:Methyl-accepting chemotaxis protein:Cation/multidrug efflux pump:Polyphosphate kinase:Outer membrane protein:Pyrimidine operon attenuation protein/uracil phosphoribosyltransferase:Pyruvate dehydrogenase complex, dehydrogenase (E1) component:Acetyl/propionyl-CoA carboxylase, alpha subunit:Pyruvate/oxaloacetate carboxyltransferase:Amino acid transport and metabolism:Nucleotide transport and metabolism:Coenzyme transport and metabolism:Lipid transport and metabolism:Translation, ribosomal structure and biogenesis:Cell wall/membrane/envelope biogenesis:Cell motility:Inorganic ion transport and metabolism:Glycolysis / Gluconeogenesis:Citrate cycle (TCA cycle):Oxidative phosphorylation:Pyrimidine metabolism:Alanine aspartate and glutamate metabolism:Valine leucine and isoleucine biosynthesis:Arginine and proline metabolism:Pyruvate metabolism:Butanoate metabolism:Porphyrin and chlorophyll metabolism:Nitrogen metabolism:Aminoacyl-tRNA biosynthesis:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:Two-component system:Bacterial chemotaxis:RNA degradation:Signal transduction mechanisms:sensory_box:serS:accC:GlnA:asp_carb_tr:aceE:pyrC_multi:2A0602:oadA:PDHac_trf_long:outer_NodT:poly_P_kin:Intracellular trafficking, secretion, and vesicular transport:Defense mechanisms:tRNA aminoacylation:Carbohydrate Metabolism:Energy Metabolism:Nucleotide Metabolism:Amino Acid Metabolism:Metabolism of Cofactors and Vitamins:Genetic Information Processing:Translation:Folding Sorting and Degradation:Environmental Information Processing:Signal Transduction:Cellular Processes:Cell Motility:Global:Metabolism:Central intermediary metabolism:Phosphorus compounds:Energy metabolism:Pyruvate dehydrogenase:Other:Fatty acid and phospholipid metabolism:Biosynthesis:Purines, pyrimidines, nucleosides, and nucleotides:Pyrimidine ribonucleotide biosynthesis:Regulatory functions:Small molecule interactions:Protein synthesis:Metabolism:Transport and binding proteins:Unknown substrate:Porins:Amino acid biosynthesis:Glutamate family:Information storage and processing:Cellular processes and signaling:Metabolism" 48 "ABC-type phosphate transport system, periplasmic component:Short-chain dehydrogenases of various substrate specificities:Na+-driven multidrug efflux pump:Phosphate uptake regulator:Methyl-accepting chemotaxis protein:ABC-type phosphate transport system, ATPase component:Uncharacterized membrane protein:Predicted transcriptional regulator:AraC-type DNA-binding domain-containing proteins:Predicted membrane protein:Uncharacterized conserved protein:Uncharacterized protein conserved in bacteria:Uncharacterized protein conserved in bacteria:Phosphate-selective porin:Predicted proline hydroxylase:Uncharacterized protein conserved in bacteria:ABC-type uncharacterized transport system, permease component:ABC-type phosphate transport system, auxiliary component:Transcription:Cell motility:Posttranslational modification, protein turnover, chaperones:Inorganic ion transport and metabolism:Aminoacyl-tRNA biosynthesis:ABC transporters:Two-component system:Bacterial chemotaxis:Ribosome:General function prediction only:Function unknown:Signal transduction mechanisms:matE:3a0107s01c2:3a0107s02c:phoU_full:ptsS_2:Defense mechanisms:Other:Anions:Transport and binding proteins:Information storage and processing:Cellular processes and signaling:Metabolism:Poorly characterized:Genetic Information Processing:Cell Motility:Cellular Processes:Signal Transduction:Membrane Transport:Environmental Information Processing:Translation" 49 "Energy production and conversion:Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), A subunit:Predicted Zn-dependent proteases and their inactivated homologs:Nuclease subunit of the excinuclease complex:Acetyltransferases:ATP-dependent exoDNAse (exonuclease V), alpha subunit - helicase superfamily I member:Glycine cleavage system H protein (lipoate-binding):Transcriptional regulator:Glycine/D-amino acid oxidases (deaminating):Lactate dehydrogenase and related dehydrogenases:ATP-dependent exoDNAse (exonuclease V) beta subunit (contains helicase and exonuclease domains):Threonine dehydratase:ABC-type Fe3+ transport system, permease component:Exonuclease V gamma subunit:Beta-glucosidase-related glycosidases:Cobalamin biosynthesis protein CbiD:4-diphosphocytidyl-2C-methyl-D-erythritol 2-phosphate synthase:Predicted peroxiredoxins:Precorrin-6x reductase:Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains:Precorrin-4 methylase:Selenocysteine-specific translation elongation factor:ABC-type oligopeptide transport system, periplasmic component:Signal transduction histidine kinase regulating C4-dicarboxylate transport system:Site-specific recombinase XerC:Amino acid transport and metabolism:Carbohydrate transport and metabolism:Coenzyme transport and metabolism:Lipid transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:Replication, recombination and repair:Inorganic ion transport and metabolism:Glycine serine and threonine metabolism:Valine leucine and isoleucine biosynthesis:Cyanoamino acid metabolism:Starch and sucrose metabolism:Pyruvate metabolism:Porphyrin and chlorophyll metabolism:Terpenoid backbone biosynthesis:Aminoacyl-tRNA biosynthesis:Metabolic pathways:Biosynthesis of secondary metabolites:ABC transporters:Two-component system:Nucleotide excision repair:Homologous recombination:General function prediction only:Signal transduction mechanisms:ispE:uvrC:small_GTP:cbiD:recB:parC_Gneg:recD:recC:cobM_cbiF:recomb_XerC:Other:Biosynthesis of cofactors, prosthetic groups, and carriers:General:Unknown function:DNA replication, recombination, and repair:DNA metabolism:Metabolism:Metabolism:Global:Signal Transduction:Membrane Transport:Environmental Information Processing:Replication and Repair:Translation:Genetic Information Processing:Metabolism of Terpenoids and Polyketides:Metabolism of Cofactors and Vitamins:Metabolism of Other Amino Acids:Amino Acid Metabolism:Poorly characterized:Carbohydrate Metabolism:Metabolism:Cellular processes and signaling:Information storage and processing:Heme, porphyrin, and cobalamin" 50 "Energy production and conversion:Phosphate/sulphate permeases:Transcriptional regulator:Predicted permeases:ABC-type amino acid transport system, permease component:Amino acid transporters:Flavodoxin reductases (ferredoxin-NADPH reductases) family 1:ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component:Outer membrane receptor proteins, mostly Fe transport:Uncharacterized protein, possibly involved in aromatic compounds catabolism:ABC-type oligopeptide transport system, periplasmic component:ABC-type uncharacterized transport system, permease component:Amino acid transport and metabolism:Transcription:Inorganic ion transport and metabolism:Aminobenzoate degradation:Microbial metabolism in diverse environments:ABC transporters:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:HEQRo_perm_3TM:Xenobiotics Biodegradation and Metabolism:Information storage and processing:Metabolism:Metabolism:Poorly characterized:Amino acids, peptides and amines:Transport and binding proteins:Metabolism:Global:Membrane Transport:Environmental Information Processing" 51 "RNA processing and modification:Energy production and conversion:2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway):Ribonuclease HI:Acetyltransferases:Zn-dependent hydrolases, including glyoxylases:NTP pyrophosphohydrolases including oxidative damage repair enzymes:DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32):Periplasmic serine proteases (ClpP class):Predicted transcriptional regulators:NADH dehydrogenase, FAD-containing subunit:Predicted esterase of the alpha-beta hydrolase superfamily:Oligoribonuclease (3'->5' exoribonuclease):Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains:Uncharacterized protein conserved in bacteria:PEP phosphonomutase and related enzymes:Molybdenum cofactor biosynthesis enzyme:Exonuclease I:Predicted metal-binding protein:Regulator of sigma D:Predicted membrane protein:Predicted periplasmic protein:Carbohydrate transport and metabolism:Coenzyme transport and metabolism:Transcription:Replication, recombination and repair:Posttranslational modification, protein turnover, chaperones:Oxidative phosphorylation:Pyruvate metabolism:RNA degradation:RNA polymerase:DNA replication:Mismatch repair:Sulfur relay system:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:Function unknown:Signal transduction mechanisms:rpoH_proteo:moaA:GSH_gloB:Intracellular trafficking, secretion, and vesicular transport:Biosynthesis of cofactors, prosthetic groups, and carriers:Detoxification:Cellular processes:Transcription factors:Transcription:Replication and Repair:Folding Sorting and Degradation:Transcription:Genetic Information Processing:Energy Metabolism:Carbohydrate Metabolism:Metabolism:Poorly characterized:Metabolism:Cellular processes and signaling:Information storage and processing:Molybdopterin" 52 "Energy production and conversion:Acetyl-CoA acetyltransferase:Signal transduction histidine kinase:Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain:Enoyl-CoA hydratase/carnithine racemase:Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases):Acyl-CoA synthetase (NDP forming):Transcriptional regulator:Beta-lactamase class C and other penicillin binding proteins:Acyl-CoA dehydrogenases:Acyl dehydratase:Dioxygenases related to 2-nitropropane dioxygenase:Predicted membrane protein:Sugar phosphate permease:Uncharacterized protein conserved in bacteria:Uncharacterized protein conserved in bacteria:Uncharacterized low-complexity protein:Carbohydrate transport and metabolism:Lipid transport and metabolism:Transcription:Fatty acid metabolism:Valine leucine and isoleucine degradation:Geraniol degradation:Lysine degradation:Penicillin and cephalosporin biosynthesis:Benzoate degradation:Tryptophan metabolism:beta-Alanine metabolism:Naphthalene degradation:Aminobenzoate degradation:Propanoate metabolism:Butanoate metabolism:Limonene and pinene degradation:Nitrogen metabolism:Caprolactam degradation:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:Two-component system:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:Function unknown:Signal transduction mechanisms:Defense mechanisms:Global:Signal Transduction:Environmental Information Processing:Xenobiotics Biodegradation and Metabolism:Biosynthesis of Other Secondary Metabolites:Metabolism of Terpenoids and Polyketides:Metabolism of Other Amino Acids:Amino Acid Metabolism:Lipid Metabolism:Energy Metabolism:Carbohydrate Metabolism:Poorly characterized:Metabolism:Cellular processes and signaling:Information storage and processing:Metabolism:Metabolism" 53 "Energy production and conversion:Formate-dependent phosphoribosylglycinamide formyltransferase (GAR transformylase):Glutathione synthase/Ribosomal protein S6 modification enzyme (glutaminyl transferase):Short-chain dehydrogenases of various substrate specificities:DNA repair exonuclease:Acetyltransferases:Glycine cleavage system H protein (lipoate-binding):Transcriptional regulator:Glycerophosphoryl diester phosphodiesterase:Signal transduction histidine kinase:ABC-type amino acid transport/signal transduction systems, periplasmic component/domain:ADP-ribose pyrophosphatase:Co/Zn/Cd efflux system component:Transglutaminase-like enzymes, putative cysteine proteases:DNA-binding protein, stimulates sugar fermentation:Outer membrane protein:Uncharacterized proteins, homologs of lactam utilization protein B:Acetyltransferases, including N-acetylases of ribosomal proteins:Transcriptional regulators:Acyl-CoA dehydrogenases:Allophanate hydrolase subunit 2:DNA repair proteins:Uncharacterized protein, possibly involved in aromatic compounds catabolism:Uncharacterized conserved protein:Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain:Chemotaxis response regulator containing a CheY-like receiver domain and a methylesterase domain:Putative NADPH-quinone reductase (modulator of drug activity B):Uncharacterized conserved protein:Uncharacterized conserved protein:Membrane protein required for beta-lactamase induction:Amino acid transport and metabolism:Nucleotide transport and metabolism:Coenzyme transport and metabolism:Lipid transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:Replication, recombination and repair:Cell wall/membrane/envelope biogenesis:Cell motility:Inorganic ion transport and metabolism:Fatty acid metabolism:Purine metabolism:Valine leucine and isoleucine degradation:Glycerophospholipid metabolism:Butanoate metabolism:One carbon pool by folate:Porphyrin and chlorophyll metabolism:Metabolic pathways:Biosynthesis of secondary metabolites:Two-component system:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:Function unknown:Signal transduction mechanisms:sfsA:radc:sbcd:PduO_Nterm:urea_amlyse_rel:rimK_fam:purT:CDF:outer_NodT:Intracellular trafficking, secretion, and vesicular transport:Defense mechanisms:Carbohydrate Metabolism:Cations and iron carrying compounds:Porins:Unknown function:General:Biosynthesis of cofactors, prosthetic groups, and carriers:Heme, porphyrin, and cobalamin:Information storage and processing:Cellular processes and signaling:Metabolism:Poorly characterized:Metabolism:DNA replication, recombination, and repair:DNA metabolism:Other:Regulatory functions:Purine ribonucleotide biosynthesis:Purines, pyrimidines, nucleosides, and nucleotides:Metabolism:Global:Signal Transduction:Environmental Information Processing:Metabolism of Cofactors and Vitamins:Amino Acid Metabolism:Nucleotide Metabolism:Lipid Metabolism:Transport and binding proteins" 54 "Membrane-fusion protein:Outer membrane protein:Flp pilus assembly protein TadC:ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain:Flp pilus assembly protein CpaB:Flp pilus assembly protein, pilin Flp:Signal transduction histidine kinase, nitrogen specific:Predicted membrane protein:Flp pilus assembly protein TadG:Flp pilus assembly protein, ATPase CpaF:Flp pilus assembly protein, ATPase CpaE:Flp pilus assembly protein, secretin CpaC:Flp pilus assembly protein TadD, contains TPR repeats:Cell wall/membrane/envelope biogenesis:Cell motility:ABC transporters:Function unknown:Signal transduction mechanisms:sensory_box:pilus_cpaB:type_I_sec_LssB:Intracellular trafficking, secretion, and vesicular transport:Defense mechanisms:Membrane Transport:Poorly characterized:Cellular processes and signaling:Pathogenesis:Cellular processes:Small molecule interactions:Regulatory functions:Environmental Information Processing" 55 "3-oxoacyl-(acyl-carrier-protein) synthase:Zn-dependent protease with chaperone function:MoxR-like ATPases:Uncharacterized membrane protein:Predicted membrane protein/domain:Uncharacterized conserved protein (some members contain a von Willebrand factor type A (vWA) domain):Uncharacterized protein conserved in bacteria:Uncharacterized conserved protein:Uncharacterized protein conserved in bacteria:Uncharacterized conserved protein:Lipid transport and metabolism:Posttranslational modification, protein turnover, chaperones:Fatty acid biosynthesis:Metabolic pathways:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:Function unknown:vgr_GE:Metabolism:Cellular processes and signaling:Metabolism:Global:Lipid Metabolism:Metabolism:Poorly characterized" 56 "Pseudouridine synthase:Transcription elongation factor:Thiamine biosynthesis ATP pyrophosphatase:Phosphoribosylpyrophosphate synthetase:Translation initiation factor 2 (IF-2; GTPase):Ribosome-binding factor A:Actin-like ATPase involved in cell morphogenesis:ABC-type metal ion transport system, ATPase component:Cell shape-determining protein:ABC-type metal ion transport system, permease component:Cell shape-determining protein:Cell cycle control, cell division, chromosome partitioning:Amino acid transport and metabolism:Nucleotide transport and metabolism:Coenzyme transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:Cell wall/membrane/envelope biogenesis:Inorganic ion transport and metabolism:Pentose phosphate pathway:Purine metabolism:Thiamine metabolism:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:ABC transporters:Sulfur relay system:rbfA:mreC:small_GTP:TIGR00342:TruB:mreB:ribP_PPkin:NusA:shape_MreD:Biosynthesis and degradation of murein sacculus and peptidoglycan:Carbohydrate Metabolism:Nucleotide Metabolism:Metabolism of Cofactors and Vitamins:Genetic Information Processing:Folding Sorting and Degradation:Environmental Information Processing:Membrane Transport:Global:Metabolism:Purines, pyrimidines, nucleosides, and nucleotides:Purine ribonucleotide biosynthesis:Transcription:Transcription factors:RNA processing:Protein synthesis:tRNA and rRNA base modification:Unknown function:General:Cell envelope:Metabolism:Information storage and processing:Cellular processes and signaling:Metabolism" 57 "Nitrogen regulatory protein PII:Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family:Carbonic anhydrases/acetyltransferases, isoleucine patch superfamily:ADP-ribose pyrophosphatase:ATP-dependent protease Clp, ATPase subunit:Cold shock proteins:Transcriptional regulator:Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor):Carbon storage regulator (could also regulate swarming and quorum sensing):DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog:Uncharacterized protein conserved in bacteria:Phosphotransferase system, HPr-related proteins:Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain:Predicted Fe-S protein:Amino acid transport and metabolism:Nucleotide transport and metabolism:Carbohydrate transport and metabolism:Transcription:Posttranslational modification, protein turnover, chaperones:Aminoacyl-tRNA biosynthesis:Two-component system:RNA polymerase:General function prediction only:Function unknown:Signal transduction mechanisms:csrA:clpX:PTS_HPr_family:TIGR02449:sigma70-ECF:Poorly characterized:Transcription:Translation:Environmental Information Processing:Signal Transduction:Regulatory functions:RNA interactions:Protein fate:Degradation of proteins, peptides, and glycopeptides:Signal transduction:PTS:Information storage and processing:Cellular processes and signaling:Metabolism:Genetic Information Processing" 58 "Energy production and conversion:Dihydrofolate reductase:Superfamily II DNA and RNA helicases:Glycerol-3-phosphate dehydrogenase:Transcriptional regulator:Predicted phosphatase/phosphohexomutase:Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain:Amino acid permeases:Flavodoxin reductases (ferredoxin-NADPH reductases) family 1:Mg-chelatase subunit ChlI:Putative effector of murein hydrolase LrgA:Predicted transcriptional regulators:AraC-type DNA-binding domain-containing proteins:Arabinose efflux permease:Uncharacterized protein conserved in bacteria:Uncharacterized protein conserved in bacteria:Uncharacterized conserved protein:Nicotinamide mononucleotide transporter:Transcriptional regulator containing GAF, AAA-type ATPase, and DNA binding domains:Predicted transcriptional regulator:Response regulator containing a CheY-like receiver domain and a GGDEF domain:Predicted aminopeptidase:Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain:Signal transduction histidine kinase involved in nitrogen fixation and metabolism regulation:Amino acid transport and metabolism:Carbohydrate transport and metabolism:Coenzyme transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:Replication, recombination and repair:One carbon pool by folate:Folate biosynthesis:Porphyrin and chlorophyll metabolism:Aminoacyl-tRNA biosynthesis:Metabolic pathways:Biosynthesis of secondary metabolites:Two-component system:General function prediction only:Function unknown:Signal transduction mechanisms:HAD-SF-IA-v3:NMN_trans_PnuC:Environmental Information Processing:Global:Translation:Genetic Information Processing:Metabolism:Unknown function:Metabolism of Cofactors and Vitamins:Metabolism:Poorly characterized:Metabolism:Cellular processes and signaling:Information storage and processing:Pyridine nucleotides:Biosynthesis of cofactors, prosthetic groups, and carriers:Signal Transduction:Enzymes of unknown specificity" 59 "Fructose-1,6-bisphosphatase:Glycosyltransferases involved in cell wall biogenesis:Zn-dependent hydrolases, including glyoxylases:Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases:Signal transduction histidine kinase:Bacterial cell division membrane protein:Holliday junction resolvasome, endonuclease subunit:Predicted phosphohydrolases:Transcriptional regulators:Transcriptional regulators:3-methyladenine DNA glycosylase:Nucleoid-associated protein:Uncharacterized protein conserved in bacteria:Predicted esterase:Uncharacterized protein conserved in bacteria:Heme oxygenase:Predicted aspartyl protease:Predicted periplasmic protein:Membrane carboxypeptidase/penicillin-binding protein:Cell cycle control, cell division, chromosome partitioning:Amino acid transport and metabolism:Carbohydrate transport and metabolism:Transcription:Replication, recombination and repair:Cell wall/membrane/envelope biogenesis:Inorganic ion transport and metabolism:Glycolysis / Gluconeogenesis:Pentose phosphate pathway:Fructose and mannose metabolism:Lysine biosynthesis:Peptidoglycan biosynthesis:Methane metabolism:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:Homologous recombination:General function prediction only:Function unknown:Signal transduction mechanisms:ruvC:dapE_proteo:PBP_1a_fam:rodA_shape:clan_AA_DTGA:Protein fate:DNA replication, recombination, and repair:DNA metabolism:Metabolism:Metabolism:Global:Replication and Repair:Genetic Information Processing:Glycan Biosynthesis and Metabolism:Amino Acid Metabolism:Energy Metabolism:Biosynthesis and degradation of murein sacculus and peptidoglycan:Carbohydrate Metabolism:Information storage and processing:Cellular processes and signaling:Metabolism:Poorly characterized:Cell envelope:Aspartate family:Amino acid biosynthesis:Cell division:Cellular processes:Degradation of proteins, peptides, and glycopeptides" 60 "Energy production and conversion:Uracil phosphoribosyltransferase:Predicted GTPase:SAM-dependent methyltransferases:Superfamily II DNA/RNA helicases, SNF2 family:Transcriptional regulator:Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter, MnhD subunit:MoxR-like ATPases:ABC-type transport system involved in resistance to organic solvents, permease component:Multisubunit Na+/H+ antiporter, MnhC subunit:NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit:Predicted membrane protein:Multisubunit Na+/H+ antiporter, MnhG subunit:Exonuclease V gamma subunit:Methylase of chemotaxis methyl-accepting proteins:Cobalamin biosynthesis protein CobN and related Mg-chelatases:Multisubunit Na+/H+ antiporter, MnhE subunit:Multisubunit Na+/H+ antiporter, MnhF subunit:Xanthine/uracil permeases:Uncharacterized protein containing a von Willebrand factor type A (vWA) domain:Leu/Phe-tRNA-protein transferase:16S RNA G1207 methylase RsmC:Flagellar biosynthesis chaperone:Uncharacterized protein conserved in bacteria:Predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, permease component:Small-conductance mechanosensitive channel:Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain:Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain:Nucleotide transport and metabolism:Coenzyme transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:Replication, recombination and repair:Cell wall/membrane/envelope biogenesis:Cell motility:Posttranslational modification, protein turnover, chaperones:Inorganic ion transport and metabolism:Pyrimidine metabolism:Porphyrin and chlorophyll metabolism:Metabolic pathways:Two-component system:Flagellar assembly:Homologous recombination:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:Function unknown:Signal transduction mechanisms:TIGR00056:sensory_box:small_GTP:aat:ncs2:upp:CPA3_mnhG_phaG:recC:YCCS:BioC:cobalto_cobN:flagell_FliJ:Intracellular trafficking, secretion, and vesicular transport:Cell envelope:Nucleotide Metabolism:Metabolism of Cofactors and Vitamins:Genetic Information Processing:Replication and Repair:Environmental Information Processing:Signal Transduction:Cellular Processes:Cell Motility:Global:Metabolism:Purines, pyrimidines, nucleosides, and nucleotides:Salvage of nucleosides and nucleotides:Regulatory functions:Small molecule interactions:DNA metabolism:DNA replication, recombination, and repair:Protein fate:Degradation of proteins, peptides, and glycopeptides:Transport and binding proteins:Cations and iron carrying compounds:Nucleosides, purines and pyrimidines:Hypothetical proteins:Conserved:Unknown function:General:Biosynthesis of cofactors, prosthetic groups, and carriers:Biotin:Heme, porphyrin, and cobalamin:Metabolism:Other:Information storage and processing:Cellular processes and signaling:Metabolism:Poorly characterized" 61 "RNA processing and modification:Energy production and conversion:Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II:Membrane protease subunits, stomatin/prohibitin homologs:Predicted amidohydrolase:RNA 3'-terminal phosphate cyclase:Adenylate kinase and related kinases:Transcriptional regulator:Signal transduction histidine kinase:Spermidine/putrescine-binding periplasmic protein:Predicted nucleoside-diphosphate-sugar epimerases:Methyl-accepting chemotaxis protein:Enoyl-CoA hydratase/carnithine racemase:3-hydroxyacyl-CoA dehydrogenase:Na+/H+-dicarboxylate symporters:Transcriptional regulator:Uncharacterized conserved protein:Transcriptional regulators:NADH:flavin oxidoreductases, Old Yellow Enzyme family:Uncharacterized conserved protein, contains double-stranded beta-helix domain:Acyl-CoA dehydrogenases:Uncharacterized protein, possibly involved in aromatic compounds catabolism:Adenosine deaminase:AraC-type DNA-binding domain-containing proteins:Sugar phosphate permease:Transposase and inactivated derivatives:Arabinose efflux permease:Trans-aconitate methyltransferase:Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain:Amino acid transport and metabolism:Nucleotide transport and metabolism:Carbohydrate transport and metabolism:Lipid transport and metabolism:Transcription:Replication, recombination and repair:Cell wall/membrane/envelope biogenesis:Cell motility:Posttranslational modification, protein turnover, chaperones:Fatty acid metabolism:Valine leucine and isoleucine degradation:Geraniol degradation:Lysine degradation:Arginine and proline metabolism:Benzoate degradation:Tryptophan metabolism:beta-Alanine metabolism:Aminobenzoate degradation:Propanoate metabolism:Butanoate metabolism:Limonene and pinene degradation:Caprolactam degradation:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:Two-component system:Bacterial chemotaxis:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:Function unknown:Signal transduction mechanisms:sensory_box:unchar_dom_1:efflux_Bcr_CflA:agmatine_aguB:RNA_3prim_cycl:Cellular processes and signaling:Information storage and processing:RNA processing:Transcription:Small molecule interactions:Regulatory functions:Polyamine biosynthesis:Central intermediary metabolism:Metabolism:Metabolism:Global:Cell Motility:Cellular Processes:Signal Transduction:Environmental Information Processing:Xenobiotics Biodegradation and Metabolism:Metabolism of Terpenoids and Polyketides:Metabolism of Other Amino Acids:Amino Acid Metabolism:Lipid Metabolism:Poorly characterized:Carbohydrate Metabolism:Metabolism" 62 "Energy production and conversion:Glutamate synthase domain 2:Thymidylate kinase:Dethiobiotin synthetase:2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase:Molecular chaperone, HSP90 family:NADPH-dependent glutamate synthase beta chain and related oxidoreductases:Transcriptional regulator:Uncharacterized membrane protein (homolog of Drosophila rhomboid):Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains):ABC-type amino acid transport/signal transduction systems, periplasmic component/domain:L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases:Transcriptional regulator:Glutamine synthetase adenylyltransferase:Beta-glucosidase-related glycosidases:DNA-binding protein, stimulates sugar fermentation:Lauroyl/myristoyl acyltransferase:Exonuclease VII, large subunit:Outer membrane receptor proteins, mostly Fe transport:Transcriptional regulators:NADH:flavin oxidoreductases, Old Yellow Enzyme family:Pyrimidine reductase, riboflavin biosynthesis:FOG: GGDEF domain:Membrane-bound lytic murein transglycosylase:Na+-transporting NADH:ubiquinone oxidoreductase, subunit NqrF:Peptidylarginine deiminase and related enzymes:Predicted membrane protein:Predicted acetyltransferase:Large exoproteins involved in heme utilization or adhesion:Selenocysteine-specific translation elongation factor:Uncharacterized protein conserved in bacteria:Site-specific recombinase XerC:Predicted secreted protein:Amino acid transport and metabolism:Nucleotide transport and metabolism:Carbohydrate transport and metabolism:Coenzyme transport and metabolism:Lipid transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:Replication, recombination and repair:Cell wall/membrane/envelope biogenesis:Posttranslational modification, protein turnover, chaperones:Inorganic ion transport and metabolism:Pyrimidine metabolism:Alanine aspartate and glutamate metabolism:Arginine and proline metabolism:Cyanoamino acid metabolism:Starch and sucrose metabolism:Lipopolysaccharide biosynthesis:Pyruvate metabolism:Riboflavin metabolism:Biotin metabolism:Terpenoid backbone biosynthesis:Nitrogen metabolism:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:Mismatch repair:General function prediction only:Function unknown:Signal transduction mechanisms:DTMP_kinase:ispF:ribD_Cterm:sfsA:small_GTP:xseA:GGDEF:bioD:2A0125:gltD_gamma_fam:YD_repeat_2x:fil_hemag_20aa:recomb_XerC:agmatine_aguA:Intracellular trafficking, secretion, and vesicular transport:Degradation of DNA:DNA metabolism:Other:Regulatory functions:Nucleotide and nucleoside interconversions:Purines, pyrimidines, nucleosides, and nucleotides:Polyamine biosynthesis:Central intermediary metabolism:Metabolism:Metabolism:Global:Replication and Repair:Genetic Information Processing:Metabolism of Terpenoids and Polyketides:Metabolism of Cofactors and Vitamins:Glycan Biosynthesis and Metabolism:Metabolism of Other Amino Acids:Amino Acid Metabolism:Nucleotide Metabolism:Energy Metabolism:Poorly characterized:Carbohydrate Metabolism:Metabolism:Cellular processes and signaling:Information storage and processing:Other:Signal transduction:Biotin:Other:Biosynthesis of cofactors, prosthetic groups, and carriers:General:Unknown function:Adaptations to atypical conditions:Cellular processes:DNA replication, recombination, and repair" 63 "Energy production and conversion:N-formylmethionyl-tRNA deformylase:GMP synthase - Glutamine amidotransferase domain:Universal stress protein UspA and related nucleotide-binding proteins:Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs:Acylphosphatases:Amidases related to nicotinamidase:Uncharacterized protein SCO1/SenC/PrrC, involved in biogenesis of respiratory and photosynthetic systems:3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases:Molybdenum cofactor biosynthesis enzyme:Alkylated DNA repair protein:Predicted NAD/FAD-dependent oxidoreductase:Ketosteroid isomerase-related protein:Inhibitor of the KinA pathway to sporulation, predicted exonuclease:Pyrroloquinoline quinone (Coenzyme PQQ) biosynthesis protein C:Amino acid transport and metabolism:Nucleotide transport and metabolism:Coenzyme transport and metabolism:Lipid transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:Replication, recombination and repair:Valine leucine and isoleucine degradation:Pyruvate metabolism:Aminobenzoate degradation:Metabolic pathways:Microbial metabolism in diverse environments:Sulfur relay system:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:Signal transduction mechanisms:moaA:Genetic Information Processing:Xenobiotics Biodegradation and Metabolism:Amino Acid Metabolism:Poorly characterized:Carbohydrate Metabolism:Metabolism:Metabolism:Cellular processes and signaling:Information storage and processing:Molybdopterin:Biosynthesis of cofactors, prosthetic groups, and carriers:Metabolism:Global:Folding Sorting and Degradation" 64 "Energy production and conversion:Translation elongation factors (GTPases):Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily):Cytochrome bd-type quinol oxidase, subunit 1:Cytochrome bd-type quinol oxidase, subunit 2:Transglutaminase-like enzymes, putative cysteine proteases:Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL homologs:Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS/CutS homologs:Poly(3-hydroxyalkanoate) synthetase:Predicted proteasome-type protease:Amino acid transport and metabolism:Lipid transport and metabolism:Translation, ribosomal structure and biogenesis:Posttranslational modification, protein turnover, chaperones:Oxidative phosphorylation:Butanoate metabolism:Metabolic pathways:General function prediction only:cydB:small_GTP:PHA_synth_II:PHA_depoly_arom:Information storage and processing:Carbohydrate Metabolism:Energy Metabolism:Global:Metabolism:Energy metabolism:Electron transport:Other:Fatty acid and phospholipid metabolism:Biosynthesis:Unknown function:General:Metabolism:Cellular processes and signaling:Metabolism:Poorly characterized" 65 "Single-stranded DNA-specific exonuclease:Predicted Fe-S-cluster oxidoreductase:Outer membrane protein:Predicted permeases:3-dehydroquinate dehydratase II:Branched-chain amino acid permeases:ABC-type multidrug transport system, ATPase and permease components:Uncharacterized protein conserved in bacteria:Multidrug resistance efflux pump:Predicted permease:Predicted flavoproteins:Predicted membrane protein:3-methyladenine DNA glycosylase:Predicted membrane protein:Aminoglycoside phosphotransferase:Uncharacterized conserved protein:Amino acid transport and metabolism:Translation, ribosomal structure and biogenesis:Replication, recombination and repair:Cell wall/membrane/envelope biogenesis:Phenylalanine tyrosine and tryptophan biosynthesis:Metabolic pathways:Biosynthesis of secondary metabolites:ABC transporters:Base excision repair:Mismatch repair:Homologous recombination:General function prediction only:Function unknown:TIGR00046:TIGR00275:tag:recJ:livcs:aroQ:RND_mfp:Defense mechanisms:Transport and binding proteins:tRNA and rRNA base modification:Protein synthesis:DNA replication, recombination, and repair:DNA metabolism:Metabolism:Global:Membrane Transport:Environmental Information Processing:Metabolism:Replication and Repair:Genetic Information Processing:Unknown substrate:Amino Acid Metabolism:Amino acids, peptides and amines:Unknown function:Enzymes of unknown specificity:Amino acid biosynthesis:Aromatic amino acid family:Information storage and processing:Cellular processes and signaling:Metabolism:Poorly characterized" 66 "Serine/threonine protein kinase:Serine/threonine protein phosphatase:ABC-type antimicrobial peptide transport system, ATPase component:Uncharacterized conserved protein:Large extracellular alpha-helical protein:Rhs family protein:Uncharacterized protein conserved in bacteria:Uncharacterized protein conserved in bacteria:Uncharacterized conserved protein, contains FHA domain:Uncharacterized protein conserved in bacteria:Uncharacterized protein conserved in bacteria:Uncharacterized protein conserved in bacteria:ABC-type transport system, involved in lipoprotein release, permease component:Uncharacterized protein conserved in bacteria:Uncharacterized protein conserved in bacteria:Predicted membrane protein:Predicted secreted protein:Transcription:Replication, recombination and repair:Cell wall/membrane/envelope biogenesis:Bacterial secretion system:General function prediction only:Function unknown:Signal transduction mechanisms:YD_repeat_2x:IV_VI_DotU:VI_chp_3:VI_chp_4:VI_FHA:VI_minor_4:Defense mechanisms:Membrane Transport:Environmental Information Processing:Poorly characterized:Cellular processes and signaling:Information storage and processing:Pathogenesis:Cellular processes" 67 "Predicted S-adenosylmethionine-dependent methyltransferase involved in cell envelope biogenesis:Dihydropteroate synthase and related enzymes:UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N-acetylglucosamine-1-phosphate transferase:UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase:Cell division protein FtsI/penicillin-binding protein 2:UDP-N-acetylmuramyl tripeptide synthase:UDP-N-acetylmuramyl pentapeptide synthase:UDP-N-acetylmuramoylalanine-D-glutamate ligase:Bacterial cell division membrane protein:UDP-N-acetylmuramate-alanine ligase:Actin-like ATPase involved in cell division:Phosphomannomutase:D-alanine-D-alanine ligase and related ATP-grasp enzymes:Cell division septal protein:Uncharacterized protein conserved in bacteria:Uncharacterized protein conserved in bacteria:Cell division protein:Cell cycle control, cell division, chromosome partitioning:Carbohydrate transport and metabolism:Coenzyme transport and metabolism:Cell wall/membrane/envelope biogenesis:Lysine biosynthesis:D-Glutamine and D-glutamate metabolism:D-Alanine metabolism:Amino sugar and nucleotide sugar metabolism:Peptidoglycan biosynthesis:Folate biosynthesis:Metabolic pathways:Function unknown:TIGR00006:TIGR00242:mraY:murC:murE:murD:murG:murF:ftsA:D_ala_D_alaTIGR:glmM:DHPS:ftsL_broad:ftsW:Metabolism:Carbohydrate Metabolism:Amino Acid Metabolism:Metabolism of Other Amino Acids:Glycan Biosynthesis and Metabolism:Metabolism of Cofactors and Vitamins:Global:Metabolism:Central intermediary metabolism:Amino sugars:Cellular processes:Cell division:Unknown function:General:Biosynthesis of cofactors, prosthetic groups, and carriers:Folic acid:Cell envelope:Biosynthesis and degradation of murein sacculus and peptidoglycan:Cellular processes and signaling:Metabolism:Poorly characterized" 68 "Energy production and conversion:Short-chain dehydrogenases of various substrate specificities:3-oxoacyl-(acyl-carrier-protein) synthase:Amino acid transporters:Transcriptional regulator:Predicted oxidoreductases (related to aryl-alcohol dehydrogenases):Membrane proteins related to metalloendopeptidases:Cell wall-associated hydrolases (invasion-associated proteins):Methyl-accepting chemotaxis protein:NAD-dependent protein deacetylases, SIR2 family:Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases):ABC-type multidrug transport system, ATPase component:DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog:Predicted transcriptional regulators:N-Dimethylarginine dimethylaminohydrolase:Predicted membrane protein:Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains:Uncharacterized vancomycin resistance protein:Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains:Predicted O-methyltransferase:Amino acid transport and metabolism:Lipid transport and metabolism:Transcription:Cell wall/membrane/envelope biogenesis:Cell motility:Fatty acid biosynthesis:Histidine metabolism:Tyrosine metabolism:Selenocompound metabolism:Amino sugar and nucleotide sugar metabolism:Polycyclic aromatic hydrocarbon degradation:Metabolic pathways:Microbial metabolism in diverse environments:ABC transporters:RNA polymerase:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:Function unknown:Signal transduction mechanisms:2A0302:sigma70-ECF:fabF:Defense mechanisms:Metabolism:Amino acids, peptides and amines:Transport and binding proteins:Biosynthesis:Fatty acid and phospholipid metabolism:Poorly characterized:Metabolism:Global:Membrane Transport:Environmental Information Processing:Metabolism:Transcription:Genetic Information Processing:Xenobiotics Biodegradation and Metabolism:Metabolism of Other Amino Acids:Amino Acid Metabolism:Lipid Metabolism:Information storage and processing:Carbohydrate Metabolism:Cellular processes and signaling" 69 "Aspartyl-tRNA synthetase:Uncharacterized conserved protein:Aspartokinases:Ribosomal protein S1:Holliday junction resolvasome, DNA-binding subunit:Biopolymer transport proteins:Holliday junction resolvasome, endonuclease subunit:Predicted thioesterase:Organic solvent tolerance protein OstA:Uncharacterized protein conserved in bacteria:Holliday junction resolvasome, helicase subunit:Uncharacterized protein conserved in archaea:Amino acid transport and metabolism:Translation, ribosomal structure and biogenesis:Replication, recombination and repair:Cell wall/membrane/envelope biogenesis:Posttranslational modification, protein turnover, chaperones:Ubiquinone and other terpenoid-quinone biosynthesis:Glycine serine and threonine metabolism:Cysteine and methionine metabolism:Lysine biosynthesis:Benzoate degradation:Aminoacyl-tRNA biosynthesis:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:Ribosome:Homologous recombination:General function prediction only:Function unknown:TIGR00051:ruvA:ruvC:aspS_bact:ruvB:asp_kin_monofn:rpsA:TIGR01033:tonB_Cterm:tol_pal_ybgF:tolQ:Intracellular trafficking, secretion, and vesicular transport:General:Amino Acid Metabolism:Metabolism of Cofactors and Vitamins:Xenobiotics Biodegradation and Metabolism:Genetic Information Processing:Translation:Replication and Repair:Global:Metabolism:Regulatory functions:DNA interactions:DNA metabolism:DNA replication, recombination, and repair:Protein synthesis:tRNA aminoacylation:Ribosomal proteins: synthesis and modification:Transport and binding proteins:Cations and iron carrying compounds:Cellular processes:Pathogenesis:Unknown function:Metabolism:Amino acid biosynthesis:Aspartate family:Information storage and processing:Cellular processes and signaling:Metabolism:Poorly characterized" 70 "NTP pyrophosphohydrolases including oxidative damage repair enzymes:Uncharacterized membrane-associated protein:Glutathione S-transferase:cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases:Predicted permeases:Bacterial nucleoid DNA-binding protein:Predicted thioesterase:ATPases involved in chromosome partitioning:Uncharacterized protein (competence- and mitomycin-induced):Uncharacterized conserved protein:Ketopantoate reductase:Peroxiredoxin:Adenosine deaminase:Lysophospholipase L1 and related esterases:Uncharacterized protein conserved in bacteria:Uncharacterized conserved protein:Cell cycle control, cell division, chromosome partitioning:Amino acid transport and metabolism:Nucleotide transport and metabolism:Coenzyme transport and metabolism:Replication, recombination and repair:Posttranslational modification, protein turnover, chaperones:Glutathione metabolism:Pantothenate and CoA biosynthesis:Biosynthesis of unsaturated fatty acids:Metabolic pathways:Biosynthesis of secondary metabolites:RNA degradation:General function prediction only:Function unknown:Signal transduction mechanisms:TIGR00051:cinA_cterm:apbA_panE:hip:TIGR02096:TIGR02448:TMPT_Se_Te:Cellular processes and signaling:Lipid Metabolism:Metabolism of Other Amino Acids:Metabolism of Cofactors and Vitamins:Genetic Information Processing:Folding Sorting and Degradation:Global:Metabolism:DNA metabolism:DNA replication, recombination, and repair:Unknown function:General:Biosynthesis of cofactors, prosthetic groups, and carriers:Pantothenate and coenzyme A:Information storage and processing:Metabolism:Metabolism:Poorly characterized" 71 "Energy production and conversion:ABC-type branched-chain amino acid transport systems, periplasmic component:ABC-type multidrug transport system, ATPase component:Putative threonine efflux protein:Predicted membrane protein:Multidrug resistance efflux pump:Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases:AraC-type DNA-binding domain-containing proteins:Sugar phosphate permease:P pilus assembly protein, porin PapC:ABC-type uncharacterized transport system involved in gliding motility, auxiliary component:Amino acid transport and metabolism:Carbohydrate transport and metabolism:Transcription:Cell motility:ABC transporters:Function unknown:RND_mfp:urea_ABC_UrtA:LLM_DMSO2_sfnG:Intracellular trafficking, secretion, and vesicular transport:Defense mechanisms:Environmental Information Processing:Poorly characterized:Metabolism:Cellular processes and signaling:Information storage and processing:Amino acids, peptides and amines:Unknown substrate:Transport and binding proteins:Sulfur metabolism:Central intermediary metabolism:Membrane Transport" 72 "Acetylglutamate semialdehyde dehydrogenase:Predicted phosphoesterase:Phosphopantetheine adenylyltransferase:CMP-2-keto-3-deoxyoctulosonic acid synthetase:Transcriptional regulator:Flagellar motor protein:Beta-glucosidase-related glycosidases:Integral membrane protein CcmA involved in cell shape determination:Transcriptional regulators:Serine phosphatase RsbU, regulator of sigma subunit:Uncharacterized conserved protein:Predicted endonuclease containing a URI domain:Uncharacterized protein conserved in bacteria:Uncharacterized protein conserved in bacteria:Uncharacterized membrane protein required for alginate biosynthesis:Amino acid transport and metabolism:Carbohydrate transport and metabolism:Coenzyme transport and metabolism:Transcription:Replication, recombination and repair:Cell wall/membrane/envelope biogenesis:Cell motility:Lysine biosynthesis:Arginine and proline metabolism:Amino sugar and nucleotide sugar metabolism:Lipopolysaccharide biosynthesis:Pantothenate and CoA biosynthesis:Metabolic pathways:Biosynthesis of secondary metabolites:General function prediction only:Function unknown:Signal transduction mechanisms:yfcE:cyt_tran_rel:kdsB:argC:Metabolism:Carbohydrate Metabolism:Amino Acid Metabolism:Glycan Biosynthesis and Metabolism:Metabolism of Cofactors and Vitamins:Global:Metabolism:Unknown function:Enzymes of unknown specificity:Amino acid biosynthesis:Glutamate family:Cell envelope:Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides:Information storage and processing:Cellular processes and signaling:Metabolism:Poorly characterized" 73 "Non-ribosomal peptide synthetase modules and related proteins:Probable taurine catabolism dioxygenase:Hemolysin-coregulated protein (uncharacterized):Uncharacterized protein conserved in bacteria:Uncharacterized protein conserved in bacteria:Uncharacterized protein conserved in bacteria:Uncharacterized protein conserved in bacteria:Uncharacterized protein conserved in bacteria:Uncharacterized protein conserved in bacteria:Uncharacterized protein conserved in bacteria:Uncharacterized protein conserved in bacteria:Bacterial secretion system:Secondary metabolites biosynthesis, transport and catabolism:Function unknown:fkbM_fam:vgr_GE:AA-adenyl-dom:VI_chp_1:IV_VI_DotU:VI_chp_4:VI_chp_2:VI_zyme:VI_chp_5:VI_chp_8:Metabolism:Membrane Transport:Cellular processes:Pathogenesis:Environmental Information Processing:Poorly characterized" 74 "Energy production and conversion:Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase:Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases:Putative translation initiation inhibitor, yjgF family:Membrane protease subunits, stomatin/prohibitin homologs:ABC-type branched-chain amino acid transport systems, ATPase component:Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily):Glycine/D-amino acid oxidases (deaminating):Spermidine/putrescine-binding periplasmic protein:ABC-type amino acid transport/signal transduction systems, periplasmic component/domain:Methyl-accepting chemotaxis protein:Membrane-fusion protein:Membrane-bound serine protease (ClpP class):Transcriptional regulator:Uncharacterized ABC-type transport system, periplasmic component/surface lipoprotein:Cytochrome c peroxidase:Acyl-CoA dehydrogenases:Allophanate hydrolase subunit 2:Predicted ornithine cyclodeaminase, mu-crystallin homolog:Uncharacterized protein involved in response to NO:Isopenicillin N synthase and related dioxygenases:ABC-type branched-chain amino acid transport system, permease component:Predicted lipoprotein involved in nitrous oxide reduction:Amino acid transport and metabolism:Carbohydrate transport and metabolism:Lipid transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:Cell wall/membrane/envelope biogenesis:Cell motility:Posttranslational modification, protein turnover, chaperones:Inorganic ion transport and metabolism:Geraniol degradation:Arginine and proline metabolism:Histidine metabolism:Tyrosine metabolism:Phenylalanine metabolism:Phenylalanine tyrosine and tryptophan biosynthesis:Novobiocin biosynthesis:Naphthalene degradation:Nitrogen metabolism:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:ABC transporters:General function prediction only:Signal transduction mechanisms:urea_amlyse_rel:Poorly characterized:Metabolism:Cellular processes and signaling:Information storage and processing:General:Unknown function:Metabolism:Global:Membrane Transport:Environmental Information Processing:Xenobiotics Biodegradation and Metabolism:Biosynthesis of Other Secondary Metabolites:Metabolism of Terpenoids and Polyketides:Amino Acid Metabolism:Metabolism:Energy Metabolism" 75 "Phenylalanyl-tRNA synthetase beta subunit:Signal transduction histidine kinase:Uncharacterized protein conserved in bacteria:Sec-independent protein secretion pathway component TatC:Periplasmic component of the Tol biopolymer transport system:Biopolymer transport protein:DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog:Uncharacterized protein conserved in bacteria:Sec-independent protein secretion pathway components:Phosphotransferase system, HPr-related proteins:Outer membrane protein:Outer membrane lipoprotein-sorting protein:Uncharacterized protein conserved in bacteria:Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain:Carbohydrate transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:Cell wall/membrane/envelope biogenesis:Aminoacyl-tRNA biosynthesis:Two-component system:RNA polymerase:Protein export:Bacterial secretion system:Function unknown:Signal transduction mechanisms:DNA_YbaB_EbfC:pheT_bact:lolA:tatC:PTS_HPr_family:tatB:rpoN_sigma:propeller_TolB:tolR:Intracellular trafficking, secretion, and vesicular transport:Poorly characterized:Transcription:Translation:Folding Sorting and Degradation:Environmental Information Processing:Membrane Transport:Signal Transduction:Transcription:Transcription factors:Protein synthesis:tRNA aminoacylation:Protein fate:Protein and peptide secretion and trafficking:Cellular processes:Pathogenesis:Unknown function:General:Signal transduction:PTS:Information storage and processing:Cellular processes and signaling:Metabolism:Genetic Information Processing" 76 "1-acyl-sn-glycerol-3-phosphate acyltransferase:Lysophospholipase:Uncharacterized protein conserved in bacteria:Large extracellular alpha-helical protein:Predicted membrane protein:Rhs family protein:Uncharacterized protein conserved in bacteria:Uncharacterized protein conserved in bacteria:Predicted CDP-diglyceride synthetase/phosphatidate cytidylyltransferase:Uncharacterized protein conserved in bacteria:Uncharacterized protein conserved in bacteria:Lipid transport and metabolism:Cell wall/membrane/envelope biogenesis:Glycerophospholipid metabolism:Metabolic pathways:General function prediction only:Function unknown:YD_repeat_2x:Poorly characterized:Metabolism:Cellular processes and signaling:Metabolism:Global:Lipid Metabolism:Metabolism" 77 "Energy production and conversion:Riboflavin synthase beta-chain:Riboflavin synthase alpha chain:(acyl-carrier-protein) S-malonyltransferase:Predicted tRNA(5-methylaminomethyl-2-thiouridylate) methyltransferase, contains the PP-loop ATPase domain:Multimeric flavodoxin WrbA:Transcription termination factor:Transcription elongation factor:Acetyl-CoA carboxylase alpha subunit:Arsenate reductase and related proteins, glutaredoxin family:Na+-transporting NADH:ubiquinone oxidoreductase, subunit NqrA:Cytochrome c5:ATP phosphoribosyltransferase involved in histidine biosynthesis:Amino acid transport and metabolism:Coenzyme transport and metabolism:Lipid transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:Inorganic ion transport and metabolism:Fatty acid biosynthesis:Histidine metabolism:Pyruvate metabolism:Propanoate metabolism:Carbon fixation pathways in prokaryotes:Riboflavin metabolism:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:Sulfur relay system:General function prediction only:arsC:lumazine-synth:fabD:ribE:trmU:hisZ_biosyn_reg:accA:flav_wrbA:nqrA:nusB:Amino acid biosynthesis:Carbohydrate Metabolism:Energy Metabolism:Lipid Metabolism:Amino Acid Metabolism:Metabolism of Cofactors and Vitamins:Genetic Information Processing:Folding Sorting and Degradation:Global:Metabolism:Energy metabolism:Electron transport:Fatty acid and phospholipid metabolism:Biosynthesis:Transcription:Transcription factors:Protein synthesis:tRNA and rRNA base modification:Transport and binding proteins:Cations and iron carrying compounds:Cellular processes:Detoxification:Metabolism:Histidine family:Biosynthesis of cofactors, prosthetic groups, and carriers:Riboflavin, FMN, and FAD:Information storage and processing:Metabolism:Poorly characterized" 78 "Diaminopimelate decarboxylase:Adenosylmethionine-8-amino-7-oxononanoate aminotransferase:3-dehydroquinate synthetase:Kef-type K+ transport systems, membrane components:Small-conductance mechanosensitive channel:Prolipoprotein diacylglyceryltransferase:DNA polymerase III, epsilon subunit and related 3'-5' exonucleases:Arginine decarboxylase (spermidine biosynthesis):Phosphatidylserine synthase:Monoamine oxidase:Transcriptional regulator:Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily:Predicted signal transduction protein:Predicted membrane-associated, metal-dependent hydrolase:Protein related to penicillin acylase:Uncharacterized conserved protein:Signal transduction histidine kinase, nitrogen specific:Amino acid transport and metabolism:Coenzyme transport and metabolism:Lipid transport and metabolism:Transcription:Replication, recombination and repair:Cell wall/membrane/envelope biogenesis:Inorganic ion transport and metabolism:Purine metabolism:Pyrimidine metabolism:Glycine serine and threonine metabolism:Arginine and proline metabolism:Histidine metabolism:Tyrosine metabolism:Phenylalanine metabolism:Tryptophan metabolism:Phenylalanine tyrosine and tryptophan biosynthesis:Glutathione metabolism:Glycerophospholipid metabolism:Biotin metabolism:Metabolic pathways:Biosynthesis of secondary metabolites:Two-component system:DNA replication:Mismatch repair:Homologous recombination:General function prediction only:Function unknown:Signal transduction mechanisms:pssA:bioA:lgt:dnaq:2a37:speA:aroB:Cellular processes and signaling:Metabolism:Poorly characterized:Fatty acid and phospholipid metabolism:Polyamine biosynthesis:Central intermediary metabolism:Metabolism:Global:Signal Transduction:Environmental Information Processing:Metabolism:Replication and Repair:Genetic Information Processing:Metabolism of Cofactors and Vitamins:Metabolism of Other Amino Acids:Amino Acid Metabolism:Nucleotide Metabolism:Biosynthesis:Lipid Metabolism:DNA metabolism:Degradation of DNA:Protein fate:Protein modification and repair:Transport and binding proteins:Cations and iron carrying compounds:Amino acid biosynthesis:Aromatic amino acid family:Biosynthesis of cofactors, prosthetic groups, and carriers:Biotin:Information storage and processing" 79 "Energy production and conversion:Carbonic anhydrase:Short-chain dehydrogenases of various substrate specificities:Glutathione peroxidase:Transcriptional regulator:NADPH:quinone reductase and related Zn-dependent oxidoreductases:ABC-type amino acid transport/signal transduction systems, periplasmic component/domain:Methyl-accepting chemotaxis protein:Enoyl-CoA hydratase/carnithine racemase:Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases):Transcriptional regulator:Cyanate lyase:Transcriptional regulators:NADH:flavin oxidoreductases, Old Yellow Enzyme family:Predicted flavoprotein involved in K+ transport:FOG: GGDEF domain:Acetyl/propionyl-CoA carboxylase, alpha subunit:Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta):Amino acid transport and metabolism:Lipid transport and metabolism:Transcription:Cell motility:Posttranslational modification, protein turnover, chaperones:Inorganic ion transport and metabolism:Geraniol degradation:Glutathione metabolism:Arachidonic acid metabolism:Nitrotoluene degradation:Nitrogen metabolism:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:Two-component system:Bacterial chemotaxis:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:Signal transduction mechanisms:GGDEF:cynS:3A0103s03R:Poorly characterized:Metabolism:Cellular processes and signaling:Information storage and processing:Other:Signal transduction:Detoxification:Cellular processes:Amino acids, peptides and amines:Transport and binding proteins:Metabolism:Metabolism:Global:Cell Motility:Cellular Processes:Signal Transduction:Environmental Information Processing:Xenobiotics Biodegradation and Metabolism:Metabolism of Terpenoids and Polyketides:Metabolism of Other Amino Acids:Lipid Metabolism:Energy Metabolism" 80 "Energy production and conversion:Cysteine synthase:Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2:Amino acid transporters:ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components:Flavodoxin reductases (ferredoxin-NADPH reductases) family 1:Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases):Serine acetyltransferase:ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component:Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs:Predicted metal-dependent protease of the PAD1/JAB1 superfamily:Transcriptional regulator:Predicted dinucleotide-utilizing enzyme:Lysophospholipase:Predicted metal-dependent hydrolases related to alanyl-tRNA synthetase HxxxH domain:Phenylpropionate dioxygenase and related ring-hydroxylating dioxygenases, large terminal subunit:Tfp pilus assembly protein FimT:Amino acid transport and metabolism:Coenzyme transport and metabolism:Lipid transport and metabolism:Transcription:Cell motility:Inorganic ion transport and metabolism:Cysteine and methionine metabolism:Selenocompound metabolism:Nicotinate and nicotinamide metabolism:Sulfur metabolism:Metabolic pathways:Microbial metabolism in diverse environments:ABC transporters:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:IV_pilin_GFxxxE:Intracellular trafficking, secretion, and vesicular transport:Metabolism of Cofactors and Vitamins:Metabolism of Other Amino Acids:Amino Acid Metabolism:Poorly characterized:Energy Metabolism:Metabolism:Cellular processes and signaling:Information storage and processing:Protein and peptide secretion and trafficking:Protein fate:Metabolism:Metabolism:Global:Membrane Transport:Environmental Information Processing" 81 "Energy production and conversion:Uroporphyrinogen-III methylase:DNA mismatch repair enzyme (predicted ATPase):Anthranilate phosphoribosyltransferase:Chemotaxis protein histidine kinase and related kinases:2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases:Chemotaxis signal transduction protein:Methyl-accepting chemotaxis protein:N-acetylmuramoyl-L-alanine amidase:ABC-type transport system involved in resistance to organic solvents, ATPase component:ABC-type transport system involved in resistance to organic solvents, periplasmic component:DNA polymerase III, delta subunit:Uncharacterized conserved protein involved in intracellular sulfur reduction:Uncharacterized conserved protein involved in oxidation of intracellular sulfur:Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains:Dissimilatory sulfite reductase (desulfoviridin), gamma subunit:Uncharacterized protein involved in the oxidation of intracellular sulfur:ABC-type uncharacterized transport system, auxiliary component:Signal transduction histidine kinase regulating citrate/malate metabolism:Response regulator containing a CheY-like receiver domain and a GGDEF domain:Amino acid transport and metabolism:Coenzyme transport and metabolism:Replication, recombination and repair:Cell wall/membrane/envelope biogenesis:Cell motility:Inorganic ion transport and metabolism:Ubiquinone and other terpenoid-quinone biosynthesis:Purine metabolism:Pyrimidine metabolism:Porphyrin and chlorophyll metabolism:Metabolic pathways:Biosynthesis of secondary metabolites:Two-component system:DNA replication:Mismatch repair:Homologous recombination:Sulfur relay system:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:Signal transduction mechanisms:GGDEF:mutl:holA:cobA_cysG_Cterm:UbiH:sulf_tusC_dsrF:sulf_tusB_dsrH:sulf_tusD_dsrE:dsrC_tusE_dsvC:Cellular processes and signaling:Information storage and processing:Other:Signal transduction:Menaquinone and ubiquinone:Heme, porphyrin, and cobalamin:Biosynthesis of cofactors, prosthetic groups, and carriers:tRNA and rRNA base modification:Protein synthesis:DNA replication, recombination, and repair:DNA metabolism:Metabolism:Metabolism:Global:Signal Transduction:Environmental Information Processing:Replication and Repair:Folding Sorting and Degradation:Genetic Information Processing:Metabolism of Cofactors and Vitamins:Poorly characterized:Nucleotide Metabolism:Metabolism" 82 "Energy production and conversion:Dephospho-CoA kinase:FAD/FMN-containing dehydrogenases:NADH:ubiquinone oxidoreductase 20 kD subunit and related Fe-S oxidoreductases:Superfamily II DNA and RNA helicases:Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter, MnhD subunit:NADH:ubiquinone oxidoreductase subunit 3 (chain A):Multisubunit Na+/H+ antiporter, MnhC subunit:NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit:Choline-glycine betaine transporter:L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases:Transglutaminase-like enzymes, putative cysteine proteases:Multisubunit Na+/H+ antiporter, MnhG subunit:Predicted transcriptional regulators:L-lactate permease:D-alanyl-D-alanine carboxypeptidase:Multisubunit Na+/H+ antiporter, MnhE subunit:Multisubunit Na+/H+ antiporter, MnhF subunit:Uncharacterized protein conserved in bacteria:Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain:Amino acid transport and metabolism:Coenzyme transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:Replication, recombination and repair:Cell wall/membrane/envelope biogenesis:Inorganic ion transport and metabolism:Oxidative phosphorylation:Pyruvate metabolism:Pantothenate and CoA biosynthesis:Metabolic pathways:RNA degradation:Function unknown:Signal transduction mechanisms:TIGR00152:parB_part:sensory_box:lctP:bcct:CPA3_mnhG_phaG:nuoB_fam:Cellular processes and signaling:Carbohydrate Metabolism:Energy Metabolism:Metabolism of Cofactors and Vitamins:Genetic Information Processing:Folding Sorting and Degradation:Global:Metabolism:Energy metabolism:Electron transport:Regulatory functions:Small molecule interactions:Transport and binding proteins:Carbohydrates, organic alcohols, and acids:Cations and iron carrying compounds:Other:Biosynthesis of cofactors, prosthetic groups, and carriers:Pantothenate and coenzyme A:Information storage and processing:Metabolism:Metabolism:Poorly characterized" 83 "Energy production and conversion:Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase:Sulfite reductase, beta subunit (hemoprotein):Cobalamin-5-phosphate synthase:Fructose-2,6-bisphosphatase:Putative GTPases (G3E family):ABC-type Fe3+-siderophore transport system, permease component:ABC-type Fe3+-hydroxamate transport system, periplasmic component:Nitroreductase:ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components:Cobalamin biosynthesis protein CobD/CbiB:Cobalamin biosynthesis protein CobN and related Mg-chelatases:Cobyric acid synthase:Outer membrane receptor proteins, mostly Fe transport:Cobyrinic acid a,c-diamide synthase:NaMN:DMB phosphoribosyltransferase:Cobalamin biosynthesis protein CbiG:Precorrin isomerase:Adenosyl cobinamide kinase/adenosyl cobinamide phosphate guanylyltransferase:ATP:corrinoid adenosyltransferase:Precorrin-2 methylase:Outer membrane cobalamin receptor protein:Amino acid transport and metabolism:Carbohydrate transport and metabolism:Coenzyme transport and metabolism:Inorganic ion transport and metabolism:Riboflavin metabolism:Porphyrin and chlorophyll metabolism:Metabolic pathways:ABC transporters:General function prediction only:cobQ:cobS:cobB:cobD:cobA:L_thr_O3P_dcar:cobJ_cbiH:cobI_cbiL:TonB-B12:TonB-siderophor:cobalto_cobN:CobG:CobW:BluB:cobT_DBIPRT:Heme, porphyrin, and cobalamin:Biosynthesis of cofactors, prosthetic groups, and carriers:Porins:Transport and binding proteins:Metabolism:Metabolism:Global:Membrane Transport:Environmental Information Processing:Poorly characterized:Metabolism of Cofactors and Vitamins:Metabolism" 84 "Phosphoserine phosphatase:Small-conductance mechanosensitive channel:Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases):ABC-type spermidine/putrescine transport system, permease component II:Imidazolonepropionase and related amidohydrolases:Transglutaminase-like enzymes, putative cysteine proteases:Uncharacterized proteins of the AP superfamily:ABC-type Fe3+ transport system, periplasmic component:ABC-type proline/glycine betaine transport systems, periplasmic components:Putative NADP-dependent oxidoreductases:Glucose/sorbosone dehydrogenases:Uncharacterized protein conserved in bacteria:Uncharacterized conserved protein:Regulator of polyketide synthase expression:Uncharacterized protein conserved in bacteria:N-formylglutamate amidohydrolase:Uncharacterized conserved protein:Uncharacterized protein conserved in bacteria:ABC-type spermidine/putrescine transport systems, ATPase components:ABC-type uncharacterized transport system, permease component:ABC-type proline/glycine betaine transport system, permease component:Uncharacterized protein conserved in bacteria:Amino acid transport and metabolism:Carbohydrate transport and metabolism:Lipid transport and metabolism:Cell wall/membrane/envelope biogenesis:Inorganic ion transport and metabolism:Histidine metabolism:Metabolic pathways:ABC transporters:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:Function unknown:Signal transduction mechanisms:hutI:HAD-SF-IB:hutG_amidohyd:Unknown function:Amino acids and amines:Energy metabolism:Metabolism:Global:Membrane Transport:Environmental Information Processing:Amino Acid Metabolism:Metabolism:Poorly characterized:Metabolism:Cellular processes and signaling:Enzymes of unknown specificity" 85 "NhaP-type Na+/H+ and K+/H+ antiporters:Cytosine deaminase and related metal-dependent hydrolases:Mg2+ and Co2+ transporters:Sulfate permease and related transporters (MFS superfamily):Mannose-1-phosphate guanylyltransferase:Predicted UDP-glucose 6-dehydrogenase:Predicted membrane protein involved in D-alanine export:Predicted acyltransferases:FOG: GGDEF domain:SH3 domain protein:Nucleotide transport and metabolism:Lipid transport and metabolism:Cell wall/membrane/envelope biogenesis:Inorganic ion transport and metabolism:Fructose and mannose metabolism:Purine metabolism:Amino sugar and nucleotide sugar metabolism:Metabolic pathways:Biosynthesis of secondary metabolites:Two-component system:General function prediction only:Signal transduction mechanisms:GGDEF:GMP_PMI:guan_deamin:NDP-sugDHase:para_beta_helix:Poorly characterized:Carbohydrate Metabolism:Nucleotide Metabolism:Environmental Information Processing:Signal Transduction:Global:Metabolism:Purines, pyrimidines, nucleosides, and nucleotides:Other:Signal transduction:Other:Cell envelope:Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides:Cellular processes and signaling:Metabolism:Metabolism" 86 "Energy production and conversion:Predicted sugar kinase:Mg-dependent DNase:Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase:Cytosine deaminase and related metal-dependent hydrolases:Adenine/guanine phosphoribosyltransferases and related PRPP-binding proteins:Phosphoserine phosphatase:Glycine/D-amino acid oxidases (deaminating):Predicted ATPase or kinase:Periplasmic protein TonB, links inner and outer membranes:Predicted endonuclease involved in recombination (possible Holliday junction resolvase in Mycoplasmas and B. subtilis):16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases:Lauroyl/myristoyl acyltransferase:Uncharacterized Fe-S protein:Putative transcriptional regulator:Uncharacterized protein conserved in bacteria:Uncharacterized protein conserved in bacteria:Aspartyl/asparaginyl beta-hydroxylase and related dioxygenases:Amino acid transport and metabolism:Nucleotide transport and metabolism:Carbohydrate transport and metabolism:Coenzyme transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:Replication, recombination and repair:Cell wall/membrane/envelope biogenesis:Posttranslational modification, protein turnover, chaperones:Purine metabolism:Lipopolysaccharide biosynthesis:Thiamine metabolism:Metabolic pathways:General function prediction only:Function unknown:TIGR00093:HI0065_YjeE:yjeF_cterm:RNAse_H_YqgF:TIGR00276:apt:tonB_Cterm:HAD-SF-IB:MnmC_Cterm:Cellular processes and signaling:Nucleotide Metabolism:Glycan Biosynthesis and Metabolism:Metabolism of Cofactors and Vitamins:Global:Metabolism:Energy metabolism:Electron transport:Purines, pyrimidines, nucleosides, and nucleotides:Salvage of nucleosides and nucleotides:Protein synthesis:tRNA and rRNA base modification:Transport and binding proteins:Cations and iron carrying compounds:Unknown function:Enzymes of unknown specificity:General:Information storage and processing:Metabolism:Metabolism:Poorly characterized" 87 "Formate-dependent phosphoribosylglycinamide formyltransferase (GAR transformylase):dGTP triphosphohydrolase:Uncharacterized NAD(FAD)-dependent dehydrogenases:Acetyltransferases:Zn-dependent hydrolases, including glyoxylases:Amino acid transporters:Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases:Helicase subunit of the DNA excision repair complex:Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily):ABC-type amino acid transport/signal transduction systems, periplasmic component/domain:NAD-dependent protein deacetylases, SIR2 family:Adenosine deaminase:HD-GYP domain:Isopenicillin N synthase and related dioxygenases:Uncharacterized protein conserved in bacteria:Uncharacterized protein conserved in bacteria:ABC-type proline/glycine betaine transport system, ATPase component:ABC-type proline/glycine betaine transport system, permease component:Uncharacterized protein conserved in bacteria:Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain:Amino acid transport and metabolism:Nucleotide transport and metabolism:Carbohydrate transport and metabolism:Transcription:Replication, recombination and repair:Purine metabolism:Benzoate degradation:Amino sugar and nucleotide sugar metabolism:One carbon pool by folate:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:ABC transporters:Nucleotide excision repair:General function prediction only:Function unknown:Signal transduction mechanisms:sensory_box:HDIG:uvrb:purT:dGTP_triPase:TIGR02231:QEGLA:protocat_pcaD:ABC_choXWV_ATP:ABC_choXWV_perm:Cellular processes and signaling:Information storage and processing:Amino acids, peptides and amines:Transport and binding proteins:DNA replication, recombination, and repair:DNA metabolism:Small molecule interactions:Regulatory functions:Purine ribonucleotide biosynthesis:Nucleotide and nucleoside interconversions:Purines, pyrimidines, nucleosides, and nucleotides:Other:Energy metabolism:Metabolism:Metabolism:Global:Membrane Transport:Environmental Information Processing:Replication and Repair:Genetic Information Processing:Xenobiotics Biodegradation and Metabolism:Metabolism of Cofactors and Vitamins:Nucleotide Metabolism:Poorly characterized:Carbohydrate Metabolism:Metabolism" 88 "Energy production and conversion:Short-chain dehydrogenases of various substrate specificities:Predicted amidohydrolase:Peroxiredoxin:Sugar kinases, ribokinase family:NADPH:quinone reductase and related Zn-dependent oxidoreductases:Glutathione S-transferase:Bacterial nucleoid DNA-binding protein:DNA-binding ferritin-like protein (oxidative damage protectant):Non-ribosomal peptide synthetase modules and related proteins:ABC-type sugar transport system, ATPase component:Ribose/xylose/arabinose/galactoside ABC-type transport systems, permease components:Transcriptional regulator:Transcriptional regulators:Uncharacterized proteins, homologs of lactam utilization protein B:Transcriptional regulators:ABC-type sugar transport system, periplasmic component:Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains:Uncharacterized enzyme of heme biosynthesis:Outer membrane lipoprotein:Uncharacterized protein conserved in bacteria:Carbohydrate transport and metabolism:Coenzyme transport and metabolism:Transcription:Replication, recombination and repair:Cell wall/membrane/envelope biogenesis:Posttranslational modification, protein turnover, chaperones:Inorganic ion transport and metabolism:Pentose phosphate pathway:Porphyrin and chlorophyll metabolism:Metabolic pathways:Biosynthesis of secondary metabolites:ABC transporters:Bacterial chemotaxis:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:Function unknown:Signal transduction mechanisms:himA:AA-adenyl-dom:D_ribokin_bact:oxido_YhdH:Cellular Processes:Membrane Transport:Environmental Information Processing:Metabolism of Cofactors and Vitamins:Poorly characterized:Carbohydrate Metabolism:Metabolism:Cellular processes and signaling:Information storage and processing:Enzymes of unknown specificity:Unknown function:DNA replication, recombination, and repair:DNA metabolism:Metabolism:Sugars:Energy metabolism:Metabolism:Global:Cell Motility" 89 "Signal transduction histidine kinase:Alkaline phosphatase:Type II secretory pathway, pseudopilin PulG:Predicted extracellular nuclease:Metal-dependent hydrolase involved in phosphonate metabolism:Uncharacterized enzyme of phosphonate metabolism:Uncharacterized enzyme of phosphonate metabolism:Uncharacterized enzyme of phosphonate metabolism:ABC-type phosphate/phosphonate transport system, ATPase component:ABC-type phosphate/phosphonate transport system, permease component:ABC-type phosphonate transport system, ATPase component:ABC-type phosphonate transport system, ATPase component:Type II secretory pathway, component PulJ:Cell motility:Inorganic ion transport and metabolism:Aminobenzoate degradation:Folate biosynthesis:Metabolic pathways:Microbial metabolism in diverse environments:ABC transporters:Two-component system:Bacterial secretion system:General function prediction only:Signal transduction mechanisms:PhnE:typeII_sec_gspH:ABC_phnC:phosphono_phnM:CP_lyasePhnK:CP_lyasePhnL:IV_pilin_GFxxxE:PhnH_redo:Intracellular trafficking, secretion, and vesicular transport:Cellular processes and signaling:Metabolism of Cofactors and Vitamins:Xenobiotics Biodegradation and Metabolism:Environmental Information Processing:Membrane Transport:Signal Transduction:Global:Metabolism:Central intermediary metabolism:Phosphorus compounds:Energy metabolism:Other:Protein fate:Protein and peptide secretion and trafficking:Transport and binding proteins:Anions:Cellular processes:Pathogenesis:Metabolism:Metabolism:Poorly characterized" 90 "Energy production and conversion:Phosphoribosylaminoimidazole carboxylase (NCAIR synthetase):Phosphoribosylcarboxyaminoimidazole (NCAIR) mutase:AICAR transformylase/IMP cyclohydrolase PurH (only IMP cyclohydrolase domain in Aful):Phosphoribosylamine-glycine ligase:Guanylate kinase:IMP dehydrogenase/GMP reductase:Superfamily II DNA/RNA helicases, SNF2 family:2-methylthioadenine synthetase:Lysyl-tRNA synthetase (class II):Predicted membrane GTPase involved in stress response:Phosphoenolpyruvate carboxykinase (ATP):Tartrate dehydratase alpha subunit/Fumarate hydratase class I, N-terminal domain:Transcriptional accessory protein:Peptide chain release factor RF-3:Nucleotide transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:Replication, recombination and repair:Glycolysis / Gluconeogenesis:Citrate cycle (TCA cycle):Purine metabolism:Pyruvate metabolism:One carbon pool by folate:Carbon fixation pathways in prokaryotes:Aminoacyl-tRNA biosynthesis:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:Signal transduction mechanisms:TIGR00089:pckA:small_GTP:purH:lysS_bact:ttdA_fumA_fumB:purD:purK:purE:IMP_dehydrog:guanyl_kin:General:Carbohydrate Metabolism:Energy Metabolism:Nucleotide Metabolism:Metabolism of Cofactors and Vitamins:Genetic Information Processing:Translation:Global:Metabolism:Energy metabolism:Glycolysis/gluconeogenesis:Purines, pyrimidines, nucleosides, and nucleotides:Nucleotide and nucleoside interconversions:Purine ribonucleotide biosynthesis:Protein synthesis:tRNA aminoacylation:Unknown function:Metabolism:Information storage and processing:Cellular processes and signaling:Metabolism" 91 "7-keto-8-aminopelargonate synthetase and related enzymes:Lactoylglutathione lyase and related lyases:Aspartate/tyrosine/aromatic aminotransferase:SAM-dependent methyltransferases:Biotin synthase and related enzymes:Superfamily II DNA and RNA helicases:Acetylglutamate kinase:Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily):Signal transduction histidine kinase:Phosphoglyceromutase:ABC-type amino acid transport/signal transduction systems, periplasmic component/domain:Phosphomannomutase:ABC-type antimicrobial peptide transport system, ATPase component:D-alanyl-D-alanine carboxypeptidase (penicillin-binding protein 4):FOG: GGDEF domain:Membrane glycosyltransferase:Uncharacterized protein conserved in bacteria:Membrane carboxypeptidase/penicillin-binding protein:Amino acid transport and metabolism:Carbohydrate transport and metabolism:Coenzyme transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:Replication, recombination and repair:Cell wall/membrane/envelope biogenesis:Glycolysis / Gluconeogenesis:Pentose phosphate pathway:Fructose and mannose metabolism:Galactose metabolism:Purine metabolism:Lysine biosynthesis:Arginine and proline metabolism:Starch and sucrose metabolism:Amino sugar and nucleotide sugar metabolism:Streptomycin biosynthesis:Peptidoglycan biosynthesis:Pyruvate metabolism:Methane metabolism:Biotin metabolism:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:ABC transporters:Two-component system:RNA degradation:Protein export:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:Function unknown:Signal transduction mechanisms:glyox_I:GGDEF:bioB:PBP4:argB:bioF:pgm_bpd_ind:BioC:PBP_1a_fam:LolD_lipo_ex:Defense mechanisms:Cell envelope:Carbohydrate Metabolism:Energy Metabolism:Nucleotide Metabolism:Amino Acid Metabolism:Glycan Biosynthesis and Metabolism:Metabolism of Cofactors and Vitamins:Biosynthesis of Other Secondary Metabolites:Genetic Information Processing:Folding Sorting and Degradation:Environmental Information Processing:Membrane Transport:Signal Transduction:Global:Metabolism:Energy metabolism:Glycolysis/gluconeogenesis:Other:Protein fate:Protein and peptide secretion and trafficking:Amino acid biosynthesis:Glutamate family:Biosynthesis of cofactors, prosthetic groups, and carriers:Biotin:Signal transduction:Other:Metabolism:Biosynthesis and degradation of murein sacculus and peptidoglycan:Information storage and processing:Cellular processes and signaling:Metabolism:Poorly characterized" 92 "Metal-dependent hydrolases of the beta-lactamase superfamily I:Putative threonine efflux protein:Predicted membrane protein:Long-chain fatty acid transport protein:Membrane transporters of cations and cationic drugs:Multiple antibiotic transporter:AraC-type DNA-binding domain-containing proteins:Putative NADPH-quinone reductase (modulator of drug activity B):Sugar phosphate permease:Arabinose efflux permease:Predicted SAM-dependent methyltransferase:Predicted protein-disulfide isomerase:ABC-type phosphate/phosphonate transport system, permease component:Predicted metal-dependent hydrolase:ABC-type histidine transport system, ATPase component:Amino acid transport and metabolism:Carbohydrate transport and metabolism:Lipid transport and metabolism:Transcription:Posttranslational modification, protein turnover, chaperones:Inorganic ion transport and metabolism:ABC transporters:General function prediction only:Function unknown:TIGR00427:efflux_EmrB:PhnP:Intracellular trafficking, secretion, and vesicular transport:Membrane Transport:Environmental Information Processing:Poorly characterized:Metabolism:Cellular processes and signaling:Information storage and processing:General:Unknown function:Other:Transport and binding proteins" 93 "Energy production and conversion:ABC-type nitrate/sulfonate/bicarbonate transport system, permease component:ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components:Periplasmic protein TonB, links inner and outer membranes:Biopolymer transport proteins:Biopolymer transport protein:ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component:Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain:Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases:Probable taurine catabolism dioxygenase:Molybdopterin-binding protein:ABC-type taurine transport system, periplasmic component:ABC-type taurine transport system, ATPase component:Coenzyme transport and metabolism:Transcription:Cell wall/membrane/envelope biogenesis:Inorganic ion transport and metabolism:Taurine and hypotaurine metabolism:ABC transporters:Secondary metabolites biosynthesis, transport and catabolism:Signal transduction mechanisms:Mop:tonB_Cterm:SsuA_fam:taurine_ABC_bnd:alk_sulf_monoox:Intracellular trafficking, secretion, and vesicular transport:Cations and iron carrying compounds:Metabolism of Other Amino Acids:Other:Information storage and processing:Cellular processes and signaling:Metabolism:Metabolism:Anions:Transport and binding proteins:Sulfur metabolism:Central intermediary metabolism:Membrane Transport:Environmental Information Processing" 94 "Aspartate oxidase:Predicted sugar kinase:Acetolactate synthase, small (regulatory) subunit:MoxR-like ATPases:Predicted endonuclease distantly related to archaeal Holliday junction resolvase:Periplasmic protease:Uncharacterized protein conserved in bacteria:Methionine synthase I, cobalamin-binding domain:DNA segregation ATPase FtsK/SpoIIIE and related proteins:ATPase related to the helicase subunit of the Holliday junction resolvase:DNA polymerase III, gamma/tau subunits:Tfp pilus assembly protein PilF:Uncharacterized protein conserved in bacteria:Uncharacterized protein conserved in bacteria:Cell cycle control, cell division, chromosome partitioning:Amino acid transport and metabolism:Carbohydrate transport and metabolism:Coenzyme transport and metabolism:Replication, recombination and repair:Cell wall/membrane/envelope biogenesis:Cell motility:Purine metabolism:Pyrimidine metabolism:Alanine aspartate and glutamate metabolism:Cysteine and methionine metabolism:Valine leucine and isoleucine biosynthesis:Butanoate metabolism:C5-Branched dibasic acid metabolism:One carbon pool by folate:Nicotinate and nicotinamide metabolism:Pantothenate and CoA biosynthesis:Metabolic pathways:Biosynthesis of secondary metabolites:DNA replication:Mismatch repair:Homologous recombination:General function prediction only:Function unknown:acolac_sm:prc:TIGR00252:nadB:metH:dnaX_nterm:type_IV_pilW:Intracellular trafficking, secretion, and vesicular transport:Cellular processes and signaling:Carbohydrate Metabolism:Nucleotide Metabolism:Amino Acid Metabolism:Metabolism of Cofactors and Vitamins:Genetic Information Processing:Replication and Repair:Global:Metabolism:DNA metabolism:DNA replication, recombination, and repair:Protein fate:Protein modification and repair:Hypothetical proteins:Conserved:Amino acid biosynthesis:Aspartate family:Pyruvate family:Biosynthesis of cofactors, prosthetic groups, and carriers:Pyridine nucleotides:Information storage and processing:Metabolism:Metabolism:Poorly characterized" 95 "Energy production and conversion:Cysteine synthase:Transaldolase:Peptide methionine sulfoxide reductase:Carbonic anhydrase:Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family:Periplasmic protease:Phosphatidylserine synthase:Uncharacterized protein SCO1/SenC/PrrC, involved in biogenesis of respiratory and photosynthetic systems:Outer membrane protein and related peptidoglycan-associated (lipo)proteins:Uncharacterized protein involved in an early stage of isoprenoid biosynthesis:Azurin:Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain:Amino acid transport and metabolism:Carbohydrate transport and metabolism:Lipid transport and metabolism:Cell wall/membrane/envelope biogenesis:Posttranslational modification, protein turnover, chaperones:Inorganic ion transport and metabolism:Pentose phosphate pathway:Cysteine and methionine metabolism:Selenocompound metabolism:Glycerophospholipid metabolism:Nitrogen metabolism:Sulfur metabolism:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:Signal transduction mechanisms:prc:sensory_box:msrA:talAB:cysKM:TIGR02448:azurin:Electron transport:Energy metabolism:Metabolism:Metabolism:Global:Metabolism of Other Amino Acids:Amino Acid Metabolism:Lipid Metabolism:Energy Metabolism:Pentose phosphate pathway:Carbohydrate Metabolism:Regulatory functions:Small molecule interactions:Protein fate:Protein modification and repair:Cellular processes:Adaptations to atypical conditions:Amino acid biosynthesis:Serine family:Cellular processes and signaling:Metabolism:Poorly characterized" 96 "Predicted metal-dependent protease of the PAD1/JAB1 superfamily:DnaK suppressor protein:Negative regulator of beta-lactamase expression:Predicted chitinase:Phage-related protein:Phage-related protein:Phage-related protein, tail component:Phage-related protein, tail component:General function prediction only:Function unknown:Signal transduction mechanisms:phage_tail_L:C4_traR_proteo:Defense mechanisms:Poorly characterized:Cellular processes and signaling:Prophage functions:Mobile and extrachromosomal element functions" 97 "Energy production and conversion:Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase]:Anaerobic dehydrogenases, typically selenocysteine-containing:Predicted membrane metal-binding protein:Predicted transcriptional regulators:Acyl-CoA synthetase (NDP forming):Beta-propeller domains of methanol dehydrogenase type:Predicted acyltransferases:Acyl-CoA dehydrogenases:FOG: HPt domain:Xanthine/uracil permeases:Putative NADPH-quinone reductase (modulator of drug activity B):Predicted ornithine cyclodeaminase, mu-crystallin homolog:Arabinose efflux permease:O-Methyltransferase involved in polyketide biosynthesis:Gluconolactonase:Predicted lactoylglutathione lyase:Amino acid transport and metabolism:Nucleotide transport and metabolism:Carbohydrate transport and metabolism:Coenzyme transport and metabolism:Lipid transport and metabolism:Transcription:Geraniol degradation:Arginine and proline metabolism:Naphthalene degradation:Aminoacyl-tRNA biosynthesis:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:Signal transduction mechanisms:ComEC_N-term:ncs2:adhes_NPXG:Xenobiotics Biodegradation and Metabolism:Metabolism of Terpenoids and Polyketides:Cellular processes and signaling:Amino Acid Metabolism:Metabolism:Poorly characterized:Metabolism:Information storage and processing:General:Unknown function:Nucleosides, purines and pyrimidines:Transport and binding proteins:Metabolism:Global:Translation:Genetic Information Processing" 98 "Energy production and conversion:Uncharacterized conserved protein:Molecular chaperone:Cytosine/adenosine deaminases:Ferredoxin:Signal transduction histidine kinase:Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain:FOG: TPR repeat, SEL1 subfamily:Periplasmic protein TonB, links inner and outer membranes:NifU homolog involved in Fe-S cluster formation:ADP-heptose:LPS heptosyltransferase:Lactate dehydrogenase and related dehydrogenases:DnaJ-domain-containing proteins 1:ABC-type Fe3+ transport system, permease component:Outer membrane receptor proteins, mostly Fe transport:ABC-type Fe3+ transport system, periplasmic component:Putative multicopper oxidases:Uncharacterized iron-regulated protein:Uncharacterized iron-regulated protein:Predicted thiol oxidoreductase:Predicted periplasmic lipoprotein:Uncharacterized protein conserved in bacteria:Outer membrane receptor for Fe3+-dicitrate:Outer membrane receptor for monomeric catechols:Nucleotide transport and metabolism:Coenzyme transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:Cell wall/membrane/envelope biogenesis:Posttranslational modification, protein turnover, chaperones:Inorganic ion transport and metabolism:Lipopolysaccharide biosynthesis:Pyruvate metabolism:Metabolic pathways:ABC transporters:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:Function unknown:Signal transduction mechanisms:TIGR00049:hscB:tonB_Cterm:TonB-siderophor:HscA:iscU:fdx_isc:heptsyl_trn_II:Cations and iron carrying compounds:Transport and binding proteins:Protein folding and stabilization:Protein fate:Metabolism:Global:Membrane Transport:Environmental Information Processing:Glycan Biosynthesis and Metabolism:Carbohydrate Metabolism:Poorly characterized:Metabolism:Cellular processes and signaling:Information storage and processing:Metabolism:Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides:Cell envelope:Other:Biosynthesis of cofactors, prosthetic groups, and carriers:Porins" 99 "Thiamine monophosphate kinase:6-pyruvoyl-tetrahydropterin synthase:Transcription termination factor:Putative threonine efflux protein:DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog:Outer membrane receptor proteins, mostly Fe transport:Sugar phosphate permease:Predicted membrane protein:Uncharacterized iron-regulated membrane protein:Predicted aspartyl protease:Predicted transcriptional regulator:Fe2+-dicitrate sensor, membrane component:Outer membrane receptor for Fe3+-dicitrate:Amino acid transport and metabolism:Carbohydrate transport and metabolism:Coenzyme transport and metabolism:Transcription:Inorganic ion transport and metabolism:Thiamine metabolism:Folate biosynthesis:Metabolic pathways:RNA polymerase:General function prediction only:Function unknown:Signal transduction mechanisms:glpT:thiL:TonB-siderophor:nusB:clan_AA_DTGA:sigma70-ECF:queuosine_QueD:Thiamine:Biosynthesis of cofactors, prosthetic groups, and carriers:Porins:Other:Transport and binding proteins:Degradation of proteins, peptides, and glycopeptides:Protein fate:tRNA and rRNA base modification:Protein synthesis:Transcription factors:Transcription:Metabolism:Metabolism:Global:Transcription:Genetic Information Processing:Information storage and processing:Metabolism of Cofactors and Vitamins:Cellular processes and signaling:Metabolism:Poorly characterized" 100 "Energy production and conversion:1-acyl-sn-glycerol-3-phosphate acyltransferase:Kef-type K+ transport systems, membrane components:Sugar kinases, ribokinase family:Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases:Predicted phosphatases:Transcriptional regulator:Predicted membrane-associated Zn-dependent proteases 1:Uncharacterized conserved protein:Lactate dehydrogenase and related dehydrogenases:Gamma-aminobutyrate permease and related permeases:Branched-chain amino acid permeases:Transcriptional regulators of sugar metabolism:Transcriptional regulators:Acyl-CoA thioesterase:Sugar phosphate permease:Predicted carboxypeptidase:Uncharacterized membrane protein affecting hemolysin expression:Amino acid transport and metabolism:Nucleotide transport and metabolism:Carbohydrate transport and metabolism:Coenzyme transport and metabolism:Lipid transport and metabolism:Transcription:Cell wall/membrane/envelope biogenesis:Inorganic ion transport and metabolism:Pentose phosphate pathway:Glutathione metabolism:Biosynthesis of unsaturated fatty acids:Metabolic pathways:Microbial metabolism in diverse environments:General function prediction only:Function unknown:TIGR00054:tesB:TIGR00278:livcs:2a37:HAD-SF-IA-v3:Metabolism:Carbohydrate Metabolism:Lipid Metabolism:Metabolism of Other Amino Acids:Global:Metabolism:Fatty acid and phospholipid metabolism:Biosynthesis:Protein fate:Degradation of proteins, peptides, and glycopeptides:Transport and binding proteins:Amino acids, peptides and amines:Cations and iron carrying compounds:Hypothetical proteins:Conserved:Unknown function:Enzymes of unknown specificity:Information storage and processing:Cellular processes and signaling:Metabolism:Poorly characterized" 101 "Predicted epimerase, PhzC/PhzF homolog:Transcriptional regulator:16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases:Glycosyltransferases, probably involved in cell wall biogenesis:Putative threonine efflux protein:Transcriptional regulator:Transcriptional regulators:Predicted transcriptional regulator:Uncharacterized protein, possibly involved in aromatic compounds catabolism:Putative homoserine kinase type II (protein kinase fold):Arabinose efflux permease:Uncharacterized protein conserved in bacteria:Type III secretory pathway, component EscT:Type III secretory pathway, component EscU:Predicted integral membrane protein:Amino acid transport and metabolism:Carbohydrate transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:Cell wall/membrane/envelope biogenesis:Aminoacyl-tRNA biosynthesis:Bacterial secretion system:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:Function unknown:unchar_dom_1:PhzF_family:rrf2_super:fliR_like_III:FlhB_rel_III:LcrR:phn_lysR:efp_adjacent_2:Intracellular trafficking, secretion, and vesicular transport:Translation:Information storage and processing:Cellular processes and signaling:Metabolism:Poorly characterized:Genetic Information Processing:Unknown function:Pathogenesis:Toxin production and resistance:Cellular processes:Membrane Transport:Environmental Information Processing:General" 102 "Glutamate dehydrogenase/leucine dehydrogenase:Lactoylglutathione lyase and related lyases:FOG: CheY-like receiver:Acetyltransferases, including N-acetylases of ribosomal proteins:Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain:Glycine cleavage system regulatory protein:Outer membrane protein and related peptidoglycan-associated (lipo)proteins:Amino acid transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:Cell wall/membrane/envelope biogenesis:Valine leucine and isoleucine degradation:Valine leucine and isoleucine biosynthesis:Metabolic pathways:Biosynthesis of secondary metabolites:Two-component system:Bacterial chemotaxis:Signal transduction mechanisms:Information storage and processing:Amino Acid Metabolism:Environmental Information Processing:Signal Transduction:Cellular Processes:Cell Motility:Global:Metabolism:Metabolism:Cellular processes and signaling:Metabolism" 103 "Cysteine synthase:Mg-dependent DNase:Acetyltransferases:Uncharacterized membrane-associated protein:Membrane carboxypeptidase (penicillin-binding protein):ABC-type multidrug transport system, ATPase and permease components:Threonine dehydratase:16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases:Protein-disulfide isomerase:AraC-type DNA-binding domain-containing proteins:Membrane-bound lytic murein transglycosylase B:ABC-type transport system, involved in lipoprotein release, permease component:Predicted soluble lytic transglycosylase fused to an ABC-type amino acid-binding protein:Membrane-bound metallopeptidase:Cell cycle control, cell division, chromosome partitioning:Amino acid transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:Replication, recombination and repair:Cell wall/membrane/envelope biogenesis:Posttranslational modification, protein turnover, chaperones:Glycine serine and threonine metabolism:Cysteine and methionine metabolism:Valine leucine and isoleucine biosynthesis:Selenocompound metabolism:Peptidoglycan biosynthesis:Sulfur metabolism:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:ABC transporters:General function prediction only:Function unknown:TIGR00093:ilvA_2Cterm:cysKM:rimI:PBP_1b:MsbA_lipidA:lolCE:MltB:Defense mechanisms:Poorly characterized:Protein synthesis:Metabolism:Metabolism:Global:Membrane Transport:Environmental Information Processing:Glycan Biosynthesis and Metabolism:Metabolism of Other Amino Acids:Amino Acid Metabolism:Ribosomal proteins: synthesis and modification:Energy Metabolism:tRNA and rRNA base modification:Protein fate:Protein and peptide secretion and trafficking:Transport and binding proteins:Other:Amino acid biosynthesis:Pyruvate family:Serine family:Cell envelope:Biosynthesis and degradation of murein sacculus and peptidoglycan:Information storage and processing:Cellular processes and signaling:Metabolism" 104 "Chromatin structure and dynamics:Deacetylases, including yeast histone deacetylase and acetoin utilization protein:Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II:Dienelactone hydrolase and related enzymes:Spermidine/putrescine-binding periplasmic protein:Parvulin-like peptidyl-prolyl isomerase:Periplasmic protein TonB, links inner and outer membranes:Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases):ABC-type transport system involved in multi-copper enzyme maturation, permease component:Outer membrane protein:H+/gluconate symporter and related permeases:Arabinose efflux permease:Putative ammonia monooxygenase:Uncharacterized protein conserved in bacteria:ABC-type uncharacterized transport system involved in gliding motility, auxiliary component:Uncharacterized protein conserved in bacteria:Protocatechuate 3,4-dioxygenase beta subunit:Uncharacterized protein conserved in bacteria:Prophage antirepressor:ABC-type sugar transport systems, ATPase components:Muconolactone delta-isomerase:Amino acid transport and metabolism:Carbohydrate transport and metabolism:Lipid transport and metabolism:Transcription:Cell wall/membrane/envelope biogenesis:Cell motility:Posttranslational modification, protein turnover, chaperones:Synthesis and degradation of ketone bodies:Chlorocyclohexane and chlorobenzene degradation:Benzoate degradation:Fluorobenzoate degradation:Toluene degradation:Butanoate metabolism:Metabolic pathways:Microbial metabolism in diverse environments:ABC transporters:Two-component system:Bacterial secretion system:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:Function unknown:2A0106:tonB_Cterm:vgr_GE:outer_NodT:PHB_DH:catechol_proteo:Gneg_AbrB_dup:muco_delta:Intracellular trafficking, secretion, and vesicular transport:Poorly characterized:Metabolism:Cellular processes and signaling:Information storage and processing:Porins:Cations and iron carrying compounds:Unknown substrate:Transport and binding proteins:Other:Energy metabolism:Metabolism:Metabolism:Global:Signal Transduction:Membrane Transport:Environmental Information Processing:Xenobiotics Biodegradation and Metabolism:Lipid Metabolism:Carbohydrate Metabolism" 105 "Energy production and conversion:Adenylosuccinate lyase:Glycerophosphoryl diester phosphodiesterase:Membrane-associated phospholipid phosphatase:Cation/multidrug efflux pump:Membrane-fusion protein:Predicted acetyltransferases and hydrolases with the alpha/beta hydrolase fold:Outer membrane protein:Multidrug resistance efflux pump:Cytochrome c, mono- and diheme variants:Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain:Hemolysin activation/secretion protein:Predicted membrane protein:Urea transporter:Signal transduction histidine kinase:Amino acid transport and metabolism:Nucleotide transport and metabolism:Lipid transport and metabolism:Transcription:Cell wall/membrane/envelope biogenesis:Purine metabolism:Alanine aspartate and glutamate metabolism:Glycerophospholipid metabolism:Metabolic pathways:Biosynthesis of secondary metabolites:Two-component system:Bacterial secretion system:General function prediction only:Function unknown:Signal transduction mechanisms:2A0602:purB:gspI:RND_mfp:outer_NodT:Intracellular trafficking, secretion, and vesicular transport:Defense mechanisms:Cellular processes and signaling:Lipid Metabolism:Nucleotide Metabolism:Amino Acid Metabolism:Environmental Information Processing:Membrane Transport:Signal Transduction:Global:Metabolism:Purines, pyrimidines, nucleosides, and nucleotides:Purine ribonucleotide biosynthesis:Transport and binding proteins:Unknown substrate:Porins:Information storage and processing:Metabolism:Metabolism:Poorly characterized" 106 "Energy production and conversion:Adenylosuccinate lyase:Phosphoribosylformylglycinamidine (FGAM) synthase, synthetase domain:Isoleucyl-tRNA synthetase:Phosphoglycerate dehydrogenase and related dehydrogenases:Glycine/serine hydroxymethyltransferase:5,10-methylene-tetrahydrofolate dehydrogenase/Methenyl tetrahydrofolate cyclohydrolase:Superfamily I DNA and RNA helicases:Thiamine monophosphate synthase:Carbamoylphosphate synthase small subunit:IMP dehydrogenase/GMP reductase:Uridylate kinase:Glycyl-tRNA synthetase, alpha subunit:Flavodoxin reductases (ferredoxin-NADPH reductases) family 1:Transcriptional regulator:Fatty acid desaturase:Amino acid transport and metabolism:Nucleotide transport and metabolism:Coenzyme transport and metabolism:Lipid transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:Replication, recombination and repair:Purine metabolism:Pyrimidine metabolism:Alanine aspartate and glutamate metabolism:Glycine serine and threonine metabolism:Valine leucine and isoleucine biosynthesis:Cyanoamino acid metabolism:One carbon pool by folate:Methane metabolism:Carbon fixation pathways in prokaryotes:Thiamine metabolism:Aminoacyl-tRNA biosynthesis:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:glyQ:ileS:thiE:purB:rep:IMP_dehydrog:CPSaseIIsmall:FGAM_synt:pyrH_bact:Thiamine:Energy Metabolism:Nucleotide Metabolism:Amino Acid Metabolism:Metabolism of Other Amino Acids:Metabolism of Cofactors and Vitamins:Genetic Information Processing:Translation:Global:Metabolism:Purines, pyrimidines, nucleosides, and nucleotides:Nucleotide and nucleoside interconversions:Purine ribonucleotide biosynthesis:Pyrimidine ribonucleotide biosynthesis:DNA metabolism:DNA replication, recombination, and repair:Protein synthesis:tRNA aminoacylation:Biosynthesis of cofactors, prosthetic groups, and carriers:Metabolism:Information storage and processing:Metabolism" 107 "Energy production and conversion:Fumarase:Glutathione synthase/Ribosomal protein S6 modification enzyme (glutaminyl transferase):Asparagine synthase (glutamine-hydrolyzing):Uncharacterized homolog of Blt101:Predicted oxidoreductases (related to aryl-alcohol dehydrogenases):Aconitase A:D-alanine-D-alanine ligase and related ATP-grasp enzymes:Cellulase M and related proteins:Bacterioferritin (cytochrome b1):Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains:Putative NADPH-quinone reductase (modulator of drug activity B):3-carboxymuconate cyclase:Small-conductance mechanosensitive channel:Uncharacterized conserved protein:Signal transduction histidine kinase:Amino acid transport and metabolism:Carbohydrate transport and metabolism:Coenzyme transport and metabolism:Translation, ribosomal structure and biogenesis:Cell wall/membrane/envelope biogenesis:Inorganic ion transport and metabolism:Citrate cycle (TCA cycle):Alanine aspartate and glutamate metabolism:Glyoxylate and dicarboxylate metabolism:Carbon fixation pathways in prokaryotes:Nitrogen metabolism:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:Two-component system:General function prediction only:Function unknown:Signal transduction mechanisms:sensory_box:fumC_II:aconitase_1:asn_synth_AEB:trio_acet_GNAT:trio_M42_hydro:Poorly characterized:Metabolism:Cellular processes and signaling:Information storage and processing:Aspartate family:Amino acid biosynthesis:Small molecule interactions:Regulatory functions:TCA cycle:Energy metabolism:Metabolism:Metabolism:Global:Signal Transduction:Environmental Information Processing:Amino Acid Metabolism:Energy Metabolism:Carbohydrate Metabolism" 108 "Energy production and conversion:Transcriptional regulator:Glutathione S-transferase:Predicted transcriptional regulators:Glycine/D-amino acid oxidases (deaminating):Cation/multidrug efflux pump:Membrane-fusion protein:Outer membrane protein:NADH:flavin oxidoreductases, Old Yellow Enzyme family:Adenosine deaminase:Arabinose efflux permease:Uncharacterized protein conserved in bacteria:Uncharacterized protein conserved in bacteria:Uncharacterized conserved protein:Amino acid transport and metabolism:Nucleotide transport and metabolism:Carbohydrate transport and metabolism:Transcription:Cell wall/membrane/envelope biogenesis:Posttranslational modification, protein turnover, chaperones:Arginine and proline metabolism:Glutathione metabolism:Metabolic pathways:Function unknown:2A0602:RND_mfp:outer_NodT:Intracellular trafficking, secretion, and vesicular transport:Defense mechanisms:Global:Metabolism of Other Amino Acids:Amino Acid Metabolism:Metabolism:Poorly characterized:Metabolism:Cellular processes and signaling:Information storage and processing:Porins:Unknown substrate:Transport and binding proteins:Metabolism" 109 "Energy production and conversion:5-formyltetrahydrofolate cyclo-ligase:Deoxyribodipyrimidine photolyase:Transcriptional regulator:Mg2+ and Co2+ transporters:ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components:NADH:ubiquinone oxidoreductase subunit 3 (chain A):Biopolymer transport protein:Membrane protein TerC, possibly involved in tellurium resistance:Lysine efflux permease:Outer membrane receptor proteins, mostly Fe transport:Acetyltransferases, including N-acetylases of ribosomal proteins:Acyl-CoA dehydrogenases:Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases:Uncharacterized protein conserved in bacteria:Uncharacterized conserved protein:Uncharacterized component of phosphonate metabolism:Response regulator:Predicted signal transduction protein containing sensor and EAL domains:Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain:Conserved secreted protein:Coenzyme transport and metabolism:Lipid transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:Replication, recombination and repair:Inorganic ion transport and metabolism:Pentose phosphate pathway:Oxidative phosphorylation:One carbon pool by folate:Metabolic pathways:ABC transporters:General function prediction only:Function unknown:Signal transduction mechanisms:SsuA_fam:TonB-siderophor:phosphon_PhnN:MTHFS_bact:R_switched_Alx:Intracellular trafficking, secretion, and vesicular transport:Environmental Information Processing:Metabolism of Cofactors and Vitamins:Energy Metabolism:Poorly characterized:Carbohydrate Metabolism:Metabolism:Cellular processes and signaling:Information storage and processing:Porins:Other:Transport and binding proteins:Metabolism:Phosphorus compounds:One-carbon metabolism:Central intermediary metabolism:Metabolism:Global:Membrane Transport" 110 "Energy production and conversion:MoxR-like ATPases:Flavodoxin reductases (ferredoxin-NADPH reductases) family 1:Heme/copper-type cytochrome/quinol oxidase, subunit 3:Cytochrome c, mono- and diheme variants:Uncharacterized protein involved in response to NO:Nitric oxide reductase large subunit:Regulator of nitric oxide reductase transcription:Nitrous oxide reductase:Nitric oxide reductase activation protein:Transcription:Inorganic ion transport and metabolism:Nitrogen metabolism:Microbial metabolism in diverse environments:General function prediction only:TAT_signal_seq:Protein fate:Metabolism:Global:Poorly characterized:Energy Metabolism:Metabolism:Metabolism:Information storage and processing:Protein and peptide secretion and trafficking" 111 "Dihydroorotate dehydrogenase:FAD synthase:Thymidylate synthase:Glutamyl-tRNA reductase:Rhodanese-related sulfurtransferase:Predicted permeases:Inactive homolog of metal-dependent proteases, putative molecular chaperone:Sulfur transfer protein involved in thiamine biosynthesis:Predicted membrane protein:Uncharacterized conserved protein:Nucleotide transport and metabolism:Coenzyme transport and metabolism:Posttranslational modification, protein turnover, chaperones:Inorganic ion transport and metabolism:Pyrimidine metabolism:One carbon pool by folate:Riboflavin metabolism:Porphyrin and chlorophyll metabolism:Metabolic pathways:Biosynthesis of secondary metabolites:ABC transporters:Sulfur relay system:General function prediction only:Function unknown:ribF:HI0507:hemA:pyrD_sub2:thiS:thym_sym:bact_YeaZ:Riboflavin, FMN, and FAD:Thiamine:Cellular processes and signaling:Metabolism:Poorly characterized:Conserved:Hypothetical proteins:2'-Deoxyribonucleotide metabolism:Pyrimidine ribonucleotide biosynthesis:Purines, pyrimidines, nucleosides, and nucleotides:Metabolism:Global:Metabolism:Membrane Transport:Environmental Information Processing:Folding Sorting and Degradation:Genetic Information Processing:Metabolism of Cofactors and Vitamins:Biosynthesis of cofactors, prosthetic groups, and carriers:Nucleotide Metabolism:Heme, porphyrin, and cobalamin" 112 "Energy production and conversion:Acyl carrier protein:Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily):Spermidine/putrescine-binding periplasmic protein:Protease subunit of ATP-dependent Clp proteases:Predicted glycosyltransferases:Outer membrane protein:Multidrug resistance efflux pump:Glycosyl transferases, related to UDP-glucuronosyltransferase:AraC-type DNA-binding domain-containing proteins:ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain:Copper chaperone:DNA-binding HTH domain-containing proteins:Arabinose efflux permease:Zinc metalloprotease (elastase):Uncharacterized protein conserved in bacteria:N-acyl-L-homoserine lactone synthetase:Amino acid transport and metabolism:Carbohydrate transport and metabolism:Lipid transport and metabolism:Transcription:Cell wall/membrane/envelope biogenesis:Posttranslational modification, protein turnover, chaperones:Inorganic ion transport and metabolism:ABC transporters:Two-component system:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:Function unknown:Signal transduction mechanisms:acyl_carrier:rhamnosyltran:Intracellular trafficking, secretion, and vesicular transport:Defense mechanisms:Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides:Cell envelope:Biosynthesis:Fatty acid and phospholipid metabolism:Signal Transduction:Membrane Transport:Environmental Information Processing:Poorly characterized:Metabolism:Cellular processes and signaling:Information storage and processing" 113 "Energy production and conversion:Guanosine polyphosphate pyrophosphohydrolases/synthetases:Predicted metal-dependent hydrolase:Dihydroorotase:Valyl-tRNA synthetase:Preprotein translocase subunit SecA (ATPase, RNA helicase):DNA polymerase III, epsilon subunit and related 3'-5' exonucleases:ABC-type (unclassified) transport system, ATPase component:Polyribonucleotide nucleotidyltransferase (polynucleotide phosphorylase):Ribonucleases G and E:Phosphate starvation-inducible protein PhoH, predicted ATPase:Long-chain fatty acid transport protein:Monomeric isocitrate dehydrogenase:Putative Mg2+ and Co2+ transporter CorC:Nucleotide transport and metabolism:Lipid transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:Replication, recombination and repair:Inorganic ion transport and metabolism:Citrate cycle (TCA cycle):Purine metabolism:Pyrimidine metabolism:Valine leucine and isoleucine biosynthesis:Glutathione metabolism:Carbon fixation pathways in prokaryotes:Aminoacyl-tRNA biosynthesis:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:ABC transporters:RNA degradation:Protein export:Bacterial secretion system:General function prediction only:Signal transduction mechanisms:TIGR00043:monomer_idh:valS:spoT_relA:RNaseEG:pyrC_dimer:secA:RNaseT:polynuc_phos:Intracellular trafficking, secretion, and vesicular transport:Protein and peptide secretion and trafficking:Carbohydrate Metabolism:Energy Metabolism:Nucleotide Metabolism:Amino Acid Metabolism:Metabolism of Other Amino Acids:Genetic Information Processing:Translation:Folding Sorting and Degradation:Environmental Information Processing:Membrane Transport:Global:Metabolism:Energy metabolism:TCA cycle:Purines, pyrimidines, nucleosides, and nucleotides:Pyrimidine ribonucleotide biosynthesis:Transcription:Degradation of RNA:RNA processing:Protein synthesis:Other:tRNA aminoacylation:Protein fate:Metabolism:Cellular processes:Adaptations to atypical conditions:Information storage and processing:Cellular processes and signaling:Metabolism:Poorly characterized" 114 "Putative translation factor (SUA5):Trk-type K+ transport systems, membrane components:Predicted Na+-dependent transporter:ATPase components of ABC transporters with duplicated ATPase domains:Phosphoserine phosphatase:ABC-type amino acid transport/signal transduction systems, periplasmic component/domain:Predicted sulfurtransferase:Nicotinic acid mononucleotide adenylyltransferase:Gamma-aminobutyrate permease and related permeases:Dihydroneopterin aldolase:Uncharacterized enzyme of thiazole biosynthesis:Uncharacterized membrane protein required for alginate biosynthesis:Amino acid transport and metabolism:Coenzyme transport and metabolism:Translation, ribosomal structure and biogenesis:Inorganic ion transport and metabolism:Glycine serine and threonine metabolism:Methane metabolism:Thiamine metabolism:Nicotinate and nicotinamide metabolism:Folate biosynthesis:Metabolic pathways:Microbial metabolism in diverse environments:General function prediction only:Signal transduction mechanisms:cyt_tran_rel:serB:folB:TIGR00740:Folic acid:Energy Metabolism:Amino Acid Metabolism:Metabolism of Cofactors and Vitamins:Global:Metabolism:Unknown function:Enzymes of unknown specificity:Amino acid biosynthesis:Serine family:Biosynthesis of cofactors, prosthetic groups, and carriers:Metabolism:Information storage and processing:Cellular processes and signaling:Metabolism:Poorly characterized" 115 "ABC-type metal ion transport system, periplasmic component/surface adhesin:Non-ribosomal peptide synthetase modules and related proteins:ABC-type Mn2+/Zn2+ transport systems, permease components:ABC-type Mn/Zn transport systems, ATPase component:Protein related to penicillin acylase:Enterochelin esterase and related enzymes:Uncharacterized iron-regulated membrane protein:Predicted thioesterase involved in non-ribosomal peptide biosynthesis:Outer membrane receptor for ferric coprogen and ferric-rhodotorulic acid:Inorganic ion transport and metabolism:ABC transporters:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:Function unknown:AA-adenyl-dom:TonB-siderophor:Metabolism:Porins:Transport and binding proteins:Membrane Transport:Environmental Information Processing:Poorly characterized" 116 "Ribosomal protein L4:Ribosomal protein L23:Ribosomal protein L2:Ribosomal protein L22:Ribosomal protein S3:Ribosomal protein L14:Ribosomal protein L6P/L9E:Ribosomal protein S5:Ribosomal protein S19:Ribosomal protein S17:Ribosomal protein L16/L10E:Ribosomal protein L15:Preprotein translocase subunit SecY:Ribosomal protein L18:Ribosomal protein L30/L7E:Translation, ribosomal structure and biogenesis:Ribosome:Protein export:Bacterial secretion system:L18_bact:3a0501s007:rpsC_bact:rpsE_bact:rplV_bact:rpsS_bact:rplN_bact:rplO_bact:rplP_bact:rplB_bact:rpmD_bact:S17_bact:L6_bact:rplD_bact:Intracellular trafficking, secretion, and vesicular transport:Cellular processes and signaling:Translation:Folding Sorting and Degradation:Environmental Information Processing:Membrane Transport:Protein synthesis:Ribosomal proteins: synthesis and modification:Protein fate:Protein and peptide secretion and trafficking:Information storage and processing:Genetic Information Processing" 117 "Energy production and conversion:Lipoate-protein ligase A:Tyrosyl-tRNA synthetase:Superfamily I DNA and RNA helicases:Phosphatidylglycerophosphate synthase:Transcriptional regulator:Predicted permease:MoxR-like ATPases:Transcription elongation factor:ABC-type amino acid transport/signal transduction systems, periplasmic component/domain:Na+/alanine symporter:Uncharacterized conserved protein (some members contain a von Willebrand factor type A (vWA) domain):Rubredoxin:Acyl-CoA thioesterase:Transcriptional regulators:Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain:Lysophospholipase L1 and related esterases:Predicted endonuclease containing a URI domain:Exonuclease I:Uncharacterized protein involved in cysteine biosynthesis:Predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, permease component:Predicted protein-disulfide isomerase:Predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, ATPase component:Uncharacterized protein conserved in bacteria:Uncharacterized conserved protein:Amino acid transport and metabolism:Coenzyme transport and metabolism:Lipid transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:Replication, recombination and repair:Posttranslational modification, protein turnover, chaperones:Glycerophospholipid metabolism:Aminoacyl-tRNA biosynthesis:Biosynthesis of unsaturated fatty acids:Metabolic pathways:Ribosome:Nucleotide excision repair:Mismatch repair:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:Function unknown:Signal transduction mechanisms:tyrS:pgsA:agcS:uvrD:greB:Transcription factors:Transcription:DNA replication, recombination, and repair:DNA metabolism:Biosynthesis:Fatty acid and phospholipid metabolism:Metabolism:Global:Replication and Repair:Translation:Genetic Information Processing:Metabolism:Lipid Metabolism:Poorly characterized:Metabolism:Cellular processes and signaling:Information storage and processing:tRNA aminoacylation:Protein synthesis" 118 "Energy production and conversion:2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway):Transcriptional regulator:ABC-type nitrate/sulfonate/bicarbonate transport system, permease component:ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components:Succinate dehydrogenase/fumarate reductase, flavoprotein subunit:ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component:Ferredoxin:Predicted transcriptional regulators:FOG: HEAT repeat:Outer membrane receptor proteins, mostly Fe transport:Transcriptional regulators:Gentisate 1,2-dioxygenase:Uncharacterized protein conserved in bacteria:Protein involved in meta-pathway of phenol degradation:Transcription:Inorganic ion transport and metabolism:Tyrosine metabolism:Metabolic pathways:Microbial metabolism in diverse environments:ABC transporters:Secondary metabolites biosynthesis, transport and catabolism:Function unknown:TonB-siderophor:gentisate_1_2:Metabolism:Metabolism:Poorly characterized:Information storage and processing:Porins:Transport and binding proteins:Metabolism:Global:Membrane Transport:Environmental Information Processing:Amino Acid Metabolism" 119 "Energy production and conversion:Short-chain dehydrogenases of various substrate specificities:Transcriptional regulator:ABC-type Fe3+-siderophore transport system, permease component:Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases):ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components:Outer membrane receptor proteins, mostly Fe transport:ABC-type Fe3+ transport system, periplasmic component:Arabinose efflux permease:Uncharacterized protein conserved in bacteria:Cytochrome B561:Predicted acetyltransferase:Uncharacterized protein, possibly involved in utilization of glycolate and propanediol:Cbb3-type cytochrome oxidase, subunit 1:Fe2+-dicitrate sensor, membrane component:ABC-type Fe2+-enterobactin transport system, periplasmic component:ABC-type enterobactin transport system, permease component:Carbohydrate transport and metabolism:Coenzyme transport and metabolism:Lipid transport and metabolism:Transcription:Posttranslational modification, protein turnover, chaperones:Inorganic ion transport and metabolism:Oxidative phosphorylation:Metabolic pathways:ABC transporters:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:Function unknown:Signal transduction mechanisms:ccoN:TonB-siderophor:TonB-hemin:Porins:Transport and binding proteins:Electron transport:Energy metabolism:Metabolism:Global:Membrane Transport:Environmental Information Processing:Energy Metabolism:Metabolism:Poorly characterized:Metabolism:Cellular processes and signaling:Information storage and processing" 120 "Pseudouridylate synthase:Chemotaxis protein histidine kinase and related kinases:Shikimate kinase:FOG: CheY-like receiver:Chemotaxis signal transduction protein:Methyl-accepting chemotaxis protein:Methylase of chemotaxis methyl-accepting proteins:Uncharacterized protein containing LysM domain:Type II secretory pathway, prepilin signal peptidase PulO and related peptidases:Chemotaxis response regulator containing a CheY-like receiver domain and a methylesterase domain:Tfp pilus assembly protein PilN:Tfp pilus assembly protein PilO:Tfp pilus assembly protein PilP:Tfp pilus assembly protein FimV:Type II secretory pathway, component HofQ:Tfp pilus assembly protein, ATPase PilM:Tfp pilus assembly protein, ATPase PilU:Amino acid transport and metabolism:Translation, ribosomal structure and biogenesis:Cell motility:Posttranslational modification, protein turnover, chaperones:Phenylalanine tyrosine and tryptophan biosynthesis:Metabolic pathways:Biosynthesis of secondary metabolites:Two-component system:Function unknown:Signal transduction mechanisms:hisT_truA:pilM:pilT_fam:IV_pilus_PilQ:FimV_Cterm:Intracellular trafficking, secretion, and vesicular transport:Poorly characterized:Amino Acid Metabolism:Environmental Information Processing:Signal Transduction:Global:Metabolism:Protein synthesis:tRNA and rRNA base modification:Cellular processes:Chemotaxis and motility:Cell envelope:Surface structures:Information storage and processing:Cellular processes and signaling:Metabolism:Metabolism" 121 "Ketol-acid reductoisomerase:Seryl-tRNA synthetase:Putative translation initiation inhibitor, yjgF family:DNA polymerase sliding clamp subunit (PCNA homolog):Parvulin-like peptidyl-prolyl isomerase:D-alanyl-D-alanine carboxypeptidase:Phosphate starvation-inducible protein PhoH, predicted ATPase:Uncharacterized conserved protein:Rare lipoprotein B:Amino acid transport and metabolism:Coenzyme transport and metabolism:Translation, ribosomal structure and biogenesis:Replication, recombination and repair:Cell wall/membrane/envelope biogenesis:Posttranslational modification, protein turnover, chaperones:Purine metabolism:Pyrimidine metabolism:Valine leucine and isoleucine biosynthesis:Peptidoglycan biosynthesis:Pantothenate and CoA biosynthesis:Aminoacyl-tRNA biosynthesis:Metabolic pathways:Biosynthesis of secondary metabolites:DNA replication:Mismatch repair:Homologous recombination:Function unknown:Signal transduction mechanisms:TIGR00004:serS:ilvC:dnan:Information storage and processing:Nucleotide Metabolism:Amino Acid Metabolism:Glycan Biosynthesis and Metabolism:Metabolism of Cofactors and Vitamins:Genetic Information Processing:Translation:Replication and Repair:Global:Metabolism:DNA metabolism:DNA replication, recombination, and repair:Transcription:Degradation of RNA:Protein synthesis:tRNA aminoacylation:Amino acid biosynthesis:Pyruvate family:Metabolism:Cellular processes and signaling:Metabolism:Poorly characterized" 122 "Energy production and conversion:Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase:Aspartyl-tRNA synthetase:Inorganic pyrophosphatase:Translation elongation factor P (EF-P)/translation initiation factor 5A (eIF-5A):GTP cyclohydrolase I:Signal recognition particle GTPase:Rhodanese-related sulfurtransferase:Deoxycytidine deaminase:3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase:DnaK suppressor protein:Ribosomal protein L11 methylase:Surface lipoprotein:DNA uptake lipoprotein:Ornithine/acetylornithine aminotransferase:Amino acid transport and metabolism:Nucleotide transport and metabolism:Carbohydrate transport and metabolism:Coenzyme transport and metabolism:Translation, ribosomal structure and biogenesis:Cell wall/membrane/envelope biogenesis:Inorganic ion transport and metabolism:Oxidative phosphorylation:Pyrimidine metabolism:Lysine biosynthesis:Arginine and proline metabolism:Phenylalanine tyrosine and tryptophan biosynthesis:Vitamin B6 metabolism:Folate biosynthesis:Aminoacyl-tRNA biosynthesis:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:Protein export:Bacterial secretion system:General function prediction only:Signal transduction mechanisms:aroFGH:efp:folE:prmA:aspS_bact:argD:ffh:E4PD_g-proteo:dCTP_deam:dksA:OM_YfiO:Intracellular trafficking, secretion, and vesicular transport:Pyridoxine:Energy Metabolism:Nucleotide Metabolism:Amino Acid Metabolism:Metabolism of Cofactors and Vitamins:Genetic Information Processing:Translation:Folding Sorting and Degradation:Environmental Information Processing:Membrane Transport:Global:Metabolism:Purines, pyrimidines, nucleosides, and nucleotides:2'-Deoxyribonucleotide metabolism:Regulatory functions:Small molecule interactions:Protein synthesis:tRNA aminoacylation:Ribosomal proteins: synthesis and modification:Translation factors:Protein fate:Protein and peptide secretion and trafficking:Amino acid biosynthesis:Aromatic amino acid family:Biosynthesis of cofactors, prosthetic groups, and carriers:Folic acid:Metabolism:Information storage and processing:Cellular processes and signaling:Metabolism:Poorly characterized" 123 "3-polyprenyl-4-hydroxybenzoate decarboxylase and related decarboxylases:Aspartate-semialdehyde dehydrogenase:Geranylgeranyl pyrophosphate synthase:Exopolyphosphatase:Formamidopyrimidine-DNA glycosylase:Carbonic anhydrase:Recombinational DNA repair protein (RecF pathway):Predicted aminomethyltransferase related to GcvT:Aspartate/tyrosine/aromatic aminotransferase:Homoserine dehydrogenase:Zn-dependent protease with chaperone function:Adenylate kinase and related kinases:Transcriptional regulator:Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily):Uracil DNA glycosylase:Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases):Outer membrane receptor proteins, mostly Fe transport:Exonuclease VII small subunit:Predicted iron-dependent peroxidase:Predicted hydrolase of the alpha/beta superfamily:Uncharacterized protein conserved in bacteria:Uncharacterized protein conserved in bacteria:Predicted membrane protein:Amino acid transport and metabolism:Nucleotide transport and metabolism:Coenzyme transport and metabolism:Lipid transport and metabolism:Transcription:Replication, recombination and repair:Posttranslational modification, protein turnover, chaperones:Inorganic ion transport and metabolism:Fatty acid biosynthesis:Ubiquinone and other terpenoid-quinone biosynthesis:Purine metabolism:Glycine serine and threonine metabolism:Cysteine and methionine metabolism:Lysine biosynthesis:Arginine and proline metabolism:Terpenoid backbone biosynthesis:Nitrogen metabolism:Biosynthesis of unsaturated fatty acids:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:Base excision repair:Mismatch repair:Homologous recombination:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:Function unknown:TIGR00148:fpg:recR:ung:pro_imino_pep_1:xseB:adk:Dyp_perox_fam:asd_gamma:ygfZ_signature:exo_poly_only:Aspartate family:Amino acid biosynthesis:General:Unknown function:tRNA and rRNA base modification:Protein synthesis:DNA replication, recombination, and repair:Degradation of DNA:DNA metabolism:Nucleotide and nucleoside interconversions:Purines, pyrimidines, nucleosides, and nucleotides:Phosphorus compounds:Central intermediary metabolism:Metabolism:Metabolism:Global:Replication and Repair:Genetic Information Processing:Metabolism of Terpenoids and Polyketides:Metabolism of Cofactors and Vitamins:Amino Acid Metabolism:Nucleotide Metabolism:Lipid Metabolism:Poorly characterized:Energy Metabolism:Metabolism:Cellular processes and signaling:Information storage and processing" 124 "Energy production and conversion:Acyl carrier protein:Uncharacterized NAD(FAD)-dependent dehydrogenases:Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily):Predicted phosphatase/phosphohexomutase:Membrane proteins related to metalloendopeptidases:Protease subunit of ATP-dependent Clp proteases:Uncharacterized conserved protein:Glycosyl transferases, related to UDP-glucuronosyltransferase:Predicted carbamoyl transferase, NodU family:Copper chaperone:Zinc metalloprotease (elastase):Uncharacterized protein conserved in bacteria:Chitinase:Trans-aconitate methyltransferase:Amino acid transport and metabolism:Carbohydrate transport and metabolism:Lipid transport and metabolism:Cell wall/membrane/envelope biogenesis:Posttranslational modification, protein turnover, chaperones:Inorganic ion transport and metabolism:Aminoacyl-tRNA biosynthesis:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:Function unknown:acyl_carrier:HAD-SF-IA-v3:Intracellular trafficking, secretion, and vesicular transport:Translation:Poorly characterized:Metabolism:Cellular processes and signaling:Enzymes of unknown specificity:Unknown function:Biosynthesis:Fatty acid and phospholipid metabolism:Genetic Information Processing" 125 "Energy production and conversion:Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase]:Dihydrodipicolinate synthase/N-acetylneuraminate lyase:Biotin carboxylase:Transcriptional regulator:Glycine/D-amino acid oxidases (deaminating):Cation/multidrug efflux pump:Membrane-fusion protein:NAD-dependent aldehyde dehydrogenases:Enoyl-CoA hydratase/carnithine racemase:Acyl-CoA synthetase (NDP forming):Na+/H+-dicarboxylate symporters:Outer membrane protein:Uncharacterized proteins, homologs of lactam utilization protein B:Transcriptional regulators:Acyl-CoA dehydrogenases:Allophanate hydrolase subunit 2:Allophanate hydrolase subunit 1:Transcriptional regulators:Nitrate/nitrite transporter:Sugar phosphate permease:Choline dehydrogenase and related flavoproteins:Uncharacterized conserved small protein:Amino acid transport and metabolism:Carbohydrate transport and metabolism:Coenzyme transport and metabolism:Lipid transport and metabolism:Transcription:Cell wall/membrane/envelope biogenesis:Inorganic ion transport and metabolism:Fatty acid biosynthesis:Fatty acid metabolism:Valine leucine and isoleucine degradation:Geraniol degradation:Lysine biosynthesis:Lysine degradation:Arginine and proline metabolism:Phenylalanine metabolism:Benzoate degradation:Tryptophan metabolism:beta-Alanine metabolism:Pyruvate metabolism:Naphthalene degradation:Aminobenzoate degradation:Propanoate metabolism:Styrene degradation:Butanoate metabolism:Carbon fixation pathways in prokaryotes:Limonene and pinene degradation:Caprolactam degradation:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:Two-component system:General function prediction only:Function unknown:urea_amlyse_rel:2A0106:2A0602:RND_mfp:outer_NodT:Intracellular trafficking, secretion, and vesicular transport:Defense mechanisms:Unknown substrate:Carbohydrate Metabolism:Energy Metabolism:Lipid Metabolism:Amino Acid Metabolism:Metabolism of Other Amino Acids:Metabolism of Terpenoids and Polyketides:Xenobiotics Biodegradation and Metabolism:Environmental Information Processing:Signal Transduction:Global:Metabolism:Transport and binding proteins:Metabolism:Porins:Unknown function:General:Information storage and processing:Cellular processes and signaling:Metabolism:Poorly characterized" 126 "Predicted N6-adenine-specific DNA methylase:Predicted methyltransferases:ABC-type Fe3+-hydroxamate transport system, periplasmic component:Predicted membrane-associated Zn-dependent proteases 1:GTP cyclohydrolase II:Diacylglycerol kinase:Serine acetyltransferase:ADP-ribose pyrophosphatase:Branched-chain amino acid permeases:Uncharacterized membrane protein, required for colicin V production:Putative transcriptional regulator, homolog of Bvg accessory factor:Predicted transcriptional regulator:Multiple antibiotic transporter:Uncharacterized Zn-ribbon-containing protein involved in phosphonate metabolism:Negative regulator of beta-lactamase expression:Amino acid transport and metabolism:Nucleotide transport and metabolism:Coenzyme transport and metabolism:Transcription:Replication, recombination and repair:Cell wall/membrane/envelope biogenesis:Inorganic ion transport and metabolism:Cysteine and methionine metabolism:Phosphonate and phosphinate metabolism:Glycerolipid metabolism:Glycerophospholipid metabolism:Riboflavin metabolism:Pantothenate and CoA biosynthesis:Sulfur metabolism:Metabolic pathways:Microbial metabolism in diverse environments:ABC transporters:General function prediction only:TIGR00054:TIGR00096:ribA:baf:phnA:rrf2_super:livcs:cysE:Intracellular trafficking, secretion, and vesicular transport:Defense mechanisms:Metabolism:Energy Metabolism:Lipid Metabolism:Amino Acid Metabolism:Metabolism of Other Amino Acids:Metabolism of Cofactors and Vitamins:Environmental Information Processing:Membrane Transport:Global:Metabolism:Protein fate:Degradation of proteins, peptides, and glycopeptides:Transport and binding proteins:Amino acids, peptides and amines:Unknown function:Enzymes of unknown specificity:General:Amino acid biosynthesis:Serine family:Biosynthesis of cofactors, prosthetic groups, and carriers:Pantothenate and coenzyme A:Riboflavin, FMN, and FAD:Information storage and processing:Cellular processes and signaling:Metabolism:Poorly characterized" 127 "dGTP triphosphohydrolase:Glutathione S-transferase:Parvulin-like peptidyl-prolyl isomerase:Cation/multidrug efflux pump:Membrane-fusion protein:NAD-dependent protein deacetylases, SIR2 family:Uncharacterized conserved protein:Outer membrane protein:Inosine-uridine nucleoside N-ribohydrolase:Type II secretory pathway, ATPase PulE/Tfp pilus assembly pathway, ATPase PilB:Tfp pilus assembly protein, pilus retraction ATPase PilT:RTX toxins and related Ca2+-binding proteins:Adenylate cyclase:Streptogramin lyase:ABC-type protease/lipase transport system, ATPase and permease components:Dipeptidase:Amino acid transport and metabolism:Nucleotide transport and metabolism:Transcription:Cell wall/membrane/envelope biogenesis:Cell motility:Posttranslational modification, protein turnover, chaperones:Purine metabolism:Amino sugar and nucleotide sugar metabolism:Nicotinate and nicotinamide metabolism:Metabolic pathways:ABC transporters:Bacterial secretion system:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:Function unknown:dGTP_triPase:pilT_fam:RND_mfp:type_I_sec_PrtD:type_I_sec_TolC:Intracellular trafficking, secretion, and vesicular transport:Defense mechanisms:Cellular processes and signaling:Carbohydrate Metabolism:Nucleotide Metabolism:Metabolism of Cofactors and Vitamins:Environmental Information Processing:Membrane Transport:Global:Metabolism:Purines, pyrimidines, nucleosides, and nucleotides:Nucleotide and nucleoside interconversions:Protein fate:Protein and peptide secretion and trafficking:Transport and binding proteins:Unknown substrate:Porins:Cellular processes:Chemotaxis and motility:Information storage and processing:Metabolism:Metabolism:Poorly characterized" 128 "Energy production and conversion:Methyl-accepting chemotaxis protein:Acetyltransferases, including N-acetylases of ribosomal proteins:Uncharacterized protein involved in formation of periplasmic nitrate reductase:Response regulator containing a CheY-like receiver domain and an HD-GYP domain:Uncharacterized protein conserved in bacteria:Periplasmic nitrate reductase system, NapE component:Translation, ribosomal structure and biogenesis:Transcription:Cell motility:Inorganic ion transport and metabolism:Nitrogen metabolism:Two-component system:Bacterial chemotaxis:Function unknown:Signal transduction mechanisms:napF:nitrate_rd_NapE:Metabolism:Energy Metabolism:Environmental Information Processing:Signal Transduction:Cellular Processes:Cell Motility:Energy metabolism:Electron transport:Information storage and processing:Cellular processes and signaling:Metabolism:Poorly characterized" 129 "Xanthosine triphosphate pyrophosphatase:Predicted GTPase:dsRNA-specific ribonuclease:FOG: CheY-like receiver:Flagellar biosynthesis/type III secretory pathway ATPase:GTPase:ATPases involved in chromosome partitioning:Flagellar motor component:Flagellar biosynthesis/type III secretory pathway protein:Flagellar biosynthesis pathway, component FliP:Flagellar motor protein:Flagellar basal body-associated protein:Flagellar motor switch protein:Flagellar motor switch/type III secretory pathway protein:Flagellar biosynthesis pathway, component FliQ:Predicted acyltransferase:Chemotaxis protein:Flagellar biogenesis protein:Cell cycle control, cell division, chromosome partitioning:Nucleotide transport and metabolism:Transcription:Cell motility:Purine metabolism:Thiamine metabolism:Metabolic pathways:Two-component system:Bacterial chemotaxis:Flagellar assembly:General function prediction only:Signal transduction mechanisms:TIGR00042:small_GTP:fliI_yscN:fliP:fliM_switch:fliQ:RNaseIII:fliN:FliO_TIGR:GTPase_YsxC:Intracellular trafficking, secretion, and vesicular transport:Cellular processes:Nucleotide Metabolism:Metabolism of Cofactors and Vitamins:Environmental Information Processing:Signal Transduction:Cellular Processes:Cell Motility:Global:Metabolism:Energy metabolism:ATP-proton motive force interconversion:DNA metabolism:DNA replication, recombination, and repair:Transcription:RNA processing:Protein synthesis:Other:Metabolism:Chemotaxis and motility:Unknown function:General:Information storage and processing:Cellular processes and signaling:Metabolism:Poorly characterized" 130 "3,4-dihydroxy-2-butanone 4-phosphate synthase:3-phosphoglycerate kinase:Riboflavin synthase alpha chain:Cytosine deaminase and related metal-dependent hydrolases:Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2:Selenocysteine lyase:Uncharacterized membrane-associated protein:Glutamate racemase:7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase:ATP-dependent exoDNAse (exonuclease V) beta subunit (contains helicase and exonuclease domains):D-alanyl-D-alanine carboxypeptidase (penicillin-binding protein 4):SufE protein probably involved in Fe-S center assembly:Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains:Predicted protein-disulfide isomerase:Signal transduction histidine kinase regulating C4-dicarboxylate transport system:Amino acid transport and metabolism:Nucleotide transport and metabolism:Carbohydrate transport and metabolism:Coenzyme transport and metabolism:Replication, recombination and repair:Cell wall/membrane/envelope biogenesis:Posttranslational modification, protein turnover, chaperones:Glycolysis / Gluconeogenesis:D-Glutamine and D-glutamate metabolism:Peptidoglycan biosynthesis:Riboflavin metabolism:Folate biosynthesis:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:Two-component system:Homologous recombination:Sulfur relay system:General function prediction only:Function unknown:Signal transduction mechanisms:glut_race:ribE:ribB:recB:PBP4:folK:Biosynthesis and degradation of murein sacculus and peptidoglycan:Cell envelope:Riboflavin, FMN, and FAD:Folic acid:Biosynthesis of cofactors, prosthetic groups, and carriers:DNA replication, recombination, and repair:DNA metabolism:Metabolism:Metabolism:Global:Signal Transduction:Environmental Information Processing:Replication and Repair:Folding Sorting and Degradation:Genetic Information Processing:Metabolism of Cofactors and Vitamins:Glycan Biosynthesis and Metabolism:Metabolism of Other Amino Acids:Metabolism:Carbohydrate Metabolism:Poorly characterized:Cellular processes and signaling:Information storage and processing" 131 "Energy production and conversion:Xaa-Pro aminopeptidase:Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase]:Ribonuclease HII:Excinuclease ATPase subunit:Ribosomal protein S14:Predicted S-adenosylmethionine-dependent methyltransferase involved in bacterial cell division:NAD/FAD-utilizing enzyme apparently involved in cell division:Na+/proline symporter:1-deoxy-D-xylulose 5-phosphate reductoisomerase:Nitroreductase:Predicted sugar phosphate isomerase involved in capsule formation:Predicted permeases:Transcription termination factor:ATPases involved in chromosome partitioning:Predicted transcriptional regulators:Predicted transcriptional regulators:Stringent starvation protein B:F0F1-type ATP synthase, subunit I:Cell cycle control, cell division, chromosome partitioning:Amino acid transport and metabolism:Coenzyme transport and metabolism:Lipid transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:Replication, recombination and repair:Cell wall/membrane/envelope biogenesis:Valine leucine and isoleucine biosynthesis:Butanoate metabolism:C5-Branched dibasic acid metabolism:Pantothenate and CoA biosynthesis:Terpenoid backbone biosynthesis:Metabolic pathways:Biosynthesis of secondary metabolites:ABC transporters:Ribosome:RNA degradation:DNA replication:Nucleotide excision repair:General function prediction only:acolac_lg:gidA:gidB:parB_part:Dxr:kpsF:uvra:rho:sss:Metabolism:Carbohydrate Metabolism:Amino Acid Metabolism:Metabolism of Cofactors and Vitamins:Metabolism of Terpenoids and Polyketides:Genetic Information Processing:Translation:Folding Sorting and Degradation:Replication and Repair:Environmental Information Processing:Membrane Transport:Global:Metabolism:Energy metabolism:Sugars:DNA metabolism:DNA replication, recombination, and repair:Transcription:Transcription factors:Protein synthesis:tRNA and rRNA base modification:Transport and binding proteins:Cations and iron carrying compounds:Amino acid biosynthesis:Pyruvate family:Biosynthesis of cofactors, prosthetic groups, and carriers:Other:Information storage and processing:Cellular processes and signaling:Metabolism:Poorly characterized" 132 "Amino acid transporters:Branched-chain amino acid ABC-type transport system, permease components:Type II secretory pathway, component PulF:Outer membrane protein:Outer membrane receptor proteins, mostly Fe transport:Type II secretory pathway, pseudopilin PulG:Cyanate permease:Arabinose efflux permease:Predicted hydrolase of the alpha/beta superfamily:Type II secretory pathway, component PulM:Type II secretory pathway, component PulK:Phosphate-selective porin:ABC-type oligopeptide transport system, periplasmic component:ABC-type uncharacterized transport system, permease component:Predicted dienelactone hydrolase:ABC-type protease/lipase transport system, ATPase and permease components:Amino acid transport and metabolism:Carbohydrate transport and metabolism:Cell wall/membrane/envelope biogenesis:Cell motility:Inorganic ion transport and metabolism:ABC transporters:Bacterial secretion system:General function prediction only:2A0302:typeII_sec_gspG:type_I_sec_PrtD:type_I_hlyD:type_I_sec_TolC:GspF:urea_trans_UrtB:Intracellular trafficking, secretion, and vesicular transport:Amino acids, peptides and amines:Transport and binding proteins:Protein and peptide secretion and trafficking:Protein fate:Membrane Transport:Poorly characterized:Metabolism:Environmental Information Processing:Cellular processes and signaling:Pathogenesis:Cellular processes:Porins" 133 "Energy production and conversion:Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit:Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component, and related enzymes:Aldo/keto reductases, related to diketogulonate reductase:ABC-type branched-chain amino acid transport systems, periplasmic component:Membrane carboxypeptidase (penicillin-binding protein):Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit:O-Methyltransferase involved in polyketide biosynthesis:Uncharacterized protein conserved in bacteria:Amino acid transport and metabolism:Cell wall/membrane/envelope biogenesis:Glycolysis / Gluconeogenesis:Citrate cycle (TCA cycle):Valine leucine and isoleucine biosynthesis:Pyruvate metabolism:Butanoate metabolism:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:ABC transporters:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:Function unknown:PDH_E1_alph_x:Pyruvate dehydrogenase:Carbohydrate Metabolism:Amino Acid Metabolism:Environmental Information Processing:Membrane Transport:Global:Metabolism:Energy metabolism:Metabolism:Cellular processes and signaling:Metabolism:Poorly characterized" 134 "Dihydroorotase and related cyclic amidohydrolases:Putative GTPases (G3E family):ABC-type antimicrobial peptide transport system, permease component:Carbonic anhydrases/acetyltransferases, isoleucine patch superfamily:Biopolymer transport proteins:N-acetylmuramoyl-L-alanine amidase:ABC-type antimicrobial peptide transport system, ATPase component:Cobalamin biosynthesis protein CobN and related Mg-chelatases:Uncharacterized conserved protein:Outer membrane receptor proteins, mostly Fe transport:DnaK suppressor protein:Uncharacterized protein conserved in bacteria:Predicted membrane protein:Uncharacterized protein conserved in bacteria:Uncharacterized conserved protein:Outer membrane receptor for ferrienterochelin and colicins:Predicted permease, DMT superfamily:Nucleotide transport and metabolism:Coenzyme transport and metabolism:Cell wall/membrane/envelope biogenesis:Inorganic ion transport and metabolism:Pyrimidine metabolism:Porphyrin and chlorophyll metabolism:Metabolic pathways:General function prediction only:Function unknown:Signal transduction mechanisms:TonB-siderophor:dksA:Intracellular trafficking, secretion, and vesicular transport:Defense mechanisms:Nucleotide Metabolism:Metabolism:Poorly characterized:Metabolism:Cellular processes and signaling:Porins:Transport and binding proteins:Small molecule interactions:Regulatory functions:Metabolism:Global:Metabolism of Cofactors and Vitamins" 135 "tRNA-dihydrouridine synthase:Molecular chaperone:Transcriptional regulator:Organic radical activating enzymes:Predicted PP-loop superfamily ATPase:7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase:Inactive homolog of metal-dependent proteases, putative molecular chaperone:Micrococcal nuclease (thermonuclease) homologs:Beta-lactamase class C and other penicillin binding proteins:AraC-type DNA-binding domain-containing proteins:Uncharacterized Zn-ribbon-containing protein involved in phosphonate metabolism:Uncharacterized protein conserved in bacteria:Predicted membrane protein:Predicted SAM-dependent methyltransferase:Uncharacterized conserved protein:Transcriptional regulator of aromatic amino acids metabolism:Hydroxylase for synthesis of 2-methylthio-cis-ribozeatin in tRNA:Amino acid transport and metabolism:Nucleotide transport and metabolism:Coenzyme transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:Replication, recombination and repair:Posttranslational modification, protein turnover, chaperones:Inorganic ion transport and metabolism:Phosphonate and phosphinate metabolism:Folate biosynthesis:Aminoacyl-tRNA biosynthesis:Metabolic pathways:Microbial metabolism in diverse environments:General function prediction only:Function unknown:TIGR00364:HI0507:phnA:TIGR00740:folK:DnaA_homol_Hda:bact_YeaZ:Defense mechanisms:Folic acid:Biosynthesis of cofactors, prosthetic groups, and carriers:General:Enzymes of unknown specificity:Unknown function:Conserved:Hypothetical proteins:DNA replication, recombination, and repair:DNA metabolism:Metabolism:Metabolism:Global:Translation:Genetic Information Processing:Metabolism of Cofactors and Vitamins:Metabolism of Other Amino Acids:Poorly characterized:Metabolism:Cellular processes and signaling:Information storage and processing" 136 "Energy production and conversion:Selenocysteine lyase:Transcriptional regulator:Glycine/D-amino acid oxidases (deaminating):Predicted thioesterase:3-hydroxyacyl-CoA dehydrogenase:Uncharacterized conserved protein:Alcohol dehydrogenase, class IV:Acyl-CoA dehydrogenases:Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains:AraC-type DNA-binding domain-containing proteins:Predicted membrane protein:Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain:Amino acid transport and metabolism:Lipid transport and metabolism:Transcription:General function prediction only:Function unknown:Signal transduction mechanisms:Poorly characterized:Metabolism:Cellular processes and signaling:Information storage and processing" 137 "Glycine/serine hydroxymethyltransferase:2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway):Glycine cleavage system protein P (pyridoxal-binding), N-terminal domain:Glycine cleavage system T protein (aminomethyltransferase):Glycine cleavage system H protein (lipoate-binding):Glutathione S-transferase:Aspartate/tyrosine/aromatic aminotransferase:L-serine deaminase:Pterin-4a-carbinolamine dehydratase:4-hydroxyphenylpyruvate dioxygenase and related hemolysins:Phenylalanine-4-hydroxylase:Homogentisate 1,2-dioxygenase:Amino acid transport and metabolism:Coenzyme transport and metabolism:Posttranslational modification, protein turnover, chaperones:Ubiquinone and other terpenoid-quinone biosynthesis:Glycine serine and threonine metabolism:Cysteine and methionine metabolism:Tyrosine metabolism:Phenylalanine metabolism:Phenylalanine tyrosine and tryptophan biosynthesis:Novobiocin biosynthesis:Cyanoamino acid metabolism:Styrene degradation:One carbon pool by folate:Methane metabolism:Nitrogen metabolism:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:gcvP:gcvH:gcvT:sda_mono:hmgA:maiA:4HPPD:fum_ac_acetase:Phe4hydrox_mono:Energy Metabolism:Metabolism:Energy metabolism:Amino acids and amines:Glycolysis/gluconeogenesis:Cellular processes and signaling:Metabolism:Poorly characterized:Xenobiotics Biodegradation and Metabolism:Biosynthesis of Other Secondary Metabolites:Metabolism of Cofactors and Vitamins:Metabolism of Other Amino Acids:Metabolism:Amino Acid Metabolism:Global" 138 "Energy production and conversion:Dihydroorotase and related cyclic amidohydrolases:Glutamine synthetase:2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway):Glutamate dehydrogenase/leucine dehydrogenase:Predicted amidohydrolase:Acetyl-CoA hydrolase:Nucleoside-diphosphate-sugar epimerases:Amino acid transporters:Transcriptional regulator:Predicted oxidoreductases (related to aryl-alcohol dehydrogenases):Spermidine/putrescine-binding periplasmic protein:Transcriptional regulator:Amidases related to nicotinamidase:Transcriptional regulator:Transcriptional regulators:NADH:flavin oxidoreductases, Old Yellow Enzyme family:Uncharacterized conserved protein, contains double-stranded beta-helix domain:Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain:AraC-type DNA-binding domain-containing proteins:Endonuclease I:Uncharacterized conserved protein:2-hydroxychromene-2-carboxylate isomerase:Predicted N-formylglutamate amidohydrolase:Short-chain alcohol dehydrogenase of unknown specificity:Sigma54-dependent transcription regulator containing an AAA-type ATPase domain and a DNA-binding domain:Amino acid transport and metabolism:Nucleotide transport and metabolism:Carbohydrate transport and metabolism:Transcription:Replication, recombination and repair:Cell wall/membrane/envelope biogenesis:Pyrimidine metabolism:Alanine aspartate and glutamate metabolism:Arginine and proline metabolism:Tyrosine metabolism:beta-Alanine metabolism:Pantothenate and CoA biosynthesis:Nitrogen metabolism:Aminoacyl-tRNA biosynthesis:Metabolic pathways:Microbial metabolism in diverse environments:Two-component system:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:Function unknown:Signal transduction mechanisms:D-hydantoinase:HpaG-N-term:agmatine_aguB:YgfH_subfam:Information storage and processing:Polyamine biosynthesis:Central intermediary metabolism:Metabolism:Metabolism:Global:Signal Transduction:Environmental Information Processing:Translation:Genetic Information Processing:Metabolism of Cofactors and Vitamins:Metabolism of Other Amino Acids:Amino Acid Metabolism:Nucleotide Metabolism:Poorly characterized:Energy Metabolism:Metabolism:Cellular processes and signaling" 139 "Methionine aminopeptidase:2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase:Predicted epimerase, PhzC/PhzF homolog:Anthranilate/para-aminobenzoate synthases component II:Uncharacterized enzymes related to aldose 1-epimerase:RNase PH:Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain:Predicted transcriptional regulators:ADP-ribose pyrophosphatase:Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1:Predicted transcriptional regulators:Transcriptional regulators:FOG: HPt domain:AraC-type DNA-binding domain-containing proteins:Oligoketide cyclase/lipid transport protein:Uncharacterized protein conserved in bacteria:Uncharacterized conserved small protein:Amino acid transport and metabolism:Nucleotide transport and metabolism:Carbohydrate transport and metabolism:Coenzyme transport and metabolism:Lipid transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:Purine metabolism:Phenylalanine tyrosine and tryptophan biosynthesis:Terpenoid backbone biosynthesis:Metabolic pathways:Biosynthesis of secondary metabolites:Two-component system:General function prediction only:Function unknown:Signal transduction mechanisms:ispF:met_pdase_I:trpG_papA:PhzF_family:SoxR:RNasePH:Information storage and processing:Nucleotide Metabolism:Amino Acid Metabolism:Metabolism of Terpenoids and Polyketides:Environmental Information Processing:Signal Transduction:Global:Metabolism:Regulatory functions:DNA interactions:Transcription:RNA processing:Protein fate:Protein modification and repair:Cellular processes:Toxin production and resistance:Biosynthesis of cofactors, prosthetic groups, and carriers:Other:Metabolism:Cellular processes and signaling:Metabolism:Poorly characterized" 140 "Arginase/agmatinase/formimionoglutamate hydrolase, arginase family:Short-chain dehydrogenases of various substrate specificities:Predicted glutathione S-transferase:Transcriptional regulator:Glutathione S-transferase:Na+/glutamate symporter:Transcriptional regulator:Transcriptional regulator:Multidrug resistance efflux pump:Esterase/lipase:Predicted flavoprotein involved in K+ transport:Xanthine/uracil permeases:Predicted hydrolase of alkaline phosphatase superfamily:Uncharacterized conserved protein:Amino acid transport and metabolism:Nucleotide transport and metabolism:Transcription:Posttranslational modification, protein turnover, chaperones:Inorganic ion transport and metabolism:Histidine metabolism:Aminoacyl-tRNA biosynthesis:Metabolic pathways:General function prediction only:Function unknown:gltS:ncs2:hutG:RND_mfp:Defense mechanisms:Cellular processes and signaling:Information storage and processing:Nucleosides, purines and pyrimidines:Amino acids, peptides and amines:Unknown substrate:Transport and binding proteins:Amino acids and amines:Energy metabolism:Metabolism:Metabolism:Global:Translation:Genetic Information Processing:Amino Acid Metabolism:Poorly characterized:Metabolism" 141 "Energy production and conversion:Cysteine synthase:Peptide methionine sulfoxide reductase:Zn-dependent hydrolases, including glyoxylases:DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32):Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases:Predicted Rossmann fold nucleotide-binding protein:Predicted acyl-CoA transferases/carnitine dehydratase:Predicted ATPase related to phosphate starvation-inducible protein PhoH:Acyl dehydratase:Uncharacterized protein involved in propionate catabolism:AraC-type DNA-binding domain-containing proteins:TRAP-type uncharacterized transport system, periplasmic component:Pyrroloquinoline quinone (Coenzyme PQQ) biosynthesis protein C:Amino acid transport and metabolism:Coenzyme transport and metabolism:Lipid transport and metabolism:Transcription:Posttranslational modification, protein turnover, chaperones:Cysteine and methionine metabolism:Arginine and proline metabolism:Selenocompound metabolism:Propanoate metabolism:Sulfur metabolism:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:RNA polymerase:General function prediction only:Signal transduction mechanisms:msrA:cysKM:AcOrn-deacetyl:prpD:rpoS_proteo:Adaptations to atypical conditions:Cellular processes:Transcription factors:Transcription:Metabolism:Global:Metabolism:Transcription:Genetic Information Processing:Metabolism of Other Amino Acids:Amino Acid Metabolism:Energy Metabolism:Glutamate family:Carbohydrate Metabolism:Serine family:Information storage and processing:Cellular processes and signaling:Metabolism:Poorly characterized:Amino acid biosynthesis" 142 "ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component:ABC-type dipeptide/oligopeptide/nickel transport systems, permease components:ABC-type dipeptide transport system, periplasmic component:Gamma-aminobutyrate permease and related permeases:ABC-type dipeptide/oligopeptide/nickel transport systems, permease components:Imidazolonepropionase and related amidohydrolases:Purine-cytosine permease and related proteins:ABC-type proline/glycine betaine transport systems, periplasmic components:Choline dehydrogenase and related flavoproteins:Histidine ammonia-lyase:N-formylglutamate amidohydrolase:ABC-type proline/glycine betaine transport system, ATPase component:ABC-type proline/glycine betaine transport system, permease component:Amino acid transport and metabolism:Nucleotide transport and metabolism:Inorganic ion transport and metabolism:Glycine serine and threonine metabolism:Histidine metabolism:Nitrogen metabolism:Metabolic pathways:ABC transporters:Bacterial chemotaxis:Secondary metabolites biosynthesis, transport and catabolism:proV:hutI:hutH:oligo_HPY:hutG_amidohyd:Amino acids and amines:Energy metabolism:Metabolism:Metabolism:Global:Cell Motility:Cellular Processes:Membrane Transport:Environmental Information Processing:Amino Acid Metabolism:Metabolism:Energy Metabolism:Amino acids, peptides and amines:Transport and binding proteins" 143 "4-hydroxybenzoate polyprenyltransferase and related prenyltransferases:Glycine cleavage system T protein (aminomethyltransferase):Superfamily II DNA and RNA helicases:Transcriptional regulator:Predicted PP-loop superfamily ATPase:Biopolymer transport proteins:ABC-type amino acid transport/signal transduction systems, periplasmic component/domain:Transcriptional regulator:Transcriptional regulator:Acyl-CoA hydrolase:Transcriptional regulators:Conserved protein/domain typically associated with flavoprotein oxygenases, DIM6/NTAB family:Uncharacterized conserved protein:Protein involved in catabolism of external DNA:Uncharacterized protein conserved in bacteria:Uncharacterized protein conserved in bacteria:Amino acid transport and metabolism:Coenzyme transport and metabolism:Lipid transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:Replication, recombination and repair:Ubiquinone and other terpenoid-quinone biosynthesis:Glycine serine and threonine metabolism:One carbon pool by folate:Nitrogen metabolism:Aminoacyl-tRNA biosynthesis:Metabolic pathways:Biosynthesis of secondary metabolites:ABC transporters:General function prediction only:Function unknown:Signal transduction mechanisms:TIGR00364:gcvT:ubiA_proteo:pcaR_pcaU:Intracellular trafficking, secretion, and vesicular transport:Information storage and processing:Energy Metabolism:Amino Acid Metabolism:Metabolism of Cofactors and Vitamins:Genetic Information Processing:Translation:Environmental Information Processing:Membrane Transport:Global:Metabolism:Energy metabolism:Amino acids and amines:Regulatory functions:DNA interactions:Unknown function:General:Biosynthesis of cofactors, prosthetic groups, and carriers:Menaquinone and ubiquinone:Metabolism:Cellular processes and signaling:Metabolism:Poorly characterized" 144 "Ketol-acid reductoisomerase:Phosphoheptose isomerase:3-oxoacyl-(acyl-carrier-protein) synthase:Lipoate synthase:DNA polymerase sliding clamp subunit (PCNA homolog):3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratases:Lipoproteins:D-alanyl-D-alanine carboxypeptidase:Uncharacterized conserved protein:Rare lipoprotein B:Uncharacterized protein conserved in bacteria:Amino acid transport and metabolism:Carbohydrate transport and metabolism:Coenzyme transport and metabolism:Lipid transport and metabolism:Replication, recombination and repair:Cell wall/membrane/envelope biogenesis:Fatty acid biosynthesis:Purine metabolism:Pyrimidine metabolism:Valine leucine and isoleucine biosynthesis:Lipopolysaccharide biosynthesis:Peptidoglycan biosynthesis:Pantothenate and CoA biosynthesis:Lipoic acid metabolism:Metabolic pathways:Biosynthesis of secondary metabolites:DNA replication:Mismatch repair:Homologous recombination:Secondary metabolites biosynthesis, transport and catabolism:Function unknown:rlpA:ilvC:lipA:dnan:fabA:Other:Lipid Metabolism:Nucleotide Metabolism:Amino Acid Metabolism:Glycan Biosynthesis and Metabolism:Metabolism of Cofactors and Vitamins:Genetic Information Processing:Replication and Repair:Global:Metabolism:Fatty acid and phospholipid metabolism:Biosynthesis:DNA metabolism:DNA replication, recombination, and repair:Amino acid biosynthesis:Pyruvate family:Biosynthesis of cofactors, prosthetic groups, and carriers:Lipoate:Cell envelope:Metabolism:Information storage and processing:Cellular processes and signaling:Metabolism:Poorly characterized" 145 "Energy production and conversion:Isopropylmalate/homocitrate/citramalate synthases:Adenosylmethionine-8-amino-7-oxononanoate aminotransferase:Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II:Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases:Citrate synthase:Predicted transcriptional regulators:NAD-dependent aldehyde dehydrogenases:Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases):Aconitase A:Gamma-aminobutyrate permease and related permeases:Acyl-CoA dehydrogenases:3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases:PEP phosphonomutase and related enzymes:Uncharacterized protein conserved in bacteria:Urocanate hydratase:Acetyl/propionyl-CoA carboxylase, alpha subunit:Amino acid transport and metabolism:Carbohydrate transport and metabolism:Coenzyme transport and metabolism:Lipid transport and metabolism:Transcription:Glycolysis / Gluconeogenesis:Citrate cycle (TCA cycle):Synthesis and degradation of ketone bodies:Valine leucine and isoleucine degradation:Geraniol degradation:Histidine metabolism:beta-Alanine metabolism:Inositol phosphate metabolism:Pyruvate metabolism:Naphthalene degradation:Glyoxylate and dicarboxylate metabolism:Propanoate metabolism:Butanoate metabolism:Methane metabolism:Carbon fixation pathways in prokaryotes:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:Function unknown:hutU:HIBADH:MMSDH:GABAperm:cit_synth_II:prpB:2met_isocit_dHY:prpF:Carbohydrate Metabolism:Energy metabolism:Amino acids and amines:Fermentation:Transport and binding proteins:Amino acids, peptides and amines:Information storage and processing:Metabolism:Poorly characterized:Metabolism:Global:Xenobiotics Biodegradation and Metabolism:Metabolism of Terpenoids and Polyketides:Metabolism of Other Amino Acids:Amino Acid Metabolism:Lipid Metabolism:Energy Metabolism:Metabolism" 146 "Glycine/serine hydroxymethyltransferase:2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway):Acetyl-CoA acetyltransferase:Glycine cleavage system protein P (pyridoxal-binding), N-terminal domain:Glycine cleavage system T protein (aminomethyltransferase):Glycine cleavage system H protein (lipoate-binding):Uncharacterized proteins, homologs of lactam utilization protein B:L-serine deaminase:Acyl CoA:acetate/3-ketoacid CoA transferase, alpha subunit:Allophanate hydrolase subunit 2:Allophanate hydrolase subunit 1:Acyl CoA:acetate/3-ketoacid CoA transferase, beta subunit:Sugar phosphate permease:4-hydroxyphenylpyruvate dioxygenase and related hemolysins:Homogentisate 1,2-dioxygenase:Predicted outer membrane protein:Uncharacterized conserved protein:Amino acid transport and metabolism:Carbohydrate transport and metabolism:Lipid transport and metabolism:Fatty acid metabolism:Synthesis and degradation of ketone bodies:Ubiquinone and other terpenoid-quinone biosynthesis:Glycine serine and threonine metabolism:Cysteine and methionine metabolism:Valine leucine and isoleucine degradation:Lysine degradation:Tyrosine metabolism:Phenylalanine metabolism:Benzoate degradation:Tryptophan metabolism:Cyanoamino acid metabolism:Pyruvate metabolism:Glyoxylate and dicarboxylate metabolism:Propanoate metabolism:Styrene degradation:Butanoate metabolism:One carbon pool by folate:Methane metabolism:Carbon fixation pathways in prokaryotes:Terpenoid backbone biosynthesis:Nitrogen metabolism:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:Two-component system:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:Function unknown:gcvP:gcvH:gcvT:sda_mono:hmgA:4HPPD:fum_ac_acetase:AcCoA-C-Actrans:pcaJ_scoB_fam:pcaI_scoA_fam:Energy metabolism:Metabolism:Global:Signal Transduction:Environmental Information Processing:Xenobiotics Biodegradation and Metabolism:Metabolism of Terpenoids and Polyketides:Metabolism of Cofactors and Vitamins:Metabolism of Other Amino Acids:Amino Acid Metabolism:Lipid Metabolism:Metabolism:Energy Metabolism:Other:Carbohydrate Metabolism:Metabolism:Poorly characterized:Fatty acid and phospholipid metabolism:Glycolysis/gluconeogenesis:Amino acids and amines" 147 "DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog:Predicted membrane protein:Outer membrane protein and related peptidoglycan-associated (lipo)proteins:Negative regulator of sigma E activity:Predicted outer membrane lipoprotein:Response regulator of the LytR/AlgR family:Transcription:Cell wall/membrane/envelope biogenesis:Two-component system:RNA polymerase:Function unknown:Signal transduction mechanisms:TIGR02448:sigma70-ECF:Poorly characterized:Transcription:Environmental Information Processing:Signal Transduction:Information storage and processing:Cellular processes and signaling:Genetic Information Processing" 148 "Energy production and conversion:Putative translation initiation inhibitor, yjgF family:Uncharacterized NAD(FAD)-dependent dehydrogenases:Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily):Esterase/lipase:Na+/glutamate symporter:ABC-type amino acid transport/signal transduction systems, periplasmic component/domain:Sulfite oxidase and related enzymes:Permeases:Sugar phosphate permease:Cbb3-type cytochrome oxidase, subunit 1:Thiosulfate reductase cytochrome B subunit (membrane anchoring protein):Uncharacterized protein conserved in bacteria:Amino acid transport and metabolism:Carbohydrate transport and metabolism:Lipid transport and metabolism:Translation, ribosomal structure and biogenesis:Posttranslational modification, protein turnover, chaperones:Oxidative phosphorylation:Metabolic pathways:ABC transporters:General function prediction only:Function unknown:Signal transduction mechanisms:gltS:ccoN:XapX:Metabolism:Cellular processes and signaling:Information storage and processing:General:Unknown function:Amino acids, peptides and amines:Transport and binding proteins:Electron transport:Energy metabolism:Metabolism:Metabolism:Global:Membrane Transport:Environmental Information Processing:Poorly characterized:Energy Metabolism" 149 "Predicted metal-dependent protease of the PAD1/JAB1 superfamily:Negative regulator of beta-lactamase expression:Predicted chitinase:Phage-related protein:Phage-related protein:Phage-related protein, tail component:General function prediction only:Function unknown:phage_tail_L:Defense mechanisms:Poorly characterized:Cellular processes and signaling:Prophage functions:Mobile and extrachromosomal element functions" 150 "Asp-tRNAAsn/Glu-tRNAGln amidotransferase B subunit (PET112 homolog):DNA-directed RNA polymerase, beta subunit/140 kD subunit:DNA-directed RNA polymerase, beta' subunit/160 kD subunit:Histidyl-tRNA synthetase:Cytidylate kinase:Carbamoylphosphate synthase large subunit (split gene in MJ):Cystathionine beta-lyases/cystathionine gamma-synthases:N6-adenine-specific methylase:Enzyme involved in the deoxyxylulose pathway of isoprenoid biosynthesis:FKBP-type peptidyl-prolyl cis-trans isomerases 2:A/G-specific DNA glycosylase:N-acetylglutamate synthase (N-acetylornithine aminotransferase):Predicted deacylase:ABC-type histidine transport system, ATPase component:Amino acid transport and metabolism:Nucleotide transport and metabolism:Lipid transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:Replication, recombination and repair:Posttranslational modification, protein turnover, chaperones:Purine metabolism:Pyrimidine metabolism:Alanine aspartate and glutamate metabolism:Cysteine and methionine metabolism:Arginine and proline metabolism:Terpenoid backbone biosynthesis:Aminoacyl-tRNA biosynthesis:Metabolic pathways:Biosynthesis of secondary metabolites:ABC transporters:RNA polymerase:Base excision repair:General function prediction only:cmk:TIGR00095:ArgJ:gatB:hisS:ispG_gcpE:mutY:O_suc_HS_sulf:CPSaseII_lrg:rpoB:rpoC_TIGR:Glutamate family:Nucleotide Metabolism:Amino Acid Metabolism:Metabolism of Terpenoids and Polyketides:Genetic Information Processing:Transcription:Translation:Replication and Repair:Environmental Information Processing:Membrane Transport:Global:Metabolism:Purines, pyrimidines, nucleosides, and nucleotides:Nucleotide and nucleoside interconversions:Pyrimidine ribonucleotide biosynthesis:DNA metabolism:DNA replication, recombination, and repair:Transcription:DNA-dependent RNA polymerase:Protein synthesis:tRNA aminoacylation:tRNA and rRNA base modification:Amino acid biosynthesis:Aspartate family:Metabolism:Biosynthesis of cofactors, prosthetic groups, and carriers:Other:Information storage and processing:Cellular processes and signaling:Metabolism:Poorly characterized" 151 "Energy production and conversion:Arginase/agmatinase/formimionoglutamate hydrolase, arginase family:Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase]:FAD/FMN-containing dehydrogenases:ATPase components of ABC transporters with duplicated ATPase domains:Transcriptional regulator:Na+/proline symporter:ABC-type Fe3+-hydroxamate transport system, periplasmic component:Glutathione S-transferase:ABC-type amino acid transport system, permease component:Methyl-accepting chemotaxis protein:Membrane protein TerC, possibly involved in tellurium resistance:ABC-type polar amino acid transport system, ATPase component:Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs:Recombinational DNA repair protein (RecF pathway):Purine-cytosine permease and related proteins:Transcriptional regulators:Pyridoxal/pyridoxine/pyridoxamine kinase:Predicted ornithine cyclodeaminase, mu-crystallin homolog:3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase:Ketosteroid isomerase homolog:Amino acid transport and metabolism:Nucleotide transport and metabolism:Coenzyme transport and metabolism:Transcription:Replication, recombination and repair:Cell motility:Posttranslational modification, protein turnover, chaperones:Inorganic ion transport and metabolism:Valine leucine and isoleucine biosynthesis:Arginine and proline metabolism:Phenylalanine tyrosine and tryptophan biosynthesis:Glutathione metabolism:Butanoate metabolism:C5-Branched dibasic acid metabolism:Vitamin B6 metabolism:Pantothenate and CoA biosynthesis:Metabolic pathways:Biosynthesis of secondary metabolites:ABC transporters:Two-component system:Bacterial chemotaxis:Homologous recombination:General function prediction only:Function unknown:Signal transduction mechanisms:reco:pyridox_kin:agmatinase:DAHP_synth_II:HEQRo_perm_3TM:DNA metabolism:Metabolism:Global:Cell Motility:Cellular Processes:Signal Transduction:Metabolism:Membrane Transport:Environmental Information Processing:Replication and Repair:Genetic Information Processing:Metabolism of Cofactors and Vitamins:Metabolism of Other Amino Acids:Amino Acid Metabolism:Pyridoxine:Carbohydrate Metabolism:Information storage and processing:Cellular processes and signaling:Metabolism:Poorly characterized:Biosynthesis of cofactors, prosthetic groups, and carriers:Aromatic amino acid family:Amino acid biosynthesis:Amino acids, peptides and amines:Transport and binding proteins:DNA replication, recombination, and repair" 152 "Energy production and conversion:tRNA-dihydrouridine synthase:Anaerobic dehydrogenases, typically selenocysteine-containing:Ribosomal protein L31:Asparagine synthase (glutamine-hydrolyzing):Peroxiredoxin:Thioredoxin reductase:Methionine synthase II (cobalamin-independent):Glycine/D-amino acid oxidases (deaminating):FOG: Ankyrin repeat:Catalase:Cation/multidrug efflux pump:Membrane-fusion protein:Amidases related to nicotinamidase:Predicted transcriptional regulators:Uncharacterized protein required for formate dehydrogenase activity:Outer membrane protein:Predicted membrane protein:Predicted membrane protein:Alkyl hydroperoxide reductase, large subunit:Amino acid transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:Cell wall/membrane/envelope biogenesis:Posttranslational modification, protein turnover, chaperones:Inorganic ion transport and metabolism:Pyrimidine metabolism:Alanine aspartate and glutamate metabolism:Cysteine and methionine metabolism:Tryptophan metabolism:Glyoxylate and dicarboxylate metabolism:Methane metabolism:Nitrogen metabolism:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:Ribosome:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:Function unknown:L31:fdhD_narQ:yjbN:rpmJ_bact:TRX_reduct:met_syn_B12ind:asn_synth_AEB:Fdhalpha-like:RND_mfp:outer_NodT:AhpF:Intracellular trafficking, secretion, and vesicular transport:Defense mechanisms:Global:Translation:Genetic Information Processing:Amino Acid Metabolism:Nucleotide Metabolism:Energy Metabolism:tRNA and rRNA base modification:Carbohydrate Metabolism:Transport and binding proteins:Unknown substrate:Porins:Cellular processes:Adaptations to atypical conditions:Amino acid biosynthesis:Aspartate family:Information storage and processing:Cellular processes and signaling:Metabolism:Poorly characterized:Ribosomal proteins: synthesis and modification:Protein synthesis:Electron transport:Energy metabolism:Metabolism:Metabolism" 153 "Energy production and conversion:Acetyltransferases:Uncharacterized homolog of gamma-carboxymuconolactone decarboxylase subunit:Methyl-accepting chemotaxis protein:Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes:Uncharacterized protein conserved in bacteria:AraC-type DNA-binding domain-containing proteins:Uncharacterized protein conserved in bacteria:Xanthine dehydrogenase, iron-sulfur cluster and FAD-binding subunit A:Xanthine dehydrogenase, molybdopterin-binding subunit B:Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain:Nucleotide transport and metabolism:Transcription:Cell motility:Glycolysis / Gluconeogenesis:Citrate cycle (TCA cycle):Purine metabolism:Glycine serine and threonine metabolism:Valine leucine and isoleucine degradation:Pyruvate metabolism:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:Two-component system:Bacterial chemotaxis:General function prediction only:Function unknown:Signal transduction mechanisms:sensory_box:ahpD_dom:lipoamide_DH:xanthine_xdhA:xanthine_xdhB:Cellular processes and signaling:Metabolism:Poorly characterized:General:Unknown function:Small molecule interactions:Regulatory functions:Metabolism:Other:Purines, pyrimidines, nucleosides, and nucleotides:Global:Cell Motility:Cellular Processes:Metabolism:Signal Transduction:Environmental Information Processing:Amino Acid Metabolism:Nucleotide Metabolism:Information storage and processing:Carbohydrate Metabolism" 154 "Energy production and conversion:Fumarase:Acyl-CoA dehydrogenases:Bacterioferritin (cytochrome b1):Putative NADPH-quinone reductase (modulator of drug activity B):Outer membrane protein and related peptidoglycan-associated (lipo)proteins:Uncharacterized conserved protein:Predicted membrane protein:Lipid transport and metabolism:Cell wall/membrane/envelope biogenesis:Inorganic ion transport and metabolism:Citrate cycle (TCA cycle):Fatty acid metabolism:Carbon fixation pathways in prokaryotes:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:General function prediction only:Function unknown:fumC_II:PHA_granule_1:Biosynthesis:Carbohydrate Metabolism:Energy Metabolism:Lipid Metabolism:Global:Metabolism:Energy metabolism:TCA cycle:Fatty acid and phospholipid metabolism:Metabolism:Cellular processes and signaling:Metabolism:Poorly characterized" 155 "Energy production and conversion:F0F1-type ATP synthase, beta subunit:F0F1-type ATP synthase, alpha subunit:F0F1-type ATP synthase, gamma subunit:F0F1-type ATP synthase, epsilon subunit (mitochondrial delta subunit):F0F1-type ATP synthase, subunit a:F0F1-type ATP synthase, subunit b:F0F1-type ATP synthase, delta subunit (mitochondrial oligomycin sensitivity protein):Cytochrome c1:Oxidative phosphorylation:Metabolic pathways:atpA:atpD:ATP_synt_6_or_A:ATP_synt_b:ATP_synt_delta:ATPsyn_F1gamma:ATP_synt_epsi:ATP_synt_c:Metabolism:ATP-proton motive force interconversion:Energy metabolism:Metabolism:Metabolism:Global:Energy Metabolism" 156 "Energy production and conversion:Predicted flavoprotein:Glycosyltransferase:Transcriptional regulator:Spermidine/putrescine-binding periplasmic protein:Mg-chelatase subunit ChlD:Multidrug resistance efflux pump:Outer membrane receptor proteins, mostly Fe transport:Mn2+ and Fe2+ transporters of the NRAMP family:Transposase and inactivated derivatives:4-hydroxyphenylpyruvate dioxygenase and related hemolysins:Ethanolamine utilization protein:Uncharacterized conserved protein:Predicted membrane protein:Protein involved in meta-pathway of phenol degradation:Amino acid transport and metabolism:Coenzyme transport and metabolism:Transcription:Replication, recombination and repair:Cell wall/membrane/envelope biogenesis:Inorganic ion transport and metabolism:Ubiquinone and other terpenoid-quinone biosynthesis:Tyrosine metabolism:Phenylalanine metabolism:Bisphenol degradation:Porphyrin and chlorophyll metabolism:Metabolic pathways:Microbial metabolism in diverse environments:ABC transporters:General function prediction only:Function unknown:nramp:RND_mfp:TonB-siderophor:FMN_reduc_MsuE:Defense mechanisms:Metabolism:Amino Acid Metabolism:Metabolism of Cofactors and Vitamins:Xenobiotics Biodegradation and Metabolism:Environmental Information Processing:Membrane Transport:Global:Metabolism:Transport and binding proteins:Unknown substrate:Cations and iron carrying compounds:Porins:Information storage and processing:Cellular processes and signaling:Metabolism:Poorly characterized" 157 "Energy production and conversion:2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway):Membrane protease subunits, stomatin/prohibitin homologs:Adenylate kinase and related kinases:Transcriptional regulator:Predicted Fe-S-cluster oxidoreductase:Outer membrane protein:ABC-type amino acid transport/signal transduction systems, periplasmic component/domain:NAD-dependent aldehyde dehydrogenases:NADH:flavin oxidoreductases, Old Yellow Enzyme family:Acyl-CoA dehydrogenases:Sulfite oxidase and related enzymes:AraC-type DNA-binding domain-containing proteins:Sugar phosphate permease:Predicted membrane protein:Uncharacterized protein conserved in bacteria:5-carboxymethyl-2-hydroxymuconate isomerase:Uncharacterized conserved protein:Predicted nucleotidyltransferase:Transposase and inactivated derivatives:Uncharacterized protein conserved in bacteria:2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase:2-keto-4-pentenoate hydratase:Amino acid transport and metabolism:Nucleotide transport and metabolism:Carbohydrate transport and metabolism:Lipid transport and metabolism:Transcription:Replication, recombination and repair:Cell wall/membrane/envelope biogenesis:Posttranslational modification, protein turnover, chaperones:Fatty acid metabolism:Valine leucine and isoleucine degradation:Tyrosine metabolism:Benzoate degradation:beta-Alanine metabolism:Propanoate metabolism:Aminoacyl-tRNA biosynthesis:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:Function unknown:Signal transduction mechanisms:HpaA:HpaD_Fe:HpaE:HpaG-C-term:HpaI:HpaH:phn_lysR:Translation:Genetic Information Processing:Xenobiotics Biodegradation and Metabolism:Metabolism of Other Amino Acids:Amino Acid Metabolism:Lipid Metabolism:Metabolism:Carbohydrate Metabolism:Poorly characterized:Metabolism:Cellular processes and signaling:Information storage and processing:Metabolism:Global" 158 "Energy production and conversion:ABC-type phosphate transport system, periplasmic component:Putative translation initiation inhibitor, yjgF family:Type II secretory pathway, component PulD:Type II secretory pathway, component PulF:Arginine/lysine/ornithine decarboxylases:Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases:Type II secretory pathway, ATPase PulE/Tfp pilus assembly pathway, ATPase PilB:Hemolysin activation/secretion protein:P pilus assembly protein, chaperone PapD:ABC-type branched-chain amino acid transport system, permease component:Amino acid transport and metabolism:Translation, ribosomal structure and biogenesis:Cell motility:Inorganic ion transport and metabolism:ABC transporters:Bacterial secretion system:type_II_gspD:type_II_gspE:urea_trans_UrtC:LLM_DMSO2_sfnG:Intracellular trafficking, secretion, and vesicular transport:Cellular processes and signaling:Membrane Transport:Central intermediary metabolism:Sulfur metabolism:Protein fate:Protein and peptide secretion and trafficking:Transport and binding proteins:Amino acids, peptides and amines:Cellular processes:Pathogenesis:Information storage and processing:Environmental Information Processing:Metabolism" 159 "Short-chain dehydrogenases of various substrate specificities:Uncharacterized NAD(FAD)-dependent dehydrogenases:Enoyl-CoA hydratase/carnithine racemase:Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor):FOG: GGDEF domain:Regulator of competence-specific genes:Response regulator containing a CheY-like receiver domain and an HD-GYP domain:Trans-aconitate methyltransferase:Flp pilus assembly protein, protease CpaA:Flp pilus assembly protein TadG:Lipid transport and metabolism:Transcription:Posttranslational modification, protein turnover, chaperones:Fatty acid metabolism:Valine leucine and isoleucine degradation:Geraniol degradation:Lysine degradation:Benzoate degradation:Tryptophan metabolism:beta-Alanine metabolism:Aminobenzoate degradation:Propanoate metabolism:Butanoate metabolism:Limonene and pinene degradation:Caprolactam degradation:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:General function prediction only:Signal transduction mechanisms:GGDEF:Intracellular trafficking, secretion, and vesicular transport:Other:Signal transduction:Metabolism:Metabolism:Global:Xenobiotics Biodegradation and Metabolism:Metabolism of Terpenoids and Polyketides:Metabolism of Other Amino Acids:Amino Acid Metabolism:Lipid Metabolism:Cellular processes and signaling:Carbohydrate Metabolism:Metabolism:Poorly characterized:Information storage and processing" 160 "Histidyl-tRNA synthetase:Cystathionine beta-lyases/cystathionine gamma-synthases:Parvulin-like peptidyl-prolyl isomerase:Enzyme involved in the deoxyxylulose pathway of isoprenoid biosynthesis:A/G-specific DNA glycosylase:Pyridoxal phosphate biosynthesis protein:Predicted deacylase:ABC-type arginine/histidine transport system, permease component:ABC-type histidine transport system, ATPase component:Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain:Amino acid transport and metabolism:Coenzyme transport and metabolism:Lipid transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:Replication, recombination and repair:Posttranslational modification, protein turnover, chaperones:Cysteine and methionine metabolism:Vitamin B6 metabolism:Terpenoid backbone biosynthesis:Aminoacyl-tRNA biosynthesis:Metabolic pathways:Biosynthesis of secondary metabolites:ABC transporters:Base excision repair:General function prediction only:hisS:pdxA:ispG_gcpE:mutY:O_suc_HS_sulf:HEQRo_perm_3TM:Information storage and processing:Amino Acid Metabolism:Metabolism of Cofactors and Vitamins:Metabolism of Terpenoids and Polyketides:Genetic Information Processing:Translation:Replication and Repair:Environmental Information Processing:Membrane Transport:Global:Metabolism:DNA metabolism:DNA replication, recombination, and repair:Protein synthesis:tRNA aminoacylation:Transport and binding proteins:Amino acids, peptides and amines:Amino acid biosynthesis:Aspartate family:Biosynthesis of cofactors, prosthetic groups, and carriers:Other:Pyridoxine:Metabolism:Cellular processes and signaling:Metabolism:Poorly characterized" 161 "NhaP-type Na+/H+ and K+/H+ antiporters:Predicted integral membrane protein:Protease subunit of ATP-dependent Clp proteases:Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases):Uncharacterized membrane protein:Phosphatidylserine/phosphatidylglycerophosphate/cardiolipin synthases and related enzymes:Uncharacterized protein (competence- and mitomycin-induced):ATP-dependent DNA ligase:Uncharacterized conserved protein:Uncharacterized conserved protein:Methylase of polypeptide chain release factors:Metal-dependent hydrolase:Lipid transport and metabolism:Translation, ribosomal structure and biogenesis:Replication, recombination and repair:Posttranslational modification, protein turnover, chaperones:Inorganic ion transport and metabolism:Glycerophospholipid metabolism:Metabolic pathways:Base excision repair:Nucleotide excision repair:Mismatch repair:Non-homologous end-joining:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:Function unknown:cinA_cterm:gshA_cyan_rel:NHEJ_ligase_prk:Intracellular trafficking, secretion, and vesicular transport:Lipid Metabolism:Cellular processes and signaling:Metabolism:Poorly characterized:DNA replication, recombination, and repair:DNA metabolism:Metabolism:Metabolism:Global:Replication and Repair:Genetic Information Processing:Information storage and processing" 162 "Pyridoxamine-phosphate oxidase:Fe2+ transport system protein B:Di- and tricarboxylate transporters:Cation transport ATPase:cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases:NAD-dependent protein deacetylases, SIR2 family:Predicted transcriptional regulators:Transcriptional regulators:Fe2+ transport system protein A:Bacterioferritin (cytochrome b1):Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain:Predicted carboxypeptidase:Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains:Sugar diacid utilization regulator:Signal transduction histidine kinase, nitrate/nitrite-specific:Predicted phosphoadenosine phosphosulfate sulfotransferase:Predicted ferric reductase:Amino acid transport and metabolism:Coenzyme transport and metabolism:Transcription:Inorganic ion transport and metabolism:Amino sugar and nucleotide sugar metabolism:Vitamin B6 metabolism:Metabolic pathways:Two-component system:General function prediction only:Signal transduction mechanisms:feoB:pdxH:bfr:ATPase_P-type:Information storage and processing:Pyridoxine:Biosynthesis of cofactors, prosthetic groups, and carriers:Cations and iron carrying compounds:Transport and binding proteins:Cellular processes and signaling:Metabolism:Metabolism:Poorly characterized:Metabolism:Global:Signal Transduction:Environmental Information Processing:Metabolism of Cofactors and Vitamins:Carbohydrate Metabolism" 163 "Adenylosuccinate lyase:Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II:Predicted Na+-dependent transporter:Cytosine deaminase and related metal-dependent hydrolases:Glutathione S-transferase:Enoyl-CoA hydratase/carnithine racemase:Transcriptional regulator:Outer membrane receptor proteins, mostly Fe transport:Uncharacterized membrane protein:Acyl-CoA dehydrogenases:Uncharacterized protein, possibly involved in aromatic compounds catabolism:FOG: GGDEF domain:Uncharacterized protein conserved in bacteria:Transcriptional activator of acetoin/glycerol metabolism:Predicted dioxygenase of extradiol dioxygenase family:Uncharacterized conserved protein:Xanthine dehydrogenase, iron-sulfur cluster and FAD-binding subunit A:Nucleotide transport and metabolism:Lipid transport and metabolism:Transcription:Posttranslational modification, protein turnover, chaperones:Inorganic ion transport and metabolism:Fatty acid metabolism:Purine metabolism:Valine leucine and isoleucine degradation:Geraniol degradation:Lysine degradation:Benzoate degradation:Tryptophan metabolism:beta-Alanine metabolism:Aminobenzoate degradation:Propanoate metabolism:Butanoate metabolism:Limonene and pinene degradation:Caprolactam degradation:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:Function unknown:Signal transduction mechanisms:sensory_box:GGDEF:unchar_dom_1:TonB-siderophor:protocat_pcaB:xanthine_xdhA:guan_deamin:Amino Acid Metabolism:Nucleotide Metabolism:Lipid Metabolism:Carbohydrate Metabolism:Energy metabolism:Other:Purines, pyrimidines, nucleosides, and nucleotides:Other:Regulatory functions:Small molecule interactions:Transport and binding proteins:Porins:Signal transduction:Other:Information storage and processing:Cellular processes and signaling:Metabolism:Poorly characterized:Metabolism:Global:Metabolism:Xenobiotics Biodegradation and Metabolism:Metabolism of Terpenoids and Polyketides:Metabolism of Other Amino Acids" 164 "Energy production and conversion:Anthranilate/para-aminobenzoate synthases component I:3-oxoacyl-[acyl-carrier-protein] synthase III:Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases:Zn-dependent hydrolases, including glyoxylases:Anthranilate/para-aminobenzoate synthases component II:Transcriptional regulator:2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases:Spermidine/putrescine-binding periplasmic protein:AraC-type DNA-binding domain-containing proteins:DNA-binding HTH domain-containing proteins:N-acyl-L-homoserine lactone synthetase:Uncharacterized conserved protein:Amino acid transport and metabolism:Coenzyme transport and metabolism:Lipid transport and metabolism:Transcription:Fatty acid biosynthesis:Phenylalanine tyrosine and tryptophan biosynthesis:Metabolic pathways:Biosynthesis of secondary metabolites:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:Function unknown:Signal transduction mechanisms:trpE_proteo:trpG_papA:Metabolism:Cellular processes and signaling:Metabolism:Poorly characterized:Aromatic amino acid family:Amino acid biosynthesis:Metabolism:Global:Amino Acid Metabolism:Lipid Metabolism:Information storage and processing" 165 "Energy production and conversion:Purine nucleoside phosphorylase:Aspartate oxidase:Imidazoleglycerol-phosphate dehydratase:1-acyl-sn-glycerol-3-phosphate acyltransferase:Glycerol-3-phosphate dehydrogenase:3-oxoacyl-[acyl-carrier-protein] synthase III:Quinolinate synthase:Carbonic anhydrases/acetyltransferases, isoleucine patch superfamily:Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog):CMP-2-keto-3-deoxyoctulosonic acid synthetase:Beta-glucosidase-related glycosidases:Transcriptional regulators:Adenosine deaminase:Ribosomal protein L11 methylase:Uncharacterized conserved protein:Cytochrome c553:Uncharacterized protein conserved in bacteria:Uncharacterized protein conserved in bacteria:Uncharacterized protein conserved in bacteria:Uncharacterized protein conserved in archaea:Amino acid transport and metabolism:Nucleotide transport and metabolism:Carbohydrate transport and metabolism:Coenzyme transport and metabolism:Lipid transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:Cell wall/membrane/envelope biogenesis:Posttranslational modification, protein turnover, chaperones:Fatty acid biosynthesis:Alanine aspartate and glutamate metabolism:Cysteine and methionine metabolism:Histidine metabolism:Amino sugar and nucleotide sugar metabolism:Lipopolysaccharide biosynthesis:Glycerophospholipid metabolism:Nicotinate and nicotinamide metabolism:Metabolic pathways:Biosynthesis of secondary metabolites:General function prediction only:Function unknown:prmA:kdsB:nadA:nadB:ogt:MTAP:lipid_A_lpxH:DNA replication, recombination, and repair:DNA metabolism:Salvage of nucleosides and nucleotides:Purines, pyrimidines, nucleosides, and nucleotides:Metabolism:Metabolism:Global:Metabolism of Cofactors and Vitamins:Glycan Biosynthesis and Metabolism:Amino Acid Metabolism:Lipid Metabolism:Poorly characterized:Carbohydrate Metabolism:Metabolism:Cellular processes and signaling:Information storage and processing:Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides:Cell envelope:Pyridine nucleotides:Biosynthesis of cofactors, prosthetic groups, and carriers:Ribosomal proteins: synthesis and modification:Protein synthesis" 166 "Energy production and conversion:Glutathione peroxidase:Na+/H+-dicarboxylate symporters:FOG: GGDEF domain:DNA-binding HTH domain-containing proteins:Membrane-bound lytic murein transglycosylase B:Plasmid maintenance system antidote protein:Uncharacterized protein conserved in bacteria:Uncharacterized protein conserved in bacteria:Uncharacterized conserved small protein:Transcription:Cell wall/membrane/envelope biogenesis:Posttranslational modification, protein turnover, chaperones:Glutathione metabolism:Arachidonic acid metabolism:Two-component system:General function prediction only:Function unknown:Signal transduction mechanisms:sensory_box:PHA_granule_1:MltB:antidote_HigA:Information storage and processing:Lipid Metabolism:Metabolism of Other Amino Acids:Environmental Information Processing:Signal Transduction:Fatty acid and phospholipid metabolism:Biosynthesis:Regulatory functions:Small molecule interactions:Mobile and extrachromosomal element functions:Other:Cell envelope:Biosynthesis and degradation of murein sacculus and peptidoglycan:Metabolism:Cellular processes and signaling:Metabolism:Poorly characterized" 167 "Energy production and conversion:Delta-aminolevulinic acid dehydratase:Glutamine synthetase:Acetate kinase:Polyferredoxin:Methyl-accepting chemotaxis protein:Polyphosphate kinase:BioD-like N-terminal domain of phosphotransacetylase:Predicted signal transduction protein:Predicted P-loop-containing kinase:Phosphotransferase system mannitol/fructose-specific IIA domain (Ntr-type):Pyrimidine operon attenuation protein/uracil phosphoribosyltransferase:Putative homoserine kinase type II (protein kinase fold):Uncharacterized protein conserved in bacteria:Amino acid transport and metabolism:Nucleotide transport and metabolism:Carbohydrate transport and metabolism:Coenzyme transport and metabolism:Cell motility:Inorganic ion transport and metabolism:Oxidative phosphorylation:Pyrimidine metabolism:Alanine aspartate and glutamate metabolism:Glycine serine and threonine metabolism:Arginine and proline metabolism:Taurine and hypotaurine metabolism:Pyruvate metabolism:Propanoate metabolism:Methane metabolism:Carbon fixation pathways in prokaryotes:Porphyrin and chlorophyll metabolism:Nitrogen metabolism:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:Two-component system:Bacterial chemotaxis:Phosphotransferase system (PTS):RNA degradation:General function prediction only:Function unknown:Signal transduction mechanisms:ackA:sensory_box:pta:GlnA:thrB_alt:nitro_reg_IIA:ccoG_rdxA_fixG:poly_P_kin:Aspartate family:Carbohydrate Metabolism:Energy Metabolism:Nucleotide Metabolism:Amino Acid Metabolism:Metabolism of Other Amino Acids:Metabolism of Cofactors and Vitamins:Genetic Information Processing:Folding Sorting and Degradation:Environmental Information Processing:Membrane Transport:Signal Transduction:Cellular Processes:Cell Motility:Global:Metabolism:Central intermediary metabolism:Phosphorus compounds:Energy metabolism:Fermentation:Regulatory functions:Small molecule interactions:Amino acid biosynthesis:Metabolism:Glutamate family:Signal transduction:PTS:Cellular processes and signaling:Metabolism:Poorly characterized" 168 "Type I restriction-modification system methyltransferase subunit:Type I site-specific restriction-modification system, R (restriction) subunit and related helicases:Predicted GTPases (dynamin-related):Restriction endonuclease S subunits:Type II secretory pathway, component PulF:Protein-disulfide isomerase:Type II secretory pathway, ATPase PulE/Tfp pilus assembly pathway, ATPase PilB:Transposase and inactivated derivatives:Tfp pilus assembly protein, tip-associated adhesin PilY1:Predicted ATP-dependent endonuclease of the OLD family:Predicted transcriptional regulator:Tfp pilus assembly protein PilX:Tfp pilus assembly protein PilW:Tfp pilus assembly protein PilV:Tfp pilus assembly protein PilE:Tfp pilus assembly protein, major pilin PilA:Tfp pilus assembly protein FimT:Transcription:Replication, recombination and repair:Cell motility:Posttranslational modification, protein turnover, chaperones:Aminoacyl-tRNA biosynthesis:Two-component system:General function prediction only:type_IV_pilV:IV_pilin_GFxxxE:type_IV_pilB:Intracellular trafficking, secretion, and vesicular transport:Defense mechanisms:Poorly characterized:Cellular processes and signaling:Information storage and processing:Protein modification and repair:Protein and peptide secretion and trafficking:Protein fate:Signal Transduction:Environmental Information Processing:Genetic Information Processing:Translation" 169 "Predicted membrane protein:Predicted signal transduction protein with a C-terminal ATPase domain:Response regulator of the LytR/AlgR family:Uncharacterized conserved protein:Uncharacterized protein conserved in archaea:Uncharacterized conserved protein:Transcription:Posttranslational modification, protein turnover, chaperones:Two-component system:Function unknown:Signal transduction mechanisms:Information storage and processing:Environmental Information Processing:Signal Transduction:Poorly characterized:Cellular processes and signaling" 170 "Energy production and conversion:Formamidopyrimidine-DNA glycosylase:Predicted Na+-dependent transporter:Aspartate/tyrosine/aromatic aminotransferase:Nucleoside-diphosphate-sugar epimerases:Superfamily II DNA and RNA helicases:Transcriptional regulator:Uncharacterized membrane-associated protein:FOG: TPR repeat, SEL1 subfamily:Diacylglycerol kinase:ABC-type amino acid transport/signal transduction systems, periplasmic component/domain:Methyl-accepting chemotaxis protein:Lactate dehydrogenase and related dehydrogenases:Predicted signal transduction protein:Threonine aldolase:3-methyladenine DNA glycosylase:Predicted acyltransferase:AraC-type DNA-binding domain-containing proteins:Uncharacterized protein conserved in bacteria:Uncharacterized protein conserved in bacteria:Predicted membrane protein:Predicted membrane protein:Cytochrome c556:Predicted aminopeptidase:Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain:Amino acid transport and metabolism:Carbohydrate transport and metabolism:Coenzyme transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:Replication, recombination and repair:Cell wall/membrane/envelope biogenesis:Cell motility:Glycine serine and threonine metabolism:Phenylalanine tyrosine and tryptophan biosynthesis:Glycerolipid metabolism:Glycerophospholipid metabolism:Glyoxylate and dicarboxylate metabolism:Methane metabolism:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:Two-component system:Bacterial chemotaxis:Base excision repair:General function prediction only:Function unknown:Signal transduction mechanisms:GGDEF:fpg:PHA_gran_rgn:Carbohydrate Metabolism:Signal transduction:Other:Information storage and processing:Cellular processes and signaling:Metabolism:Poorly characterized:Metabolism:DNA metabolism:Metabolism:Global:Cell Motility:Cellular Processes:Signal Transduction:Environmental Information Processing:Replication and Repair:Genetic Information Processing:Amino Acid Metabolism:Lipid Metabolism:Energy Metabolism:DNA replication, recombination, and repair" 171 "Lactoylglutathione lyase and related lyases:Uncharacterized conserved protein:Transcriptional regulator:Signal transduction histidine kinase:3-hydroxyacyl-CoA dehydrogenase:Amidases related to nicotinamidase:Outer membrane protein:Uncharacterized protein, possibly involved in aromatic compounds catabolism:ABC-type proline/glycine betaine transport systems, periplasmic components:Aromatic ring hydroxylase:PEP phosphonomutase and related enzymes:DNA-binding HTH domain-containing proteins:Uncharacterized iron-regulated membrane protein:Uncharacterized protein conserved in bacteria:Nucleoside 2-deoxyribosyltransferase:ABC-type phosphate/phosphonate transport system, permease component:Amino acid transport and metabolism:Nucleotide transport and metabolism:Carbohydrate transport and metabolism:Lipid transport and metabolism:Transcription:Cell wall/membrane/envelope biogenesis:Inorganic ion transport and metabolism:Tyrosine metabolism:Benzoate degradation:Butanoate metabolism:Biosynthesis of siderophore group nonribosomal peptides:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:ABC transporters:Secondary metabolites biosynthesis, transport and catabolism:Function unknown:Signal transduction mechanisms:unchar_dom_1:PhnE:type_I_hlyD:type_I_sec_TolC:HpaB-2:Intracellular trafficking, secretion, and vesicular transport:Metabolism:Carbohydrate Metabolism:Amino Acid Metabolism:Metabolism of Terpenoids and Polyketides:Xenobiotics Biodegradation and Metabolism:Environmental Information Processing:Membrane Transport:Global:Metabolism:Protein fate:Protein and peptide secretion and trafficking:Transport and binding proteins:Anions:Porins:Information storage and processing:Cellular processes and signaling:Metabolism:Poorly characterized" 172 "Chromatin structure and dynamics:Energy production and conversion:Deacetylases, including yeast histone deacetylase and acetoin utilization protein:Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily):Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases):Transcriptional regulators:Predicted membrane-associated, metal-dependent hydrolase:AraC-type DNA-binding domain-containing proteins:Sugar phosphate permease:Arabinose efflux permease:Hemolysin activation/secretion protein:Na+-transporting NADH:ubiquinone oxidoreductase, subunit NqrF:Phospholipase C:Phenylpropionate dioxygenase and related ring-hydroxylating dioxygenases, large terminal subunit:L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily:Small subunit of phenylpropionate dioxygenase:Carbohydrate transport and metabolism:Lipid transport and metabolism:Transcription:Cell wall/membrane/envelope biogenesis:Inorganic ion transport and metabolism:Chlorocyclohexane and chlorobenzene degradation:Benzoate degradation:Fluorobenzoate degradation:Inositol phosphate metabolism:Glycerophospholipid metabolism:Ether lipid metabolism:Xylene degradation:Toluene degradation:Metabolic pathways:Microbial metabolism in diverse environments:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:protocat_pcaD:mucon_cyclo:benzo_1_2_benA:benzo_1_2_benB:PC_PLC:plc_access_R:Intracellular trafficking, secretion, and vesicular transport:Metabolism:Poorly characterized:Metabolism:Cellular processes and signaling:Information storage and processing:Pathogenesis:Cellular processes:Other:Energy metabolism:Metabolism:Global:Xenobiotics Biodegradation and Metabolism:Lipid Metabolism:Carbohydrate Metabolism" 173 "Arginase/agmatinase/formimionoglutamate hydrolase, arginase family:Sulfite reductase, alpha subunit (flavoprotein):Transcriptional regulator:Cation/multidrug efflux pump:Membrane-fusion protein:Enoyl-CoA hydratase/carnithine racemase:Predicted membrane protein:Transcriptional regulator:Transcriptional regulator:Predicted transcriptional regulators:Outer membrane protein:Outer membrane receptor proteins, mostly Fe transport:Esterase/lipase:Site-specific recombinases, DNA invertase Pin homologs:Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain:Predicted membrane protein:Transposase and inactivated derivatives:Predicted hydrolase of alkaline phosphatase superfamily:Uncharacterized conserved protein:Sigma54-dependent transcription regulator containing an AAA-type ATPase domain and a DNA-binding domain:Predicted alpha/beta hydrolase:Amino acid transport and metabolism:Lipid transport and metabolism:Transcription:Replication, recombination and repair:Cell wall/membrane/envelope biogenesis:Inorganic ion transport and metabolism:Fatty acid metabolism:Valine leucine and isoleucine degradation:Geraniol degradation:Lysine degradation:Histidine metabolism:Benzoate degradation:Tryptophan metabolism:beta-Alanine metabolism:Aminobenzoate degradation:Propanoate metabolism:Butanoate metabolism:Limonene and pinene degradation:Sulfur metabolism:Caprolactam degradation:Aminoacyl-tRNA biosynthesis:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:Two-component system:General function prediction only:Function unknown:Signal transduction mechanisms:2A0602:hutG:RND_mfp:outer_NodT:Intracellular trafficking, secretion, and vesicular transport:Defense mechanisms:Metabolism:Poorly characterized:Metabolism:Cellular processes and signaling:Information storage and processing:Porins:Unknown substrate:Transport and binding proteins:Amino acids and amines:Energy metabolism:Metabolism:Global:Signal Transduction:Environmental Information Processing:Translation:Genetic Information Processing:Xenobiotics Biodegradation and Metabolism:Metabolism of Terpenoids and Polyketides:Metabolism of Other Amino Acids:Amino Acid Metabolism:Lipid Metabolism:Energy Metabolism:Carbohydrate Metabolism" 174 "Phenylalanyl-tRNA synthetase beta subunit:Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase:5-enolpyruvylshikimate-3-phosphate synthase:tRNA and rRNA cytosine-C5-methylases:Cysteinyl-tRNA synthetase:Methionyl-tRNA formyltransferase:Predicted redox protein, regulator of disulfide bond formation:Predicted phosphatases:K+ transport systems, NAD-binding component:DNA polymerase I - 3'-5' exonuclease and polymerase domains:dUTPase:Predicted carbamoyl transferase, NodU family:Predicted molecular chaperone distantly related to HSP70-fold metalloproteases:Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain:Amino acid transport and metabolism:Nucleotide transport and metabolism:Translation, ribosomal structure and biogenesis:Replication, recombination and repair:Posttranslational modification, protein turnover, chaperones:Inorganic ion transport and metabolism:Purine metabolism:Pyrimidine metabolism:Histidine metabolism:Tyrosine metabolism:Phenylalanine metabolism:Phenylalanine tyrosine and tryptophan biosynthesis:Novobiocin biosynthesis:Glyoxylate and dicarboxylate metabolism:One carbon pool by folate:Aminoacyl-tRNA biosynthesis:Metabolic pathways:Biosynthesis of secondary metabolites:DNA replication:Base excision repair:Nucleotide excision repair:Homologous recombination:General function prediction only:Signal transduction mechanisms:sensory_box:cysS:fmt:pheT_bact:rsmB:dut:pola:hisC:aroA:Aromatic amino acid family:Carbohydrate Metabolism:Nucleotide Metabolism:Amino Acid Metabolism:Metabolism of Cofactors and Vitamins:Biosynthesis of Other Secondary Metabolites:Genetic Information Processing:Translation:Replication and Repair:Global:Metabolism:Purines, pyrimidines, nucleosides, and nucleotides:2'-Deoxyribonucleotide metabolism:Regulatory functions:Small molecule interactions:DNA metabolism:DNA replication, recombination, and repair:Protein synthesis:tRNA aminoacylation:tRNA and rRNA base modification:Amino acid biosynthesis:Metabolism:Histidine family:Information storage and processing:Cellular processes and signaling:Metabolism:Poorly characterized" 175 "Energy production and conversion:Dihydrodipicolinate synthase/N-acetylneuraminate lyase:Cytosine deaminase and related metal-dependent hydrolases:Amino acid transporters:Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases:Transcriptional regulator:Signal transduction histidine kinase:Aldo/keto reductases, related to diketogulonate reductase:ABC-type amino acid transport/signal transduction systems, periplasmic component/domain:Methyl-accepting chemotaxis protein:Membrane-fusion protein:ABC-type multidrug transport system, ATPase and permease components:Amidases related to nicotinamidase:Predicted acyl-CoA transferases/carnitine dehydratase:NADH:flavin oxidoreductases, Old Yellow Enzyme family:Adenosine deaminase:AraC-type DNA-binding domain-containing proteins:Arabinose efflux permease:Na+/H+ antiporter:Large exoproteins involved in heme utilization or adhesion:Hydroxypyruvate isomerase:Outer membrane receptor for ferrienterochelin and colicins:Predicted permease, DMT superfamily:Amino acid transport and metabolism:Nucleotide transport and metabolism:Carbohydrate transport and metabolism:Transcription:Cell wall/membrane/envelope biogenesis:Cell motility:Inorganic ion transport and metabolism:Lysine biosynthesis:Glyoxylate and dicarboxylate metabolism:Nitrotoluene degradation:Methane metabolism:Atrazine degradation:Biosynthesis of siderophore group nonribosomal peptides:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:Two-component system:Bacterial chemotaxis:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:Signal transduction mechanisms:sensory_box:2A0106:RND_mfp:TonB-siderophor:adhes_NPXG:MsbA_rel:Intracellular trafficking, secretion, and vesicular transport:Defense mechanisms:Cellular processes and signaling:Information storage and processing:Porins:Unknown substrate:Transport and binding proteins:Small molecule interactions:Regulatory functions:Metabolism:Metabolism:Global:Cell Motility:Cellular Processes:Signal Transduction:Environmental Information Processing:Xenobiotics Biodegradation and Metabolism:Metabolism of Terpenoids and Polyketides:Amino Acid Metabolism:Energy Metabolism:Carbohydrate Metabolism:Poorly characterized:Metabolism" 176 "Putative translation initiation inhibitor, yjgF family:Short-chain dehydrogenases of various substrate specificities:ABC-type nitrate/sulfonate/bicarbonate transport system, permease component:ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components:Methyl-accepting chemotaxis protein:Non-ribosomal peptide synthetase modules and related proteins:Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases):ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component:Uncharacterized conserved protein:Predicted metal-dependent hydrolase with the TIM-barrel fold:Uncharacterized conserved protein, contains double-stranded beta-helix domain:Acyl-CoA dehydrogenases:Uncharacterized conserved protein:Uncharacterized Fe-S protein:Chitinase:Streptogramin lyase:Carbohydrate transport and metabolism:Lipid transport and metabolism:Translation, ribosomal structure and biogenesis:Cell motility:Inorganic ion transport and metabolism:ABC transporters:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:Function unknown:Signal transduction mechanisms:ahpD_dom:AA-adenyl-dom:Defense mechanisms:General:Unknown function:Membrane Transport:Environmental Information Processing:Poorly characterized:Metabolism:Cellular processes and signaling:Information storage and processing" 177 "Energy production and conversion:Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit:Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily):Predicted permeases:Predicted thioesterase:Flavodoxin reductases (ferredoxin-NADPH reductases) family 1:Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases):Threonine dehydrogenase and related Zn-dependent dehydrogenases:Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit:Outer membrane protein:Predicted flavoprotein involved in K+ transport:Nitrate/nitrite transporter:Uncharacterized conserved protein:ABC-type uncharacterized transport system, permease component:Phenylpropionate dioxygenase and related ring-hydroxylating dioxygenases, large terminal subunit:Uncharacterized ABC-type transport system, ATPase component:Amino acid transport and metabolism:Lipid transport and metabolism:Cell wall/membrane/envelope biogenesis:Inorganic ion transport and metabolism:Glycolysis / Gluconeogenesis:Citrate cycle (TCA cycle):Valine leucine and isoleucine biosynthesis:Pyruvate metabolism:Aminobenzoate degradation:Butanoate metabolism:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:ABC transporters:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:Function unknown:efflux_EmrB:2A0108:outer_NodT:urea_trans_UrtD:Intracellular trafficking, secretion, and vesicular transport:Poorly characterized:Metabolism:Cellular processes and signaling:Porins:Other:Anions:Amino acids, peptides and amines:Transport and binding proteins:Metabolism:Metabolism:Global:Membrane Transport:Environmental Information Processing:Xenobiotics Biodegradation and Metabolism:Amino Acid Metabolism:Carbohydrate Metabolism" 178 "Geranylgeranyl pyrophosphate synthase:GTP cyclohydrolase I:Phosphopantetheine adenylyltransferase:Predicted permeases:Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain:Transcription elongation factor:2-keto-3-deoxy-6-phosphogluconate aldolase:Acetyl-CoA carboxylase alpha subunit:Septum formation inhibitor:Septum formation topological specificity factor:ABC-type transport system involved in resistance to organic solvents, ATPase component:Transcriptional regulator:Chorismate mutase:Exonuclease VII small subunit:Preprotein translocase subunit YajC:Predicted acyltransferase:DNA polymerase III, gamma/tau subunits:Uncharacterized protein conserved in bacteria:Cell cycle control, cell division, chromosome partitioning:Amino acid transport and metabolism:Carbohydrate transport and metabolism:Coenzyme transport and metabolism:Lipid transport and metabolism:Transcription:Replication, recombination and repair:Pentose phosphate pathway:Pentose and glucuronate interconversions:Fatty acid biosynthesis:Purine metabolism:Pyrimidine metabolism:Arginine and proline metabolism:Phenylalanine tyrosine and tryptophan biosynthesis:Pyruvate metabolism:Glyoxylate and dicarboxylate metabolism:Propanoate metabolism:Carbon fixation pathways in prokaryotes:Pantothenate and CoA biosynthesis:Folate biosynthesis:Terpenoid backbone biosynthesis:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:DNA replication:Protein export:Bacterial secretion system:Mismatch repair:Homologous recombination:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:Function unknown:Signal transduction mechanisms:folE:cyt_tran_rel:accA:yajC:eda:minE:minC:xseB:CM_mono2:dnaX_nterm:Intracellular trafficking, secretion, and vesicular transport:Metabolism:Poorly characterized:Metabolism:Global:Membrane Transport:Environmental Information Processing:Replication and Repair:Metabolism:Folding Sorting and Degradation:Genetic Information Processing:Metabolism of Terpenoids and Polyketides:Metabolism of Cofactors and Vitamins:Amino Acid Metabolism:Nucleotide Metabolism:Lipid Metabolism:Energy Metabolism:Carbohydrate Metabolism:Energy metabolism:Entner-Doudoroff:Fatty acid and phospholipid metabolism:Biosynthesis:DNA metabolism:Degradation of DNA:DNA replication, recombination, and repair:Protein fate:Protein and peptide secretion and trafficking:Cellular processes:Cell division:Amino acid biosynthesis:Aromatic amino acid family:Biosynthesis of cofactors, prosthetic groups, and carriers:Folic acid:Information storage and processing:Cellular processes and signaling" 179 "Energy production and conversion:Glutamate-1-semialdehyde aminotransferase:Ribonucleotide reductase, beta subunit:Ribonucleotide reductase, alpha subunit:Predicted phosphatases:DNA polymerase III, epsilon subunit and related 3'-5' exonucleases:Aspartate ammonia-lyase:Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases):Aconitase B:dTDP-4-dehydrorhamnose reductase:dTDP-glucose pyrophosphorylase:dTDP-4-dehydrorhamnose 3,5-epimerase and related enzymes:Uncharacterized iron-regulated protein:Kynureninase:Acetyl/propionyl-CoA carboxylase, alpha subunit:Pyruvate/oxaloacetate carboxyltransferase:Amino acid transport and metabolism:Nucleotide transport and metabolism:Coenzyme transport and metabolism:Lipid transport and metabolism:Replication, recombination and repair:Cell wall/membrane/envelope biogenesis:Inorganic ion transport and metabolism:Citrate cycle (TCA cycle):Purine metabolism:Pyrimidine metabolism:Alanine aspartate and glutamate metabolism:Tryptophan metabolism:Streptomycin biosynthesis:Polyketide sugar unit biosynthesis:Pyruvate metabolism:Glyoxylate and dicarboxylate metabolism:Carbon fixation pathways in prokaryotes:Porphyrin and chlorophyll metabolism:Nitrogen metabolism:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:acnB:accC:hemL:aspA:oadA:rmlA:rmlD:rmlC:RNaseT:PGP_bact:kynureninase:NrdE_NrdA:Cell envelope:Carbohydrate Metabolism:Energy Metabolism:Nucleotide Metabolism:Amino Acid Metabolism:Metabolism of Cofactors and Vitamins:Metabolism of Terpenoids and Polyketides:Biosynthesis of Other Secondary Metabolites:Global:Metabolism:Energy metabolism:Amino acids and amines:TCA cycle:Other:Sugars:Fatty acid and phospholipid metabolism:Biosynthesis:Purines, pyrimidines, nucleosides, and nucleotides:2'-Deoxyribonucleotide metabolism:Transcription:RNA processing:Biosynthesis of cofactors, prosthetic groups, and carriers:Heme, porphyrin, and cobalamin:Metabolism:Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides:Information storage and processing:Cellular processes and signaling:Metabolism:Poorly characterized" 180 "Energy production and conversion:FAD/FMN-containing dehydrogenases:Glycosyltransferases involved in cell wall biogenesis:Pyruvate kinase:Predicted dehydrogenases and related proteins:Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases):Sugar phosphate isomerases/epimerases:L-serine deaminase:4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family:NADH:flavin oxidoreductases, Old Yellow Enzyme family:Malate/L-lactate dehydrogenases:Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain:Uncharacterized conserved protein:Uncharacterized protein conserved in bacteria:Amino acid transport and metabolism:Carbohydrate transport and metabolism:Lipid transport and metabolism:Transcription:Cell wall/membrane/envelope biogenesis:Glycolysis / Gluconeogenesis:Purine metabolism:Glycine serine and threonine metabolism:Cysteine and methionine metabolism:Pyruvate metabolism:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:Two-component system:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:Function unknown:Signal transduction mechanisms:sda_mono:pyruv_kin:bact_FAD_ox:Metabolism:Cellular processes and signaling:Information storage and processing:Glycolysis/gluconeogenesis:Energy metabolism:Metabolism:Metabolism:Global:Signal Transduction:Environmental Information Processing:Amino Acid Metabolism:Nucleotide Metabolism:Poorly characterized:Carbohydrate Metabolism" 181 "1-acyl-sn-glycerol-3-phosphate acyltransferase:Predicted rRNA methylase (SpoU class):L-asparaginase/archaeal Glu-tRNAGln amidotransferase subunit D:Phosphoserine phosphatase:Alanine racemase:Na+/alanine symporter:Disulfide bond formation protein DsbB:Dihydroneopterin aldolase:Lauroyl/myristoyl acyltransferase:Transcriptional regulators:Arabinose efflux permease:Uncharacterized protein conserved in bacteria:Uncharacterized protein conserved in bacteria:Uncharacterized conserved protein:Predicted Fe-S protein:Aspartyl/asparaginyl beta-hydroxylase and related dioxygenases:Uncharacterized conserved protein:Predicted soluble lytic transglycosylase fused to an ABC-type amino acid-binding protein:Uncharacterized protein conserved in bacteria:Amino acid transport and metabolism:Carbohydrate transport and metabolism:Coenzyme transport and metabolism:Lipid transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:Cell wall/membrane/envelope biogenesis:Posttranslational modification, protein turnover, chaperones:Alanine aspartate and glutamate metabolism:Glycine serine and threonine metabolism:Cyanoamino acid metabolism:D-Alanine metabolism:Lipopolysaccharide biosynthesis:Peptidoglycan biosynthesis:Methane metabolism:Folate biosynthesis:Nitrogen metabolism:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:General function prediction only:Function unknown:rRNA_methyl_2:serB:alr:folB:efflux_Bcr_CflA:agcS:mono_pep_trsgly:MJ0042_CXXC:lipid_A_htrB:Metabolism:Cellular processes and signaling:Information storage and processing:Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides:Biosynthesis and degradation of murein sacculus and peptidoglycan:Cell envelope:Folic acid:Biosynthesis of cofactors, prosthetic groups, and carriers:Serine family:Amino acid biosynthesis:tRNA and rRNA base modification:Protein synthesis:Metabolism:Metabolism:Global:Metabolism of Cofactors and Vitamins:Glycan Biosynthesis and Metabolism:Metabolism of Other Amino Acids:Amino Acid Metabolism:Poorly characterized:Energy Metabolism" 182 "Adenylosuccinate synthase:Translation initiation factor 3 (IF-3):Ribosomal protein L35:Membrane protease subunits, stomatin/prohibitin homologs:Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family:UDP-3-O-acyl-N-acetylglucosamine deacetylase:Bacterial nucleoid DNA-binding protein:ABC-type amino acid transport/signal transduction systems, periplasmic component/domain:Sec-independent protein secretion pathway components:Uncharacterized host factor I protein:Outer membrane protein and related peptidoglycan-associated (lipo)proteins:Outer membrane protein W:Amino acid transport and metabolism:Nucleotide transport and metabolism:Translation, ribosomal structure and biogenesis:Replication, recombination and repair:Cell wall/membrane/envelope biogenesis:Posttranslational modification, protein turnover, chaperones:Purine metabolism:Alanine aspartate and glutamate metabolism:Lipopolysaccharide biosynthesis:Aminoacyl-tRNA biosynthesis:Metabolic pathways:ABC transporters:Ribosome:RNA degradation:Protein export:Bacterial secretion system:General function prediction only:Signal transduction mechanisms:rpmI_bact:infC:purA:lpxC:3A0103s03R:tatB:tatAE:hflC:hflK:Hfq:Pal_lipo:Intracellular trafficking, secretion, and vesicular transport:Amino acids, peptides and amines:Nucleotide Metabolism:Amino Acid Metabolism:Glycan Biosynthesis and Metabolism:Genetic Information Processing:Translation:Folding Sorting and Degradation:Environmental Information Processing:Membrane Transport:Global:Metabolism:Purines, pyrimidines, nucleosides, and nucleotides:Purine ribonucleotide biosynthesis:Regulatory functions:Other:Protein interactions:Protein synthesis:Ribosomal proteins: synthesis and modification:Translation factors:Protein fate:Protein and peptide secretion and trafficking:Transport and binding proteins:Metabolism:Cell envelope:Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides:Information storage and processing:Cellular processes and signaling:Metabolism:Poorly characterized" 183 "ATPases with chaperone activity, ATP-binding subunit:Non-ribosomal peptide synthetase modules and related proteins:Probable taurine catabolism dioxygenase:Hemolysin-coregulated protein (uncharacterized):Uncharacterized protein conserved in bacteria:Uncharacterized protein conserved in bacteria:Uncharacterized protein conserved in bacteria:Uncharacterized protein conserved in bacteria:Uncharacterized protein conserved in bacteria:Uncharacterized protein conserved in bacteria:Uncharacterized protein conserved in bacteria:Uncharacterized protein conserved in bacteria:Posttranslational modification, protein turnover, chaperones:Bacterial secretion system:Secondary metabolites biosynthesis, transport and catabolism:Function unknown:fkbM_fam:vgr_GE:AA-adenyl-dom:VI_ClpV1:VI_chp_1:VI_chp_4:VI_chp_2:VI_zyme:VI_chp_5:VI_chp_6:Metabolism:Membrane Transport:Cellular processes:Pathogenesis:Cellular processes and signaling:Environmental Information Processing:Poorly characterized" 184 "Flagellar biosynthesis/type III secretory pathway ATPase:Flagellar motor switch/type III secretory pathway protein:Type III secretory pathway, component EscV:Type III secretory pathway, component EscR:Type III secretory pathway, component EscS:NAD+--asparagine ADP-ribosyltransferase:Uncharacterized conserved protein:Cell motility:Bacterial secretion system:Function unknown:Signal transduction mechanisms:fliI_yscN:yscR:hrcV:fliQ_rel_III:type_III_YscX:type_III_SycN:type_III_tyeA:type_III_yscP:SpaO_YscQ:LcrH_SycD:LcrE:LcrG_PcrG:Intracellular trafficking, secretion, and vesicular transport:ATP-proton motive force interconversion:Membrane Transport:Energy metabolism:Environmental Information Processing:Cellular processes:Pathogenesis:Cellular processes and signaling:Poorly characterized" 185 "Energy production and conversion:Acetyl-CoA hydrolase:Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily):ABC-type amino acid transport/signal transduction systems, periplasmic component/domain:Predicted hydrolase (HAD superfamily):3-hydroxyacyl-CoA dehydrogenase:Acyl-CoA dehydrogenases:Acyl dehydratase:Predicted membrane protein:Regulator of polyketide synthase expression:Hemolysin activation/secretion protein:Poly(3-hydroxyalkanoate) synthetase:Uncharacterized conserved protein:Uncharacterized protein conserved in bacteria:Amino acid transport and metabolism:Lipid transport and metabolism:Fatty acid metabolism:Valine leucine and isoleucine degradation:Geraniol degradation:Lysine degradation:Chlorocyclohexane and chlorobenzene degradation:Benzoate degradation:Tryptophan metabolism:beta-Alanine metabolism:Chloroalkane and chloroalkene degradation:Propanoate metabolism:Butanoate metabolism:Carbon fixation pathways in prokaryotes:Limonene and pinene degradation:Caprolactam degradation:Biosynthesis of unsaturated fatty acids:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:Function unknown:Signal transduction mechanisms:HAD_type_II:PHA_granule_1:PHA_synth_II:PHA_depoly_arom:Intracellular trafficking, secretion, and vesicular transport:Carbohydrate Metabolism:Energy metabolism:Other:Fatty acid and phospholipid metabolism:Biosynthesis:Cellular processes and signaling:Metabolism:Poorly characterized:Global:Xenobiotics Biodegradation and Metabolism:Metabolism of Terpenoids and Polyketides:Metabolism:Metabolism of Other Amino Acids:Amino Acid Metabolism:Lipid Metabolism:Energy Metabolism:Metabolism" 186 "Energy production and conversion:Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase:Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase:Phosphoribosylaminoimidazolesuccinocarboxamide (SAICAR) synthase:Uncharacterized conserved protein:Inorganic pyrophosphatase:Dihydrodipicolinate synthase/N-acetylneuraminate lyase:Ribosomal protein S1:FKBP-type peptidyl-prolyl cis-trans isomerase (trigger factor):DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32):Phosphoglyceromutase:Peroxiredoxin:Organic solvent tolerance protein OstA:Uncharacterized lipoprotein:Amino acid transport and metabolism:Nucleotide transport and metabolism:Carbohydrate transport and metabolism:Coenzyme transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:Cell wall/membrane/envelope biogenesis:Posttranslational modification, protein turnover, chaperones:Glycolysis / Gluconeogenesis:Oxidative phosphorylation:Purine metabolism:Valine leucine and isoleucine degradation:Valine leucine and isoleucine biosynthesis:Lysine biosynthesis:Methane metabolism:Pantothenate and CoA biosynthesis:Aminoacyl-tRNA biosynthesis:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:Ribosome:RNA polymerase:Function unknown:purC:tig:dapA:rpsA:TIGR01033:ilvE_I:pgm_bpd_ind:GAPDH-I:RpoD_Cterm:Amino acid biosynthesis:Aspartate family:Pyruvate family:Information storage and processing:Cellular processes and signaling:Metabolism:Poorly characterized:Energy metabolism:Metabolism:Global:Metabolism:Translation:Transcription:Genetic Information Processing:Metabolism of Cofactors and Vitamins:Amino Acid Metabolism:Nucleotide Metabolism:Energy Metabolism:Glycolysis/gluconeogenesis:Carbohydrate Metabolism:Purines, pyrimidines, nucleosides, and nucleotides:Purine ribonucleotide biosynthesis:Regulatory functions:DNA interactions:Transcription:Transcription factors:Protein synthesis:Ribosomal proteins: synthesis and modification:Protein fate:Protein folding and stabilization" 187 "Energy production and conversion:Short-chain dehydrogenases of various substrate specificities:Nucleoside-diphosphate-sugar epimerases:Thioredoxin reductase:Transcriptional regulator:Na+/proline symporter:Predicted sugar phosphatases of the HAD superfamily:Molybdopterin-guanine dinucleotide biosynthesis protein A:Methyl-accepting chemotaxis protein:Lactate dehydrogenase and related dehydrogenases:Hemolysins and related proteins containing CBS domains:Transcriptional regulator:Acetyltransferases, including N-acetylases of ribosomal proteins:AraC-type DNA-binding domain-containing proteins:2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase:Uncharacterized protein with SCP/PR1 domains:Uncharacterized iron-regulated membrane protein:Uncharacterized protein conserved in bacteria:5-carboxymethyl-2-hydroxymuconate isomerase:Uncharacterized protein, possibly involved in glyoxylate utilization:Predicted enzyme of the cupin superfamily:Uncharacterized protein conserved in bacteria:Amino acid transport and metabolism:Carbohydrate transport and metabolism:Coenzyme transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:Cell wall/membrane/envelope biogenesis:Cell motility:Posttranslational modification, protein turnover, chaperones:Pyrimidine metabolism:Glycine serine and threonine metabolism:Tyrosine metabolism:Benzoate degradation:Glyoxylate and dicarboxylate metabolism:Methane metabolism:Metabolic pathways:Microbial metabolism in diverse environments:Two-component system:Bacterial chemotaxis:General function prediction only:Function unknown:Signal transduction mechanisms:TRX_reduct:HAD-SF-IIA-hyp4:molyb_mobA:ura-cupin:Poorly characterized:Metabolism:Cellular processes and signaling:Information storage and processing:Molybdopterin:Biosynthesis of cofactors, prosthetic groups, and carriers:Electron transport:Energy metabolism:Metabolism:Metabolism:Global:Cell Motility:Cellular Processes:Signal Transduction:Environmental Information Processing:Xenobiotics Biodegradation and Metabolism:Amino Acid Metabolism:Nucleotide Metabolism:Energy Metabolism:Carbohydrate Metabolism" 188 "Beta-lactamase class C and other penicillin binding proteins:AraC-type DNA-binding domain-containing proteins:Retron-type reverse transcriptase:Uncharacterized conserved protein:Transcription:Replication, recombination and repair:Function unknown:Defense mechanisms:Information storage and processing:Poorly characterized:Cellular processes and signaling" 189 "Energy production and conversion:Glutamate synthase domain 2:EMAP domain:3-methyladenine DNA glycosylase/8-oxoguanine DNA glycosylase:Short-chain dehydrogenases of various substrate specificities:Acetyl-CoA hydrolase:Zn-dependent hydrolases, including glyoxylases:NADPH-dependent glutamate synthase beta chain and related oxidoreductases:SAM-dependent methyltransferases:Gamma-aminobutyrate permease and related permeases:Transcriptional regulator:Predicted ATPase:Predicted redox protein, regulator of disulfide bond formation:Uncharacterized protein conserved in bacteria:Predicted permeases:Cytochrome B561:Uncharacterized protein conserved in bacteria:Predicted enzyme of the cupin superfamily:P pilus assembly/Cpx signaling pathway, periplasmic inhibitor/zinc-resistance associated protein:Signal transduction histidine kinase regulating C4-dicarboxylate transport system:Uncharacterized protein conserved in bacteria:Amino acid transport and metabolism:Transcription:Replication, recombination and repair:Cell motility:Posttranslational modification, protein turnover, chaperones:Inorganic ion transport and metabolism:Alanine aspartate and glutamate metabolism:Nitrogen metabolism:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:Base excision repair:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:Function unknown:Signal transduction mechanisms:sensory_box:gltD_gamma_fam:chap_CsaA:YgfH_subfam:organ_hyd_perox:Intracellular trafficking, secretion, and vesicular transport:Detoxification:Cellular processes:Protein and peptide secretion and trafficking:Protein fate:Small molecule interactions:Regulatory functions:Metabolism:Global:Replication and Repair:Genetic Information Processing:Amino Acid Metabolism:Energy Metabolism:Metabolism:Poorly characterized:Metabolism:Cellular processes and signaling:Information storage and processing" 190 "Energy production and conversion:Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase:Lactoylglutathione lyase and related lyases:Glucose-6-phosphate 1-dehydrogenase:SAM-dependent methyltransferases:Transcriptional regulator:NADPH:quinone reductase and related Zn-dependent oxidoreductases:Glutathione S-transferase:Predicted membrane metal-binding protein:Putative intracellular protease/amidase:Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases):Mg-chelatase subunit ChlD:Uncharacterized conserved protein:Cytochrome P450:FOG: GGDEF domain:Uncharacterized conserved protein:Uncharacterized protein conserved in bacteria:Uncharacterized protein conserved in bacteria:Uncharacterized protein conserved in bacteria:Predicted permease, DMT superfamily:Amino acid transport and metabolism:Carbohydrate transport and metabolism:Coenzyme transport and metabolism:Lipid transport and metabolism:Transcription:Posttranslational modification, protein turnover, chaperones:Pentose phosphate pathway:Histidine metabolism:Tyrosine metabolism:Phenylalanine metabolism:Bisphenol degradation:Phenylalanine tyrosine and tryptophan biosynthesis:Novobiocin biosynthesis:Glutathione metabolism:Pyruvate metabolism:Polycyclic aromatic hydrocarbon degradation:Aminobenzoate degradation:Limonene and pinene degradation:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:Function unknown:Signal transduction mechanisms:glyox_I:GGDEF:ComEC_N-term:zwf:Global:Metabolism:Xenobiotics Biodegradation and Metabolism:Biosynthesis of Other Secondary Metabolites:Metabolism of Terpenoids and Polyketides:Metabolism of Other Amino Acids:Amino Acid Metabolism:Metabolism:Carbohydrate Metabolism:Poorly characterized:Cellular processes and signaling:Information storage and processing:Other:Signal transduction:General:Unknown function:Other:Pentose phosphate pathway:Energy metabolism:Metabolism" 191 "Energy production and conversion:Cysteine synthase:Adenosylmethionine-8-amino-7-oxononanoate aminotransferase:Ribonucleotide reductase, alpha subunit:Exoribonuclease R:rRNA methylases:Cystathionine beta-lyases/cystathionine gamma-synthases:NAD-dependent aldehyde dehydrogenases:Flavodoxin reductases (ferredoxin-NADPH reductases) family 1:Predicted ATP-dependent protease:Arginine/ornithine N-succinyltransferase beta subunit:Predicted nucleic-acid-binding protein containing a Zn-ribbon domain:Signal transduction protein containing GAF and PtsI domains:Predicted metal-dependent hydrolase:Succinylarginine dihydrolase:Glucose dehydrogenase:Amino acid transport and metabolism:Nucleotide transport and metabolism:Carbohydrate transport and metabolism:Coenzyme transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:Posttranslational modification, protein turnover, chaperones:Glycolysis / Gluconeogenesis:Pentose phosphate pathway:Purine metabolism:Pyrimidine metabolism:Glycine serine and threonine metabolism:Cysteine and methionine metabolism:Valine leucine and isoleucine degradation:Arginine and proline metabolism:beta-Alanine metabolism:Selenocompound metabolism:Inositol phosphate metabolism:Propanoate metabolism:Nitrogen metabolism:Aminoacyl-tRNA biosynthesis:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:Phosphotransferase system (PTS):RNA degradation:General function prediction only:Signal transduction mechanisms:rRNA_methyl_3:3_prime_RNase:PTS_I_fam:MMSDH:TIGR02443:NrdJ_Z:PQQ_membr_DH:arg_catab_astD:arg_catab_astB:arg_catab_AOST:Information storage and processing:tRNA and rRNA base modification:Protein synthesis:Degradation of RNA:Transcription:Metabolism:Global:2'-Deoxyribonucleotide metabolism:Membrane Transport:Purines, pyrimidines, nucleosides, and nucleotides:Environmental Information Processing:Amino acids and amines:Folding Sorting and Degradation:Energy metabolism:Translation:Genetic Information Processing:Metabolism:Metabolism of Other Amino Acids:Amino Acid Metabolism:Nucleotide Metabolism:Energy Metabolism:Cellular processes and signaling:Carbohydrate Metabolism:Metabolism:Poorly characterized" 192 "Energy production and conversion:Glutathione synthase/Ribosomal protein S6 modification enzyme (glutaminyl transferase):1-acyl-sn-glycerol-3-phosphate acyltransferase:Cytosine deaminase and related metal-dependent hydrolases:Transcriptional regulator:Glycerophosphoryl diester phosphodiesterase:Enoyl-CoA hydratase/carnithine racemase:Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases):Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs:3-hydroxyacyl-CoA dehydrogenase:ABC-type transport system involved in multi-copper enzyme maturation, permease component:Predicted acyl-CoA transferases/carnitine dehydratase:Conserved protein/domain typically associated with flavoprotein oxygenases, DIM6/NTAB family:K+-transporting ATPase, c chain:AraC-type DNA-binding domain-containing proteins:Sugar phosphate permease:Uncharacterized protein, possibly involved in utilization of glycolate and propanediol:Large exoproteins involved in heme utilization or adhesion:Fe2+-dicitrate sensor, membrane component:Amino acid transport and metabolism:Nucleotide transport and metabolism:Carbohydrate transport and metabolism:Coenzyme transport and metabolism:Lipid transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:Inorganic ion transport and metabolism:Fatty acid metabolism:Valine leucine and isoleucine degradation:Geraniol degradation:Lysine degradation:Tyrosine metabolism:Benzoate degradation:Tryptophan metabolism:beta-Alanine metabolism:Glycerolipid metabolism:Glycerophospholipid metabolism:Aminobenzoate degradation:Propanoate metabolism:Butanoate metabolism:Atrazine degradation:Limonene and pinene degradation:Caprolactam degradation:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:Two-component system:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:Signal transduction mechanisms:kdpC:adhes_NPXG:HpaC:argP:Intracellular trafficking, secretion, and vesicular transport:Metabolism:Poorly characterized:Metabolism:Cellular processes and signaling:Information storage and processing:Cations and iron carrying compounds:Transport and binding proteins:DNA interactions:Regulatory functions:Metabolism:Global:Signal Transduction:Environmental Information Processing:Xenobiotics Biodegradation and Metabolism:Metabolism of Terpenoids and Polyketides:Metabolism of Other Amino Acids:Amino Acid Metabolism:Lipid Metabolism:Carbohydrate Metabolism" 193 "Gamma-glutamyltransferase:ABC-type branched-chain amino acid transport systems, ATPase component:ABC-type branched-chain amino acid transport systems, ATPase component:Branched-chain amino acid ABC-type transport system, permease components:ABC-type branched-chain amino acid transport systems, periplasmic component:Spermidine/putrescine-binding periplasmic protein:ABC-type amino acid transport system, permease component:ABC-type amino acid transport/signal transduction systems, periplasmic component/domain:ABC-type uncharacterized transport system, ATPase component:TRAP-type C4-dicarboxylate transport system, periplasmic component:Carbon starvation protein, predicted membrane protein:Arginine/lysine/ornithine decarboxylases:ABC-type uncharacterized transport system, periplasmic component:Phospholipase/lecithinase/hemolysin:ABC-type uncharacterized transport system, permease component:ABC-type arginine/histidine transport system, permease component:ABC-type branched-chain amino acid transport system, permease component:ABC-type arginine transport system, permease component:ABC-type histidine transport system, ATPase component:Amino acid transport and metabolism:Carbohydrate transport and metabolism:Lipid transport and metabolism:Arginine and proline metabolism:Taurine and hypotaurine metabolism:Selenocompound metabolism:Cyanoamino acid metabolism:Glutathione metabolism:Arachidonic acid metabolism:Metabolic pathways:ABC transporters:Two-component system:General function prediction only:Signal transduction mechanisms:g_glut_trans:dctP:HEQRo_perm_3TM:Biosynthesis of cofactors, prosthetic groups, and carriers:Carbohydrates, organic alcohols, and acids:Amino acids, peptides and amines:Transport and binding proteins:Cellular processes and signaling:Metabolism:Metabolism:Global:Poorly characterized:Signal Transduction:Metabolism:Membrane Transport:Environmental Information Processing:Metabolism of Other Amino Acids:Amino Acid Metabolism:Glutathione and analogs:Lipid Metabolism" 194 "Glucan phosphorylase:Glycosidases:Dienelactone hydrolase and related enzymes:Putative intracellular protease/amidase:Uncharacterized membrane protein:Cellulase M and related proteins:Neutral trehalase:Glucose/sorbosone dehydrogenases:Predicted outer membrane protein:Predicted membrane protein:Carbohydrate transport and metabolism:Starch and sucrose metabolism:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:Function unknown:PfpI:P_ylase:TIGR02284:treS_nterm:Carbohydrate Metabolism:Poorly characterized:Metabolism:Degradation of proteins, peptides, and glycopeptides:Protein fate:Biosynthesis and degradation of polysaccharides:Energy metabolism:Metabolism" 195 "Diaminopimelate decarboxylase:Cysteine synthase:Mg-dependent DNase:1-acyl-sn-glycerol-3-phosphate acyltransferase:Predicted dehydrogenase:Membrane protein TerC, possibly involved in tellurium resistance:DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog:Predicted signal transduction protein:Serine phosphatase RsbU, regulator of sigma subunit:SAM-dependent methyltransferases related to tRNA (uracil-5-)-methyltransferase:Tfp pilus assembly protein PilZ:Heme oxygenase:Uncharacterized protein conserved in bacteria:Putative Zn-dependent protease:Amino acid transport and metabolism:Lipid transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:Replication, recombination and repair:Cell motility:Inorganic ion transport and metabolism:Cysteine and methionine metabolism:Arginine and proline metabolism:Selenocompound metabolism:Glutathione metabolism:Pyruvate metabolism:Sulfur metabolism:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:RNA polymerase:General function prediction only:Function unknown:Signal transduction mechanisms:TIGR00010:rumA:cysKM:mal_quin_oxido:sigma70-ECF:R_switched_YjbE:Intracellular trafficking, secretion, and vesicular transport:Metabolism:Cellular processes and signaling:Information storage and processing:Serine family:Amino acid biosynthesis:Enzymes of unknown specificity:Unknown function:tRNA and rRNA base modification:Protein synthesis:TCA cycle:Energy metabolism:Metabolism:Metabolism:Global:Transcription:Genetic Information Processing:Metabolism of Other Amino Acids:Amino Acid Metabolism:Energy Metabolism:Poorly characterized:Carbohydrate Metabolism" 196 "Predicted epimerase, PhzC/PhzF homolog:Sugar kinases, ribokinase family:ABC-type antimicrobial peptide transport system, permease component:Transcriptional regulator:Glycine/D-amino acid oxidases (deaminating):Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain:ABC-type amino acid transport/signal transduction systems, periplasmic component/domain:Cation/multidrug efflux pump:Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases):Outer membrane protein:Multidrug resistance efflux pump:3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases:ABC-type proline/glycine betaine transport systems, periplasmic components:Uncharacterized protein conserved in bacteria:Lysophospholipase L1 and related esterases:Arabinose efflux permease:Protocatechuate 3,4-dioxygenase beta subunit:Signal transduction histidine kinase involved in nitrogen fixation and metabolism regulation:Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain:Amino acid transport and metabolism:Carbohydrate transport and metabolism:Lipid transport and metabolism:Transcription:Cell wall/membrane/envelope biogenesis:Fructose and mannose metabolism:Fatty acid biosynthesis:Valine leucine and isoleucine degradation:Benzoate degradation:Starch and sucrose metabolism:Amino sugar and nucleotide sugar metabolism:Polycyclic aromatic hydrocarbon degradation:Aminobenzoate degradation:Biosynthesis of unsaturated fatty acids:Metabolic pathways:Microbial metabolism in diverse environments:ABC transporters:Two-component system:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:Function unknown:Signal transduction mechanisms:sensory_box:PhzF_family:cztR_silR_copR:RND_mfp:outer_NodT:protocat_alph:Intracellular trafficking, secretion, and vesicular transport:Defense mechanisms:Energy metabolism:Metabolism:Global:Metabolism:Signal Transduction:Membrane Transport:Environmental Information Processing:Xenobiotics Biodegradation and Metabolism:Amino Acid Metabolism:Lipid Metabolism:Toxin production and resistance:Carbohydrate Metabolism:Information storage and processing:Cellular processes and signaling:Metabolism:Poorly characterized:Cellular processes:Porins:Unknown substrate:Transport and binding proteins:Small molecule interactions:Regulatory functions:Other" 197 "Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases:Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily):Spermidine/putrescine-binding periplasmic protein:Membrane-fusion protein:Gamma-aminobutyrate permease and related permeases:Pyruvate-formate lyase-activating enzyme:Putative multicopper oxidases:2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase:Protein tyrosine/serine phosphatase:Protein related to penicillin acylase:Uncharacterized protein conserved in bacteria:Carbohydrate-selective porin:Uncharacterized protein involved in copper resistance:Amino acid transport and metabolism:Coenzyme transport and metabolism:Translation, ribosomal structure and biogenesis:Cell wall/membrane/envelope biogenesis:Posttranslational modification, protein turnover, chaperones:Inorganic ion transport and metabolism:Penicillin and cephalosporin biosynthesis:Arginine and proline metabolism:Phenylalanine metabolism:Tryptophan metabolism:Cyanoamino acid metabolism:Aminobenzoate degradation:Styrene degradation:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:Bacterial secretion system:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:Function unknown:Signal transduction mechanisms:TAT_signal_seq:vgr_GE:NrdG2:Metabolism:Cellular processes and signaling:Information storage and processing:Protein modification and repair:Protein and peptide secretion and trafficking:Protein fate:Metabolism:Metabolism:Global:Membrane Transport:Environmental Information Processing:Xenobiotics Biodegradation and Metabolism:Biosynthesis of Other Secondary Metabolites:Metabolism of Other Amino Acids:Poorly characterized:Amino Acid Metabolism" 198 "Energy production and conversion:Glutamine phosphoribosylpyrophosphate amidotransferase:Glutamine amidotransferase:Methionyl-tRNA synthetase:Argininosuccinate lyase:Glycerol-3-phosphate dehydrogenase:Diaminopimelate epimerase:CTP synthase (UTP-ammonia lyase):Glutathione S-transferase:Rieske Fe-S protein:dTDP-D-glucose 4,6-dehydratase:RecG-like helicase:Cytochrome b subunit of the bc complex:Phosphohistidine phosphatase SixA:2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase:Uncharacterized protein involved in purine metabolism:ABC-type uncharacterized transport system, periplasmic component:Signal transduction histidine kinase regulating citrate/malate metabolism:Amino acid transport and metabolism:Nucleotide transport and metabolism:Coenzyme transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:Replication, recombination and repair:Cell wall/membrane/envelope biogenesis:Posttranslational modification, protein turnover, chaperones:Ubiquinone and other terpenoid-quinone biosynthesis:Oxidative phosphorylation:Purine metabolism:Pyrimidine metabolism:Alanine aspartate and glutamate metabolism:Lysine biosynthesis:Arginine and proline metabolism:Histidine metabolism:Selenocompound metabolism:Streptomycin biosynthesis:Polyketide sugar unit biosynthesis:Glycerophospholipid metabolism:Aminoacyl-tRNA biosynthesis:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:Homologous recombination:General function prediction only:Signal transduction mechanisms:sixA:PyrG:metG:recG:DapF:argH:purF:dTDP_gluc_dehyt:Rieske_proteo:IMP_synth_hisH:UbiG:Biosynthesis of cofactors, prosthetic groups, and carriers:Energy Metabolism:Lipid Metabolism:Nucleotide Metabolism:Amino Acid Metabolism:Metabolism of Other Amino Acids:Metabolism of Cofactors and Vitamins:Metabolism of Terpenoids and Polyketides:Biosynthesis of Other Secondary Metabolites:Genetic Information Processing:Translation:Replication and Repair:Global:Metabolism:Energy metabolism:Electron transport:Purines, pyrimidines, nucleosides, and nucleotides:Purine ribonucleotide biosynthesis:Pyrimidine ribonucleotide biosynthesis:Regulatory functions:Protein interactions:DNA metabolism:DNA replication, recombination, and repair:Protein synthesis:tRNA aminoacylation:Amino acid biosynthesis:Aspartate family:Glutamate family:Histidine family:Metabolism:Menaquinone and ubiquinone:Cell envelope:Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides:Information storage and processing:Cellular processes and signaling:Metabolism:Poorly characterized" 199 "Energy production and conversion:Mannitol-1-phosphate/altronate dehydrogenases:Membrane protease subunits, stomatin/prohibitin homologs:ABC-type sugar transport system, permease component:Zn-dependent protease with chaperone function:Glutathione S-transferase:Sugar (pentulose and hexulose) kinases:ABC-type sugar transport systems, permease components:Amidases related to nicotinamidase:Pirin-related protein:Probable taurine catabolism dioxygenase:AraC-type DNA-binding domain-containing proteins:Aromatic ring hydroxylase:Cytochrome c553:Na+-transporting NADH:ubiquinone oxidoreductase, subunit NqrF:Arylsulfatase A and related enzymes:Pyoverdine/dityrosine biosynthesis protein:Protein involved in meta-pathway of phenol degradation:Phenylpropionate dioxygenase and related ring-hydroxylating dioxygenases, large terminal subunit:Small subunit of phenylpropionate dioxygenase:Carbohydrate transport and metabolism:Transcription:Posttranslational modification, protein turnover, chaperones:Inorganic ion transport and metabolism:Pentose and glucuronate interconversions:Fructose and mannose metabolism:Aminobenzoate degradation:Nitrogen metabolism:Metabolic pathways:Microbial metabolism in diverse environments:ABC transporters:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:maiA:XylB:anthran_1_2_A:anthran_1_2_B:Information storage and processing:Sugars:Amino acids and amines:Energy metabolism:Metabolism:Global:Membrane Transport:Environmental Information Processing:Xenobiotics Biodegradation and Metabolism:Energy Metabolism:Metabolism:Carbohydrate Metabolism:Poorly characterized:Metabolism:Cellular processes and signaling" 200 "Acetyltransferases:ATPases with chaperone activity, ATP-binding subunit:Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases:Multidrug resistance efflux pump:ABC-type phosphate/phosphonate transport system, periplasmic component:Uncharacterized protein conserved in bacteria:Uncharacterized protein conserved in bacteria:Uncharacterized protein conserved in bacteria:Uncharacterized protein conserved in bacteria:Predicted periplasmic ligand-binding sensor domain:Flp pilus assembly protein CpaB:Flp pilus assembly protein TadB:Amino acid transport and metabolism:Posttranslational modification, protein turnover, chaperones:Inorganic ion transport and metabolism:Bacterial secretion system:General function prediction only:Function unknown:Signal transduction mechanisms:sensory_box:pilus_cpaB:VI_ClpV1:IV_VI_DotU:VI_chp_6:VI_chp_8:Intracellular trafficking, secretion, and vesicular transport:Defense mechanisms:Poorly characterized:Metabolism:Cellular processes and signaling:Pathogenesis:Cellular processes:Small molecule interactions:Regulatory functions:Environmental Information Processing:Membrane Transport" 201 "Energy production and conversion:Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases:Transcriptional regulator:Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily):Sulfate permease and related transporters (MFS superfamily):Glycine/D-amino acid oxidases (deaminating):NAD-dependent aldehyde dehydrogenases:Outer membrane protein:Mn2+ and Fe2+ transporters of the NRAMP family:FOG: EAL domain:Sugar phosphate permease:Predicted hydrolase of the alpha/beta superfamily:Arylsulfatase A and related enzymes:Predicted membrane protein:Urea transporter:Signal transduction histidine kinase:Amino acid transport and metabolism:Carbohydrate transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:Cell wall/membrane/envelope biogenesis:Inorganic ion transport and metabolism:Arginine and proline metabolism:Phenylalanine metabolism:Tryptophan metabolism:Cyanoamino acid metabolism:Aminobenzoate degradation:Styrene degradation:Caprolactam degradation:Metabolic pathways:Microbial metabolism in diverse environments:Two-component system:General function prediction only:Function unknown:Signal transduction mechanisms:sensory_box:2A0115:nramp:outer_NodT:Intracellular trafficking, secretion, and vesicular transport:Cellular processes and signaling:Amino Acid Metabolism:Metabolism of Other Amino Acids:Xenobiotics Biodegradation and Metabolism:Environmental Information Processing:Signal Transduction:Global:Metabolism:Regulatory functions:Small molecule interactions:Transport and binding proteins:Carbohydrates, organic alcohols, and acids:Cations and iron carrying compounds:Porins:Information storage and processing:Metabolism:Metabolism:Poorly characterized" 202 "RNA processing and modification:3-polyprenyl-4-hydroxybenzoate decarboxylase:Selenocysteine lyase:dsRNA-specific ribonuclease:Rhodanese-related sulfurtransferase:Signal transduction histidine kinase:Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain:UDP-N-acetylmuramate-alanine ligase:ABC-type amino acid transport/signal transduction systems, periplasmic component/domain:Pyridoxal phosphate biosynthesis protein:Aspartate ammonia-lyase:Chromosome segregation ATPases:Oligoribonuclease (3'->5' exoribonuclease):SufE protein probably involved in Fe-S center assembly:Uncharacterized conserved protein:Uncharacterized protein affecting Mg2+/Co2+ transport:Type IV secretory pathway, VirJ component:Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain:Cell cycle control, cell division, chromosome partitioning:Amino acid transport and metabolism:Coenzyme transport and metabolism:Transcription:Cell wall/membrane/envelope biogenesis:Inorganic ion transport and metabolism:Ubiquinone and other terpenoid-quinone biosynthesis:Alanine aspartate and glutamate metabolism:Vitamin B6 metabolism:Nitrogen metabolism:Metabolic pathways:Biosynthesis of secondary metabolites:Two-component system:General function prediction only:Function unknown:Signal transduction mechanisms:sensory_box:ubiX_pad:pdxJ:aspA:mpl:SMC_prok_B:RNaseIII:Intracellular trafficking, secretion, and vesicular transport:Cell envelope:Energy Metabolism:Amino Acid Metabolism:Metabolism of Cofactors and Vitamins:Environmental Information Processing:Signal Transduction:Global:Metabolism:Energy metabolism:Amino acids and amines:Regulatory functions:Small molecule interactions:DNA metabolism:Chromosome-associated proteins:Transcription:RNA processing:Unknown function:Enzymes of unknown specificity:Biosynthesis of cofactors, prosthetic groups, and carriers:Pyridoxine:Metabolism:Biosynthesis and degradation of murein sacculus and peptidoglycan:Information storage and processing:Cellular processes and signaling:Metabolism:Poorly characterized" 203 "Cysteine synthase:Zn-dependent hydrolases, including glyoxylases:Transcriptional regulator:Glutathione S-transferase:Catalase:Sortase and related acyltransferases:Putative threonine efflux protein:Uncharacterized conserved protein:Fatty-acid desaturase:Uncharacterized membrane protein:FOG: GGDEF domain:Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains:O-acetylhomoserine sulfhydrylase:Uncharacterized conserved protein:Signal transduction histidine kinase, nitrogen specific:Amino acid transport and metabolism:Lipid transport and metabolism:Transcription:Cell wall/membrane/envelope biogenesis:Posttranslational modification, protein turnover, chaperones:Inorganic ion transport and metabolism:Cysteine and methionine metabolism:Tryptophan metabolism:Selenocompound metabolism:Methane metabolism:Sulfur metabolism:Metabolic pathways:Microbial metabolism in diverse environments:Two-component system:General function prediction only:Function unknown:Signal transduction mechanisms:GGDEF:OAH_OAS_sulfhy:ntrC:DNA:Information storage and processing:Energy Metabolism:Amino Acid Metabolism:Metabolism of Other Amino Acids:Environmental Information Processing:Signal Transduction:Global:Metabolism:Hypothetical proteins:Conserved:Amino acid biosynthesis:Serine family:Signal transduction:Two-component systems:Other:Metabolism:Cellular processes and signaling:Metabolism:Poorly characterized" 204 "Phosphoribosylformylglycinamidine (FGAM) synthase, synthetase domain:Phosphoribosylformimino-5-aminoimidazole carboxamide ribonucleotide (ProFAR) isomerase:Imidazoleglycerol-phosphate synthase:Glycosyltransferase:GMP synthase, PP-ATPase domain/subunit:Signal peptidase I:Cell division protein FtsI/penicillin-binding protein 2:ADP-heptose:LPS heptosyltransferase:FOG: GGDEF domain:Serine phosphatase RsbU, regulator of sigma subunit:Methylase of polypeptide chain release factors:Amino acid transport and metabolism:Nucleotide transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:Cell wall/membrane/envelope biogenesis:Purine metabolism:Histidine metabolism:Lipopolysaccharide biosynthesis:Peptidoglycan biosynthesis:Metabolic pathways:Biosynthesis of secondary metabolites:Protein export:Signal transduction mechanisms:TIGR00007:GGDEF:hemK_fam:hisF:guaA_Cterm:FGAM_synt:heptsyl_trn_I:heptsyl_trn_II:sigpep_I_bact:pbp2_mrdA:Intracellular trafficking, secretion, and vesicular transport:Biosynthesis and degradation of murein sacculus and peptidoglycan:Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides:Information storage and processing:Cellular processes and signaling:Metabolism:Histidine family:Amino acid biosynthesis:Protein modification and repair:Protein and peptide secretion and trafficking:Protein fate:Purine ribonucleotide biosynthesis:Purines, pyrimidines, nucleosides, and nucleotides:Metabolism:Metabolism:Global:Folding Sorting and Degradation:Genetic Information Processing:Glycan Biosynthesis and Metabolism:Amino Acid Metabolism:Signal transduction:Nucleotide Metabolism:Other:Cell envelope" 205 "Energy production and conversion:Conserved domain frequently associated with peptide methionine sulfoxide reductase:Glutathione peroxidase:Cytosine deaminase and related metal-dependent hydrolases:Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases:Uncharacterized homolog of gamma-carboxymuconolactone decarboxylase subunit:Signal transduction histidine kinase:Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain:Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes:Transcriptional regulators:Transcriptional regulators:Predicted metalloprotease:DNA-binding HTH domain-containing proteins:Uncharacterized protein conserved in bacteria:Predicted membrane protein:Uncharacterized protein conserved in bacteria:Nucleotide transport and metabolism:Carbohydrate transport and metabolism:Transcription:Posttranslational modification, protein turnover, chaperones:Glutathione metabolism:Arachidonic acid metabolism:General function prediction only:Function unknown:Signal transduction mechanisms:TIGR00357:ahpD_dom:his_ut_repres:hutF:Information storage and processing:General:Unknown function:Adaptations to atypical conditions:Cellular processes:DNA interactions:Regulatory functions:Amino acids and amines:Energy metabolism:Metabolism of Other Amino Acids:Metabolism:Lipid Metabolism:Poorly characterized:Metabolism:Cellular processes and signaling" 206 "Energy production and conversion:Mg-dependent DNase:Acetyl-CoA acetyltransferase:Glutathione synthase/Ribosomal protein S6 modification enzyme (glutaminyl transferase):FAD/FMN-containing dehydrogenases:Ketopantoate hydroxymethyltransferase:NADPH:quinone reductase and related Zn-dependent oxidoreductases:Urease accessory protein UreH:Hydrolases of the alpha/beta superfamily:Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs:ABC-type Fe3+ transport system, permease component:Acyl carrier protein phosphodiesterase:Predicted membrane-associated, metal-dependent hydrolase:AraC-type DNA-binding domain-containing proteins:Predicted membrane protein:Uncharacterized protein involved in formate dehydrogenase formation:Phospholipase/lecithinase/hemolysin:Signal transduction histidine kinase:Uncharacterized protein conserved in bacteria:Amino acid transport and metabolism:Coenzyme transport and metabolism:Lipid transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:Replication, recombination and repair:Posttranslational modification, protein turnover, chaperones:Inorganic ion transport and metabolism:Fatty acid metabolism:Valine leucine and isoleucine degradation:Geraniol degradation:Benzoate degradation:alpha-Linolenic acid metabolism:Pantothenate and CoA biosynthesis:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:ABC transporters:General function prediction only:Function unknown:Signal transduction mechanisms:panB:mdcA:TAT_signal_seq:FdhE:YD_repeat_2x:AcCoA-C-Actrans:Information storage and processing:Lipid Metabolism:Amino Acid Metabolism:Metabolism of Cofactors and Vitamins:Metabolism of Terpenoids and Polyketides:Xenobiotics Biodegradation and Metabolism:Environmental Information Processing:Membrane Transport:Global:Metabolism:Energy metabolism:Other:Fatty acid and phospholipid metabolism:Other:Protein fate:Protein and peptide secretion and trafficking:Biosynthesis of cofactors, prosthetic groups, and carriers:Pantothenate and coenzyme A:Metabolism:Cellular processes and signaling:Metabolism:Poorly characterized" 207 "Energy production and conversion:Trk-type K+ transport systems, membrane components:Fatty acid/phospholipid biosynthesis enzyme:Phosphopantothenoylcysteine synthetase/decarboxylase:CDP-diglyceride synthetase:Uncharacterized conserved protein:Coproporphyrinogen III oxidase and related Fe-S oxidoreductases:Amino acid permeases:Amino acid transporters:ABC-type amino acid transport/signal transduction systems, periplasmic component/domain:Fe-S oxidoreductase:Gamma-aminobutyrate permease and related permeases:Metal-dependent hydrolases of the beta-lactamase superfamily I:Homoserine acetyltransferase:Lysophospholipase:Uncharacterized protein conserved in bacteria:Amino acid transport and metabolism:Coenzyme transport and metabolism:Lipid transport and metabolism:Inorganic ion transport and metabolism:Cysteine and methionine metabolism:Glycerolipid metabolism:Glycerophospholipid metabolism:Pantothenate and CoA biosynthesis:Porphyrin and chlorophyll metabolism:Sulfur metabolism:Metabolic pathways:Biosynthesis of secondary metabolites:General function prediction only:Function unknown:Signal transduction mechanisms:plsX:coaBC_dfp:hemN_rel:araaP:homoserO_Ac_trn:metW:SAM_YgiQ:Amino acids, peptides and amines:Transport and binding proteins:Biosynthesis:Fatty acid and phospholipid metabolism:Metabolism:Metabolism:Global:Metabolism of Cofactors and Vitamins:Amino Acid Metabolism:Lipid Metabolism:Amino acid biosynthesis:Energy Metabolism:Aspartate family:Biosynthesis of cofactors, prosthetic groups, and carriers:Heme, porphyrin, and cobalamin:Pantothenate and coenzyme A:Cellular processes and signaling:Metabolism:Poorly characterized:Enzymes of unknown specificity:Unknown function" 208 "N-formylmethionyl-tRNA deformylase:Ribonuclease HI:Zn-dependent hydrolases, including glyoxylases:Glutathione S-transferase:Predicted transcriptional regulators:Predicted thioesterase:Uncharacterized protein SCO1/SenC/PrrC, involved in biogenesis of respiratory and photosynthetic systems:ABC-type proline/glycine betaine transport systems, periplasmic components:Glucose/sorbosone dehydrogenases:Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain:Predicted acetyltransferase:Uncharacterized conserved protein:Uncharacterized protein conserved in bacteria:Predicted metal-binding protein:Uncharacterized protein conserved in bacteria:Amino acid transport and metabolism:Carbohydrate transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:Replication, recombination and repair:Posttranslational modification, protein turnover, chaperones:ABC transporters:DNA replication:General function prediction only:Function unknown:Signal transduction mechanisms:TIGR00051:ABC_choline_bnd:Amino acids, peptides and amines:Transport and binding proteins:Membrane Transport:Environmental Information Processing:Genetic Information Processing:Replication and Repair:Poorly characterized:Metabolism:Cellular processes and signaling:Information storage and processing:General:Unknown function" 209 "Energy production and conversion:Glutathione peroxidase:Universal stress protein UspA and related nucleotide-binding proteins:Predicted thioesterase:Acylphosphatases:Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor):DnaK suppressor protein:Predicted membrane protein:Uncharacterized protein, similar to the N-terminal domain of Lon protease:Regulator of competence-specific genes:Plasmid maintenance system antidote protein:Activator of osmoprotectant transporter ProP:Ketosteroid isomerase-related protein:Uncharacterized conserved small protein:Transcription:Posttranslational modification, protein turnover, chaperones:Glutathione metabolism:Arachidonic acid metabolism:Pyruvate metabolism:Aminobenzoate degradation:Microbial metabolism in diverse environments:General function prediction only:Function unknown:Signal transduction mechanisms:C4_traR_proteo:antidote_HigA:Poorly characterized:Carbohydrate Metabolism:Lipid Metabolism:Metabolism of Other Amino Acids:Xenobiotics Biodegradation and Metabolism:Global:Metabolism:Mobile and extrachromosomal element functions:Prophage functions:Other:Information storage and processing:Cellular processes and signaling:Metabolism:Metabolism" 210 "Ribosomal protein S10:Ribosomal protein L27:Acyl carrier protein:Ribosomal protein L21:Ribosomal protein L33:Translation initiation factor 3 (IF-3):Ribosomal protein L35:Ribosomal protein L20:Ribosomal protein L32:Cold shock proteins:Lipid transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:Ribosome:Secondary metabolites biosynthesis, transport and catabolism:rpmI_bact:S21p:L21:L27:infC:acyl_carrier:rpmG_bact:rpmF_bact:rplT_bact:rpsJ_bact:thioredoxin:Protein synthesis:Translation:Energy metabolism:Electron transport:Fatty acid and phospholipid metabolism:Biosynthesis:Genetic Information Processing:Ribosomal proteins: synthesis and modification:Translation factors:Information storage and processing:Metabolism" 211 "Energy production and conversion:Acetyl-CoA acetyltransferase:Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases:Glycosyltransferase:DNA polymerase III, alpha subunit:Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily):ABC-type amino acid transport/signal transduction systems, periplasmic component/domain:Predicted UDP-glucose 6-dehydrogenase:Probable taurine catabolism dioxygenase:Arabinose efflux permease:Uncharacterized protein conserved in bacteria:Phosphodiesterase/alkaline phosphatase D:Proline racemase:Predicted membrane protein:Protein involved in meta-pathway of phenol degradation:Amino acid transport and metabolism:Carbohydrate transport and metabolism:Lipid transport and metabolism:Replication, recombination and repair:Cell wall/membrane/envelope biogenesis:Inorganic ion transport and metabolism:Pentose and glucuronate interconversions:Ascorbate and aldarate metabolism:Fatty acid metabolism:Valine leucine and isoleucine degradation:Geraniol degradation:Benzoate degradation:Starch and sucrose metabolism:Amino sugar and nucleotide sugar metabolism:alpha-Linolenic acid metabolism:Aminobenzoate degradation:Folate biosynthesis:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:ABC transporters:Two-component system:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:Function unknown:Signal transduction mechanisms:polc:AcCoA-C-Actrans:NDP-sugDHase:Poorly characterized:Metabolism:Global:Metabolism:Cellular processes and signaling:Information storage and processing:DNA replication, recombination, and repair:Signal Transduction:DNA metabolism:Membrane Transport:Environmental Information Processing:Other:Xenobiotics Biodegradation and Metabolism:Metabolism of Terpenoids and Polyketides:Fatty acid and phospholipid metabolism:Metabolism of Cofactors and Vitamins:Amino Acid Metabolism:Metabolism:Lipid Metabolism:Carbohydrate Metabolism" 212 "Energy production and conversion:Molybdopterin converting factor, large subunit:Molybdenum cofactor biosynthesis enzyme:Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily):Glycine/D-amino acid oxidases (deaminating):Methyl-accepting chemotaxis protein:ADP-ribose pyrophosphatase:Na+/H+-dicarboxylate symporters:Transcriptional regulator:Predicted transcriptional regulators:Uncharacterized conserved protein:Pirin-related protein:Predicted redox protein, regulator of disulfide bond formation:Rubredoxin:Transcriptional regulators:Transcriptional regulators:Molybdopterin converting factor, small subunit:Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain:Stringent starvation protein B:Uncharacterized conserved protein:Aspartyl/asparaginyl beta-hydroxylase and related dioxygenases:Conserved secreted protein:Amino acid transport and metabolism:Nucleotide transport and metabolism:Coenzyme transport and metabolism:Transcription:Cell motility:Posttranslational modification, protein turnover, chaperones:Two-component system:Bacterial chemotaxis:Sulfur relay system:General function prediction only:Function unknown:Signal transduction mechanisms:moaC:moaD:Environmental Information Processing:Folding Sorting and Degradation:Genetic Information Processing:Poorly characterized:Metabolism:Cellular processes and signaling:Information storage and processing:Molybdopterin:Biosynthesis of cofactors, prosthetic groups, and carriers:Cell Motility:Cellular Processes:Signal Transduction" 213 "Energy production and conversion:Succinyl-CoA synthetase, beta subunit:Succinyl-CoA synthetase, alpha subunit:Ribonucleotide reductase, beta subunit:Ribonucleotide reductase, alpha subunit:Succinate dehydrogenase/fumarate reductase, Fe-S protein subunit:Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component, and related enzymes:2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, and related enzymes:Succinate dehydrogenase/fumarate reductase, flavoprotein subunit:Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes:Pyruvate dehydrogenase complex, dehydrogenase (E1) component:Nucleotide transport and metabolism:Glycolysis / Gluconeogenesis:Citrate cycle (TCA cycle):Oxidative phosphorylation:Purine metabolism:Pyrimidine metabolism:Glycine serine and threonine metabolism:Valine leucine and isoleucine degradation:Valine leucine and isoleucine biosynthesis:Lysine degradation:Tryptophan metabolism:Pyruvate metabolism:Toluene degradation:Propanoate metabolism:Butanoate metabolism:C5-Branched dibasic acid metabolism:Carbon fixation pathways in prokaryotes:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:2oxo_dh_E1:dhsB:aceE:sucCoAbeta:sucCoAalpha:sucB:PDHac_trf_long:lipoamide_DH:sdhA_frdA_Gneg:NrdE_NrdA:Carbohydrate Metabolism:Energy metabolism:Pyruvate dehydrogenase:TCA cycle:Purines, pyrimidines, nucleosides, and nucleotides:2'-Deoxyribonucleotide metabolism:Metabolism:Metabolism:Global:Xenobiotics Biodegradation and Metabolism:Amino Acid Metabolism:Nucleotide Metabolism:Energy Metabolism:Metabolism" 214 "Chorismate synthase:Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), A subunit:Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases:Predicted S-adenosylmethionine-dependent methyltransferase involved in bacterial cell division:Prolyl-tRNA synthetase:NAD/FAD-utilizing enzyme apparently involved in cell division:Adenine/guanine phosphoribosyltransferases and related PRPP-binding proteins:Acetylglutamate kinase:tRNA nucleotidyltransferase/poly(A) polymerase:Multimeric flavodoxin WrbA:Predicted sugar phosphate isomerase involved in capsule formation:Phosphomannomutase:Transcription termination factor:ATPases involved in chromosome partitioning:Arsenate reductase and related proteins, glutaredoxin family:Uncharacterized conserved protein, contains double-stranded beta-helix domain:Uncharacterized protein conserved in bacteria:Predicted membrane protein:Cell cycle control, cell division, chromosome partitioning:Amino acid transport and metabolism:Nucleotide transport and metabolism:Carbohydrate transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:Replication, recombination and repair:Cell wall/membrane/envelope biogenesis:Inorganic ion transport and metabolism:Glycolysis / Gluconeogenesis:Pentose phosphate pathway:Fructose and mannose metabolism:Galactose metabolism:Purine metabolism:Cysteine and methionine metabolism:Lysine biosynthesis:Arginine and proline metabolism:Phenylalanine tyrosine and tryptophan biosynthesis:Starch and sucrose metabolism:Amino sugar and nucleotide sugar metabolism:Streptomycin biosynthesis:Aminoacyl-tRNA biosynthesis:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:RNA degradation:General function prediction only:Function unknown:arsC:aroC:gidA:gidB:kpsF:proS_fam_II:argB:rho:gyrA:apt:flav_wrbA:pcnB:salvage_mtnB:Aspartate family:Carbohydrate Metabolism:Nucleotide Metabolism:Amino Acid Metabolism:Biosynthesis of Other Secondary Metabolites:Genetic Information Processing:Translation:Folding Sorting and Degradation:Global:Metabolism:Energy metabolism:Electron transport:Sugars:Purines, pyrimidines, nucleosides, and nucleotides:Salvage of nucleosides and nucleotides:DNA metabolism:DNA replication, recombination, and repair:Transcription:Transcription factors:Protein synthesis:tRNA aminoacylation:tRNA and rRNA base modification:Cellular processes:Detoxification:Amino acid biosynthesis:Aromatic amino acid family:Metabolism:Glutamate family:Information storage and processing:Cellular processes and signaling:Metabolism:Poorly characterized" 215 "Adenylosuccinate lyase:Glycosyltransferase:ATPase components of ABC transporters with duplicated ATPase domains:SAM-dependent methyltransferases:Uncharacterized homolog of gamma-carboxymuconolactone decarboxylase subunit:Spermidine/putrescine-binding periplasmic protein:Mannose-1-phosphate guanylyltransferase:GDP-D-mannose dehydratase:ABC-type spermidine/putrescine transport system, permease component I:ABC-type spermidine/putrescine transport system, permease component II:ABC-type polysaccharide/polyol phosphate export systems, permease component:Predicted acyltransferases:Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains:ABC-type spermidine/putrescine transport systems, ATPase components:Signal transduction histidine kinase regulating C4-dicarboxylate transport system:Amino acid transport and metabolism:Nucleotide transport and metabolism:Carbohydrate transport and metabolism:Lipid transport and metabolism:Cell wall/membrane/envelope biogenesis:Fructose and mannose metabolism:Benzoate degradation:Amino sugar and nucleotide sugar metabolism:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:ABC transporters:Two-component system:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:Function unknown:Signal transduction mechanisms:potA:gmd:GMP_PMI:decarb_PcaC:protocat_pcaB:Cellular processes and signaling:Carbohydrate Metabolism:Xenobiotics Biodegradation and Metabolism:Environmental Information Processing:Membrane Transport:Signal Transduction:Global:Metabolism:Energy metabolism:Other:Transport and binding proteins:Amino acids, peptides and amines:Cell envelope:Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides:Metabolism:Metabolism:Poorly characterized" 216 "NAD synthase:Cell division GTPase:Predicted S-adenosylmethionine-dependent methyltransferase involved in cell envelope biogenesis:UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N-acetylglucosamine-1-phosphate transferase:UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase:Cell division protein FtsI/penicillin-binding protein 2:UDP-N-acetylmuramyl tripeptide synthase:UDP-N-acetylmuramyl pentapeptide synthase:UDP-N-acetylmuramoylalanine-D-glutamate ligase:Bacterial cell division membrane protein:UDP-N-acetylmuramate-alanine ligase:Actin-like ATPase involved in cell division:ADP-ribose pyrophosphatase:Nicotinic acid mononucleotide adenylyltransferase:D-alanine-D-alanine ligase and related ATP-grasp enzymes:Amidases related to nicotinamidase:Nicotinic acid phosphoribosyltransferase:Cell division septal protein:Uncharacterized protein conserved in bacteria:Cell division protein:Cell cycle control, cell division, chromosome partitioning:Nucleotide transport and metabolism:Coenzyme transport and metabolism:Cell wall/membrane/envelope biogenesis:Lysine biosynthesis:D-Glutamine and D-glutamate metabolism:D-Alanine metabolism:Peptidoglycan biosynthesis:Nicotinate and nicotinamide metabolism:Nitrogen metabolism:Metabolic pathways:Secondary metabolites biosynthesis, transport and catabolism:Function unknown:TIGR00006:ftsZ:cyt_tran_rel:TIGR00242:mraY:nadE:murC:murE:murD:murG:murF:ftsA:D_ala_D_alaTIGR:NAPRTase:ftsL_broad:ftsW:Cell envelope:Pyridine nucleotides:Biosynthesis of cofactors, prosthetic groups, and carriers:General:Unknown function:Cell division:Cellular processes:Metabolism:Metabolism:Global:Metabolism of Cofactors and Vitamins:Glycan Biosynthesis and Metabolism:Metabolism of Other Amino Acids:Amino Acid Metabolism:Poorly characterized:Energy Metabolism:Metabolism:Cellular processes and signaling:Biosynthesis and degradation of murein sacculus and peptidoglycan" 217 "Ribosomal protein L13:Ribosomal protein S9:Ribosomal protein S15P/S13E:Ribosomal protein L28:Ribosomal protein S18:Ribosomal protein S20:Ribosomal protein L20:Ribosomal protein L32:Ribosomal protein L9:Ribosomal protein S6:Predicted metal-binding, possibly nucleic acid-binding protein:Translation, ribosomal structure and biogenesis:Ribosome:General function prediction only:L28:S20:L9:S18:S6:S15_bact:rpmF_bact:rplT_bact:rplM_bact:Information storage and processing:Translation:Protein synthesis:Ribosomal proteins: synthesis and modification:Genetic Information Processing:Poorly characterized" 218 "ABC-type amino acid transport/signal transduction systems, periplasmic component/domain:Predicted phosphohydrolases:TRAP-type C4-dicarboxylate transport system, periplasmic component:Predicted SAM-dependent methyltransferase:Type III secretory pathway, component EscR:Type III secretory pathway, component EscT:Type III secretory pathway, component EscU:NAD+--asparagine ADP-ribosyltransferase:Amino acid transport and metabolism:Carbohydrate transport and metabolism:Bacterial secretion system:General function prediction only:Signal transduction mechanisms:dctP:yscR:fliR_like_III:FlhB_rel_III:type_III_yscP:YscW:LcrR:Intracellular trafficking, secretion, and vesicular transport:Metabolism:Membrane Transport:Transport and binding proteins:Carbohydrates, organic alcohols, and acids:Cellular processes:Pathogenesis:Cellular processes and signaling:Environmental Information Processing:Poorly characterized" 219 "Imidazoleglycerol-phosphate synthase:Glutamine amidotransferase:UDP-N-acetylglucosamine 2-epimerase:Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis:Glycosyltransferase:Nucleoside-diphosphate-sugar epimerases:UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N-acetylglucosamine-1-phosphate transferase:Predicted dehydrogenases and related proteins:UDP-N-acetyl-D-mannosaminuronate dehydrogenase:Acyl-[acyl carrier protein]--UDP-N-acetylglucosamine O-acyltransferase:Amino acid transport and metabolism:Carbohydrate transport and metabolism:Cell wall/membrane/envelope biogenesis:Histidine metabolism:Metabolic pathways:Biosynthesis of secondary metabolites:General function prediction only:wecB:IMP_synth_hisH:NDP-sugDHase:WbuZ:Metabolism:Amino Acid Metabolism:Global:Metabolism:Amino acid biosynthesis:Histidine family:Cell envelope:Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides:Cellular processes and signaling:Metabolism:Poorly characterized" 220 "Energy production and conversion:Purine nucleoside phosphorylase:NhaP-type Na+/H+ and K+/H+ antiporters:Predicted esterase:Transcriptional regulator:Predicted phosphoesterase:Glutathione S-transferase:Signal transduction histidine kinase:Glycine/D-amino acid oxidases (deaminating):Lactate dehydrogenase and related dehydrogenases:3'-Phosphoadenosine 5'-phosphosulfate (PAPS) 3'-phosphatase:Transcriptional regulator:Disulfide bond formation protein DsbB:Phosphatidylserine/phosphatidylglycerophosphate/cardiolipin synthases and related enzymes:Beta-lactamase class C and other penicillin binding proteins:Uncharacterized conserved protein:N-terminal domain of molybdenum-binding protein:Lysophospholipase:Uncharacterized conserved protein:Predicted ATPase (AAA+ superfamily):Arabinose efflux permease:Uncharacterized protein involved in cysteine biosynthesis:Uncharacterized protein conserved in bacteria:Predicted hydrolase of the alpha/beta-hydrolase fold:ABC-type molybdate transport system, permease component:Kef-type K+ transport system, predicted NAD-binding component:Amino acid transport and metabolism:Nucleotide transport and metabolism:Carbohydrate transport and metabolism:Coenzyme transport and metabolism:Lipid transport and metabolism:Transcription:Posttranslational modification, protein turnover, chaperones:Inorganic ion transport and metabolism:Pentose phosphate pathway:Cysteine and methionine metabolism:Thiamine metabolism:Metabolic pathways:Microbial metabolism in diverse environments:ABC transporters:Two-component system:General function prediction only:Function unknown:Signal transduction mechanisms:yfcE:ModE_repress:bisphos_cysQ:MTAP:modB_ABC:thiamin_ThiO:TMPT_Se_Te:Defense mechanisms:Thiamine:Biosynthesis of cofactors, prosthetic groups, and carriers:Enzymes of unknown specificity:Unknown function:Anions:Transport and binding proteins:Other:Regulatory functions:Salvage of nucleosides and nucleotides:Purines, pyrimidines, nucleosides, and nucleotides:Sulfur metabolism:Central intermediary metabolism:Metabolism:Metabolism:Global:Signal Transduction:Membrane Transport:Environmental Information Processing:Metabolism of Cofactors and Vitamins:Amino Acid Metabolism:Carbohydrate Metabolism:Poorly characterized:Metabolism:Cellular processes and signaling:Information storage and processing" 221 "Sulfate permease and related transporters (MFS superfamily):Mannose-1-phosphate guanylyltransferase:Predicted UDP-glucose 6-dehydrogenase:Predicted membrane protein involved in D-alanine export:Predicted acyltransferases:Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains:SH3 domain protein:Uncharacterized protein conserved in bacteria:Uncharacterized protein conserved in bacteria:Signal transduction histidine kinase:Lipid transport and metabolism:Cell wall/membrane/envelope biogenesis:Inorganic ion transport and metabolism:Fructose and mannose metabolism:Amino sugar and nucleotide sugar metabolism:Metabolic pathways:Biosynthesis of secondary metabolites:Two-component system:Function unknown:Signal transduction mechanisms:sensory_box:GMP_PMI:NDP-sugDHase:para_beta_helix:Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides:Carbohydrate Metabolism:Environmental Information Processing:Signal Transduction:Global:Metabolism:Regulatory functions:Small molecule interactions:Cell envelope:Metabolism:Cellular processes and signaling:Metabolism:Poorly characterized" 222 "Sulfite reductase, beta subunit (hemoprotein):3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase and related enzymes:Predicted flavoprotein:Peroxiredoxin:ABC-type sulfate transport system, permease component:Predicted permeases:ABC-type amino acid transport/signal transduction systems, periplasmic component/domain:Cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes:ABC-type sulfate/molybdate transport systems, ATPase component:Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain:ABC-type metal ion transport system, periplasmic component/surface antigen:ABC-type sulfate transport system, periplasmic component:GTPases - Sulfate adenylate transferase subunit 1:Predicted esterase of the alpha/beta hydrolase fold:Uncharacterized protein conserved in bacteria:ABC-type sulfate transport system, permease component:Phenylpropionate dioxygenase and related ring-hydroxylating dioxygenases, large terminal subunit:Uncharacterized small protein:Amino acid transport and metabolism:Coenzyme transport and metabolism:Transcription:Posttranslational modification, protein turnover, chaperones:Inorganic ion transport and metabolism:Purine metabolism:Selenocompound metabolism:Thiamine metabolism:Porphyrin and chlorophyll metabolism:Sulfur metabolism:Metabolic pathways:Microbial metabolism in diverse environments:ABC transporters:Sulfur relay system:General function prediction only:Function unknown:Signal transduction mechanisms:small_GTP:cysH:3a0106s01:3a0106s02:3a0106s03:CysD:FMN_reduc_SsuE:Cellular processes and signaling:Information storage and processing:General:Unknown function:Anions:Transport and binding proteins:Sulfur metabolism:Central intermediary metabolism:Metabolism:Metabolism:Global:Membrane Transport:Environmental Information Processing:Folding Sorting and Degradation:Genetic Information Processing:Metabolism of Cofactors and Vitamins:Metabolism of Other Amino Acids:Nucleotide Metabolism:Poorly characterized:Energy Metabolism:Metabolism" 223 "Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase:N-formylmethionyl-tRNA deformylase:Phosphoheptose isomerase:FKBP-type peptidyl-prolyl cis-trans isomerases 1:Protease subunit of ATP-dependent Clp proteases:DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog:DNA-directed RNA polymerase, subunit K/omega:Uncharacterized protein conserved in bacteria:Preprotein translocase subunit SecB:Methylase involved in ubiquinone/menaquinone biosynthesis:Predicted periplasmic or secreted lipoprotein:Amino acid transport and metabolism:Carbohydrate transport and metabolism:Coenzyme transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:Posttranslational modification, protein turnover, chaperones:Ubiquinone and other terpenoid-quinone biosynthesis:Purine metabolism:Pyrimidine metabolism:Valine leucine and isoleucine degradation:Valine leucine and isoleucine biosynthesis:Lipopolysaccharide biosynthesis:Pantothenate and CoA biosynthesis:Aminoacyl-tRNA biosynthesis:Metabolic pathways:Biosynthesis of secondary metabolites:Two-component system:RNA polymerase:Protein export:Bacterial secretion system:General function prediction only:Function unknown:pept_deformyl:clpP:rpoZ:secB:ilvE_I:MenG_MenH_UbiE:rpoN_sigma:outer_YhbN_LptA:Intracellular trafficking, secretion, and vesicular transport:Amino acid biosynthesis:Nucleotide Metabolism:Amino Acid Metabolism:Glycan Biosynthesis and Metabolism:Metabolism of Cofactors and Vitamins:Genetic Information Processing:Transcription:Translation:Folding Sorting and Degradation:Environmental Information Processing:Membrane Transport:Signal Transduction:Global:Metabolism:Transcription:DNA-dependent RNA polymerase:Transcription factors:Protein fate:Protein and peptide secretion and trafficking:Degradation of proteins, peptides, and glycopeptides:Protein modification and repair:Transport and binding proteins:Other:Metabolism:Pyruvate family:Biosynthesis of cofactors, prosthetic groups, and carriers:Menaquinone and ubiquinone:Information storage and processing:Cellular processes and signaling:Metabolism:Poorly characterized" 224 "Energy production and conversion:Acetyl-CoA acetyltransferase:Glutamate 5-kinase:Uncharacterized conserved protein:Predicted epimerase, PhzC/PhzF homolog:Peroxiredoxin:Selenophosphate synthase:Membrane-fusion protein:Putative effector of murein hydrolase:Uncharacterized protein conserved in bacteria:Putative effector of murein hydrolase LrgA:DnaK suppressor protein:Transcriptional regulators:Uncharacterized protein, possibly involved in aromatic compounds catabolism:Predicted ATPase:Cytochrome B561:Alkyl hydroperoxide reductase, large subunit:Uncharacterized conserved small protein:Amino acid transport and metabolism:Lipid transport and metabolism:Transcription:Cell wall/membrane/envelope biogenesis:Posttranslational modification, protein turnover, chaperones:Fatty acid metabolism:Synthesis and degradation of ketone bodies:Valine leucine and isoleucine degradation:Lysine degradation:Arginine and proline metabolism:Benzoate degradation:Tryptophan metabolism:Selenocompound metabolism:Pyruvate metabolism:Glyoxylate and dicarboxylate metabolism:Propanoate metabolism:Butanoate metabolism:Carbon fixation pathways in prokaryotes:Terpenoid backbone biosynthesis:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:Two-component system:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:Function unknown:Signal transduction mechanisms:selD:PhzF_family:proB:RND_mfp:AcCoA-C-Actrans:C4_traR_proteo:AhpC:AhpF:tRNA_sel_U_synt:YhgI_GntY:Biosynthesis of cofactors, prosthetic groups, and carriers:Carbohydrate Metabolism:Energy Metabolism:Lipid Metabolism:Amino Acid Metabolism:Metabolism of Other Amino Acids:Metabolism of Terpenoids and Polyketides:Xenobiotics Biodegradation and Metabolism:Environmental Information Processing:Signal Transduction:Global:Metabolism:Fatty acid and phospholipid metabolism:Other:Protein synthesis:tRNA and rRNA base modification:Transport and binding proteins:Unknown substrate:Cellular processes:Toxin production and resistance:Adaptations to atypical conditions:Mobile and extrachromosomal element functions:Prophage functions:Amino acid biosynthesis:Glutamate family:Metabolism:Other:Information storage and processing:Cellular processes and signaling:Metabolism:Poorly characterized" 225 "Energy production and conversion:Arginyl-tRNA synthetase:Dihydroorotase and related cyclic amidohydrolases:Fructose-1,6-bisphosphatase:Pyridoxamine-phosphate oxidase:Predicted esterase:Di- and tricarboxylate transporters:Aspartate carbamoyltransferase, catalytic chain:NADPH:quinone reductase and related Zn-dependent oxidoreductases:cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases:Spermidine/putrescine-binding periplasmic protein:ABC-type multidrug transport system, permease component:ATPase components of various ABC-type transport systems, contain duplicated ATPase:Uncharacterized conserved protein:Bacterioferritin (cytochrome b1):Predicted transporter component:Uncharacterized conserved protein:Predicted carboxypeptidase:Cell division protein:Cytochrome c:Signal transduction histidine kinase, nitrate/nitrite-specific:Predicted phosphoadenosine phosphosulfate sulfotransferase:Cell cycle control, cell division, chromosome partitioning:Amino acid transport and metabolism:Nucleotide transport and metabolism:Carbohydrate transport and metabolism:Coenzyme transport and metabolism:Translation, ribosomal structure and biogenesis:Inorganic ion transport and metabolism:Glycolysis / Gluconeogenesis:Pentose phosphate pathway:Fructose and mannose metabolism:Pyrimidine metabolism:Alanine aspartate and glutamate metabolism:Methane metabolism:Vitamin B6 metabolism:Aminoacyl-tRNA biosynthesis:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:ABC transporters:Two-component system:General function prediction only:Function unknown:Signal transduction mechanisms:argS:pdxH:asp_carb_tr:bfr:pyrC_multi:adh_fam_1:Defense mechanisms:Metabolism:Poorly characterized:Metabolism:Cellular processes and signaling:Information storage and processing:Pyridoxine:Biosynthesis of cofactors, prosthetic groups, and carriers:Cations and iron carrying compounds:Transport and binding proteins:tRNA aminoacylation:Protein synthesis:Pyrimidine ribonucleotide biosynthesis:Purines, pyrimidines, nucleosides, and nucleotides:Fermentation:Energy metabolism:Metabolism:Global:Signal Transduction:Membrane Transport:Environmental Information Processing:Translation:Genetic Information Processing:Metabolism of Cofactors and Vitamins:Amino Acid Metabolism:Nucleotide Metabolism:Energy Metabolism:Carbohydrate Metabolism" 226 "EMAP domain:Signal transduction histidine kinase:Methyl-accepting chemotaxis protein:Threonine dehydrogenase and related Zn-dependent dehydrogenases:Hemolysins and related proteins containing CBS domains:Cation transport ATPase:Arabinose efflux permease:Signal transduction histidine kinase regulating C4-dicarboxylate transport system:Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain:Amino acid transport and metabolism:Carbohydrate transport and metabolism:Transcription:Cell motility:Inorganic ion transport and metabolism:Two-component system:Bacterial chemotaxis:General function prediction only:Signal transduction mechanisms:TIGR00003:sensory_box:efflux_Bcr_CflA:cztS_silS_copS:chap_CsaA:Cellular processes and signaling:Signal Transduction:Cellular Processes:Cell Motility:Regulatory functions:Small molecule interactions:Protein fate:Protein and peptide secretion and trafficking:Transport and binding proteins:Cations and iron carrying compounds:Information storage and processing:Environmental Information Processing:Metabolism:Poorly characterized" 227 "Energy production and conversion:Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit:Acetyl-CoA acetyltransferase:Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component, and related enzymes:Enoyl-CoA hydratase/carnithine racemase:Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit:Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes:Acyl-CoA dehydrogenases:Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta):Lipid transport and metabolism:Glycolysis / Gluconeogenesis:Citrate cycle (TCA cycle):Fatty acid metabolism:Synthesis and degradation of ketone bodies:Glycine serine and threonine metabolism:Valine leucine and isoleucine degradation:Geraniol degradation:Lysine degradation:Benzoate degradation:Tryptophan metabolism:beta-Alanine metabolism:Pyruvate metabolism:Naphthalene degradation:Aminobenzoate degradation:Glyoxylate and dicarboxylate metabolism:Propanoate metabolism:Butanoate metabolism:Carbon fixation pathways in prokaryotes:Terpenoid backbone biosynthesis:Limonene and pinene degradation:Caprolactam degradation:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:Two-component system:lipoamide_DH:AcCoA-C-Actrans:Lipid Metabolism:Energy Metabolism:Metabolism:Xenobiotics Biodegradation and Metabolism:Carbohydrate Metabolism:Environmental Information Processing:Signal Transduction:Global:Metabolism:Fatty acid and phospholipid metabolism:Other:Metabolism:Metabolism of Terpenoids and Polyketides:Metabolism of Other Amino Acids:Amino Acid Metabolism" 228 "Diaminopimelate decarboxylase:Methionine aminopeptidase:Phosphoribosyl-ATP pyrophosphohydrolase:Dihydrodipicolinate synthase/N-acetylneuraminate lyase:Predicted acid phosphatase:Enoyl-CoA hydratase/carnithine racemase:Predicted transcriptional regulator, consists of a Zn-ribbon and ATP-cone domains:Pyrimidine reductase, riboflavin biosynthesis:Protein-L-isoaspartate carboxylmethyltransferase:Septum formation inhibitor-activating ATPase:Small protein A (tmRNA-binding):Uncharacterized protein conserved in bacteria:Uncharacterized protein conserved in bacteria:Predicted small periplasmic lipoprotein:Cell cycle control, cell division, chromosome partitioning:Amino acid transport and metabolism:Coenzyme transport and metabolism:Lipid transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:Cell wall/membrane/envelope biogenesis:Cell motility:Posttranslational modification, protein turnover, chaperones:Fatty acid metabolism:Purine metabolism:Pyrimidine metabolism:Valine leucine and isoleucine degradation:Geraniol degradation:Lysine biosynthesis:Lysine degradation:Histidine metabolism:Benzoate degradation:Tryptophan metabolism:beta-Alanine metabolism:Aminobenzoate degradation:Propanoate metabolism:Butanoate metabolism:Riboflavin metabolism:Nicotinate and nicotinamide metabolism:Limonene and pinene degradation:Caprolactam degradation:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:General function prediction only:Function unknown:pimt:surE:ribD_Cterm:TIGR00244:met_pdase_I:dapA:lysA:minD_bact:histidine_hisI:Poorly characterized:Metabolism:Cellular processes and signaling:Information storage and processing:Histidine family:Aspartate family:Amino acid biosynthesis:Adaptations to atypical conditions:Cell division:Cellular processes:Protein modification and repair:Protein fate:DNA interactions:Regulatory functions:Metabolism:Metabolism:Global:Xenobiotics Biodegradation and Metabolism:Metabolism of Terpenoids and Polyketides:Metabolism of Cofactors and Vitamins:Metabolism of Other Amino Acids:Amino Acid Metabolism:Nucleotide Metabolism:Lipid Metabolism:Carbohydrate Metabolism" 229 "3-methyladenine DNA glycosylase/8-oxoguanine DNA glycosylase:5-formyltetrahydrofolate cyclo-ligase:Methylated DNA-protein cysteine methyltransferase:Transcriptional regulator:2-keto-3-deoxy-6-phosphogluconate aldolase:Predicted thioesterase:16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases:Predicted membrane protein:Amidases related to nicotinamidase:Uncharacterized protein conserved in bacteria:Predicted metal-dependent hydrolase:Uroporphyrinogen-III synthase:Predicted pyrophosphatase:Transcriptional regulators:Uncharacterized protein, possibly involved in aromatic compounds catabolism:2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase:Uncharacterized protein with SCP/PR1 domains:Membrane-bound lytic murein transglycosylase:Protein involved in catabolism of external DNA:Negative regulator of beta-lactamase expression:Uncharacterized protein conserved in bacteria:Predicted membrane protein:Metal-dependent hydrolase:Uncharacterized conserved small protein:Carbohydrate transport and metabolism:Coenzyme transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:Replication, recombination and repair:Cell wall/membrane/envelope biogenesis:Pentose phosphate pathway:Pentose and glucuronate interconversions:Arginine and proline metabolism:Glyoxylate and dicarboxylate metabolism:One carbon pool by folate:Porphyrin and chlorophyll metabolism:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:Base excision repair:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:Function unknown:TIGR00046:TIGR00093:ogt:yihY_not_rbn:eda:MTHFS_bact:Defense mechanisms:Unknown function:tRNA and rRNA base modification:Protein synthesis:DNA replication, recombination, and repair:DNA metabolism:Entner-Doudoroff:Energy metabolism:One-carbon metabolism:Central intermediary metabolism:Metabolism:Metabolism:Global:Replication and Repair:Genetic Information Processing:Metabolism of Cofactors and Vitamins:Amino Acid Metabolism:Carbohydrate Metabolism:Poorly characterized:Metabolism:Cellular processes and signaling:Information storage and processing:General" 230 "Translation initiation factor 1 (eIF-1/SUI1) and related proteins:Superfamily I DNA and RNA helicases:Molecular chaperone:Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family:ATPase components of ABC transporters with duplicated ATPase domains:Metal-dependent proteases with possible chaperone activity:7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase:Predicted permease:Predicted flavoproteins:Xanthine/uracil permeases:Uncharacterized conserved protein:Uncharacterized protein conserved in bacteria:ABC-type spermidine/putrescine transport systems, ATPase components:Amino acid transport and metabolism:Nucleotide transport and metabolism:Carbohydrate transport and metabolism:Coenzyme transport and metabolism:Translation, ribosomal structure and biogenesis:Replication, recombination and repair:Posttranslational modification, protein turnover, chaperones:Streptomycin biosynthesis:Inositol phosphate metabolism:Folate biosynthesis:Metabolic pathways:Biosynthesis of secondary metabolites:ABC transporters:General function prediction only:Function unknown:TIGR00275:gcp_kae1:ncs2:rep:SUI1_rel:potA:folK:Poorly characterized:Carbohydrate Metabolism:Metabolism of Cofactors and Vitamins:Biosynthesis of Other Secondary Metabolites:Environmental Information Processing:Membrane Transport:Global:Metabolism:DNA metabolism:DNA replication, recombination, and repair:Protein synthesis:Translation factors:Protein fate:Degradation of proteins, peptides, and glycopeptides:Transport and binding proteins:Amino acids, peptides and amines:Nucleosides, purines and pyrimidines:Unknown function:Enzymes of unknown specificity:Biosynthesis of cofactors, prosthetic groups, and carriers:Folic acid:Information storage and processing:Cellular processes and signaling:Metabolism:Metabolism" 231 "FOG: TPR repeat, SEL1 subfamily:FOG: HPt domain:Membrane protein involved in the export of O-antigen and teichoic acid:Transposase and inactivated derivatives:Uncharacterized protein conserved in bacteria:Transposase and inactivated derivatives:P pilus assembly protein, chaperone PapD:P pilus assembly protein, porin PapC:Lipid A core - O-antigen ligase and related enzymes:P pilus assembly protein, pilin FimA:Replication, recombination and repair:Cell wall/membrane/envelope biogenesis:Cell motility:General function prediction only:Function unknown:Signal transduction mechanisms:Intracellular trafficking, secretion, and vesicular transport:Poorly characterized:Cellular processes and signaling:Information storage and processing" 232 "Energy production and conversion:Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain:23S rRNA methylase:Predicted methyltransferases:Translation initiation factor 1 (IF-1):FKBP-type peptidyl-prolyl cis-trans isomerases 1:RNase PH:GTP cyclohydrolase II:Predicted hydrolase (HAD superfamily):Predicted RNA-binding protein containing KH domain, possibly ribosomal protein:Uncharacterized protein conserved in bacteria:Uncharacterized protein conserved in bacteria:Predicted NADH:ubiquinone oxidoreductase, subunit RnfA:Coenzyme transport and metabolism:Translation, ribosomal structure and biogenesis:Posttranslational modification, protein turnover, chaperones:Riboflavin metabolism:Metabolic pathways:General function prediction only:Function unknown:infA:TIGR00096:RNA_bind_YhbY:ribA:HAD-SF-IA-v3:rnfA:RNasePH:Poorly characterized:Information storage and processing:Riboflavin, FMN, and FAD:Biosynthesis of cofactors, prosthetic groups, and carriers:General:Enzymes of unknown specificity:Unknown function:Translation factors:Protein synthesis:RNA processing:Transcription:Electron transport:Energy metabolism:Metabolism:Metabolism:Global:Cellular processes and signaling:Metabolism of Cofactors and Vitamins:Metabolism" 233 "Predicted Fe-S oxidoreductases:Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases:Putative intracellular protease/amidase:Metal-dependent hydrolases of the beta-lactamase superfamily I:Acyl-CoA dehydrogenases:Ribosome modulation factor:Uncharacterized conserved protein:Pyrroloquinoline quinone (Coenzyme PQQ) biosynthesis protein C:Nucleotide transport and metabolism:Carbohydrate transport and metabolism:Coenzyme transport and metabolism:Lipid transport and metabolism:Translation, ribosomal structure and biogenesis:Fatty acid metabolism:Metabolic pathways:General function prediction only:Function unknown:PQQ_syn_pqqA:PQQ_syn_pqqB:PQQ_syn_pqqE:PQQ_syn_pqqC:PQQ_PqqD:Poorly characterized:Lipid Metabolism:Global:Metabolism:Biosynthesis of cofactors, prosthetic groups, and carriers:Other:Information storage and processing:Metabolism:Metabolism" 234 "Branched-chain amino acid ABC-type transport system, permease components:Spermidine/putrescine-binding periplasmic protein:Catalase:ABC-type amino acid transport system, permease component:ABC-type amino acid transport/signal transduction systems, periplasmic component/domain:ABC-type uncharacterized transport system, ATPase component:ABC-type spermidine/putrescine transport system, permease component I:ABC-type spermidine/putrescine transport system, permease component II:Carbon starvation protein, predicted membrane protein:Long-chain fatty acid transport protein:Uncharacterized small protein:ABC-type uncharacterized transport system, periplasmic component:ABC-type phosphate/phosphonate transport system, periplasmic component:ABC-type spermidine/putrescine transport systems, ATPase components:ABC-type uncharacterized transport system, permease component:ABC-type arginine/histidine transport system, permease component:ABC-type arginine transport system, permease component:ABC-type histidine transport system, ATPase component:Amino acid transport and metabolism:Lipid transport and metabolism:Inorganic ion transport and metabolism:ABC transporters:General function prediction only:Function unknown:Signal transduction mechanisms:3A0109s03R:potA:HEQRo_perm_3TM:Environmental Information Processing:Poorly characterized:Metabolism:Cellular processes and signaling:Anions:Amino acids, peptides and amines:Transport and binding proteins:Membrane Transport" 235 "FKBP-type peptidyl-prolyl cis-trans isomerases 1:Transcriptional regulator:Cytosine/adenosine deaminases:ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components:ABC-type metal ion transport system, ATPase component:Predicted membrane protein:Outer membrane receptor proteins, mostly Fe transport:Cytosine/uracil/thiamine/allantoin permeases:Acyl-CoA dehydrogenases:ABC-type metal ion transport system, permease component:Cation transport ATPase:Putative NADPH-quinone reductase (modulator of drug activity B):Cyanate permease:Uncharacterized protein conserved in bacteria:P pilus assembly protein, pilin FimA:Uncharacterized conserved protein:ABC-type arginine/histidine transport system, permease component:Amino acid transport and metabolism:Nucleotide transport and metabolism:Coenzyme transport and metabolism:Lipid transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:Cell motility:Posttranslational modification, protein turnover, chaperones:Inorganic ion transport and metabolism:ABC transporters:General function prediction only:Function unknown:ATPase_P-type:HEQRo_perm_3TM:sulfur_SfnB:Intracellular trafficking, secretion, and vesicular transport:Membrane Transport:Environmental Information Processing:Poorly characterized:Metabolism:Cellular processes and signaling:Information storage and processing:Amino acids, peptides and amines:Transport and binding proteins:Sulfur metabolism:Central intermediary metabolism" 236 "Ammonia permease:Mg-dependent DNase:Predicted amidohydrolase:Thioredoxin reductase:Transcriptional regulator:Methionine synthase II (cobalamin-independent):Phosphoenolpyruvate-protein kinase (PTS system EI component in bacteria):Fructose-1-phosphate kinase and related fructose-6-phosphate kinase (PfkB):Phosphotransferase system, fructose-specific IIC component:Oxygen-sensitive ribonucleoside-triphosphate reductase:Predicted transcriptional regulator:Sulfite oxidase and related enzymes:3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases:ABC-type proline/glycine betaine transport systems, periplasmic components:AraC-type DNA-binding domain-containing proteins:Xanthine/uracil permeases:Putative glycerate kinase:DNA-binding HTH domain-containing proteins:Cyanate permease:Arabinose efflux permease:Uncharacterized conserved protein:Uncharacterized protein conserved in bacteria:Ureidoglycolate hydrolase:Transcriptional activator of acetoin/glycerol metabolism:Hydroxypyruvate isomerase:Allantoicase:Amino acid transport and metabolism:Nucleotide transport and metabolism:Carbohydrate transport and metabolism:Lipid transport and metabolism:Transcription:Replication, recombination and repair:Posttranslational modification, protein turnover, chaperones:Inorganic ion transport and metabolism:Fructose and mannose metabolism:Purine metabolism:Pyrimidine metabolism:Glycine serine and threonine metabolism:Cysteine and methionine metabolism:Glyoxylate and dicarboxylate metabolism:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:ABC transporters:Phosphotransferase system (PTS):Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:Function unknown:ncs2:FRU:amt:CynX:PTS_HPr_family:met_syn_B12ind:tartro_sem_red:NrdD:allantoicase:1-PFK:OH-pyruv-isom:ABC_choline_bnd:Signal transduction:Carbohydrate Metabolism:Nucleotide Metabolism:Amino Acid Metabolism:Environmental Information Processing:Membrane Transport:Global:Metabolism:Energy metabolism:Other:Purines, pyrimidines, nucleosides, and nucleotides:2'-Deoxyribonucleotide metabolism:Transport and binding proteins:Amino acids, peptides and amines:Cations and iron carrying compounds:Nucleosides, purines and pyrimidines:Other:Amino acid biosynthesis:Aspartate family:Metabolism:PTS:Information storage and processing:Cellular processes and signaling:Metabolism:Poorly characterized" 237 "Fructose/tagatose bisphosphate aldolase:Membrane protease subunits, stomatin/prohibitin homologs:Biotin carboxylase:Pyruvate kinase:Biotin carboxyl carrier protein:Superfamily II DNA and RNA helicases:cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases:ABC-type sulfate transport system, periplasmic component:Uncharacterized protein conserved in bacteria:Periplasmic glucans biosynthesis protein:Uncharacterized protein conserved in bacteria:Uncharacterized protein conserved in bacteria:Carbohydrate transport and metabolism:Lipid transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:Replication, recombination and repair:Posttranslational modification, protein turnover, chaperones:Inorganic ion transport and metabolism:Glycolysis / Gluconeogenesis:Pentose phosphate pathway:Fructose and mannose metabolism:Fatty acid biosynthesis:Purine metabolism:Pyruvate metabolism:Propanoate metabolism:Methane metabolism:Carbon fixation pathways in prokaryotes:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:ABC transporters:Two-component system:RNA degradation:Function unknown:Signal transduction mechanisms:cbbA:accC:BCCP:3a0106s03:pyruv_kin:hflC:Cellular processes and signaling:Metabolism:Poorly characterized:Energy metabolism:Metabolism:Global:Signal Transduction:Membrane Transport:Environmental Information Processing:Metabolism:Folding Sorting and Degradation:Genetic Information Processing:Nucleotide Metabolism:Lipid Metabolism:Energy Metabolism:Glycolysis/gluconeogenesis:Carbohydrate Metabolism:Fatty acid and phospholipid metabolism:Biosynthesis:Regulatory functions:Protein interactions:Transport and binding proteins:Anions:Information storage and processing" 238 "Energy production and conversion:4-aminobutyrate aminotransferase and related aminotransferases:Adenosylmethionine-8-amino-7-oxononanoate aminotransferase:Glutamine synthetase:Putative translation initiation inhibitor, yjgF family:ATPase components of ABC transporters with duplicated ATPase domains:GMP synthase - Glutamine amidotransferase domain:Glycine/D-amino acid oxidases (deaminating):DNA-binding ferritin-like protein (oxidative damage protectant):NAD-dependent aldehyde dehydrogenases:Predicted transcriptional regulators:Beta-propeller domains of methanol dehydrogenase type:Uncharacterized conserved protein:Predicted glutamine amidotransferases:Uncharacterized protein conserved in bacteria:Uncharacterized protein involved in an early stage of isoprenoid biosynthesis:Amino acid transport and metabolism:Nucleotide transport and metabolism:Coenzyme transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:Inorganic ion transport and metabolism:Alanine aspartate and glutamate metabolism:Valine leucine and isoleucine degradation:Lysine degradation:Arginine and proline metabolism:Phenylalanine metabolism:beta-Alanine metabolism:Propanoate metabolism:Nitrogen metabolism:Metabolic pathways:Microbial metabolism in diverse environments:Two-component system:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:Function unknown:GABAtrnsam:SSADH:ABC_ABC_ChvD:Amino Acid Metabolism:Energy Metabolism:Poorly characterized:Carbohydrate Metabolism:Metabolism:Information storage and processing:Other:Central intermediary metabolism:Metabolism:Global:Signal Transduction:Environmental Information Processing:Metabolism:Metabolism of Other Amino Acids" 239 "Energy production and conversion:Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II:Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases:ABC-type sugar transport system, permease component:Amino acid transporters:ABC-type amino acid transport/signal transduction systems, periplasmic component/domain:NAD-dependent aldehyde dehydrogenases:Gamma-aminobutyrate permease and related permeases:ABC-type sugar transport systems, permease components:Alcohol dehydrogenase, class IV:ABC-type sugar transport system, periplasmic component:Short chain fatty acids transporter:Sugar phosphate permease:Choline dehydrogenase and related flavoproteins:ATP-dependent transcriptional regulator:Predicted membrane protein:Carbohydrate-selective porin:ABC-type sugar transport systems, ATPase components:Predicted symporter:Ethanolamine ammonia-lyase, small subunit:Ethanolamine ammonia-lyase, large subunit:Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain:Amino acid transport and metabolism:Carbohydrate transport and metabolism:Lipid transport and metabolism:Transcription:Cell wall/membrane/envelope biogenesis:Glycolysis / Gluconeogenesis:Pentose and glucuronate interconversions:Ascorbate and aldarate metabolism:Fatty acid metabolism:Glycine serine and threonine metabolism:Valine leucine and isoleucine degradation:Lysine degradation:Arginine and proline metabolism:Histidine metabolism:Tryptophan metabolism:beta-Alanine metabolism:Glycerolipid metabolism:Glycerophospholipid metabolism:Pyruvate metabolism:Chloroalkane and chloroalkene degradation:Propanoate metabolism:Methane metabolism:Carbon fixation pathways in prokaryotes:Limonene and pinene degradation:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:Two-component system:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:Function unknown:Signal transduction mechanisms:sss:2A0305:GABAperm:Ac_CoA_lig_AcsA:Amino Acid Metabolism:Lipid Metabolism:Metabolism:Energy Metabolism:Metabolism:Carbohydrate Metabolism:Poorly characterized:Cellular processes and signaling:Information storage and processing:Cations and iron carrying compounds:Amino acids, peptides and amines:Transport and binding proteins:Metabolism:Global:Signal Transduction:Environmental Information Processing:Xenobiotics Biodegradation and Metabolism:Metabolism of Terpenoids and Polyketides:Metabolism of Other Amino Acids" 240 "Energy production and conversion:Arginase/agmatinase/formimionoglutamate hydrolase, arginase family:Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase]:Shikimate 5-dehydrogenase:FAD/FMN-containing dehydrogenases:Gamma-glutamyltransferase:Na+/proline symporter:Glutathione S-transferase:Collagenase and related proteases:Urease accessory protein UreF:L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases:Purine-cytosine permease and related proteins:Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL homologs:L-lactate permease:Glycerate kinase:Cytochrome c, mono- and diheme variants:Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS/CutS homologs:Predicted membrane protein:Urease accessory protein UreE:H+/gluconate symporter and related permeases:Uncharacterized protein conserved in bacteria:Uncharacterized protein conserved in bacteria:Predicted membrane protein:Ketosteroid isomerase homolog:Amino acid transport and metabolism:Nucleotide transport and metabolism:Carbohydrate transport and metabolism:Coenzyme transport and metabolism:Posttranslational modification, protein turnover, chaperones:Glycine serine and threonine metabolism:Valine leucine and isoleucine biosynthesis:Arginine and proline metabolism:Phenylalanine tyrosine and tryptophan biosynthesis:Taurine and hypotaurine metabolism:Selenocompound metabolism:Cyanoamino acid metabolism:Glutathione metabolism:Glycerolipid metabolism:Arachidonic acid metabolism:Pyruvate metabolism:Glyoxylate and dicarboxylate metabolism:Butanoate metabolism:C5-Branched dibasic acid metabolism:Methane metabolism:Pantothenate and CoA biosynthesis:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:General function prediction only:Function unknown:TIGR00045:aroE:lctP:agmatinase:Energy Metabolism:Cellular processes and signaling:Carbohydrate Metabolism:Metabolism:Poorly characterized:Aromatic amino acid family:Amino acid biosynthesis:Carbohydrates, organic alcohols, and acids:Transport and binding proteins:Other:Energy metabolism:Metabolism:Global:Metabolism of Cofactors and Vitamins:Metabolism of Other Amino Acids:Amino Acid Metabolism:Metabolism:Lipid Metabolism" 241 "Predicted sugar phosphatases of the HAD superfamily:Spermidine/putrescine-binding periplasmic protein:ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components:Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain:Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs:Amidases related to nicotinamidase:Beta-lactamase class C and other penicillin binding proteins:Uncharacterized protein, possibly involved in aromatic compounds catabolism:Osmosensitive K+ channel histidine kinase:Predicted membrane protein:Beta-lactamase class D:ABC-type uncharacterized transport system involved in gliding motility, auxiliary component:Phospholipase/lecithinase/hemolysin:Predicted periplasmic ligand-binding sensor domain:Prophage antirepressor:Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains:Amino acid transport and metabolism:Carbohydrate transport and metabolism:Lipid transport and metabolism:Transcription:Cell motility:Inorganic ion transport and metabolism:Penicillin and cephalosporin biosynthesis:Biosynthesis of siderophore group nonribosomal peptides:Biosynthesis of secondary metabolites:ABC transporters:Two-component system:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:Function unknown:Signal transduction mechanisms:sensory_box:HAD-SF-IIA-hyp4:SsuA_fam:Defense mechanisms:Metabolism:Poorly characterized:Metabolism:Cellular processes and signaling:Information storage and processing:Other:Transport and binding proteins:Small molecule interactions:Regulatory functions:Metabolism:Global:Signal Transduction:Membrane Transport:Environmental Information Processing:Biosynthesis of Other Secondary Metabolites:Metabolism of Terpenoids and Polyketides" 242 "ATPases involved in chromosome partitioning:Chemotaxis protein histidine kinase and related kinases:FOG: CheY-like receiver:Chemotaxis signal transduction protein:DNA-directed RNA polymerase specialized sigma subunit:ATPases involved in chromosome partitioning:Flagellar biosynthesis/type III secretory pathway protein:Flagellar motor switch protein:Flagellar basal-body P-ring protein:Flagellar hook protein FlgE:Flagellar basal body L-ring protein:Chemotaxis response regulator containing a CheY-like receiver domain and a methylesterase domain:Chemotaxis protein:Rod binding protein:Flagellar basal body rod protein:Cell cycle control, cell division, chromosome partitioning:Transcription:Cell wall/membrane/envelope biogenesis:Cell motility:Posttranslational modification, protein turnover, chaperones:Two-component system:Bacterial chemotaxis:Flagellar assembly:RNA polymerase:Signal transduction mechanisms:fliG:FliA_WhiG:flgG_G_neg:flagell_FlgJ:FlgEFG_subfam:Intracellular trafficking, secretion, and vesicular transport:Transcription:Information storage and processing:Chemotaxis and motility:Genetic Information Processing:Cellular processes:Cell Motility:Cellular Processes:Signal Transduction:Environmental Information Processing:Cellular processes and signaling" 243 "Glutamate-1-semialdehyde aminotransferase:Glutamine synthetase:Putative translation initiation inhibitor, yjgF family:Uncharacterized conserved protein:Selenocysteine lyase:Transcriptional regulator:Signal transduction histidine kinase:Predicted xylanase/chitin deacetylase:Predicted transcriptional regulators:Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases):Predicted nucleoside-diphosphate sugar epimerase:Acyl-CoA hydrolase:Predicted transcriptional regulators:Transcriptional regulators:Transcriptional regulators:Protein implicated in iron transport, frataxin homolog:Transthyretin-like protein:Transcriptional antiterminator:Amino acid transport and metabolism:Carbohydrate transport and metabolism:Coenzyme transport and metabolism:Lipid transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:Inorganic ion transport and metabolism:Fatty acid biosynthesis:Purine metabolism:Alanine aspartate and glutamate metabolism:Arginine and proline metabolism:Porphyrin and chlorophyll metabolism:Nitrogen metabolism:Biosynthesis of unsaturated fatty acids:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:Two-component system:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:Function unknown:Signal transduction mechanisms:TIGR00049:yfcH:CadR-PbrR:hdxy_isourate:uraD_N-term-dom:FeS_CyaY:Metabolism:Cellular processes and signaling:Information storage and processing:Other:Biosynthesis of cofactors, prosthetic groups, and carriers:Conserved:Hypothetical proteins:Other:Purines, pyrimidines, nucleosides, and nucleotides:Metabolism:Metabolism:Global:Signal Transduction:Environmental Information Processing:Metabolism of Cofactors and Vitamins:Amino Acid Metabolism:Nucleotide Metabolism:Lipid Metabolism:Poorly characterized:Energy Metabolism" 244 "Energy production and conversion:Glutamate-1-semialdehyde aminotransferase:Asp-tRNAAsn/Glu-tRNAGln amidotransferase B subunit (PET112 homolog):Putative translation initiation inhibitor, yjgF family:Citrate synthase:Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component, and related enzymes:2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, and related enzymes:Superoxide dismutase:Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes:Ribonucleases G and E:Tetrahydrodipicolinate N-succinyltransferase:Amino acid transport and metabolism:Coenzyme transport and metabolism:Translation, ribosomal structure and biogenesis:Inorganic ion transport and metabolism:Glycolysis / Gluconeogenesis:Citrate cycle (TCA cycle):Glycine serine and threonine metabolism:Valine leucine and isoleucine degradation:Lysine biosynthesis:Lysine degradation:Tryptophan metabolism:Pyruvate metabolism:Glyoxylate and dicarboxylate metabolism:Porphyrin and chlorophyll metabolism:Aminoacyl-tRNA biosynthesis:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:RNA degradation:TIGR00004:gatB:2oxo_dh_E1:hemL:RNaseEG:sucB:lipoamide_DH:cit_synth_I:DapD_gpp:Biosynthesis of cofactors, prosthetic groups, and carriers:Heme, porphyrin, and cobalamin:Information storage and processing:Metabolism:Transcription:TCA cycle:Energy metabolism:Metabolism:Metabolism:Global:Folding Sorting and Degradation:Translation:Genetic Information Processing:Metabolism of Cofactors and Vitamins:Amino Acid Metabolism:Degradation of RNA:Carbohydrate Metabolism:Protein synthesis:tRNA aminoacylation" 245 "Ammonia permease:Integral membrane protein possibly involved in chromosome condensation:Predicted epimerase, PhzC/PhzF homolog:Spermidine synthase:Predicted dehydrogenase:tRNA nucleotidyltransferase/poly(A) polymerase:High-affinity Fe2+/Pb2+ permease:Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain:FOG: TPR repeat, SEL1 subfamily:ABC-type amino acid transport/signal transduction systems, periplasmic component/domain:Membrane-fusion protein:Predicted nucleoside-diphosphate sugar epimerase:Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs:Uncharacterized membrane protein:Transcriptional regulator:Subtilisin-like serine proteases:Uncharacterized conserved protein:Beta-propeller domains of methanol dehydrogenase type:Serine/threonine protein kinase involved in cell cycle control:Protein implicated in iron transport, frataxin homolog:3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases:AraC-type DNA-binding domain-containing proteins:Predicted enzyme related to lactoylglutathione lyase:Predicted membrane protein:Predicted membrane protein:Uncharacterized conserved protein:Ketosteroid isomerase homolog:Predicted ATPase:Predicted signal transduction protein containing sensor and EAL domains:Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain:Cell cycle control, cell division, chromosome partitioning:Amino acid transport and metabolism:Lipid transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:Cell wall/membrane/envelope biogenesis:Posttranslational modification, protein turnover, chaperones:Inorganic ion transport and metabolism:Valine leucine and isoleucine degradation:Arginine and proline metabolism:Metabolic pathways:Two-component system:General function prediction only:Function unknown:Signal transduction mechanisms:sensory_box:crcB:PhzF_family:amt:RND_mfp:yfcH:TIGR02246:FeS_CyaY:Unknown function:Conserved:Hypothetical proteins:Toxin production and resistance:Cellular processes:Cations and iron carrying compounds:Unknown substrate:Transport and binding proteins:Small molecule interactions:Regulatory functions:Metabolism:Global:Signal Transduction:Environmental Information Processing:Metabolism:Amino Acid Metabolism:Poorly characterized:Metabolism:Cellular processes and signaling:Information storage and processing:Other:Biosynthesis of cofactors, prosthetic groups, and carriers:General" 246 "Energy production and conversion:Short-chain dehydrogenases of various substrate specificities:Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II:Glycerol-3-phosphate dehydrogenase:NADPH:quinone reductase and related Zn-dependent oxidoreductases:Esterase/lipase:Sugar (pentulose and hexulose) kinases:Uncharacterized protein conserved in bacteria:Transcriptional regulator:Acetyltransferases, including N-acetylases of ribosomal proteins:NADH:flavin oxidoreductases, Old Yellow Enzyme family:Long-chain fatty acid transport protein:Predicted flavoprotein involved in K+ transport:Multiple antibiotic transporter:Adenosine deaminase:Arabinose efflux permease:Putative ammonia monooxygenase:Uncharacterized protein conserved in bacteria:Uncharacterized protein conserved in bacteria:Predicted dioxygenase of extradiol dioxygenase family:Streptomycin 6-kinase:TRAP-type uncharacterized transport system, fused permease components:Lipase chaperone:Nucleotide transport and metabolism:Carbohydrate transport and metabolism:Lipid transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:Posttranslational modification, protein turnover, chaperones:Inorganic ion transport and metabolism:Fatty acid metabolism:Glycerophospholipid metabolism:Nitrotoluene degradation:Microbial metabolism in diverse environments:Two-component system:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:Function unknown:TIGR00427:TRAP_fused:Gneg_AbrB_dup:Intracellular trafficking, secretion, and vesicular transport:Defense mechanisms:Lipid Metabolism:Metabolism:Poorly characterized:Metabolism:Cellular processes and signaling:Information storage and processing:General:Unknown function:Unknown substrate:Transport and binding proteins:Metabolism:Global:Signal Transduction:Environmental Information Processing:Xenobiotics Biodegradation and Metabolism" 247 "Aspartate-semialdehyde dehydrogenase:Orotidine-5'-phosphate decarboxylase:Predicted redox protein, regulator of disulfide bond formation:Predicted permease:Predicted permeases:Amino acid permeases:ABC-type amino acid transport/signal transduction systems, periplasmic component/domain:Predicted branched-chain amino acid permease (azaleucine resistance):Uncharacterized protein conserved in bacteria:Uncharacterized protein, possibly involved in aromatic compounds catabolism:Glutaminase:Multiple antibiotic transporter:Fe2+-dicitrate sensor, membrane component:Predicted membrane protein:Predicted membrane protein:Uncharacterized protein conserved in bacteria:Predicted permease, DMT superfamily:Amino acid transport and metabolism:Nucleotide transport and metabolism:Posttranslational modification, protein turnover, chaperones:Inorganic ion transport and metabolism:Pyrimidine metabolism:Alanine aspartate and glutamate metabolism:Glycine serine and threonine metabolism:Cysteine and methionine metabolism:Lysine biosynthesis:Arginine and proline metabolism:D-Glutamine and D-glutamate metabolism:Nitrogen metabolism:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:Function unknown:Signal transduction mechanisms:TIGR00046:unchar_dom_1:pyrF:Gln_ase:Intracellular trafficking, secretion, and vesicular transport:Poorly characterized:Metabolism:Cellular processes and signaling:tRNA and rRNA base modification:Protein synthesis:Pyrimidine ribonucleotide biosynthesis:Purines, pyrimidines, nucleosides, and nucleotides:Amino acids and amines:Energy metabolism:Metabolism:Metabolism:Global:Metabolism of Other Amino Acids:Amino Acid Metabolism:Nucleotide Metabolism:Energy Metabolism" 248 "FOG: CBS domain:Sugar kinases, ribokinase family:ABC-type amino acid transport/signal transduction systems, periplasmic component/domain:ABC-type sugar transport system, ATPase component:Ribose/xylose/arabinose/galactoside ABC-type transport systems, permease components:Amidases related to nicotinamidase:Transcriptional regulators:Acetyltransferases, including N-acetylases of ribosomal proteins:Uncharacterized conserved protein:Serine/threonine protein kinase involved in cell cycle control:ABC-type sugar transport system, periplasmic component:Adenosine deaminase:Uncharacterized protein, similar to the N-terminal domain of Lon protease:Regulator of sigma D:Uncharacterized protein conserved in bacteria:Transcriptional activator of acetoin/glycerol metabolism:Uncharacterized protein conserved in bacteria:Predicted integral membrane protein:Cell cycle control, cell division, chromosome partitioning:Amino acid transport and metabolism:Nucleotide transport and metabolism:Carbohydrate transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:Pentose phosphate pathway:ABC transporters:Bacterial chemotaxis:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:Function unknown:Signal transduction mechanisms:D_ribokin_bact:Environmental Information Processing:Carbohydrate Metabolism:Metabolism:Poorly characterized:Metabolism:Cellular processes and signaling:Information storage and processing:Sugars:Energy metabolism:Cell Motility:Cellular Processes:Membrane Transport" 249 "Energy production and conversion:FAD/FMN-containing dehydrogenases:Phosphoserine phosphatase:Uncharacterized membrane-associated protein:Membrane proteins related to metalloendopeptidases:Membrane carboxypeptidase (penicillin-binding protein):ABC-type transport system involved in cytochrome c biogenesis, permease component:ABC-type transport system involved in cytochrome c biogenesis, permease component:Uncharacterized protein conserved in bacteria:Metal-dependent hydrolase:ABC-type transport system involved in cytochrome c biogenesis, ATPase component:Thiol:disulfide interchange protein:Amino acid transport and metabolism:Cell wall/membrane/envelope biogenesis:Posttranslational modification, protein turnover, chaperones:Glycine serine and threonine metabolism:Peptidoglycan biosynthesis:Methane metabolism:Metabolic pathways:Microbial metabolism in diverse environments:ABC transporters:General function prediction only:Function unknown:ccmA:ccmB:ccmC:PBP_1b:HSK-PSP:Cellular processes and signaling:Biosynthesis and degradation of murein sacculus and peptidoglycan:Cell envelope:Other:Transport and binding proteins:Metabolism:Metabolism:Global:Membrane Transport:Environmental Information Processing:Glycan Biosynthesis and Metabolism:Amino Acid Metabolism:Poorly characterized:Energy Metabolism:Metabolism" 250 "Energy production and conversion:Anthranilate/para-aminobenzoate synthases component I:Sulfite reductase, beta subunit (hemoprotein):Pyridoxamine-phosphate oxidase:Polyferredoxin:Predicted epimerase, PhzC/PhzF homolog:Uncharacterized NAD(FAD)-dependent dehydrogenases:2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases:Glycine/D-amino acid oxidases (deaminating):Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs:Isochorismate hydrolase:3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase:Cbb3-type cytochrome oxidase, subunit 1:Uncharacterized protein conserved in bacteria:Amino acid transport and metabolism:Coenzyme transport and metabolism:Transcription:Posttranslational modification, protein turnover, chaperones:Inorganic ion transport and metabolism:Oxidative phosphorylation:Phenylalanine tyrosine and tryptophan biosynthesis:Cyanoamino acid metabolism:Sulfur metabolism:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:Function unknown:pdxH:PhzF_family:ccoN:ccoG_rdxA_fixG:Cellular processes and signaling:Energy Metabolism:Amino Acid Metabolism:Metabolism of Other Amino Acids:Global:Metabolism:Energy metabolism:Electron transport:Cellular processes:Toxin production and resistance:Biosynthesis of cofactors, prosthetic groups, and carriers:Pyridoxine:Information storage and processing:Metabolism:Metabolism:Poorly characterized" 251 "Phosphoglycerate dehydrogenase and related dehydrogenases:Phosphoribosylanthranilate isomerase:Quinolinate synthase:FKBP-type peptidyl-prolyl cis-trans isomerases 1:Fe2+/Zn2+ uptake regulation proteins:ADP-ribose pyrophosphatase:Cold shock proteins:Arsenate reductase and related proteins, glutaredoxin family:Chorismate mutase:Acyl-CoA hydrolase:Protein-disulfide isomerase:Acetyltransferases, including N-acetylases of ribosomal proteins:Uncharacterized protein conserved in bacteria:Transcriptional regulators:Oligoketide cyclase/lipid transport protein:Small protein A (tmRNA-binding):Uncharacterized protein conserved in bacteria:Predicted metal-binding protein related to the C-terminal domain of SecA:Amino acid transport and metabolism:Nucleotide transport and metabolism:Coenzyme transport and metabolism:Lipid transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:Posttranslational modification, protein turnover, chaperones:Inorganic ion transport and metabolism:Purine metabolism:Phenylalanine tyrosine and tryptophan biosynthesis:Nicotinate and nicotinamide metabolism:Biosynthesis of unsaturated fatty acids:Metabolic pathways:Biosynthesis of secondary metabolites:General function prediction only:Function unknown:nadA:thioredoxin:arsC_related:CM_mono2:ygfB_yecA:Metabolism:Lipid Metabolism:Nucleotide Metabolism:Amino Acid Metabolism:Metabolism of Cofactors and Vitamins:Global:Metabolism:Energy metabolism:Electron transport:Regulatory functions:DNA interactions:Unknown function:General:Amino acid biosynthesis:Aromatic amino acid family:Biosynthesis of cofactors, prosthetic groups, and carriers:Pyridine nucleotides:Information storage and processing:Cellular processes and signaling:Metabolism:Poorly characterized" 252 "Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II:Transcriptional regulator:Uncharacterized proteins of the AP superfamily:ABC-type Fe3+ transport system, periplasmic component:3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases:ATP-dependent transcriptional regulator:Uncharacterized protein conserved in bacteria:Lipid transport and metabolism:Transcription:Inorganic ion transport and metabolism:Valine leucine and isoleucine degradation:Metabolic pathways:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:Function unknown:HIBADH:Global:Information storage and processing:Amino Acid Metabolism:Metabolism:Poorly characterized:Metabolism:Amino acids and amines:Energy metabolism:Metabolism" 253 "Energy production and conversion:Predicted Co/Zn/Cd cation transporters:Acetyltransferase (isoleucine patch superfamily):Dethiobiotin synthetase:7-keto-8-aminopelargonate synthetase and related enzymes:Short-chain dehydrogenases of various substrate specificities:Nucleoside-diphosphate-sugar epimerases:Transcriptional regulator:Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily):Signal transduction histidine kinase:Predicted oxidoreductases (related to aryl-alcohol dehydrogenases):Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain:Predicted hydrolase (HAD superfamily):Secreted/periplasmic Zn-dependent peptidases, insulinase-like:Predicted membrane protein:Uncharacterized proteins, homologs of microcin C7 resistance protein MccF:Beta-lactamase class C and other penicillin binding proteins:Uncharacterized conserved protein (some members contain a von Willebrand factor type A (vWA) domain):Predicted transcriptional regulators:Predicted esterase of the alpha-beta hydrolase superfamily:Uncharacterized conserved protein:Uncharacterized protein, possibly involved in aromatic compounds catabolism:Transcriptional regulators:AraC-type DNA-binding domain-containing proteins:Lysophospholipase L1 and related esterases:Small-conductance mechanosensitive channel:Sugar diacid utilization regulator:Predicted enolase-phosphatase:Signal transduction histidine kinase involved in nitrogen fixation and metabolism regulation:Amino acid transport and metabolism:Carbohydrate transport and metabolism:Coenzyme transport and metabolism:Transcription:Cell wall/membrane/envelope biogenesis:Posttranslational modification, protein turnover, chaperones:Inorganic ion transport and metabolism:Purine metabolism:Pyrimidine metabolism:Cysteine and methionine metabolism:Biotin metabolism:Metabolic pathways:Two-component system:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:Function unknown:Signal transduction mechanisms:sensory_box:bioD:unchar_dom_1:mazG:yihY_not_rbn:bioF:CDF:HAD-SF-IA-v3:enolase-ppase:PQQ_syn_pqqF:Defense mechanisms:Small molecule interactions:Regulatory functions:Sulfur metabolism:Central intermediary metabolism:Metabolism:Global:Signal Transduction:Environmental Information Processing:Metabolism of Cofactors and Vitamins:Amino Acid Metabolism:Nucleotide Metabolism:Poorly characterized:Metabolism:Cellular processes and signaling:Information storage and processing:Biotin:Metabolism:Other:Biosynthesis of cofactors, prosthetic groups, and carriers:General:Enzymes of unknown specificity:Unknown function:Cations and iron carrying compounds:Transport and binding proteins" 254 "Energy production and conversion:Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase]:Glycosyltransferase:Adenylylsulfate kinase and related kinases:ABC-type nitrate/sulfonate/bicarbonate transport system, permease component:Mannose-6-phosphate isomerase:NAD-dependent aldehyde dehydrogenases:Flavodoxin reductases (ferredoxin-NADPH reductases) family 1:Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases):UDP-glucose 4-epimerase:Predicted glycosyltransferases:Transcriptional regulator:Purine-cytosine permease and related proteins:Lysophospholipase:Mn-containing catalase:Uncharacterized protein conserved in bacteria:ABC-type uncharacterized transport system, ATPase component:Phenylpropionate dioxygenase and related ring-hydroxylating dioxygenases, large terminal subunit:Site-specific recombinase XerC:Amino acid transport and metabolism:Nucleotide transport and metabolism:Carbohydrate transport and metabolism:Coenzyme transport and metabolism:Lipid transport and metabolism:Transcription:Replication, recombination and repair:Cell wall/membrane/envelope biogenesis:Inorganic ion transport and metabolism:Galactose metabolism:Purine metabolism:Glycine serine and threonine metabolism:Selenocompound metabolism:Amino sugar and nucleotide sugar metabolism:Sulfur metabolism:Metabolic pathways:Microbial metabolism in diverse environments:ABC transporters:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:Function unknown:apsK:galE:Energy Metabolism:Cellular processes and signaling:Carbohydrate Metabolism:Metabolism:Poorly characterized:Information storage and processing:Metabolism:Sugars:Energy metabolism:Sulfur metabolism:Central intermediary metabolism:Metabolism:Global:Membrane Transport:Environmental Information Processing:Metabolism of Other Amino Acids:Amino Acid Metabolism:Nucleotide Metabolism" 255 "Translation initiation factor 1 (eIF-1/SUI1) and related proteins:1-acyl-sn-glycerol-3-phosphate acyltransferase:Zn-dependent protease with chaperone function:Transcriptional regulator:tmRNA-binding protein:Alanine racemase:ABC-type amino acid transport/signal transduction systems, periplasmic component/domain:Membrane-fusion protein:Predicted Rossmann fold nucleotide-binding protein:Predicted redox protein, regulator of disulfide bond formation:Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain:Uncharacterized protein conserved in bacteria:Uncharacterized protein conserved in bacteria:Uncharacterized protein conserved in bacteria:Aspartyl/asparaginyl beta-hydroxylase and related dioxygenases:Amino acid transport and metabolism:Lipid transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:Cell wall/membrane/envelope biogenesis:Posttranslational modification, protein turnover, chaperones:D-Alanine metabolism:Metabolic pathways:Two-component system:General function prediction only:Function unknown:Signal transduction mechanisms:smpB:alr:TIGR00730:SUI1_rel:RND_mfp:MJ0042_CXXC:DnaA_homol_Hda:organ_hyd_perox:Biosynthesis and degradation of murein sacculus and peptidoglycan:Metabolism of Other Amino Acids:Environmental Information Processing:Signal Transduction:Global:Metabolism:DNA metabolism:DNA replication, recombination, and repair:Protein synthesis:Other:Translation factors:Transport and binding proteins:Unknown substrate:Cellular processes:Detoxification:Hypothetical proteins:Conserved:Cell envelope:Metabolism:Information storage and processing:Cellular processes and signaling:Metabolism:Poorly characterized" 256 "Folylpolyglutamate synthase:3-oxoacyl-(acyl-carrier-protein) synthase:(acyl-carrier-protein) S-malonyltransferase:3-oxoacyl-[acyl-carrier-protein] synthase III:Biotin carboxylase:Biotin carboxyl carrier protein:3-dehydroquinate dehydratase II:3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratases:Acetyl-CoA carboxylase beta subunit:Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases):Acyl-[acyl carrier protein]--UDP-N-acetylglucosamine O-acyltransferase:Aspartate/tyrosine/aromatic aminotransferase:Uncharacterized paraquat-inducible protein B:Uncharacterized protein conserved in bacteria:Amino acid transport and metabolism:Coenzyme transport and metabolism:Lipid transport and metabolism:Cell wall/membrane/envelope biogenesis:Fatty acid biosynthesis:Cysteine and methionine metabolism:Tyrosine metabolism:Phenylalanine metabolism:Phenylalanine tyrosine and tryptophan biosynthesis:Novobiocin biosynthesis:Lipopolysaccharide biosynthesis:Pyruvate metabolism:Propanoate metabolism:Carbon fixation pathways in prokaryotes:Folate biosynthesis:Aminoacyl-tRNA biosynthesis:Biosynthesis of unsaturated fatty acids:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:Function unknown:fabD:accC:accD:BCCP:aroQ:folC:fabA:fabZ:3oxo_ACP_reduc:lipid_A_lpxA:Metabolism:Poorly characterized:Cell envelope:Folic acid:Biosynthesis of cofactors, prosthetic groups, and carriers:Aromatic amino acid family:Amino acid biosynthesis:Biosynthesis:Fatty acid and phospholipid metabolism:Metabolism:Metabolism:Global:Translation:Genetic Information Processing:Biosynthesis of Other Secondary Metabolites:Metabolism of Cofactors and Vitamins:Glycan Biosynthesis and Metabolism:Amino Acid Metabolism:Lipid Metabolism:Energy Metabolism:Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides:Carbohydrate Metabolism:Cellular processes and signaling" 257 "Energy production and conversion:Transcriptional regulator:ABC-type nitrate/sulfonate/bicarbonate transport system, permease component:NADPH:quinone reductase and related Zn-dependent oxidoreductases:ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components:Cell division protein FtsI/penicillin-binding protein 2:ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component:Putative threonine efflux protein:Transcriptional regulator:Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL homologs:DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog:Acyl-CoA dehydrogenases:Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS/CutS homologs:Uncharacterized conserved protein:Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases:AraC-type DNA-binding domain-containing proteins:Uncharacterized conserved protein:Prophage antirepressor:Fe2+-dicitrate sensor, membrane component:Amino acid transport and metabolism:Lipid transport and metabolism:Transcription:Cell wall/membrane/envelope biogenesis:Inorganic ion transport and metabolism:Peptidoglycan biosynthesis:ABC transporters:RNA polymerase:General function prediction only:Function unknown:Signal transduction mechanisms:ahpD_dom:TAT_signal_seq:sigma70-ECF:oxido_grp_1:Information storage and processing:General:Enzymes of unknown specificity:Unknown function:Protein and peptide secretion and trafficking:Protein fate:Membrane Transport:Environmental Information Processing:Transcription:Genetic Information Processing:Glycan Biosynthesis and Metabolism:Metabolism:Poorly characterized:Metabolism:Cellular processes and signaling" 258 "Energy production and conversion:Putative translation initiation inhibitor, yjgF family:Transcriptional regulator:ABC-type amino acid transport/signal transduction systems, periplasmic component/domain:NAD-dependent aldehyde dehydrogenases:Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases):Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs:Amidases related to nicotinamidase:Pirin-related protein:Predicted redox protein, regulator of disulfide bond formation:Uncharacterized conserved protein, contains double-stranded beta-helix domain:Acyl-CoA dehydrogenases:Uncharacterized protein involved in propionate catabolism:Uncharacterized conserved protein:Serine phosphatase RsbU, regulator of sigma subunit:Cyclopropane fatty acid synthase and related methyltransferases:Urocanate hydratase:Amino acid transport and metabolism:Lipid transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:Cell wall/membrane/envelope biogenesis:Posttranslational modification, protein turnover, chaperones:Glycolysis / Gluconeogenesis:Pentose and glucuronate interconversions:Ascorbate and aldarate metabolism:Fatty acid metabolism:Valine leucine and isoleucine degradation:Lysine degradation:Arginine and proline metabolism:Histidine metabolism:Tryptophan metabolism:beta-Alanine metabolism:Glycerolipid metabolism:Pyruvate metabolism:Chloroalkane and chloroalkene degradation:Propanoate metabolism:Limonene and pinene degradation:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:ABC transporters:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:Function unknown:Signal transduction mechanisms:ahpD_dom:hutU:prpD:Amino acids and amines:Carbohydrate Metabolism:Lipid Metabolism:Amino Acid Metabolism:Metabolism of Other Amino Acids:Metabolism of Terpenoids and Polyketides:Xenobiotics Biodegradation and Metabolism:Environmental Information Processing:Membrane Transport:Global:Metabolism:Energy metabolism:Metabolism:Unknown function:General:Information storage and processing:Cellular processes and signaling:Metabolism:Poorly characterized" 259 "Energy production and conversion:DNA-directed RNA polymerase, beta subunit/140 kD subunit:DNA-directed RNA polymerase, beta' subunit/160 kD subunit:Ribosome recycling factor:Topoisomerase IA:Acyl-[acyl carrier protein]--UDP-N-acetylglucosamine O-acyltransferase:UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase:GTPase:Polyribonucleotide nucleotidyltransferase (polynucleotide phosphorylase):Cytochrome c, mono- and diheme variants:Outer membrane protein:Cbb3-type cytochrome oxidase, cytochrome c subunit:Cbb3-type cytochrome oxidase, subunit 1:Outer membrane protein/protective antigen OMA87:Translation, ribosomal structure and biogenesis:Transcription:Replication, recombination and repair:Cell wall/membrane/envelope biogenesis:Posttranslational modification, protein turnover, chaperones:Oxidative phosphorylation:Purine metabolism:Pyrimidine metabolism:Lipopolysaccharide biosynthesis:Metabolic pathways:RNA degradation:RNA polymerase:General function prediction only:small_GTP:frr:ccoN:ccoO:ccoP:topA_bact:lipid_A_lpxA:lipid_A_lpxD:rpoB:rpoC_TIGR:OM_YaeT:polynuc_phos:Cell envelope:Energy Metabolism:Nucleotide Metabolism:Glycan Biosynthesis and Metabolism:Genetic Information Processing:Transcription:Folding Sorting and Degradation:Global:Metabolism:Energy metabolism:Electron transport:DNA metabolism:DNA replication, recombination, and repair:Transcription:Degradation of RNA:DNA-dependent RNA polymerase:Protein synthesis:Translation factors:Protein fate:Protein and peptide secretion and trafficking:Unknown function:General:Metabolism:Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides:Information storage and processing:Cellular processes and signaling:Metabolism:Poorly characterized" 260 "Alanyl-tRNA synthetase:Phenylalanyl-tRNA synthetase alpha subunit:Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase:Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase:Phosphoribosylformimino-5-aminoimidazole carboxamide ribonucleotide (ProFAR) isomerase:3-phosphoglycerate kinase:Argininosuccinate synthase:Enolase:Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), B subunit:Cytosine deaminase and related metal-dependent hydrolases:Homoserine dehydrogenase:Tetrahydrodipicolinate N-succinyltransferase:Amino acid transport and metabolism:Nucleotide transport and metabolism:Carbohydrate transport and metabolism:Translation, ribosomal structure and biogenesis:Replication, recombination and repair:Glycolysis / Gluconeogenesis:Pyrimidine metabolism:Alanine aspartate and glutamate metabolism:Glycine serine and threonine metabolism:Cysteine and methionine metabolism:Lysine biosynthesis:Arginine and proline metabolism:Histidine metabolism:Tyrosine metabolism:Phenylalanine metabolism:Phenylalanine tyrosine and tryptophan biosynthesis:Novobiocin biosynthesis:Methane metabolism:Vitamin B6 metabolism:Aminoacyl-tRNA biosynthesis:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:RNA degradation:General function prediction only:TIGR00007:argG:alaS:pheS:parE_Gneg:eno:hisC:E4PD_g-proteo:DapD_gpp:Metabolism:Global:Folding Sorting and Degradation:Translation:Genetic Information Processing:Biosynthesis of Other Secondary Metabolites:Metabolism:Metabolism of Cofactors and Vitamins:Amino Acid Metabolism:Nucleotide Metabolism:Energy Metabolism:Carbohydrate Metabolism:Energy metabolism:Glycolysis/gluconeogenesis:DNA metabolism:DNA replication, recombination, and repair:Protein synthesis:tRNA aminoacylation:Amino acid biosynthesis:Glutamate family:Histidine family:Biosynthesis of cofactors, prosthetic groups, and carriers:Pyridoxine:Information storage and processing:Metabolism:Poorly characterized" 261 "Phosphoribosyl-AMP cyclohydrolase:Porphobilinogen deaminase:1-acyl-sn-glycerol-3-phosphate acyltransferase:Superfamily I DNA and RNA helicases:Predicted redox protein, regulator of disulfide bond formation:Predicted phosphatases:Phosphatidylglycerophosphate synthase:Pseudouridylate synthases, 23S RNA-specific:Periplasmic serine proteases (ClpP class):6-pyruvoyl-tetrahydropterin synthase:Putative effector of murein hydrolase:Putative effector of murein hydrolase LrgA:Predicted permeases:Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain:Amino acid transport and metabolism:Coenzyme transport and metabolism:Lipid transport and metabolism:Translation, ribosomal structure and biogenesis:Replication, recombination and repair:Cell wall/membrane/envelope biogenesis:Posttranslational modification, protein turnover, chaperones:Histidine metabolism:Glycerophospholipid metabolism:Glyoxylate and dicarboxylate metabolism:Folate biosynthesis:Porphyrin and chlorophyll metabolism:Metabolic pathways:Biosynthesis of secondary metabolites:Nucleotide excision repair:Mismatch repair:Sulfur relay system:General function prediction only:Signal transduction mechanisms:rluA_subfam:hemC:GGDEF:pgsA:rarD:SppA_dom:uvrD:HAD-SF-IA-v3:queuosine_QueD:Intracellular trafficking, secretion, and vesicular transport:Other:Information storage and processing:Cellular processes and signaling:Metabolism:Poorly characterized:Metabolism:Metabolism:Global:Replication and Repair:Folding Sorting and Degradation:Genetic Information Processing:Metabolism of Cofactors and Vitamins:Amino Acid Metabolism:Lipid Metabolism:Carbohydrate Metabolism:Fatty acid and phospholipid metabolism:Biosynthesis:DNA metabolism:DNA replication, recombination, and repair:Protein synthesis:tRNA and rRNA base modification:Protein fate:Degradation of proteins, peptides, and glycopeptides:Transport and binding proteins:Unknown substrate:Unknown function:Enzymes of unknown specificity:Biosynthesis of cofactors, prosthetic groups, and carriers:Heme, porphyrin, and cobalamin:Signal transduction" 262 "Guanosine polyphosphate pyrophosphohydrolases/synthetases:Lipoate-protein ligase B:Preprotein translocase subunit SecA (ATPase, RNA helicase):3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratases:UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase:ABC-type (unclassified) transport system, ATPase component:Low specificity phosphatase (HAD superfamily):Uncharacterized protein conserved in bacteria:Protein-L-isoaspartate carboxylmethyltransferase:Uncharacterized protein conserved in bacteria:Outer membrane protein/protective antigen OMA87:Coenzyme transport and metabolism:Lipid transport and metabolism:Transcription:Cell wall/membrane/envelope biogenesis:Posttranslational modification, protein turnover, chaperones:Fatty acid biosynthesis:Purine metabolism:Lipopolysaccharide biosynthesis:Lipoic acid metabolism:Metabolic pathways:ABC transporters:Protein export:Bacterial secretion system:General function prediction only:Function unknown:Signal transduction mechanisms:pimt:lipB:spoT_relA:secA:YrbI-phosphatas:fabZ:lipid_A_lpxD:outer_YhbN_LptA:OM_YaeT:Intracellular trafficking, secretion, and vesicular transport:Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides:Lipid Metabolism:Nucleotide Metabolism:Glycan Biosynthesis and Metabolism:Metabolism of Cofactors and Vitamins:Genetic Information Processing:Folding Sorting and Degradation:Environmental Information Processing:Membrane Transport:Global:Metabolism:Fatty acid and phospholipid metabolism:Biosynthesis:Protein fate:Protein and peptide secretion and trafficking:Protein modification and repair:Transport and binding proteins:Other:Cellular processes:Adaptations to atypical conditions:Cell envelope:Metabolism:Information storage and processing:Cellular processes and signaling:Metabolism:Poorly characterized" 263 "Argininosuccinate lyase:Glycosyltransferases involved in cell wall biogenesis:ABC-type molybdate transport system, periplasmic component:Membrane proteins related to metalloendopeptidases:DNA polymerase I - 3'-5' exonuclease and polymerase domains:Predicted endonuclease distantly related to archaeal Holliday junction resolvase:Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases):Transcriptional regulators:Putative transcriptional regulator:Lysophospholipase:Predicted molecular chaperone distantly related to HSP70-fold metalloproteases:Predicted carboxypeptidase:Peptidylarginine deiminase and related enzymes:Nucleoid-associated protein:Putative lipoprotein:ABC-type molybdate transport system, ATPase component:ABC-type molybdate transport system, permease component:Amino acid transport and metabolism:Lipid transport and metabolism:Transcription:Replication, recombination and repair:Cell wall/membrane/envelope biogenesis:Posttranslational modification, protein turnover, chaperones:Inorganic ion transport and metabolism:Purine metabolism:Pyrimidine metabolism:Alanine aspartate and glutamate metabolism:Arginine and proline metabolism:One carbon pool by folate:Folate biosynthesis:Metabolic pathways:Biosynthesis of secondary metabolites:ABC transporters:DNA replication:Base excision repair:Nucleotide excision repair:Homologous recombination:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:TIGR00252:pola:argH:modA:modB_ABC:modC_ABC:fruct_sucro_rep:agmatine_aguA:Polyamine biosynthesis:Central intermediary metabolism:Metabolism:Global:Metabolism:Membrane Transport:Environmental Information Processing:Replication and Repair:Genetic Information Processing:Metabolism of Cofactors and Vitamins:Amino Acid Metabolism:Regulatory functions:Nucleotide Metabolism:DNA interactions:DNA metabolism:DNA replication, recombination, and repair:Transport and binding proteins:Anions:Hypothetical proteins:Conserved:Amino acid biosynthesis:Glutamate family:Information storage and processing:Cellular processes and signaling:Metabolism:Poorly characterized" 264 "Energy production and conversion:Leucyl aminopeptidase:Citrate synthase:Predicted oxidoreductases (related to aryl-alcohol dehydrogenases):Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases):Aconitase A:Transcriptional regulators:Electron transfer flavoprotein, alpha subunit:Uncharacterized protein, possibly involved in aromatic compounds catabolism:Isocitrate lyase:Malate synthase:PEP phosphonomutase and related enzymes:Uncharacterized protein conserved in bacteria:Predicted aminoglycoside phosphotransferase:Signal transduction protein containing GAF and PtsI domains:Amino acid transport and metabolism:Carbohydrate transport and metabolism:Lipid transport and metabolism:Transcription:Citrate cycle (TCA cycle):Glutathione metabolism:Pyruvate metabolism:Glyoxylate and dicarboxylate metabolism:Propanoate metabolism:Carbon fixation pathways in prokaryotes:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:Phosphotransferase system (PTS):Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:Function unknown:Signal transduction mechanisms:malate_syn_G:PTS_I_fam:cit_synth_II:prpB:2met_isocit_dHY:prpF:Cellular processes and signaling:Information storage and processing:TCA cycle:Fermentation:Energy metabolism:Metabolism:Metabolism:Global:Membrane Transport:Environmental Information Processing:Metabolism of Other Amino Acids:Energy Metabolism:Poorly characterized:Carbohydrate Metabolism:Metabolism" 265 "Zn-dependent protease with chaperone function:Uncharacterized protein involved in formation of curli polymers:Hemolysin activation/secretion protein:Predicted membrane protein:Uncharacterized protein conserved in bacteria:Uncharacterized protein conserved in bacteria:Uncharacterized protein conserved in bacteria:Cell wall/membrane/envelope biogenesis:Posttranslational modification, protein turnover, chaperones:Aminoacyl-tRNA biosynthesis:Function unknown:VI_chp_8:Intracellular trafficking, secretion, and vesicular transport:Translation:Genetic Information Processing:Poorly characterized:Cellular processes and signaling" 266 "Energy production and conversion:Gamma-glutamyltransferase:Glycerol-3-phosphate dehydrogenase:Transcriptional regulator:Glutathione S-transferase:Aldo/keto reductases, related to diketogulonate reductase:Predicted oxidoreductases (related to aryl-alcohol dehydrogenases):Predicted permeases:Enoyl-CoA hydratase/carnithine racemase:Beta-propeller domains of methanol dehydrogenase type:3-deoxy-D-manno-octulosonic-acid transferase:Predicted membrane protein/domain:Membrane transporters of cations and cationic drugs:Uncharacterized vancomycin resistance protein:Arabinose efflux permease:Predicted signal transduction protein containing sensor and EAL domains:Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain:Predicted permease, DMT superfamily:Amino acid transport and metabolism:Carbohydrate transport and metabolism:Lipid transport and metabolism:Transcription:Cell wall/membrane/envelope biogenesis:Posttranslational modification, protein turnover, chaperones:Inorganic ion transport and metabolism:Fatty acid metabolism:Valine leucine and isoleucine degradation:Geraniol degradation:Lysine degradation:Benzoate degradation:Tryptophan metabolism:beta-Alanine metabolism:Taurine and hypotaurine metabolism:Selenocompound metabolism:Cyanoamino acid metabolism:Glutathione metabolism:Lipopolysaccharide biosynthesis:Arachidonic acid metabolism:Aminobenzoate degradation:Propanoate metabolism:Butanoate metabolism:Limonene and pinene degradation:Caprolactam degradation:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:General function prediction only:Function unknown:Signal transduction mechanisms:sensory_box:phn_lysR:Defense mechanisms:Carbohydrate Metabolism:Metabolism:Poorly characterized:Information storage and processing:Small molecule interactions:Regulatory functions:Metabolism:Global:Xenobiotics Biodegradation and Metabolism:Metabolism of Terpenoids and Polyketides:Glycan Biosynthesis and Metabolism:Metabolism:Metabolism of Other Amino Acids:Amino Acid Metabolism:Lipid Metabolism:Cellular processes and signaling" 267 "Energy production and conversion:Putative translation initiation inhibitor, yjgF family:Dihydrodipicolinate synthase/N-acetylneuraminate lyase:Ketopantoate hydroxymethyltransferase:Amino acid transporters:Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases:Signal transduction histidine kinase:Membrane-associated phospholipid phosphatase:Spermidine/putrescine-binding periplasmic protein:NAD-dependent aldehyde dehydrogenases:Predicted acetyltransferases and hydrolases with the alpha/beta hydrolase fold:ABC-type spermidine/putrescine transport system, permease component I:ABC-type spermidine/putrescine transport system, permease component II:ABC-type transport system involved in multi-copper enzyme maturation, permease component:Predicted flavoprotein involved in K+ transport:K+-transporting ATPase, c chain:High-affinity K+ transport system, ATPase chain B:Sugar phosphate permease:Uncharacterized conserved protein:ABC-type spermidine/putrescine transport systems, ATPase components:ABC-type branched-chain amino acid transport system, permease component:Amino acid transport and metabolism:Carbohydrate transport and metabolism:Coenzyme transport and metabolism:Lipid transport and metabolism:Translation, ribosomal structure and biogenesis:Cell wall/membrane/envelope biogenesis:Inorganic ion transport and metabolism:Lysine biosynthesis:Arginine and proline metabolism:Pantothenate and CoA biosynthesis:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:ABC transporters:Two-component system:General function prediction only:Function unknown:Signal transduction mechanisms:panB:sensory_box:kdpC:potA:ATPase_P-type:AcOrn-deacetyl:potass_kdpF:urea_trans_UrtC:Amino acid biosynthesis:Cations and iron carrying compounds:Amino acids, peptides and amines:Transport and binding proteins:Small molecule interactions:Regulatory functions:Metabolism:Metabolism:Global:Signal Transduction:Membrane Transport:Environmental Information Processing:Metabolism of Cofactors and Vitamins:Poorly characterized:Amino Acid Metabolism:Metabolism:Cellular processes and signaling:Information storage and processing:Pantothenate and coenzyme A:Biosynthesis of cofactors, prosthetic groups, and carriers:Glutamate family" 268 "Energy production and conversion:Tyrosyl-tRNA synthetase:Glutathione synthase/Ribosomal protein S6 modification enzyme (glutaminyl transferase):Acetylglutamate kinase:Transcriptional regulator:Na+/proline symporter:Periplasmic serine proteases (ClpP class):Glutathione S-transferase:ABC-type amino acid transport system, permease component:Transcription elongation factor:Methyl-accepting chemotaxis protein:NAD-dependent aldehyde dehydrogenases:Threonine dehydratase:Predicted membrane protein:Predicted membrane protein:Amidases related to nicotinamidase:Transcriptional regulator:Uncharacterized conserved protein:Transcriptional regulators:Outer membrane receptor proteins, mostly Fe transport:Predicted transcriptional regulators:Transcriptional regulators:FOG: PAS/PAC domain:AraC-type DNA-binding domain-containing proteins:Precorrin-6B methylase 1:Transcriptional regulator:Hemolysin activation/secretion protein:Membrane-bound lytic murein transglycosylase B:Predicted permeases:Uncharacterized protein conserved in bacteria:Predicted periplasmic protein:Uncharacterized conserved protein:Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain:Amino acid transport and metabolism:Coenzyme transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:Cell wall/membrane/envelope biogenesis:Cell motility:Posttranslational modification, protein turnover, chaperones:Inorganic ion transport and metabolism:Glycine serine and threonine metabolism:Valine leucine and isoleucine biosynthesis:Arginine and proline metabolism:Phenylalanine metabolism:Styrene degradation:Porphyrin and chlorophyll metabolism:Aminoacyl-tRNA biosynthesis:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:Two-component system:Bacterial chemotaxis:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:Function unknown:Signal transduction mechanisms:sensory_box:tyrS:TIGR00726:OPT_sfam:rimK_fam:ilvA_2Cterm:greB:YCCS:HEQRo_perm_3TM:N-Ac-Glu-synth:MltB_2:HpaR:CbiE:Intracellular trafficking, secretion, and vesicular transport:Transport and binding proteins:tRNA aminoacylation:Protein synthesis:Transcription factors:Transcription:Small molecule interactions:Regulatory functions:Metabolism:Metabolism:Global:Cell Motility:Cellular Processes:Signal Transduction:Environmental Information Processing:Translation:Genetic Information Processing:Xenobiotics Biodegradation and Metabolism:Metabolism of Cofactors and Vitamins:Poorly characterized:Amino Acid Metabolism:Metabolism:Cellular processes and signaling:Information storage and processing:Biosynthesis and degradation of murein sacculus and peptidoglycan:Other:Cell envelope:Pyruvate family:Glutamate family:Amino acid biosynthesis:General:Unknown function:Amino acids, peptides and amines" 269 "Energy production and conversion:Guanylate kinase:Predicted S-adenosylmethionine-dependent methyltransferase:Queuine/archaeosine tRNA-ribosyltransferase:2-methylthioadenine synthetase:Hypoxanthine-guanine phosphoribosyltransferase:Spermidine/putrescine-binding periplasmic protein:Na+/alanine symporter:ABC-type spermidine/putrescine transport system, permease component I:ABC-type spermidine/putrescine transport system, permease component II:Predicted membrane GTPase involved in stress response:Na+/H+-dicarboxylate symporters:Permeases:SAM-dependent methyltransferases related to tRNA (uracil-5-)-methyltransferase:Nucleoside-binding outer membrane protein:Amino acid transport and metabolism:Nucleotide transport and metabolism:Translation, ribosomal structure and biogenesis:Cell wall/membrane/envelope biogenesis:Purine metabolism:Arginine and proline metabolism:beta-Alanine metabolism:Metabolic pathways:Biosynthesis of secondary metabolites:ABC transporters:General function prediction only:Signal transduction mechanisms:TIGR00089:TIGR00091:small_GTP:Q_tRNA_tgt:agcS:trmA_only:guanyl_kin:Metabolism:Global:Membrane Transport:Environmental Information Processing:Metabolism of Other Amino Acids:Amino Acid Metabolism:Protein synthesis:Nucleotide Metabolism:tRNA and rRNA base modification:Unknown function:General:Information storage and processing:Cellular processes and signaling:Metabolism:Poorly characterized:Nucleotide and nucleoside interconversions:Purines, pyrimidines, nucleosides, and nucleotides:Metabolism" 270 "Undecaprenyl pyrophosphate synthase:ATP phosphoribosyltransferase:Preprotein translocase subunit SecF:Predicted redox protein, regulator of disulfide bond formation:Glucosamine 6-phosphate synthetase, contains amidotransferase and phosphosugar isomerase domains:DNA polymerase III, alpha subunit:tRNA nucleotidyltransferase/poly(A) polymerase:1-deoxy-D-xylulose 5-phosphate reductoisomerase:Lipid A disaccharide synthetase:Predicted GTPases:N-acetylglucosamine-1-phosphate uridyltransferase (contains nucleotidyltransferase and I-patch acetyltransferase domains):Putative threonine efflux protein:Uncharacterized protein conserved in bacteria:FOG: WD40-like repeat:Uncharacterized proteins, LmbE homologs:Uncharacterized conserved protein:Cell division protein:Cell cycle control, cell division, chromosome partitioning:Amino acid transport and metabolism:Lipid transport and metabolism:Translation, ribosomal structure and biogenesis:Replication, recombination and repair:Cell wall/membrane/envelope biogenesis:Posttranslational modification, protein turnover, chaperones:Purine metabolism:Pyrimidine metabolism:Alanine aspartate and glutamate metabolism:Histidine metabolism:Amino sugar and nucleotide sugar metabolism:Lipopolysaccharide biosynthesis:Terpenoid backbone biosynthesis:Metabolic pathways:Biosynthesis of secondary metabolites:RNA degradation:DNA replication:Protein export:Bacterial secretion system:Mismatch repair:Homologous recombination:General function prediction only:Function unknown:uppS:hisG:lpxB:Dxr:polc:2A0604s01:2A76:glmS:glmU:pcnB:assembly_YfgL:GTPase_EngA:Intracellular trafficking, secretion, and vesicular transport:Cell envelope:Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides:Information storage and processing:Cellular processes and signaling:Metabolism:Poorly characterized:Metabolism:Global:Membrane Transport:Environmental Information Processing:Metabolism:Replication and Repair:Folding Sorting and Degradation:Genetic Information Processing:Metabolism of Terpenoids and Polyketides:Glycan Biosynthesis and Metabolism:Amino Acid Metabolism:Nucleotide Metabolism:Carbohydrate Metabolism:Central intermediary metabolism:Amino sugars:DNA metabolism:DNA replication, recombination, and repair:Protein synthesis:Other:Protein fate:Protein and peptide secretion and trafficking:Transport and binding proteins:Amino acids, peptides and amines:Amino acid biosynthesis:Histidine family:Biosynthesis of cofactors, prosthetic groups, and carriers:Other" 271 "Pentose-5-phosphate-3-epimerase:Tryptophanyl-tRNA synthetase:1-acyl-sn-glycerol-3-phosphate acyltransferase:Coproporphyrinogen III oxidase:Single-stranded DNA-binding protein:Deoxycytidine deaminase:Asp-tRNAAsn/Glu-tRNAGln amidotransferase C subunit:Protease subunit of ATP-dependent Clp proteases:Formyltetrahydrofolate hydrolase:Uncharacterized homolog of plant Iojap protein:Septum formation inhibitor:Septum formation topological specificity factor:Preprotein translocase subunit YajC:DNA uptake lipoprotein:Conserved secreted protein:Cell cycle control, cell division, chromosome partitioning:Nucleotide transport and metabolism:Carbohydrate transport and metabolism:Coenzyme transport and metabolism:Lipid transport and metabolism:Translation, ribosomal structure and biogenesis:Replication, recombination and repair:Posttranslational modification, protein turnover, chaperones:Pentose phosphate pathway:Pentose and glucuronate interconversions:Pyrimidine metabolism:Tryptophan metabolism:Glycerolipid metabolism:Glycerophospholipid metabolism:Glyoxylate and dicarboxylate metabolism:One carbon pool by folate:Porphyrin and chlorophyll metabolism:Aminoacyl-tRNA biosynthesis:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:DNA replication:Protein export:Bacterial secretion system:Mismatch repair:Homologous recombination:General function prediction only:Function unknown:iojap_ybeB:gatC:trpS:clpP:ssb:PurU:yajC:rpe:minE:minC:dCTP_deam:OM_YfiO:Intracellular trafficking, secretion, and vesicular transport:General:Information storage and processing:Cellular processes and signaling:Metabolism:Poorly characterized:Metabolism:Global:Membrane Transport:Environmental Information Processing:Metabolism:Replication and Repair:Folding Sorting and Degradation:Translation:Genetic Information Processing:Metabolism of Cofactors and Vitamins:Amino Acid Metabolism:Nucleotide Metabolism:Lipid Metabolism:Carbohydrate Metabolism:Energy metabolism:Pentose phosphate pathway:Purines, pyrimidines, nucleosides, and nucleotides:Purine ribonucleotide biosynthesis:2'-Deoxyribonucleotide metabolism:DNA metabolism:DNA replication, recombination, and repair:Protein synthesis:tRNA aminoacylation:Protein fate:Protein and peptide secretion and trafficking:Degradation of proteins, peptides, and glycopeptides:Cellular processes:Cell division:Unknown function" 272 "Energy production and conversion:Predicted GTPase, probable translation factor:Phosphoribosylaminoimidazole (AIR) synthetase:Peptidyl-tRNA hydrolase:Folate-dependent phosphoribosylglycinamide formyltransferase PurN:Superfamily II DNA/RNA helicases, SNF2 family:Glutaredoxin and related proteins:Cold shock proteins:Na+/H+-dicarboxylate symporters:S-adenosylmethionine decarboxylase:Ribosomal protein L25 (general stress protein Ctc):Phosphoenolpyruvate carboxykinase (ATP):Uncharacterized enzyme of thiazole biosynthesis:Peptide chain release factor RF-3:Amino acid transport and metabolism:Nucleotide transport and metabolism:Coenzyme transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:Replication, recombination and repair:Posttranslational modification, protein turnover, chaperones:Glycolysis / Gluconeogenesis:Citrate cycle (TCA cycle):Purine metabolism:Cysteine and methionine metabolism:Arginine and proline metabolism:Pyruvate metabolism:One carbon pool by folate:Thiamine metabolism:Aminoacyl-tRNA biosynthesis:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:Ribosome:TIGR00092:pckA:small_GTP:pth:PurN:ctc_TL5:purM:GRX_bact:SAM_DCase_Eco:Information storage and processing:Cellular processes and signaling:Metabolism:General:Unknown function:Ribosomal proteins: synthesis and modification:Other:Protein synthesis:Purine ribonucleotide biosynthesis:Purines, pyrimidines, nucleosides, and nucleotides:Glycolysis/gluconeogenesis:Electron transport:Energy metabolism:Polyamine biosynthesis:Metabolism:Global:Metabolism:Central intermediary metabolism:Translation:Genetic Information Processing:Metabolism of Cofactors and Vitamins:Amino Acid Metabolism:Nucleotide Metabolism:Carbohydrate Metabolism" 273 "Transaldolase:Fructose/tagatose bisphosphate aldolase:Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain:Carbonic anhydrase:FKBP-type peptidyl-prolyl cis-trans isomerases 1:Phosphatidylserine synthase:UDP-glucose pyrophosphorylase:Outer membrane protein and related peptidoglycan-associated (lipo)proteins:Negative regulator of sigma E activity:Positive regulator of sigma E activity:Uncharacterized protein conserved in bacteria:Periplasmic glucans biosynthesis protein:Uncharacterized protein conserved in bacteria:Carbohydrate transport and metabolism:Lipid transport and metabolism:Cell wall/membrane/envelope biogenesis:Posttranslational modification, protein turnover, chaperones:Inorganic ion transport and metabolism:Glycolysis / Gluconeogenesis:Pentose phosphate pathway:Pentose and glucuronate interconversions:Fructose and mannose metabolism:Galactose metabolism:Starch and sucrose metabolism:Amino sugar and nucleotide sugar metabolism:Glycerophospholipid metabolism:Methane metabolism:Nitrogen metabolism:Aminoacyl-tRNA biosynthesis:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:Function unknown:Signal transduction mechanisms:cbbA:talAB:galU:degP_htrA_DO:Poorly characterized:Carbohydrate Metabolism:Energy Metabolism:Lipid Metabolism:Genetic Information Processing:Translation:Global:Metabolism:Energy metabolism:Glycolysis/gluconeogenesis:Pentose phosphate pathway:Protein fate:Degradation of proteins, peptides, and glycopeptides:Cell envelope:Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides:Cellular processes and signaling:Metabolism:Metabolism" 274 "Energy production and conversion:tRNA and rRNA cytosine-C5-methylases:Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), B subunit:Methionyl-tRNA formyltransferase:N-formylmethionyl-tRNA deformylase:3-oxoacyl-(acyl-carrier-protein) synthase:K+ transport systems, NAD-binding component:ATPase involved in DNA replication initiation:5,10-methylenetetrahydrofolate reductase:Glycyl-tRNA synthetase, beta subunit:Heme/copper-type cytochrome/quinol oxidases, subunit 1:Recombinational DNA repair ATPase (RecF pathway):Aspartate/tyrosine/aromatic aminotransferase:Predicted periplasmic solute-binding protein:Heme/copper-type cytochrome/quinol oxidases, subunit 2:Heme/copper-type cytochrome/quinol oxidase, subunit 3:Heme/copper-type cytochrome/quinol oxidase, subunit 4:Amino acid transport and metabolism:Lipid transport and metabolism:Translation, ribosomal structure and biogenesis:Replication, recombination and repair:Inorganic ion transport and metabolism:Fatty acid biosynthesis:Oxidative phosphorylation:Cysteine and methionine metabolism:Tyrosine metabolism:Phenylalanine metabolism:Phenylalanine tyrosine and tryptophan biosynthesis:Novobiocin biosynthesis:One carbon pool by folate:Methane metabolism:Carbon fixation pathways in prokaryotes:Aminoacyl-tRNA biosynthesis:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:Two-component system:Homologous recombination:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:pept_deformyl:glyS:TIGR00247:DnaA:fmt:rsmB:recf:fadh2:gyrB:CyoA:CyoC:CyoB:CyoD:fabF:Information storage and processing:Metabolism:Poorly characterized:Metabolism:Global:Signal Transduction:Environmental Information Processing:Metabolism:Replication and Repair:Translation:Genetic Information Processing:Biosynthesis of Other Secondary Metabolites:Metabolism of Cofactors and Vitamins:Amino Acid Metabolism:Lipid Metabolism:Energy Metabolism:Energy metabolism:Electron transport:Fatty acid and phospholipid metabolism:Biosynthesis:DNA metabolism:DNA replication, recombination, and repair:Protein synthesis:tRNA aminoacylation:tRNA and rRNA base modification:Protein fate:Protein modification and repair:Hypothetical proteins:Conserved:Amino acid biosynthesis:Aspartate family" 275 "Flagellar biosynthesis pathway, component FlhA:Flagellar GTP-binding protein:Flagellar basal body rod protein:Flagellar hook-basal body protein:Flagellar basal-body P-ring protein:Flagellar hook protein FlgE:Flagellar biosynthesis/type III secretory pathway lipoprotein:Flagellar basal body protein:Flagellar hook capping protein:Flagellar basal body L-ring protein:Flagellar hook-length control protein:Rod binding protein:Flagellar basal body rod protein:Flagellar basal body rod protein:Signal transduction histidine kinase:Cell wall/membrane/envelope biogenesis:Cell motility:Posttranslational modification, protein turnover, chaperones:Flagellar assembly:Signal transduction mechanisms:fliE:fliF:FlgC:FlgB:FlhA:flgG_G_neg:flgF:flagell_FlgJ:FlhF:FlgEFG_subfam:Intracellular trafficking, secretion, and vesicular transport:Cellular processes and signaling:Cellular Processes:Cell Motility:Cellular processes:Chemotaxis and motility" 276 "Energy production and conversion:Ornithine carbamoyltransferase:Glycerophosphoryl diester phosphodiesterase:Fe2+/Zn2+ uptake regulation proteins:ABC-type Mn2+/Zn2+ transport systems, permease components:ABC-type Mn/Zn transport systems, ATPase component:Adenosine deaminase:Predicted permeases:Uncharacterized protein conserved in bacteria:ABC-type Zn2+ transport system, periplasmic component/surface adhesin:Amino acid transport and metabolism:Nucleotide transport and metabolism:Inorganic ion transport and metabolism:Purine metabolism:Arginine and proline metabolism:Glycerophospholipid metabolism:Metabolic pathways:Biosynthesis of secondary metabolites:ABC transporters:General function prediction only:Function unknown:orni_carb_tr:rarD:aden_deam:TIGR02448:Unknown substrate:Lipid Metabolism:Nucleotide Metabolism:Amino Acid Metabolism:Environmental Information Processing:Membrane Transport:Global:Metabolism:Transport and binding proteins:Metabolism:Amino acid biosynthesis:Glutamate family:Metabolism:Poorly characterized" 277 "Energy production and conversion:Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase:Ribonuclease HII:Ribosomal protein L17:Preprotein translocase subunit SecF:Preprotein translocase subunit SecD:Cobalamin-5-phosphate synthase:Fructose-2,6-bisphosphatase:Putative GTPases (G3E family):Lipid A disaccharide synthetase:Nitroreductase:Cobalamin biosynthesis protein CobD/CbiB:Cobyric acid synthase:Cobyrinic acid a,c-diamide synthase:NaMN:DMB phosphoribosyltransferase:Cobalamin biosynthesis protein CbiG:Precorrin isomerase:Adenosyl cobinamide kinase/adenosyl cobinamide phosphate guanylyltransferase:ATP:corrinoid adenosyltransferase:Precorrin-2 methylase:Amino acid transport and metabolism:Carbohydrate transport and metabolism:Coenzyme transport and metabolism:Translation, ribosomal structure and biogenesis:Replication, recombination and repair:Cell wall/membrane/envelope biogenesis:Lipopolysaccharide biosynthesis:Riboflavin metabolism:Porphyrin and chlorophyll metabolism:Metabolic pathways:Ribosome:DNA replication:Protein export:Bacterial secretion system:General function prediction only:L17:lpxB:cobQ:cobS:cobB:cobD:cobA:2A0604s01:L_thr_O3P_dcar:cobJ_cbiH:cobI_cbiL:CobW:BluB:cobT_DBIPRT:Intracellular trafficking, secretion, and vesicular transport:Heme, porphyrin, and cobalamin:Biosynthesis of cofactors, prosthetic groups, and carriers:Protein and peptide secretion and trafficking:Protein fate:Ribosomal proteins: synthesis and modification:Protein synthesis:Metabolism:Metabolism:Global:Membrane Transport:Environmental Information Processing:Replication and Repair:Folding Sorting and Degradation:Translation:Genetic Information Processing:Metabolism of Cofactors and Vitamins:Poorly characterized:Glycan Biosynthesis and Metabolism:Metabolism:Cellular processes and signaling:Information storage and processing:Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides:Cell envelope" 278 "Energy production and conversion:Methionine aminopeptidase:NAD synthase:Predicted GTPase:Threonyl-tRNA synthetase:NADPH:quinone reductase and related Zn-dependent oxidoreductases:Flavodoxins:Predicted endonuclease involved in recombination (possible Holliday junction resolvase in Mycoplasmas and B. subtilis):ADP-ribose pyrophosphatase:Nicotinic acid mononucleotide adenylyltransferase:Predicted nucleoside-diphosphate sugar epimerases:Predicted transcriptional regulator, consists of a Zn-ribbon and ATP-cone domains:Amidases related to nicotinamidase:Uncharacterized conserved protein:Nicotinic acid phosphoribosyltransferase:D-alanyl-D-alanine carboxypeptidase:GTPases:Predicted phosphotransferase related to Ser/Thr protein kinases:Nucleotide transport and metabolism:Carbohydrate transport and metabolism:Coenzyme transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:Replication, recombination and repair:Cell wall/membrane/envelope biogenesis:Nicotinate and nicotinamide metabolism:Nitrogen metabolism:Aminoacyl-tRNA biosynthesis:Metabolic pathways:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:Function unknown:cyt_tran_rel:TIGR00244:RNAse_H_YqgF:thrS:met_pdase_I:nadE:NAPRTase:adh_fam_1:GTP_HflX:GTPase_YsxC:Pyridine nucleotides:Energy Metabolism:Metabolism of Cofactors and Vitamins:Genetic Information Processing:Translation:Global:Metabolism:Energy metabolism:Fermentation:Regulatory functions:DNA interactions:Protein synthesis:Other:tRNA aminoacylation:Protein fate:Protein modification and repair:Unknown function:General:Biosynthesis of cofactors, prosthetic groups, and carriers:Metabolism:Information storage and processing:Cellular processes and signaling:Metabolism:Poorly characterized" 279 "Cold shock proteins:Large-conductance mechanosensitive channel:Uncharacterized conserved protein:Uncharacterized protein conserved in bacteria:Ribosome modulation factor:Uncharacterized conserved protein:Uncharacterized conserved protein:Translation, ribosomal structure and biogenesis:Transcription:Cell wall/membrane/envelope biogenesis:Function unknown:mscL:PHA_granule_1:cspD:Fatty acid and phospholipid metabolism:Information storage and processing:Poorly characterized:Cellular processes and signaling:Adaptations to atypical conditions:Cellular processes:Biosynthesis" 280 "Energy production and conversion:Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase]:Exonuclease III:Protease subunit of ATP-dependent Clp proteases:Uncharacterized conserved protein:Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM/CutM homologs:Subtilisin-like serine proteases:Metal-dependent amidase/aminoacylase/carboxypeptidase:Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL homologs:Uncharacterized protein (competence- and mitomycin-induced):Neutral trehalase:ATP-dependent DNA ligase:Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS/CutS homologs:Uncharacterized conserved protein:Methylase of polypeptide chain release factors:Topoisomerase IB:Predicted small integral membrane protein:Amino acid transport and metabolism:Carbohydrate transport and metabolism:Coenzyme transport and metabolism:Translation, ribosomal structure and biogenesis:Replication, recombination and repair:Posttranslational modification, protein turnover, chaperones:Purine metabolism:Phenylalanine metabolism:Starch and sucrose metabolism:Pyruvate metabolism:Metabolic pathways:Microbial metabolism in diverse environments:Base excision repair:Nucleotide excision repair:Mismatch repair:Non-homologous end-joining:General function prediction only:Function unknown:exoDNase_III:cinA_cterm:amidohydrolases:gshA_cyan_rel:Ku_bact:NHEJ_ligase_prk:Intracellular trafficking, secretion, and vesicular transport:Metabolism:Cellular processes and signaling:Information storage and processing:Degradation of proteins, peptides, and glycopeptides:Protein fate:DNA replication, recombination, and repair:DNA metabolism:Poorly characterized:Metabolism:Metabolism:Global:Replication and Repair:Genetic Information Processing:Amino Acid Metabolism:Nucleotide Metabolism:Carbohydrate Metabolism" 281 "Energy production and conversion:3-polyprenyl-4-hydroxybenzoate decarboxylase and related decarboxylases:Aspartate-semialdehyde dehydrogenase:Argininosuccinate synthase:Geranylgeranyl pyrophosphate synthase:Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases:dTDP-4-dehydrorhamnose reductase:Uncharacterized protein conserved in bacteria:Cytochrome c5:Tryptophan 2,3-dioxygenase (vermilion):Amino acid transport and metabolism:Coenzyme transport and metabolism:Cell wall/membrane/envelope biogenesis:Ubiquinone and other terpenoid-quinone biosynthesis:Alanine aspartate and glutamate metabolism:Glycine serine and threonine metabolism:Cysteine and methionine metabolism:Lysine biosynthesis:Arginine and proline metabolism:Tryptophan metabolism:Streptomycin biosynthesis:Polyketide sugar unit biosynthesis:Terpenoid backbone biosynthesis:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:Function unknown:argG:TIGR00148:dapE_proteo:asd_gamma:trp_2_3_diox:Cellular processes and signaling:Metabolism:Poorly characterized:Amino acid biosynthesis:General:Unknown function:Amino acids and amines:Energy metabolism:Metabolism:Global:Biosynthesis of Other Secondary Metabolites:Metabolism:Metabolism of Terpenoids and Polyketides:Metabolism of Cofactors and Vitamins:Aspartate family:Amino Acid Metabolism:Glutamate family" 282 "Ribosomal protein S8:Nucleoside diphosphate kinase:Translation elongation factor P (EF-P)/translation initiation factor 5A (eIF-5A):Transcription antiterminator:RNase P protein component:Preprotein translocase subunit SecE:Acetyl-CoA carboxylase beta subunit:Preprotein translocase subunit SecG:Uncharacterized paraquat-inducible protein B:Nucleotide transport and metabolism:Lipid transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:Fatty acid biosynthesis:Purine metabolism:Pyrimidine metabolism:Pyruvate metabolism:Propanoate metabolism:Carbon fixation pathways in prokaryotes:Aminoacyl-tRNA biosynthesis:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:Ribosome:Protein export:Bacterial secretion system:Function unknown:efp:rnpA:accD:secG:nusG:secE_bact:rpmH_bact:Intracellular trafficking, secretion, and vesicular transport:Poorly characterized:Membrane Transport:Environmental Information Processing:Folding Sorting and Degradation:Metabolism:Translation:Genetic Information Processing:Nucleotide Metabolism:Lipid Metabolism:Energy Metabolism:Global:Carbohydrate Metabolism:Metabolism:Fatty acid and phospholipid metabolism:Biosynthesis:Transcription:Transcription factors:RNA processing:Protein synthesis:Ribosomal proteins: synthesis and modification:Translation factors:Protein fate:Protein and peptide secretion and trafficking:Information storage and processing:Cellular processes and signaling:Metabolism" 283 "Integral membrane protein possibly involved in chromosome condensation:Lactoylglutathione lyase and related lyases:Fructose-2,6-bisphosphatase:Transcriptional regulator:Predicted permeases:Membrane proteins related to metalloendopeptidases:Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain:ADP-ribose pyrophosphatase:ABC-type multidrug transport system, ATPase component:Putative threonine efflux protein:Transcriptional regulator:Acyl-CoA hydrolase:Predicted hydrolases of HD superfamily:Acyl-CoA dehydrogenases:Membrane transporters of cations and cationic drugs:Arabinose efflux permease:Negative regulator of beta-lactamase expression:Uncharacterized protein conserved in bacteria:Predicted O-methyltransferase:Signal transduction histidine kinase involved in nitrogen fixation and metabolism regulation:Cell cycle control, cell division, chromosome partitioning:Amino acid transport and metabolism:Nucleotide transport and metabolism:Carbohydrate transport and metabolism:Lipid transport and metabolism:Transcription:Cell wall/membrane/envelope biogenesis:Inorganic ion transport and metabolism:Geraniol degradation:Naphthalene degradation:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:ABC transporters:Two-component system:General function prediction only:Function unknown:Signal transduction mechanisms:crcB:cztR_silR_copR:Defense mechanisms:Information storage and processing:General:Unknown function:Metabolism:Global:Signal Transduction:Membrane Transport:Environmental Information Processing:Xenobiotics Biodegradation and Metabolism:Metabolism:Metabolism of Terpenoids and Polyketides:Poorly characterized:Metabolism:Cellular processes and signaling" 284 "Non-ribosomal peptide synthetase modules and related proteins:Peptide arylation enzymes:ABC-type multidrug transport system, ATPase and permease components:Isochorismate synthase:Chorismate mutase:Uncharacterized iron-regulated membrane protein:Predicted thioesterase involved in non-ribosomal peptide biosynthesis:Oxidoreductase (NAD-binding), involved in siderophore biosynthesis:Outer membrane receptor for ferric coprogen and ferric-rhodotorulic acid:Amino acid transport and metabolism:Coenzyme transport and metabolism:Inorganic ion transport and metabolism:Ubiquinone and other terpenoid-quinone biosynthesis:Biosynthesis of siderophore group nonribosomal peptides:Metabolic pathways:Biosynthesis of secondary metabolites:ABC transporters:Secondary metabolites biosynthesis, transport and catabolism:Function unknown:isochor_syn:AA-adenyl-dom:thiaz-red:TonB-siderophor:CM-like:sider_RhtX_FptX:Defense mechanisms:Poorly characterized:Metabolism of Cofactors and Vitamins:Metabolism of Terpenoids and Polyketides:Environmental Information Processing:Membrane Transport:Global:Metabolism:Transport and binding proteins:Cations and iron carrying compounds:Porins:Biosynthesis of cofactors, prosthetic groups, and carriers:Menaquinone and ubiquinone:Cellular processes and signaling:Metabolism:Metabolism" 285 "Energy production and conversion:Glutamate-1-semialdehyde aminotransferase:Dihydroorotate dehydrogenase:NADPH-dependent glutamate synthase beta chain and related oxidoreductases:Amino acid transporters:Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily):Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases):Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases:FOG: EAL domain:Sugar phosphate permease:Choline dehydrogenase and related flavoproteins:Na+-transporting NADH:ubiquinone oxidoreductase, subunit NqrF:P pilus assembly protein, chaperone PapD:ABC-type arginine transport system, permease component:Protein involved in meta-pathway of phenol degradation:ABC-type histidine transport system, ATPase component:Phenylpropionate dioxygenase and related ring-hydroxylating dioxygenases, large terminal subunit:L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily:Small subunit of phenylpropionate dioxygenase:Amino acid transport and metabolism:Nucleotide transport and metabolism:Carbohydrate transport and metabolism:Coenzyme transport and metabolism:Lipid transport and metabolism:Cell wall/membrane/envelope biogenesis:Cell motility:Inorganic ion transport and metabolism:Fatty acid biosynthesis:Pyrimidine metabolism:Alanine aspartate and glutamate metabolism:Benzoate degradation:Fluorobenzoate degradation:beta-Alanine metabolism:Xylene degradation:Pantothenate and CoA biosynthesis:Porphyrin and chlorophyll metabolism:Nitrogen metabolism:Biosynthesis of unsaturated fatty acids:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:ABC transporters:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:Signal transduction mechanisms:pyrD_sub1_fam:HEQRo_perm_3TM:protocat_pcaD:benzo_1_2_benA:benzo_1_2_benB:FMN_nitrolo:Intracellular trafficking, secretion, and vesicular transport:Nucleotide Metabolism:Lipid Metabolism:Other:Energy Metabolism:Transport and binding proteins:Amino acids, peptides and amines:Unknown function:Enzymes of unknown specificity:Cellular processes and signaling:Metabolism:Poorly characterized:Energy metabolism:Metabolism:Global:Membrane Transport:Environmental Information Processing:Metabolism:Xenobiotics Biodegradation and Metabolism:Metabolism of Cofactors and Vitamins:Metabolism of Other Amino Acids:Amino Acid Metabolism" 286 "Glutamyl- and glutaminyl-tRNA synthetases:Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase:Thiamine monophosphate synthase:Aspartate/tyrosine/aromatic aminotransferase:Leucyl-tRNA synthetase:Phosphoserine phosphatase:Adenylate kinase and related kinases:Phosphatidylserine decarboxylase:Flagellar motor component:Flagellar motor protein:DnaK suppressor protein:Rhodanese-related sulfurtransferase:Uncharacterized protein conserved in bacteria:Amino acid transport and metabolism:Nucleotide transport and metabolism:Coenzyme transport and metabolism:Lipid transport and metabolism:Translation, ribosomal structure and biogenesis:Cell motility:Inorganic ion transport and metabolism:Purine metabolism:Glycine serine and threonine metabolism:Cysteine and methionine metabolism:Valine leucine and isoleucine biosynthesis:Glycerophospholipid metabolism:Methane metabolism:Thiamine metabolism:Aminoacyl-tRNA biosynthesis:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:Two-component system:Bacterial chemotaxis:Flagellar assembly:Sulfur relay system:Function unknown:Signal transduction mechanisms:PS_decarb:leuS_bact:thiE:adk:HSK-PSP:dksA:TIGR02448:MotA1:queuosine_YadB:tRNA aminoacylation:tRNA and rRNA base modification:Biosynthesis of cofactors, prosthetic groups, and carriers:Thiamine:Information storage and processing:Cellular processes and signaling:Metabolism:Poorly characterized:Protein synthesis:Small molecule interactions:Regulatory functions:Nucleotide and nucleoside interconversions:Purines, pyrimidines, nucleosides, and nucleotides:Biosynthesis:Fatty acid and phospholipid metabolism:Metabolism:Metabolism:Global:Cell Motility:Cellular Processes:Signal Transduction:Environmental Information Processing:Folding Sorting and Degradation:Translation:Genetic Information Processing:Metabolism of Cofactors and Vitamins:Amino Acid Metabolism:Nucleotide Metabolism:Lipid Metabolism:Energy Metabolism" 287 "Energy production and conversion:Asparagine synthase (glutamine-hydrolyzing):Protein-tyrosine-phosphatase:Predicted flavoprotein:Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily):Predicted transcriptional regulators:Na+/H+ antiporter NhaD and related arsenite permeases:Zn-dependent alcohol dehydrogenases:DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog:Outer membrane receptor proteins, mostly Fe transport:Acyl-CoA dehydrogenases:Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases:AraC-type DNA-binding domain-containing proteins:Sugar phosphate permease:Arabinose efflux permease:Fe2+-dicitrate sensor, membrane component:Small subunit of phenylpropionate dioxygenase:Amino acid transport and metabolism:Carbohydrate transport and metabolism:Lipid transport and metabolism:Transcription:Inorganic ion transport and metabolism:Alanine aspartate and glutamate metabolism:Chlorocyclohexane and chlorobenzene degradation:Chloroalkane and chloroalkene degradation:Nitrogen metabolism:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:RNA polymerase:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:Signal transduction mechanisms:2a45:asn_synth_AEB:resist_ArsH:sigma70-ECF:sulfur_SfnB:Sulfur metabolism:Central intermediary metabolism:Metabolism:Metabolism:Global:Transcription:Genetic Information Processing:Xenobiotics Biodegradation and Metabolism:Amino Acid Metabolism:Aspartate family:Energy Metabolism:Information storage and processing:Cellular processes and signaling:Metabolism:Poorly characterized:Amino acid biosynthesis:Detoxification:Cellular processes:Other:Transport and binding proteins" 288 "Putative translation initiation inhibitor, yjgF family:Carbonic anhydrase:Transcriptional regulator:Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases):Uncharacterized conserved protein:Cyanate lyase:Pirin-related protein:Sugar phosphate permease:Uncharacterized protein, possibly involved in utilization of glycolate and propanediol:Uncharacterized protein conserved in bacteria:O-Methyltransferase involved in polyketide biosynthesis:Uncharacterized protein conserved in bacteria:Outer membrane receptor for monomeric catechols:Carbohydrate transport and metabolism:Lipid transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:Inorganic ion transport and metabolism:Fatty acid metabolism:Nitrogen metabolism:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:Function unknown:cynS:TonB-siderophor:Energy Metabolism:Metabolism:Poorly characterized:Metabolism:Information storage and processing:Detoxification:Cellular processes:Porins:Transport and binding proteins:Lipid Metabolism" 289 "Energy production and conversion:Predicted amidohydrolase:FOG: Ankyrin repeat:Uncharacterized membrane protein, putative virulence factor:ABC-type amino acid transport/signal transduction systems, periplasmic component/domain:Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases):NADH dehydrogenase, FAD-containing subunit:Transcriptional regulator:ABC-type metal ion transport system, periplasmic component/surface antigen:Outer membrane receptor proteins, mostly Fe transport:Acyl-CoA dehydrogenases:FOG: HPt domain:Uncharacterized conserved protein:Aromatic ring hydroxylase:Uncharacterized conserved protein:Uncharacterized protein conserved in bacteria:ABC-type protease/lipase transport system, ATPase and permease components:Predicted signal transduction protein containing sensor and EAL domains:Amino acid transport and metabolism:Lipid transport and metabolism:Transcription:Inorganic ion transport and metabolism:Oxidative phosphorylation:ABC transporters:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:Function unknown:Signal transduction mechanisms:type_I_sec_PrtD:PPK2_P_aer:sulfur_SfnB:Membrane Transport:Environmental Information Processing:Energy Metabolism:Metabolism:Poorly characterized:Metabolism:Cellular processes and signaling:Information storage and processing:Protein and peptide secretion and trafficking:Protein fate:Sulfur metabolism:Phosphorus compounds:Central intermediary metabolism" 290 "Energy production and conversion:Thiol-disulfide isomerase and thioredoxins:Transcriptional regulator:Cytosine/adenosine deaminases:Signal transduction histidine kinase:Mannose-6-phosphate isomerase:FOG: Ankyrin repeat:Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain:L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases:Protein-disulfide isomerase:Cytochrome c, mono- and diheme variants:Cytochrome P450:Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases:AraC-type DNA-binding domain-containing proteins:Choline dehydrogenase and related flavoproteins:Cyanate permease:Uncharacterized protein conserved in bacteria:Thiol:disulfide interchange protein:Amino acid transport and metabolism:Nucleotide transport and metabolism:Carbohydrate transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:Posttranslational modification, protein turnover, chaperones:Inorganic ion transport and metabolism:Pentose phosphate pathway:Bisphenol degradation:Pyruvate metabolism:Polycyclic aromatic hydrocarbon degradation:Aminobenzoate degradation:Limonene and pinene degradation:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:Function unknown:Signal transduction mechanisms:FMN_nitrolo:Cellular processes and signaling:Information storage and processing:Enzymes of unknown specificity:Unknown function:Metabolism:Global:Xenobiotics Biodegradation and Metabolism:Metabolism of Terpenoids and Polyketides:Carbohydrate Metabolism:Metabolism:Poorly characterized:Metabolism" 291 "Energy production and conversion:Glycine/D-amino acid oxidases (deaminating):Flavodoxin reductases (ferredoxin-NADPH reductases) family 1:Threonine dehydratase:Choline-glycine betaine transporter:Transcriptional regulator:Predicted ATPase:K+-transporting ATPase, A chain:Uncharacterized iron-regulated membrane protein:Nucleoside 2-deoxyribosyltransferase:Amino acid transport and metabolism:Nucleotide transport and metabolism:Transcription:Cell wall/membrane/envelope biogenesis:Inorganic ion transport and metabolism:Glycine serine and threonine metabolism:Valine leucine and isoleucine biosynthesis:Arginine and proline metabolism:Metabolic pathways:Biosynthesis of secondary metabolites:Two-component system:General function prediction only:Function unknown:kdpA:bcct:ilvA_2Cterm:Information storage and processing:Amino Acid Metabolism:Environmental Information Processing:Signal Transduction:Global:Metabolism:Transport and binding proteins:Cations and iron carrying compounds:Other:Amino acid biosynthesis:Pyruvate family:Metabolism:Cellular processes and signaling:Metabolism:Poorly characterized" 292 "Energy production and conversion:Asparagine synthase (glutamine-hydrolyzing):Co/Zn/Cd efflux system component:Transglutaminase-like enzymes, putative cysteine proteases:Uncharacterized conserved protein:Acyl-CoA dehydrogenases:Arylamine N-acetyltransferase:FOG: GGDEF domain:Uncharacterized conserved protein:DNA-binding HTH domain-containing proteins:Protocatechuate 3,4-dioxygenase beta subunit:Uncharacterized protein conserved in bacteria:Predicted membrane protein:Predicted membrane protein:Protein involved in meta-pathway of phenol degradation:Predicted RNA polymerase sigma factor containing a TPR repeat domain:Amino acid transport and metabolism:Lipid transport and metabolism:Transcription:Inorganic ion transport and metabolism:Fatty acid metabolism:Alanine aspartate and glutamate metabolism:Valine leucine and isoleucine degradation:Benzoate degradation:beta-Alanine metabolism:Polycyclic aromatic hydrocarbon degradation:Aminobenzoate degradation:Propanoate metabolism:Nitrogen metabolism:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:RNA polymerase:Secondary metabolites biosynthesis, transport and catabolism:Function unknown:Signal transduction mechanisms:sensory_box:GGDEF:CDF:asn_synth_AEB:protocat_beta:sigma70-ECF:Cellular processes and signaling:Carbohydrate Metabolism:Energy Metabolism:Lipid Metabolism:Amino Acid Metabolism:Metabolism of Other Amino Acids:Xenobiotics Biodegradation and Metabolism:Genetic Information Processing:Transcription:Global:Metabolism:Energy metabolism:Other:Regulatory functions:Small molecule interactions:Transport and binding proteins:Cations and iron carrying compounds:Amino acid biosynthesis:Aspartate family:Signal transduction:Other:Information storage and processing:Metabolism:Metabolism:Poorly characterized" 293 "Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), B subunit:Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II:Zn-dependent oligopeptidases:Predicted phosphatases:Phosphoserine phosphatase:Carbonic anhydrases/acetyltransferases, isoleucine patch superfamily:dTDP-D-glucose 4,6-dehydratase:ABC-type Fe3+ transport system, permease component:Predicted sugar nucleotidyltransferases:Flagellar hook-associated protein:Flagellin and related hook-associated proteins:ABC-type Fe3+ transport system, periplasmic component:Putative glycosyl/glycerophosphate transferases involved in teichoic acid biosynthesis TagF/TagB/EpsJ/RodC:Threonine aldolase:2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase:Predicted nucleic-acid-binding protein containing a Zn-ribbon domain:Amino acid transport and metabolism:Coenzyme transport and metabolism:Lipid transport and metabolism:Replication, recombination and repair:Cell wall/membrane/envelope biogenesis:Cell motility:Inorganic ion transport and metabolism:Fatty acid metabolism:Ubiquinone and other terpenoid-quinone biosynthesis:Glycine serine and threonine metabolism:Streptomycin biosynthesis:Polyketide sugar unit biosynthesis:Glyoxylate and dicarboxylate metabolism:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:ABC transporters:Flagellar assembly:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:gyrB:dTDP_gluc_dehyt:HAD-SF-IB:UbiG:TIGR02231:TIGR02443:flgK_ends:flagell_flgL:Cellular processes and signaling:Carbohydrate Metabolism:Lipid Metabolism:Amino Acid Metabolism:Metabolism of Cofactors and Vitamins:Metabolism of Terpenoids and Polyketides:Biosynthesis of Other Secondary Metabolites:Environmental Information Processing:Membrane Transport:Cellular Processes:Cell Motility:Global:Metabolism:DNA metabolism:DNA replication, recombination, and repair:Cellular processes:Chemotaxis and motility:Unknown function:Enzymes of unknown specificity:Biosynthesis of cofactors, prosthetic groups, and carriers:Menaquinone and ubiquinone:Cell envelope:Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides:Information storage and processing:Metabolism:Metabolism:Poorly characterized" 294 "Acetyl-CoA acetyltransferase:Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II:Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases:Predicted Na+-dependent transporter:Predicted amidohydrolase:Amino acid transporters:Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily):ABC-type branched-chain amino acid transport systems, periplasmic component:Spermidine/putrescine-binding periplasmic protein:Glycine cleavage system protein P (pyridoxal-binding), C-terminal domain:Long-chain acyl-CoA synthetases (AMP-forming):3-hydroxyacyl-CoA dehydrogenase:Acyl-CoA dehydrogenases:DNA-binding HTH domain-containing proteins:L-aminopeptidase/D-esterase:Response regulator with putative antiterminator output domain:Predicted membrane protein:Uncharacterized protein conserved in bacteria:Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain:Amino acid transport and metabolism:Lipid transport and metabolism:Transcription:Fatty acid metabolism:Synthesis and degradation of ketone bodies:Glycine serine and threonine metabolism:Valine leucine and isoleucine degradation:Geraniol degradation:Lysine degradation:Arginine and proline metabolism:Phenylalanine metabolism:Benzoate degradation:Tryptophan metabolism:beta-Alanine metabolism:Cyanoamino acid metabolism:Pyruvate metabolism:Aminobenzoate degradation:Glyoxylate and dicarboxylate metabolism:Propanoate metabolism:Styrene degradation:Butanoate metabolism:Carbon fixation pathways in prokaryotes:Terpenoid backbone biosynthesis:Limonene and pinene degradation:Caprolactam degradation:Biosynthesis of unsaturated fatty acids:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:ABC transporters:Two-component system:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:Function unknown:Signal transduction mechanisms:gcvP:ac_ac_CoA_syn:AcCoA-C-Actrans:Carbohydrate Metabolism:Signal Transduction:Global:Metabolism:Central intermediary metabolism:Other:Energy metabolism:Amino acids and amines:Fatty acid and phospholipid metabolism:Other:Information storage and processing:Cellular processes and signaling:Metabolism:Poorly characterized:Membrane Transport:Environmental Information Processing:Xenobiotics Biodegradation and Metabolism:Metabolism of Terpenoids and Polyketides:Metabolism:Metabolism of Other Amino Acids:Amino Acid Metabolism:Lipid Metabolism:Energy Metabolism" 295 "Energy production and conversion:3-polyprenyl-4-hydroxybenzoate decarboxylase and related decarboxylases:Uncharacterized NAD(FAD)-dependent dehydrogenases:Zn-dependent hydrolases, including glyoxylases:Glycerol kinase:Predicted dehydrogenase:Transcriptional regulator:Universal stress protein UspA and related nucleotide-binding proteins:Na+/proline symporter:Predicted phosphatase/phosphohexomutase:Signal transduction histidine kinase:Kef-type K+ transport systems, predicted NAD-binding component:Phosphatidylserine/phosphatidylglycerophosphate/cardiolipin synthases and related enzymes:Multidrug resistance efflux pump:Predicted hydrolases of HD superfamily:GAF domain-containing protein:Malate/L-lactate dehydrogenases:Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS/CutS homologs:Putative NADP-dependent oxidoreductases:AraC-type DNA-binding domain-containing proteins:Predicted phosphosugar isomerases:DNA-binding HTH domain-containing proteins:Streptomycin 6-kinase:Uncharacterized component of phosphonate metabolism:Uncharacterized protein conserved in bacteria:Signal transduction histidine kinase:Predicted ester cyclase:Amino acid transport and metabolism:Coenzyme transport and metabolism:Lipid transport and metabolism:Transcription:Cell wall/membrane/envelope biogenesis:Inorganic ion transport and metabolism:Pentose phosphate pathway:Purine metabolism:Phosphonate and phosphinate metabolism:Glycerolipid metabolism:Metabolic pathways:Microbial metabolism in diverse environments:General function prediction only:Function unknown:Signal transduction mechanisms:TIGR00148:sensory_box:phosphonatase:phosphon_PhnN:Defense mechanisms:Metabolism of Other Amino Acids:Central intermediary metabolism:Nucleotide Metabolism:Other:Lipid Metabolism:Carbohydrate Metabolism:Metabolism:Poorly characterized:Metabolism:Cellular processes and signaling:Information storage and processing:General:Unknown function:Small molecule interactions:Phosphorus compounds:Regulatory functions:Metabolism:Global" 296 "Porphobilinogen deaminase:23S rRNA methylase:Lactoylglutathione lyase and related lyases:Glycosyltransferases involved in cell wall biogenesis:Predicted phosphatases:Pseudouridylate synthases, 23S RNA-specific:Signal transduction histidine kinase:Flagellar biosynthesis/type III secretory pathway ATPase:Flagellar biosynthesis pathway, component FliP:Flagellar basal body-associated protein:Uroporphyrinogen-III synthase:Uncharacterized protein conserved in bacteria:DNA segregation ATPase FtsK/SpoIIIE and related proteins:Flagellar biosynthesis pathway, component FliR:Transcriptional regulators:Flagellar motor switch protein:Flagellar motor switch/type III secretory pathway protein:Flagellar biosynthesis pathway, component FliQ:Bacterioferritin (cytochrome b1):Flagellar biogenesis protein:Putative Zn-dependent protease:Cell cycle control, cell division, chromosome partitioning:Amino acid transport and metabolism:Coenzyme transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:Cell wall/membrane/envelope biogenesis:Cell motility:Inorganic ion transport and metabolism:Pyruvate metabolism:Glyoxylate and dicarboxylate metabolism:Porphyrin and chlorophyll metabolism:Aminoacyl-tRNA biosynthesis:Metabolic pathways:Biosynthesis of secondary metabolites:Bacterial chemotaxis:Flagellar assembly:General function prediction only:Function unknown:Signal transduction mechanisms:rluA_subfam:glyox_I:hemC:bfr:fliI_yscN:fliP:fliM_switch:fliR:fliQ:HAD-SF-IA-v3:fliN:FliO_TIGR:Intracellular trafficking, secretion, and vesicular transport:Enzymes of unknown specificity:Carbohydrate Metabolism:Metabolism of Cofactors and Vitamins:Genetic Information Processing:Translation:Cellular Processes:Cell Motility:Global:Metabolism:Energy metabolism:ATP-proton motive force interconversion:Other:Protein synthesis:tRNA and rRNA base modification:Transport and binding proteins:Cations and iron carrying compounds:Cellular processes:Chemotaxis and motility:Unknown function:Metabolism:Biosynthesis of cofactors, prosthetic groups, and carriers:Heme, porphyrin, and cobalamin:Information storage and processing:Cellular processes and signaling:Metabolism:Poorly characterized" 297 "Predicted dehydrogenases and related proteins:UDP-N-acetyl-D-mannosaminuronate dehydrogenase:Predicted acyltransferases:Protein involved in cell division:Large exoproteins involved in heme utilization or adhesion:Chain length determinant protein:Superfamily I DNA and RNA helicases:Cell cycle control, cell division, chromosome partitioning:Lipid transport and metabolism:Cell wall/membrane/envelope biogenesis:Aminoacyl-tRNA biosynthesis:General function prediction only:DOC_P1:fil_hemag_20aa:NDP-sugDHase:Intracellular trafficking, secretion, and vesicular transport:Translation:Metabolism:Poorly characterized:Genetic Information Processing:General:Unknown function:Cellular processes and signaling" 298 "Phage tail sheath protein FI:Phage tail tube protein FII:Phage protein U:Phage protein D:Phage baseplate assembly protein W:Mu-like prophage protein:Phage-related baseplate assembly protein:Bacteriophage P2-related tail formation protein:Phage P2 baseplate assembly protein gpV:P2-like prophage tail protein X:Phage-related tail fibre protein:General function prediction only:tail_tube:tail_P2_I:phage_P2_V:Mobile and extrachromosomal element functions:Poorly characterized:Prophage functions" 299 "Uncharacterized conserved protein:Biotin-(acetyl-CoA carboxylase) ligase:Predicted epimerase, PhzC/PhzF homolog:Nucleotidyltransferase/DNA polymerase involved in DNA repair:Nucleotide-binding protein implicated in inhibition of septum formation:Transcriptional regulator:Single-stranded DNA-specific exonuclease:Predicted Fe-S-cluster redox enzyme:Predicted branched-chain amino acid permease (azaleucine resistance):Transcriptional regulator:Uncharacterized conserved protein:Uncharacterized bacitracin resistance protein:Uncharacterized protein, possibly involved in aromatic compounds catabolism:Predicted membrane protein:Uncharacterized conserved protein:Endonuclease I:Arabinose efflux permease:Uncharacterized protein conserved in bacteria:NhaP-type Na+/H+ and K+/H+ antiporters with a unique C-terminal domain:Cell cycle control, cell division, chromosome partitioning:Amino acid transport and metabolism:Carbohydrate transport and metabolism:Coenzyme transport and metabolism:Transcription:Replication, recombination and repair:Inorganic ion transport and metabolism:Peptidoglycan biosynthesis:Biotin metabolism:Aminoacyl-tRNA biosynthesis:Metabolic pathways:Ribosome:Base excision repair:Mismatch repair:Homologous recombination:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:Function unknown:YaeB_AF0241:birA_ligase:maf:unchar_dom_1:YbgI_SA1388:recJ:PhzF_family:efflux_Bcr_CflA:undec_PP_bacA:Defense mechanisms:Toxin production and resistance:Cell division:Cellular processes:Protein modification and repair:Protein fate:DNA replication, recombination, and repair:DNA metabolism:Metabolism:Metabolism:Global:Replication and Repair:Translation:Genetic Information Processing:Metabolism of Cofactors and Vitamins:Cellular processes and signaling:Glycan Biosynthesis and Metabolism:Metabolism:Poorly characterized:Information storage and processing:Biosynthesis and degradation of murein sacculus and peptidoglycan:Cell envelope:General:Enzymes of unknown specificity:Unknown function" 300 "Glycosyltransferase:Glycosyltransferases involved in cell wall biogenesis:Mannose-1-phosphate guanylyltransferase:Periplasmic protein involved in polysaccharide export:Sugar transferases involved in lipopolysaccharide synthesis:Uncharacterized protein involved in exopolysaccharide biosynthesis:Tfp pilus assembly protein, tip-associated adhesin PilY1:Fucose 4-O-acetylase and related acetyltransferases:Beta-xylosidase:Tfp pilus assembly protein PilX:Tfp pilus assembly protein PilW:Tfp pilus assembly protein PilV:Tfp pilus assembly protein PilE:Tfp pilus assembly protein FimT:Carbohydrate transport and metabolism:Cell wall/membrane/envelope biogenesis:Cell motility:Fructose and mannose metabolism:Starch and sucrose metabolism:Amino sugar and nucleotide sugar metabolism:Metabolic pathways:Biosynthesis of secondary metabolites:GMP_PMI:type_IV_pilV:IV_pilin_GFxxxE:WcaJ_sugtrans:Intracellular trafficking, secretion, and vesicular transport:Metabolism:Carbohydrate Metabolism:Global:Metabolism:Protein fate:Protein and peptide secretion and trafficking:Protein modification and repair:Cell envelope:Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides:Cellular processes and signaling:Metabolism" 301 "Energy production and conversion:ABC-type nitrate/sulfonate/bicarbonate transport system, permease component:ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components:ABC-type amino acid transport system, permease component:ABC-type amino acid transport/signal transduction systems, periplasmic component/domain:ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component:ABC-type polar amino acid transport system, ATPase component:Acyl-CoA dehydrogenases:Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases:Probable taurine catabolism dioxygenase:Isopenicillin N synthase and related dioxygenases:Molybdopterin-binding protein:ABC-type taurine transport system, periplasmic component:ABC-type taurine transport system, ATPase component:Amino acid transport and metabolism:Coenzyme transport and metabolism:Lipid transport and metabolism:Inorganic ion transport and metabolism:Taurine and hypotaurine metabolism:ABC transporters:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:Signal transduction mechanisms:Mop:HEQRo_perm_3TM:SsuA_fam:taurine_ABC_bnd:alk_sulf_monoox:Anions:Amino acids, peptides and amines:Transport and binding proteins:Sulfur metabolism:Central intermediary metabolism:Membrane Transport:Environmental Information Processing:Metabolism:Metabolism of Other Amino Acids:Poorly characterized:Metabolism:Cellular processes and signaling:Other" 302 "ABC-type phosphate transport system, periplasmic component:Signal transduction histidine kinase:Predicted UDP-glucose 6-dehydrogenase:Metal-dependent hydrolases of the beta-lactamase superfamily I:Transcriptional regulators:Uncharacterized conserved protein:Putative hemolysin:Predicted phosphatase:ABC-type phosphate/phosphonate transport system, periplasmic component:Phosphodiesterase/alkaline phosphatase D:Uncharacterized enzyme of phosphonate metabolism:Phosphate-selective porin:Predicted HD phosphohydrolase:ABC-type uncharacterized transport system, permease component:ABC-type phosphonate transport system, ATPase component:Transcription:Cell wall/membrane/envelope biogenesis:Inorganic ion transport and metabolism:Pentose and glucuronate interconversions:Ascorbate and aldarate metabolism:Starch and sucrose metabolism:Amino sugar and nucleotide sugar metabolism:Aminobenzoate degradation:Folate biosynthesis:Aminoacyl-tRNA biosynthesis:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:ABC transporters:Two-component system:General function prediction only:Function unknown:Signal transduction mechanisms:3A0109s03R:CP_lyasePhnL:C_P_lyase_phnF:NDP-sugDHase:Phn-HD:PhnG_redo:PhnP:PPK2_P_aer:Cellular processes and signaling:Carbohydrate Metabolism:Metabolism of Cofactors and Vitamins:Xenobiotics Biodegradation and Metabolism:Genetic Information Processing:Translation:Environmental Information Processing:Membrane Transport:Signal Transduction:Global:Metabolism:Central intermediary metabolism:Phosphorus compounds:Regulatory functions:DNA interactions:Transport and binding proteins:Anions:Information storage and processing:Metabolism:Metabolism:Poorly characterized" 303 "Energy production and conversion:Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase]:Cysteine synthase:Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2:Transcriptional regulator:ABC-type nitrate/sulfonate/bicarbonate transport system, permease component:Mannose-6-phosphate isomerase:ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components:NAD-dependent aldehyde dehydrogenases:Enoyl-CoA hydratase/carnithine racemase:Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases):Serine acetyltransferase:ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component:Transcriptional regulator:Type II secretory pathway, component PulD:Predicted dinucleotide-utilizing enzyme:Acyl-CoA dehydrogenases:Arabinose efflux permease:Predicted metal-dependent hydrolases related to alanyl-tRNA synthetase HxxxH domain:Amino acid transport and metabolism:Carbohydrate transport and metabolism:Coenzyme transport and metabolism:Lipid transport and metabolism:Transcription:Cell motility:Inorganic ion transport and metabolism:Fatty acid metabolism:Glycine serine and threonine metabolism:Cysteine and methionine metabolism:Valine leucine and isoleucine degradation:Geraniol degradation:Lysine degradation:Benzoate degradation:Tryptophan metabolism:beta-Alanine metabolism:Selenocompound metabolism:Aminobenzoate degradation:Propanoate metabolism:Butanoate metabolism:Nicotinate and nicotinamide metabolism:Limonene and pinene degradation:Sulfur metabolism:Caprolactam degradation:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:ABC transporters:Bacterial secretion system:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:Intracellular trafficking, secretion, and vesicular transport:Cellular processes and signaling:Information storage and processing:Metabolism:Metabolism:Global:Metabolism:Poorly characterized:Membrane Transport:Environmental Information Processing:Xenobiotics Biodegradation and Metabolism:Metabolism of Terpenoids and Polyketides:Metabolism of Cofactors and Vitamins:Metabolism of Other Amino Acids:Amino Acid Metabolism:Lipid Metabolism:Energy Metabolism:Carbohydrate Metabolism" 304 "Energy production and conversion:Mannitol-1-phosphate/altronate dehydrogenases:ABC-type sugar transport system, permease component:Zn-dependent protease with chaperone function:Glutathione S-transferase:Sugar (pentulose and hexulose) kinases:ABC-type sugar transport systems, permease components:Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain:Acyl-CoA dehydrogenases:Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases:Sugar phosphate permease:Arabinose efflux permease:Uncharacterized iron-regulated membrane protein:Protein involved in meta-pathway of phenol degradation:Carbohydrate transport and metabolism:Lipid transport and metabolism:Transcription:Posttranslational modification, protein turnover, chaperones:Pentose and glucuronate interconversions:Fructose and mannose metabolism:Metabolic pathways:ABC transporters:Function unknown:Signal transduction mechanisms:maiA:XylB:alk_sulf_monoox:FMN_nitrolo:sulfur_SfnB:Cellular processes and signaling:Carbohydrate Metabolism:Environmental Information Processing:Membrane Transport:Global:Metabolism:Central intermediary metabolism:Sulfur metabolism:Energy metabolism:Amino acids and amines:Sugars:Unknown function:Enzymes of unknown specificity:Information storage and processing:Metabolism:Metabolism:Poorly characterized" 305 "Energy production and conversion:Polyprenyltransferase (cytochrome oxidase assembly factor):Fe-S oxidoreductase:FAD/FMN-containing dehydrogenases:Heme/copper-type cytochrome/quinol oxidases, subunit 1:Uncharacterized protein required for cytochrome oxidase assembly:Heme/copper-type cytochrome/quinol oxidases, subunit 2:Heme/copper-type cytochrome/quinol oxidase, subunit 3:Transcriptional regulators:FOG: GGDEF domain:Cytochrome oxidase assembly factor:Uncharacterized protein, possibly involved in utilization of glycolate and propanediol:Uncharacterized conserved protein:Transcription:Posttranslational modification, protein turnover, chaperones:Oxidative phosphorylation:Glyoxylate and dicarboxylate metabolism:Porphyrin and chlorophyll metabolism:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:Two-component system:General function prediction only:Function unknown:Signal transduction mechanisms:GGDEF:glcD:cyoE_ctaB:CoxB:CtaD_CoxA:Poorly characterized:Metabolism:Cellular processes and signaling:Information storage and processing:Other:Signal transduction:Heme, porphyrin, and cobalamin:Biosynthesis of cofactors, prosthetic groups, and carriers:Other:Electron transport:Metabolism:Metabolism:Global:Energy metabolism:Signal Transduction:Environmental Information Processing:Metabolism of Cofactors and Vitamins:Energy Metabolism:Carbohydrate Metabolism" 306 "Energy production and conversion:Predicted sugar kinase:Predicted N6-adenine-specific DNA methylase:Histidinol dehydrogenase:Nicotinate-nucleotide pyrophosphorylase:Tryptophanyl-tRNA synthetase:tRNA delta(2)-isopentenylpyrophosphate transferase:Ribonuclease D:Gamma-glutamyltransferase:Superfamily II DNA and RNA helicases:Uncharacterized membrane-associated protein:tRNA nucleotidyltransferase/poly(A) polymerase:ABC-type amino acid transport system, permease component:Predicted ATPase or kinase:Predicted thioesterase:ABC-type multidrug transport system, permease component:Predicted ATP-dependent serine protease:Predicted GTPases:Transcriptional regulator:Uncharacterized conserved protein:Uncharacterized Fe-S protein:HrpA-like helicases:Adenosine deaminase:Transcriptional regulators:Transcriptional regulators:Predicted iron-dependent peroxidase:Predicted NADH:ubiquinone oxidoreductase, subunit RnfB:Methylase of polypeptide chain release factors:Uncharacterized protein conserved in bacteria:NhaP-type Na+/H+ and K+/H+ antiporters with a unique C-terminal domain:ABC-type transport system, involved in lipoprotein release, permease component:Membrane-bound metallopeptidase:Cell cycle control, cell division, chromosome partitioning:Amino acid transport and metabolism:Nucleotide transport and metabolism:Carbohydrate transport and metabolism:Coenzyme transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:Replication, recombination and repair:Cell wall/membrane/envelope biogenesis:Posttranslational modification, protein turnover, chaperones:Inorganic ion transport and metabolism:Purine metabolism:Histidine metabolism:Tryptophan metabolism:Taurine and hypotaurine metabolism:Selenocompound metabolism:Cyanoamino acid metabolism:Glutathione metabolism:Arachidonic acid metabolism:Nicotinate and nicotinamide metabolism:Aminoacyl-tRNA biosynthesis:Metabolic pathways:Biosynthesis of secondary metabolites:ABC transporters:General function prediction only:Function unknown:g_glut_trans:hisD:nadC:HI0065_YjeE:TIGR00157:miaA:yjeF_cterm:trpS:TIGR00276:sms:hemK_fam:rnd:Dyp_perox_fam:aden_deam:HEQRo_perm_3TM:rnfB:DEAH_box_HrpB:lolCE:pcaR_pcaU:Defense mechanisms:Protein fate:Translation factors:tRNA and rRNA base modification:tRNA aminoacylation:Protein synthesis:RNA processing:Transcription:DNA replication, recombination, and repair:DNA metabolism:DNA interactions:Regulatory functions:Electron transport:Energy metabolism:Metabolism:Metabolism:Global:Membrane Transport:Environmental Information Processing:Translation:Genetic Information Processing:Metabolism of Cofactors and Vitamins:Metabolism of Other Amino Acids:Amino Acid Metabolism:Nucleotide Metabolism:Enzymes of unknown specificity:Lipid Metabolism:General:Amino acid biosynthesis:Histidine family:Biosynthesis of cofactors, prosthetic groups, and carriers:Glutathione and analogs:Pyridine nucleotides:Information storage and processing:Cellular processes and signaling:Metabolism:Poorly characterized:Unknown function:Amino acids, peptides and amines:Transport and binding proteins:Protein modification and repair:Protein and peptide secretion and trafficking" 307 "Energy production and conversion:Serine/threonine protein kinase:Sugar kinases, ribokinase family:Transcriptional regulator:Mannose-6-phosphate isomerase:Outer membrane protein:NADH:ubiquinone oxidoreductase subunit 3 (chain A):ABC-type metal ion transport system, periplasmic component/surface antigen:Membrane transporters of cations and cationic drugs:Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain:AraC-type DNA-binding domain-containing proteins:Arabinose efflux permease:Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta):Carbohydrate transport and metabolism:Lipid transport and metabolism:Transcription:Replication, recombination and repair:Cell wall/membrane/envelope biogenesis:Inorganic ion transport and metabolism:Fructose and mannose metabolism:Oxidative phosphorylation:Starch and sucrose metabolism:Amino sugar and nucleotide sugar metabolism:Metabolic pathways:ABC transporters:General function prediction only:Signal transduction mechanisms:Metabolism:Poorly characterized:Metabolism:Cellular processes and signaling:Information storage and processing:Metabolism:Global:Membrane Transport:Environmental Information Processing:Energy Metabolism:Carbohydrate Metabolism" 308 "Phosphoribosylaminoimidazole carboxylase (NCAIR synthetase):Dimethyladenosine transferase (rRNA methylation):Phosphoribosylcarboxyaminoimidazole (NCAIR) mutase:Ribose 5-phosphate isomerase:AICAR transformylase/IMP cyclohydrolase PurH (only IMP cyclohydrolase domain in Aful):Phosphoribosylaminoimidazole (AIR) synthetase:Protein chain release factor A:Adenine/guanine phosphoribosyltransferases and related PRPP-binding proteins:Predicted Fe-S-cluster redox enzyme:S-adenosylmethionine decarboxylase:Factor for inversion stimulation Fis, transcriptional activator:Amino acid transport and metabolism:Nucleotide transport and metabolism:Carbohydrate transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:Replication, recombination and repair:Pentose phosphate pathway:Purine metabolism:Cysteine and methionine metabolism:Arginine and proline metabolism:One carbon pool by folate:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:Ribosome:General function prediction only:prfB:rpiA:TIGR00048:purH:ksgA:purM:rpmH_bact:purK:purE:XPRTase:SAM_DCase_Eco:Ribosomal proteins: synthesis and modification:Carbohydrate Metabolism:Nucleotide Metabolism:Amino Acid Metabolism:Metabolism of Cofactors and Vitamins:Genetic Information Processing:Translation:Global:Metabolism:Central intermediary metabolism:Polyamine biosynthesis:Energy metabolism:Pentose phosphate pathway:Purines, pyrimidines, nucleosides, and nucleotides:Purine ribonucleotide biosynthesis:Salvage of nucleosides and nucleotides:Protein synthesis:Metabolism:tRNA and rRNA base modification:Translation factors:Information storage and processing:Metabolism:Poorly characterized" 309 "Phosphoribosylanthranilate isomerase:Uncharacterized conserved protein:Glutamate dehydrogenase/leucine dehydrogenase:Mg2+ and Co2+ transporters:Uncharacterized enzymes related to aldose 1-epimerase:Predicted transcriptional regulators:Methyl-accepting chemotaxis protein:Cation/multidrug efflux pump:Membrane-fusion protein:Cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes:Co/Zn/Cd efflux system component:Transcriptional regulator:Outer membrane protein:Uncharacterized protein conserved in bacteria:Predicted transcriptional regulator:Transcriptional regulators:Predicted membrane protein:Sugar phosphate permease:Plasmid stabilization system protein:Predicted transcriptional regulator:Amino acid transport and metabolism:Carbohydrate transport and metabolism:Transcription:Cell wall/membrane/envelope biogenesis:Cell motility:Inorganic ion transport and metabolism:Alanine aspartate and glutamate metabolism:Arginine and proline metabolism:Phenylalanine tyrosine and tryptophan biosynthesis:Thiamine metabolism:Nitrogen metabolism:Metabolic pathways:Biosynthesis of secondary metabolites:Two-component system:Bacterial chemotaxis:Sulfur relay system:General function prediction only:Function unknown:Signal transduction mechanisms:TIGR00049:rrf2_super:CDF:RND_mfp:outer_NodT:SoxR:IscS:Intracellular trafficking, secretion, and vesicular transport:Defense mechanisms:General:Energy Metabolism:Amino Acid Metabolism:Metabolism of Cofactors and Vitamins:Genetic Information Processing:Folding Sorting and Degradation:Environmental Information Processing:Signal Transduction:Cellular Processes:Cell Motility:Global:Metabolism:Regulatory functions:DNA interactions:Protein synthesis:tRNA and rRNA base modification:Transport and binding proteins:Unknown substrate:Cations and iron carrying compounds:Porins:Unknown function:Metabolism:Biosynthesis of cofactors, prosthetic groups, and carriers:Other:Information storage and processing:Cellular processes and signaling:Metabolism:Poorly characterized" 310 "Chromatin structure and dynamics:Deacetylases, including yeast histone deacetylase and acetoin utilization protein:Glutamine synthetase:Na+-driven multidrug efflux pump:Glycine/D-amino acid oxidases (deaminating):Spermidine/putrescine-binding periplasmic protein:ABC-type spermidine/putrescine transport system, permease component II:Permeases:Sugar phosphate permease:Arabinose efflux permease:Hemolysin activation/secretion protein:Phospholipase C:Predicted flavin-nucleotide-binding protein structurally related to pyridoxine 5'-phosphate oxidase:Uncharacterized conserved protein:Amino acid transport and metabolism:Carbohydrate transport and metabolism:Cell wall/membrane/envelope biogenesis:Alanine aspartate and glutamate metabolism:Arginine and proline metabolism:Inositol phosphate metabolism:Glycerophospholipid metabolism:Ether lipid metabolism:Nitrogen metabolism:Metabolic pathways:Microbial metabolism in diverse environments:Two-component system:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:Function unknown:matE:PC_PLC:Intracellular trafficking, secretion, and vesicular transport:Defense mechanisms:Poorly characterized:Metabolism:Cellular processes and signaling:Information storage and processing:Pathogenesis:Cellular processes:Other:Transport and binding proteins:Metabolism:Global:Signal Transduction:Environmental Information Processing:Amino Acid Metabolism:Lipid Metabolism:Energy Metabolism:Metabolism:Carbohydrate Metabolism" 311 "Uncharacterized NAD(FAD)-dependent dehydrogenases:Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily):ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components:Predicted permeases:Pyruvate-formate lyase-activating enzyme:Acyl carrier protein phosphodiesterase:Predicted membrane protein:DNA repair photolyase:Ferredoxin subunits of nitrite reductase and ring-hydroxylating dioxygenases:Type II secretory pathway, pseudopilin PulG:AraC-type DNA-binding domain-containing proteins:Predicted membrane protein:Arabinose efflux permease:CBS-domain-containing membrane protein:Response regulator with putative antiterminator output domain:Type II secretory pathway, component PulJ:Carbohydrate transport and metabolism:Lipid transport and metabolism:Transcription:Replication, recombination and repair:Cell motility:Posttranslational modification, protein turnover, chaperones:Inorganic ion transport and metabolism:Nitrogen metabolism:Microbial metabolism in diverse environments:ABC transporters:Bacterial secretion system:General function prediction only:Function unknown:Signal transduction mechanisms:typeII_sec_gspH:nirD_assim_sml:NrdG2:IV_pilin_GFxxxE:Intracellular trafficking, secretion, and vesicular transport:Environmental Information Processing:Pathogenesis:Energy Metabolism:Information storage and processing:Cellular processes and signaling:Metabolism:Poorly characterized:Cellular processes:Metabolism:Protein modification and repair:Protein and peptide secretion and trafficking:Protein fate:Nitrogen metabolism:Central intermediary metabolism:Metabolism:Global:Membrane Transport" 312 "Energy production and conversion:Predicted translation initiation factor 2B subunit, eIF-2B alpha/beta/delta family:Mismatch repair ATPase (MutS family):3-oxoacyl-(acyl-carrier-protein) synthase:Dihydroorotase:Phosphopantothenoylcysteine synthetase/decarboxylase:Superfamily II DNA and RNA helicases:Heme/copper-type cytochrome/quinol oxidases, subunit 1:Predicted SAM-dependent methyltransferases:Threonine dehydratase:4-diphosphocytidyl-2-methyl-D-erithritol synthase:Heme/copper-type cytochrome/quinol oxidases, subunit 2:Heme/copper-type cytochrome/quinol oxidase, subunit 3:Predicted transporter component:Glycerol-3-phosphate O-acyltransferase:Heme/copper-type cytochrome/quinol oxidase, subunit 4:Amino acid transport and metabolism:Nucleotide transport and metabolism:Coenzyme transport and metabolism:Lipid transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:Replication, recombination and repair:Fatty acid biosynthesis:Oxidative phosphorylation:Pyrimidine metabolism:Glycine serine and threonine metabolism:Cysteine and methionine metabolism:Valine leucine and isoleucine biosynthesis:Glycerolipid metabolism:Glycerophospholipid metabolism:Pantothenate and CoA biosynthesis:Terpenoid backbone biosynthesis:Metabolic pathways:Biosynthesis of secondary metabolites:RNA degradation:Mismatch repair:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:ispD:salvage_mtnA:coaBC_dfp:pyrC_dimer:mutS1:ilvA_2Cterm:CyoA:CyoC:CyoB:CyoD:fabF:plsB:Other:Energy Metabolism:Lipid Metabolism:Nucleotide Metabolism:Amino Acid Metabolism:Metabolism of Cofactors and Vitamins:Metabolism of Terpenoids and Polyketides:Genetic Information Processing:Folding Sorting and Degradation:Replication and Repair:Global:Metabolism:Energy metabolism:Electron transport:Fatty acid and phospholipid metabolism:Biosynthesis:Purines, pyrimidines, nucleosides, and nucleotides:Pyrimidine ribonucleotide biosynthesis:DNA metabolism:DNA replication, recombination, and repair:Amino acid biosynthesis:Aspartate family:Pyruvate family:Biosynthesis of cofactors, prosthetic groups, and carriers:Metabolism:Pantothenate and coenzyme A:Information storage and processing:Metabolism:Poorly characterized" 313 "Energy production and conversion:Phosphoserine phosphatase:ABC-type antimicrobial peptide transport system, permease component:Predicted dehydrogenase:Transcriptional regulator:Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily):Predicted phosphatase/phosphohexomutase:Signal transduction histidine kinase:Outer membrane protein:Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain:Catalase:Predicted thioesterase:Membrane-fusion protein:Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases):ABC-type transport system involved in multi-copper enzyme maturation, permease component:Phosphotransferase system, fructose-specific IIC component:Amidases related to nicotinamidase:Predicted ATPase:Outer membrane protein:N-Dimethylarginine dimethylaminohydrolase:NADH:flavin oxidoreductases, Old Yellow Enzyme family:Site-specific recombinases, DNA invertase Pin homologs:Adenosine deaminase:Osmosensitive K+ channel histidine kinase:AraC-type DNA-binding domain-containing proteins:Predicted aminopeptidases:Uncharacterized protein conserved in bacteria:Predicted ATPase/kinase involved in NAD metabolism:Uncharacterized protein conserved in bacteria:Uncharacterized protein conserved in bacteria:Uncharacterized protein conserved in bacteria:Predicted transmembrane sensor domain:Amino acid transport and metabolism:Nucleotide transport and metabolism:Carbohydrate transport and metabolism:Coenzyme transport and metabolism:Lipid transport and metabolism:Transcription:Replication, recombination and repair:Cell wall/membrane/envelope biogenesis:Inorganic ion transport and metabolism:Fructose and mannose metabolism:Fatty acid biosynthesis:Tryptophan metabolism:Methane metabolism:Biosynthesis of unsaturated fatty acids:Metabolic pathways:Microbial metabolism in diverse environments:Two-component system:Phosphotransferase system (PTS):Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:Function unknown:Signal transduction mechanisms:ogt:FRU:autotrans_barl:HAD-SF-IB:HAD-SF-IA-v3:RND_mfp:TIGR02448:Intracellular trafficking, secretion, and vesicular transport:Defense mechanisms:Unknown function:Pathogenesis:Cellular processes:Unknown substrate:Transport and binding proteins:DNA replication, recombination, and repair:DNA metabolism:Metabolism:Global:Signal Transduction:Membrane Transport:Environmental Information Processing:Amino Acid Metabolism:Lipid Metabolism:Energy Metabolism:Carbohydrate Metabolism:Metabolism:Poorly characterized:Metabolism:Cellular processes and signaling:Information storage and processing:PTS:Signal transduction:Enzymes of unknown specificity" 314 "Queuine/archaeosine tRNA-ribosyltransferase:Spermidine synthase:2-methylthioadenine synthetase:Hypoxanthine-guanine phosphoribosyltransferase:Spermidine/putrescine-binding periplasmic protein:Na+/alanine symporter:ABC-type spermidine/putrescine transport system, permease component I:ABC-type spermidine/putrescine transport system, permease component II:Permeases:SAM-dependent methyltransferases related to tRNA (uracil-5-)-methyltransferase:Nucleoside-binding outer membrane protein:ABC-type spermidine/putrescine transport systems, ATPase components:Amino acid transport and metabolism:Nucleotide transport and metabolism:Translation, ribosomal structure and biogenesis:Cell wall/membrane/envelope biogenesis:Purine metabolism:Cysteine and methionine metabolism:Arginine and proline metabolism:beta-Alanine metabolism:Glutathione metabolism:Metabolic pathways:Biosynthesis of secondary metabolites:ABC transporters:General function prediction only:TIGR00089:speE:Q_tRNA_tgt:agcS:potA:trmA_only:Metabolism:Nucleotide Metabolism:Amino Acid Metabolism:Metabolism of Other Amino Acids:Environmental Information Processing:Membrane Transport:Global:Metabolism:Central intermediary metabolism:Polyamine biosynthesis:Protein synthesis:tRNA and rRNA base modification:Transport and binding proteins:Amino acids, peptides and amines:Information storage and processing:Cellular processes and signaling:Metabolism:Poorly characterized" 315 "Energy production and conversion:Predicted ATPase of the PP-loop superfamily implicated in cell cycle control:Glycine cleavage system T protein (aminomethyltransferase):Superfamily II DNA and RNA helicases:Na+/proline symporter:Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain:Methyl-accepting chemotaxis protein:Na+/alanine symporter:Predicted glycosyltransferases:Transcriptional regulators:3-methyladenine DNA glycosylase:Predicted membrane-associated, metal-dependent hydrolase:Predicted ATPase (AAA+ superfamily):Predicted hydrolase of the alpha/beta superfamily:ABC-type uncharacterized transport system, permease component:Delta 1-pyrroline-5-carboxylate dehydrogenase:Uncharacterized protein conserved in bacteria:Putative Mg2+ and Co2+ transporter CorB:Predicted secreted protein:Cell cycle control, cell division, chromosome partitioning:Amino acid transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:Replication, recombination and repair:Cell motility:Inorganic ion transport and metabolism:Alanine aspartate and glutamate metabolism:Glycine serine and threonine metabolism:Arginine and proline metabolism:One carbon pool by folate:Nitrogen metabolism:Metabolic pathways:Biosynthesis of secondary metabolites:Two-component system:Bacterial chemotaxis:Base excision repair:General function prediction only:Function unknown:Signal transduction mechanisms:gcvT:sss:agcS:D1pyr5carbox3:HpaR:lysidine_TilS_N:Cellular processes and signaling:Information storage and processing:Cations and iron carrying compounds:Transport and binding proteins:tRNA and rRNA base modification:Protein synthesis:Amino acids and amines:Energy metabolism:Metabolism:Metabolism:Global:Cell Motility:Cellular Processes:Signal Transduction:Environmental Information Processing:Replication and Repair:Genetic Information Processing:Metabolism of Cofactors and Vitamins:Amino Acid Metabolism:Poorly characterized:Energy Metabolism:Metabolism" 316 "Energy production and conversion:Signal transduction histidine kinase:Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains):Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain:Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes:Transcriptional regulator:Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor):Uncharacterized conserved protein:Uncharacterized protein SCO1/SenC/PrrC, involved in biogenesis of respiratory and photosynthetic systems:Uncharacterized protein conserved in bacteria:Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain:Uncharacterized enzyme of heme biosynthesis:Uncharacterized protein conserved in bacteria:Uncharacterized protein conserved in bacteria:Predicted periplasmic protein:Coenzyme transport and metabolism:Transcription:Cell wall/membrane/envelope biogenesis:Nicotinate and nicotinamide metabolism:Metabolic pathways:General function prediction only:Function unknown:Signal transduction mechanisms:Poorly characterized:Metabolism:Cellular processes and signaling:Information storage and processing:Metabolism:Global:Metabolism of Cofactors and Vitamins:Metabolism" 317 "Energy production and conversion:2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway):Molybdopterin biosynthesis enzyme:Molybdopterin biosynthesis enzymes:Parvulin-like peptidyl-prolyl isomerase:NAD-dependent aldehyde dehydrogenases:Nitrate reductase beta subunit:Nitrate reductase delta subunit:Nitrate reductase gamma subunit:AraC-type DNA-binding domain-containing proteins:Nitrate/nitrite transporter:Sugar phosphate permease:Molybdenum cofactor biosynthesis enzyme:5-carboxymethyl-2-hydroxymuconate isomerase:Uncharacterized conserved protein:2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase:2-keto-4-pentenoate hydratase:Nitrate reductase alpha subunit:Amino acid transport and metabolism:Carbohydrate transport and metabolism:Coenzyme transport and metabolism:Transcription:Posttranslational modification, protein turnover, chaperones:Inorganic ion transport and metabolism:Tyrosine metabolism:Benzoate degradation:Nitrogen metabolism:Microbial metabolism in diverse environments:Two-component system:Sulfur relay system:Secondary metabolites biosynthesis, transport and catabolism:Function unknown:molyb_syn:narI:narJ:2A0108:narG:narH:HpaA:HpaD_Fe:HpaE:HpaG-C-term:HpaG-N-term:HpaI:HpaH:moaA:Information storage and processing:Molybdopterin:Biosynthesis of cofactors, prosthetic groups, and carriers:Anions:Transport and binding proteins:Protein folding and stabilization:Protein fate:Anaerobic:Energy metabolism:Metabolism:Metabolism:Global:Signal Transduction:Environmental Information Processing:Folding Sorting and Degradation:Genetic Information Processing:Xenobiotics Biodegradation and Metabolism:Amino Acid Metabolism:Poorly characterized:Energy Metabolism:Metabolism:Cellular processes and signaling" 318 "Glucan phosphorylase:1,4-alpha-glucan branching enzyme:Glycogen synthase:FOG: CBS domain:Putative intracellular protease/amidase:Catalase:Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases):Threonine dehydrogenase and related Zn-dependent dehydrogenases:Cellulase M and related proteins:Type II secretory pathway, pullulanase PulA and related glycosidases:4-alpha-glucanotransferase:Maltooligosyl trehalose synthase:Metal-dependent hydrolase:Amino acid transport and metabolism:Carbohydrate transport and metabolism:Lipid transport and metabolism:Inorganic ion transport and metabolism:Tryptophan metabolism:Starch and sucrose metabolism:Methane metabolism:Metabolic pathways:Microbial metabolism in diverse environments:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:malQ:PfpI:branching_enzym:P_ylase:glgA:glgX_debranch:trehalose_TreY:trehalose_TreZ:Metabolism:Degradation of proteins, peptides, and glycopeptides:Protein fate:Biosynthesis and degradation of polysaccharides:Energy metabolism:Metabolism:Metabolism:Global:Amino Acid Metabolism:Energy Metabolism:Poorly characterized:Carbohydrate Metabolism" 319 "Energy production and conversion:Acetyl-CoA acetyltransferase:Signal transduction histidine kinase:Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain:Enoyl-CoA hydratase/carnithine racemase:Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases):Acyl-CoA synthetase (NDP forming):Transcriptional regulator:Beta-lactamase class C and other penicillin binding proteins:Acyl-CoA dehydrogenases:Acyl dehydratase:K+-transporting ATPase, A chain:Dioxygenases related to 2-nitropropane dioxygenase:High-affinity K+ transport system, ATPase chain B:Predicted membrane protein:Uncharacterized protein conserved in bacteria:Uncharacterized protein conserved in bacteria:Uncharacterized low-complexity protein:Lipid transport and metabolism:Transcription:Inorganic ion transport and metabolism:Fatty acid metabolism:Valine leucine and isoleucine degradation:Geraniol degradation:Lysine degradation:Penicillin and cephalosporin biosynthesis:Benzoate degradation:Tryptophan metabolism:beta-Alanine metabolism:Naphthalene degradation:Aminobenzoate degradation:Propanoate metabolism:Butanoate metabolism:Limonene and pinene degradation:Nitrogen metabolism:Caprolactam degradation:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:Two-component system:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:Function unknown:Signal transduction mechanisms:kdpA:ATPase_P-type:potass_kdpF:Defense mechanisms:Metabolism:Cellular processes and signaling:Information storage and processing:Cations and iron carrying compounds:Transport and binding proteins:Metabolism:Metabolism:Global:Signal Transduction:Environmental Information Processing:Xenobiotics Biodegradation and Metabolism:Biosynthesis of Other Secondary Metabolites:Metabolism of Terpenoids and Polyketides:Metabolism of Other Amino Acids:Amino Acid Metabolism:Lipid Metabolism:Energy Metabolism:Carbohydrate Metabolism:Poorly characterized" 320 "Energy production and conversion:Membrane protease subunits, stomatin/prohibitin homologs:Predicted hydrolase of the alpha/beta-hydrolase fold:Glycerol kinase:Phosphoserine phosphatase:Transcriptional regulator:Uncharacterized homolog of gamma-carboxymuconolactone decarboxylase subunit:Predicted oxidoreductases (related to aryl-alcohol dehydrogenases):Predicted nucleoside-diphosphate-sugar epimerases:Putative heme iron utilization protein:Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases):Threonine dehydratase:Transcriptional regulators:GAF domain-containing protein:3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases:Adenosine deaminase:FOG: PAS/PAC domain:Predicted Zn-dependent hydrolases of the beta-lactamase fold:Lysophospholipase:Transposase and inactivated derivatives:Uncharacterized protein involved in benzoate metabolism:Transposase and inactivated derivatives:Predicted methylated DNA-protein cysteine methyltransferase:ABC-type spermidine/putrescine transport systems, ATPase components:Predicted protein tyrosine phosphatase:Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain:Predicted periplasmic lipoprotein:Amino acid transport and metabolism:Nucleotide transport and metabolism:Carbohydrate transport and metabolism:Lipid transport and metabolism:Transcription:Replication, recombination and repair:Cell wall/membrane/envelope biogenesis:Posttranslational modification, protein turnover, chaperones:Inorganic ion transport and metabolism:Fructose and mannose metabolism:Glycine serine and threonine metabolism:Valine leucine and isoleucine biosynthesis:Benzoate degradation:Bisphenol degradation:Glycerolipid metabolism:Chloroalkane and chloroalkene degradation:Butanoate metabolism:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:Two-component system:Bacterial chemotaxis:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:Function unknown:Signal transduction mechanisms:sensory_box:benE:HAD-SF-IB:Poorly characterized:Carbohydrate Metabolism:Metabolism:Cellular processes and signaling:Information storage and processing:Enzymes of unknown specificity:Unknown function:Carbohydrates, organic alcohols, and acids:Transport and binding proteins:Small molecule interactions:Regulatory functions:Metabolism:Metabolism:Global:Cell Motility:Cellular Processes:Signal Transduction:Environmental Information Processing:Xenobiotics Biodegradation and Metabolism:Amino Acid Metabolism:Lipid Metabolism" 321 "Predicted epimerase, PhzC/PhzF homolog:DNA polymerase elongation subunit (family B):Glycerol uptake facilitator and related permeases (Major Intrinsic Protein Family):Transcriptional regulator:Predicted Zn-dependent peptidases:Signal transduction histidine kinase:Permeases of the drug/metabolite transporter (DMT) superfamily:Membrane proteins related to metalloendopeptidases:FOG: TPR repeat, SEL1 subfamily:Predicted thioesterase:Predicted hydrolase (HAD superfamily):Predicted SAM-dependent methyltransferases:3'-Phosphoadenosine 5'-phosphosulfate (PAPS) 3'-phosphatase:Predicted membrane protein:Predicted transcriptional regulator containing the HTH domain:Predicted transcriptional regulators:DNA uptake protein and related DNA-binding proteins:Multidrug resistance efflux pump:Allophanate hydrolase subunit 1:AraC-type DNA-binding domain-containing proteins:Uncharacterized protein involved in benzoate metabolism:Predicted protein tyrosine phosphatase:Uncharacterized protein conserved in bacteria:Flp pilus assembly protein, protease CpaA:Amino acid transport and metabolism:Carbohydrate transport and metabolism:Transcription:Replication, recombination and repair:Cell wall/membrane/envelope biogenesis:Posttranslational modification, protein turnover, chaperones:Inorganic ion transport and metabolism:Aminoacyl-tRNA biosynthesis:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:Function unknown:Signal transduction mechanisms:TIGR00281:TIGR00370:TIGR00426:PhzF_family:benE:MIP:bisphos_cysQ:HAD-SF-IA-v3:RND_mfp:Intracellular trafficking, secretion, and vesicular transport:Defense mechanisms:Toxin production and resistance:Cellular processes:Carbohydrates, organic alcohols, and acids:Unknown substrate:Transport and binding proteins:Chromosome-associated proteins:DNA metabolism:Sulfur metabolism:Central intermediary metabolism:Translation:Genetic Information Processing:Poorly characterized:Metabolism:Cellular processes and signaling:Information storage and processing:Enzymes of unknown specificity:Unknown function:Conserved:Hypothetical proteins:DNA transformation" 322 "Acetyl-CoA acetyltransferase:Glycosyltransferase:Putative intracellular protease/amidase:Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases):Predicted membrane protein:DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog:Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase:Predicted redox protein, regulator of disulfide bond formation:Formate/nitrite family of transporters:Uncharacterized conserved protein:Putative NADH-flavin reductase:Uncharacterized protein involved in outer membrane biogenesis:Poly(3-hydroxybutyrate) depolymerase:Lipid transport and metabolism:Transcription:Cell wall/membrane/envelope biogenesis:Posttranslational modification, protein turnover, chaperones:Inorganic ion transport and metabolism:Fatty acid biosynthesis:Fatty acid metabolism:Synthesis and degradation of ketone bodies:Valine leucine and isoleucine degradation:Lysine degradation:Benzoate degradation:Tryptophan metabolism:Pyruvate metabolism:Glyoxylate and dicarboxylate metabolism:Propanoate metabolism:Butanoate metabolism:Carbon fixation pathways in prokaryotes:Terpenoid backbone biosynthesis:Biosynthesis of unsaturated fatty acids:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:Two-component system:RNA polymerase:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:Function unknown:TIGR00147:yihY_not_rbn:PfpI:AcCoA-C-Actrans:sigma70-ECF:osmo_induc_OsmC:General:Information storage and processing:Cellular processes and signaling:Metabolism:Poorly characterized:Unknown function:Detoxification:Metabolism:Global:Cellular processes:Degradation of proteins, peptides, and glycopeptides:Protein fate:Other:Signal Transduction:Environmental Information Processing:Fatty acid and phospholipid metabolism:Transcription:Genetic Information Processing:Xenobiotics Biodegradation and Metabolism:Metabolism:Metabolism of Terpenoids and Polyketides:Amino Acid Metabolism:Lipid Metabolism:Energy Metabolism:Enzymes of unknown specificity:Carbohydrate Metabolism" 323 "3-polyprenyl-4-hydroxybenzoate decarboxylase and related decarboxylases:Acetyltransferases:Transcriptional regulator:Enoyl-CoA hydratase/carnithine racemase:Acyl carrier protein phosphodiesterase:Alkyl sulfatase and related hydrolases:Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain:AraC-type DNA-binding domain-containing proteins:Predicted membrane protein:DNA-binding HTH domain-containing proteins:Transposase and inactivated derivatives:P pilus assembly protein, pilin FimA:Uncharacterized conserved protein:Phenylpropionate dioxygenase and related ring-hydroxylating dioxygenases, large terminal subunit:Signal transduction histidine kinase:Coenzyme transport and metabolism:Lipid transport and metabolism:Transcription:Replication, recombination and repair:Cell motility:Inorganic ion transport and metabolism:Fatty acid metabolism:Valine leucine and isoleucine degradation:Geraniol degradation:Lysine degradation:Benzoate degradation:Tryptophan metabolism:beta-Alanine metabolism:Aminobenzoate degradation:Propanoate metabolism:Butanoate metabolism:Limonene and pinene degradation:Caprolactam degradation:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:Two-component system:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:Function unknown:Signal transduction mechanisms:TIGR00148:reg_near_HchA:Intracellular trafficking, secretion, and vesicular transport:General:Metabolism of Terpenoids and Polyketides:Unknown function:Metabolism of Other Amino Acids:Amino Acid Metabolism:Lipid Metabolism:Poorly characterized:Carbohydrate Metabolism:Metabolism:Global:Signal Transduction:Environmental Information Processing:Metabolism:Cellular processes and signaling:Information storage and processing:Xenobiotics Biodegradation and Metabolism:Metabolism" 324 "ABC-type phosphate transport system, periplasmic component:Glycosyltransferase:FOG: CBS domain:Transcriptional regulator:Predicted permeases:FOG: TPR repeat, SEL1 subfamily:Threonine dehydrogenase and related Zn-dependent dehydrogenases:ABC-type spermidine/putrescine transport system, permease component I:ABC-type spermidine/putrescine transport system, permease component II:Predicted glycosyltransferases:Amidases related to nicotinamidase:Arabinose efflux permease:Predicted membrane protein:Transposase and inactivated derivatives:Uncharacterized protein conserved in bacteria:Predicted signal transduction protein containing sensor and EAL domains:Amino acid transport and metabolism:Carbohydrate transport and metabolism:Transcription:Replication, recombination and repair:Cell wall/membrane/envelope biogenesis:Inorganic ion transport and metabolism:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:Function unknown:Signal transduction mechanisms:Poorly characterized:Metabolism:Cellular processes and signaling:Information storage and processing" 325 "Energy production and conversion:ABC-type Fe3+-siderophore transport system, permease component:ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components:DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog:Outer membrane receptor proteins, mostly Fe transport:Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases:Bacterioferritin-associated ferredoxin:Fe2+-dicitrate sensor, membrane component:ABC-type Fe2+-enterobactin transport system, periplasmic component:ABC-type enterobactin transport system, permease component:Coenzyme transport and metabolism:Transcription:Inorganic ion transport and metabolism:ABC transporters:RNA polymerase:Signal transduction mechanisms:sigma70-ECF:FMN_nitrolo:Membrane Transport:Environmental Information Processing:Metabolism:Transcription:Genetic Information Processing:Cellular processes and signaling:Information storage and processing:Enzymes of unknown specificity:Unknown function" 326 "Energy production and conversion:tRNA-dihydrouridine synthase:Tyrosyl-tRNA synthetase:Thioredoxin reductase:Transcriptional regulator:Predicted oxidoreductases (related to aryl-alcohol dehydrogenases):Predicted permeases:Glycosyltransferases, probably involved in cell wall biogenesis:Uncharacterized conserved protein:Probable taurine catabolism dioxygenase:Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain:Predicted transcriptional regulator:Arabinose efflux permease:Phosphopantetheinyl transferase component of siderophore synthetase:P pilus assembly protein, chaperone PapD:Uncharacterized protein conserved in bacteria:Uncharacterized protein conserved in bacteria:Predicted transcriptional regulator:Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain:Carbohydrate transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:Cell wall/membrane/envelope biogenesis:Cell motility:Posttranslational modification, protein turnover, chaperones:Aminoacyl-tRNA biosynthesis:Two-component system:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:Function unknown:Signal transduction mechanisms:tyrS:yjbN:ribofla_fusion:Intracellular trafficking, secretion, and vesicular transport:tRNA aminoacylation:Poorly characterized:Cellular processes and signaling:Information storage and processing:tRNA and rRNA base modification:Metabolism:Protein synthesis:Signal Transduction:Environmental Information Processing:Translation:Genetic Information Processing" 327 "Energy production and conversion:Putative translation initiation inhibitor, yjgF family:Glutaredoxin-related protein:S-adenosylhomocysteine hydrolase:cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases:Glycine/D-amino acid oxidases (deaminating):Bacterial nucleoid DNA-binding protein:NAD-dependent aldehyde dehydrogenases:Cold shock proteins:Transcriptional regulator:ABC-type metal ion transport system, periplasmic component/surface antigen:Protein-disulfide isomerase:Uncharacterized protein conserved in bacteria:Sec-independent protein secretion pathway components:Uncharacterized host factor I protein:Bacterioferritin (cytochrome b1):Cytochrome c553:Cytochrome c5:Uncharacterized protein conserved in bacteria:Amino acid transport and metabolism:Coenzyme transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:Replication, recombination and repair:Posttranslational modification, protein turnover, chaperones:Inorganic ion transport and metabolism:Purine metabolism:Glycine serine and threonine metabolism:Cysteine and methionine metabolism:Phenylalanine metabolism:Selenocompound metabolism:Nitrogen metabolism:Metabolic pathways:ABC transporters:RNA degradation:Protein export:Bacterial secretion system:General function prediction only:Function unknown:Signal transduction mechanisms:TIGR00052:TIGR00363:TIGR00365:bfr:ahcY:tatAE:BADH:Hfq:betaine_BetI:Intracellular trafficking, secretion, and vesicular transport:Poorly characterized:Energy Metabolism:Nucleotide Metabolism:Amino Acid Metabolism:Metabolism of Other Amino Acids:Genetic Information Processing:Folding Sorting and Degradation:Environmental Information Processing:Membrane Transport:Global:Metabolism:Energy metabolism:Amino acids and amines:Electron transport:Regulatory functions:Other:DNA interactions:Protein fate:Protein and peptide secretion and trafficking:Transport and binding proteins:Cations and iron carrying compounds:Cellular processes:Adaptations to atypical conditions:Unknown function:Enzymes of unknown specificity:Cell envelope:Other:Information storage and processing:Cellular processes and signaling:Metabolism:Metabolism" 328 "Energy production and conversion:Lactoylglutathione lyase and related lyases:Asparagine synthase (glutamine-hydrolyzing):Cytosine deaminase and related metal-dependent hydrolases:Acetyl-CoA hydrolase:Signal transduction histidine kinase:D-alanine-D-alanine ligase and related ATP-grasp enzymes:Lhr-like helicases:Na+/phosphate symporter:Cellulase M and related proteins:Uncharacterized protein conserved in bacteria:Transcriptional regulators:Ureidoglycolate hydrolase:Uncharacterized protein conserved in bacteria:Predicted NAD/FAD-dependent oxidoreductase:Predicted membrane protein:Uncharacterized protein conserved in bacteria:Uncharacterized protein conserved in bacteria:Allantoicase:Amino acid transport and metabolism:Nucleotide transport and metabolism:Carbohydrate transport and metabolism:Transcription:Cell wall/membrane/envelope biogenesis:Inorganic ion transport and metabolism:Purine metabolism:Alanine aspartate and glutamate metabolism:Pyruvate metabolism:Nitrogen metabolism:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:General function prediction only:Function unknown:Signal transduction mechanisms:glyox_I:sensory_box:NaPi_cotrn_rel:asn_synth_AEB:his_ut_repres:hutF:allantoicase:trio_acet_GNAT:trio_M42_hydro:UHCUDC:plc_access_R:Small molecule interactions:DNA interactions:Regulatory functions:Other:Amino acids and amines:Energy metabolism:Metabolism:Metabolism:Global:Amino Acid Metabolism:Nucleotide Metabolism:Energy Metabolism:Poorly characterized:Carbohydrate Metabolism:Metabolism:Cellular processes and signaling:Information storage and processing:Aspartate family:Amino acid biosynthesis:Cations and iron carrying compounds:Transport and binding proteins" 329 "Energy production and conversion:Ribosomal protein L24:Ribosomal protein S14:DNA-directed RNA polymerase, alpha subunit/40 kD subunit:Ribosomal protein L17:Ribosomal protein L29:Malic enzyme:Ketopantoate hydroxymethyltransferase:Panthothenate synthetase:Ribosomal protein S4 and related proteins:Aconitase B:Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily:Uncharacterized protein conserved in bacteria:FOG: WD40-like repeat:Phosphoserine aminotransferase:Uncharacterized protein conserved in bacteria:Tfp pilus assembly protein PilF:Uncharacterized conserved protein:Amino acid transport and metabolism:Coenzyme transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:Cell wall/membrane/envelope biogenesis:Cell motility:Citrate cycle (TCA cycle):Purine metabolism:Pyrimidine metabolism:Glycine serine and threonine metabolism:beta-Alanine metabolism:Pyruvate metabolism:Glyoxylate and dicarboxylate metabolism:Methane metabolism:Carbon fixation pathways in prokaryotes:Vitamin B6 metabolism:Pantothenate and CoA biosynthesis:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:Ribosome:RNA polymerase:Function unknown:L29:panC:L17:acnB:panB:rpsD_bact:rplX_bact:serC_1:rpoA:type_IV_pilW:assembly_YfgL:Intracellular trafficking, secretion, and vesicular transport:Metabolism:Poorly characterized:Energy metabolism:Metabolism:Global:Translation:Metabolism:Transcription:Genetic Information Processing:Metabolism of Cofactors and Vitamins:Metabolism of Other Amino Acids:Amino Acid Metabolism:Nucleotide Metabolism:Energy Metabolism:TCA cycle:Carbohydrate Metabolism:Transcription:DNA-dependent RNA polymerase:Protein synthesis:Ribosomal proteins: synthesis and modification:Protein fate:Protein and peptide secretion and trafficking:Amino acid biosynthesis:Serine family:Biosynthesis of cofactors, prosthetic groups, and carriers:Pantothenate and coenzyme A:Information storage and processing:Cellular processes and signaling" 330 "Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II:(acyl-carrier-protein) S-malonyltransferase:Cation transport ATPase:Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily):ABC-type amino acid transport system, permease component:Amino acid transporters:Enoyl-CoA hydratase/carnithine racemase:Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases):Na+/phosphate symporter:Acyl-CoA dehydrogenases:Multiple antibiotic transporter:Proline racemase:Predicted membrane protein:Inner membrane protein involved in colicin E2 resistance:Acetyl/propionyl-CoA carboxylase, alpha subunit:Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta):Predicted periplasmic lipoprotein:Amino acid transport and metabolism:Lipid transport and metabolism:Inorganic ion transport and metabolism:Fatty acid biosynthesis:Fatty acid metabolism:Valine leucine and isoleucine degradation:Geraniol degradation:beta-Alanine metabolism:Naphthalene degradation:Propanoate metabolism:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:ABC transporters:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:Function unknown:TIGR00427:malonate_madL:ATPase_P-type:HEQRo_perm_3TM:malonate_mdcH:malonate_gamma:Intracellular trafficking, secretion, and vesicular transport:Defense mechanisms:Poorly characterized:Metabolism:Cellular processes and signaling:General:Unknown function:Carbohydrates, organic alcohols, and acids:Amino acids, peptides and amines:Transport and binding proteins:Metabolism:Global:Membrane Transport:Environmental Information Processing:Xenobiotics Biodegradation and Metabolism:Metabolism of Terpenoids and Polyketides:Metabolism of Other Amino Acids:Amino Acid Metabolism:Lipid Metabolism:Metabolism:Carbohydrate Metabolism" 331 "Dihydroorotase and related cyclic amidohydrolases:Putative GTPases (G3E family):Carbonic anhydrases/acetyltransferases, isoleucine patch superfamily:Biopolymer transport proteins:N-acetylmuramoyl-L-alanine amidase:Cobalamin biosynthesis protein CobN and related Mg-chelatases:Uncharacterized conserved protein:Outer membrane receptor proteins, mostly Fe transport:DnaK suppressor protein:Predicted membrane protein:Uncharacterized protein conserved in bacteria:Uncharacterized conserved protein:Outer membrane receptor for ferrienterochelin and colicins:Nucleotide transport and metabolism:Coenzyme transport and metabolism:Cell wall/membrane/envelope biogenesis:Inorganic ion transport and metabolism:Pyrimidine metabolism:Porphyrin and chlorophyll metabolism:Metabolic pathways:General function prediction only:Function unknown:Signal transduction mechanisms:TonB-siderophor:dksA:Intracellular trafficking, secretion, and vesicular transport:Metabolism:Poorly characterized:Metabolism:Cellular processes and signaling:Porins:Transport and binding proteins:Small molecule interactions:Regulatory functions:Metabolism:Global:Metabolism of Cofactors and Vitamins:Nucleotide Metabolism" 332 "Energy production and conversion:Pentose-5-phosphate-3-epimerase:Aspartate-semialdehyde dehydrogenase:Glutamyl-tRNA reductase:4-hydroxybenzoate polyprenyltransferase and related prenyltransferases:Predicted phosphatases:Glutaredoxin and related proteins:Periplasmic protein TonB, links inner and outer membranes:Flavodoxin reductases (ferredoxin-NADPH reductases) family 1:Cold shock proteins:Transcriptional regulator:Uncharacterized stress-induced protein:Uncharacterized conserved protein:Predicted carbamoyl transferase, NodU family:Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains:Lysophospholipase:16S RNA G1207 methylase RsmC:4-hydroxybenzoate synthetase (chorismate lyase):Fatty acid desaturase:Amino acid transport and metabolism:Carbohydrate transport and metabolism:Coenzyme transport and metabolism:Lipid transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:Cell wall/membrane/envelope biogenesis:Posttranslational modification, protein turnover, chaperones:Pentose phosphate pathway:Pentose and glucuronate interconversions:Ubiquinone and other terpenoid-quinone biosynthesis:Glycine serine and threonine metabolism:Cysteine and methionine metabolism:Lysine biosynthesis:Glyoxylate and dicarboxylate metabolism:Porphyrin and chlorophyll metabolism:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:Two-component system:General function prediction only:Function unknown:Signal transduction mechanisms:tRNA_RlmH_YbeA:TIGR00255:hemA:rpe:tonB_Cterm:PGP_bact:ubiA_proteo:GRX_bact:Conserved:Carbohydrate Metabolism:Amino Acid Metabolism:Metabolism of Cofactors and Vitamins:Environmental Information Processing:Signal Transduction:Global:Metabolism:Energy metabolism:Electron transport:Pentose phosphate pathway:Sugars:Protein synthesis:tRNA and rRNA base modification:Transport and binding proteins:Cations and iron carrying compounds:Hypothetical proteins:Metabolism:Biosynthesis of cofactors, prosthetic groups, and carriers:Heme, porphyrin, and cobalamin:Menaquinone and ubiquinone:Information storage and processing:Cellular processes and signaling:Metabolism:Poorly characterized" 333 "Energy production and conversion:Shikimate 5-dehydrogenase:Phosphate/sulphate permeases:Zn-dependent hydrolases, including glyoxylases:FKBP-type peptidyl-prolyl cis-trans isomerases 1:Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily):NADPH:quinone reductase and related Zn-dependent oxidoreductases:Sulfate permease and related transporters (MFS superfamily):Collagenase and related proteases:Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases):3-hydroxyacyl-CoA dehydrogenase:Putative threonine efflux protein:Oxygen-sensitive ribonucleoside-triphosphate reductase:Uncharacterized ABC-type transport system, periplasmic component/surface lipoprotein:NADH:flavin oxidoreductases, Old Yellow Enzyme family:Adenosine deaminase:AraC-type DNA-binding domain-containing proteins:Putative lipid carrier protein:CBS-domain-containing membrane protein:Nucleoside 2-deoxyribosyltransferase:Uncharacterized conserved small protein:Amino acid transport and metabolism:Nucleotide transport and metabolism:Lipid transport and metabolism:Transcription:Posttranslational modification, protein turnover, chaperones:Inorganic ion transport and metabolism:Purine metabolism:Pyrimidine metabolism:Benzoate degradation:Phenylalanine tyrosine and tryptophan biosynthesis:Nitrotoluene degradation:Butanoate metabolism:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:Function unknown:Signal transduction mechanisms:aroE:sulP:NrdD:quinone_pig3:Anions:Transport and binding proteins:2'-Deoxyribonucleotide metabolism:Purines, pyrimidines, nucleosides, and nucleotides:Metabolism:Metabolism:Global:Xenobiotics Biodegradation and Metabolism:Amino Acid Metabolism:Nucleotide Metabolism:Carbohydrate Metabolism:Poorly characterized:Metabolism:Cellular processes and signaling:Information storage and processing:Aromatic amino acid family:Amino acid biosynthesis:Enzymes of unknown specificity:Unknown function" 334 "Energy production and conversion:Putative translation initiation inhibitor, yjgF family:Predicted amidohydrolase:Serine/threonine protein kinase:Sugar kinases, ribokinase family:Amino acid transporters:Transcriptional regulator:Glutathione S-transferase:Predicted amidophosphoribosyltransferases:Lactate dehydrogenase and related dehydrogenases:Predicted membrane protein:Metal-dependent amidase/aminoacylase/carboxypeptidase:Transcriptional regulators:Uncharacterized conserved protein:NADH:flavin oxidoreductases, Old Yellow Enzyme family:Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain:Cation transport ATPase:Sugar phosphate permease:DNA-binding HTH domain-containing proteins:Amino acid transport and metabolism:Carbohydrate transport and metabolism:Coenzyme transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:Replication, recombination and repair:Posttranslational modification, protein turnover, chaperones:Inorganic ion transport and metabolism:Pentose phosphate pathway:Phenylalanine metabolism:Glutathione metabolism:Metabolic pathways:Microbial metabolism in diverse environments:General function prediction only:Function unknown:Signal transduction mechanisms:ATPase_P-type:amidohydrolases:Cellular processes and signaling:Information storage and processing:Degradation of proteins, peptides, and glycopeptides:Protein fate:Metabolism:Global:Metabolism of Other Amino Acids:Amino Acid Metabolism:Metabolism:Carbohydrate Metabolism:Poorly characterized:Metabolism" 335 "Energy production and conversion:Polyprenyltransferase (cytochrome oxidase assembly factor):Predicted epimerase, PhzC/PhzF homolog:Uroporphyrinogen-III decarboxylase:Predicted redox protein, regulator of disulfide bond formation:ATPase components of ABC transporters with duplicated ATPase domains:Na+-driven multidrug efflux pump:Phosphoserine phosphatase:Transcriptional regulator:Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily):Predicted permease:Glycine/D-amino acid oxidases (deaminating):NAD-dependent aldehyde dehydrogenases:Predicted transcriptional regulators:Transcriptional regulator:Disulfide bond formation protein DsbB:Uncharacterized conserved protein:Uncharacterized protein, possibly involved in aromatic compounds catabolism:Cytochrome P450:Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain:AraC-type DNA-binding domain-containing proteins:Sugar phosphate permease:Arabinose efflux permease:Uncharacterized conserved protein:Uncharacterized protein conserved in bacteria:Predicted membrane protein:Uncharacterized protein conserved in bacteria:Uncharacterized protein conserved in bacteria:Amino acid transport and metabolism:Carbohydrate transport and metabolism:Coenzyme transport and metabolism:Transcription:Posttranslational modification, protein turnover, chaperones:Oxidative phosphorylation:Arginine and proline metabolism:Porphyrin and chlorophyll metabolism:Aminoacyl-tRNA biosynthesis:Metabolic pathways:Biosynthesis of secondary metabolites:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:Function unknown:Signal transduction mechanisms:unchar_dom_1:PhzF_family:TIGR00697:efflux_EmrB:matE:hemE:cyoE_ctaB:HAD-SF-IB:efp_adjacent_2:Defense mechanisms:Toxin production and resistance:Cellular processes:Other:Transport and binding proteins:Metabolism:Global:Translation:Genetic Information Processing:Metabolism of Cofactors and Vitamins:Amino Acid Metabolism:Energy Metabolism:Poorly characterized:Metabolism:Cellular processes and signaling:Metabolism:Information storage and processing:Heme, porphyrin, and cobalamin:Biosynthesis of cofactors, prosthetic groups, and carriers:Enzymes of unknown specificity:Unknown function:Conserved:Hypothetical proteins" 336 "Energy production and conversion:L-asparaginase/archaeal Glu-tRNAGln amidotransferase subunit D:Gamma-glutamyltransferase:ABC-type branched-chain amino acid transport systems, ATPase component:ABC-type branched-chain amino acid transport systems, ATPase component:Glycosyltransferase:ATPase components of ABC transporters with duplicated ATPase domains:Amino acid transporters:ABC-type amino acid transport system, permease component:Mannose-1-phosphate guanylyltransferase:NAD-dependent aldehyde dehydrogenases:GDP-D-mannose dehydratase:ABC-type polar amino acid transport system, ATPase component:ABC-type polysaccharide/polyol phosphate export systems, permease component:ABC-type branched-chain amino acid transport system, permease component:Ethanolamine ammonia-lyase, small subunit:Ethanolamine ammonia-lyase, large subunit:Amino acid transport and metabolism:Carbohydrate transport and metabolism:Translation, ribosomal structure and biogenesis:Cell wall/membrane/envelope biogenesis:Glycolysis / Gluconeogenesis:Pentose and glucuronate interconversions:Fructose and mannose metabolism:Ascorbate and aldarate metabolism:Fatty acid metabolism:Alanine aspartate and glutamate metabolism:Valine leucine and isoleucine degradation:Lysine degradation:Arginine and proline metabolism:Histidine metabolism:Tryptophan metabolism:beta-Alanine metabolism:Taurine and hypotaurine metabolism:Selenocompound metabolism:Cyanoamino acid metabolism:D-Glutamine and D-glutamate metabolism:Glutathione metabolism:Amino sugar and nucleotide sugar metabolism:Glycerolipid metabolism:Glycerophospholipid metabolism:Arachidonic acid metabolism:Pyruvate metabolism:Chloroalkane and chloroalkene degradation:Propanoate metabolism:Limonene and pinene degradation:Nitrogen metabolism:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:ABC transporters:General function prediction only:g_glut_trans:asnASE_II:2A0305:gmd:GMP_PMI:HEQRo_perm_3TM:Metabolism:Poorly characterized:Cellular processes and signaling:Information storage and processing:Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides:Cell envelope:Glutathione and analogs:Biosynthesis of cofactors, prosthetic groups, and carriers:Amino acids, peptides and amines:Transport and binding proteins:Amino acids and amines:Metabolism:Global:Energy metabolism:Membrane Transport:Environmental Information Processing:Xenobiotics Biodegradation and Metabolism:Metabolism of Terpenoids and Polyketides:Metabolism of Other Amino Acids:Amino Acid Metabolism:Lipid Metabolism:Metabolism:Energy Metabolism:Carbohydrate Metabolism" 337 "NhaP-type Na+/H+ and K+/H+ antiporters:Ni2+-binding GTPase involved in regulation of expression and maturation of urease and hydrogenase:Predicted amidohydrolase:Amino acid transporters:Transcriptional regulator:Predicted transcriptional regulators:Signal transduction histidine kinase:ABC-type spermidine/putrescine transport system, permease component II:Nicotinic acid phosphoribosyltransferase:Uncharacterized conserved protein:Multidrug resistance efflux pump:Conserved protein/domain typically associated with flavoprotein oxygenases, DIM6/NTAB family:RNA:NAD 2'-phosphotransferase:Glycerate kinase:Probable taurine catabolism dioxygenase:AraC-type DNA-binding domain-containing proteins:Hydrogenase/urease accessory protein:H+/gluconate symporter and related permeases:Arabinose efflux permease:Fatty acid desaturase:Amino acid transport and metabolism:Carbohydrate transport and metabolism:Coenzyme transport and metabolism:Lipid transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:Posttranslational modification, protein turnover, chaperones:Inorganic ion transport and metabolism:Glycine serine and threonine metabolism:Tyrosine metabolism:Taurine and hypotaurine metabolism:Glycerolipid metabolism:Glyoxylate and dicarboxylate metabolism:Methane metabolism:Nicotinate and nicotinamide metabolism:Aminoacyl-tRNA biosynthesis:Metabolic pathways:Microbial metabolism in diverse environments:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:Function unknown:Signal transduction mechanisms:TIGR00045:ureG:a_cpa1:2A0106:NAPRTase:fil_hemag_20aa:HpaC:Defense mechanisms:Information storage and processing:Carbohydrate Metabolism:Energy Metabolism:Lipid Metabolism:Amino Acid Metabolism:Metabolism of Other Amino Acids:Metabolism of Cofactors and Vitamins:Genetic Information Processing:Translation:Global:Metabolism:Central intermediary metabolism:Nitrogen metabolism:Energy metabolism:Other:Transport and binding proteins:Unknown substrate:Cations and iron carrying compounds:Biosynthesis of cofactors, prosthetic groups, and carriers:Pyridine nucleotides:Metabolism:Cellular processes and signaling:Metabolism:Poorly characterized" 338 "Energy production and conversion:Predicted aminomethyltransferase related to GcvT:Predicted flavoprotein:Predicted ATPase:Isocitrate/isopropylmalate dehydrogenase:Amino acid transporters:Transcriptional regulator:Glutathione S-transferase:Spermidine/putrescine-binding periplasmic protein:ABC-type transport system involved in resistance to organic solvents, permease component:ABC-type amino acid transport/signal transduction systems, periplasmic component/domain:ABC-type transport system involved in resistance to organic solvents, ATPase component:ABC-type antimicrobial peptide transport system, ATPase component:Putative threonine efflux protein:Transcriptional regulator:Transcriptional regulators:Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL homologs:Predicted redox protein, regulator of disulfide bond formation:Rubredoxin:Predicted membrane protein:Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS/CutS homologs:Membrane-bound lytic murein transglycosylase B:Transposase and inactivated derivatives:Uncharacterized protein conserved in bacteria:Predicted restriction endonuclease:Transcriptional regulator of aromatic amino acids metabolism:Predicted enzyme of the cupin superfamily:Uncharacterized protein conserved in bacteria:ABC-type spermidine/putrescine transport systems, ATPase components:Amino acid transport and metabolism:Transcription:Replication, recombination and repair:Cell wall/membrane/envelope biogenesis:Posttranslational modification, protein turnover, chaperones:Fatty acid metabolism:Valine leucine and isoleucine biosynthesis:Phenylalanine tyrosine and tryptophan biosynthesis:Glutathione metabolism:Metabolic pathways:Biosynthesis of secondary metabolites:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:Function unknown:Signal transduction mechanisms:TIGR00056:leuB:TIGR00701:potA:TAT_signal_seq:MltB:ygfZ_signature:Defense mechanisms:Metabolism:Poorly characterized:Metabolism:Cellular processes and signaling:Information storage and processing:Biosynthesis and degradation of murein sacculus and peptidoglycan:Cell envelope:Pyruvate family:Amino acid biosynthesis:Conserved:Hypothetical proteins:Amino acids, peptides and amines:Transport and binding proteins:Protein and peptide secretion and trafficking:Protein fate:tRNA and rRNA base modification:Protein synthesis:Metabolism:Global:Metabolism of Other Amino Acids:Amino Acid Metabolism:Lipid Metabolism" 339 "Energy production and conversion:ABC-type Fe3+-siderophore transport system, permease component:Signal transduction histidine kinase:Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain:DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog:Outer membrane receptor proteins, mostly Fe transport:Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases:Ferredoxin subunits of nitrite reductase and ring-hydroxylating dioxygenases:Bacterioferritin-associated ferredoxin:Uncharacterized iron-regulated protein:Fe2+-dicitrate sensor, membrane component:Putative heme degradation protein:ABC-type hemin transport system, periplasmic component:ABC-type hemin transport system, ATPase component:Outer membrane receptor for ferrienterochelin and colicins:Outer membrane receptor for ferric coprogen and ferric-rhodotorulic acid:Transcription:Inorganic ion transport and metabolism:ABC transporters:RNA polymerase:General function prediction only:Function unknown:Signal transduction mechanisms:TonB-siderophor:TonB-hemin:sigma70-ECF:FMN_nitrolo:Information storage and processing:Enzymes of unknown specificity:Unknown function:Porins:Transport and binding proteins:Membrane Transport:Environmental Information Processing:Genetic Information Processing:Transcription:Poorly characterized:Metabolism:Cellular processes and signaling" 340 "Energy production and conversion:Putative translation initiation inhibitor, yjgF family:Transcriptional regulator:Na+/proline symporter:NAD-dependent aldehyde dehydrogenases:Predicted membrane protein:TRAP-type C4-dicarboxylate transport system, large permease component:ABC-type proline/glycine betaine transport systems, periplasmic components:AraC-type DNA-binding domain-containing proteins:Sugar phosphate permease:DNA-binding HTH domain-containing proteins:Arabinose efflux permease:Arylsulfatase A and related enzymes:Gluconolactonase:Predicted amino acid aldolase or racemase:Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain:Amino acid transport and metabolism:Carbohydrate transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:Inorganic ion transport and metabolism:ABC transporters:Two-component system:General function prediction only:Function unknown:dctM:ABC_choline_bnd:chol_sulfatase:Membrane Transport:Environmental Information Processing:Poorly characterized:Metabolism:Information storage and processing:Carbohydrates, organic alcohols, and acids:Amino acids, peptides and amines:Transport and binding proteins:Signal Transduction" 341 "1-acyl-sn-glycerol-3-phosphate acyltransferase:Dihydropteroate synthase and related enzymes:Predicted Zn-dependent peptidases:Membrane proteins related to metalloendopeptidases:Phosphomannomutase:Arginine decarboxylase (spermidine biosynthesis):Phosphatidylserine synthase:Holliday junction resolvasome, helicase subunit:Surface lipoprotein:ABC-type transport system involved in resistance to organic solvents, auxiliary component:Membrane-bound lytic murein transglycosylase B:Uncharacterized protein conserved in bacteria:Predicted NTP binding protein (contains STAS domain):Uncharacterized protein conserved in bacteria:Amino acid transport and metabolism:Carbohydrate transport and metabolism:Coenzyme transport and metabolism:Lipid transport and metabolism:Replication, recombination and repair:Cell wall/membrane/envelope biogenesis:Purine metabolism:Pyrimidine metabolism:Glycine serine and threonine metabolism:Arginine and proline metabolism:Amino sugar and nucleotide sugar metabolism:Glycerolipid metabolism:Glycerophospholipid metabolism:Folate biosynthesis:Metabolic pathways:Homologous recombination:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:Function unknown:mazG:pssA:ruvB:speA:tonB_Cterm:glmM:DHPS:MltB:Cell envelope:Biosynthesis and degradation of murein sacculus and peptidoglycan:Information storage and processing:Cellular processes and signaling:Metabolism:Poorly characterized:Amino sugars:Central intermediary metabolism:Metabolism:Global:Metabolism:Replication and Repair:Genetic Information Processing:Metabolism of Cofactors and Vitamins:Amino Acid Metabolism:Nucleotide Metabolism:Lipid Metabolism:Polyamine biosynthesis:Carbohydrate Metabolism:Fatty acid and phospholipid metabolism:Biosynthesis:DNA metabolism:DNA replication, recombination, and repair:Transport and binding proteins:Cations and iron carrying compounds:Unknown function:General:Biosynthesis of cofactors, prosthetic groups, and carriers:Folic acid" 342 "Energy production and conversion:Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase]:Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases:Acetyl-CoA acetyltransferase:Dehydrogenases (flavoproteins):Demethylmenaquinone methyltransferase:Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain:3-hydroxyacyl-CoA dehydrogenase:NAD/NADP transhydrogenase beta subunit:Uncharacterized flagellar protein FlaG:Flagellin and related hook-associated proteins:Flagellar capping protein:Flagellin-specific chaperone FliS:Acyl-CoA dehydrogenases:Electron transfer flavoprotein, alpha subunit:Electron transfer flavoprotein, beta subunit:Uncharacterized conserved protein:Isocitrate lyase:Malate synthase:Putative sterol carrier protein:NAD/NADP transhydrogenase alpha subunit:P pilus assembly/Cpx signaling pathway, periplasmic inhibitor/zinc-resistance associated protein:Amino acid transport and metabolism:Coenzyme transport and metabolism:Lipid transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:Cell motility:Posttranslational modification, protein turnover, chaperones:Inorganic ion transport and metabolism:Fatty acid metabolism:Synthesis and degradation of ketone bodies:Valine leucine and isoleucine degradation:Geraniol degradation:Valine leucine and isoleucine biosynthesis:Lysine degradation:Arginine and proline metabolism:Phenylalanine metabolism:Benzoate degradation:Tryptophan metabolism:beta-Alanine metabolism:Cyanoamino acid metabolism:alpha-Linolenic acid metabolism:Pyruvate metabolism:Naphthalene degradation:Aminobenzoate degradation:Glyoxylate and dicarboxylate metabolism:Propanoate metabolism:Styrene degradation:Butanoate metabolism:C5-Branched dibasic acid metabolism:Carbon fixation pathways in prokaryotes:Nicotinate and nicotinamide metabolism:Pantothenate and CoA biosynthesis:Terpenoid backbone biosynthesis:Limonene and pinene degradation:Caprolactam degradation:Biosynthesis of unsaturated fatty acids:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:Two-component system:Flagellar assembly:Function unknown:Signal transduction mechanisms:fliS:malate_syn_G:AcCoA-C-Actrans:NOT-MenG:FadB:Intracellular trafficking, secretion, and vesicular transport:General:Carbohydrate Metabolism:Energy Metabolism:Lipid Metabolism:Amino Acid Metabolism:Metabolism of Other Amino Acids:Metabolism of Cofactors and Vitamins:Metabolism of Terpenoids and Polyketides:Xenobiotics Biodegradation and Metabolism:Environmental Information Processing:Signal Transduction:Cellular Processes:Cell Motility:Global:Metabolism:Energy metabolism:TCA cycle:Fatty acid and phospholipid metabolism:Other:Degradation:Cellular processes:Chemotaxis and motility:Unknown function:Metabolism:Information storage and processing:Cellular processes and signaling:Metabolism:Poorly characterized" 343 "Energy production and conversion:Putative translation initiation inhibitor, yjgF family:Molybdopterin biosynthesis enzyme:Molybdopterin biosynthesis enzymes:Glycine/D-amino acid oxidases (deaminating):Parvulin-like peptidyl-prolyl isomerase:Nitrate reductase beta subunit:ABC-type polysaccharide/polyol phosphate export systems, permease component:Type II secretory pathway, pseudopilin PulG:Nitrate reductase delta subunit:Nitrate reductase gamma subunit:Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain:FOG: HPt domain:Nitrate/nitrite transporter:Type II secretory pathway, ATPase PulE/Tfp pilus assembly pathway, ATPase PilB:Arabinose efflux permease:Molybdenum cofactor biosynthesis enzyme:Type II secretory pathway, component PulJ:Nitrate reductase alpha subunit:Amino acid transport and metabolism:Carbohydrate transport and metabolism:Coenzyme transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:Cell wall/membrane/envelope biogenesis:Cell motility:Posttranslational modification, protein turnover, chaperones:Inorganic ion transport and metabolism:Phenylalanine metabolism:Nitrogen metabolism:Microbial metabolism in diverse environments:ABC transporters:Two-component system:Bacterial secretion system:Sulfur relay system:Signal transduction mechanisms:molyb_syn:narI:narJ:2A0108:narG:narH:typeII_sec_gspG:IV_pilin_GFxxxE:moaA:Intracellular trafficking, secretion, and vesicular transport:Biosynthesis of cofactors, prosthetic groups, and carriers:Energy Metabolism:Amino Acid Metabolism:Genetic Information Processing:Folding Sorting and Degradation:Environmental Information Processing:Membrane Transport:Signal Transduction:Global:Metabolism:Energy metabolism:Anaerobic:Protein fate:Protein folding and stabilization:Protein and peptide secretion and trafficking:Transport and binding proteins:Anions:Cellular processes:Pathogenesis:Metabolism:Molybdopterin:Information storage and processing:Cellular processes and signaling:Metabolism" 344 "Energy production and conversion:Uroporphyrinogen-III methylase:Anaerobic dehydrogenases, typically selenocysteine-containing:Transcriptional regulator:FOG: Ankyrin repeat:Predicted permeases:Membrane protein TerC, possibly involved in tellurium resistance:Fe-S oxidoreductase:Succinate dehydrogenase/fumarate reductase, flavoprotein subunit:Uncharacterized membrane protein:Transcriptional regulator:Beta-propeller domains of methanol dehydrogenase type:Beta-lactamase class C and other penicillin binding proteins:Membrane transporters of cations and cationic drugs:AraC-type DNA-binding domain-containing proteins:Arabinose efflux permease:H+/citrate symporter:Uncharacterized protein conserved in bacteria:Hydroxylase for synthesis of 2-methylthio-cis-ribozeatin in tRNA:Predicted permease, DMT superfamily:Nucleotide transport and metabolism:Carbohydrate transport and metabolism:Coenzyme transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:Inorganic ion transport and metabolism:Porphyrin and chlorophyll metabolism:Nitrogen metabolism:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:General function prediction only:Function unknown:citMHS:cobA_cysG_Cterm:Defense mechanisms:Energy Metabolism:Metabolism:Poorly characterized:Metabolism:Cellular processes and signaling:Information storage and processing:Heme, porphyrin, and cobalamin:Biosynthesis of cofactors, prosthetic groups, and carriers:Carbohydrates, organic alcohols, and acids:Transport and binding proteins:Metabolism:Global:Metabolism of Cofactors and Vitamins" 345 "Energy production and conversion:Signal transduction histidine kinase:Methyl-accepting chemotaxis protein:NAD-dependent aldehyde dehydrogenases:Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases):Gamma-aminobutyrate permease and related permeases:Predicted metal-dependent hydrolase with the TIM-barrel fold:Outer membrane receptor proteins, mostly Fe transport:Predicted acyl-CoA transferases/carnitine dehydratase:Chemotaxis protein; stimulates methylation of MCP proteins:Acyl dehydratase:Adenosine deaminase:Chemotaxis response regulator containing a CheY-like receiver domain and a methylesterase domain:Permeases of the major facilitator superfamily:Histidine ammonia-lyase:ABC-type proline/glycine betaine transport system, ATPase component:Uncharacterized protein conserved in bacteria:L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily:Amino acid transport and metabolism:Nucleotide transport and metabolism:Lipid transport and metabolism:Cell wall/membrane/envelope biogenesis:Cell motility:Inorganic ion transport and metabolism:Glycolysis / Gluconeogenesis:Pentose and glucuronate interconversions:Ascorbate and aldarate metabolism:Fatty acid biosynthesis:Fatty acid metabolism:Valine leucine and isoleucine degradation:Lysine degradation:Arginine and proline metabolism:Histidine metabolism:Tryptophan metabolism:beta-Alanine metabolism:Glycerolipid metabolism:Pyruvate metabolism:Chloroalkane and chloroalkene degradation:Propanoate metabolism:Limonene and pinene degradation:Nitrogen metabolism:Biosynthesis of unsaturated fatty acids:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:ABC transporters:Two-component system:Bacterial chemotaxis:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:Function unknown:Signal transduction mechanisms:ogt:proV:hutH:Cellular processes and signaling:Amino acids, peptides and amines:Transport and binding proteins:DNA replication, recombination, and repair:DNA metabolism:Amino acids and amines:Energy metabolism:Metabolism:Metabolism:Global:Cell Motility:Cellular Processes:Signal Transduction:Membrane Transport:Environmental Information Processing:Xenobiotics Biodegradation and Metabolism:Metabolism of Terpenoids and Polyketides:Metabolism of Other Amino Acids:Amino Acid Metabolism:Lipid Metabolism:Energy Metabolism:Poorly characterized:Carbohydrate Metabolism:Metabolism" 346 "Energy production and conversion:Transcriptional regulator:ABC-type nitrate/sulfonate/bicarbonate transport system, permease component:Enoyl-CoA hydratase/carnithine racemase:Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases):ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component:Putative threonine efflux protein:Transcriptional regulators:Outer membrane receptor proteins, mostly Fe transport:Dioxygenases related to 2-nitropropane dioxygenase:Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases:Uncharacterized enzyme involved in biosynthesis of extracellular polysaccharides:Uncharacterized protein conserved in bacteria:Rhodanese-related sulfurtransferase:Predicted alpha/beta hydrolase:Predicted metal-dependent enzyme of the double-stranded beta helix superfamily:Amino acid transport and metabolism:Lipid transport and metabolism:Transcription:Inorganic ion transport and metabolism:Fatty acid metabolism:Valine leucine and isoleucine degradation:Geraniol degradation:Lysine degradation:Benzoate degradation:Tryptophan metabolism:beta-Alanine metabolism:Aminobenzoate degradation:Propanoate metabolism:Butanoate metabolism:Limonene and pinene degradation:Nitrogen metabolism:Caprolactam degradation:Aminoacyl-tRNA biosynthesis:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:ABC transporters:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:Function unknown:chol_sulf_TF:Environmental Information Processing:Translation:Genetic Information Processing:Xenobiotics Biodegradation and Metabolism:Metabolism of Terpenoids and Polyketides:Metabolism of Other Amino Acids:Amino Acid Metabolism:Lipid Metabolism:Energy Metabolism:Poorly characterized:Carbohydrate Metabolism:Metabolism:Information storage and processing:Metabolism:Metabolism:Global:Membrane Transport" 347 "Phosphoserine phosphatase:Predicted sugar nucleotidyltransferases:Flagellar hook-associated protein:Uncharacterized flagellar protein FlaG:Flagellin and related hook-associated proteins:Flagellar capping protein:Flagellin-specific chaperone FliS:Putative glycosyl/glycerophosphate transferases involved in teichoic acid biosynthesis TagF/TagB/EpsJ/RodC:2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase:Amino acid transport and metabolism:Coenzyme transport and metabolism:Cell wall/membrane/envelope biogenesis:Cell motility:Posttranslational modification, protein turnover, chaperones:Two-component system:Flagellar assembly:fliS:HAD-SF-IB:flgK_ends:flagell_flgL:Intracellular trafficking, secretion, and vesicular transport:Metabolism:Signal Transduction:Cellular Processes:Cell Motility:Cellular processes:Chemotaxis and motility:Unknown function:Enzymes of unknown specificity:Cellular processes and signaling:Environmental Information Processing" 348 "ATPases with chaperone activity, ATP-binding subunit:Serine/threonine protein phosphatase:Hemolysin-coregulated protein (uncharacterized):Uncharacterized protein conserved in bacteria:Uncharacterized conserved protein, contains FHA domain:Uncharacterized protein conserved in bacteria:Uncharacterized protein conserved in bacteria:Uncharacterized protein conserved in bacteria:Uncharacterized protein conserved in bacteria:Uncharacterized protein conserved in bacteria:Uncharacterized protein conserved in bacteria:Uncharacterized protein conserved in bacteria:Uncharacterized protein conserved in bacteria:Uncharacterized protein conserved in bacteria:Uncharacterized protein conserved in bacteria:Transcriptional regulator containing GAF, AAA-type ATPase, and DNA binding domains:Uncharacterized conserved protein:Transcription:Posttranslational modification, protein turnover, chaperones:Aminoacyl-tRNA biosynthesis:Bacterial secretion system:Function unknown:Signal transduction mechanisms:vgr_GE:VI_effect_Hcp1:VI_ClpV1:VI_chp_1:VI_IcmF:IV_VI_DotU:VI_chp_3:VI_chp_4:VI_FHA:VI_chp_2:VI_zyme:VI_chp_5:VI_chp_6:VI_chp_7:Translation:Cellular processes and signaling:Information storage and processing:Pathogenesis:Cellular processes:Genetic Information Processing:Membrane Transport:Environmental Information Processing:Poorly characterized" 349 "Dienelactone hydrolase and related enzymes:Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily):Signal transduction histidine kinase:Small-conductance mechanosensitive channel:Uncharacterized conserved protein, contains double-stranded beta-helix domain:Predicted aminopeptidases:Uncharacterized protein conserved in bacteria:Uncharacterized protein conserved in bacteria:Uncharacterized protein conserved in bacteria:Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain:Cell wall/membrane/envelope biogenesis:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:Function unknown:Signal transduction mechanisms:sensory_box:GGDEF:Metabolism:Cellular processes and signaling:Other:Signal transduction:Small molecule interactions:Regulatory functions:Poorly characterized" 350 "Energy production and conversion:Glutamine phosphoribosylpyrophosphate amidotransferase:Enolase:Threonine synthase:Valyl-tRNA synthetase:Lipoprotein signal peptidase:Penicillin tolerance protein:Cytochrome c, mono- and diheme variants:Cbb3-type cytochrome oxidase, cytochrome c subunit:Uncharacterized protein involved in biosynthesis of c-type cytochromes:Amino acid transport and metabolism:Nucleotide transport and metabolism:Carbohydrate transport and metabolism:Lipid transport and metabolism:Translation, ribosomal structure and biogenesis:Cell wall/membrane/envelope biogenesis:Posttranslational modification, protein turnover, chaperones:Glycolysis / Gluconeogenesis:Oxidative phosphorylation:Purine metabolism:Alanine aspartate and glutamate metabolism:Glycine serine and threonine metabolism:Valine leucine and isoleucine biosynthesis:Methane metabolism:Vitamin B6 metabolism:Terpenoid backbone biosynthesis:Aminoacyl-tRNA biosynthesis:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:RNA degradation:Protein export:lspA:ispH_lytB:thrC:valS:ccoO:ccoP:eno:purF:rimK_rel_E_lig:Intracellular trafficking, secretion, and vesicular transport:tRNA aminoacylation:Protein fate:Protein and peptide secretion and trafficking:Amino acid biosynthesis:Aspartate family:Biosynthesis of cofactors, prosthetic groups, and carriers:Other:Information storage and processing:Cellular processes and signaling:Metabolism:Purine ribonucleotide biosynthesis:Purines, pyrimidines, nucleosides, and nucleotides:Glycolysis/gluconeogenesis:Electron transport:Energy metabolism:Metabolism:Metabolism:Global:Folding Sorting and Degradation:Translation:Genetic Information Processing:Metabolism of Terpenoids and Polyketides:Metabolism of Cofactors and Vitamins:Amino Acid Metabolism:Nucleotide Metabolism:Energy Metabolism:Protein synthesis:Carbohydrate Metabolism" 351 "Phosphoglycerate dehydrogenase and related dehydrogenases:Dihydrofolate reductase:Transcriptional regulator:Signal transduction histidine kinase:Permeases of the drug/metabolite transporter (DMT) superfamily:Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain:Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases):Transcriptional regulator:Putative effector of murein hydrolase:Putative effector of murein hydrolase LrgA:Predicted pyrophosphatase:Uncharacterized conserved protein:Transcriptional regulators:Predicted flavoproteins:Uncharacterized conserved protein:2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase:Uncharacterized conserved protein:Predicted permeases:Amino acid transport and metabolism:Carbohydrate transport and metabolism:Coenzyme transport and metabolism:Lipid transport and metabolism:Transcription:Cell wall/membrane/envelope biogenesis:One carbon pool by folate:Vitamin B6 metabolism:Folate biosynthesis:Metabolic pathways:Two-component system:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:Function unknown:Signal transduction mechanisms:YaeB_AF0241:TIGR00275:rarD:2A78:TF_pcaQ:Environmental Information Processing:Information storage and processing:Metabolism of Cofactors and Vitamins:Cellular processes and signaling:Metabolism:Poorly characterized:Metabolism:Enzymes of unknown specificity:Unknown function:Amino acids, peptides and amines:Unknown substrate:Transport and binding proteins:DNA interactions:Regulatory functions:Metabolism:Global:Signal Transduction" 352 "Gamma-glutamyl phosphate reductase:Ribosomal protein L27:Glutamate 5-kinase:Ribosomal protein L19:Orotate phosphoribosyltransferase:Predicted GTPase:Exonuclease III:DNA-directed RNA polymerase, subunit K/omega:Amino acid transport and metabolism:Nucleotide transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:Replication, recombination and repair:Purine metabolism:Pyrimidine metabolism:Arginine and proline metabolism:Metabolic pathways:Ribosome:RNA polymerase:Base excision repair:General function prediction only:L27:pyrE:proA:xth:rpoZ:rplS_bact:proB:Obg_CgtA:Ribosomal proteins: synthesis and modification:Nucleotide Metabolism:Amino Acid Metabolism:Genetic Information Processing:Transcription:Translation:Replication and Repair:Global:Metabolism:Purines, pyrimidines, nucleosides, and nucleotides:Pyrimidine ribonucleotide biosynthesis:DNA metabolism:DNA replication, recombination, and repair:Transcription:DNA-dependent RNA polymerase:Protein synthesis:Other:Metabolism:Amino acid biosynthesis:Glutamate family:Information storage and processing:Metabolism:Poorly characterized" 353 "Energy production and conversion:Undecaprenyl pyrophosphate synthase:Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase:Imidazoleglycerol-phosphate synthase:Histidinol dehydrogenase:Glucosamine 6-phosphate synthetase, contains amidotransferase and phosphosugar isomerase domains:2-polyprenylphenol hydroxylase and related flavodoxin oxidoreductases:Uncharacterized conserved protein:Predicted dehydrogenases and related proteins:Predicted permeases:ABC-type antimicrobial peptide transport system, ATPase component:Predicted GTPases:Uncharacterized proteins, LmbE homologs:Gamma-glutamylcysteine synthetase:Uncharacterized protein conserved in bacteria:ABC-type arginine/histidine transport system, permease component:ABC-type arginine transport system, permease component:ABC-type transport system, involved in lipoprotein release, permease component:Amino acid transport and metabolism:Coenzyme transport and metabolism:Lipid transport and metabolism:Cell wall/membrane/envelope biogenesis:Alanine aspartate and glutamate metabolism:Histidine metabolism:Tyrosine metabolism:Phenylalanine metabolism:Phenylalanine tyrosine and tryptophan biosynthesis:Novobiocin biosynthesis:Glutathione metabolism:Amino sugar and nucleotide sugar metabolism:Terpenoid backbone biosynthesis:Aminoacyl-tRNA biosynthesis:Metabolic pathways:Biosynthesis of secondary metabolites:ABC transporters:General function prediction only:Function unknown:uppS:hisD:rlpA:hisF:glmS:hisC:glu_cys_ligase:HEQRo_perm_3TM:LolD_lipo_ex:lolCE:GTPase_EngA:Defense mechanisms:Cell envelope:Carbohydrate Metabolism:Amino Acid Metabolism:Metabolism of Other Amino Acids:Metabolism of Terpenoids and Polyketides:Biosynthesis of Other Secondary Metabolites:Genetic Information Processing:Translation:Environmental Information Processing:Membrane Transport:Global:Metabolism:Central intermediary metabolism:Amino sugars:Protein synthesis:Other:Protein fate:Protein and peptide secretion and trafficking:Transport and binding proteins:Amino acids, peptides and amines:Amino acid biosynthesis:Histidine family:Biosynthesis of cofactors, prosthetic groups, and carriers:Glutathione and analogs:Metabolism:Other:Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides:Cellular processes and signaling:Metabolism:Poorly characterized" 354 "Energy production and conversion:Predicted ATPase of the PP-loop superfamily implicated in cell cycle control:Ribosomal protein L31:Uncharacterized conserved protein:rRNA methylase:Uncharacterized protein conserved in bacteria:Predicted permeases:Membrane-fusion protein:Ferredoxin:Transcriptional regulator:Predicted RNA-binding protein containing KH domain, possibly ribosomal protein:F0F1-type ATP synthase, subunit I:Predicted transcriptional regulator, BolA superfamily:Cell cycle control, cell division, chromosome partitioning:Translation, ribosomal structure and biogenesis:Transcription:Cell wall/membrane/envelope biogenesis:Aminoacyl-tRNA biosynthesis:ABC transporters:Ribosome:General function prediction only:Function unknown:rRNA_methyl_1:L31:TIGR00149_YbjQ:RNA_bind_YhbY:RND_mfp:Cellular processes and signaling:Translation:Environmental Information Processing:Membrane Transport:Protein synthesis:Ribosomal proteins: synthesis and modification:tRNA and rRNA base modification:Transport and binding proteins:Unknown substrate:Unknown function:Enzymes of unknown specificity:General:Information storage and processing:Genetic Information Processing:Metabolism:Poorly characterized" 355 "Predicted hydrolase of the alpha/beta-hydrolase fold:Transcriptional regulator:Glycine/D-amino acid oxidases (deaminating):ABC-type spermidine/putrescine transport system, permease component I:ABC-type spermidine/putrescine transport system, permease component II:Predicted membrane protein:Outer membrane receptor proteins, mostly Fe transport:Transposase and inactivated derivatives:Precorrin-6x reductase:Arabinose efflux permease:ABC-type spermidine/putrescine transport systems, ATPase components:Uncharacterized protein conserved in bacteria:Predicted periplasmic lipoprotein:Amino acid transport and metabolism:Carbohydrate transport and metabolism:Coenzyme transport and metabolism:Transcription:Replication, recombination and repair:Inorganic ion transport and metabolism:Porphyrin and chlorophyll metabolism:Metabolic pathways:General function prediction only:Function unknown:potA:TonB-siderophor:Metabolism of Cofactors and Vitamins:Metabolism:Poorly characterized:Metabolism:Information storage and processing:Porins:Amino acids, peptides and amines:Transport and binding proteins:Metabolism:Global" 356 "Energy production and conversion:Anthranilate/para-aminobenzoate synthases component I:Pyridoxamine-phosphate oxidase:Predicted epimerase, PhzC/PhzF homolog:Uncharacterized NAD(FAD)-dependent dehydrogenases:2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases:Glycine/D-amino acid oxidases (deaminating):Isochorismate hydrolase:3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase:Amino acid transport and metabolism:Coenzyme transport and metabolism:Phenylalanine tyrosine and tryptophan biosynthesis:Cyanoamino acid metabolism:Metabolic pathways:Biosynthesis of secondary metabolites:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:pdxH:PhzF_family:Metabolism:Amino Acid Metabolism:Metabolism of Other Amino Acids:Global:Metabolism:Cellular processes:Toxin production and resistance:Biosynthesis of cofactors, prosthetic groups, and carriers:Pyridoxine:Metabolism:Poorly characterized" 357 "ABC-type phosphate transport system, periplasmic component:Alkaline phosphatase:Transcriptional regulators:Predicted extracellular nuclease:Putative hemolysin:Predicted phosphatase:ABC-type phosphate/phosphonate transport system, periplasmic component:Metal-dependent hydrolase involved in phosphonate metabolism:Phospholipase C:Uncharacterized enzyme of phosphonate metabolism:Uncharacterized enzyme of phosphonate metabolism:Uncharacterized enzyme of phosphonate metabolism:Uncharacterized enzyme of phosphonate metabolism:ABC-type phosphate/phosphonate transport system, ATPase component:ABC-type phosphate/phosphonate transport system, permease component:ABC-type phosphonate transport system, ATPase component:Predicted HD phosphohydrolase:Transcription:Cell wall/membrane/envelope biogenesis:Inorganic ion transport and metabolism:Inositol phosphate metabolism:Glycerophospholipid metabolism:Ether lipid metabolism:Aminobenzoate degradation:Folate biosynthesis:Metabolic pathways:Microbial metabolism in diverse environments:ABC transporters:Two-component system:General function prediction only:PhnE:3A0109s03R:ABC_phnC:phosphono_phnM:CP_lyasePhnK:C_P_lyase_phnF:Phn-HD:PhnH_redo:PhnG_redo:PC_PLC:Cellular processes and signaling:Carbohydrate Metabolism:Lipid Metabolism:Metabolism of Cofactors and Vitamins:Xenobiotics Biodegradation and Metabolism:Environmental Information Processing:Membrane Transport:Signal Transduction:Global:Metabolism:Central intermediary metabolism:Phosphorus compounds:Energy metabolism:Other:Regulatory functions:DNA interactions:Transport and binding proteins:Anions:Cellular processes:Pathogenesis:Information storage and processing:Metabolism:Metabolism:Poorly characterized" 358 "Energy production and conversion:Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase:Dihydroxyacid dehydratase/phosphogluconate dehydratase:Glutamine synthetase:6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase:Glucose-6-phosphate 1-dehydrogenase:Amino acid transporters:Glycerol kinase:Glycerol-3-phosphate dehydrogenase:Glycerol uptake facilitator and related permeases (Major Intrinsic Protein Family):2-keto-3-deoxy-6-phosphogluconate aldolase:Glucokinase:NADH:ubiquinone oxidoreductase subunit 3 (chain A):Amidases related to nicotinamidase:Transcriptional regulators of sugar metabolism:Transcriptional regulators:Transcriptional regulators:Sugar phosphate permease:Uncharacterized conserved protein:H+/gluconate symporter and related permeases:Cytochrome c553:Cytochrome c:Gluconate kinase:Predicted N-formylglutamate amidohydrolase:Amino acid transport and metabolism:Carbohydrate transport and metabolism:Transcription:Glycolysis / Gluconeogenesis:Pentose phosphate pathway:Pentose and glucuronate interconversions:Galactose metabolism:Oxidative phosphorylation:Alanine aspartate and glutamate metabolism:Arginine and proline metabolism:Glutathione metabolism:Starch and sucrose metabolism:Amino sugar and nucleotide sugar metabolism:Streptomycin biosynthesis:Glycerolipid metabolism:Glycerophospholipid metabolism:Glyoxylate and dicarboxylate metabolism:Nitrogen metabolism:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:Two-component system:Secondary metabolites biosynthesis, transport and catabolism:Function unknown:YbaK_EbsC:glpT:glk:gntP:MIP:zwf:eda:edd:pgl:glycerol_kin:therm_gnt_kin:GAPDH-I:General:Carbohydrate Metabolism:Energy Metabolism:Lipid Metabolism:Amino Acid Metabolism:Metabolism of Other Amino Acids:Biosynthesis of Other Secondary Metabolites:Environmental Information Processing:Signal Transduction:Global:Metabolism:Energy metabolism:Entner-Doudoroff:Glycolysis/gluconeogenesis:Pentose phosphate pathway:Other:Transport and binding proteins:Unknown substrate:Carbohydrates, organic alcohols, and acids:Other:Unknown function:Metabolism:Information storage and processing:Metabolism:Poorly characterized" 359 "Energy production and conversion:Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases:Amino acid transporters:Transcriptional regulator:Predicted oxidoreductases (related to aryl-alcohol dehydrogenases):Na+/phosphate symporter:Alcohol dehydrogenase, class IV:Acetyltransferases, including N-acetylases of ribosomal proteins:Acyl-CoA dehydrogenases:AraC-type DNA-binding domain-containing proteins:Putative NADPH-quinone reductase (modulator of drug activity B):Arabinose efflux permease:Predicted permeases:Uncharacterized protein conserved in bacteria:ABC-type arginine/histidine transport system, permease component:Type II secretory pathway, component PulJ:ABC-type anion transport system, duplicated permease component:Amino acid transport and metabolism:Carbohydrate transport and metabolism:Lipid transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:Inorganic ion transport and metabolism:Fructose and mannose metabolism:Arginine and proline metabolism:Phenylalanine metabolism:Bisphenol degradation:Tryptophan metabolism:Cyanoamino acid metabolism:Chloroalkane and chloroalkene degradation:Aminobenzoate degradation:Styrene degradation:Butanoate metabolism:Metabolic pathways:Microbial metabolism in diverse environments:ABC transporters:Bacterial secretion system:General function prediction only:Function unknown:HEQRo_perm_3TM:Intracellular trafficking, secretion, and vesicular transport:Amino Acid Metabolism:Metabolism:Carbohydrate Metabolism:Poorly characterized:Cellular processes and signaling:Information storage and processing:Amino acids, peptides and amines:Transport and binding proteins:Metabolism:Global:Membrane Transport:Environmental Information Processing:Xenobiotics Biodegradation and Metabolism:Metabolism of Other Amino Acids:Metabolism" 360 "Geranylgeranyl pyrophosphate synthase:Protein chain release factor A:Predicted S-adenosylmethionine-dependent methyltransferase:Mismatch repair ATPase (MutS family):Phosphate/sulphate permeases:Aspartate/tyrosine/aromatic aminotransferase:Membrane GTPase LepA:CDP-diglyceride synthetase:2-methylthioadenine synthetase:UDP-N-acetylglucosamine enolpyruvyl transferase:Homoserine acetyltransferase:Lysophospholipase:Amino acid transport and metabolism:Coenzyme transport and metabolism:Lipid transport and metabolism:Translation, ribosomal structure and biogenesis:Replication, recombination and repair:Cell wall/membrane/envelope biogenesis:Inorganic ion transport and metabolism:Alanine aspartate and glutamate metabolism:Cysteine and methionine metabolism:Valine leucine and isoleucine biosynthesis:Amino sugar and nucleotide sugar metabolism:Peptidoglycan biosynthesis:Glycerophospholipid metabolism:Terpenoid backbone biosynthesis:Sulfur metabolism:Metabolic pathways:Biosynthesis of secondary metabolites:Mismatch repair:General function prediction only:prfA:TIGR00089:TIGR00091:small_GTP:mutS1:murA:homoserO_Ac_trn:Information storage and processing:Carbohydrate Metabolism:Energy Metabolism:Lipid Metabolism:Amino Acid Metabolism:Glycan Biosynthesis and Metabolism:Metabolism of Terpenoids and Polyketides:Genetic Information Processing:Replication and Repair:Global:Metabolism:DNA metabolism:DNA replication, recombination, and repair:Protein synthesis:tRNA and rRNA base modification:Translation factors:Unknown function:General:Amino acid biosynthesis:Aspartate family:Cell envelope:Biosynthesis and degradation of murein sacculus and peptidoglycan:Metabolism:Cellular processes and signaling:Metabolism:Poorly characterized" 361 "Energy production and conversion:Glutamate synthase domain 2:Ribosomal protein L31:Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases:Predicted oxidoreductases (related to aryl-alcohol dehydrogenases):NAD-dependent aldehyde dehydrogenases:Predicted membrane protein, hemolysin III homolog:Ketopantoate reductase:ABC-type proline/glycine betaine transport systems, periplasmic components:Choline dehydrogenase and related flavoproteins:Phosphoenolpyruvate carboxylase:3-carboxymuconate cyclase:Uncharacterized conserved protein:Uncharacterized conserved protein:Putative Zn-dependent protease, contains TPR repeats:Amino acid transport and metabolism:Carbohydrate transport and metabolism:Coenzyme transport and metabolism:Translation, ribosomal structure and biogenesis:Arginine and proline metabolism:Pyruvate metabolism:Methane metabolism:Carbon fixation pathways in prokaryotes:Pantothenate and CoA biosynthesis:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:ABC transporters:Ribosome:General function prediction only:Function unknown:L31:apbA_panE:rpmJ_bact:hlyIII:AcOrn-deacetyl:gcw_chp:ABC_choline_bnd:Metabolism:Carbohydrate Metabolism:Energy Metabolism:Amino Acid Metabolism:Metabolism of Cofactors and Vitamins:Genetic Information Processing:Translation:Environmental Information Processing:Membrane Transport:Global:Metabolism:Protein synthesis:Ribosomal proteins: synthesis and modification:Transport and binding proteins:Amino acids, peptides and amines:Amino acid biosynthesis:Glutamate family:Biosynthesis of cofactors, prosthetic groups, and carriers:Pantothenate and coenzyme A:Information storage and processing:Metabolism:Poorly characterized" 362 "Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases:Transcriptional regulator:ABC-type nitrate/sulfonate/bicarbonate transport system, permease component:Spermidine/putrescine-binding periplasmic protein:ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components:ABC-type amino acid transport system, permease component:Periplasmic protein TonB, links inner and outer membranes:Biopolymer transport proteins:ABC-type amino acid transport/signal transduction systems, periplasmic component/domain:Biopolymer transport protein:ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component:ABC-type polar amino acid transport system, ATPase component:Putative threonine efflux protein:DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog:AraC-type DNA-binding domain-containing proteins:Arylsulfatase A and related enzymes:Isopenicillin N synthase and related dioxygenases:ABC-type spermidine/putrescine transport systems, ATPase components:ABC-type anion transport system, duplicated permease component:Amino acid transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:Cell wall/membrane/envelope biogenesis:Inorganic ion transport and metabolism:Arginine and proline metabolism:Phenylalanine metabolism:Tryptophan metabolism:Cyanoamino acid metabolism:Aminobenzoate degradation:Styrene degradation:Microbial metabolism in diverse environments:ABC transporters:RNA polymerase:General function prediction only:Signal transduction mechanisms:potA:tonB_Cterm:HEQRo_perm_3TM:sigma70-ECF:Intracellular trafficking, secretion, and vesicular transport:Metabolism:Cellular processes and signaling:Information storage and processing:Cations and iron carrying compounds:Amino acids, peptides and amines:Transport and binding proteins:Metabolism:Metabolism:Global:Membrane Transport:Environmental Information Processing:Transcription:Genetic Information Processing:Xenobiotics Biodegradation and Metabolism:Metabolism of Other Amino Acids:Amino Acid Metabolism:Poorly characterized" 363 "Uncharacterized membrane protein:Uncharacterized protein involved in formation of curli polymers:Predicted membrane protein/domain:Uncharacterized conserved protein (some members contain a von Willebrand factor type A (vWA) domain):FOG: GGDEF domain:Serine phosphatase RsbU, regulator of sigma subunit:Predicted acetyltransferase:Chain length determinant protein:Uncharacterized protein conserved in bacteria:Uncharacterized protein conserved in bacteria:Transcription:Cell wall/membrane/envelope biogenesis:General function prediction only:Function unknown:Signal transduction mechanisms:GGDEF:Information storage and processing:Other:Signal transduction:Cellular processes and signaling:Poorly characterized" 364 "Pseudouridylate synthase:Dephospho-CoA kinase:Chemotaxis protein histidine kinase and related kinases:cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases:Spermidine/putrescine-binding periplasmic protein:Shikimate kinase:FOG: CheY-like receiver:Chemotaxis signal transduction protein:Methyl-accepting chemotaxis protein:Methylase of chemotaxis methyl-accepting proteins:Uncharacterized protein containing LysM domain:Type II secretory pathway, prepilin signal peptidase PulO and related peptidases:Chemotaxis response regulator containing a CheY-like receiver domain and a methylesterase domain:Tfp pilus assembly protein PilN:Tfp pilus assembly protein PilO:Tfp pilus assembly protein PilP:Tfp pilus assembly protein FimV:Type II secretory pathway, component HofQ:Tfp pilus assembly protein, ATPase PilM:Tfp pilus assembly protein, ATPase PilU:Amino acid transport and metabolism:Coenzyme transport and metabolism:Translation, ribosomal structure and biogenesis:Cell motility:Posttranslational modification, protein turnover, chaperones:Phenylalanine tyrosine and tryptophan biosynthesis:Pantothenate and CoA biosynthesis:Metabolic pathways:Biosynthesis of secondary metabolites:Two-component system:Function unknown:Signal transduction mechanisms:hisT_truA:TIGR00152:pilM:pilT_fam:IV_pilus_PilQ:FimV_Cterm:Intracellular trafficking, secretion, and vesicular transport:Information storage and processing:Surface structures:Cell envelope:Pantothenate and coenzyme A:Biosynthesis of cofactors, prosthetic groups, and carriers:Chemotaxis and motility:Cellular processes:tRNA and rRNA base modification:Protein synthesis:Metabolism:Metabolism:Global:Signal Transduction:Environmental Information Processing:Metabolism of Cofactors and Vitamins:Amino Acid Metabolism:Poorly characterized:Metabolism:Cellular processes and signaling" 365 "Acetyl-CoA acetyltransferase:Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases:ABC-type sugar transport system, permease component:Glutathione S-transferase:Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases):Gamma-aminobutyrate permease and related permeases:ABC-type sugar transport systems, permease components:Uncharacterized proteins, homologs of lactam utilization protein B:ABC-type sugar transport system, periplasmic component:Allophanate hydrolase subunit 2:Short chain fatty acids transporter:Allophanate hydrolase subunit 1:Sugar phosphate permease:H+/gluconate symporter and related permeases:Predicted outer membrane protein:Carbohydrate-selective porin:ABC-type sugar transport systems, ATPase components:Uncharacterized conserved protein:Uncharacterized protein with a C-terminal OMP (outer membrane protein) domain:Amino acid transport and metabolism:Carbohydrate transport and metabolism:Lipid transport and metabolism:Cell wall/membrane/envelope biogenesis:Posttranslational modification, protein turnover, chaperones:Glycolysis / Gluconeogenesis:Fatty acid metabolism:Synthesis and degradation of ketone bodies:Valine leucine and isoleucine degradation:Lysine degradation:Tyrosine metabolism:Benzoate degradation:Tryptophan metabolism:Pyruvate metabolism:Glyoxylate and dicarboxylate metabolism:Propanoate metabolism:Styrene degradation:Butanoate metabolism:Methane metabolism:Carbon fixation pathways in prokaryotes:Terpenoid backbone biosynthesis:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:Two-component system:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:Function unknown:maiA:autotrans_barl:AcCoA-C-Actrans:PHB_DH:Ac_CoA_lig_AcsA:Energy metabolism:Carbohydrate Metabolism:Energy Metabolism:Lipid Metabolism:Amino Acid Metabolism:Metabolism of Terpenoids and Polyketides:Xenobiotics Biodegradation and Metabolism:Environmental Information Processing:Signal Transduction:Global:Metabolism:Metabolism:Amino acids and amines:Fatty acid and phospholipid metabolism:Other:Cellular processes:Pathogenesis:Cellular processes and signaling:Metabolism:Poorly characterized" 366 "Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II:Amino acid transporters:Transcriptional regulator:Signal transduction histidine kinase:ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components:Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases):Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs:Rad3-related DNA helicases:Predicted metal-dependent protease of the PAD1/JAB1 superfamily:Acetyltransferases, including N-acetylases of ribosomal proteins:Acyl-CoA dehydrogenases:Arabinose efflux permease:Predicted transcriptional regulator:Predicted transcriptional regulator:Response regulator:Amino acid transport and metabolism:Carbohydrate transport and metabolism:Lipid transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:Replication, recombination and repair:Inorganic ion transport and metabolism:Fatty acid biosynthesis:Fatty acid metabolism:Valine leucine and isoleucine degradation:beta-Alanine metabolism:Propanoate metabolism:Butanoate metabolism:Aminoacyl-tRNA biosynthesis:Biosynthesis of unsaturated fatty acids:Metabolic pathways:Biosynthesis of secondary metabolites:ABC transporters:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:Signal transduction mechanisms:sensory_box:efflux_EmrB:Metabolism:Global:Membrane Transport:Environmental Information Processing:Translation:Genetic Information Processing:Metabolism of Other Amino Acids:Amino Acid Metabolism:Metabolism:Lipid Metabolism:Metabolism:Carbohydrate Metabolism:Poorly characterized:Cellular processes and signaling:Information storage and processing:Other:Transport and binding proteins:Small molecule interactions:Regulatory functions" 367 "Energy production and conversion:Glycine cleavage system protein P (pyridoxal-binding), C-terminal domain:Transcriptional regulator:Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL homologs:Predicted metal-dependent hydrolase with the TIM-barrel fold:Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS/CutS homologs:Predicted aminopeptidases:P pilus assembly protein, chaperone PapD:Poly(3-hydroxyalkanoate) synthetase:Uncharacterized secreted protein:Amino acid transport and metabolism:Lipid transport and metabolism:Transcription:Cell motility:Glycine serine and threonine metabolism:Butanoate metabolism:Metabolic pathways:General function prediction only:Function unknown:gcvP:PHA_synth_II:Intracellular trafficking, secretion, and vesicular transport:Poorly characterized:Carbohydrate Metabolism:Amino Acid Metabolism:Global:Metabolism:Energy metabolism:Amino acids and amines:Fatty acid and phospholipid metabolism:Biosynthesis:Information storage and processing:Cellular processes and signaling:Metabolism:Metabolism" 368 "1-acyl-sn-glycerol-3-phosphate acyltransferase:Biotin synthase and related enzymes:Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases:Transcriptional regulator:Mg2+ and Co2+ transporters:Glutathione S-transferase:Cell wall-associated hydrolases (invasion-associated proteins):ABC-type amino acid transport/signal transduction systems, periplasmic component/domain:Fatty-acid desaturase:Flagellar basal body-associated protein:Acyl-CoA hydrolase:Predicted membrane protein:Uncharacterized protein conserved in bacteria:Amino acid transport and metabolism:Nucleotide transport and metabolism:Carbohydrate transport and metabolism:Coenzyme transport and metabolism:Lipid transport and metabolism:Transcription:Cell wall/membrane/envelope biogenesis:Cell motility:Posttranslational modification, protein turnover, chaperones:Inorganic ion transport and metabolism:Purine metabolism:Glutathione metabolism:Biotin metabolism:Aminoacyl-tRNA biosynthesis:Metabolic pathways:Ribosome:General function prediction only:Function unknown:Signal transduction mechanisms:TIGR00052:bioB:TIGR00701:Poorly characterized:Nucleotide Metabolism:Metabolism of Other Amino Acids:Metabolism of Cofactors and Vitamins:Genetic Information Processing:Translation:Global:Metabolism:Hypothetical proteins:Conserved:Unknown function:Enzymes of unknown specificity:Biosynthesis of cofactors, prosthetic groups, and carriers:Biotin:Information storage and processing:Cellular processes and signaling:Metabolism:Metabolism" 369 "4-aminobutyrate aminotransferase and related aminotransferases:Selenocysteine lyase:Membrane-fusion protein:Non-ribosomal peptide synthetase modules and related proteins:Uncharacterized conserved protein:Zn-dependent dipeptidase, microsomal dipeptidase homolog:Predicted thioesterase involved in non-ribosomal peptide biosynthesis:Uncharacterized protein conserved in bacteria:Lysine/ornithine N-monooxygenase:ABC-type siderophore export system, fused ATPase and permease components:Amino acid transport and metabolism:Cell wall/membrane/envelope biogenesis:Inorganic ion transport and metabolism:Glycine serine and threonine metabolism:Metabolic pathways:Microbial metabolism in diverse environments:ABC transporters:Secondary metabolites biosynthesis, transport and catabolism:Function unknown:dat:cyc_pep_trnsptr:TAT_signal_seq:RND_mfp:AA-adenyl-dom:Unknown substrate:Amino Acid Metabolism:Environmental Information Processing:Membrane Transport:Global:Metabolism:Central intermediary metabolism:Other:Protein fate:Protein and peptide secretion and trafficking:Transport and binding proteins:Metabolism:Other:Cellular processes and signaling:Metabolism:Poorly characterized" 370 "DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog:FOG: GGDEF domain:Bacterial lipocalin:Negative regulator of sigma E activity:Predicted outer membrane lipoprotein:Uncharacterized protein conserved in archaea:Transcription:Cell wall/membrane/envelope biogenesis:Posttranslational modification, protein turnover, chaperones:RNA polymerase:Function unknown:Signal transduction mechanisms:GGDEF:sigma70-ECF:Transcription:Cellular processes and signaling:Poorly characterized:Genetic Information Processing:Other:Signal transduction:Information storage and processing" 371 "Energy production and conversion:ABC-type phosphate transport system, periplasmic component:Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain:Stress-induced morphogen (activity unknown):Transcriptional regulator:Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily):Phosphate uptake regulator:Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain:Flavodoxin reductases (ferredoxin-NADPH reductases) family 1:ABC-type phosphate transport system, ATPase component:Predicted metal-dependent hydrolase:Uncharacterized protein conserved in bacteria:Chain length determinant protein:Uncharacterized protein conserved in bacteria:ABC-type phosphate transport system, auxiliary component:Signal transduction histidine kinase:Transcription:Cell wall/membrane/envelope biogenesis:Posttranslational modification, protein turnover, chaperones:Inorganic ion transport and metabolism:Aminoacyl-tRNA biosynthesis:ABC transporters:Two-component system:Ribosome:General function prediction only:Function unknown:Signal transduction mechanisms:3a0107s01c2:3a0107s02c:phoU_full:ptsS_2:PhoB:phoR_proteo:trp_arylform:Information storage and processing:Two-component systems:Signal transduction:Anions:Transport and binding proteins:Amino acids and amines:Energy metabolism:Genetic Information Processing:Signal Transduction:Membrane Transport:Environmental Information Processing:Poorly characterized:Translation:Metabolism:Cellular processes and signaling" 372 "Shikimate 5-dehydrogenase:Short-chain dehydrogenases of various substrate specificities:Pseudouridylate synthases, 23S RNA-specific:Transcriptional regulator:Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily):Signal transduction histidine kinase:ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components:Predicted Fe-S-cluster oxidoreductase:Enzyme related to GTP cyclohydrolase I:Type II secretory pathway, component PulD:Acetyltransferases, including N-acetylases of ribosomal proteins:AraC-type DNA-binding domain-containing proteins:Putative glycerate kinase:Predicted membrane protein:5-carboxymethyl-2-hydroxymuconate isomerase:Inner membrane protein involved in colicin E2 resistance:Amino acid transport and metabolism:Carbohydrate transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:Cell motility:Inorganic ion transport and metabolism:Glycine serine and threonine metabolism:Tyrosine metabolism:Benzoate degradation:Phenylalanine tyrosine and tryptophan biosynthesis:Glyoxylate and dicarboxylate metabolism:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:ABC transporters:Bacterial secretion system:General function prediction only:Function unknown:Signal transduction mechanisms:SsuA_fam:type_II_gspD:QueF:argP:Intracellular trafficking, secretion, and vesicular transport:Defense mechanisms:Information storage and processing:Carbohydrate Metabolism:Amino Acid Metabolism:Xenobiotics Biodegradation and Metabolism:Environmental Information Processing:Membrane Transport:Global:Metabolism:Regulatory functions:DNA interactions:Transcription:RNA processing:Protein fate:Protein and peptide secretion and trafficking:Transport and binding proteins:Other:Metabolism:Cellular processes and signaling:Metabolism:Poorly characterized" 373 "Energy production and conversion:Putative translation initiation inhibitor, yjgF family:Acetyltransferases:Phosphoserine phosphatase:Transcriptional regulator:NADPH:quinone reductase and related Zn-dependent oxidoreductases:Nitroreductase:Hydrolases of the alpha/beta superfamily:Phosphoenolpyruvate-protein kinase (PTS system EI component in bacteria):Uncharacterized protein conserved in bacteria:Transcriptional regulator:Phosphatidylserine/phosphatidylglycerophosphate/cardiolipin synthases and related enzymes:Transcriptional regulators:Acyl-CoA dehydrogenases:3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases:AraC-type DNA-binding domain-containing proteins:P pilus assembly protein, pilin FimA:Transcriptional regulator containing GAF, AAA-type ATPase, and DNA binding domains:Hydroxypyruvate isomerase:2-hydroxychromene-2-carboxylate isomerase:Glyoxylate carboligase:Short-chain alcohol dehydrogenase of unknown specificity:Amino acid transport and metabolism:Carbohydrate transport and metabolism:Lipid transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:Cell motility:Geraniol degradation:Glycerophospholipid metabolism:Naphthalene degradation:Glyoxylate and dicarboxylate metabolism:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:Function unknown:Signal transduction mechanisms:PTBA:HAD-SF-IB:glyox_carbo_lig:tartro_sem_red:quinone_pig3:OH-pyruv-isom:Intracellular trafficking, secretion, and vesicular transport:Signal transduction:Enzymes of unknown specificity:Unknown function:PTS:Information storage and processing:Cellular processes and signaling:Metabolism:Poorly characterized:Metabolism:Metabolism:Global:Xenobiotics Biodegradation and Metabolism:Metabolism of Terpenoids and Polyketides:Lipid Metabolism:Carbohydrate Metabolism" 374 "Energy production and conversion:L-asparaginase/archaeal Glu-tRNAGln amidotransferase subunit D:Coproporphyrinogen III oxidase:Spermidine synthase:Glycerol kinase:Signal transduction histidine kinase:Predicted thioesterase:ABC-type multidrug transport system, permease component:Lactate dehydrogenase and related dehydrogenases:Na+/alanine symporter:Primosomal protein N' (replication factor Y) - superfamily II helicase:Predicted transcriptional regulator containing the HTH domain:Predicted signal transduction protein:Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains:AraC-type DNA-binding domain-containing proteins:Lysophospholipase:Uncharacterized conserved protein:Predicted SAM-dependent methyltransferase:4-hydroxybenzoate synthetase (chorismate lyase):3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase:Uncharacterized protein conserved in bacteria:Response regulator containing a CheY-like receiver domain and a GGDEF domain:Signal transduction histidine kinase regulating C4-dicarboxylate transport system:Predicted soluble lytic transglycosylase fused to an ABC-type amino acid-binding protein:Site-specific recombinase XerD:Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain:Amino acid transport and metabolism:Coenzyme transport and metabolism:Lipid transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:Replication, recombination and repair:Cell wall/membrane/envelope biogenesis:Pentose phosphate pathway:Ubiquinone and other terpenoid-quinone biosynthesis:Alanine aspartate and glutamate metabolism:Phenylalanine tyrosine and tryptophan biosynthesis:Cyanoamino acid metabolism:Glycerolipid metabolism:Porphyrin and chlorophyll metabolism:Nitrogen metabolism:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:ABC transporters:Two-component system:Homologous recombination:General function prediction only:Function unknown:Signal transduction mechanisms:YbaK_EbsC:GGDEF:TIGR00281:priA:agcS:glycerol_kin:DAHP_synth_II:recomb_XerD:Defense mechanisms:Other:Energy metabolism:Metabolism:Global:Metabolism:Signal Transduction:Membrane Transport:Environmental Information Processing:Replication and Repair:Genetic Information Processing:Metabolism of Cofactors and Vitamins:Metabolism of Other Amino Acids:Amino Acid Metabolism:Lipid Metabolism:Energy Metabolism:Other:Carbohydrate Metabolism:Information storage and processing:Cellular processes and signaling:Metabolism:Poorly characterized:Signal transduction:Aromatic amino acid family:Amino acid biosynthesis:General:Unknown function:Chromosome-associated proteins:DNA replication, recombination, and repair:DNA metabolism" 375 "Energy production and conversion:Fructose-2,6-bisphosphatase:Uncharacterized NAD(FAD)-dependent dehydrogenases:Predicted dehydrogenase:Transcriptional regulator:Fucose permease:Membrane protein TerC, possibly involved in tellurium resistance:16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases:Transcriptional regulator:Predicted transcriptional regulators:Predicted metal-dependent hydrolase:Predicted membrane protein/domain:Uncharacterized conserved protein:AraC-type DNA-binding domain-containing proteins:2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase:Protein related to penicillin acylase:Arabinose efflux permease:3-methyladenine DNA glycosylase:H+/citrate symporter:Predicted membrane protein:Small-conductance mechanosensitive channel:Lipid A core - O-antigen ligase and related enzymes:Predicted ferric reductase:Kef-type K+ transport system, predicted NAD-binding component:Predicted integral membrane protein:Carbohydrate transport and metabolism:Coenzyme transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:Replication, recombination and repair:Cell wall/membrane/envelope biogenesis:Inorganic ion transport and metabolism:Penicillin and cephalosporin biosynthesis:Biosynthesis of secondary metabolites:Base excision repair:General function prediction only:Function unknown:tag:TIGR00697:citMHS:2a37:Replication and Repair:Genetic Information Processing:Biosynthesis of Other Secondary Metabolites:Metabolism:Poorly characterized:Metabolism:Cellular processes and signaling:Information storage and processing:Conserved:Hypothetical proteins:Cations and iron carrying compounds:Carbohydrates, organic alcohols, and acids:Transport and binding proteins:DNA replication, recombination, and repair:DNA metabolism:Metabolism:Global" 376 "Conserved domain frequently associated with peptide methionine sulfoxide reductase:Molybdopterin converting factor, large subunit:Molybdenum cofactor biosynthesis enzyme:Glutathione peroxidase:Universal stress protein UspA and related nucleotide-binding proteins:Integral membrane protein, interacts with FtsH:Predicted xylanase/chitin deacetylase:ABC-type amino acid transport/signal transduction systems, periplasmic component/domain:Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs:Amidases related to nicotinamidase:Phage shock protein A (IM30), suppresses sigma54-dependent transcription:Molybdopterin converting factor, small subunit:Transthyretin-like protein:Outer membrane lipoprotein:Alkylated DNA repair protein:Uncharacterized conserved protein:Uncharacterized protein conserved in bacteria:Uncharacterized protein conserved in bacteria:Uncharacterized conserved small protein:Amino acid transport and metabolism:Carbohydrate transport and metabolism:Coenzyme transport and metabolism:Transcription:Replication, recombination and repair:Cell wall/membrane/envelope biogenesis:Posttranslational modification, protein turnover, chaperones:Purine metabolism:Glutathione metabolism:Arachidonic acid metabolism:Metabolic pathways:Microbial metabolism in diverse environments:Sulfur relay system:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:Function unknown:Signal transduction mechanisms:TIGR00357:moaC:3A0103s03R:moaD:hdxy_isourate:uraD_N-term-dom:Poorly characterized:Lipid Metabolism:Nucleotide Metabolism:Metabolism of Other Amino Acids:Genetic Information Processing:Folding Sorting and Degradation:Global:Metabolism:Purines, pyrimidines, nucleosides, and nucleotides:Other:Transport and binding proteins:Amino acids, peptides and amines:Cellular processes:Adaptations to atypical conditions:Biosynthesis of cofactors, prosthetic groups, and carriers:Molybdopterin:Information storage and processing:Cellular processes and signaling:Metabolism:Metabolism" 377 "Zn-dependent hydrolases, including glyoxylases:Na+-driven multidrug efflux pump:Transcriptional regulator:Organic radical activating enzymes:Glutathione S-transferase:Permeases of the drug/metabolite transporter (DMT) superfamily:Predicted Fe-S-cluster oxidoreductase:Uncharacterized membrane protein, putative virulence factor:Fucose permease:3-dehydroquinate dehydratase II:Amino acid permeases:Predicted membrane protein:Purine-cytosine permease and related proteins:Acyl-CoA hydrolase:Predicted membrane-bound metal-dependent hydrolases:Glutaminase:Uncharacterized membrane protein, required for spore maturation in B.subtilis.:Arabinose efflux permease:Predicted permeases:Uncharacterized protein conserved in bacteria:Amino acid transport and metabolism:Nucleotide transport and metabolism:Carbohydrate transport and metabolism:Lipid transport and metabolism:Transcription:Posttranslational modification, protein turnover, chaperones:Alanine aspartate and glutamate metabolism:Arginine and proline metabolism:Phenylalanine tyrosine and tryptophan biosynthesis:D-Glutamine and D-glutamate metabolism:Glutathione metabolism:Peptidoglycan biosynthesis:Nitrogen metabolism:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:General function prediction only:Function unknown:TIGR00452:rarD:matE:araaP:2A78:aroQ:mviN:Gln_ase:Defense mechanisms:Unknown substrate:Transport and binding proteins:Amino acids and amines:Energy metabolism:Metabolism:Metabolism:Global:Glycan Biosynthesis and Metabolism:Metabolism of Other Amino Acids:Amino Acid Metabolism:Information storage and processing:Energy Metabolism:Cellular processes and signaling:Metabolism:Poorly characterized:Aromatic amino acid family:Amino acid biosynthesis:General:Enzymes of unknown specificity:Unknown function:Other:Amino acids, peptides and amines" 378 "Predicted glutamine amidotransferase:Predicted Zn-dependent proteases and their inactivated homologs:Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily):Glutathione S-transferase:Nucleoside phosphorylase:ABC-type amino acid transport/signal transduction systems, periplasmic component/domain:Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases):Putative threonine efflux protein:Predicted Rossmann fold nucleotide-binding protein:Acetyltransferases, including N-acetylases of ribosomal proteins:Uncharacterized conserved protein, contains double-stranded beta-helix domain:FOG: GGDEF domain:ABC-type uncharacterized transport system, auxiliary component:Metal-dependent hydrolase:Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain:Amino acid transport and metabolism:Nucleotide transport and metabolism:Lipid transport and metabolism:Translation, ribosomal structure and biogenesis:Posttranslational modification, protein turnover, chaperones:Purine metabolism:Cysteine and methionine metabolism:Metabolic pathways:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:Function unknown:Signal transduction mechanisms:GGDEF:AMP-nucleosdse:Nucleotide Metabolism:Metabolism:Poorly characterized:Metabolism:Cellular processes and signaling:Information storage and processing:Other:Signal transduction:Metabolism:Global:Amino Acid Metabolism" 379 "4-aminobutyrate aminotransferase and related aminotransferases:Selenocysteine lyase:Membrane-fusion protein:Non-ribosomal peptide synthetase modules and related proteins:Uncharacterized conserved protein:Zn-dependent dipeptidase, microsomal dipeptidase homolog:Predicted thioesterase involved in non-ribosomal peptide biosynthesis:Uncharacterized protein conserved in bacteria:Lysine/ornithine N-monooxygenase:ABC-type siderophore export system, fused ATPase and permease components:Amino acid transport and metabolism:Cell wall/membrane/envelope biogenesis:Inorganic ion transport and metabolism:Glycine serine and threonine metabolism:Metabolic pathways:Microbial metabolism in diverse environments:ABC transporters:Secondary metabolites biosynthesis, transport and catabolism:Function unknown:dat:cyc_pep_trnsptr:TAT_signal_seq:RND_mfp:AA-adenyl-dom:Unknown substrate:Amino Acid Metabolism:Environmental Information Processing:Membrane Transport:Global:Metabolism:Central intermediary metabolism:Other:Protein fate:Protein and peptide secretion and trafficking:Transport and binding proteins:Metabolism:Other:Cellular processes and signaling:Metabolism:Poorly characterized" 380 "Energy production and conversion:GTP cyclohydrolase I:Ni2+-binding GTPase involved in regulation of expression and maturation of urease and hydrogenase:ABC-type dipeptide transport system, periplasmic component:Urea amidohydrolase (urease) alpha subunit:Urease accessory protein UreH:Urea amidohydrolase (urease) gamma subunit:Urea amidohydrolase (urease) beta subunit:Cation/multidrug efflux pump:NAD-dependent aldehyde dehydrogenases:Hydrolases of the alpha/beta superfamily:Sortase and related acyltransferases:Predicted membrane protein:Dihydroneopterin aldolase:Uncharacterized conserved protein:Predicted phosphatase homologous to the C-terminal domain of histone macroH2A1:Protein related to penicillin acylase:Hydrogenase/urease accessory protein:Urease accessory protein UreE:Arginine/ornithine N-succinyltransferase beta subunit:Succinylarginine dihydrolase:ABC-type oligopeptide transport system, periplasmic component:ABC-type uncharacterized transport system, duplicated ATPase component:ABC-type uncharacterized transport system, permease component:ABC-type uncharacterized transport system, permease component:Putative Zn-dependent protease, contains TPR repeats:Ornithine/acetylornithine aminotransferase:Amino acid transport and metabolism:Coenzyme transport and metabolism:Transcription:Cell wall/membrane/envelope biogenesis:Posttranslational modification, protein turnover, chaperones:Purine metabolism:Lysine biosynthesis:Penicillin and cephalosporin biosynthesis:Arginine and proline metabolism:Phosphonate and phosphinate metabolism:Folate biosynthesis:Atrazine degradation:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:ABC transporters:General function prediction only:Function unknown:folE:ureG:urease_beta:urease_gam:TIGR00266:folB_dom:argD:OPT_sfam:urease_alph:arg_catab_astD:arg_catab_astB:arg_catab_AOST:Defense mechanisms:Information storage and processing:Folic acid:Biosynthesis of cofactors, prosthetic groups, and carriers:Conserved:Hypothetical proteins:Amino acids and amines:Energy metabolism:Nitrogen metabolism:Central intermediary metabolism:Cellular processes and signaling:Metabolism:Poorly characterized:Metabolism:Metabolism:Global:Membrane Transport:Environmental Information Processing:Xenobiotics Biodegradation and Metabolism:Biosynthesis of Other Secondary Metabolites:Metabolism of Cofactors and Vitamins:Metabolism of Other Amino Acids:Amino Acid Metabolism:Nucleotide Metabolism" 381 "Energy production and conversion:3-isopropylmalate dehydratase large subunit:3-isopropylmalate dehydratase small subunit:Isopropylmalate/homocitrate/citramalate synthases:Glucose-6-phosphate isomerase:Anaerobic dehydrogenases, typically selenocysteine-containing:Fe-S-cluster-containing hydrogenase components 1:Peroxiredoxin:Pyruvate kinase:Exoribonuclease R:rRNA methylases:Predicted esterase:Putative intracellular protease/amidase:Zn-dependent alcohol dehydrogenases, class III:Predicted ATPase related to phosphate starvation-inducible protein PhoH:Selenocysteine synthase [seryl-tRNASer selenium transferase]:Dioxygenases related to 2-nitropropane dioxygenase:Cytochrome b subunit of formate dehydrogenase:Predicted enzyme of the cupin superfamily:Predicted metal-dependent hydrolase:Glucose dehydrogenase:Amino acid transport and metabolism:Carbohydrate transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:Posttranslational modification, protein turnover, chaperones:Glycolysis / Gluconeogenesis:Pentose phosphate pathway:Fatty acid metabolism:Purine metabolism:Valine leucine and isoleucine biosynthesis:Tyrosine metabolism:Selenocompound metabolism:Starch and sucrose metabolism:Amino sugar and nucleotide sugar metabolism:Pyruvate metabolism:Chloroalkane and chloroalkene degradation:Naphthalene degradation:Glyoxylate and dicarboxylate metabolism:C5-Branched dibasic acid metabolism:Methane metabolism:Aminoacyl-tRNA biosynthesis:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:RNA degradation:General function prediction only:Signal transduction mechanisms:leuC:leuD:rRNA_methyl_3:3_prime_RNase:selA:leuA_yeast:pyruv_kin:PfpI:formate-DH-alph:FDH-beta:formate-DH-gamm:adh_III_F_hyde:fghA_ester_D:PQQ_membr_DH:Cellular processes:Carbohydrate Metabolism:Energy Metabolism:Lipid Metabolism:Nucleotide Metabolism:Amino Acid Metabolism:Metabolism of Other Amino Acids:Xenobiotics Biodegradation and Metabolism:Genetic Information Processing:Translation:Folding Sorting and Degradation:Global:Metabolism:Energy metabolism:Electron transport:Fermentation:Glycolysis/gluconeogenesis:Transcription:Degradation of RNA:Protein synthesis:tRNA aminoacylation:tRNA and rRNA base modification:Protein fate:Degradation of proteins, peptides, and glycopeptides:Metabolism:Detoxification:Amino acid biosynthesis:Pyruvate family:Information storage and processing:Cellular processes and signaling:Metabolism:Poorly characterized" 382 "Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases:Signal transduction histidine kinase:Methyl-accepting chemotaxis protein:Dipeptidyl aminopeptidases/acylaminoacyl-peptidases:Xanthine and CO dehydrogenases maturation factor, XdhC/CoxF family:Adenosine deaminase:Serine phosphatase RsbU, regulator of sigma subunit:Cation transport ATPase:Uncharacterized protein conserved in bacteria:Uncharacterized conserved protein:Uncharacterized conserved protein:Predicted periplasmic ligand-binding sensor domain:Uncharacterized protein conserved in bacteria:L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily:Amino acid transport and metabolism:Nucleotide transport and metabolism:Transcription:Cell wall/membrane/envelope biogenesis:Cell motility:Posttranslational modification, protein turnover, chaperones:Inorganic ion transport and metabolism:Two-component system:Bacterial chemotaxis:General function prediction only:Function unknown:Signal transduction mechanisms:sensory_box:ogt:ATPase-IB_hvy:xanthine_xdhC:Regulatory functions:Other:Purines, pyrimidines, nucleosides, and nucleotides:Cell Motility:Cellular Processes:Signal Transduction:Poorly characterized:Metabolism:Cellular processes and signaling:Information storage and processing:DNA replication, recombination, and repair:Environmental Information Processing:DNA metabolism:Small molecule interactions" 383 "Acetylglutamate kinase:Small-conductance mechanosensitive channel:High-affinity Fe2+/Pb2+ permease:Phosphohistidine phosphatase SixA:Predicted restriction endonuclease:Amino acid transport and metabolism:Cell wall/membrane/envelope biogenesis:Inorganic ion transport and metabolism:Arginine and proline metabolism:Metabolic pathways:Biosynthesis of secondary metabolites:Signal transduction mechanisms:sixA:N-Ac-Glu-synth:Defense mechanisms:Glutamate family:Amino Acid Metabolism:Global:Metabolism:Regulatory functions:Protein interactions:Amino acid biosynthesis:Metabolism:Cellular processes and signaling:Metabolism" 384 "Energy production and conversion:Putative translation factor (SUA5):Acetyltransferase (isoleucine patch superfamily):Histidinol phosphatase and related phosphatases:Thiamine monophosphate synthase:Aspartate/tyrosine/aromatic aminotransferase:Glutathione S-transferase:Signal transduction histidine kinase:Uracil DNA glycosylase:Exonuclease III:Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain:Aspartate 1-decarboxylase:Enoyl-CoA hydratase/carnithine racemase:Uncharacterized protein conserved in bacteria:Transcriptional regulators of sugar metabolism:Nicotinic acid phosphoribosyltransferase:Predicted esterase of the alpha-beta hydrolase superfamily:Threonine aldolase:Uncharacterized conserved protein:Membrane-bound lytic murein transglycosylase B:Uncharacterized protein conserved in bacteria:Predicted membrane protein:Type IV secretory pathway, VirJ component:Predicted enolase-phosphatase:Amino acid transport and metabolism:Carbohydrate transport and metabolism:Coenzyme transport and metabolism:Lipid transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:Replication, recombination and repair:Cell wall/membrane/envelope biogenesis:Posttranslational modification, protein turnover, chaperones:Fatty acid metabolism:Glycine serine and threonine metabolism:Cysteine and methionine metabolism:Valine leucine and isoleucine degradation:Geraniol degradation:Lysine degradation:Benzoate degradation:Tryptophan metabolism:beta-Alanine metabolism:Glutathione metabolism:Lipopolysaccharide biosynthesis:Aminobenzoate degradation:Propanoate metabolism:Butanoate metabolism:Nicotinate and nicotinamide metabolism:Pantothenate and CoA biosynthesis:Porphyrin and chlorophyll metabolism:Limonene and pinene degradation:Caprolactam degradation:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:Base excision repair:General function prediction only:Function unknown:Signal transduction mechanisms:exoDNase_III:panD:mutt:ung:NAPRTase:Histidinol-ppas:enolase-ppase:CXXU_selWTH:MltB_2:Intracellular trafficking, secretion, and vesicular transport:Metabolism:Metabolism of Terpenoids and Polyketides:Metabolism of Cofactors and Vitamins:Glycan Biosynthesis and Metabolism:Metabolism of Other Amino Acids:Amino Acid Metabolism:Lipid Metabolism:Pyridine nucleotides:Carbohydrate Metabolism:Cell envelope:Biosynthesis and degradation of murein sacculus and peptidoglycan:Information storage and processing:Cellular processes and signaling:Metabolism:Poorly characterized:Pantothenate and coenzyme A:Biosynthesis of cofactors, prosthetic groups, and carriers:DNA replication, recombination, and repair:DNA metabolism:Sulfur metabolism:Central intermediary metabolism:Metabolism:Global:Replication and Repair:Genetic Information Processing:Xenobiotics Biodegradation and Metabolism" 385 "Glycosyltransferase:Adenylylsulfate kinase and related kinases:UDP-glucose 4-epimerase:Type II secretory pathway, component PulD:Beta-lactamase class C and other penicillin binding proteins:Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain:AraC-type DNA-binding domain-containing proteins:P pilus assembly protein, chaperone PapD:P pilus assembly protein, pilin FimA:ABC-type uncharacterized transport system, ATPase component:Transcription:Cell wall/membrane/envelope biogenesis:Cell motility:Inorganic ion transport and metabolism:Galactose metabolism:Purine metabolism:Selenocompound metabolism:Amino sugar and nucleotide sugar metabolism:Sulfur metabolism:Metabolic pathways:Microbial metabolism in diverse environments:ABC transporters:Two-component system:Bacterial secretion system:General function prediction only:Signal transduction mechanisms:apsK:galE:Intracellular trafficking, secretion, and vesicular transport:Defense mechanisms:Metabolism:Global:Signal Transduction:Membrane Transport:Environmental Information Processing:Metabolism of Other Amino Acids:Nucleotide Metabolism:Energy Metabolism:Carbohydrate Metabolism:Central intermediary metabolism:Sulfur metabolism:Energy metabolism:Sugars:Information storage and processing:Cellular processes and signaling:Metabolism:Poorly characterized:Metabolism" 386 "Energy production and conversion:Uroporphyrinogen-III methylase:Anaerobic dehydrogenases, typically selenocysteine-containing:ABC-type branched-chain amino acid transport systems, ATPase component:Putative intracellular protease/amidase:NAD(P)H-nitrite reductase:Outer membrane protein:NADH:flavin oxidoreductases, Old Yellow Enzyme family:Sulfite oxidase and related enzymes:Ferredoxin subunits of nitrite reductase and ring-hydroxylating dioxygenases:Arabinose efflux permease:TRAP-type C4-dicarboxylate transport system, small permease component:Predicted double-glycine peptidase:Response regulator with putative antiterminator output domain:Thiosulfate reductase cytochrome B subunit (membrane anchoring protein):Uncharacterized ABC-type transport system, ATPase component:Predicted RNA polymerase sigma factor containing a TPR repeat domain:Amino acid transport and metabolism:Carbohydrate transport and metabolism:Coenzyme transport and metabolism:Transcription:Cell wall/membrane/envelope biogenesis:Inorganic ion transport and metabolism:Porphyrin and chlorophyll metabolism:Nitrogen metabolism:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:ABC transporters:Two-component system:RNA polymerase:General function prediction only:Signal transduction mechanisms:cobA_cysG_Cterm:outer_NodT:nitri_red_nirB:nirD_assim_sml:sigma70-ECF:urea_trans_UrtE:urea_trans_UrtD:Intracellular trafficking, secretion, and vesicular transport:Poorly characterized:Metabolism:Cellular processes and signaling:Information storage and processing:Heme, porphyrin, and cobalamin:Biosynthesis of cofactors, prosthetic groups, and carriers:Porins:Amino acids, peptides and amines:Transport and binding proteins:Nitrogen metabolism:Central intermediary metabolism:Metabolism:Metabolism:Global:Signal Transduction:Membrane Transport:Environmental Information Processing:Transcription:Genetic Information Processing:Metabolism of Cofactors and Vitamins:Energy Metabolism" 387 "Acetyltransferases:Pseudouridylate synthases, 23S RNA-specific:Thiamine monophosphate kinase:Signal transduction histidine kinase:Predicted unusual protein kinase:Uncharacterized membrane protein (homolog of Drosophila rhomboid):MoxR-like ATPases:ABC-type multidrug transport system, permease component:Biopolymer transport protein:Pyridoxal phosphate biosynthesis protein:Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases):Recombinational DNA repair protein (RecF pathway):Uncharacterized protein conserved in bacteria:Multidrug resistance efflux pump:Uncharacterized conserved protein (some members contain a von Willebrand factor type A (vWA) domain):Acyl-CoA thioesterase:Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain:FOG: HPt domain:Pyridoxal/pyridoxine/pyridoxamine kinase:Lysophospholipase:Uncharacterized protein containing a von Willebrand factor type A (vWA) domain:Uncharacterized small membrane protein:Uncharacterized protein conserved in bacteria:Predicted aspartyl protease:ABC-type phosphate/phosphonate transport system, permease component:Uncharacterized conserved protein:Predicted soluble lytic transglycosylase fused to an ABC-type amino acid-binding protein:Uncharacterized conserved protein:Coenzyme transport and metabolism:Lipid transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:Replication, recombination and repair:Cell wall/membrane/envelope biogenesis:Inorganic ion transport and metabolism:Ubiquinone and other terpenoid-quinone biosynthesis:Thiamine metabolism:Vitamin B6 metabolism:Metabolic pathways:Biosynthesis of secondary metabolites:ABC transporters:Homologous recombination:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:Function unknown:Signal transduction mechanisms:TIGR00046:pdxJ:reco:pyridox_kin:PhnE:thiL:rimI:UbiB:clan_AA_DTGA:ribofla_fusion:Intracellular trafficking, secretion, and vesicular transport:Defense mechanisms:Pyridoxine:Menaquinone and ubiquinone:Biosynthesis of cofactors, prosthetic groups, and carriers:Anions:Transport and binding proteins:Degradation of proteins, peptides, and glycopeptides:Protein fate:tRNA and rRNA base modification:Ribosomal proteins: synthesis and modification:Protein synthesis:DNA replication, recombination, and repair:DNA metabolism:Metabolism:Metabolism:Global:Membrane Transport:Environmental Information Processing:Replication and Repair:Genetic Information Processing:Metabolism of Cofactors and Vitamins:Poorly characterized:Metabolism:Cellular processes and signaling:Information storage and processing:Thiamine" 388 "Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases:Predicted integral membrane protein:Chemotaxis protein histidine kinase and related kinases:Chemotaxis signal transduction protein:Methyl-accepting chemotaxis protein:Cation/multidrug efflux pump:Membrane-fusion protein:Methylase of chemotaxis methyl-accepting proteins:FOG: GGDEF domain:Chemotaxis response regulator containing a CheY-like receiver domain and a methylesterase domain:Tfp pilus assembly protein, pilus retraction ATPase PilT:Arabinose efflux permease:Outer membrane protein and related peptidoglycan-associated (lipo)proteins:Putative arginyl-tRNA:protein arginylyltransferase:Tfp pilus assembly protein FimV:Predicted deacetylase:Phospholipase/lecithinase/hemolysin:Signal transduction histidine kinase regulating citrate/malate metabolism:Response regulator containing a CheY-like receiver domain and a GGDEF domain:Bacteriophytochrome (light-regulated signal transduction histidine kinase):Dipeptidase:Amino acid transport and metabolism:Carbohydrate transport and metabolism:Lipid transport and metabolism:Translation, ribosomal structure and biogenesis:Cell wall/membrane/envelope biogenesis:Cell motility:Posttranslational modification, protein turnover, chaperones:Arginine and proline metabolism:Phenylalanine metabolism:Tryptophan metabolism:Cyanoamino acid metabolism:Aminobenzoate degradation:Styrene degradation:Microbial metabolism in diverse environments:Two-component system:General function prediction only:Function unknown:Signal transduction mechanisms:GGDEF:TIGR00374:pilT_fam:RND_mfp:FimV_Cterm:Intracellular trafficking, secretion, and vesicular transport:Defense mechanisms:Amino Acid Metabolism:Conserved:Signal transduction:Other:Information storage and processing:Cellular processes and signaling:Metabolism:Poorly characterized:Metabolism:Chemotaxis and motility:Cellular processes:Unknown substrate:Transport and binding proteins:Metabolism:Global:Signal Transduction:Environmental Information Processing:Xenobiotics Biodegradation and Metabolism:Metabolism of Other Amino Acids:Hypothetical proteins" 389 "Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II:Pyrroline-5-carboxylate reductase:Serine/threonine protein kinase:ATPases with chaperone activity, ATP-binding subunit:Organic radical activating enzymes:Catalase:Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases):Superfamily I DNA and RNA helicases and helicase subunits:N-acetylglucosamine-1-phosphate uridyltransferase (contains nucleotidyltransferase and I-patch acetyltransferase domains):Uncharacterized conserved protein:N-acetylglutamate synthase (N-acetylornithine aminotransferase):Outer membrane receptor proteins, mostly Fe transport:3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases:Putative NADP-dependent oxidoreductases:NTP pyrophosphohydrolases containing a Zn-finger, probably nucleic-acid-binding:O-acetylhomoserine sulfhydrylase:Gamma-glutamylcysteine synthetase:Uncharacterized iron-regulated membrane protein:Gluconolactonase:Predicted periplasmic lipoprotein:Amino acid transport and metabolism:Carbohydrate transport and metabolism:Coenzyme transport and metabolism:Lipid transport and metabolism:Transcription:Replication, recombination and repair:Cell wall/membrane/envelope biogenesis:Posttranslational modification, protein turnover, chaperones:Inorganic ion transport and metabolism:Fructose and mannose metabolism:Fatty acid metabolism:Cysteine and methionine metabolism:Arginine and proline metabolism:Bisphenol degradation:Glutathione metabolism:Amino sugar and nucleotide sugar metabolism:Chloroalkane and chloroalkene degradation:Butanoate metabolism:Nicotinate and nicotinamide metabolism:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:Function unknown:Signal transduction mechanisms:proC:ArgJ:glmU:OAH_OAS_sulfhy:glu_cys_ligase:TonB-copper:Information storage and processing:Carbohydrate Metabolism:Lipid Metabolism:Amino Acid Metabolism:Metabolism of Other Amino Acids:Metabolism of Cofactors and Vitamins:Xenobiotics Biodegradation and Metabolism:Global:Metabolism:Central intermediary metabolism:Amino sugars:Transport and binding proteins:Porins:Amino acid biosynthesis:Glutamate family:Serine family:Biosynthesis of cofactors, prosthetic groups, and carriers:Glutathione and analogs:Metabolism:Cellular processes and signaling:Metabolism:Poorly characterized" 390 "Uroporphyrinogen-III methylase:Putative translation factor (SUA5):Aminopeptidase N:Thioredoxin reductase:Predicted phosphatases:Anthranilate phosphoribosyltransferase:Uncharacterized conserved protein:Uncharacterized conserved protein involved in intracellular sulfur reduction:Uncharacterized protein conserved in bacteria:Uncharacterized conserved protein involved in oxidation of intracellular sulfur:ATPase related to the helicase subunit of the Holliday junction resolvase:Leu/Phe-tRNA-protein transferase:Outer membrane lipoprotein-sorting protein:Outer membrane protein and related peptidoglycan-associated (lipo)proteins:Dissimilatory sulfite reductase (desulfoviridin), gamma subunit:Uncharacterized protein involved in the oxidation of intracellular sulfur:Putative arginyl-tRNA:protein arginylyltransferase:Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain:Amino acid transport and metabolism:Coenzyme transport and metabolism:Translation, ribosomal structure and biogenesis:Replication, recombination and repair:Cell wall/membrane/envelope biogenesis:Posttranslational modification, protein turnover, chaperones:Inorganic ion transport and metabolism:Pyrimidine metabolism:Glutathione metabolism:Glyoxylate and dicarboxylate metabolism:Porphyrin and chlorophyll metabolism:Metabolic pathways:Biosynthesis of secondary metabolites:Sulfur relay system:General function prediction only:Function unknown:Signal transduction mechanisms:TIGR00057:sensory_box:lolA:aat:TRX_reduct:PGP_bact:cobA_cysG_Cterm:pepN_proteo:sulf_tusC_dsrF:sulf_tusB_dsrH:sulf_tusD_dsrE:dsrC_tusE_dsvC:Degradation of proteins, peptides, and glycopeptides:Carbohydrate Metabolism:Nucleotide Metabolism:Metabolism of Other Amino Acids:Metabolism of Cofactors and Vitamins:Genetic Information Processing:Folding Sorting and Degradation:Global:Metabolism:Energy metabolism:Electron transport:Sugars:Regulatory functions:Small molecule interactions:Protein synthesis:tRNA and rRNA base modification:Protein fate:Protein and peptide secretion and trafficking:Metabolism:Unknown function:General:Biosynthesis of cofactors, prosthetic groups, and carriers:Heme, porphyrin, and cobalamin:Information storage and processing:Cellular processes and signaling:Metabolism:Poorly characterized" 391 "Non-ribosomal peptide synthetase modules and related proteins:Peptide arylation enzymes:ABC-type multidrug transport system, ATPase and permease components:Isochorismate synthase:Chorismate mutase:Uncharacterized iron-regulated membrane protein:Predicted thioesterase involved in non-ribosomal peptide biosynthesis:Oxidoreductase (NAD-binding), involved in siderophore biosynthesis:Outer membrane receptor for ferric coprogen and ferric-rhodotorulic acid:Amino acid transport and metabolism:Coenzyme transport and metabolism:Inorganic ion transport and metabolism:Ubiquinone and other terpenoid-quinone biosynthesis:Biosynthesis of siderophore group nonribosomal peptides:Metabolic pathways:Biosynthesis of secondary metabolites:ABC transporters:Secondary metabolites biosynthesis, transport and catabolism:Function unknown:isochor_syn:AA-adenyl-dom:thiaz-red:TonB-siderophor:CM-like:sider_RhtX_FptX:Defense mechanisms:Poorly characterized:Metabolism of Cofactors and Vitamins:Metabolism of Terpenoids and Polyketides:Environmental Information Processing:Membrane Transport:Global:Metabolism:Transport and binding proteins:Cations and iron carrying compounds:Porins:Biosynthesis of cofactors, prosthetic groups, and carriers:Menaquinone and ubiquinone:Cellular processes and signaling:Metabolism:Metabolism" 392 "Membrane-fusion protein:Outer membrane protein:ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain:P pilus assembly protein, chaperone PapD:Poly(3-hydroxyalkanoate) synthetase:Signal transduction histidine kinase, nitrogen specific:Flp pilus assembly protein, ATPase CpaF:Flp pilus assembly protein, ATPase CpaE:Flp pilus assembly protein TadD, contains TPR repeats:Uncharacterized secreted protein:Lipid transport and metabolism:Cell wall/membrane/envelope biogenesis:Cell motility:Butanoate metabolism:ABC transporters:Function unknown:Signal transduction mechanisms:sensory_box:PHA_synth_II:type_I_sec_LssB:Intracellular trafficking, secretion, and vesicular transport:Defense mechanisms:Poorly characterized:Carbohydrate Metabolism:Environmental Information Processing:Membrane Transport:Fatty acid and phospholipid metabolism:Biosynthesis:Regulatory functions:Small molecule interactions:Cellular processes:Pathogenesis:Cellular processes and signaling:Metabolism:Metabolism" 393 "Molecular chaperone (small heat shock protein):Co-chaperonin GroES (HSP10):Dihydrodipicolinate reductase:Predicted enzyme with a TIM-barrel fold:Molecular chaperone, HSP90 family:Zn-dependent oligopeptidases:Pyrroline-5-carboxylate reductase:Dienelactone hydrolase and related enzymes:Molecular chaperone:Chaperonin GroEL (HSP60 family):ATP-dependent Zn proteases:ATP-dependent Lon protease, bacterial type:DnaJ-class molecular chaperone with C-terminal Zn finger domain:Zn-dependent protease with chaperone function:ATPases with chaperone activity, ATP-binding subunit:Molecular chaperone GrpE (heat shock protein):ATP-dependent protease HslVU (ClpYQ), ATPase subunit:Protein affecting phage T7 exclusion by the F plasmid:Thioredoxin domain-containing protein:Uncharacterized protein conserved in bacteria:ATP-dependent protease HslVU (ClpYQ), peptidase subunit:Amino acid transport and metabolism:Posttranslational modification, protein turnover, chaperones:Lysine biosynthesis:Arginine and proline metabolism:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:RNA degradation:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:Function unknown:dapB:TIGR00044:proC:hslU:lon:thioredoxin:FtsH_fam:GroEL:DnaJ_bact:prok_dnaK:chaperone_ClpB:ATP_dep_HslV:Amino acid biosynthesis:Amino Acid Metabolism:Genetic Information Processing:Folding Sorting and Degradation:Global:Metabolism:Energy metabolism:Electron transport:Protein fate:Protein folding and stabilization:Degradation of proteins, peptides, and glycopeptides:Unknown function:Enzymes of unknown specificity:Metabolism:Aspartate family:Glutamate family:Cellular processes and signaling:Metabolism:Poorly characterized" 394 "Energy production and conversion:Adenosylmethionine-8-amino-7-oxononanoate aminotransferase:Nucleoside-diphosphate-sugar epimerases:Amino acid transporters:Transcriptional regulator:Methyl-accepting chemotaxis protein:Ferredoxin:Triphosphoribosyl-dephospho-CoA synthetase:Predicted acyl-CoA transferases/carnitine dehydratase:Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain:Arabinose efflux permease:L-aminopeptidase/D-esterase:Uncharacterized conserved protein:Predicted enzyme of the cupin superfamily:Carbohydrate-selective porin:Uncharacterized conserved protein:Uncharacterized protein conserved in bacteria:Outer membrane receptor for monomeric catechols:Amino acid transport and metabolism:Carbohydrate transport and metabolism:Coenzyme transport and metabolism:Transcription:Cell wall/membrane/envelope biogenesis:Cell motility:Inorganic ion transport and metabolism:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:Function unknown:Signal transduction mechanisms:TonB-siderophor:malonate_delta:malonate_mdcB:malonate_mdcG:Information storage and processing:Other:Biosynthesis of cofactors, prosthetic groups, and carriers:Porins:Transport and binding proteins:Other:Energy metabolism:Metabolism:Poorly characterized:Cellular processes and signaling" 395 "Energy production and conversion:Glutamyl- and glutaminyl-tRNA synthetases:Riboflavin synthase beta-chain:Chorismate synthase:Predicted translation initiation factor 2B subunit, eIF-2B alpha/beta/delta family:Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), A subunit:Threonyl-tRNA synthetase:Predicted tRNA(5-methylaminomethyl-2-thiouridylate) methyltransferase, contains the PP-loop ATPase domain:Predicted Fe-S-cluster redox enzyme:Deoxyxylulose-5-phosphate synthase:Na+-transporting NADH:ubiquinone oxidoreductase, subunit NqrA:Na+-transporting NADH:ubiquinone oxidoreductase, subunit NqrB:Uncharacterized protein involved in purine metabolism:Amino acid transport and metabolism:Coenzyme transport and metabolism:Lipid transport and metabolism:Translation, ribosomal structure and biogenesis:Replication, recombination and repair:Cysteine and methionine metabolism:Phenylalanine tyrosine and tryptophan biosynthesis:Riboflavin metabolism:Porphyrin and chlorophyll metabolism:Terpenoid backbone biosynthesis:Aminoacyl-tRNA biosynthesis:Metabolic pathways:Biosynthesis of secondary metabolites:Sulfur relay system:General function prediction only:aroC:TIGR00048:lumazine-synth:dxs:thrS:trmU:gltX_bact:salvage_mtnA:gyrA:nqrA:nqrB:Information storage and processing:Metabolism:Poorly characterized:Metabolism:Metabolism:Global:Folding Sorting and Degradation:Translation:Genetic Information Processing:Metabolism of Terpenoids and Polyketides:Metabolism of Cofactors and Vitamins:Amino Acid Metabolism:DNA metabolism:DNA replication, recombination, and repair:Protein synthesis:tRNA aminoacylation:tRNA and rRNA base modification:Transport and binding proteins:Cations and iron carrying compounds:Amino acid biosynthesis:Aromatic amino acid family:Aspartate family:Biosynthesis of cofactors, prosthetic groups, and carriers:Riboflavin, FMN, and FAD:Thiamine" 396 "Energy production and conversion:Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase:NAD-dependent DNA ligase (contains BRCT domain type II):Cytosine deaminase and related metal-dependent hydrolases:Aspartate/tyrosine/aromatic aminotransferase:ATPase involved in DNA replication:Uncharacterized membrane-associated protein:7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase:Primosomal protein N' (replication factor Y) - superfamily II helicase:4-diphosphocytidyl-2-methyl-D-erithritol synthase:Uncharacterized conserved protein:Protein related to penicillin acylase:UTP:GlnB (protein PII) uridylyltransferase:Predicted NADH:ubiquinone oxidoreductase, subunit RnfB:Septum formation initiator:ABC-type arginine transport system, permease component:Predicted NADH:ubiquinone oxidoreductase, subunit RnfD:Predicted NADH:ubiquinone oxidoreductase, subunit RnfG:Predicted NADH:ubiquinone oxidoreductase, subunit RnfE:Cell cycle control, cell division, chromosome partitioning:Amino acid transport and metabolism:Nucleotide transport and metabolism:Coenzyme transport and metabolism:Lipid transport and metabolism:Replication, recombination and repair:Posttranslational modification, protein turnover, chaperones:Purine metabolism:Pyrimidine metabolism:Lysine biosynthesis:Arginine and proline metabolism:Folate biosynthesis:Terpenoid backbone biosynthesis:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:ABC transporters:Two-component system:DNA replication:Base excision repair:Nucleotide excision repair:Mismatch repair:Homologous recombination:General function prediction only:Function unknown:ispD:dnlj:priA:holB:TIGR00702:folK:UTase_glnD:HEQRo_perm_3TM:rnfB:rnfD:rnfG:rnfE:pabC_Proteo:DapC_gpp:Membrane Transport:Environmental Information Processing:Replication and Repair:Genetic Information Processing:Metabolism of Terpenoids and Polyketides:Metabolism of Cofactors and Vitamins:Amino Acid Metabolism:Nucleotide Metabolism:Energy metabolism:Electron transport:Regulatory functions:Protein interactions:DNA metabolism:DNA replication, recombination, and repair:Transport and binding proteins:Amino acids, peptides and amines:Hypothetical proteins:Conserved:Biosynthesis of cofactors, prosthetic groups, and carriers:Other:Folic acid:Information storage and processing:Cellular processes and signaling:Metabolism:Poorly characterized:Metabolism:Global:Signal Transduction:Metabolism" 397 "Energy production and conversion:Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase]:Aspartate/tyrosine/aromatic aminotransferase:FOG: CBS domain:Transcriptional regulator:Glutathione S-transferase:Uncharacterized enzymes related to aldose 1-epimerase:Predicted thioesterase:ABC-type amino acid transport/signal transduction systems, periplasmic component/domain:NAD-dependent aldehyde dehydrogenases:Long-chain acyl-CoA synthetases (AMP-forming):Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases):ABC-type antimicrobial peptide transport system, ATPase component:3-hydroxyacyl-CoA dehydrogenase:Alcohol dehydrogenase, class IV:Transcriptional regulators:N-acetylglucosamine-6-phosphate deacetylase:Acyl-CoA dehydrogenases:Uncharacterized protein, possibly involved in aromatic compounds catabolism:Transcriptional regulators:Predicted enzyme related to lactoylglutathione lyase:Xanthine dehydrogenase, molybdopterin-binding subunit B:Amino acid transport and metabolism:Nucleotide transport and metabolism:Carbohydrate transport and metabolism:Coenzyme transport and metabolism:Lipid transport and metabolism:Transcription:Posttranslational modification, protein turnover, chaperones:Glycolysis / Gluconeogenesis:Pentose and glucuronate interconversions:Ascorbate and aldarate metabolism:Fatty acid metabolism:Purine metabolism:Valine leucine and isoleucine degradation:Valine leucine and isoleucine biosynthesis:Lysine degradation:Arginine and proline metabolism:Histidine metabolism:Tryptophan metabolism:beta-Alanine metabolism:Amino sugar and nucleotide sugar metabolism:Glycerolipid metabolism:Pyruvate metabolism:Chloroalkane and chloroalkene degradation:Propanoate metabolism:Butanoate metabolism:C5-Branched dibasic acid metabolism:Pantothenate and CoA biosynthesis:Limonene and pinene degradation:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:ABC transporters:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:Signal transduction mechanisms:nagA:unchar_dom_1:xanthine_xdhB:Defense mechanisms:Central intermediary metabolism:Carbohydrate Metabolism:Lipid Metabolism:Nucleotide Metabolism:Amino Acid Metabolism:Metabolism of Other Amino Acids:Metabolism of Cofactors and Vitamins:Metabolism of Terpenoids and Polyketides:Xenobiotics Biodegradation and Metabolism:Environmental Information Processing:Membrane Transport:Global:Metabolism:Metabolism:Amino sugars:Purines, pyrimidines, nucleosides, and nucleotides:Other:Information storage and processing:Cellular processes and signaling:Metabolism:Poorly characterized" 398 "Thymidylate synthase:Nucleoside-diphosphate-sugar epimerases:Leucyl-tRNA synthetase:Phosphoserine phosphatase:Predicted dehydrogenase:3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase:3-dehydroquinate dehydratase II:dTDP-4-dehydrorhamnose reductase:Hemolysins and related proteins containing CBS domains:Uncharacterized protein conserved in bacteria:Acyl-CoA thioesterase:Uncharacterized protein conserved in bacteria:Glycine cleavage system regulatory protein:Septum formation inhibitor-activating ATPase:Intracellular septation protein A:Uncharacterized protein conserved in bacteria:Na+/serine symporter:Uncharacterized protein conserved in archaea:Cell cycle control, cell division, chromosome partitioning:Amino acid transport and metabolism:Nucleotide transport and metabolism:Carbohydrate transport and metabolism:Lipid transport and metabolism:Translation, ribosomal structure and biogenesis:Cell wall/membrane/envelope biogenesis:Posttranslational modification, protein turnover, chaperones:Galactose metabolism:Pyrimidine metabolism:Valine leucine and isoleucine biosynthesis:Phenylalanine tyrosine and tryptophan biosynthesis:Amino sugar and nucleotide sugar metabolism:Streptomycin biosynthesis:Polyketide sugar unit biosynthesis:Pyruvate metabolism:One carbon pool by folate:Aminoacyl-tRNA biosynthesis:Biosynthesis of unsaturated fatty acids:Metabolic pathways:Biosynthesis of secondary metabolites:General function prediction only:Function unknown:aroFGH:tesB:leuS_bact:ispZ:aroQ:mal_quin_oxido:HAD-SF-IB:minD_bact:tol_pal_ybgF:thym_sym:Metabolism:Poorly characterized:Energy metabolism:Metabolism:Global:Metabolism:Translation:Genetic Information Processing:Biosynthesis of Other Secondary Metabolites:Metabolism of Terpenoids and Polyketides:Metabolism of Cofactors and Vitamins:Amino Acid Metabolism:Nucleotide Metabolism:Lipid Metabolism:TCA cycle:Carbohydrate Metabolism:Fatty acid and phospholipid metabolism:Biosynthesis:Purines, pyrimidines, nucleosides, and nucleotides:2'-Deoxyribonucleotide metabolism:Protein synthesis:tRNA aminoacylation:Cellular processes:Cell division:Unknown function:Enzymes of unknown specificity:Amino acid biosynthesis:Aromatic amino acid family:Information storage and processing:Cellular processes and signaling" 399 "Energy production and conversion:Predicted Fe-S oxidoreductases:Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily):Uncharacterized homolog of gamma-carboxymuconolactone decarboxylase subunit:Predicted nucleoside-diphosphate-sugar epimerases:Aconitase A:ABC-type proline/glycine betaine transport systems, ATPase components:ABC-type proline/glycine betaine transport systems, permease component:Metal-dependent hydrolases of the beta-lactamase superfamily I:Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily:Dipeptidyl aminopeptidases/acylaminoacyl-peptidases:Periplasmic glycine betaine/choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein):ABC-type proline/glycine betaine transport system, ATPase component:ABC-type proline/glycine betaine transport system, permease component:Pyrroloquinoline quinone (Coenzyme PQQ) biosynthesis protein C:Amino acid transport and metabolism:Carbohydrate transport and metabolism:Coenzyme transport and metabolism:Cell wall/membrane/envelope biogenesis:Citrate cycle (TCA cycle):Benzoate degradation:Glyoxylate and dicarboxylate metabolism:Carbon fixation pathways in prokaryotes:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:ABC transporters:General function prediction only:Function unknown:proV:aconitase_1:PQQ_syn_pqqA:PQQ_syn_pqqB:PQQ_syn_pqqE:PQQ_syn_pqqC:decarb_PcaC:protocat_pcaD:ABC_choXWV_ATP:ABC_choXWV_perm:PQQ_PqqD:Metabolism:Cellular processes and signaling:Other:Biosynthesis of cofactors, prosthetic groups, and carriers:Amino acids, peptides and amines:Transport and binding proteins:Other:TCA cycle:Energy metabolism:Metabolism:Metabolism:Global:Membrane Transport:Environmental Information Processing:Xenobiotics Biodegradation and Metabolism:Energy Metabolism:Poorly characterized:Carbohydrate Metabolism" 400 "Transcriptional regulator:Parvulin-like peptidyl-prolyl isomerase:Periplasmic protein TonB, links inner and outer membranes:Type II secretory pathway, component PulD:Type II secretory pathway, component PulF:Type II secretory pathway, pseudopilin PulG:Type II secretory pathway, ATPase PulE/Tfp pilus assembly pathway, ATPase PilB:Type II secretory pathway, component PulM:Type II secretory pathway, component PulK:Transcription:Cell wall/membrane/envelope biogenesis:Cell motility:Posttranslational modification, protein turnover, chaperones:Bacterial secretion system:tonB_Cterm:gspI:typeII_sec_gspG:adhes_NPXG:GspF:type_II_gspD:type_II_gspE:Intracellular trafficking, secretion, and vesicular transport:Information storage and processing:Membrane Transport:Protein fate:Protein and peptide secretion and trafficking:Transport and binding proteins:Cations and iron carrying compounds:Cellular processes:Pathogenesis:Environmental Information Processing:Cellular processes and signaling" 401 "Energy production and conversion:Serine-pyruvate aminotransferase/archaeal aspartate aminotransferase:Shikimate 5-dehydrogenase:Acetyl-CoA acetyltransferase:Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases:Transcriptional regulator:Signal transduction histidine kinase:Predicted membrane protein:Transcriptional regulator:Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL homologs:DNA uptake protein and related DNA-binding proteins:Multidrug resistance efflux pump:Uncharacterized protein involved in propionate catabolism:Na+/melibiose symporter and related transporters:Nitrate/nitrite transporter:Arabinose efflux permease:4-hydroxyphenylpyruvate dioxygenase and related hemolysins:P pilus assembly protein, porin PapC:Uncharacterized conserved protein:Uncharacterized conserved protein:Amino acid transport and metabolism:Carbohydrate transport and metabolism:Lipid transport and metabolism:Transcription:Replication, recombination and repair:Cell motility:Inorganic ion transport and metabolism:Fatty acid metabolism:Ubiquinone and other terpenoid-quinone biosynthesis:Valine leucine and isoleucine degradation:Geraniol degradation:Tyrosine metabolism:Phenylalanine metabolism:Benzoate degradation:Phenylalanine tyrosine and tryptophan biosynthesis:Phosphonate and phosphinate metabolism:alpha-Linolenic acid metabolism:Aminoacyl-tRNA biosynthesis:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:Two-component system:General function prediction only:Function unknown:Signal transduction mechanisms:TIGR00426:cztS_silS_copS:AcCoA-C-Actrans:transamin_PhnW:Intracellular trafficking, secretion, and vesicular transport:Defense mechanisms:Information storage and processing:DNA transformation:Cellular processes:Other:Fatty acid and phospholipid metabolism:Phosphorus compounds:Central intermediary metabolism:Cellular processes and signaling:Metabolism:Poorly characterized:Metabolism:Metabolism:Global:Signal Transduction:Environmental Information Processing:Translation:Genetic Information Processing:Xenobiotics Biodegradation and Metabolism:Metabolism of Terpenoids and Polyketides:Metabolism of Cofactors and Vitamins:Metabolism of Other Amino Acids:Amino Acid Metabolism:Lipid Metabolism" 402 "Parvulin-like peptidyl-prolyl isomerase:Type II secretory pathway, component PulD:Type II secretory pathway, component PulF:Multidrug resistance efflux pump:Type II secretory pathway, pseudopilin PulG:DNA-binding HTH domain-containing proteins:Type II secretory pathway, ATPase PulE/Tfp pilus assembly pathway, ATPase PilB:RTX toxins and related Ca2+-binding proteins:Type II secretory pathway, component PulM:Type II secretory pathway, component PulK:Type II secretory pathway, component PulL:ABC-type protease/lipase transport system, ATPase and permease components:Type II secretory pathway, component PulJ:Transcription:Cell motility:Posttranslational modification, protein turnover, chaperones:ABC transporters:Two-component system:Bacterial secretion system:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:gspI:typeII_sec_gspH:typeII_sec_gspL:typeII_sec_gspG:gspJ:type_I_sec_PrtD:type_I_hlyD:GspF:type_II_gspD:type_II_gspE:Intracellular trafficking, secretion, and vesicular transport:Defense mechanisms:Protein and peptide secretion and trafficking:Protein fate:Environmental Information Processing:Signal Transduction:Membrane Transport:Poorly characterized:Metabolism:Cellular processes and signaling:Information storage and processing:Pathogenesis:Cellular processes" 403 "Energy production and conversion:Prephenate dehydratase:Peroxiredoxin:FKBP-type peptidyl-prolyl cis-trans isomerases 2:Cytochrome c biogenesis factor:Na+-transporting NADH:ubiquinone oxidoreductase, subunit NqrD:Membrane-associated lipoprotein involved in thiamine biosynthesis:Phosphoserine aminotransferase:Na+-transporting NADH:ubiquinone oxidoreductase, subunit NqrE:Cytochrome c-type biogenesis protein CcmE:Na+-transporting NADH:ubiquinone oxidoreductase, subunit NqrC:3-deoxy-D-manno-octulosonic acid (KDO) 8-phosphate synthase:Amino acid transport and metabolism:Coenzyme transport and metabolism:Cell wall/membrane/envelope biogenesis:Posttranslational modification, protein turnover, chaperones:Glycine serine and threonine metabolism:Phenylalanine tyrosine and tryptophan biosynthesis:Lipopolysaccharide biosynthesis:Methane metabolism:Vitamin B6 metabolism:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:nrfE:dsbE:KDO8P_synth:serC_1:CM_P2:nqrC:nqrD:nqrE:Cell envelope:Energy Metabolism:Amino Acid Metabolism:Glycan Biosynthesis and Metabolism:Metabolism of Cofactors and Vitamins:Global:Metabolism:Energy metabolism:Electron transport:Protein fate:Protein folding and stabilization:Transport and binding proteins:Cations and iron carrying compounds:Amino acid biosynthesis:Aromatic amino acid family:Serine family:Metabolism:Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides:Cellular processes and signaling:Metabolism" 404 "Triosephosphate isomerase:Thiamine biosynthesis ATP pyrophosphatase:DNA primase (bacterial type):Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family:Superfamily II DNA and RNA helicases:Metal-dependent proteases with possible chaperone activity:Pseudouridylate synthases, 23S RNA-specific:S-adenosylmethionine:tRNA-ribosyltransferase-isomerase (queuine synthetase):Predicted sulfurtransferase:16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases:Acyl-CoA hydrolase:Uncharacterized conserved protein:Carbohydrate transport and metabolism:Coenzyme transport and metabolism:Lipid transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:Replication, recombination and repair:Posttranslational modification, protein turnover, chaperones:Glycolysis / Gluconeogenesis:Fructose and mannose metabolism:Streptomycin biosynthesis:Inositol phosphate metabolism:Thiamine metabolism:Aminoacyl-tRNA biosynthesis:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:RNA degradation:DNA replication:Sulfur relay system:General function prediction only:Function unknown:rluA_subfam:TIGR00093:queA:gcp_kae1:TIGR00342:tim:dnaG:Cellular processes and signaling:Carbohydrate Metabolism:Metabolism of Cofactors and Vitamins:Biosynthesis of Other Secondary Metabolites:Genetic Information Processing:Translation:Folding Sorting and Degradation:Replication and Repair:Global:Metabolism:Energy metabolism:Glycolysis/gluconeogenesis:DNA metabolism:DNA replication, recombination, and repair:Protein synthesis:tRNA and rRNA base modification:Protein fate:Degradation of proteins, peptides, and glycopeptides:Information storage and processing:Metabolism:Metabolism:Poorly characterized" 405 "Energy production and conversion:Acetyltransferases:Universal stress protein UspA and related nucleotide-binding proteins:NADPH:quinone reductase and related Zn-dependent oxidoreductases:Predicted Zn-dependent peptidases:Putative intracellular protease/amidase:NADH dehydrogenase, FAD-containing subunit:Amidases related to nicotinamidase:Cyclopropane fatty acid synthase and related methyltransferases:Uncharacterized protein conserved in bacteria:Uncharacterized protein conserved in bacteria:Uncharacterized conserved protein:Uncharacterized conserved protein:Predicted membrane protein:Uncharacterized conserved protein:Predicted proteasome-type protease:Cell wall/membrane/envelope biogenesis:Posttranslational modification, protein turnover, chaperones:Oxidative phosphorylation:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:Function unknown:Signal transduction mechanisms:DNA:oxido_YhdH:quinone_pig3:poly_P_AMP_trns:Metabolism:Poorly characterized:Metabolism:Cellular processes and signaling:Enzymes of unknown specificity:Unknown function:Conserved:Hypothetical proteins:Phosphorus compounds:Central intermediary metabolism:Energy Metabolism" 406 "Sulfite reductase, beta subunit (hemoprotein):3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase and related enzymes:Predicted flavoprotein:Peroxiredoxin:ABC-type sulfate transport system, permease component:Transcriptional regulator:Predicted permeases:ABC-type amino acid transport system, permease component:ABC-type amino acid transport/signal transduction systems, periplasmic component/domain:Cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes:ABC-type sulfate/molybdate transport systems, ATPase component:Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain:ABC-type metal ion transport system, periplasmic component/surface antigen:ABC-type sulfate transport system, periplasmic component:Probable taurine catabolism dioxygenase:GTPases - Sulfate adenylate transferase subunit 1:Predicted esterase of the alpha/beta hydrolase fold:Uncharacterized protein conserved in bacteria:ABC-type sulfate transport system, permease component:Phenylpropionate dioxygenase and related ring-hydroxylating dioxygenases, large terminal subunit:Uncharacterized small protein:Amino acid transport and metabolism:Coenzyme transport and metabolism:Transcription:Posttranslational modification, protein turnover, chaperones:Inorganic ion transport and metabolism:Purine metabolism:Taurine and hypotaurine metabolism:Selenocompound metabolism:Thiamine metabolism:Porphyrin and chlorophyll metabolism:Sulfur metabolism:Metabolic pathways:Microbial metabolism in diverse environments:ABC transporters:Sulfur relay system:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:Function unknown:Signal transduction mechanisms:small_GTP:cysH:3a0106s01:3a0106s02:3a0106s03:HEQRo_perm_3TM:CysD:FMN_reduc_SsuE:Metabolism:Cellular processes and signaling:Information storage and processing:General:Unknown function:Anions:Amino acids, peptides and amines:Transport and binding proteins:Sulfur metabolism:Central intermediary metabolism:Metabolism:Metabolism:Global:Membrane Transport:Environmental Information Processing:Folding Sorting and Degradation:Genetic Information Processing:Metabolism of Cofactors and Vitamins:Metabolism of Other Amino Acids:Nucleotide Metabolism:Poorly characterized:Energy Metabolism" 407 "Adenylosuccinate lyase:Cation transport ATPase:Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain:Cation/multidrug efflux pump:Membrane-fusion protein:Outer membrane protein:Alkyl sulfatase and related hydrolases:Putative multicopper oxidases:Cation transport ATPase:Methylase involved in ubiquinone/menaquinone biosynthesis:Uncharacterized protein involved in copper resistance:Uncharacterized protein conserved in bacteria:Predicted membrane protein:Predicted membrane protein:Uncharacterized copper-binding protein:Nucleotide transport and metabolism:Coenzyme transport and metabolism:Transcription:Cell wall/membrane/envelope biogenesis:Inorganic ion transport and metabolism:Purine metabolism:Alanine aspartate and glutamate metabolism:Metabolic pathways:Biosynthesis of secondary metabolites:Two-component system:Secondary metabolites biosynthesis, transport and catabolism:Function unknown:Signal transduction mechanisms:TIGR00003:2A0602:purB:cztR_silR_copR:TAT_signal_seq:ATPase_P-type:RND_mfp:outer_NodT:Intracellular trafficking, secretion, and vesicular transport:Defense mechanisms:Transport and binding proteins:Protein and peptide secretion and trafficking:Protein fate:Purine ribonucleotide biosynthesis:Purines, pyrimidines, nucleosides, and nucleotides:Metabolism:Metabolism:Global:Signal Transduction:Environmental Information Processing:Amino Acid Metabolism:Poorly characterized:Nucleotide Metabolism:Metabolism:Cellular processes and signaling:Information storage and processing:Porins:Cations and iron carrying compounds:Unknown substrate" 408 "Dihydrodipicolinate synthase/N-acetylneuraminate lyase:ABC-type Fe3+-siderophore transport system, permease component:ABC-type amino acid transport system, permease component:ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components:Acyl carrier protein phosphodiesterase:Metal-dependent amidase/aminoacylase/carboxypeptidase:Outer membrane receptor proteins, mostly Fe transport:Uncharacterized conserved protein:Transcriptional regulators:Acyl-CoA dehydrogenases:AraC-type DNA-binding domain-containing proteins:Sugar phosphate permease:Arabinose efflux permease:Sterol desaturase:Uncharacterized protein conserved in bacteria:ABC-type uncharacterized transport system, duplicated ATPase component:Ketosteroid isomerase homolog:Amino acid transport and metabolism:Carbohydrate transport and metabolism:Coenzyme transport and metabolism:Lipid transport and metabolism:Transcription:Cell wall/membrane/envelope biogenesis:Inorganic ion transport and metabolism:Lysine biosynthesis:Phenylalanine metabolism:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:ABC transporters:General function prediction only:Function unknown:HEQRo_perm_3TM:TonB-siderophor:amidohydrolases:Information storage and processing:Porins:Amino acids, peptides and amines:Transport and binding proteins:Degradation of proteins, peptides, and glycopeptides:Protein fate:Metabolism:Global:Membrane Transport:Environmental Information Processing:Metabolism:Amino Acid Metabolism:Poorly characterized:Metabolism:Cellular processes and signaling" 409 "Energy production and conversion:Adenylosuccinate synthase:Uncharacterized conserved protein:Membrane protease subunits, stomatin/prohibitin homologs:Molecular chaperone:Ferredoxin:UDP-3-O-acyl-N-acetylglucosamine deacetylase:NifU homolog involved in Fe-S cluster formation:Serine acetyltransferase:DnaJ-domain-containing proteins 1:Cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes:Predicted transcriptional regulator:GTPases:Uncharacterized protein conserved in bacteria:Amino acid transport and metabolism:Nucleotide transport and metabolism:Transcription:Cell wall/membrane/envelope biogenesis:Posttranslational modification, protein turnover, chaperones:Purine metabolism:Alanine aspartate and glutamate metabolism:Cysteine and methionine metabolism:Lipopolysaccharide biosynthesis:Thiamine metabolism:Sulfur metabolism:Metabolic pathways:Microbial metabolism in diverse environments:Sulfur relay system:General function prediction only:Function unknown:TIGR00049:purA:lpxC:hscB:rrf2_super:cysE:hflK:HscA:iscU:IscS:fdx_isc:GTP_HflX:YhgI_GntY:iscX_yfhJ:Metabolism:Poorly characterized:Metabolism:Metabolism:Global:Folding Sorting and Degradation:Genetic Information Processing:Metabolism of Cofactors and Vitamins:Glycan Biosynthesis and Metabolism:Amino Acid Metabolism:Nucleotide Metabolism:Energy Metabolism:Purines, pyrimidines, nucleosides, and nucleotides:Purine ribonucleotide biosynthesis:Protein synthesis:tRNA and rRNA base modification:Protein fate:Protein folding and stabilization:Unknown function:General:Amino acid biosynthesis:Serine family:Biosynthesis of cofactors, prosthetic groups, and carriers:Other:Cell envelope:Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides:Information storage and processing:Cellular processes and signaling" 410 "ATPases with chaperone activity, ATP-binding subunit:Serine/threonine protein phosphatase:Hemolysin-coregulated protein (uncharacterized):Uncharacterized protein conserved in bacteria:Uncharacterized conserved protein, contains FHA domain:Uncharacterized protein conserved in bacteria:Uncharacterized protein conserved in bacteria:Uncharacterized protein conserved in bacteria:Uncharacterized protein conserved in bacteria:Uncharacterized protein conserved in bacteria:Uncharacterized protein conserved in bacteria:Uncharacterized protein conserved in bacteria:Uncharacterized protein conserved in bacteria:Uncharacterized protein conserved in bacteria:Uncharacterized protein conserved in bacteria:Transcriptional regulator containing GAF, AAA-type ATPase, and DNA binding domains:Uncharacterized conserved protein:Transcription:Posttranslational modification, protein turnover, chaperones:Aminoacyl-tRNA biosynthesis:Bacterial secretion system:Function unknown:Signal transduction mechanisms:vgr_GE:VI_effect_Hcp1:VI_ClpV1:VI_chp_1:VI_IcmF:IV_VI_DotU:VI_chp_3:VI_chp_4:VI_FHA:VI_chp_2:VI_zyme:VI_chp_5:VI_chp_6:VI_chp_7:Translation:Cellular processes and signaling:Information storage and processing:Pathogenesis:Cellular processes:Genetic Information Processing:Membrane Transport:Environmental Information Processing:Poorly characterized" 411 "Energy production and conversion:Isopropylmalate/homocitrate/citramalate synthases:Fe-S oxidoreductase:FAD/FMN-containing dehydrogenases:Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II:Asparagine synthase (glutamine-hydrolyzing):Transcriptional regulators:Sterol desaturase:Uncharacterized protein, possibly involved in utilization of glycolate and propanediol:Amino acid transport and metabolism:Lipid transport and metabolism:Transcription:Valine leucine and isoleucine biosynthesis:Pyruvate metabolism:Glyoxylate and dicarboxylate metabolism:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:glcD:Metabolism:Carbohydrate Metabolism:Amino Acid Metabolism:Global:Metabolism:Energy metabolism:Other:Information storage and processing:Metabolism:Poorly characterized" 412 "Methionine aminopeptidase:Nucleotidyltransferase/DNA polymerase involved in DNA repair:Superfamily II DNA and RNA helicases:Transcriptional regulator:Protein chain release factor B:Co/Zn/Cd efflux system component:Uncharacterized membrane protein:Arsenate reductase and related proteins, glutaredoxin family:Uncharacterized conserved protein:Uncharacterized protein conserved in bacteria:Uncharacterized bacitracin resistance protein:Membrane transporters of cations and cationic drugs:Mg/Co/Ni transporter MgtE (contains CBS domain):Plasmid stabilization system protein:Predicted transcriptional regulator:Translation, ribosomal structure and biogenesis:Transcription:Replication, recombination and repair:Inorganic ion transport and metabolism:Peptidoglycan biosynthesis:RNA degradation:General function prediction only:Function unknown:mgtE:met_pdase_I:undec_PP_bacA:CDF:arsC_related:release_prfH:release_rtcB:Defense mechanisms:Metabolism:Cellular processes and signaling:Information storage and processing:Biosynthesis and degradation of murein sacculus and peptidoglycan:Cell envelope:Cations and iron carrying compounds:Transport and binding proteins:Protein modification and repair:Protein fate:Translation factors:Other:Protein synthesis:DNA interactions:Regulatory functions:Metabolism:Folding Sorting and Degradation:Genetic Information Processing:Poorly characterized:Glycan Biosynthesis and Metabolism" 413 "Energy production and conversion:ATPases with chaperone activity, ATP-binding subunit:DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32):NAD-dependent aldehyde dehydrogenases:Enoyl-CoA hydratase/carnithine racemase:Acyl-CoA dehydrogenases:Uncharacterized conserved protein:Uncharacterized conserved protein:Putative Ser protein kinase:Lipid transport and metabolism:Transcription:Posttranslational modification, protein turnover, chaperones:Fatty acid metabolism:Valine leucine and isoleucine degradation:Geraniol degradation:Lysine degradation:Benzoate degradation:Tryptophan metabolism:beta-Alanine metabolism:Inositol phosphate metabolism:Naphthalene degradation:Aminobenzoate degradation:Propanoate metabolism:Butanoate metabolism:Limonene and pinene degradation:Caprolactam degradation:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:RNA polymerase:Function unknown:Signal transduction mechanisms:MMSDH:rpoS_proteo:Metabolism:Metabolism of Other Amino Acids:Amino Acid Metabolism:Lipid Metabolism:Carbohydrate Metabolism:Genetic Information Processing:Transcription:Global:Metabolism:Energy metabolism:Amino acids and amines:Transcription:Transcription factors:Information storage and processing:Cellular processes and signaling:Metabolism:Poorly characterized:Xenobiotics Biodegradation and Metabolism:Metabolism of Terpenoids and Polyketides" 414 "ABC-type antimicrobial peptide transport system, permease component:Cytosine/adenosine deaminases:ABC-type metal ion transport system, periplasmic component/surface adhesin:Periplasmic protein TonB, links inner and outer membranes:ABC-type Mn2+/Zn2+ transport systems, permease components:ABC-type Mn/Zn transport systems, ATPase component:Outer membrane protein:ABC-type Fe3+ transport system, periplasmic component:Putative multicopper oxidases:Protein related to penicillin acylase:Enterochelin esterase and related enzymes:Uncharacterized iron-regulated membrane protein:Predicted thioesterase involved in non-ribosomal peptide biosynthesis:Outer membrane receptor for ferric coprogen and ferric-rhodotorulic acid:Nucleotide transport and metabolism:Translation, ribosomal structure and biogenesis:Cell wall/membrane/envelope biogenesis:Inorganic ion transport and metabolism:ABC transporters:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:Function unknown:tonB_Cterm:TonB-siderophor:outer_NodT:Intracellular trafficking, secretion, and vesicular transport:Defense mechanisms:Membrane Transport:Poorly characterized:Metabolism:Cellular processes and signaling:Information storage and processing:Porins:Cations and iron carrying compounds:Transport and binding proteins:Environmental Information Processing" 415 "Energy production and conversion:Anaerobic dehydrogenases, typically selenocysteine-containing:Chemotaxis protein histidine kinase and related kinases:Chemotaxis signal transduction protein:Methyl-accepting chemotaxis protein:Methylase of chemotaxis methyl-accepting proteins:Chemotaxis protein; stimulates methylation of MCP proteins:Chemotaxis response regulator containing a CheY-like receiver domain and a methylesterase domain:Nitrate/TMAO reductases, membrane-bound tetraheme cytochrome c subunit:Nitrate reductase cytochrome c-type subunit:Uncharacterized protein involved in formation of periplasmic nitrate reductase:Cell motility:Inorganic ion transport and metabolism:Nitrogen metabolism:Microbial metabolism in diverse environments:Two-component system:Bacterial chemotaxis:Signal transduction mechanisms:napF:NAPA:napC_nirT:Energy metabolism:Energy Metabolism:Environmental Information Processing:Signal Transduction:Cellular Processes:Cell Motility:Global:Metabolism:Central intermediary metabolism:Nitrogen metabolism:Metabolism:Electron transport:Cellular processes and signaling:Metabolism" 416 "Energy production and conversion:Acetate kinase:Universal stress protein UspA and related nucleotide-binding proteins:Predicted exonuclease of the beta-lactamase fold involved in RNA processing:Phosphate transport regulator (distant homolog of PhoU):DnaK suppressor protein:Predicted phosphatase homologous to the C-terminal domain of histone macroH2A1:Uncharacterized protein conserved in bacteria:Phosphoketolase:Carbohydrate transport and metabolism:Translation, ribosomal structure and biogenesis:Inorganic ion transport and metabolism:Taurine and hypotaurine metabolism:Pyruvate metabolism:Propanoate metabolism:Methane metabolism:Carbon fixation pathways in prokaryotes:Metabolic pathways:Microbial metabolism in diverse environments:General function prediction only:Function unknown:Signal transduction mechanisms:ackA:TIGR00153:Information storage and processing:Carbohydrate Metabolism:Energy Metabolism:Metabolism of Other Amino Acids:Global:Metabolism:Energy metabolism:Fermentation:Hypothetical proteins:Conserved:Metabolism:Cellular processes and signaling:Metabolism:Poorly characterized" 417 "Ribosomal protein L4:Ribosomal protein L23:Ribosomal protein S8:Ribosomal protein L6P/L9E:Ribosomal protein S5:Ribosomal protein S13:Ribosomal protein S19:Ribosomal protein L15:Preprotein translocase subunit SecY:Ribosomal protein L18:Ribosomal protein L36:Ribosomal protein L30/L7E:Translation, ribosomal structure and biogenesis:Ribosome:Protein export:Bacterial secretion system:L18_bact:3a0501s007:rpsE_bact:rpmJ_bact:rpsS_bact:rplO_bact:rpmD_bact:bact_S13:L6_bact:rplD_bact:Intracellular trafficking, secretion, and vesicular transport:Ribosomal proteins: synthesis and modification:Translation:Folding Sorting and Degradation:Environmental Information Processing:Membrane Transport:Protein synthesis:Genetic Information Processing:Protein fate:Protein and peptide secretion and trafficking:Information storage and processing:Cellular processes and signaling" 418 "Energy production and conversion:Thiol-disulfide isomerase and thioredoxins:Signal transduction histidine kinase:Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain:Cation/multidrug efflux pump:Membrane-fusion protein:Outer membrane protein:Protein-disulfide isomerase:Arabinose efflux permease:Thiol:disulfide interchange protein:Carbohydrate transport and metabolism:Transcription:Cell wall/membrane/envelope biogenesis:Posttranslational modification, protein turnover, chaperones:Two-component system:Signal transduction mechanisms:cztS_silS_copS:cztR_silR_copR:RND_mfp:Intracellular trafficking, secretion, and vesicular transport:Defense mechanisms:Signal Transduction:Environmental Information Processing:Metabolism:Cellular processes and signaling:Information storage and processing:Unknown substrate:Transport and binding proteins" 419 "Ribosomal protein S2:Ribosomal protein S15P/S13E:Transcription elongation factor:Ribosomal protein L7/L12:Ribosomal protein S16:Ribosomal protein L10:Ribosomal protein L21:Translation elongation factor Ts:tRNA-(guanine-N1)-methyltransferase:RimM protein, required for 16S rRNA processing:Predicted metal-binding, possibly nucleic acid-binding protein:Translation, ribosomal structure and biogenesis:Transcription:Ribosome:General function prediction only:S16:L21:trmD:tsf:L12:S15_bact:rpsB_bact:NusA:16S_RimM:tRNA and rRNA base modification:Translation:Transcription:Transcription factors:RNA processing:Protein synthesis:Ribosomal proteins: synthesis and modification:Genetic Information Processing:Translation factors:Information storage and processing:Poorly characterized" 420 "Dihydroxyacid dehydratase/phosphogluconate dehydratase:Indole-3-glycerol phosphate synthase:Protoheme ferro-lyase (ferrochelatase):Molybdopterin biosynthesis enzyme:Guanosine polyphosphate pyrophosphohydrolases/synthetases:Aspartate/tyrosine/aromatic aminotransferase:ATPases involved in chromosome partitioning:Glycine cleavage system H protein (lipoate-binding):Monoamine oxidase:D-Tyr-tRNAtyr deacylase:Beta-lactamase class C and other penicillin binding proteins:Threonine aldolase:Membrane-bound lytic murein transglycosylase B:Uncharacterized protein involved in outer membrane biogenesis:Paraquat-inducible protein B:D-serine dehydratase:Uncharacterized protein conserved in bacteria:ABC-type phosphate/phosphonate transport system, periplasmic component:Hydroxypyruvate isomerase:ABC-type phosphate/phosphonate transport system, ATPase component:Short-chain alcohol dehydrogenase of unknown specificity:Cell cycle control, cell division, chromosome partitioning:Amino acid transport and metabolism:Carbohydrate transport and metabolism:Coenzyme transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:Cell wall/membrane/envelope biogenesis:Inorganic ion transport and metabolism:Purine metabolism:Glycine serine and threonine metabolism:Valine leucine and isoleucine biosynthesis:Arginine and proline metabolism:Histidine metabolism:Tyrosine metabolism:Phenylalanine metabolism:Tryptophan metabolism:Phenylalanine tyrosine and tryptophan biosynthesis:Glyoxylate and dicarboxylate metabolism:Pantothenate and CoA biosynthesis:Porphyrin and chlorophyll metabolism:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:ABC transporters:General function prediction only:Function unknown:Signal transduction mechanisms:hemH:ilvD:molyb_syn:TIGR00256:gcvH:spoT_relA:3A0109s03R:D_Ser_am_lyase:MltB_2:Defense mechanisms:Metabolism:Cellular processes and signaling:Information storage and processing:Biosynthesis and degradation of murein sacculus and peptidoglycan:Cell envelope:Heme, porphyrin, and cobalamin:Biosynthesis of cofactors, prosthetic groups, and carriers:Pyruvate family:Amino acid biosynthesis:Adaptations to atypical conditions:Cellular processes:Anions:Transport and binding proteins:tRNA aminoacylation:Protein synthesis:Amino acids and amines:Energy metabolism:Metabolism:Metabolism:Global:Membrane Transport:Environmental Information Processing:Metabolism of Cofactors and Vitamins:Amino Acid Metabolism:Nucleotide Metabolism:Carbohydrate Metabolism:Poorly characterized" 421 "Energy production and conversion:Predicted EndoIII-related endonuclease:Aspartate/tyrosine/aromatic aminotransferase:Glycosyltransferase:Peroxiredoxin:Topoisomerase IA:ADP-heptose:LPS heptosyltransferase:Cytochrome c biogenesis factor:Cytochrome c-type biogenesis protein CcmE:UTP:GlnB (protein PII) uridylyltransferase:Heme exporter protein D:Cytochrome c biogenesis factor:Predicted NADH:ubiquinone oxidoreductase, subunit RnfC:Predicted NADH:ubiquinone oxidoreductase, subunit RnfG:Predicted NADH:ubiquinone oxidoreductase, subunit RnfE:Amino acid transport and metabolism:Replication, recombination and repair:Cell wall/membrane/envelope biogenesis:Posttranslational modification, protein turnover, chaperones:Lysine biosynthesis:Lipopolysaccharide biosynthesis:Metabolic pathways:Microbial metabolism in diverse environments:ABC transporters:Two-component system:Base excision repair:nrfE:dsbE:topA_bact:nth:UTase_glnD:rnfC:rnfG:rnfE:heptsyl_trn_I:cytochro_ccmD:cytochro_ccmI:DapC_gpp:Intracellular trafficking, secretion, and vesicular transport:Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides:Amino Acid Metabolism:Glycan Biosynthesis and Metabolism:Genetic Information Processing:Replication and Repair:Environmental Information Processing:Membrane Transport:Signal Transduction:Global:Metabolism:Energy metabolism:Electron transport:Regulatory functions:Protein interactions:DNA metabolism:DNA replication, recombination, and repair:Protein fate:Protein folding and stabilization:Cell envelope:Metabolism:Information storage and processing:Cellular processes and signaling:Metabolism" 422 "Energy production and conversion:Dihydroorotate dehydrogenase:Orotidine-5'-phosphate decarboxylase:Uncharacterized conserved protein:Uroporphyrinogen-III decarboxylase:Fe-S oxidoreductase:Disulfide bond chaperones of the HSP33 family:Putative effector of murein hydrolase:Predicted transcriptional regulators:3-deoxy-D-manno-octulosonic-acid transferase:Arabinose efflux permease:Uncharacterized protein conserved in bacteria:Nicotinamide mononucleotide transporter:Predicted proline hydroxylase:Kef-type K+ transport system, predicted NAD-binding component:Nucleotide transport and metabolism:Carbohydrate transport and metabolism:Coenzyme transport and metabolism:Transcription:Cell wall/membrane/envelope biogenesis:Posttranslational modification, protein turnover, chaperones:Inorganic ion transport and metabolism:Pyrimidine metabolism:Lipopolysaccharide biosynthesis:Porphyrin and chlorophyll metabolism:Metabolic pathways:Biosynthesis of secondary metabolites:Function unknown:YbgI_SA1388:pyrD_sub2:hemE:NMN_trans_PnuC:pyrF:Information storage and processing:Pyridine nucleotides:Heme, porphyrin, and cobalamin:Biosynthesis of cofactors, prosthetic groups, and carriers:General:Unknown function:Pyrimidine ribonucleotide biosynthesis:Purines, pyrimidines, nucleosides, and nucleotides:Metabolism:Metabolism:Global:Metabolism of Cofactors and Vitamins:Glycan Biosynthesis and Metabolism:Poorly characterized:Nucleotide Metabolism:Metabolism:Cellular processes and signaling" 423 "Flagellar biosynthesis/type III secretory pathway protein:Type II secretory pathway, component PulD:AraC-type DNA-binding domain-containing proteins:Type III secretory pathway, lipoprotein EscJ:NAD+--asparagine ADP-ribosyltransferase:Transcription:Cell motility:Bacterial secretion system:Signal transduction mechanisms:III_needle:yscI_hrpB_dom:HrpE_YscL_not:type_III_yscD:type_III_yscE:type_III_yscG:type_III_yopR:type_III_yscB:type_III_yscC:III_secr_YscJ:Intracellular trafficking, secretion, and vesicular transport:Cellular processes:Membrane Transport:Environmental Information Processing:Pathogenesis:Information storage and processing:Cellular processes and signaling" 424 "Energy production and conversion:tRNA-dihydrouridine synthase:Uncharacterized conserved protein:Predicted GTPase:Signal recognition particle GTPase:Pseudouridylate synthases, 23S RNA-specific:rRNA methylase:Uncharacterized protein conserved in bacteria:Ferredoxin:Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain:Uncharacterized protein conserved in bacteria:Cytochrome c5:Predicted transcriptional regulator, BolA superfamily:Translation, ribosomal structure and biogenesis:Transcription:Aminoacyl-tRNA biosynthesis:Protein export:Bacterial secretion system:General function prediction only:Function unknown:Signal transduction mechanisms:rluA_subfam:rRNA_methyl_1:ftsY:TIGR00149_YbjQ:nifR3_yhdG:Obg_CgtA:Intracellular trafficking, secretion, and vesicular transport:Information storage and processing:Translation:Folding Sorting and Degradation:Environmental Information Processing:Membrane Transport:Protein synthesis:Other:tRNA and rRNA base modification:Protein fate:Protein and peptide secretion and trafficking:Unknown function:Enzymes of unknown specificity:General:Genetic Information Processing:Cellular processes and signaling:Metabolism:Poorly characterized" 425 "Chromatin structure and dynamics:Energy production and conversion:Serine-pyruvate aminotransferase/archaeal aspartate aminotransferase:Deacetylases, including yeast histone deacetylase and acetoin utilization protein:Adenosylmethionine-8-amino-7-oxononanoate aminotransferase:Acetyl-CoA acetyltransferase:Anaerobic dehydrogenases, typically selenocysteine-containing:Phosphoserine phosphatase:Signal transduction histidine kinase:Glycine/D-amino acid oxidases (deaminating):NAD-dependent aldehyde dehydrogenases:Gamma-aminobutyrate permease and related permeases:Ferredoxin:Purine-cytosine permease and related proteins:2'-5' RNA ligase:Uncharacterized protein required for formate dehydrogenase activity:Probable taurine catabolism dioxygenase:Nitrate/nitrite transporter:Predicted membrane protein:Uncharacterized protein, possibly involved in utilization of glycolate and propanediol:Predicted protein-disulfide isomerase:Glyoxylate carboligase:Amino acid transport and metabolism:Nucleotide transport and metabolism:Coenzyme transport and metabolism:Lipid transport and metabolism:Translation, ribosomal structure and biogenesis:Posttranslational modification, protein turnover, chaperones:Inorganic ion transport and metabolism:Fatty acid metabolism:Valine leucine and isoleucine degradation:Geraniol degradation:Arginine and proline metabolism:Benzoate degradation:Taurine and hypotaurine metabolism:Phosphonate and phosphinate metabolism:alpha-Linolenic acid metabolism:Glyoxylate and dicarboxylate metabolism:Methane metabolism:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:Function unknown:Signal transduction mechanisms:fdhD_narQ:sensory_box:HAD-SF-IB:glyox_carbo_lig:Fdhalpha-like:AcCoA-C-Actrans:2_5_ligase:transamin_PhnW:Phosphorus compounds:Central intermediary metabolism:Metabolism:Metabolism:Global:Xenobiotics Biodegradation and Metabolism:Metabolism of Terpenoids and Polyketides:Metabolism of Other Amino Acids:Amino Acid Metabolism:Lipid Metabolism:Energy Metabolism:RNA processing:Carbohydrate Metabolism:Unknown function:Enzymes of unknown specificity:Information storage and processing:Cellular processes and signaling:Metabolism:Poorly characterized:Transcription:Small molecule interactions:Regulatory functions:Other:Fatty acid and phospholipid metabolism:Electron transport:Energy metabolism" 426 "Glutamyl- and glutaminyl-tRNA synthetases:Cysteinyl-tRNA synthetase:Protein chain release factor A:Predicted metal-dependent hydrolase:Glycosyltransferase:Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2:Signal peptidase I:Preprotein translocase subunit YidC:Glutamate racemase:Uncharacterized protein conserved in bacteria:Methylase of polypeptide chain release factors:Outer membrane lipoprotein involved in outer membrane biogenesis:Coenzyme transport and metabolism:Translation, ribosomal structure and biogenesis:Cell wall/membrane/envelope biogenesis:D-Glutamine and D-glutamate metabolism:Lipopolysaccharide biosynthesis:Aminoacyl-tRNA biosynthesis:Metabolic pathways:Protein export:Bacterial secretion system:Sulfur relay system:General function prediction only:Function unknown:prfA:TIGR00043:glut_race:cysS:glnS:hemK_fam:lolB:sigpep_I_bact:yidC_oxa1_cterm:Intracellular trafficking, secretion, and vesicular transport:Information storage and processing:Metabolism of Other Amino Acids:Glycan Biosynthesis and Metabolism:Genetic Information Processing:Translation:Folding Sorting and Degradation:Environmental Information Processing:Membrane Transport:Global:Metabolism:Protein synthesis:Other:tRNA aminoacylation:Translation factors:Protein fate:Protein and peptide secretion and trafficking:Protein modification and repair:Cell envelope:Biosynthesis and degradation of murein sacculus and peptidoglycan:Metabolism:Cellular processes and signaling:Metabolism:Poorly characterized" 427 "Energy production and conversion:5-enolpyruvylshikimate-3-phosphate synthase:Phosphoribosylamine-glycine ligase:Excinuclease ATPase subunit:F0F1-type ATP synthase, epsilon subunit (mitochondrial delta subunit):Glutathione S-transferase:Transglutaminase-like enzymes, putative cysteine proteases:Na+-transporting NADH:ubiquinone oxidoreductase, subunit NqrD:Membrane-associated lipoprotein involved in thiamine biosynthesis:Na+-transporting NADH:ubiquinone oxidoreductase, subunit NqrE:Na+-transporting NADH:ubiquinone oxidoreductase, subunit NqrC:Na+-transporting NADH:ubiquinone oxidoreductase, subunit NqrF:3-deoxy-D-manno-octulosonic acid (KDO) 8-phosphate synthase:Amino acid transport and metabolism:Nucleotide transport and metabolism:Coenzyme transport and metabolism:Replication, recombination and repair:Cell wall/membrane/envelope biogenesis:Posttranslational modification, protein turnover, chaperones:Oxidative phosphorylation:Purine metabolism:Lipopolysaccharide biosynthesis:Metabolic pathways:Biosynthesis of secondary metabolites:Nucleotide excision repair:uvra:purD:ATP_synt_epsi:aroA:KDO8P_synth:nqrC:nqrD:nqrE:nqrF:Information storage and processing:Energy Metabolism:Nucleotide Metabolism:Glycan Biosynthesis and Metabolism:Genetic Information Processing:Replication and Repair:Global:Metabolism:Energy metabolism:ATP-proton motive force interconversion:Purines, pyrimidines, nucleosides, and nucleotides:Purine ribonucleotide biosynthesis:DNA metabolism:DNA replication, recombination, and repair:Transport and binding proteins:Cations and iron carrying compounds:Amino acid biosynthesis:Aromatic amino acid family:Cell envelope:Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides:Metabolism:Cellular processes and signaling:Metabolism" 428 "Energy production and conversion:Arginase/agmatinase/formimionoglutamate hydrolase, arginase family:Lactoylglutathione lyase and related lyases:Amino acid transporters:Spermidine/putrescine-binding periplasmic protein:TRAP-type C4-dicarboxylate transport system, periplasmic component:Predicted acyl-CoA transferases/carnitine dehydratase:Acyl-CoA dehydrogenases:Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain:Citrate lyase beta subunit:TRAP-type C4-dicarboxylate transport system, small permease component:Protein involved in meta-pathway of phenol degradation:Uncharacterized copper-binding protein:L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily:Amino acid transport and metabolism:Carbohydrate transport and metabolism:Lipid transport and metabolism:Transcription:Cell wall/membrane/envelope biogenesis:Inorganic ion transport and metabolism:Citrate cycle (TCA cycle):Fatty acid metabolism:Valine leucine and isoleucine degradation:Arginine and proline metabolism:beta-Alanine metabolism:Propanoate metabolism:Metabolic pathways:Biosynthesis of secondary metabolites:Two-component system:General function prediction only:Signal transduction mechanisms:dctP:agmatinase:Metabolism:Cellular processes and signaling:Information storage and processing:Carbohydrates, organic alcohols, and acids:Transport and binding proteins:Metabolism:Metabolism:Global:Signal Transduction:Environmental Information Processing:Metabolism of Other Amino Acids:Amino Acid Metabolism:Lipid Metabolism:Poorly characterized:Carbohydrate Metabolism" 429 "Energy production and conversion:Uncharacterized flavoproteins:Nucleoside-diphosphate-sugar epimerases:Universal stress protein UspA and related nucleotide-binding proteins:Coproporphyrinogen III oxidase and related Fe-S oxidoreductases:Zn-dependent alcohol dehydrogenases:Cytochrome c peroxidase:Uncharacterized conserved protein:Hemerythrin:Uncharacterized conserved protein:Carbohydrate transport and metabolism:Coenzyme transport and metabolism:Cell wall/membrane/envelope biogenesis:Inorganic ion transport and metabolism:Glycolysis / Gluconeogenesis:Fatty acid metabolism:Tyrosine metabolism:Lipopolysaccharide biosynthesis:Chloroalkane and chloroalkene degradation:Naphthalene degradation:Porphyrin and chlorophyll metabolism:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:General function prediction only:Function unknown:Signal transduction mechanisms:hemN:heptose_epim:hemeryth_dom:PPK2_P_aer:Poorly characterized:Cell envelope:Heme, porphyrin, and cobalamin:Biosynthesis of cofactors, prosthetic groups, and carriers:Phosphorus compounds:Metabolism:Global:Central intermediary metabolism:Metabolism:Xenobiotics Biodegradation and Metabolism:Metabolism of Cofactors and Vitamins:Glycan Biosynthesis and Metabolism:Amino Acid Metabolism:Lipid Metabolism:Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides:Carbohydrate Metabolism:Cellular processes and signaling:Metabolism" 430 "Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family:Periplasmic protease:Aspartate/tyrosine/aromatic aminotransferase:Predicted P-loop-containing kinase:Phosphotransferase system mannitol/fructose-specific IIA domain (Ntr-type):Pterin-4a-carbinolamine dehydratase:Chemotaxis response regulator containing a CheY-like receiver domain and a methylesterase domain:NAD-specific glutamate dehydrogenase:Succinylglutamate desuccinylase:Phenylalanine-4-hydroxylase:Amino acid transport and metabolism:Carbohydrate transport and metabolism:Coenzyme transport and metabolism:Cell wall/membrane/envelope biogenesis:Cell motility:Posttranslational modification, protein turnover, chaperones:Alanine aspartate and glutamate metabolism:Cysteine and methionine metabolism:Arginine and proline metabolism:Tyrosine metabolism:Phenylalanine metabolism:Phenylalanine tyrosine and tryptophan biosynthesis:Novobiocin biosynthesis:Nitrogen metabolism:Metabolic pathways:Biosynthesis of secondary metabolites:Two-component system:Bacterial chemotaxis:Phosphotransferase system (PTS):General function prediction only:Signal transduction mechanisms:prc:Phe4hydrox_mono:nitro_reg_IIA:arg_catab_astE:PTS:Energy Metabolism:Amino Acid Metabolism:Biosynthesis of Other Secondary Metabolites:Environmental Information Processing:Membrane Transport:Signal Transduction:Cellular Processes:Cell Motility:Global:Metabolism:Energy metabolism:Amino acids and amines:Protein fate:Protein modification and repair:Signal transduction:Metabolism:Cellular processes and signaling:Metabolism:Poorly characterized" 431 "3-oxoacyl-(acyl-carrier-protein) synthase:Predicted membrane protein:Hemolysin-coregulated protein (uncharacterized):Uncharacterized protein conserved in bacteria:Uncharacterized conserved protein, contains FHA domain:Uncharacterized protein conserved in bacteria:Uncharacterized protein conserved in bacteria:Uncharacterized protein conserved in bacteria:Uncharacterized protein conserved in bacteria:Uncharacterized protein conserved in bacteria:Uncharacterized protein conserved in bacteria:Uncharacterized conserved protein:Uncharacterized protein conserved in bacteria:Uncharacterized conserved protein:Lipid transport and metabolism:Fatty acid biosynthesis:Metabolic pathways:Bacterial secretion system:Secondary metabolites biosynthesis, transport and catabolism:Function unknown:Signal transduction mechanisms:vgr_GE:VI_effect_Hcp1:IV_VI_DotU:VI_chp_3:VI_chp_4:VI_FHA:VI_chp_2:VI_chp_5:VI_chp_8:Global:Membrane Transport:Environmental Information Processing:Poorly characterized:Lipid Metabolism:Metabolism:Cellular processes and signaling:Pathogenesis:Cellular processes:Metabolism:Metabolism" 432 "Putative translation initiation inhibitor, yjgF family:Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily):FOG: Ankyrin repeat:Membrane proteins related to metalloendopeptidases:ABC-type amino acid transport/signal transduction systems, periplasmic component/domain:Transcriptional regulator:Phosphatidylserine/phosphatidylglycerophosphate/cardiolipin synthases and related enzymes:Cytochrome c peroxidase:Predicted flavoprotein involved in K+ transport:Probable taurine catabolism dioxygenase:AraC-type DNA-binding domain-containing proteins:Putative NADPH-quinone reductase (modulator of drug activity B):DNA-binding HTH domain-containing proteins:Arabinose efflux permease:Putative NADH-flavin reductase:Uncharacterized protein conserved in bacteria:Predicted periplasmic protein:Uncharacterized protein conserved in bacteria:Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain:Uncharacterized secreted protein:Amino acid transport and metabolism:Carbohydrate transport and metabolism:Lipid transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:Cell wall/membrane/envelope biogenesis:Inorganic ion transport and metabolism:Glycerophospholipid metabolism:Metabolic pathways:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:Function unknown:Signal transduction mechanisms:GGDEF:2A0106:reg_near_HchA:Global:Lipid Metabolism:Metabolism:Poorly characterized:Metabolism:Cellular processes and signaling:Information storage and processing:Other:Signal transduction:Unknown substrate:Transport and binding proteins:Metabolism" 433 "Energy production and conversion:Glutamyl- and glutaminyl-tRNA synthetases:Transketolase:Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase:Phosphoglycerate dehydrogenase and related dehydrogenases:Glycine/serine hydroxymethyltransferase:Adenosylmethionine-8-amino-7-oxononanoate aminotransferase:Ketopantoate hydroxymethyltransferase:Panthothenate synthetase:Prolyl-tRNA synthetase:CTP synthase (UTP-ammonia lyase):DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32):Phosphatidylserine decarboxylase:Tartrate dehydratase alpha subunit/Fumarate hydratase class I, N-terminal domain:Methylase involved in ubiquinone/menaquinone biosynthesis:Rhodanese-related sulfurtransferase:Uncharacterized protein conserved in bacteria:Amino acid transport and metabolism:Nucleotide transport and metabolism:Carbohydrate transport and metabolism:Coenzyme transport and metabolism:Lipid transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:Inorganic ion transport and metabolism:Glycolysis / Gluconeogenesis:Citrate cycle (TCA cycle):Pentose phosphate pathway:Ubiquinone and other terpenoid-quinone biosynthesis:Pyrimidine metabolism:Glycine serine and threonine metabolism:Cysteine and methionine metabolism:beta-Alanine metabolism:Cyanoamino acid metabolism:Glycerophospholipid metabolism:One carbon pool by folate:Methane metabolism:Carbon fixation pathways in prokaryotes:Pantothenate and CoA biosynthesis:Biotin metabolism:Aminoacyl-tRNA biosynthesis:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:RNA polymerase:Sulfur relay system:Function unknown:panC:PS_decarb:panB:tktlase_bact:PyrG:proS_fam_II:glnS:bioA:ttdA_fumA_fumB:GAPDH-I:MenG_MenH_UbiE:RpoD_Cterm:Lipid Metabolism:Energy Metabolism:Global:Carbohydrate Metabolism:Metabolism:Energy metabolism:Glycolysis/gluconeogenesis:Pentose phosphate pathway:Fatty acid and phospholipid metabolism:Biosynthesis:Purines, pyrimidines, nucleosides, and nucleotides:Pyrimidine ribonucleotide biosynthesis:Transcription:Transcription factors:Protein synthesis:tRNA aminoacylation:Biosynthesis of cofactors, prosthetic groups, and carriers:Biotin:Menaquinone and ubiquinone:Pantothenate and coenzyme A:Information storage and processing:Metabolism:Poorly characterized:Folding Sorting and Degradation:Translation:Transcription:Genetic Information Processing:Metabolism of Cofactors and Vitamins:Metabolism of Other Amino Acids:Amino Acid Metabolism:Metabolism:Nucleotide Metabolism" 434 "Energy production and conversion:Lactoylglutathione lyase and related lyases:Glycosyltransferase:NADPH:quinone reductase and related Zn-dependent oxidoreductases:Signal transduction histidine kinase:Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain:Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs:Uncharacterized low-complexity proteins:Multidrug resistance efflux pump:Beta-lactamase class C and other penicillin binding proteins:Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain:Xanthine/uracil permeases:Arabinose efflux permease:Uncharacterized conserved protein:Fe2+-dicitrate sensor, membrane component:Glucose dehydrogenase:Amino acid transport and metabolism:Nucleotide transport and metabolism:Carbohydrate transport and metabolism:Transcription:Cell wall/membrane/envelope biogenesis:Inorganic ion transport and metabolism:Glycolysis / Gluconeogenesis:Pyruvate metabolism:Chloroalkane and chloroalkene degradation:Propanoate metabolism:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:Two-component system:General function prediction only:Function unknown:Signal transduction mechanisms:glyox_I:efflux_EmrB:ncs2:cztS_silS_copS:cztR_silR_copR:PQQ_enz_alc_DH:Defense mechanisms:Metabolism:Carbohydrate Metabolism:Xenobiotics Biodegradation and Metabolism:Environmental Information Processing:Signal Transduction:Global:Metabolism:Energy metabolism:Other:Transport and binding proteins:Nucleosides, purines and pyrimidines:Other:Information storage and processing:Cellular processes and signaling:Metabolism:Poorly characterized" 435 "Energy production and conversion:Phosphoribosylaminoimidazolesuccinocarboxamide (SAICAR) synthase:Thioredoxin reductase:Phosphoenolpyruvate synthase/pyruvate phosphate dikinase:Membrane proteins related to metalloendopeptidases:Peroxiredoxin:Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes:Outer membrane protein:Preprotein translocase subunit SecB:Uncharacterized protein conserved in bacteria:Glycine cleavage system regulatory protein:Predicted periplasmic or secreted lipoprotein:Fe-S cluster protector protein:Uncharacterized protein involved in outer membrane biogenesis:Uncharacterized lipoprotein:Uncharacterized protein conserved in bacteria:Amino acid transport and metabolism:Nucleotide transport and metabolism:Carbohydrate transport and metabolism:Cell wall/membrane/envelope biogenesis:Posttranslational modification, protein turnover, chaperones:Purine metabolism:Pyrimidine metabolism:Pyruvate metabolism:Methane metabolism:Carbon fixation pathways in prokaryotes:Nicotinate and nicotinamide metabolism:Aminoacyl-tRNA biosynthesis:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:Protein export:Bacterial secretion system:General function prediction only:Function unknown:purC:secB:TRX_reduct:PEP_synth:type_I_sec_TolC:Intracellular trafficking, secretion, and vesicular transport:Poorly characterized:Carbohydrate Metabolism:Energy Metabolism:Nucleotide Metabolism:Metabolism of Cofactors and Vitamins:Genetic Information Processing:Translation:Folding Sorting and Degradation:Environmental Information Processing:Membrane Transport:Global:Metabolism:Energy metabolism:Electron transport:Glycolysis/gluconeogenesis:Purines, pyrimidines, nucleosides, and nucleotides:Purine ribonucleotide biosynthesis:Protein fate:Protein and peptide secretion and trafficking:Transport and binding proteins:Porins:Cellular processes and signaling:Metabolism:Metabolism" 436 "Energy production and conversion:Transketolase:S-adenosylmethionine synthetase:Peroxiredoxin:Isocitrate dehydrogenases:Phosphoenolpyruvate synthase/pyruvate phosphate dikinase:Superoxide dismutase:Putative intracellular protease/amidase:MoxR-like ATPases:Transcription elongation factor:ABC-type amino acid transport/signal transduction systems, periplasmic component/domain:Acyl-CoA hydrolase:Acyl dehydratase:Methylase involved in ubiquinone/menaquinone biosynthesis:Uncharacterized conserved protein:Outer membrane protein W:Putative sterol carrier protein:Predicted oxidoreductase related to nitroreductase:Amino acid transport and metabolism:Carbohydrate transport and metabolism:Coenzyme transport and metabolism:Lipid transport and metabolism:Transcription:Cell wall/membrane/envelope biogenesis:Posttranslational modification, protein turnover, chaperones:Inorganic ion transport and metabolism:Citrate cycle (TCA cycle):Pentose phosphate pathway:Cysteine and methionine metabolism:Selenocompound metabolism:Glutathione metabolism:Pyruvate metabolism:Methane metabolism:Carbon fixation pathways in prokaryotes:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:ABC transporters:General function prediction only:Function unknown:Signal transduction mechanisms:prok_nadp_idh:tktlase_bact:metK:3A0103s03R:PfpI:PEP_synth:greA:AhpC:Glycolysis/gluconeogenesis:Energy metabolism:Other:Central intermediary metabolism:Metabolism:Metabolism:Global:Membrane Transport:Environmental Information Processing:Metabolism of Other Amino Acids:Amino Acid Metabolism:Energy Metabolism:Transcription:Carbohydrate Metabolism:Transcription factors:Protein fate:Degradation of proteins, peptides, and glycopeptides:Transport and binding proteins:Amino acids, peptides and amines:Cellular processes:Adaptations to atypical conditions:Information storage and processing:Cellular processes and signaling:Metabolism:Poorly characterized:TCA cycle:Pentose phosphate pathway" 437 "Chemotaxis signal transduction protein:Methyl-accepting chemotaxis protein:Flagellar basal body P-ring biosynthesis protein:Methylase of chemotaxis methyl-accepting proteins:Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains:Negative regulator of flagellin synthesis (anti-sigma28 factor):Outer membrane protein and related peptidoglycan-associated (lipo)proteins:Tfp pilus assembly protein FimV:Flagellar biosynthesis/type III secretory pathway chaperone:Response regulator containing a CheY-like receiver domain and a GGDEF domain:Predicted glycosyltransferase:Transcription:Cell wall/membrane/envelope biogenesis:Cell motility:Posttranslational modification, protein turnover, chaperones:Two-component system:Bacterial chemotaxis:Flagellar assembly:Signal transduction mechanisms:GGDEF:flgA_cterm:FimV_Cterm:FlgM_jcvi:Intracellular trafficking, secretion, and vesicular transport:Signal Transduction:Signal transduction:Other:Information storage and processing:Cellular processes and signaling:Environmental Information Processing:Cellular processes:Cell Motility:Cellular Processes:Chemotaxis and motility" 438 "tRNA-dihydrouridine synthase:3-oxoacyl-(acyl-carrier-protein) synthase:ATPase components of ABC transporters with duplicated ATPase domains:Transcriptional regulator:Sulfate permease and related transporters (MFS superfamily):Predicted ATP-dependent serine protease:Transcriptional regulator:Amidases related to nicotinamidase:Predicted transcriptional regulators:3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases:Cytochrome P450:Transcriptional regulators:AraC-type DNA-binding domain-containing proteins:Uncharacterized small membrane protein:Cyanate permease:Arabinose efflux permease:Predicted membrane protein:Predicted alpha/beta hydrolase:Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain:Carbohydrate transport and metabolism:Lipid transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:Posttranslational modification, protein turnover, chaperones:Inorganic ion transport and metabolism:Fatty acid biosynthesis:Valine leucine and isoleucine degradation:Peptidoglycan biosynthesis:Metabolic pathways:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:Function unknown:Signal transduction mechanisms:sensory_box:sms:CynX:mono_pep_trsgly:fabF:phn_lysR:Poorly characterized:Lipid Metabolism:Amino Acid Metabolism:Glycan Biosynthesis and Metabolism:Global:Metabolism:Fatty acid and phospholipid metabolism:Biosynthesis:Regulatory functions:Small molecule interactions:DNA metabolism:DNA replication, recombination, and repair:Transport and binding proteins:Other:Cell envelope:Biosynthesis and degradation of murein sacculus and peptidoglycan:Information storage and processing:Cellular processes and signaling:Metabolism:Metabolism" 439 "Chromatin structure and dynamics:Energy production and conversion:Deacetylases, including yeast histone deacetylase and acetoin utilization protein:Zn-dependent hydrolases, including glyoxylases:Glycine/D-amino acid oxidases (deaminating):Amino acid permeases:NAD-dependent aldehyde dehydrogenases:NADH:flavin oxidoreductases, Old Yellow Enzyme family:Acyl-CoA dehydrogenases:P pilus assembly protein, chaperone PapD:P pilus assembly protein, porin PapC:Predicted enzyme of the cupin superfamily:Uncharacterized protein conserved in bacteria:Phosphate-selective porin:Uncharacterized protein conserved in bacteria:Amino acid transport and metabolism:Lipid transport and metabolism:Cell motility:Inorganic ion transport and metabolism:Fatty acid metabolism:Valine leucine and isoleucine degradation:beta-Alanine metabolism:Propanoate metabolism:Caprolactam degradation:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:Function unknown:vgr_GE:Intracellular trafficking, secretion, and vesicular transport:Carbohydrate Metabolism:Poorly characterized:Cellular processes and signaling:Information storage and processing:Metabolism:Metabolism:Global:Xenobiotics Biodegradation and Metabolism:Metabolism of Other Amino Acids:Amino Acid Metabolism:Lipid Metabolism:Metabolism" 440 "Gamma-glutamyl phosphate reductase:Nucleoside diphosphate kinase:Ribose 5-phosphate isomerase:Sulfite reductase, beta subunit (hemoprotein):FAD synthase:Formyltetrahydrofolate hydrolase:Uncharacterized homolog of plant Iojap protein:Nicotinic acid mononucleotide adenylyltransferase:Putative threonine efflux protein:Uncharacterized stress-induced protein:Uncharacterized conserved protein:Uncharacterized protein conserved in bacteria:Amino acid transport and metabolism:Nucleotide transport and metabolism:Carbohydrate transport and metabolism:Coenzyme transport and metabolism:Inorganic ion transport and metabolism:Pentose phosphate pathway:Purine metabolism:Pyrimidine metabolism:Arginine and proline metabolism:Glyoxylate and dicarboxylate metabolism:One carbon pool by folate:Riboflavin metabolism:Nicotinate and nicotinamide metabolism:Porphyrin and chlorophyll metabolism:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:Function unknown:rpiA:ribF:iojap_ybeB:cyt_tran_rel:tRNA_RlmH_YbeA:TIGR00255:proA:PurU:CobG:Amino acid biosynthesis:Carbohydrate Metabolism:Nucleotide Metabolism:Amino Acid Metabolism:Metabolism of Cofactors and Vitamins:Global:Metabolism:Energy metabolism:Pentose phosphate pathway:Purines, pyrimidines, nucleosides, and nucleotides:Purine ribonucleotide biosynthesis:Protein synthesis:tRNA and rRNA base modification:Hypothetical proteins:Conserved:Unknown function:General:Metabolism:Glutamate family:Biosynthesis of cofactors, prosthetic groups, and carriers:Heme, porphyrin, and cobalamin:Riboflavin, FMN, and FAD:Metabolism:Poorly characterized" 441 "Energy production and conversion:Glutathione synthase/Ribosomal protein S6 modification enzyme (glutaminyl transferase):Predicted amidohydrolase:Uncharacterized homolog of Blt101:NAD-dependent aldehyde dehydrogenases:Ribonucleases G and E:Transcriptional regulators:Transcriptional regulators:Choline dehydrogenase and related flavoproteins:Phosphoenolpyruvate carboxylase:Uncharacterized protein conserved in bacteria:Uncharacterized protein conserved in bacteria:Amino acid transport and metabolism:Coenzyme transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:Pyruvate metabolism:Methane metabolism:Carbon fixation pathways in prokaryotes:Metabolic pathways:Microbial metabolism in diverse environments:General function prediction only:Function unknown:RNaseEG:gcw_chp:Carbohydrate Metabolism:Poorly characterized:Metabolism:Information storage and processing:Degradation of RNA:Transcription:Metabolism:Global:Energy Metabolism:Metabolism" 442 "Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), B subunit:Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), A subunit:Replicative DNA helicase:Nucleoside-diphosphate-sugar epimerases:Glycine/D-amino acid oxidases (deaminating):Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases):Recombinational DNA repair ATPase (RecF pathway):Rad3-related DNA helicases:Metal-dependent hydrolases of the beta-lactamase superfamily I:Aspartyl aminopeptidase:HrpA-like helicases:Cobalamin biosynthesis protein CbiD:Precorrin-6B methylase 1:3-methyladenine DNA glycosylase:DNA recombination-dependent growth factor C:Predicted esterase:Predicted aspartyl protease:ABC-type transport system, involved in lipoprotein release, permease component:Amino acid transport and metabolism:Carbohydrate transport and metabolism:Coenzyme transport and metabolism:Lipid transport and metabolism:Transcription:Replication, recombination and repair:Cell wall/membrane/envelope biogenesis:Galactose metabolism:Amino sugar and nucleotide sugar metabolism:Porphyrin and chlorophyll metabolism:Metabolic pathways:ABC transporters:DNA replication:Homologous recombination:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:cbiD:recf:DnaB:parE_Gneg:parC_Gneg:DEAH_box_HrpA:lolCE:clan_AA_DTGA:rimK_rel_E_lig:CbiE:MnmC_Cterm:Protein fate:tRNA and rRNA base modification:Protein synthesis:DNA replication, recombination, and repair:DNA metabolism:Metabolism:Metabolism:Global:Membrane Transport:Environmental Information Processing:Replication and Repair:Genetic Information Processing:Metabolism of Cofactors and Vitamins:Enzymes of unknown specificity:Carbohydrate Metabolism:Biosynthesis of cofactors, prosthetic groups, and carriers:Heme, porphyrin, and cobalamin:Information storage and processing:Cellular processes and signaling:Metabolism:Poorly characterized:Unknown function:Degradation of proteins, peptides, and glycopeptides:Protein and peptide secretion and trafficking" 443 "Energy production and conversion:Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases:Cytosine deaminase and related metal-dependent hydrolases:ATPases of the AAA+ class:Selenocysteine lyase:Transcriptional regulator:Enoyl-CoA hydratase/carnithine racemase:Hydrolases of the alpha/beta superfamily:D-alanine-D-alanine ligase and related ATP-grasp enzymes:Chromosome segregation ATPases:Acetyltransferases, including N-acetylases of ribosomal proteins:Ketopantoate reductase:Acyl-CoA dehydrogenases:FOG: GGDEF domain:Arabinose efflux permease:Na+-transporting NADH:ubiquinone oxidoreductase, subunit NqrF:Adenylate cyclase:Predicted double-glycine peptidase:Transcriptional activator of acetoin/glycerol metabolism:Predicted enzyme of the cupin superfamily:Nucleoside 2-deoxyribosyltransferase:Uncharacterized conserved protein:Uncharacterized protein related to arylsulfate sulfotransferase involved in siderophore biosynthesis:Cell cycle control, cell division, chromosome partitioning:Amino acid transport and metabolism:Nucleotide transport and metabolism:Carbohydrate transport and metabolism:Coenzyme transport and metabolism:Lipid transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:Cell wall/membrane/envelope biogenesis:Posttranslational modification, protein turnover, chaperones:Fatty acid metabolism:Purine metabolism:Valine leucine and isoleucine degradation:Geraniol degradation:Lysine degradation:Arginine and proline metabolism:Phenylalanine metabolism:Benzoate degradation:Tryptophan metabolism:beta-Alanine metabolism:Cyanoamino acid metabolism:D-Alanine metabolism:Peptidoglycan biosynthesis:Aminobenzoate degradation:Propanoate metabolism:Styrene degradation:Butanoate metabolism:Pantothenate and CoA biosynthesis:Limonene and pinene degradation:Caprolactam degradation:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:Function unknown:Signal transduction mechanisms:GGDEF:efflux_EmrB:apbA_panE:D_ala_D_alaTIGR:guan_deamin:Biosynthesis of cofactors, prosthetic groups, and carriers:Other:Transport and binding proteins:Other:Purines, pyrimidines, nucleosides, and nucleotides:Metabolism:Metabolism:Global:Xenobiotics Biodegradation and Metabolism:Metabolism of Terpenoids and Polyketides:Metabolism of Cofactors and Vitamins:Glycan Biosynthesis and Metabolism:Metabolism of Other Amino Acids:Amino Acid Metabolism:Nucleotide Metabolism:Lipid Metabolism:Poorly characterized:Carbohydrate Metabolism:Metabolism:Cellular processes and signaling:Information storage and processing:Biosynthesis and degradation of murein sacculus and peptidoglycan:Cell envelope:Other:Signal transduction:Pantothenate and coenzyme A" 444 "ABC-type Fe3+-siderophore transport system, permease component:Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain:DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog:Outer membrane receptor proteins, mostly Fe transport:Ferredoxin subunits of nitrite reductase and ring-hydroxylating dioxygenases:Uncharacterized iron-regulated protein:Fe2+-dicitrate sensor, membrane component:Putative heme degradation protein:ABC-type hemin transport system, periplasmic component:ABC-type hemin transport system, ATPase component:Outer membrane receptor for ferrienterochelin and colicins:Outer membrane receptor for ferric coprogen and ferric-rhodotorulic acid:Transcription:Inorganic ion transport and metabolism:ABC transporters:RNA polymerase:General function prediction only:Function unknown:Signal transduction mechanisms:TonB-siderophor:TonB-hemin:sigma70-ECF:Cellular processes and signaling:Information storage and processing:Porins:Transport and binding proteins:Membrane Transport:Environmental Information Processing:Genetic Information Processing:Transcription:Poorly characterized:Metabolism" 445 "Predicted amidohydrolase:Glycine/D-amino acid oxidases (deaminating):Choline-glycine betaine transporter:Adenosine deaminase:Protein tyrosine/serine phosphatase:DNA-binding HTH domain-containing proteins:Transposase and inactivated derivatives:Amino acid transport and metabolism:Nucleotide transport and metabolism:Transcription:Replication, recombination and repair:Cell wall/membrane/envelope biogenesis:Aminoacyl-tRNA biosynthesis:General function prediction only:Signal transduction mechanisms:bcct:Poorly characterized:Metabolism:Cellular processes and signaling:Information storage and processing:Other:Transport and binding proteins:Genetic Information Processing:Translation" 446 "Energy production and conversion:Membrane protease subunits, stomatin/prohibitin homologs:Predicted flavoprotein:Methyl-accepting chemotaxis protein:Membrane-fusion protein:Threonine dehydrogenase and related Zn-dependent dehydrogenases:ABC-type metal ion transport system, ATPase component:Outer membrane protein:Acyl-CoA dehydrogenases:ABC-type metal ion transport system, permease component:AraC-type DNA-binding domain-containing proteins:Sugar phosphate permease:Cytochrome c553:Putative silver efflux pump:Signal transduction histidine kinase:Amino acid transport and metabolism:Carbohydrate transport and metabolism:Lipid transport and metabolism:Transcription:Cell wall/membrane/envelope biogenesis:Cell motility:Posttranslational modification, protein turnover, chaperones:Inorganic ion transport and metabolism:Porphyrin and chlorophyll metabolism:ABC transporters:Two-component system:General function prediction only:Signal transduction mechanisms:sensory_box:2A0601:RND_mfp:FMN_reduc_MsuE:sulfur_SfnB:Intracellular trafficking, secretion, and vesicular transport:Cations and iron carrying compounds:Unknown substrate:Transport and binding proteins:Small molecule interactions:Regulatory functions:Sulfur metabolism:Central intermediary metabolism:Signal Transduction:Membrane Transport:Environmental Information Processing:Metabolism of Cofactors and Vitamins:Metabolism:Poorly characterized:Metabolism:Cellular processes and signaling:Information storage and processing" 447 "Energy production and conversion:Short-chain dehydrogenases of various substrate specificities:3-oxoacyl-[acyl-carrier-protein] synthase III:2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases:Non-ribosomal peptide synthetase modules and related proteins:Cytochrome P450:Arabinose efflux permease:Ketosteroid isomerase-related protein:Carbohydrate transport and metabolism:Coenzyme transport and metabolism:Lipid transport and metabolism:Fatty acid biosynthesis:Bisphenol degradation:Polycyclic aromatic hydrocarbon degradation:Aminobenzoate degradation:Limonene and pinene degradation:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:fabH:AA-adenyl-dom:Fatty acid and phospholipid metabolism:Lipid Metabolism:Metabolism of Terpenoids and Polyketides:Xenobiotics Biodegradation and Metabolism:Global:Metabolism:Metabolism:Biosynthesis:Metabolism:Poorly characterized" 448 "Energy production and conversion:Uncharacterized flavoproteins:Coproporphyrinogen III oxidase and related Fe-S oxidoreductases:Cytochrome c peroxidase:Cytochrome c, mono- and diheme variants:Uncharacterized conserved protein:Hemerythrin:Cbb3-type cytochrome oxidase, cytochrome c subunit:Outer membrane protein W:Cbb3-type cytochrome oxidase, subunit 1:Uncharacterized conserved protein:Coenzyme transport and metabolism:Cell wall/membrane/envelope biogenesis:Posttranslational modification, protein turnover, chaperones:Inorganic ion transport and metabolism:Oxidative phosphorylation:Porphyrin and chlorophyll metabolism:Metabolic pathways:Biosynthesis of secondary metabolites:Function unknown:hemN:ccoN:ccoO:ccoP:hemeryth_dom:PPK2_P_aer:Heme, porphyrin, and cobalamin:Energy Metabolism:Metabolism of Cofactors and Vitamins:Global:Metabolism:Central intermediary metabolism:Phosphorus compounds:Energy metabolism:Electron transport:Biosynthesis of cofactors, prosthetic groups, and carriers:Metabolism:Cellular processes and signaling:Metabolism:Poorly characterized" 449 "Flagellar biosynthesis/type III secretory pathway ATPase:Flagellar motor switch/type III secretory pathway protein:Type III secretory pathway, component EscV:Type III secretory pathway, component EscS:Uncharacterized conserved protein:Cell motility:Bacterial secretion system:Function unknown:fliI_yscN:hrcV:fliQ_rel_III:type_III_YscX:type_III_SycN:type_III_tyeA:SpaO_YscQ:LcrH_SycD:LcrE:LcrG_PcrG:Intracellular trafficking, secretion, and vesicular transport:Energy metabolism:Membrane Transport:Environmental Information Processing:ATP-proton motive force interconversion:Cellular processes:Pathogenesis:Cellular processes and signaling:Poorly characterized" 450 "Predicted permease:ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components:Predicted transcriptional regulators:Predicted amidophosphoribosyltransferases:ADP-ribose pyrophosphatase:ABC-type spermidine/putrescine transport system, permease component II:Transcriptional regulator:Probable taurine catabolism dioxygenase:Transcriptional regulators:Transposase and inactivated derivatives:Uncharacterized protein conserved in bacteria:Uncharacterized conserved protein:Predicted methylated DNA-protein cysteine methyltransferase:Predicted membrane protein:ABC-type uncharacterized transport system, permease component:Uncharacterized protein conserved in bacteria:Amino acid transport and metabolism:Nucleotide transport and metabolism:Transcription:Replication, recombination and repair:Inorganic ion transport and metabolism:ABC transporters:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:Function unknown:fkbM_fam:SsuA_fam:UHCUDC:Information storage and processing:Other:Transport and binding proteins:Membrane Transport:Environmental Information Processing:Poorly characterized:Metabolism" 451 "Energy production and conversion:Glutamyl- and glutaminyl-tRNA synthetases:Glutamate synthase domain 2:FAD/FMN-containing dehydrogenases:Predicted phosphatases:Predicted SAM-dependent methyltransferases:ABC-type multidrug transport system, ATPase and permease components:Deoxyxylulose-5-phosphate synthase:16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases:Uncharacterized protein, possibly involved in aromatic compounds catabolism:SAM-dependent methyltransferases related to tRNA (uracil-5-)-methyltransferase:Uncharacterized conserved protein:Amino acid transport and metabolism:Coenzyme transport and metabolism:Lipid transport and metabolism:Translation, ribosomal structure and biogenesis:Alanine aspartate and glutamate metabolism:Glyoxylate and dicarboxylate metabolism:Porphyrin and chlorophyll metabolism:Terpenoid backbone biosynthesis:Nitrogen metabolism:Aminoacyl-tRNA biosynthesis:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:ABC transporters:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:Function unknown:TIGR00093:dxs:unchar_dom_1:gltX_bact:rumA:PGP_bact:MsbA_lipidA:Defense mechanisms:Information storage and processing:Carbohydrate Metabolism:Energy Metabolism:Amino Acid Metabolism:Metabolism of Cofactors and Vitamins:Metabolism of Terpenoids and Polyketides:Genetic Information Processing:Translation:Environmental Information Processing:Membrane Transport:Global:Metabolism:Energy metabolism:Sugars:Protein synthesis:tRNA aminoacylation:tRNA and rRNA base modification:Transport and binding proteins:Other:Biosynthesis of cofactors, prosthetic groups, and carriers:Thiamine:Metabolism:Cellular processes and signaling:Metabolism:Poorly characterized" 452 "Energy production and conversion:Arginyl-tRNA synthetase:Short-chain dehydrogenases of various substrate specificities:Phosphate/sulphate permeases:Glycerophosphoryl diester phosphodiesterase:DnaJ-domain-containing proteins 1:Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis/translation initiation factor 2B, gamma/epsilon subunits (eIF-2Bgamma/eIF-2Bepsilon):Transcriptional regulator:Phosphate transport regulator (distant homolog of PhoU):Uncharacterized conserved protein:Putative homoserine kinase type II (protein kinase fold):Type II secretory pathway, ATPase PulE/Tfp pilus assembly pathway, ATPase PilB:Ubiquinone biosynthesis protein COQ7:Uncharacterized conserved protein:Predicted phosphotransferase related to Ser/Thr protein kinases:Coenzyme transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:Cell wall/membrane/envelope biogenesis:Cell motility:Posttranslational modification, protein turnover, chaperones:Inorganic ion transport and metabolism:Ubiquinone and other terpenoid-quinone biosynthesis:Glycine serine and threonine metabolism:Glycerophospholipid metabolism:Aminoacyl-tRNA biosynthesis:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:Bacterial secretion system:General function prediction only:Function unknown:TIGR00153:argS:thrB_alt:Intracellular trafficking, secretion, and vesicular transport:Cellular processes and signaling:Lipid Metabolism:Amino Acid Metabolism:Metabolism of Cofactors and Vitamins:Genetic Information Processing:Translation:Environmental Information Processing:Membrane Transport:Global:Metabolism:Protein synthesis:tRNA aminoacylation:Hypothetical proteins:Conserved:Amino acid biosynthesis:Aspartate family:Information storage and processing:Metabolism:Metabolism:Poorly characterized" 453 "Energy production and conversion:Phenylalanyl-tRNA synthetase alpha subunit:Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases:Ribosome recycling factor:Malic enzyme:Preprotein translocase subunit SecD:Carbamoylphosphate synthase large subunit (split gene in MJ):Carbamoylphosphate synthase small subunit:Aspartokinases:Uridylate kinase:Preprotein translocase subunit YidC:Glycyl-tRNA synthetase, beta subunit:Glycyl-tRNA synthetase, alpha subunit:Lysyl-tRNA synthetase (class II):Putative threonine efflux protein:Amino acid transport and metabolism:Nucleotide transport and metabolism:Translation, ribosomal structure and biogenesis:Pyrimidine metabolism:Alanine aspartate and glutamate metabolism:Glycine serine and threonine metabolism:Cysteine and methionine metabolism:Lysine biosynthesis:Pyruvate metabolism:Aminoacyl-tRNA biosynthesis:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:Protein export:Bacterial secretion system:gatA:glyS:glyQ:pheS:frr:lysS_bact:asp_kin_monofn:2A0604s01:2A76:CPSaseIIsmall:CPSaseII_lrg:pyrH_bact:yidC_oxa1_cterm:Intracellular trafficking, secretion, and vesicular transport:Transport and binding proteins:Amino acids, peptides and amines:Amino acid biosynthesis:Aspartate family:Information storage and processing:Cellular processes and signaling:Metabolism:Protein fate:Translation factors:tRNA aminoacylation:Protein synthesis:Pyrimidine ribonucleotide biosynthesis:Nucleotide and nucleoside interconversions:Purines, pyrimidines, nucleosides, and nucleotides:Metabolism:Metabolism:Global:Membrane Transport:Environmental Information Processing:Folding Sorting and Degradation:Translation:Genetic Information Processing:Amino Acid Metabolism:Nucleotide Metabolism:Protein and peptide secretion and trafficking:Carbohydrate Metabolism" 454 "Ribosomal protein L13:Ribosomal protein S9:Ribosomal protein L28:Transcription antiterminator:Ribosomal protein L31:Ribosomal protein L33:Ribosomal protein S20:Translation initiation factor 1 (IF-1):Preprotein translocase subunit SecE:Preprotein translocase subunit SecG:Translation, ribosomal structure and biogenesis:Transcription:Aminoacyl-tRNA biosynthesis:Ribosome:Protein export:Bacterial secretion system:infA:L28:S20:S21p:L31:secG:nusG:secE_bact:rpmG_bact:rplM_bact:Intracellular trafficking, secretion, and vesicular transport:Cellular processes and signaling:Protein and peptide secretion and trafficking:Protein fate:Translation factors:Ribosomal proteins: synthesis and modification:Protein synthesis:Transcription factors:Transcription:Genetic Information Processing:Membrane Transport:Environmental Information Processing:Folding Sorting and Degradation:Information storage and processing:Translation" 455 "DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32):Glutaredoxin and related proteins:Fe2+/Zn2+ uptake regulation proteins:Bacterial nucleoid DNA-binding protein:ATPases involved in chromosome partitioning:Cold shock proteins:Uncharacterized protein (competence- and mitomycin-induced):Acetyltransferases, including N-acetylases of ribosomal proteins:Predicted acetyltransferase:Cell cycle control, cell division, chromosome partitioning:Translation, ribosomal structure and biogenesis:Transcription:Replication, recombination and repair:Posttranslational modification, protein turnover, chaperones:Inorganic ion transport and metabolism:RNA polymerase:General function prediction only:cinA_cterm:hip:rpoH_proteo:DNA metabolism:Metabolism:Transcription:Poorly characterized:Cellular processes and signaling:Genetic Information Processing:Information storage and processing:Transcription factors:Transcription:DNA replication, recombination, and repair" 456 "Energy production and conversion:Uroporphyrinogen-III methylase:Predicted Fe-S oxidoreductases:Transcriptional regulators:Cytochrome c, mono- and diheme variants:Cytochrome c551/c552:Coenzyme transport and metabolism:Transcription:Porphyrin and chlorophyll metabolism:Nitrogen metabolism:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:General function prediction only:cobA_cysG_Cterm:rSAM_NirJ:Heme, porphyrin, and cobalamin:Energy Metabolism:Metabolism of Cofactors and Vitamins:Global:Metabolism:Biosynthesis of cofactors, prosthetic groups, and carriers:Metabolism:Information storage and processing:Metabolism:Poorly characterized" 457 "Energy production and conversion:NADPH:quinone reductase and related Zn-dependent oxidoreductases:Predicted transcriptional regulators:ABC-type amino acid transport/signal transduction systems, periplasmic component/domain:Predicted hydrolase (HAD superfamily):Uncharacterized conserved protein:Predicted transcriptional regulators:Transcriptional regulators:Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain:Uncharacterized protein conserved in bacteria:Uncharacterized enzyme of heme biosynthesis:Uncharacterized protein conserved in bacteria:Uncharacterized protein conserved in bacteria:Predicted hydrolase of the alpha/beta-hydrolase fold:Amino acid transport and metabolism:Coenzyme transport and metabolism:Transcription:Chlorocyclohexane and chlorobenzene degradation:Chloroalkane and chloroalkene degradation:Porphyrin and chlorophyll metabolism:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:General function prediction only:Function unknown:Signal transduction mechanisms:HAD_type_II:CadR-PbrR:quinone_pig3:Metabolism of Cofactors and Vitamins:Metabolism:Poorly characterized:Metabolism:Information storage and processing:Enzymes of unknown specificity:Unknown function:Metabolism:Global:Xenobiotics Biodegradation and Metabolism:Cellular processes and signaling" 458 "Energy production and conversion:Predicted Fe-S oxidoreductases:MoxR-like ATPases:ABC-type multidrug transport system, ATPase component:Transcriptional regulators:Heme/copper-type cytochrome/quinol oxidase, subunit 3:Cytochrome c, mono- and diheme variants:Nitric oxide reductase large subunit:Nitrous oxidase accessory protein:Regulator of nitric oxide reductase transcription:Nitrous oxide reductase:Nitric oxide reductase activation protein:Transcription:Inorganic ion transport and metabolism:Nitrogen metabolism:Microbial metabolism in diverse environments:General function prediction only:TAT_signal_seq:para_beta_helix:rSAM_NirJ:Defense mechanisms:Poorly characterized:Energy Metabolism:Global:Metabolism:Protein fate:Protein and peptide secretion and trafficking:Biosynthesis of cofactors, prosthetic groups, and carriers:Heme, porphyrin, and cobalamin:Information storage and processing:Cellular processes and signaling:Metabolism:Metabolism" 459 "Energy production and conversion:Glutamine synthetase:Glycosyltransferase:Transcriptional regulator:Signal transduction histidine kinase:Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs:Uncharacterized low-complexity proteins:Pyridoxal phosphate biosynthesis protein:Cytochrome c, mono- and diheme variants:Sugar phosphate permease:ATP-dependent transcriptional regulator:Uncharacterized protein conserved in bacteria:Uncharacterized conserved protein:Uncharacterized protein conserved in bacteria:Predicted metal-dependent hydrolase of the TIM-barrel fold:Glucose dehydrogenase:Uncharacterized conserved protein:Amino acid transport and metabolism:Carbohydrate transport and metabolism:Coenzyme transport and metabolism:Transcription:Cell wall/membrane/envelope biogenesis:Glycolysis / Gluconeogenesis:Alanine aspartate and glutamate metabolism:Arginine and proline metabolism:Chloroalkane and chloroalkene degradation:Propanoate metabolism:Vitamin B6 metabolism:Nitrogen metabolism:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:Two-component system:General function prediction only:Function unknown:Signal transduction mechanisms:sensory_box:PQQ_enz_alc_DH:Metabolism:Cellular processes and signaling:Information storage and processing:Small molecule interactions:Regulatory functions:Metabolism:Metabolism:Global:Signal Transduction:Environmental Information Processing:Xenobiotics Biodegradation and Metabolism:Metabolism of Cofactors and Vitamins:Amino Acid Metabolism:Energy Metabolism:Poorly characterized:Carbohydrate Metabolism" 460 "Phosphoglycerate dehydrogenase and related dehydrogenases:RecA/RadA recombinase:ATPase involved in DNA repair:Protein chain release factor B:Transcriptional regulator:Uncharacterized conserved protein:Transcriptional regulators:SOS-response transcriptional repressors (RecA-mediated autopeptidases):Uncharacterized protein conserved in bacteria:Mg/Co/Ni transporter MgtE (contains CBS domain):Uncharacterized protein conserved in bacteria:SOS-response cell division inhibitor, blocks FtsZ ring formation:Cell cycle control, cell division, chromosome partitioning:Amino acid transport and metabolism:Coenzyme transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:Replication, recombination and repair:Inorganic ion transport and metabolism:Aminoacyl-tRNA biosynthesis:Homologous recombination:General function prediction only:Function unknown:Signal transduction mechanisms:mgtE:lexA:recN:tigrfam_recA:release_prfH:release_rtcB:Poorly characterized:Metabolism:Cellular processes and signaling:Information storage and processing:Cations and iron carrying compounds:Transport and binding proteins:Translation factors:Other:Protein synthesis:DNA replication, recombination, and repair:DNA metabolism:DNA interactions:Regulatory functions:Genetic Information Processing:Replication and Repair:Translation" 461 "Energy production and conversion:Acetyltransferases:Selenocysteine lyase:Transcriptional regulator:Sulfate permease and related transporters (MFS superfamily):Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases):Uncharacterized conserved protein:Flagellar biosynthesis pathway, component FlhB:Phosphatidylserine/phosphatidylglycerophosphate/cardiolipin synthases and related enzymes:Acetyltransferases, including N-acetylases of ribosomal proteins:Flagellar biosynthesis pathway, component FliR:Predicted acyl-CoA transferases/carnitine dehydratase:FOG: GGDEF domain:AraC-type DNA-binding domain-containing proteins:Putative NADPH-quinone reductase (modulator of drug activity B):Predicted permeases:Negative regulator of beta-lactamase expression:Arylsulfatase A and related enzymes:Uncharacterized protein conserved in bacteria:Uncharacterized conserved protein:P pilus assembly protein, pilin FimA:Membrane protein required for beta-lactamase induction:Uncharacterized conserved protein:Uncharacterized protein conserved in bacteria:Amino acid transport and metabolism:Lipid transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:Cell motility:Inorganic ion transport and metabolism:Aminoacyl-tRNA biosynthesis:Flagellar assembly:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:Function unknown:Signal transduction mechanisms:GGDEF:flhB:fliR:chol_sulfatase:Intracellular trafficking, secretion, and vesicular transport:Defense mechanisms:Translation:Genetic Information Processing:Poorly characterized:Metabolism:Cellular processes and signaling:Information storage and processing:Other:Signal transduction:Chemotaxis and motility:Cellular processes:Cell Motility:Cellular Processes" 462 "Energy production and conversion:Glutathione synthase/Ribosomal protein S6 modification enzyme (glutaminyl transferase):Ribonucleotide reductase, alpha subunit:dGTP triphosphohydrolase:Malic enzyme:Guanosine polyphosphate pyrophosphohydrolases/synthetases:Predicted ATPase:Isocitrate/isopropylmalate dehydrogenase:Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily):NADPH:quinone reductase and related Zn-dependent oxidoreductases:Glutathione S-transferase:Methyl-accepting chemotaxis protein:Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs:Isopentenyldiphosphate isomerase:D-Tyr-tRNAtyr deacylase:Outer membrane receptor proteins, mostly Fe transport:Electron transfer flavoprotein, beta subunit:Uncharacterized protein conserved in bacteria:Rhodanese-related sulfurtransferase:Uncharacterized enzyme of heme biosynthesis:Predicted oxidoreductase related to nitroreductase:Uncharacterized protein related to arylsulfate sulfotransferase involved in siderophore biosynthesis:Amino acid transport and metabolism:Nucleotide transport and metabolism:Coenzyme transport and metabolism:Lipid transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:Cell motility:Posttranslational modification, protein turnover, chaperones:Inorganic ion transport and metabolism:Purine metabolism:Pyrimidine metabolism:Cysteine and methionine metabolism:Valine leucine and isoleucine biosynthesis:Arginine and proline metabolism:Glutathione metabolism:Pyruvate metabolism:Metabolic pathways:Biosynthesis of secondary metabolites:Two-component system:Sulfur relay system:General function prediction only:Function unknown:Signal transduction mechanisms:leuB:TIGR00256:spoT_relA:pro_imino_pep_1:dGTP_triPase:glut_syn:TonB-copper:NrdJ_Z:AZL_007950_fam:Pyruvate family:Carbohydrate Metabolism:Nucleotide Metabolism:Amino Acid Metabolism:Metabolism of Other Amino Acids:Genetic Information Processing:Folding Sorting and Degradation:Environmental Information Processing:Signal Transduction:Global:Metabolism:Purines, pyrimidines, nucleosides, and nucleotides:Nucleotide and nucleoside interconversions:2'-Deoxyribonucleotide metabolism:Protein synthesis:tRNA aminoacylation:Transport and binding proteins:Porins:Cellular processes:Adaptations to atypical conditions:Amino acid biosynthesis:Metabolism:Biosynthesis of cofactors, prosthetic groups, and carriers:Glutathione and analogs:Information storage and processing:Cellular processes and signaling:Metabolism:Poorly characterized" 463 "Energy production and conversion:Acetyl-CoA acetyltransferase:Glycosyltransferases involved in cell wall biogenesis:Na+-driven multidrug efflux pump:Transcriptional regulator:Predicted thioesterase:Enoyl-CoA hydratase/carnithine racemase:Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases):3-hydroxyacyl-CoA dehydrogenase:Lysine efflux permease:Alcohol dehydrogenase, class IV:Predicted acyl-CoA transferases/carnitine dehydratase:4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family:Acyl-CoA dehydrogenases:Predicted membrane protein:Sugar phosphate permease:Uncharacterized protein conserved in bacteria:Uncharacterized protein conserved in bacteria:Carbohydrate transport and metabolism:Lipid transport and metabolism:Transcription:Cell wall/membrane/envelope biogenesis:Fructose and mannose metabolism:Fatty acid biosynthesis:Fatty acid metabolism:Synthesis and degradation of ketone bodies:Valine leucine and isoleucine degradation:Geraniol degradation:Lysine degradation:Benzoate degradation:Bisphenol degradation:Tryptophan metabolism:beta-Alanine metabolism:Pyruvate metabolism:Chloroalkane and chloroalkene degradation:Aminobenzoate degradation:Glyoxylate and dicarboxylate metabolism:Propanoate metabolism:Butanoate metabolism:Carbon fixation pathways in prokaryotes:Terpenoid backbone biosynthesis:Limonene and pinene degradation:Caprolactam degradation:Biosynthesis of unsaturated fatty acids:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:Two-component system:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:Function unknown:matE:AcCoA-C-Actrans:Defense mechanisms:Fatty acid and phospholipid metabolism:Metabolism:Metabolism:Global:Signal Transduction:Environmental Information Processing:Xenobiotics Biodegradation and Metabolism:Metabolism of Terpenoids and Polyketides:Metabolism of Other Amino Acids:Amino Acid Metabolism:Lipid Metabolism:Energy Metabolism:Poorly characterized:Carbohydrate Metabolism:Metabolism:Cellular processes and signaling:Information storage and processing:Other:Transport and binding proteins:Other" 464 "Xanthosine triphosphate pyrophosphatase:ATP-dependent Lon protease, bacterial type:Rhodanese-related sulfurtransferase:N-acetylmuramoyl-L-alanine amidase:dTDP-4-dehydrorhamnose reductase:dTDP-glucose pyrophosphorylase:ATP-dependent protease Clp, ATPase subunit:dTDP-4-dehydrorhamnose 3,5-epimerase and related enzymes:Predicted acyltransferase:Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains:Uncharacterized protein affecting Mg2+/Co2+ transport:Kynureninase:Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain:Amino acid transport and metabolism:Nucleotide transport and metabolism:Cell wall/membrane/envelope biogenesis:Posttranslational modification, protein turnover, chaperones:Inorganic ion transport and metabolism:Purine metabolism:Tryptophan metabolism:Streptomycin biosynthesis:Polyketide sugar unit biosynthesis:Thiamine metabolism:Metabolic pathways:Biosynthesis of secondary metabolites:Two-component system:General function prediction only:Signal transduction mechanisms:TIGR00042:GGDEF:clpX:apaH:lon:rmlA:rmlD:rmlC:kynureninase:ntrC:Other:Cell envelope:Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides:Cellular processes and signaling:Metabolism:Poorly characterized:Cellular processes:Degradation of proteins, peptides, and glycopeptides:Protein fate:DNA replication, recombination, and repair:DNA metabolism:Amino acids and amines:Energy metabolism:Metabolism:Metabolism:Global:Signal Transduction:Environmental Information Processing:Biosynthesis of Other Secondary Metabolites:Metabolism of Terpenoids and Polyketides:Metabolism of Cofactors and Vitamins:Amino Acid Metabolism:Adaptations to atypical conditions:Nucleotide Metabolism:Signal transduction:Two-component systems" 465 "Energy production and conversion:Fumarase:Predicted divalent heavy-metal cations transporter:Superoxide dismutase:DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog:AraC-type DNA-binding domain-containing proteins:Precorrin-6B methylase 2:Siderophore-interacting protein:Heme oxygenase:Fe2+-dicitrate sensor, membrane component:Coenzyme transport and metabolism:Transcription:Inorganic ion transport and metabolism:Citrate cycle (TCA cycle):Carbon fixation pathways in prokaryotes:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:RNA polymerase:Signal transduction mechanisms:sigma70-ECF:Cellular processes and signaling:Carbohydrate Metabolism:Energy Metabolism:Genetic Information Processing:Transcription:Global:Metabolism:Information storage and processing:Metabolism:Metabolism" 466 "Energy production and conversion:Fe-S oxidoreductase:ABC-type branched-chain amino acid transport systems, ATPase component:Uncharacterized NAD(FAD)-dependent dehydrogenases:Branched-chain amino acid ABC-type transport system, permease components:Glycine/D-amino acid oxidases (deaminating):Formyltetrahydrofolate hydrolase:Flavodoxin reductases (ferredoxin-NADPH reductases) family 1:Threonine dehydrogenase and related Zn-dependent dehydrogenases:NADH:flavin oxidoreductases, Old Yellow Enzyme family:Electron transfer flavoprotein, alpha subunit:Electron transfer flavoprotein, beta subunit:ABC-type proline/glycine betaine transport systems, periplasmic components:Zn-dependent dipeptidase, microsomal dipeptidase homolog:Predicted enzyme of the cupin superfamily:Sarcosine oxidase delta subunit:Sarcosine oxidase gamma subunit:Phenylpropionate dioxygenase and related ring-hydroxylating dioxygenases, large terminal subunit:Amino acid transport and metabolism:Nucleotide transport and metabolism:Inorganic ion transport and metabolism:Glycine serine and threonine metabolism:Chloroalkane and chloroalkene degradation:Glyoxylate and dicarboxylate metabolism:One carbon pool by folate:Methane metabolism:Metabolic pathways:Microbial metabolism in diverse environments:ABC transporters:General function prediction only:soxA:soxB:soxD:soxG:fdhA_non_GSH:Energy metabolism:One-carbon metabolism:Central intermediary metabolism:Metabolism:Metabolism:Global:Membrane Transport:Environmental Information Processing:Xenobiotics Biodegradation and Metabolism:Metabolism of Cofactors and Vitamins:Amino Acid Metabolism:Energy Metabolism:Poorly characterized:Carbohydrate Metabolism:Metabolism:Amino acids and amines" 467 "Energy production and conversion:Succinyl-CoA synthetase, beta subunit:Succinyl-CoA synthetase, alpha subunit:Citrate synthase:Succinate dehydrogenase/fumarate reductase, Fe-S protein subunit:Uncharacterized protein conserved in bacteria:Biopolymer transport proteins:Periplasmic component of the Tol biopolymer transport system:Biopolymer transport protein:Succinate dehydrogenase/fumarate reductase, flavoprotein subunit:Succinate dehydrogenase/fumarate reductase, cytochrome b subunit:Succinate dehydrogenase, hydrophobic anchor subunit:Monomeric isocitrate dehydrogenase:Citrate cycle (TCA cycle):Oxidative phosphorylation:Glutathione metabolism:Toluene degradation:Glyoxylate and dicarboxylate metabolism:Propanoate metabolism:Butanoate metabolism:C5-Branched dibasic acid metabolism:Carbon fixation pathways in prokaryotes:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:Function unknown:DNA_YbaB_EbfC:monomer_idh:dhsB:sucCoAbeta:sucCoAalpha:cit_synth_I:sdhA_frdA_Gneg:tolQ:propeller_TolB:tolR:succ_dehyd_anc:succ_dehyd_cytB:Intracellular trafficking, secretion, and vesicular transport:Poorly characterized:Pathogenesis:Cellular processes:TCA cycle:Energy metabolism:Metabolism:Metabolism:Global:Xenobiotics Biodegradation and Metabolism:Metabolism of Other Amino Acids:Energy Metabolism:Unknown function:Carbohydrate Metabolism:General:Cellular processes and signaling:Metabolism" 468 "Glutamate-1-semialdehyde aminotransferase:Glutamine synthetase:Nucleotidyltransferase/DNA polymerase involved in DNA repair:RecA/RadA recombinase:ATPase involved in DNA repair:Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases):Transcriptional regulator:Transcriptional regulators:Phage shock protein A (IM30), suppresses sigma54-dependent transcription:SOS-response transcriptional repressors (RecA-mediated autopeptidases):Uncharacterized protein conserved in bacteria:Predicted transcriptional regulator:Uncharacterized protein conserved in bacteria:Uncharacterized protein conserved in bacteria:Uncharacterized conserved protein:SOS-response cell division inhibitor, blocks FtsZ ring formation:Cell cycle control, cell division, chromosome partitioning:Amino acid transport and metabolism:Coenzyme transport and metabolism:Lipid transport and metabolism:Transcription:Replication, recombination and repair:Fatty acid biosynthesis:Alanine aspartate and glutamate metabolism:Arginine and proline metabolism:Porphyrin and chlorophyll metabolism:Nitrogen metabolism:Aminoacyl-tRNA biosynthesis:Biosynthesis of unsaturated fatty acids:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:Two-component system:Homologous recombination:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:Function unknown:Signal transduction mechanisms:lexA:recN:tigrfam_recA:Metabolism:Global:Signal Transduction:Environmental Information Processing:Replication and Repair:Translation:Genetic Information Processing:Metabolism of Cofactors and Vitamins:Amino Acid Metabolism:Lipid Metabolism:Cellular processes and signaling:Energy Metabolism:Metabolism:Poorly characterized:Information storage and processing:DNA replication, recombination, and repair:DNA metabolism:DNA interactions:Regulatory functions:Metabolism" 469 "Glucose-6-phosphate 1-dehydrogenase:Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases:Glycosyltransferase:Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases:Transcriptional regulator:Uncharacterized enzymes related to aldose 1-epimerase:Membrane proteins related to metalloendopeptidases:Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain:ADP-ribose pyrophosphatase:D-alanine-D-alanine ligase and related ATP-grasp enzymes:Predicted membrane protein, hemolysin III homolog:Transcriptional regulator:Transcriptional regulators:Dioxygenases related to 2-nitropropane dioxygenase:Uncharacterized protein conserved in bacteria:Beta-lactamase class D:Rhodanese-related sulfurtransferase:Uncharacterized protein conserved in bacteria:Predicted ATPase/kinase involved in NAD metabolism:Uncharacterized protein conserved in bacteria:Transcriptional antiterminator:Inhibitor of the KinA pathway to sporulation, predicted exonuclease:Predicted metal-dependent enzyme of the double-stranded beta helix superfamily:Nucleotide transport and metabolism:Carbohydrate transport and metabolism:Coenzyme transport and metabolism:Lipid transport and metabolism:Transcription:Cell wall/membrane/envelope biogenesis:Inorganic ion transport and metabolism:Glycolysis / Gluconeogenesis:Pentose phosphate pathway:Penicillin and cephalosporin biosynthesis:D-Alanine metabolism:Glutathione metabolism:Peptidoglycan biosynthesis:Butanoate metabolism:Nitrogen metabolism:Aminoacyl-tRNA biosynthesis:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:Two-component system:General function prediction only:Function unknown:Signal transduction mechanisms:zwf:hlyIII:D_ala_D_alaTIGR:ac_ac_CoA_syn:Defense mechanisms:Metabolism:Cellular processes and signaling:Information storage and processing:Biosynthesis and degradation of murein sacculus and peptidoglycan:Cell envelope:Pentose phosphate pathway:Energy metabolism:Other:Central intermediary metabolism:Metabolism:Metabolism:Global:Signal Transduction:Environmental Information Processing:Translation:Genetic Information Processing:Biosynthesis of Other Secondary Metabolites:Glycan Biosynthesis and Metabolism:Metabolism of Other Amino Acids:Energy Metabolism:Carbohydrate Metabolism:Poorly characterized" 470 "Energy production and conversion:Fe-S oxidoreductase:ABC-type branched-chain amino acid transport systems, ATPase component:ABC-type branched-chain amino acid transport systems, ATPase component:Uncharacterized NAD(FAD)-dependent dehydrogenases:Branched-chain amino acid ABC-type transport system, permease components:Glycine/D-amino acid oxidases (deaminating):Formyltetrahydrofolate hydrolase:DNA polymerase III, epsilon subunit and related 3'-5' exonucleases:Flavodoxin reductases (ferredoxin-NADPH reductases) family 1:Predicted exporters of the RND superfamily:Threonine dehydrogenase and related Zn-dependent dehydrogenases:TRAP-type C4-dicarboxylate transport system, large permease component:L-serine deaminase:NADH:flavin oxidoreductases, Old Yellow Enzyme family:Electron transfer flavoprotein, alpha subunit:Electron transfer flavoprotein, beta subunit:ABC-type proline/glycine betaine transport systems, periplasmic components:Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain:Zn-dependent dipeptidase, microsomal dipeptidase homolog:Predicted signal-transduction protein containing cAMP-binding and CBS domains:TRAP-type C4-dicarboxylate transport system, small permease component:Predicted enzyme of the cupin superfamily:ABC-type branched-chain amino acid transport system, permease component:Sarcosine oxidase delta subunit:Uncharacterized protein related to plant photosystem II stability/assembly factor:Sarcosine oxidase gamma subunit:Phenylpropionate dioxygenase and related ring-hydroxylating dioxygenases, large terminal subunit:Amino acid transport and metabolism:Nucleotide transport and metabolism:Carbohydrate transport and metabolism:Transcription:Replication, recombination and repair:Inorganic ion transport and metabolism:Purine metabolism:Pyrimidine metabolism:Glycine serine and threonine metabolism:Cysteine and methionine metabolism:Chloroalkane and chloroalkene degradation:Glyoxylate and dicarboxylate metabolism:One carbon pool by folate:Methane metabolism:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:ABC transporters:Two-component system:DNA replication:Mismatch repair:Homologous recombination:General function prediction only:Signal transduction mechanisms:sda_mono:dctM:soxA:soxB:soxD:soxG:fdhA_non_GSH:Carbohydrates, organic alcohols, and acids:Transport and binding proteins:Glycolysis/gluconeogenesis:Amino acids and amines:Energy metabolism:One-carbon metabolism:Central intermediary metabolism:Metabolism:Metabolism:Global:Signal Transduction:Membrane Transport:Environmental Information Processing:Replication and Repair:Genetic Information Processing:Xenobiotics Biodegradation and Metabolism:Metabolism of Cofactors and Vitamins:Amino Acid Metabolism:Nucleotide Metabolism:Energy Metabolism:Poorly characterized:Carbohydrate Metabolism:Metabolism:Cellular processes and signaling:Information storage and processing" 471 "Energy production and conversion:Acetyl-CoA acetyltransferase:Predicted phosphatase/phosphohexomutase:2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases:Predicted dehydrogenases and related proteins:Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases):Sugar phosphate isomerases/epimerases:Acyl CoA:acetate/3-ketoacid CoA transferase, alpha subunit:Acyl-CoA dehydrogenases:Acyl CoA:acetate/3-ketoacid CoA transferase, beta subunit:Long-chain fatty acid transport protein:Sugar phosphate permease:P pilus assembly protein, chaperone PapD:P pilus assembly protein, porin PapC:Uncharacterized protein conserved in bacteria:Tfp pilus assembly protein FimT:Carbohydrate transport and metabolism:Coenzyme transport and metabolism:Lipid transport and metabolism:Cell motility:Fatty acid metabolism:Valine leucine and isoleucine degradation:Benzoate degradation:beta-Alanine metabolism:Propanoate metabolism:Styrene degradation:Butanoate metabolism:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:Function unknown:2A0115:AcCoA-C-Actrans:pbenz_hydroxyl:IV_pilin_GFxxxE:Intracellular trafficking, secretion, and vesicular transport:Poorly characterized:Metabolism:Cellular processes and signaling:Carbohydrates, organic alcohols, and acids:Transport and binding proteins:Protein and peptide secretion and trafficking:Protein fate:Other:Fatty acid and phospholipid metabolism:Other:Energy metabolism:Metabolism:Metabolism:Global:Xenobiotics Biodegradation and Metabolism:Metabolism of Other Amino Acids:Amino Acid Metabolism:Lipid Metabolism:Carbohydrate Metabolism" 472 "Isopropylmalate/homocitrate/citramalate synthases:Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II:Asparagine synthase (glutamine-hydrolyzing):Predicted phosphatase/phosphohexomutase:Membrane proteins related to metalloendopeptidases:Predicted glycosyltransferases:Uncharacterized conserved protein:Outer membrane protein:Multidrug resistance efflux pump:Predicted metal-dependent hydrolase with the TIM-barrel fold:Uncharacterized conserved protein, contains double-stranded beta-helix domain:Predicted carbamoyl transferase, NodU family:Na+/melibiose symporter and related transporters:Arabinose efflux permease:Uncharacterized protein conserved in bacteria:Amino acid transport and metabolism:Carbohydrate transport and metabolism:Lipid transport and metabolism:Cell wall/membrane/envelope biogenesis:Posttranslational modification, protein turnover, chaperones:Valine leucine and isoleucine biosynthesis:Pyruvate metabolism:Aminoacyl-tRNA biosynthesis:Metabolic pathways:Biosynthesis of secondary metabolites:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:Function unknown:HAD-SF-IA-v3:rhamnosyltran:type_I_hlyD:type_I_sec_TolC:Intracellular trafficking, secretion, and vesicular transport:Defense mechanisms:Poorly characterized:Carbohydrate Metabolism:Amino Acid Metabolism:Genetic Information Processing:Translation:Global:Metabolism:Protein fate:Protein and peptide secretion and trafficking:Transport and binding proteins:Porins:Unknown function:Enzymes of unknown specificity:Cell envelope:Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides:Cellular processes and signaling:Metabolism:Metabolism" 473 "Energy production and conversion:Ammonia permease:Adenosylmethionine-8-amino-7-oxononanoate aminotransferase:Sulfite reductase, alpha subunit (flavoprotein):NADPH:quinone reductase and related Zn-dependent oxidoreductases:FOG: TPR repeat, SEL1 subfamily:Outer membrane protein:Multidrug resistance efflux pump:Transcriptional regulators:Multiple antibiotic transporter:Methylase involved in ubiquinone/menaquinone biosynthesis:ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain:Protein related to penicillin acylase:Sterol desaturase:Uncharacterized iron-regulated protein:P pilus assembly protein, porin PapC:Uncharacterized protein conserved in bacteria:Outer membrane receptor for monomeric catechols:Uncharacterized secreted protein:Coenzyme transport and metabolism:Lipid transport and metabolism:Transcription:Cell wall/membrane/envelope biogenesis:Cell motility:Inorganic ion transport and metabolism:Penicillin and cephalosporin biosynthesis:Sulfur metabolism:Aminoacyl-tRNA biosynthesis:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:ABC transporters:General function prediction only:Function unknown:TIGR00427:efflux_EmrB:vgr_GE:TonB-siderophor:outer_NodT:Intracellular trafficking, secretion, and vesicular transport:Defense mechanisms:Global:Membrane Transport:Environmental Information Processing:Translation:Genetic Information Processing:Biosynthesis of Other Secondary Metabolites:Poorly characterized:Energy Metabolism:Metabolism:Cellular processes and signaling:Information storage and processing:General:Unknown function:Porins:Other:Transport and binding proteins:Metabolism:Metabolism" 474 "Predicted ATPase of the PP-loop superfamily implicated in cell cycle control:tRNA-dihydrouridine synthase:Triosephosphate isomerase:Biotin-(acetyl-CoA carboxylase) ligase:DNA primase (bacterial type):tmRNA-binding protein:ABC-type transport system involved in resistance to organic solvents, permease component:Actin-like ATPase involved in cell morphogenesis:ABC-type transport system involved in resistance to organic solvents, ATPase component:ABC-type metal ion transport system, ATPase component:Putative transcriptional regulator, homolog of Bvg accessory factor:Uncharacterized conserved protein:Factor for inversion stimulation Fis, transcriptional activator:Uncharacterized protein conserved in bacteria:Cell cycle control, cell division, chromosome partitioning:Carbohydrate transport and metabolism:Coenzyme transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:Replication, recombination and repair:Posttranslational modification, protein turnover, chaperones:Inorganic ion transport and metabolism:Glycolysis / Gluconeogenesis:Fructose and mannose metabolism:Inositol phosphate metabolism:Pantothenate and CoA biosynthesis:Biotin metabolism:Aminoacyl-tRNA biosynthesis:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:ABC transporters:Ribosome:DNA replication:Secondary metabolites biosynthesis, transport and catabolism:Function unknown:TIGR00056:smpB:birA_ligase:tim:baf:nifR3_yhdG:mreB:dnaG:Information storage and processing:Carbohydrate Metabolism:Metabolism of Cofactors and Vitamins:Genetic Information Processing:Translation:Replication and Repair:Environmental Information Processing:Membrane Transport:Global:Metabolism:Energy metabolism:Glycolysis/gluconeogenesis:DNA metabolism:DNA replication, recombination, and repair:Protein synthesis:Other:Protein fate:Protein modification and repair:Hypothetical proteins:Conserved:Unknown function:General:Biosynthesis of cofactors, prosthetic groups, and carriers:Pantothenate and coenzyme A:Cell envelope:Biosynthesis and degradation of murein sacculus and peptidoglycan:Metabolism:Cellular processes and signaling:Metabolism:Poorly characterized" 475 "Energy production and conversion:Ammonia permease:Uncharacterized NAD(FAD)-dependent dehydrogenases:Acetyltransferases:GMP synthase - Glutamine amidotransferase domain:Glycerophosphoryl diester phosphodiesterase:Aldo/keto reductases, related to diketogulonate reductase:Membrane carboxypeptidase (penicillin-binding protein):Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases):Membrane-bound serine protease (ClpP class):Threonine dehydratase:NADH dehydrogenase, FAD-containing subunit:ABC-type sugar transport system, periplasmic component:Predicted transcriptional regulators:DNA/RNA endonuclease G, NUC1:HD-GYP domain:Predicted Zn-dependent hydrolases of the beta-lactamase fold:Putative NADH-flavin reductase:O-Methyltransferase involved in polyketide biosynthesis:ABC-type sugar transport systems, ATPase components:Uncharacterized protein conserved in bacteria:Flp pilus assembly protein TadB:Amino acid transport and metabolism:Nucleotide transport and metabolism:Carbohydrate transport and metabolism:Lipid transport and metabolism:Transcription:Cell wall/membrane/envelope biogenesis:Posttranslational modification, protein turnover, chaperones:Inorganic ion transport and metabolism:Fatty acid biosynthesis:Oxidative phosphorylation:Glycine serine and threonine metabolism:Valine leucine and isoleucine biosynthesis:Glycerophospholipid metabolism:Biosynthesis of unsaturated fatty acids:Metabolic pathways:Biosynthesis of secondary metabolites:ABC transporters:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:Function unknown:Signal transduction mechanisms:HDIG:Intracellular trafficking, secretion, and vesicular transport:Cellular processes and signaling:Information storage and processing:Metabolism:Global:Membrane Transport:Environmental Information Processing:Amino Acid Metabolism:Lipid Metabolism:Metabolism:Energy Metabolism:Poorly characterized:Metabolism" 476 "Predicted ATPase of the PP-loop superfamily implicated in cell cycle control:Uncharacterized low-complexity proteins:Predicted acyltransferases:Protein involved in cell division:Predicted ATP-dependent endonuclease of the OLD family:Chain length determinant protein:Superfamily I DNA and RNA helicases:Uncharacterized conserved protein:Cell cycle control, cell division, chromosome partitioning:Lipid transport and metabolism:Replication, recombination and repair:Cell wall/membrane/envelope biogenesis:General function prediction only:Function unknown:DOC_P1:WbuX:Metabolism:Cellular processes and signaling:Information storage and processing:General:Unknown function:Poorly characterized" 477 "Energy production and conversion:Predicted sugar kinase:3-isopropylmalate dehydratase large subunit:3-isopropylmalate dehydratase small subunit:Anthranilate/para-aminobenzoate synthases component I:Nicotinate-nucleotide pyrophosphorylase:Protoheme ferro-lyase (ferrochelatase):Carbonic anhydrase:Anthranilate phosphoribosyltransferase:Transcriptional regulator:Dehydrogenases (flavoproteins):Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain:Transcription elongation factor:Transcriptional regulators:Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain:Predicted membrane protein:Uncharacterized protein conserved in bacteria:Uncharacterized protein conserved in bacteria:Uncharacterized protein conserved in bacteria:Uncharacterized protein conserved in archaea:Signal transduction histidine kinase:Amino acid transport and metabolism:Carbohydrate transport and metabolism:Coenzyme transport and metabolism:Transcription:Posttranslational modification, protein turnover, chaperones:Inorganic ion transport and metabolism:Valine leucine and isoleucine biosynthesis:Phenylalanine tyrosine and tryptophan biosynthesis:Lipopolysaccharide biosynthesis:C5-Branched dibasic acid metabolism:Nicotinate and nicotinamide metabolism:Porphyrin and chlorophyll metabolism:Nitrogen metabolism:Aminoacyl-tRNA biosynthesis:Metabolic pathways:Biosynthesis of secondary metabolites:Two-component system:Function unknown:Signal transduction mechanisms:nadC:hemH:leuC:leuD:trpE_most:trpD:greA:lipid_A_lpxH:PhoB:phoR_proteo:Aromatic amino acid family:Amino acid biosynthesis:Transcription factors:Transcription:Metabolism:Global:Metabolism:Signal Transduction:Environmental Information Processing:Translation:Genetic Information Processing:Metabolism of Cofactors and Vitamins:Glycan Biosynthesis and Metabolism:Amino Acid Metabolism:Energy Metabolism:Biosynthesis of cofactors, prosthetic groups, and carriers:Carbohydrate Metabolism:Heme, porphyrin, and cobalamin:Pyridine nucleotides:Signal transduction:Two-component systems:Cell envelope:Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides:Information storage and processing:Cellular processes and signaling:Metabolism:Poorly characterized:Pyruvate family" 478 "Energy production and conversion:DNA mismatch repair enzyme (predicted ATPase):tRNA delta(2)-isopentenylpyrophosphate transferase:Recombinational DNA repair protein (RecF pathway):Superfamily II DNA helicase:Signal transduction histidine kinase:Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains):Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain:Bacterial cell division membrane protein:Enoyl-CoA hydratase/carnithine racemase:Adenylate cyclase, family 3 (some proteins contain HAMP domain):Cell division protein:NTP pyrophosphohydrolases containing a Zn-finger, probably nucleic-acid-binding:Na+/H+ antiporter:Predicted membrane protein:ABC-type phosphate/phosphonate transport system, ATPase component:ATP phosphoribosyltransferase involved in histidine biosynthesis:Predicted NADH:ubiquinone oxidoreductase, subunit RnfA:Cell cycle control, cell division, chromosome partitioning:Amino acid transport and metabolism:Lipid transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:Replication, recombination and repair:Cell wall/membrane/envelope biogenesis:Inorganic ion transport and metabolism:Fatty acid metabolism:Valine leucine and isoleucine degradation:Geraniol degradation:Lysine degradation:Histidine metabolism:Benzoate degradation:Tryptophan metabolism:beta-Alanine metabolism:Aminobenzoate degradation:Propanoate metabolism:Butanoate metabolism:Methane metabolism:Nicotinate and nicotinamide metabolism:Limonene and pinene degradation:Caprolactam degradation:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:ABC transporters:RNA degradation:Mismatch repair:Homologous recombination:Function unknown:Signal transduction mechanisms:miaA:hisZ_biosyn_reg:mutl:recQ_fam:recR:rnfA:rodA_shape:Amino acid biosynthesis:Carbohydrate Metabolism:Energy Metabolism:Lipid Metabolism:Amino Acid Metabolism:Metabolism of Other Amino Acids:Metabolism of Cofactors and Vitamins:Metabolism of Terpenoids and Polyketides:Xenobiotics Biodegradation and Metabolism:Genetic Information Processing:Folding Sorting and Degradation:Replication and Repair:Environmental Information Processing:Membrane Transport:Global:Metabolism:Energy metabolism:Electron transport:DNA metabolism:DNA replication, recombination, and repair:Protein synthesis:tRNA and rRNA base modification:Cellular processes:Cell division:Metabolism:Histidine family:Information storage and processing:Cellular processes and signaling:Metabolism:Poorly characterized" 479 "Signal transduction histidine kinase:Putative intracellular protease/amidase:Predicted redox protein, regulator of disulfide bond formation:Formate/nitrite family of transporters:Glucose/sorbosone dehydrogenases:Putative NADH-flavin reductase:Predicted membrane protein:Carbohydrate transport and metabolism:Posttranslational modification, protein turnover, chaperones:Inorganic ion transport and metabolism:General function prediction only:Function unknown:Signal transduction mechanisms:sensory_box:PfpI:osmo_induc_OsmC:Cellular processes and signaling:Detoxification:Cellular processes:Degradation of proteins, peptides, and glycopeptides:Protein fate:Small molecule interactions:Regulatory functions:Metabolism:Poorly characterized" 480 "Nuclease subunit of the excinuclease complex:Acetyltransferases:dUTPase:Membrane protein TerC, possibly involved in tellurium resistance:RecG-like helicase:Aspartyl aminopeptidase:4-diphosphocytidyl-2C-methyl-D-erythritol 2-phosphate synthase:Predicted peroxiredoxins:Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains:Uncharacterized protein conserved in bacteria:Glycerol-3-phosphate O-acyltransferase:ABC-type uncharacterized transport system, periplasmic component:Signal transduction histidine kinase regulating citrate/malate metabolism:Signal transduction histidine kinase, nitrogen specific:Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain:Amino acid transport and metabolism:Nucleotide transport and metabolism:Lipid transport and metabolism:Transcription:Replication, recombination and repair:Inorganic ion transport and metabolism:Pyrimidine metabolism:Glycerolipid metabolism:Glycerophospholipid metabolism:Terpenoid backbone biosynthesis:Aminoacyl-tRNA biosynthesis:Metabolic pathways:Biosynthesis of secondary metabolites:Two-component system:Nucleotide excision repair:Homologous recombination:General function prediction only:Function unknown:Signal transduction mechanisms:ispE:uvrC:sensory_box:dut:recG:plsB:Poorly characterized:Lipid Metabolism:Nucleotide Metabolism:Metabolism of Terpenoids and Polyketides:Genetic Information Processing:Translation:Replication and Repair:Environmental Information Processing:Signal Transduction:Global:Metabolism:Fatty acid and phospholipid metabolism:Biosynthesis:Purines, pyrimidines, nucleosides, and nucleotides:2'-Deoxyribonucleotide metabolism:Regulatory functions:Small molecule interactions:DNA metabolism:DNA replication, recombination, and repair:Biosynthesis of cofactors, prosthetic groups, and carriers:Other:Information storage and processing:Cellular processes and signaling:Metabolism:Metabolism" 481 "Energy production and conversion:Arginase/agmatinase/formimionoglutamate hydrolase, arginase family:Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit:Dihydroorotase and related cyclic amidohydrolases:Dihydroorotate dehydrogenase:NADPH-dependent glutamate synthase beta chain and related oxidoreductases:Na+/proline symporter:Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily):Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases:Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases):Threonine dehydrogenase and related Zn-dependent dehydrogenases:Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit:Uncharacterized ABC-type transport system, permease component:Metal-dependent amidase/aminoacylase/carboxypeptidase:Cytosine/uracil/thiamine/allantoin permeases:Uncharacterized conserved protein:Predicted amino acid aldolase or racemase:ABC-type uncharacterized transport systems, ATPase components:ABC-type uncharacterized transport system, permease component:Amino acid transport and metabolism:Nucleotide transport and metabolism:Coenzyme transport and metabolism:Lipid transport and metabolism:Glycolysis / Gluconeogenesis:Citrate cycle (TCA cycle):Pyrimidine metabolism:Alanine aspartate and glutamate metabolism:Valine leucine and isoleucine biosynthesis:Arginine and proline metabolism:Phenylalanine metabolism:beta-Alanine metabolism:Pyruvate metabolism:Butanoate metabolism:Pantothenate and CoA biosynthesis:Nitrogen metabolism:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:Function unknown:pyrD_sub1_fam:agmatinase:hydantase:amidohydrolases:AcOrn-deacetyl:D-hydantoinase:Metabolism:Energy Metabolism:Poorly characterized:Carbohydrate Metabolism:Metabolism:Glutamate family:Amino acid biosynthesis:Degradation of proteins, peptides, and glycopeptides:Protein fate:Metabolism:Global:Metabolism of Cofactors and Vitamins:Metabolism of Other Amino Acids:Amino Acid Metabolism:Nucleotide Metabolism" 482 "Dienelactone hydrolase and related enzymes:Transcriptional regulator:Flp pilus assembly protein TadC:Uncharacterized protein conserved in bacteria:ATP-dependent transcriptional regulator:ABC-type phosphate/phosphonate transport system, periplasmic component:Uncharacterized conserved protein:Uncharacterized protein conserved in bacteria:Predicted membrane protein:Flp pilus assembly protein, secretin CpaC:Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain:Transcription:Cell motility:Inorganic ion transport and metabolism:Secondary metabolites biosynthesis, transport and catabolism:Function unknown:Signal transduction mechanisms:GGDEF:Intracellular trafficking, secretion, and vesicular transport:Information storage and processing:Other:Signal transduction:Poorly characterized:Metabolism:Cellular processes and signaling" 483 "Energy production and conversion:Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase]:Acetyl-CoA acetyltransferase:Anaerobic dehydrogenases, typically selenocysteine-containing:Short-chain dehydrogenases of various substrate specificities:DNA polymerase elongation subunit (family B):ATP-dependent exoDNAse (exonuclease V), alpha subunit - helicase superfamily I member:Transcriptional regulator:Glycine/D-amino acid oxidases (deaminating):Predicted Rossmann fold nucleotide-binding protein involved in DNA uptake:Secreted/periplasmic Zn-dependent peptidases, insulinase-like:ADP-ribose pyrophosphatase:Lhr-like helicases:Beta-lactamase class C and other penicillin binding proteins:Predicted esterase of the alpha-beta hydrolase superfamily:Acyl-CoA dehydrogenases:Nitrate/nitrite transporter:Permeases of the major facilitator superfamily:Aromatic ring hydroxylase:Uncharacterized conserved protein:Predicted enzyme of the cupin superfamily:ABC-type uncharacterized transport system, permease component:TRAP-type uncharacterized transport system, fused permease components:Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain:Amino acid transport and metabolism:Nucleotide transport and metabolism:Coenzyme transport and metabolism:Lipid transport and metabolism:Transcription:Replication, recombination and repair:Posttranslational modification, protein turnover, chaperones:Inorganic ion transport and metabolism:Fatty acid metabolism:Synthesis and degradation of ketone bodies:Valine leucine and isoleucine degradation:Lysine degradation:Tyrosine metabolism:Benzoate degradation:Tryptophan metabolism:beta-Alanine metabolism:Pyruvate metabolism:Glyoxylate and dicarboxylate metabolism:Propanoate metabolism:Butanoate metabolism:Carbon fixation pathways in prokaryotes:Terpenoid backbone biosynthesis:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:ABC transporters:Two-component system:Homologous recombination:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:Function unknown:Signal transduction mechanisms:sensory_box:dprA:recD:AcCoA-C-Actrans:PQQ_syn_pqqF:TRAP_fused:HpaB-2:Intracellular trafficking, secretion, and vesicular transport:Defense mechanisms:Regulatory functions:Other:Fatty acid and phospholipid metabolism:Metabolism:Global:Signal Transduction:Membrane Transport:Environmental Information Processing:Metabolism:Replication and Repair:Genetic Information Processing:Xenobiotics Biodegradation and Metabolism:Metabolism of Terpenoids and Polyketides:Metabolism of Other Amino Acids:Amino Acid Metabolism:Lipid Metabolism:Energy Metabolism:Biosynthesis of cofactors, prosthetic groups, and carriers:Carbohydrate Metabolism:Other:Information storage and processing:Cellular processes and signaling:Metabolism:Poorly characterized:DNA transformation:Cellular processes:Unknown substrate:Transport and binding proteins:DNA replication, recombination, and repair:DNA metabolism:Small molecule interactions" 484 "Ribosomal protein L2:Ribosomal protein L22:Ribosomal protein S3:Ribosomal protein L14:Ribosomal protein L5:Ribosomal protein S11:Ribosomal protein S17:Ribosomal protein L16/L10E:Ribosomal protein L24:DNA-directed RNA polymerase, alpha subunit/40 kD subunit:Ribosomal protein L29:Ribosomal protein S4 and related proteins:Translation, ribosomal structure and biogenesis:Transcription:Purine metabolism:Pyrimidine metabolism:Metabolic pathways:Ribosome:RNA polymerase:L29:rpsC_bact:rpsD_bact:rplV_bact:rplN_bact:rplX_bact:rplP_bact:rplB_bact:rpoA:bact_S11:S17_bact:Ribosomal proteins: synthesis and modification:Protein synthesis:DNA-dependent RNA polymerase:Transcription:Metabolism:Metabolism:Global:Translation:Transcription:Genetic Information Processing:Information storage and processing:Nucleotide Metabolism" 485 "Predicted ATPase of the PP-loop superfamily implicated in cell cycle control:Imidazoleglycerol-phosphate synthase:Glutamine amidotransferase:UDP-N-acetylglucosamine 2-epimerase:Glycosyltransferase:Uncharacterized low-complexity proteins:Membrane protein involved in the export of O-antigen and teichoic acid:Uncharacterized protein conserved in bacteria:Retron-type reverse transcriptase:Cell cycle control, cell division, chromosome partitioning:Amino acid transport and metabolism:Replication, recombination and repair:Cell wall/membrane/envelope biogenesis:Histidine metabolism:Metabolic pathways:Biosynthesis of secondary metabolites:General function prediction only:Function unknown:wecB:IMP_synth_hisH:WbuZ:WbuX:Metabolism:Amino Acid Metabolism:Global:Metabolism:Amino acid biosynthesis:Histidine family:Cell envelope:Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides:Information storage and processing:Cellular processes and signaling:Metabolism:Poorly characterized" 486 "Chromatin structure and dynamics:Deacetylases, including yeast histone deacetylase and acetoin utilization protein:Branched-chain amino acid ABC-type transport system, permease components:Transcriptional regulator:Universal stress protein UspA and related nucleotide-binding proteins:Predicted phosphatase/phosphohexomutase:ABC-type branched-chain amino acid transport systems, periplasmic component:Transcriptional regulator:Type II secretory pathway, component PulD:Outer membrane protein:Multidrug resistance efflux pump:Arabinose efflux permease:Uncharacterized iron-regulated membrane protein:Predicted dienelactone hydrolase:Amino acid transport and metabolism:Carbohydrate transport and metabolism:Transcription:Cell wall/membrane/envelope biogenesis:Cell motility:Phosphonate and phosphinate metabolism:Metabolic pathways:Microbial metabolism in diverse environments:ABC transporters:Bacterial secretion system:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:Function unknown:Signal transduction mechanisms:phosphonatase:outer_NodT:type_II_gspD:urea_ABC_UrtA:urea_trans_UrtB:Intracellular trafficking, secretion, and vesicular transport:Defense mechanisms:Porins:Amino acids, peptides and amines:Transport and binding proteins:Protein and peptide secretion and trafficking:Protein fate:Other:Central intermediary metabolism:Metabolism:Metabolism:Global:Membrane Transport:Environmental Information Processing:Metabolism of Other Amino Acids:Poorly characterized:Metabolism:Cellular processes and signaling:Information storage and processing" 487 "1-acyl-sn-glycerol-3-phosphate acyltransferase:Molecular chaperone, HSP90 family:Serine/threonine protein kinase:ATPases with chaperone activity, ATP-binding subunit:Phosphatidylglycerophosphate synthase:Organic radical activating enzymes:MoxR-like ATPases:Superfamily I DNA and RNA helicases and helicase subunits:ABC-type antimicrobial peptide transport system, ATPase component:Uncharacterized conserved protein:Lysophospholipase:Uncharacterized protein conserved in bacteria:Predicted protein-tyrosine phosphatase:Uncharacterized protein conserved in bacteria:Uncharacterized protein conserved in bacteria:Predicted CDP-diglyceride synthetase/phosphatidate cytidylyltransferase:ABC-type transport system, involved in lipoprotein release, permease component:Lipid transport and metabolism:Transcription:Replication, recombination and repair:Cell wall/membrane/envelope biogenesis:Posttranslational modification, protein turnover, chaperones:Glycerophospholipid metabolism:Metabolic pathways:Bacterial secretion system:General function prediction only:Function unknown:Signal transduction mechanisms:VI_IcmF:VI_minor_4:Defense mechanisms:Environmental Information Processing:Metabolism:Lipid Metabolism:Poorly characterized:Metabolism:Cellular processes and signaling:Information storage and processing:Pathogenesis:Cellular processes:Metabolism:Global:Membrane Transport" 488 "Energy production and conversion:Isopropylmalate/homocitrate/citramalate synthases:Glucose-6-phosphate isomerase:Glutathione synthase/Ribosomal protein S6 modification enzyme (glutaminyl transferase):Aminopeptidase N:ATP-dependent Zn proteases:Transcriptional regulator:Predicted esterase:Carbonic anhydrases/acetyltransferases, isoleucine patch superfamily:Catalase:Zn-dependent alcohol dehydrogenases, class III:Predicted nucleoside-diphosphate sugar epimerases:Acyl dehydratase:Predicted Fe-S protein:Metal-dependent hydrolase:Uncharacterized protein conserved in bacteria:Predicted integral membrane protein:Amino acid transport and metabolism:Carbohydrate transport and metabolism:Coenzyme transport and metabolism:Lipid transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:Cell wall/membrane/envelope biogenesis:Posttranslational modification, protein turnover, chaperones:Inorganic ion transport and metabolism:Glycolysis / Gluconeogenesis:Pentose phosphate pathway:Fatty acid metabolism:Valine leucine and isoleucine biosynthesis:Tyrosine metabolism:Tryptophan metabolism:Glutathione metabolism:Starch and sucrose metabolism:Amino sugar and nucleotide sugar metabolism:Pyruvate metabolism:Chloroalkane and chloroalkene degradation:Naphthalene degradation:Methane metabolism:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:General function prediction only:Function unknown:leuA_yeast:FtsH_fam:glut_syn:pepN_proteo:TIGR02448:CbtA:adh_III_F_hyde:fghA_ester_D:Poorly characterized:Carbohydrate Metabolism:Energy Metabolism:Lipid Metabolism:Amino Acid Metabolism:Metabolism of Other Amino Acids:Xenobiotics Biodegradation and Metabolism:Global:Metabolism:Energy metabolism:Fermentation:Protein fate:Degradation of proteins, peptides, and glycopeptides:Cellular processes:Detoxification:Amino acid biosynthesis:Pyruvate family:Biosynthesis of cofactors, prosthetic groups, and carriers:Glutathione and analogs:Information storage and processing:Cellular processes and signaling:Metabolism:Metabolism" 489 "Energy production and conversion:Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases:Anaerobic dehydrogenases, typically selenocysteine-containing:FAD/FMN-containing dehydrogenases:Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II:Dihydrodipicolinate synthase/N-acetylneuraminate lyase:Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases:Glycerol-3-phosphate dehydrogenase:Sugar (pentulose and hexulose) kinases:Amidases related to nicotinamidase:Predicted transcriptional regulators:Outer membrane protein:TRAP-type C4-dicarboxylate transport system, large permease component:Acyl-CoA dehydrogenases:Uncharacterized protein, possibly involved in aromatic compounds catabolism:Long-chain fatty acid transport protein:AraC-type DNA-binding domain-containing proteins:TRAP-type C4-dicarboxylate transport system, small permease component:Predicted double-glycine peptidase:Predicted metal-dependent hydrolase:Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains:Lipase chaperone:Amino acid transport and metabolism:Nucleotide transport and metabolism:Carbohydrate transport and metabolism:Lipid transport and metabolism:Transcription:Cell wall/membrane/envelope biogenesis:Posttranslational modification, protein turnover, chaperones:Geraniol degradation:Lysine biosynthesis:Glycerophospholipid metabolism:Ether lipid metabolism:Biosynthesis of siderophore group nonribosomal peptides:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:Signal transduction mechanisms:dctM:Intracellular trafficking, secretion, and vesicular transport:Lipid Metabolism:Metabolism:Poorly characterized:Metabolism:Cellular processes and signaling:Information storage and processing:Carbohydrates, organic alcohols, and acids:Transport and binding proteins:Metabolism:Global:Metabolism of Terpenoids and Polyketides:Amino Acid Metabolism" 490 "Energy production and conversion:NhaP-type Na+/H+ and K+/H+ antiporters:Ornithine carbamoyltransferase:Phosphoglycerate dehydrogenase and related dehydrogenases:ATPase components of ABC transporters with duplicated ATPase domains:Predicted dehydrogenase:Transcriptional regulator:Nitroreductase:Biopolymer transport proteins:Biopolymer transport protein:Flavodoxin reductases (ferredoxin-NADPH reductases) family 1:Gamma-aminobutyrate permease and related permeases:Mg-chelatase subunit ChlI:Rubredoxin:Lysophospholipase:Uncharacterized conserved protein:Amino acid transport and metabolism:Coenzyme transport and metabolism:Lipid transport and metabolism:Transcription:Inorganic ion transport and metabolism:Arginine and proline metabolism:Pyruvate metabolism:Vitamin B6 metabolism:Porphyrin and chlorophyll metabolism:Metabolic pathways:Biosynthesis of secondary metabolites:General function prediction only:Function unknown:orni_carb_tr:mal_quin_oxido:Intracellular trafficking, secretion, and vesicular transport:Metabolism:Poorly characterized:Metabolism:Cellular processes and signaling:Information storage and processing:Glutamate family:Amino acid biosynthesis:TCA cycle:Energy metabolism:Metabolism:Global:Metabolism of Cofactors and Vitamins:Amino Acid Metabolism:Carbohydrate Metabolism" 491 "Energy production and conversion:Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases:ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component:ABC-type dipeptide/oligopeptide/nickel transport systems, permease components:Signal transduction histidine kinase:ABC-type dipeptide transport system, periplasmic component:DNA polymerase III, epsilon subunit and related 3'-5' exonucleases:Predicted exporters of the RND superfamily:Predicted acetyltransferases and hydrolases with the alpha/beta hydrolase fold:ABC-type dipeptide/oligopeptide/nickel transport systems, permease components:Alcohol dehydrogenase, class IV:TRAP-type C4-dicarboxylate transport system, large permease component:TRAP-type C4-dicarboxylate transport system, periplasmic component:Beta-lactamase class C and other penicillin binding proteins:Arginine/lysine/ornithine decarboxylases:TRAP-type uncharacterized transport system, periplasmic component:Predicted signal-transduction protein containing cAMP-binding and CBS domains:TRAP-type C4-dicarboxylate transport system, small permease component:Predicted membrane protein:Predicted symporter:Uncharacterized protein related to plant photosystem II stability/assembly factor:Uncharacterized conserved protein:Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain:Amino acid transport and metabolism:Carbohydrate transport and metabolism:Lipid transport and metabolism:Transcription:Replication, recombination and repair:Inorganic ion transport and metabolism:Glycolysis / Gluconeogenesis:Purine metabolism:Pyrimidine metabolism:Arginine and proline metabolism:Glycerolipid metabolism:Pyruvate metabolism:Propanoate metabolism:Methane metabolism:Carbon fixation pathways in prokaryotes:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:ABC transporters:Two-component system:Bacterial chemotaxis:DNA replication:Mismatch repair:Homologous recombination:General function prediction only:Function unknown:Signal transduction mechanisms:sensory_box:dctM:dctP:sss:oligo_HPY:TRAP_TAXI:Ac_CoA_lig_AcsA:Defense mechanisms:Membrane Transport:Environmental Information Processing:Replication and Repair:Genetic Information Processing:Amino Acid Metabolism:Nucleotide Metabolism:Lipid Metabolism:Energy Metabolism:Small molecule interactions:Carbohydrate Metabolism:Transport and binding proteins:Unknown substrate:Amino acids, peptides and amines:Carbohydrates, organic alcohols, and acids:Cations and iron carrying compounds:Information storage and processing:Cellular processes and signaling:Metabolism:Poorly characterized:Regulatory functions:Metabolism:Metabolism:Global:Cell Motility:Cellular Processes:Signal Transduction" 492 "Energy production and conversion:Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit:Glycosyltransferase:Translation elongation factors (GTPases):Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component, and related enzymes:Methyl-accepting chemotaxis protein:Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit:DNA/RNA endonuclease G, NUC1:NADH:flavin oxidoreductases, Old Yellow Enzyme family:FOG: PAS/PAC domain:Predicted deacetylase:Response regulator containing a CheY-like receiver domain and an HD-GYP domain:Nucleotide transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:Cell wall/membrane/envelope biogenesis:Cell motility:Glycolysis / Gluconeogenesis:Citrate cycle (TCA cycle):Valine leucine and isoleucine biosynthesis:Pyruvate metabolism:Butanoate metabolism:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:Two-component system:Bacterial chemotaxis:General function prediction only:Signal transduction mechanisms:sensory_box:small_GTP:PDH_E1_alph_x:Poorly characterized:Carbohydrate Metabolism:Amino Acid Metabolism:Environmental Information Processing:Signal Transduction:Cellular Processes:Cell Motility:Global:Metabolism:Energy metabolism:Pyruvate dehydrogenase:Regulatory functions:Small molecule interactions:Unknown function:General:Information storage and processing:Cellular processes and signaling:Metabolism:Metabolism" 493 "Prolipoprotein diacylglyceryltransferase:Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain:ADP-ribose pyrophosphatase:Transcriptional regulators:Uncharacterized conserved protein:Adenylate cyclase, family 3 (some proteins contain HAMP domain):Uncharacterized protein conserved in bacteria:Precorrin-4 methylase:Flagellar biosynthesis chaperone:Membrane-bound lytic murein transglycosylase B:Paraquat-inducible protein B:Heat shock protein:Uncharacterized protein conserved in bacteria:ABC-type uncharacterized transport system, permease component:Putative Mg2+ and Co2+ transporter CorB:Nucleotide transport and metabolism:Coenzyme transport and metabolism:Transcription:Cell wall/membrane/envelope biogenesis:Cell motility:Posttranslational modification, protein turnover, chaperones:Inorganic ion transport and metabolism:Porphyrin and chlorophyll metabolism:Metabolic pathways:Flagellar assembly:General function prediction only:Function unknown:Signal transduction mechanisms:lgt:cobM_cbiF:MltB_2:fruct_sucro_rep:flagell_FliJ:Intracellular trafficking, secretion, and vesicular transport:Cellular Processes:Biosynthesis of cofactors, prosthetic groups, and carriers:Metabolism of Cofactors and Vitamins:Heme, porphyrin, and cobalamin:Cell envelope:Biosynthesis and degradation of murein sacculus and peptidoglycan:Information storage and processing:Cellular processes and signaling:Metabolism:Poorly characterized:Metabolism:Protein modification and repair:Protein fate:DNA interactions:Regulatory functions:Metabolism:Global:Cell Motility" 494 "Energy production and conversion:Transcriptional regulator:NADPH:quinone reductase and related Zn-dependent oxidoreductases:Cell division protein FtsI/penicillin-binding protein 2:Cation/multidrug efflux pump:Membrane-fusion protein:Outer membrane protein:DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog:AraC-type DNA-binding domain-containing proteins:Prophage antirepressor:Fe2+-dicitrate sensor, membrane component:Transcription:Cell wall/membrane/envelope biogenesis:Inorganic ion transport and metabolism:Peptidoglycan biosynthesis:RNA polymerase:General function prediction only:Signal transduction mechanisms:2A0602:RND_mfp:outer_NodT:sigma70-ECF:Intracellular trafficking, secretion, and vesicular transport:Defense mechanisms:Glycan Biosynthesis and Metabolism:Information storage and processing:Cellular processes and signaling:Metabolism:Poorly characterized:Metabolism:Unknown substrate:Transport and binding proteins:Transcription:Genetic Information Processing:Porins" 495 "ATPases with chaperone activity, ATP-binding subunit:Serine/threonine protein phosphatase:Hemolysin-coregulated protein (uncharacterized):Uncharacterized protein conserved in bacteria:Uncharacterized protein conserved in bacteria:Uncharacterized protein conserved in bacteria:Uncharacterized protein conserved in bacteria:Uncharacterized protein conserved in bacteria:Uncharacterized protein conserved in bacteria:Uncharacterized protein conserved in bacteria:Protein of avirulence locus involved in temperature-dependent protein secretion:Posttranslational modification, protein turnover, chaperones:Bacterial secretion system:General function prediction only:Function unknown:Signal transduction mechanisms:vgr_GE:VI_effect_Hcp1:VI_ClpV1:VI_chp_1:VI_IcmF:VI_chp_2:VI_zyme:VI_chp_5:VI_chp_6:Poorly characterized:Membrane Transport:Cellular processes:Pathogenesis:Cellular processes and signaling:Environmental Information Processing" 496 "Methyl-accepting chemotaxis protein:Methylase of chemotaxis methyl-accepting proteins:Flagellar basal body rod protein:Flagellar basal body protein:Flagellar hook capping protein:Outer membrane protein and related peptidoglycan-associated (lipo)proteins:Flagellar hook-length control protein:Response regulator containing a CheY-like receiver domain and a GGDEF domain:Flagellar basal body rod protein:Predicted glycosyltransferase:Cell wall/membrane/envelope biogenesis:Cell motility:Two-component system:Bacterial chemotaxis:Flagellar assembly:Signal transduction mechanisms:GGDEF:FlgC:FlgB:flgF:Other:Signal Transduction:Cellular Processes:Cell Motility:Cellular processes:Chemotaxis and motility:Signal transduction:Environmental Information Processing:Cellular processes and signaling" 497 "Energy production and conversion:Serine/threonine protein kinase:Signal transduction histidine kinase:Glycine/D-amino acid oxidases (deaminating):ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components:Uncharacterized ABC-type transport system, permease component:ABC-type multidrug transport system, ATPase component:Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs:ABC-type transport system involved in multi-copper enzyme maturation, permease component:Putative threonine efflux protein:Acetyltransferases, including N-acetylases of ribosomal proteins:Arylamine N-acetyltransferase:Adenosine deaminase:Lysophospholipase L1 and related esterases:Nitrous oxidase accessory protein:Predicted membrane protein:ABC-type uncharacterized transport systems, ATPase components:Predicted lipoprotein involved in nitrous oxide reduction:Amino acid transport and metabolism:Nucleotide transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:Replication, recombination and repair:Inorganic ion transport and metabolism:Aminoacyl-tRNA biosynthesis:ABC transporters:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:Function unknown:Signal transduction mechanisms:SsuA_fam:adhes_NPXG:Phn_aa_oxid:para_beta_helix:Defense mechanisms:Translation:Genetic Information Processing:Poorly characterized:Metabolism:Cellular processes and signaling:Information storage and processing:Other:Transport and binding proteins:Membrane Transport:Environmental Information Processing" 498 "Periplasmic component of the Tol biopolymer transport system:Type II secretory pathway, component PulF:Disulfide bond formation protein DsbB:2'-5' RNA ligase:ABC-type polysaccharide/polyol phosphate export systems, permease component:Predicted acyltransferases:Type II secretory pathway, pseudopilin PulG:FOG: EAL domain:AraC-type DNA-binding domain-containing proteins:PEP phosphonomutase and related enzymes:Type II secretory pathway, ATPase PulE/Tfp pilus assembly pathway, ATPase PilB:P pilus assembly protein, pilin FimA:Predicted membrane protein:Carbohydrate transport and metabolism:Lipid transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:Cell wall/membrane/envelope biogenesis:Cell motility:Posttranslational modification, protein turnover, chaperones:ABC transporters:Bacterial secretion system:Function unknown:Signal transduction mechanisms:efflux_EmrB:typeII_sec_gspG:2_5_ligase:IV_pilin_GFxxxE:Intracellular trafficking, secretion, and vesicular transport:Protein and peptide secretion and trafficking:Protein fate:RNA processing:Transcription:Poorly characterized:Membrane Transport:Metabolism:Cellular processes and signaling:Information storage and processing:Environmental Information Processing:Pathogenesis:Cellular processes:Other:Transport and binding proteins" 499 "Energy production and conversion:Uracil phosphoribosyltransferase:Exopolyphosphatase:Predicted enzyme with a TIM-barrel fold:Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases:Signal transduction histidine kinase:2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases:Signal peptidase I:Exonuclease III:Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain:Periplasmic protease:Predicted redox protein, regulator of disulfide bond formation:Protease II:Xanthine/uracil permeases:Uncharacterized protein conserved in bacteria:K+ transporter:Uncharacterized protein conserved in bacteria:ABC-type spermidine/putrescine transport systems, ATPase components:Signal transduction histidine kinase, nitrogen specific:Site-specific recombinase XerD:Predicted secreted protein:Amino acid transport and metabolism:Nucleotide transport and metabolism:Carbohydrate transport and metabolism:Coenzyme transport and metabolism:Transcription:Replication, recombination and repair:Cell wall/membrane/envelope biogenesis:Posttranslational modification, protein turnover, chaperones:Inorganic ion transport and metabolism:Purine metabolism:Pyrimidine metabolism:Metabolic pathways:ABC transporters:Two-component system:Protein export:Base excision repair:General function prediction only:Function unknown:Signal transduction mechanisms:TIGR00044:exoDNase_III:prc:ncs2:upp:Ubi-OHases:CXXU_selWTH:recomb_XerD:sigpep_I_bact:TIGR02449:exo_poly_only:Intracellular trafficking, secretion, and vesicular transport:Enzymes of unknown specificity:Nucleotide Metabolism:Genetic Information Processing:Folding Sorting and Degradation:Replication and Repair:Environmental Information Processing:Membrane Transport:Signal Transduction:Global:Metabolism:Central intermediary metabolism:Phosphorus compounds:Purines, pyrimidines, nucleosides, and nucleotides:Salvage of nucleosides and nucleotides:DNA metabolism:DNA replication, recombination, and repair:Protein fate:Protein and peptide secretion and trafficking:Protein modification and repair:Transport and binding proteins:Nucleosides, purines and pyrimidines:Unknown function:Metabolism:Biosynthesis of cofactors, prosthetic groups, and carriers:Menaquinone and ubiquinone:Information storage and processing:Cellular processes and signaling:Metabolism:Poorly characterized" 500 "Energy production and conversion:Acetyl-CoA acetyltransferase:Dienelactone hydrolase and related enzymes:DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog:Acyl CoA:acetate/3-ketoacid CoA transferase, alpha subunit:Acyl CoA:acetate/3-ketoacid CoA transferase, beta subunit:Chromate transport protein ChrA:AraC-type DNA-binding domain-containing proteins:Na+-transporting NADH:ubiquinone oxidoreductase, subunit NqrF:Protocatechuate 3,4-dioxygenase beta subunit:Fe2+-dicitrate sensor, membrane component:Phenylpropionate dioxygenase and related ring-hydroxylating dioxygenases, large terminal subunit:Muconolactone delta-isomerase:L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily:Small subunit of phenylpropionate dioxygenase:Lipid transport and metabolism:Transcription:Cell wall/membrane/envelope biogenesis:Inorganic ion transport and metabolism:Chlorocyclohexane and chlorobenzene degradation:Benzoate degradation:Fluorobenzoate degradation:Toluene degradation:Aminobenzoate degradation:Styrene degradation:Butanoate metabolism:Nitrogen metabolism:Metabolic pathways:Microbial metabolism in diverse environments:RNA polymerase:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:Signal transduction mechanisms:2A51:AcCoA-C-Actrans:catechol_proteo:mucon_cyclo:sigma70-ECF:muco_delta:anthran_1_2_A:anthran_1_2_B:Metabolism:Global:Metabolism:Transcription:Genetic Information Processing:Xenobiotics Biodegradation and Metabolism:Energy Metabolism:Fatty acid and phospholipid metabolism:Carbohydrate Metabolism:Other:Transport and binding proteins:Anions:Information storage and processing:Cellular processes and signaling:Metabolism:Poorly characterized:Other:Amino acids and amines:Energy metabolism" 501 "RNA processing and modification:Energy production and conversion:Glutamyl- and glutaminyl-tRNA synthetases:Acetyltransferase (isoleucine patch superfamily):RNA 3'-terminal phosphate cyclase:Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain:Predicted Fe-S-cluster redox enzyme:Fe-S oxidoreductase:Predicted GTPases:Micrococcal nuclease (thermonuclease) homologs:Acyl-CoA hydrolase:Uncharacterized conserved protein:Hemolysin activation/secretion protein:Aminoglycoside phosphotransferase:Trans-aconitate methyltransferase:Lipid transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:Replication, recombination and repair:Two-component system:General function prediction only:Function unknown:Signal transduction mechanisms:TIGR00157:RNA_3prim_cycl:queuosine_YadB:SAM_YgiQ:Intracellular trafficking, secretion, and vesicular transport:RNA processing:Transcription:Poorly characterized:Signal Transduction:Metabolism:Environmental Information Processing:Cellular processes and signaling:Information storage and processing:Enzymes of unknown specificity:Unknown function:Translation factors:tRNA and rRNA base modification:Protein synthesis" 502 "Energy production and conversion:Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit:Isopropylmalate/homocitrate/citramalate synthases:Acetyl-CoA acetyltransferase:Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases:Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component, and related enzymes:Enoyl-CoA hydratase/carnithine racemase:Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases):Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit:Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes:Acyl CoA:acetate/3-ketoacid CoA transferase, alpha subunit:Acyl-CoA dehydrogenases:Acyl CoA:acetate/3-ketoacid CoA transferase, beta subunit:Acetyl/propionyl-CoA carboxylase, alpha subunit:Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta):Amino acid transport and metabolism:Lipid transport and metabolism:Glycolysis / Gluconeogenesis:Citrate cycle (TCA cycle):Fatty acid metabolism:Synthesis and degradation of ketone bodies:Glycine serine and threonine metabolism:Valine leucine and isoleucine degradation:Geraniol degradation:Lysine degradation:Benzoate degradation:Tryptophan metabolism:Pyruvate metabolism:Naphthalene degradation:Glyoxylate and dicarboxylate metabolism:Propanoate metabolism:Butanoate metabolism:Methane metabolism:Carbon fixation pathways in prokaryotes:Terpenoid backbone biosynthesis:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:Two-component system:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:lipoamide_DH:AcCoA-C-Actrans:pcaJ_scoB_fam:pcaI_scoA_fam:Environmental Information Processing:Xenobiotics Biodegradation and Metabolism:Metabolism of Terpenoids and Polyketides:Amino Acid Metabolism:Lipid Metabolism:Energy Metabolism:Carbohydrate Metabolism:Fatty acid and phospholipid metabolism:Other:Metabolism:Poorly characterized:Metabolism:Metabolism:Global:Signal Transduction" 503 "Energy production and conversion:Methyl-accepting chemotaxis protein:NADH:flavin oxidoreductases, Old Yellow Enzyme family:3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases:FOG: PAS/PAC domain:Outer membrane protein and related peptidoglycan-associated (lipo)proteins:Response regulator containing a CheY-like receiver domain and an HD-GYP domain:Flp pilus assembly protein, pilin Flp:Uncharacterized protein conserved in bacteria:Lipid transport and metabolism:Transcription:Cell wall/membrane/envelope biogenesis:Cell motility:Valine leucine and isoleucine degradation:Metabolic pathways:Two-component system:Bacterial chemotaxis:Function unknown:Signal transduction mechanisms:sensory_box:HIBADH:Intracellular trafficking, secretion, and vesicular transport:Cellular processes and signaling:Amino Acid Metabolism:Environmental Information Processing:Signal Transduction:Cellular Processes:Cell Motility:Global:Metabolism:Energy metabolism:Amino acids and amines:Regulatory functions:Small molecule interactions:Information storage and processing:Metabolism:Metabolism:Poorly characterized" 504 "Acetyl-CoA acetyltransferase:Outer membrane protein and related peptidoglycan-associated (lipo)proteins:Uncharacterized conserved protein:Uncharacterized conserved protein:Predicted membrane protein:Lipid transport and metabolism:Cell wall/membrane/envelope biogenesis:Fatty acid metabolism:Synthesis and degradation of ketone bodies:Valine leucine and isoleucine degradation:Lysine degradation:Benzoate degradation:Tryptophan metabolism:Pyruvate metabolism:Glyoxylate and dicarboxylate metabolism:Propanoate metabolism:Butanoate metabolism:Carbon fixation pathways in prokaryotes:Terpenoid backbone biosynthesis:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:Two-component system:Function unknown:AcCoA-C-Actrans:TIGR02448:Fatty acid and phospholipid metabolism:Other:Cellular processes and signaling:Metabolism:Poorly characterized:Environmental Information Processing:Xenobiotics Biodegradation and Metabolism:Metabolism of Terpenoids and Polyketides:Amino Acid Metabolism:Lipid Metabolism:Energy Metabolism:Global:Carbohydrate Metabolism:Metabolism:Signal Transduction:Metabolism" 505 "Energy production and conversion:Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase:Dihydroxyacid dehydratase/phosphogluconate dehydratase:Tryptophan synthase beta chain:Tryptophan synthase alpha chain:Anaerobic dehydrogenases, typically selenocysteine-containing:6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase:Glucose-6-phosphate 1-dehydrogenase:Fe-S-cluster-containing hydrogenase components 1:Glycerol kinase:Glycerol-3-phosphate dehydrogenase:Glycerol uptake facilitator and related permeases (Major Intrinsic Protein Family):Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain:2-keto-3-deoxy-6-phosphogluconate aldolase:Glucokinase:NAD-dependent aldehyde dehydrogenases:Transcriptional regulators:Cytochrome c, mono- and diheme variants:Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases:Choline dehydrogenase and related flavoproteins:H+/gluconate symporter and related permeases:Cytochrome c553:Cytochrome b subunit of formate dehydrogenase:Cytochrome c:Gluconate kinase:Amino acid transport and metabolism:Carbohydrate transport and metabolism:Transcription:Glycolysis / Gluconeogenesis:Pentose phosphate pathway:Pentose and glucuronate interconversions:Galactose metabolism:Glycine serine and threonine metabolism:Arginine and proline metabolism:Phenylalanine tyrosine and tryptophan biosynthesis:Glutathione metabolism:Starch and sucrose metabolism:Amino sugar and nucleotide sugar metabolism:Streptomycin biosynthesis:Glycerolipid metabolism:Glycerophospholipid metabolism:Glyoxylate and dicarboxylate metabolism:Methane metabolism:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:Signal transduction mechanisms:trpA:trpB:glk:gntP:MIP:zwf:eda:edd:pgl:glycerol_kin:therm_gnt_kin:GAPDH-I:formate-DH-alph:FDH-beta:formate-DH-gamm:oxido_grp_1:Aromatic amino acid family:Carbohydrate Metabolism:Energy Metabolism:Lipid Metabolism:Amino Acid Metabolism:Metabolism of Other Amino Acids:Biosynthesis of Other Secondary Metabolites:Global:Metabolism:Energy metabolism:Electron transport:Entner-Doudoroff:Glycolysis/gluconeogenesis:Pentose phosphate pathway:Other:Transport and binding proteins:Unknown substrate:Carbohydrates, organic alcohols, and acids:Unknown function:Enzymes of unknown specificity:Amino acid biosynthesis:Metabolism:Information storage and processing:Cellular processes and signaling:Metabolism" 506 "Ribosomal protein S16:Ribosomal protein S18:Ribosomal protein L19:tRNA-(guanine-N1)-methyltransferase:Ribosomal protein L9:Ribosomal protein S6:FKBP-type peptidyl-prolyl cis-trans isomerase (trigger factor):RimM protein, required for 16S rRNA processing:Translation, ribosomal structure and biogenesis:Posttranslational modification, protein turnover, chaperones:Ribosome:S16:trmD:tig:L9:S18:S6:rplS_bact:16S_RimM:tRNA and rRNA base modification:Translation:Transcription:RNA processing:Protein synthesis:Ribosomal proteins: synthesis and modification:Genetic Information Processing:Protein fate:Protein folding and stabilization:Information storage and processing:Cellular processes and signaling" 507 "Energy production and conversion:FAD/FMN-containing dehydrogenases:Predicted membrane protein:ABC-type branched-chain amino acid transport systems, ATPase component:Glutathione S-transferase:Predicted transcriptional regulators:Signal transduction histidine kinase:Sulfate permease and related transporters (MFS superfamily):Acetyl-CoA carboxylase beta subunit:NAD-dependent aldehyde dehydrogenases:ADP-ribose pyrophosphatase:Hydrolases of the alpha/beta superfamily:Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs:Putative threonine efflux protein:Transcriptional regulator:Transcriptional regulators:Mn2+ and Fe2+ transporters of the NRAMP family:Membrane transporters of cations and cationic drugs:Predicted ester cyclase:Predicted periplasmic lipoprotein:Amino acid transport and metabolism:Nucleotide transport and metabolism:Lipid transport and metabolism:Transcription:Posttranslational modification, protein turnover, chaperones:Inorganic ion transport and metabolism:Glutathione metabolism:Glycerolipid metabolism:Glycerophospholipid metabolism:Metabolic pathways:ABC transporters:Two-component system:General function prediction only:Function unknown:Signal transduction mechanisms:TIGR00023:malonate_madL:malonate_madM:nramp:bact_FAD_ox:malonate_beta:urea_trans_UrtE:Poorly characterized:Lipid Metabolism:Metabolism of Other Amino Acids:Environmental Information Processing:Membrane Transport:Signal Transduction:Global:Metabolism:Fatty acid and phospholipid metabolism:Biosynthesis:Transport and binding proteins:Amino acids, peptides and amines:Carbohydrates, organic alcohols, and acids:Cations and iron carrying compounds:Information storage and processing:Cellular processes and signaling:Metabolism:Metabolism" 508 "Type I restriction-modification system methyltransferase subunit:Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis:Glycosyltransferase:Nucleoside-diphosphate-sugar epimerases:UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N-acetylglucosamine-1-phosphate transferase:Type I site-specific restriction-modification system, R (restriction) subunit and related helicases:Restriction endonuclease S subunits:Acyl-[acyl carrier protein]--UDP-N-acetylglucosamine O-acyltransferase:Type II secretory pathway, component PulF:Type II secretory pathway, ATPase PulE/Tfp pilus assembly pathway, ATPase PilB:Tfp pilus assembly protein, major pilin PilA:Carbohydrate transport and metabolism:Cell wall/membrane/envelope biogenesis:Cell motility:Two-component system:IV_pilin_GFxxxE:type_IV_pilB:Intracellular trafficking, secretion, and vesicular transport:Defense mechanisms:Metabolism:Environmental Information Processing:Protein and peptide secretion and trafficking:Protein fate:Signal Transduction:Cellular processes and signaling" 509 "Acetyl-CoA acetyltransferase:Co-chaperonin GroES (HSP10):Dihydrodipicolinate reductase:Molecular chaperone, HSP90 family:Dienelactone hydrolase and related enzymes:Molecular chaperone:Chaperonin GroEL (HSP60 family):ATP-dependent Lon protease, bacterial type:DnaJ-class molecular chaperone with C-terminal Zn finger domain:ATPases with chaperone activity, ATP-binding subunit:Molecular chaperone GrpE (heat shock protein):Cation/multidrug efflux pump:Membrane-fusion protein:ATP-dependent protease HslVU (ClpYQ), ATPase subunit:3-hydroxyacyl-CoA dehydrogenase:Outer membrane protein:Acyl-CoA dehydrogenases:Protein affecting phage T7 exclusion by the F plasmid:Thioredoxin domain-containing protein:Uncharacterized protein conserved in bacteria:ATP-dependent protease HslVU (ClpYQ), peptidase subunit:Amino acid transport and metabolism:Lipid transport and metabolism:Cell wall/membrane/envelope biogenesis:Posttranslational modification, protein turnover, chaperones:Fatty acid metabolism:Valine leucine and isoleucine degradation:Geraniol degradation:Lysine biosynthesis:Lysine degradation:Benzoate degradation:Tryptophan metabolism:beta-Alanine metabolism:alpha-Linolenic acid metabolism:Naphthalene degradation:Propanoate metabolism:Butanoate metabolism:Carbon fixation pathways in prokaryotes:Limonene and pinene degradation:Caprolactam degradation:Biosynthesis of unsaturated fatty acids:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:RNA degradation:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:Function unknown:dapB:hslU:lon:2A0602:thioredoxin:RND_mfp:outer_NodT:AcCoA-C-Actrans:GroEL:DnaJ_bact:prok_dnaK:FadB:chaperone_ClpB:ATP_dep_HslV:Intracellular trafficking, secretion, and vesicular transport:Defense mechanisms:Metabolism of Other Amino Acids:Amino Acid Metabolism:Lipid Metabolism:Energy Metabolism:Carbohydrate Metabolism:Energy metabolism:Electron transport:Fatty acid and phospholipid metabolism:Other:Degradation:Protein fate:Protein folding and stabilization:Degradation of proteins, peptides, and glycopeptides:Transport and binding proteins:Unknown substrate:Porins:Amino acid biosynthesis:Aspartate family:Cellular processes and signaling:Metabolism:Poorly characterized:Metabolism:Global:Folding Sorting and Degradation:Genetic Information Processing:Metabolism:Xenobiotics Biodegradation and Metabolism:Metabolism of Terpenoids and Polyketides" 510 "Predicted GTPase, probable translation factor:ATP phosphoribosyltransferase:Pseudouridine synthase:Peptidyl-tRNA hydrolase:Phosphoribosylpyrophosphate synthetase:Translation initiation factor 2 (IF-2; GTPase):Ribosome-binding factor A:Cell shape-determining protein:Ribosomal protein L25 (general stress protein Ctc):Cell shape-determining protein:Amino acid transport and metabolism:Nucleotide transport and metabolism:Translation, ribosomal structure and biogenesis:Cell wall/membrane/envelope biogenesis:Pentose phosphate pathway:Purine metabolism:Histidine metabolism:Aminoacyl-tRNA biosynthesis:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:Ribosome:hisG:rbfA:TIGR00092:mreC:small_GTP:TruB:pth:ctc_TL5:ribP_PPkin:shape_MreD:General:Carbohydrate Metabolism:Nucleotide Metabolism:Amino Acid Metabolism:Genetic Information Processing:Translation:Global:Metabolism:Purines, pyrimidines, nucleosides, and nucleotides:Purine ribonucleotide biosynthesis:Transcription:RNA processing:Protein synthesis:Other:Ribosomal proteins: synthesis and modification:tRNA and rRNA base modification:Unknown function:Metabolism:Amino acid biosynthesis:Histidine family:Cell envelope:Biosynthesis and degradation of murein sacculus and peptidoglycan:Information storage and processing:Cellular processes and signaling:Metabolism" 511 "Energy production and conversion:Cysteine synthase:3,4-dihydroxy-2-butanone 4-phosphate synthase:Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases:GTP cyclohydrolase I:Gamma-glutamyltransferase:Thiamine biosynthesis protein ThiC:Putative GTPases (G3E family):Transcriptional regulator:Permeases of the drug/metabolite transporter (DMT) superfamily:Membrane proteins related to metalloendopeptidases:Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases):ADP-ribose pyrophosphatase:Sortase and related acyltransferases:Dihydroneopterin aldolase:Uncharacterized conserved protein (some members contain a von Willebrand factor type A (vWA) domain):Uncharacterized conserved protein:Predicted phosphatase homologous to the C-terminal domain of histone macroH2A1:Cation transport ATPase:Uncharacterized conserved protein:Uncharacterized small protein:Uncharacterized protein, possibly involved in nitrogen fixation:Predicted thiol oxidoreductase:Amino acid transport and metabolism:Nucleotide transport and metabolism:Carbohydrate transport and metabolism:Coenzyme transport and metabolism:Lipid transport and metabolism:Transcription:Cell wall/membrane/envelope biogenesis:Inorganic ion transport and metabolism:Cysteine and methionine metabolism:Taurine and hypotaurine metabolism:Selenocompound metabolism:Cyanoamino acid metabolism:Glutathione metabolism:Arachidonic acid metabolism:One carbon pool by folate:Thiamine metabolism:Riboflavin metabolism:Folate biosynthesis:Sulfur metabolism:Metabolic pathways:Microbial metabolism in diverse environments:Protein export:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:Function unknown:folE:g_glut_trans:thiC:ribB:folB_dom:TIGR00702:ccoS:ATPase_P-type:salvage_mtnB:Metabolism:Cellular processes and signaling:Information storage and processing:Thiamine:Glutathione and analogs:Riboflavin, FMN, and FAD:Folic acid:Biosynthesis of cofactors, prosthetic groups, and carriers:Aspartate family:Amino acid biosynthesis:Conserved:Hypothetical proteins:Protein modification and repair:Protein fate:Metabolism:Metabolism:Global:Folding Sorting and Degradation:Genetic Information Processing:Metabolism of Cofactors and Vitamins:Metabolism of Other Amino Acids:Amino Acid Metabolism:Lipid Metabolism:Poorly characterized:Energy Metabolism" 512 "Zonula occludens toxin:General function prediction only:Poorly characterized" 513 "Predicted glutamine amidotransferase:2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway):Zn-dependent hydrolases, including glyoxylases:Bacterial nucleoid DNA-binding protein:Predicted transcriptional regulators:Cell wall-associated hydrolases (invasion-associated proteins):Acetyltransferases, including N-acetylases of ribosomal proteins:Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain:Uncharacterized protein conserved in bacteria:Uncharacterized protein conserved in bacteria:Uncharacterized protein conserved in bacteria:Uncharacterized protein conserved in bacteria:Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain:Isocitrate dehydrogenase kinase/phosphatase:Translation, ribosomal structure and biogenesis:Transcription:Replication, recombination and repair:Cell wall/membrane/envelope biogenesis:Pyruvate metabolism:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:Function unknown:Signal transduction mechanisms:himA:GSH_gloB:Cellular processes:DNA replication, recombination, and repair:DNA metabolism:Carbohydrate Metabolism:Metabolism:Poorly characterized:Metabolism:Cellular processes and signaling:Information storage and processing:Detoxification" 514 "Energy production and conversion:Ornithine carbamoyltransferase:Amino acid transporters:Carbamate kinase:Cytochrome c, mono- and diheme variants:Arginine deiminase:Cbb3-type cytochrome oxidase, cytochrome c subunit:Outer membrane protein W:Cbb3-type cytochrome oxidase, subunit 1:Amino acid transport and metabolism:Cell wall/membrane/envelope biogenesis:Posttranslational modification, protein turnover, chaperones:Oxidative phosphorylation:Purine metabolism:Arginine and proline metabolism:Nitrogen metabolism:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:orni_carb_tr:arcC:ccoN:ccoO:ccoP:2A0302:arcA:Glutamate family:Cellular processes and signaling:Metabolism:Transport and binding proteins:Electron transport:Amino acids and amines:Energy metabolism:Metabolism:Metabolism:Global:Amino Acid Metabolism:Nucleotide Metabolism:Amino acids, peptides and amines:Energy Metabolism:Amino acid biosynthesis" 515 "Energy production and conversion:Polyprenyltransferase (cytochrome oxidase assembly factor):Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases:ABC-type branched-chain amino acid transport systems, periplasmic component:Heme/copper-type cytochrome/quinol oxidases, subunit 1:NAD-dependent aldehyde dehydrogenases:Predicted acetyltransferases and hydrolases with the alpha/beta hydrolase fold:Uncharacterized protein required for cytochrome oxidase assembly:Heme/copper-type cytochrome/quinol oxidases, subunit 2:Heme/copper-type cytochrome/quinol oxidase, subunit 3:3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases:TRAP-type uncharacterized transport system, periplasmic component:Cytochrome oxidase assembly factor:Uncharacterized conserved protein:Uncharacterized conserved protein:Amino acid transport and metabolism:Lipid transport and metabolism:Posttranslational modification, protein turnover, chaperones:Oxidative phosphorylation:Valine leucine and isoleucine degradation:Glycerolipid metabolism:Inositol phosphate metabolism:Propanoate metabolism:Porphyrin and chlorophyll metabolism:Metabolic pathways:Biosynthesis of secondary metabolites:ABC transporters:Two-component system:General function prediction only:Function unknown:cyoE_ctaB:HIBADH:MMSDH:TRAP_TAXI:CoxB:CtaD_CoxA:Poorly characterized:Metabolism:Global:Signal Transduction:Metabolism:Membrane Transport:Environmental Information Processing:Metabolism of Cofactors and Vitamins:Amino Acid Metabolism:Lipid Metabolism:Energy Metabolism:Energy metabolism:Carbohydrate Metabolism:Amino acids and amines:Electron transport:Transport and binding proteins:Unknown substrate:Biosynthesis of cofactors, prosthetic groups, and carriers:Heme, porphyrin, and cobalamin:Cellular processes and signaling:Metabolism" 516 "Predicted amidohydrolase:Mg2+ and Co2+ transporters:Glycine/D-amino acid oxidases (deaminating):Biopolymer transport protein:Membrane protein TerC, possibly involved in tellurium resistance:Purine-cytosine permease and related proteins:Outer membrane receptor proteins, mostly Fe transport:Acetyltransferases, including N-acetylases of ribosomal proteins:Fe2+-dicitrate sensor, membrane component:Conserved secreted protein:Amino acid transport and metabolism:Nucleotide transport and metabolism:Translation, ribosomal structure and biogenesis:Inorganic ion transport and metabolism:General function prediction only:Function unknown:Signal transduction mechanisms:TonB-siderophor:R_switched_Alx:Intracellular trafficking, secretion, and vesicular transport:Metabolism:Cellular processes and signaling:Poorly characterized:Porins:Transport and binding proteins:Information storage and processing" 517 "Energy production and conversion:Xaa-Pro aminopeptidase:Anthranilate/para-aminobenzoate synthases component I:1-acyl-sn-glycerol-3-phosphate acyltransferase:Superfamily II DNA and RNA helicases:Transcriptional regulator:Glycine/D-amino acid oxidases (deaminating):ABC-type transport system involved in resistance to organic solvents, permease component:Alanine racemase:UDP-N-acetylmuramate dehydrogenase:Apolipoprotein N-acyltransferase:Aspartate 1-decarboxylase:Transcriptional regulators of sugar metabolism:Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL homologs:Predicted Rossmann fold nucleotide-binding protein:Predicted signal transduction protein:HrpA-like helicases:Protease II:Xanthine and CO dehydrogenases maturation factor, XdhC/CoxF family:Cytochrome c, mono- and diheme variants:Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS/CutS homologs:Predicted ornithine cyclodeaminase, mu-crystallin homolog:Uncharacterized protein conserved in bacteria:Heat shock protein:Thiol:disulfide interchange protein:Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain:Amino acid transport and metabolism:Carbohydrate transport and metabolism:Coenzyme transport and metabolism:Lipid transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:Replication, recombination and repair:Cell wall/membrane/envelope biogenesis:Posttranslational modification, protein turnover, chaperones:Arginine and proline metabolism:beta-Alanine metabolism:D-Alanine metabolism:Amino sugar and nucleotide sugar metabolism:Peptidoglycan biosynthesis:Pantothenate and CoA biosynthesis:Folate biosynthesis:Metabolic pathways:Biosynthesis of secondary metabolites:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:Function unknown:Signal transduction mechanisms:TIGR00056:murB:panD:sensory_box:alr:lnt:pabB:TIGR00730:DEAH_box_HrpA:Metabolism:Carbohydrate Metabolism:Amino Acid Metabolism:Metabolism of Other Amino Acids:Glycan Biosynthesis and Metabolism:Metabolism of Cofactors and Vitamins:Global:Metabolism:Regulatory functions:Small molecule interactions:Protein fate:Protein modification and repair:Hypothetical proteins:Conserved:Unknown function:Enzymes of unknown specificity:Biosynthesis of cofactors, prosthetic groups, and carriers:Folic acid:Pantothenate and coenzyme A:Cell envelope:Biosynthesis and degradation of murein sacculus and peptidoglycan:Information storage and processing:Cellular processes and signaling:Metabolism:Poorly characterized" 518 "Flagellar biosynthesis/type III secretory pathway protein:Type II secretory pathway, component PulD:AraC-type DNA-binding domain-containing proteins:Type III secretory pathway, lipoprotein EscJ:NAD+--asparagine ADP-ribosyltransferase:Transcription:Cell motility:Bacterial secretion system:Signal transduction mechanisms:III_needle:yscI_hrpB_dom:HrpE_YscL_not:type_III_yscD:type_III_yscE:type_III_yscG:type_III_yopR:type_III_yscB:type_III_yscC:III_secr_YscJ:YscW:Intracellular trafficking, secretion, and vesicular transport:Information storage and processing:Cellular processes and signaling:Cellular processes:Environmental Information Processing:Membrane Transport:Pathogenesis" 519 "Energy production and conversion:Membrane protease subunits, stomatin/prohibitin homologs:Protein-tyrosine-phosphatase:Predicted flavoprotein:Transcriptional regulator:Glycerophosphoryl diester phosphodiesterase:Predicted transcriptional regulators:Na+/H+ antiporter NhaD and related arsenite permeases:Zn-dependent alcohol dehydrogenases:Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain:Predicted membrane protein:Predicted ATPase:Multidrug resistance efflux pump:ABC-type sugar transport system, periplasmic component:Pirin-related protein:ABC-type Fe3+ transport system, periplasmic component:Acyl-CoA dehydrogenases:Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases:AraC-type DNA-binding domain-containing proteins:Uncharacterized protein conserved in bacteria:Uncharacterized enzyme involved in biosynthesis of extracellular polysaccharides:Arylsulfatase A and related enzymes:Uncharacterized iron-regulated membrane protein:Carbohydrate transport and metabolism:Lipid transport and metabolism:Transcription:Posttranslational modification, protein turnover, chaperones:Inorganic ion transport and metabolism:Glycerophospholipid metabolism:ABC transporters:General function prediction only:Function unknown:Signal transduction mechanisms:2a45:resist_ArsH:alk_sulf_monoox:Defense mechanisms:Environmental Information Processing:Metabolism:Lipid Metabolism:Poorly characterized:Metabolism:Cellular processes and signaling:Information storage and processing:Detoxification:Cellular processes:Other:Transport and binding proteins:Sulfur metabolism:Central intermediary metabolism:Membrane Transport" 520 "Dimethyladenosine transferase (rRNA methylation):Folate-dependent phosphoribosylglycinamide formyltransferase PurN:Spermidine synthase:Pseudouridylate synthases, 23S RNA-specific:S-adenosylmethionine:tRNA-ribosyltransferase-isomerase (queuine synthetase):Rad3-related DNA helicases:Phosphatidylglycerophosphatase A and related proteins:Disulfide bond chaperones of the HSP33 family:Transcriptional regulators of sugar metabolism:Predicted ATPase:Sulfur transfer protein involved in thiamine biosynthesis:Transcriptional accessory protein:16S RNA G1207 methylase RsmC:DNA recombination-dependent growth factor C:Outer membrane cobalamin receptor protein:Amino acid transport and metabolism:Nucleotide transport and metabolism:Carbohydrate transport and metabolism:Coenzyme transport and metabolism:Lipid transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:Replication, recombination and repair:Posttranslational modification, protein turnover, chaperones:Purine metabolism:Cysteine and methionine metabolism:Arginine and proline metabolism:beta-Alanine metabolism:Glutathione metabolism:Glycerophospholipid metabolism:One carbon pool by folate:Aminoacyl-tRNA biosynthesis:Metabolic pathways:Biosynthesis of secondary metabolites:Sulfur relay system:General function prediction only:queA:speE:PurN:ksgA:thiS:TonB-B12:Poorly characterized:Lipid Metabolism:Nucleotide Metabolism:Amino Acid Metabolism:Metabolism of Other Amino Acids:Metabolism of Cofactors and Vitamins:Genetic Information Processing:Translation:Folding Sorting and Degradation:Global:Metabolism:Central intermediary metabolism:Polyamine biosynthesis:Purines, pyrimidines, nucleosides, and nucleotides:Purine ribonucleotide biosynthesis:Protein synthesis:tRNA and rRNA base modification:Transport and binding proteins:Porins:Biosynthesis of cofactors, prosthetic groups, and carriers:Thiamine:Information storage and processing:Cellular processes and signaling:Metabolism:Metabolism" 521 "NhaP-type Na+/H+ and K+/H+ antiporters:Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase]:Predicted integral membrane protein:Dienelactone hydrolase and related enzymes:FOG: CBS domain:Exonuclease III:Catalase:Uncharacterized conserved protein:Phosphatidylserine/phosphatidylglycerophosphate/cardiolipin synthases and related enzymes:Predicted membrane protein:Predicted membrane protein:Mn-containing catalase:Uncharacterized protein conserved in bacteria:Predicted small integral membrane protein:Amino acid transport and metabolism:Coenzyme transport and metabolism:Lipid transport and metabolism:Replication, recombination and repair:Inorganic ion transport and metabolism:Tryptophan metabolism:Glycerophospholipid metabolism:Pyruvate metabolism:Methane metabolism:Metabolic pathways:Microbial metabolism in diverse environments:Base excision repair:Non-homologous end-joining:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:Function unknown:exoDNase_III:Ku_bact:Poorly characterized:Metabolism:Information storage and processing:DNA replication, recombination, and repair:DNA metabolism:Metabolism:Metabolism:Global:Replication and Repair:Genetic Information Processing:Amino Acid Metabolism:Lipid Metabolism:Energy Metabolism:Carbohydrate Metabolism" 522 "Glycosyltransferase:Glycosyltransferases involved in cell wall biogenesis:Uncharacterized membrane protein, putative virulence factor:Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains):Mannose-1-phosphate guanylyltransferase:DnaJ-domain-containing proteins 1:Chromosome segregation ATPases:Flagellar motor component:Flagellar motor protein:Periplasmic protein involved in polysaccharide export:Transcriptional regulators:Sugar transferases involved in lipopolysaccharide synthesis:Uncharacterized homolog of the cytoplasmic domain of flagellar protein FhlB:Uncharacterized protein involved in exopolysaccharide biosynthesis:Fucose 4-O-acetylase and related acetyltransferases:Beta-xylosidase:Cell cycle control, cell division, chromosome partitioning:Carbohydrate transport and metabolism:Transcription:Cell wall/membrane/envelope biogenesis:Cell motility:Posttranslational modification, protein turnover, chaperones:Fructose and mannose metabolism:Starch and sucrose metabolism:Amino sugar and nucleotide sugar metabolism:Metabolic pathways:Biosynthesis of secondary metabolites:Two-component system:Bacterial chemotaxis:Flagellar assembly:General function prediction only:Function unknown:GMP_PMI:SMC_prok_B:WcaJ_sugtrans:Metabolism:Carbohydrate Metabolism:Environmental Information Processing:Signal Transduction:Cellular Processes:Cell Motility:Global:Metabolism:DNA metabolism:Chromosome-associated proteins:Cell envelope:Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides:Information storage and processing:Cellular processes and signaling:Metabolism:Poorly characterized" 523 "Energy production and conversion:Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase]:Predicted Zn-dependent proteases and their inactivated homologs:Predicted flavoprotein:Aspartate/tyrosine/aromatic aminotransferase:Acetyltransferases:ATPases of the AAA+ class:Transcriptional regulator:Glutathione S-transferase:Nucleoside phosphorylase:Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases):Phosphoenolpyruvate-protein kinase (PTS system EI component in bacteria):Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog):Chromosome segregation ATPases:Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific:Uncharacterized conserved protein:Transcriptional regulators:Predicted Rossmann fold nucleotide-binding protein:Pirin-related protein:Predicted acyl-CoA transferases/carnitine dehydratase:N-acetylglucosamine-6-phosphate deacetylase:NADH:flavin oxidoreductases, Old Yellow Enzyme family:Acyl-CoA dehydrogenases:N-terminal domain of molybdenum-binding protein:Uncharacterized protein, possibly involved in aromatic compounds catabolism:Putative NADP-dependent oxidoreductases:Transcriptional regulators:Predicted phosphosugar isomerases:Uncharacterized conserved protein:Rhodanese-related sulfurtransferase:Predicted periplasmic ligand-binding sensor domain:Uncharacterized protein conserved in bacteria:Cell cycle control, cell division, chromosome partitioning:Amino acid transport and metabolism:Nucleotide transport and metabolism:Carbohydrate transport and metabolism:Coenzyme transport and metabolism:Lipid transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:Cell wall/membrane/envelope biogenesis:Posttranslational modification, protein turnover, chaperones:Inorganic ion transport and metabolism:Fatty acid metabolism:Purine metabolism:Cysteine and methionine metabolism:Valine leucine and isoleucine biosynthesis:Lysine degradation:Arginine and proline metabolism:Benzoate degradation:Tryptophan metabolism:Glutathione metabolism:Amino sugar and nucleotide sugar metabolism:Butanoate metabolism:C5-Branched dibasic acid metabolism:Pantothenate and CoA biosynthesis:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:Phosphotransferase system (PTS):Sulfur relay system:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:Function unknown:Signal transduction mechanisms:nagA:sensory_box:unchar_dom_1:ModE_repress:EIIB_glc:PTBA:AMP-nucleosdse:Cellular processes and signaling:Information storage and processing:PTS:Signal transduction:Small molecule interactions:Other:Regulatory functions:Amino sugars:Central intermediary metabolism:Metabolism:Metabolism:Global:Membrane Transport:Environmental Information Processing:Folding Sorting and Degradation:Genetic Information Processing:Xenobiotics Biodegradation and Metabolism:Metabolism of Cofactors and Vitamins:Metabolism of Other Amino Acids:Amino Acid Metabolism:Nucleotide Metabolism:Lipid Metabolism:Poorly characterized:Carbohydrate Metabolism:Metabolism" 524 "Energy production and conversion:4-aminobutyrate aminotransferase and related aminotransferases:Adenosylmethionine-8-amino-7-oxononanoate aminotransferase:Glutamine synthetase:Zn-dependent protease with chaperone function:GMP synthase - Glutamine amidotransferase domain:cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases:Glycine/D-amino acid oxidases (deaminating):Integral membrane protein, interacts with FtsH:Predicted transcriptional regulators:NAD-dependent aldehyde dehydrogenases:Transcriptional regulator:Predicted transcriptional regulators:Predicted glutamine amidotransferases:Choline dehydrogenase and related flavoproteins:D-serine dehydratase:Amino acid transport and metabolism:Nucleotide transport and metabolism:Coenzyme transport and metabolism:Transcription:Posttranslational modification, protein turnover, chaperones:Alanine aspartate and glutamate metabolism:Glycine serine and threonine metabolism:Valine leucine and isoleucine degradation:Lysine degradation:Arginine and proline metabolism:beta-Alanine metabolism:Propanoate metabolism:Nitrogen metabolism:Metabolic pathways:Microbial metabolism in diverse environments:Two-component system:General function prediction only:Signal transduction mechanisms:GABAtrnsam:SSADH:BADH:betA:D_Ser_am_lyase:betaine_BetI:Poorly characterized:Carbohydrate Metabolism:Energy Metabolism:Amino Acid Metabolism:Metabolism of Other Amino Acids:Environmental Information Processing:Signal Transduction:Global:Metabolism:Central intermediary metabolism:Other:Energy metabolism:Amino acids and amines:Regulatory functions:DNA interactions:Cellular processes:Adaptations to atypical conditions:Information storage and processing:Cellular processes and signaling:Metabolism:Metabolism" 525 "Nitrogen regulatory protein PII:ATPases with chaperone activity, ATP-binding subunit:Cold shock proteins:Ribosome-associated protein Y (PSrp-1):Carbon storage regulator (could also regulate swarming and quorum sensing):Large-conductance mechanosensitive channel:Uncharacterized conserved protein:Predicted periplasmic/secreted protein:Amino acid transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:Cell wall/membrane/envelope biogenesis:Posttranslational modification, protein turnover, chaperones:Aminoacyl-tRNA biosynthesis:Two-component system:Function unknown:Signal transduction mechanisms:csrA:mscL:yfiA:cspD:ClpA:Information storage and processing:Translation:Environmental Information Processing:Signal Transduction:Regulatory functions:RNA interactions:Protein synthesis:Translation factors:Protein fate:Degradation of proteins, peptides, and glycopeptides:Cellular processes:Adaptations to atypical conditions:Genetic Information Processing:Cellular processes and signaling:Metabolism:Poorly characterized" 526 "Energy production and conversion:Lactoylglutathione lyase and related lyases:Biotin carboxylase:Transcriptional regulator:Uncharacterized proteins, homologs of lactam utilization protein B:TRAP-type C4-dicarboxylate transport system, large permease component:TRAP-type C4-dicarboxylate transport system, periplasmic component:Predicted acyl-CoA transferases/carnitine dehydratase:Acyl-CoA dehydrogenases:Allophanate hydrolase subunit 2:Allophanate hydrolase subunit 1:Uncharacterized protein involved in propionate catabolism:Citrate lyase beta subunit:Uncharacterized conserved protein:Amino acid transport and metabolism:Carbohydrate transport and metabolism:Lipid transport and metabolism:Transcription:Citrate cycle (TCA cycle):Fatty acid biosynthesis:Fatty acid metabolism:Valine leucine and isoleucine degradation:beta-Alanine metabolism:Pyruvate metabolism:Propanoate metabolism:Carbon fixation pathways in prokaryotes:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:Two-component system:General function prediction only:Function unknown:urea_amlyse_rel:dctM:dctP:Metabolism:Metabolism:Global:Signal Transduction:Environmental Information Processing:Metabolism of Other Amino Acids:Amino Acid Metabolism:Lipid Metabolism:Energy Metabolism:General:Carbohydrate Metabolism:Information storage and processing:Metabolism:Poorly characterized:Unknown function:Carbohydrates, organic alcohols, and acids:Transport and binding proteins" 527 "Energy production and conversion:Short-chain dehydrogenases of various substrate specificities:3-oxoacyl-[acyl-carrier-protein] synthase III:2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases:Non-ribosomal peptide synthetase modules and related proteins:Cytochrome P450:Arabinose efflux permease:Ketosteroid isomerase-related protein:Carbohydrate transport and metabolism:Coenzyme transport and metabolism:Lipid transport and metabolism:Fatty acid biosynthesis:Bisphenol degradation:Polycyclic aromatic hydrocarbon degradation:Aminobenzoate degradation:Limonene and pinene degradation:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:fabH:AA-adenyl-dom:Fatty acid and phospholipid metabolism:Lipid Metabolism:Metabolism of Terpenoids and Polyketides:Xenobiotics Biodegradation and Metabolism:Global:Metabolism:Metabolism:Biosynthesis:Metabolism:Poorly characterized" 528 "Energy production and conversion:Predicted ATPase of the PP-loop superfamily implicated in cell cycle control:Predicted rRNA methylase (SpoU class):Histidinol phosphatase and related phosphatases:3-dehydroquinate synthetase:Predicted GTPase:Transcriptional regulator:Signal transduction histidine kinase:Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain:Enzyme related to GTP cyclohydrolase I:Apolipoprotein N-acyltransferase:Membrane-fusion protein:Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1:16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases:Uncharacterized conserved protein:Exonuclease VII, large subunit:Transcriptional regulators:AraC-type DNA-binding domain-containing proteins:Uncharacterized protein conserved in bacteria:Predicted Fe-S protein:Cytochrome c556:Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain:Cell cycle control, cell division, chromosome partitioning:Amino acid transport and metabolism:Coenzyme transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:Replication, recombination and repair:Cell wall/membrane/envelope biogenesis:Phenylalanine tyrosine and tryptophan biosynthesis:Lipopolysaccharide biosynthesis:Metabolic pathways:Biosynthesis of secondary metabolites:Two-component system:Mismatch repair:General function prediction only:Function unknown:Signal transduction mechanisms:TIGR00093:rRNA_methyl_2:sensory_box:small_GTP:xseA:lnt:TIGR00726:aroB:Histidinol-ppas:RND_mfp:lysidine_TilS_N:QueF:Unknown function:Amino Acid Metabolism:Glycan Biosynthesis and Metabolism:Genetic Information Processing:Replication and Repair:Environmental Information Processing:Signal Transduction:Global:Metabolism:Regulatory functions:Small molecule interactions:DNA metabolism:Degradation of DNA:Transcription:RNA processing:Protein synthesis:tRNA and rRNA base modification:Protein fate:Protein modification and repair:Transport and binding proteins:Unknown substrate:Metabolism:General:Amino acid biosynthesis:Aromatic amino acid family:Information storage and processing:Cellular processes and signaling:Metabolism:Poorly characterized" 529 "Energy production and conversion:Uroporphyrinogen-III methylase:Collagenase and related proteases:Transcriptional regulators:Cytochrome c, mono- and diheme variants:Putative lipid carrier protein:Cytochrome c551/c552:Coenzyme transport and metabolism:Lipid transport and metabolism:Transcription:Posttranslational modification, protein turnover, chaperones:Porphyrin and chlorophyll metabolism:Metabolic pathways:Biosynthesis of secondary metabolites:cobA_cysG_Cterm:Metabolism:Metabolism of Cofactors and Vitamins:Global:Metabolism:Biosynthesis of cofactors, prosthetic groups, and carriers:Heme, porphyrin, and cobalamin:Information storage and processing:Cellular processes and signaling:Metabolism" 530 "ATPases involved in chromosome partitioning:Chemotaxis protein histidine kinase and related kinases:Chemotaxis signal transduction protein:DNA-directed RNA polymerase specialized sigma subunit:Flagellar basal body P-ring biosynthesis protein:Flagellar biosynthesis pathway, component FlhA:Flagellar GTP-binding protein:Flagellar motor switch protein:Flagellar hook-basal body protein:Flagellar biosynthesis/type III secretory pathway lipoprotein:Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains:Negative regulator of flagellin synthesis (anti-sigma28 factor):Flagellar biosynthesis/type III secretory pathway chaperone:Signal transduction histidine kinase:Cell cycle control, cell division, chromosome partitioning:Transcription:Cell motility:Posttranslational modification, protein turnover, chaperones:Two-component system:Bacterial chemotaxis:Flagellar assembly:RNA polymerase:Signal transduction mechanisms:fliE:fliF:fliG:FlhA:FliA_WhiG:flgA_cterm:FlhF:FlgM_jcvi:Intracellular trafficking, secretion, and vesicular transport:Environmental Information Processing:Cellular processes and signaling:Transcription:Information storage and processing:Chemotaxis and motility:Cellular processes:Genetic Information Processing:Cell Motility:Cellular Processes:Signal Transduction" 531 "Energy production and conversion:NADH:ubiquinone oxidoreductase 49 kD subunit 7:NADH:ubiquinone oxidoreductase subunit 11 or 4L (chain K):NADH:ubiquinone oxidoreductase subunit 6 (chain J):NADH:ubiquinone oxidoreductase subunit 1 (chain H):NADH:ubiquinone oxidoreductase subunit 2 (chain N):NADH:ubiquinone oxidoreductase subunit 4 (chain M):NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit:NADH dehydrogenase/NADH:ubiquinone oxidoreductase 75 kD subunit (chain G):Formate hydrogenlyase subunit 6/NADH:ubiquinone oxidoreductase 23 kD subunit (chain I):NADH:ubiquinone oxidoreductase, NADH-binding (51 kD) subunit:NADH:ubiquinone oxidoreductase 24 kD subunit:Inorganic ion transport and metabolism:Oxidative phosphorylation:Metabolic pathways:NDH_I_N:nuoE_fam:nuoF_fam:NuoC_fam:NuoI:NDH_I_M:NuoG:NDH_I_L:Electron transport:Energy Metabolism:Global:Metabolism:Energy metabolism:Metabolism:Metabolism" 532 "Energy production and conversion:Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase]:Lactoylglutathione lyase and related lyases:Pyruvate kinase:Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily):Gamma-aminobutyrate permease and related permeases:ABC-type spermidine/putrescine transport system, permease component I:NAD(P)H-nitrite reductase:Uncharacterized conserved protein:Cytosine/uracil/thiamine/allantoin permeases:Acyl-CoA dehydrogenases:FOG: EAL domain:Cytochrome c5:ABC-type spermidine/putrescine transport systems, ATPase components:Amino acid transport and metabolism:Nucleotide transport and metabolism:Carbohydrate transport and metabolism:Coenzyme transport and metabolism:Lipid transport and metabolism:Glycolysis / Gluconeogenesis:Fatty acid metabolism:Purine metabolism:Valine leucine and isoleucine degradation:beta-Alanine metabolism:Pyruvate metabolism:Aminobenzoate degradation:Propanoate metabolism:Nitrogen metabolism:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:General function prediction only:Function unknown:Signal transduction mechanisms:GGDEF:pyruv_kin:potA:adhes_NPXG:nitri_red_nirB:Poorly characterized:Carbohydrate Metabolism:Energy Metabolism:Lipid Metabolism:Nucleotide Metabolism:Amino Acid Metabolism:Metabolism of Other Amino Acids:Xenobiotics Biodegradation and Metabolism:Global:Metabolism:Central intermediary metabolism:Nitrogen metabolism:Energy metabolism:Glycolysis/gluconeogenesis:Transport and binding proteins:Amino acids, peptides and amines:Signal transduction:Other:Cellular processes and signaling:Metabolism:Metabolism" 533 "1,4-alpha-glucan branching enzyme:Glycogen synthase:Glycosidases:FOG: CBS domain:Threonine dehydrogenase and related Zn-dependent dehydrogenases:Type II secretory pathway, pullulanase PulA and related glycosidases:4-alpha-glucanotransferase:Uncharacterized conserved protein:Maltooligosyl trehalose synthase:Predicted outer membrane protein:Amino acid transport and metabolism:Carbohydrate transport and metabolism:Starch and sucrose metabolism:Metabolic pathways:General function prediction only:Function unknown:malQ:branching_enzym:glgA:glgX_debranch:TIGR02284:trehalose_TreY:trehalose_TreZ:treS_nterm:Metabolism:Carbohydrate Metabolism:Global:Metabolism:Energy metabolism:Biosynthesis and degradation of polysaccharides:Metabolism:Poorly characterized" 534 "Short-chain dehydrogenases of various substrate specificities:Esterase/lipase:Amino acid permeases:Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases):Threonine dehydrogenase and related Zn-dependent dehydrogenases:3-hydroxyacyl-CoA dehydrogenase:Predicted flavoprotein involved in K+ transport:Adenosine deaminase:Sugar phosphate permease:Predicted acetyltransferase:Ethanolamine utilization protein:Uncharacterized protein conserved in bacteria:Site-specific recombinase XerC:Predicted permease, DMT superfamily:Amino acid transport and metabolism:Nucleotide transport and metabolism:Carbohydrate transport and metabolism:Lipid transport and metabolism:Replication, recombination and repair:Inorganic ion transport and metabolism:Benzoate degradation:Butanoate metabolism:Metabolic pathways:Microbial metabolism in diverse environments:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:Function unknown:lucif_BA3436:Carbohydrate Metabolism:Metabolism:Poorly characterized:Metabolism:Information storage and processing:Enzymes of unknown specificity:Unknown function:Metabolism:Global:Xenobiotics Biodegradation and Metabolism" 535 "Energy production and conversion:Fumarase:Predicted divalent heavy-metal cations transporter:Superoxide dismutase:DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog:AraC-type DNA-binding domain-containing proteins:Precorrin-6B methylase 2:Siderophore-interacting protein:Heme oxygenase:Coenzyme transport and metabolism:Transcription:Inorganic ion transport and metabolism:Citrate cycle (TCA cycle):Carbon fixation pathways in prokaryotes:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:RNA polymerase:sigma70-ECF:Information storage and processing:Carbohydrate Metabolism:Energy Metabolism:Genetic Information Processing:Transcription:Global:Metabolism:Metabolism:Metabolism" 536 "Energy production and conversion:GMP synthase - Glutamine amidotransferase domain:Transcriptional regulator:2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases:Enoyl-CoA hydratase/carnithine racemase:Phosphoenolpyruvate-protein kinase (PTS system EI component in bacteria):Fructose-1-phosphate kinase and related fructose-6-phosphate kinase (PfkB):ABC-type proline/glycine betaine transport systems, periplasmic components:Uncharacterized protein conserved in bacteria:Predicted membrane protein:Protocatechuate 3,4-dioxygenase beta subunit:P pilus assembly protein, pilin FimA:Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain:Ornithine/acetylornithine aminotransferase:Predicted permease, DMT superfamily:Amino acid transport and metabolism:Nucleotide transport and metabolism:Carbohydrate transport and metabolism:Coenzyme transport and metabolism:Lipid transport and metabolism:Transcription:Cell motility:Fructose and mannose metabolism:Fatty acid metabolism:Valine leucine and isoleucine degradation:Geraniol degradation:Lysine biosynthesis:Lysine degradation:Arginine and proline metabolism:Benzoate degradation:Tryptophan metabolism:beta-Alanine metabolism:Polycyclic aromatic hydrocarbon degradation:Aminobenzoate degradation:Propanoate metabolism:Butanoate metabolism:Limonene and pinene degradation:Caprolactam degradation:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:ABC transporters:Phosphotransferase system (PTS):Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:Function unknown:TIGR00698:PTS_HPr_family:pbenz_hydroxyl:protocat_beta:protocat_alph:TF_pcaQ:1-PFK:ABC_choline_bnd:Intracellular trafficking, secretion, and vesicular transport:Metabolism:Cellular processes and signaling:Information storage and processing:PTS:Metabolism:Global:Signal transduction:Conserved:Hypothetical proteins:Amino acids, peptides and amines:Transport and binding proteins:Membrane Transport:Environmental Information Processing:DNA interactions:Metabolism:Xenobiotics Biodegradation and Metabolism:Regulatory functions:Metabolism of Terpenoids and Polyketides:Metabolism of Other Amino Acids:Amino Acid Metabolism:Lipid Metabolism:Other:Energy metabolism:Poorly characterized:Carbohydrate Metabolism" 537 "Energy production and conversion:Transcriptional regulator:Hydrolases of the alpha/beta superfamily:ABC-type multidrug transport system, ATPase and permease components:Acyl carrier protein phosphodiesterase:Predicted membrane protein:Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM/CutM homologs:Flagellar biosynthesis pathway, component FlhB:Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL homologs:Transcriptional regulators:Allophanate hydrolase subunit 1:Membrane transporters of cations and cationic drugs:FOG: GGDEF domain:AraC-type DNA-binding domain-containing proteins:Sugar phosphate permease:DNA-binding HTH domain-containing proteins:PAP2 (acid phosphatase) superfamily protein:Predicted ATPase:Predicted alpha/beta hydrolase:Amino acid transport and metabolism:Carbohydrate transport and metabolism:Lipid transport and metabolism:Transcription:Cell motility:Inorganic ion transport and metabolism:Purine metabolism:Aminoacyl-tRNA biosynthesis:Metabolic pathways:Microbial metabolism in diverse environments:Flagellar assembly:General function prediction only:Function unknown:Signal transduction mechanisms:sensory_box:GGDEF:flhB:TIGR00370:MsbA_rel:Intracellular trafficking, secretion, and vesicular transport:Defense mechanisms:Translation:Genetic Information Processing:Conserved:Nucleotide Metabolism:Signal transduction:Other:Information storage and processing:Cellular processes and signaling:Metabolism:Poorly characterized:Metabolism:Hypothetical proteins:Chemotaxis and motility:Cellular processes:Small molecule interactions:Regulatory functions:Metabolism:Global:Cell Motility:Cellular Processes" 538 "Energy production and conversion:Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase]:Asparagine synthase (glutamine-hydrolyzing):Transcriptional regulator:Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily):Signal transduction histidine kinase:ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components:Fucose permease:Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain:Cation/multidrug efflux pump:Membrane-fusion protein:NAD-dependent aldehyde dehydrogenases:DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog:Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases:Sugar phosphate permease:Arabinose efflux permease:Predicted membrane protein:Fatty acid desaturase:Predicted periplasmic protein:Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain:Small subunit of phenylpropionate dioxygenase:Amino acid transport and metabolism:Carbohydrate transport and metabolism:Coenzyme transport and metabolism:Lipid transport and metabolism:Transcription:Cell wall/membrane/envelope biogenesis:Inorganic ion transport and metabolism:Glycolysis / Gluconeogenesis:Pentose and glucuronate interconversions:Ascorbate and aldarate metabolism:Fatty acid metabolism:Alanine aspartate and glutamate metabolism:Valine leucine and isoleucine degradation:Lysine degradation:Arginine and proline metabolism:Histidine metabolism:Chlorocyclohexane and chlorobenzene degradation:Tryptophan metabolism:beta-Alanine metabolism:Glycerolipid metabolism:Pyruvate metabolism:Chloroalkane and chloroalkene degradation:Aminobenzoate degradation:Propanoate metabolism:Limonene and pinene degradation:Nitrogen metabolism:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:ABC transporters:Two-component system:RNA polymerase:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:Function unknown:Signal transduction mechanisms:GGDEF:cztS_silS_copS:cztR_silR_copR:asn_synth_AEB:SsuA_fam:RND_mfp:sigma70-ECF:Defense mechanisms:Xenobiotics Biodegradation and Metabolism:Metabolism:Metabolism of Terpenoids and Polyketides:Metabolism of Other Amino Acids:Amino Acid Metabolism:Lipid Metabolism:Energy Metabolism:Carbohydrate Metabolism:Transport and binding proteins:Unknown substrate:Other:Amino acid biosynthesis:Aspartate family:Signal transduction:Other:Information storage and processing:Cellular processes and signaling:Metabolism:Poorly characterized:Metabolism:Global:Signal Transduction:Membrane Transport:Environmental Information Processing:Transcription:Genetic Information Processing" 539 "Ribosomal protein S12:Ribosomal protein S7:GTPases - translation elongation factors:Ribosomal protein S10:Ribosomal protein S2:Ribosomal protein L11:Ribosomal protein L1:Ribosomal protein L3:Ribosomal protein L7/L12:Ribosomal protein L10:Translation elongation factor Ts:Translation elongation factors (GTPases):Translation, ribosomal structure and biogenesis:Ribosome:tsf:small_GTP:L12:rpsL_bact:rpsB_bact:rpsG_bact:rpsJ_bact:rplA_bact:L11_bact:L3_bact:Unknown function:Translation:Protein synthesis:Ribosomal proteins: synthesis and modification:Translation factors:Genetic Information Processing:General:Information storage and processing" 540 "Xaa-Pro aminopeptidase:Leucyl aminopeptidase:Molybdopterin biosynthesis enzyme:Predicted Zn-dependent proteases and their inactivated homologs:Glycosyltransferase:ATPases involved in chromosome partitioning:SAM-dependent methyltransferases:Molybdopterin biosynthesis enzymes:Transcriptional regulator:Urea amidohydrolase (urease) gamma subunit:Predicted ATP-dependent protease:Sortase and related acyltransferases:Transcriptional regulator:Outer membrane protein:Selenocysteine synthase [seryl-tRNASer selenium transferase]:Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains:PEP phosphonomutase and related enzymes:DNA polymerase III, chi subunit:Gluconolactonase:Cell cycle control, cell division, chromosome partitioning:Amino acid transport and metabolism:Carbohydrate transport and metabolism:Coenzyme transport and metabolism:Transcription:Replication, recombination and repair:Cell wall/membrane/envelope biogenesis:Posttranslational modification, protein turnover, chaperones:Purine metabolism:Pyrimidine metabolism:Arginine and proline metabolism:Phosphonate and phosphinate metabolism:Selenocompound metabolism:Glutathione metabolism:Atrazine degradation:Aminoacyl-tRNA biosynthesis:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:Two-component system:DNA replication:Bacterial secretion system:Mismatch repair:Homologous recombination:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:Signal transduction mechanisms:molyb_syn:urease_gam:selA:type_I_sec_TolC:Intracellular trafficking, secretion, and vesicular transport:Nitrogen metabolism:Central intermediary metabolism:Metabolism:Global:Signal Transduction:Membrane Transport:Environmental Information Processing:Metabolism:Replication and Repair:Translation:Genetic Information Processing:Xenobiotics Biodegradation and Metabolism:Metabolism of Other Amino Acids:Amino Acid Metabolism:Poorly characterized:Nucleotide Metabolism:Metabolism:Cellular processes and signaling:Information storage and processing:Porins:Transport and binding proteins:tRNA aminoacylation:Protein synthesis" 541 "Energy production and conversion:Tyrosyl-tRNA synthetase:Predicted membrane protein:Lactoylglutathione lyase and related lyases:Transcriptional regulator:Flavodoxins:Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain:Bacterial nucleoid DNA-binding protein:Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases):Transcriptional regulator:Transcriptional regulators:Predicted metal-dependent hydrolase:Predicted membrane protein:Surface lipoprotein:Uncharacterized protein conserved in bacteria:Activator of osmoprotectant transporter ProP:Cell division protein:Uncharacterized protein conserved in bacteria:Uncharacterized protein conserved in bacteria:Cell cycle control, cell division, chromosome partitioning:Amino acid transport and metabolism:Lipid transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:Replication, recombination and repair:Cell wall/membrane/envelope biogenesis:Fatty acid biosynthesis:Glycerolipid metabolism:Glycerophospholipid metabolism:Pyruvate metabolism:Aminoacyl-tRNA biosynthesis:Biosynthesis of unsaturated fatty acids:Metabolic pathways:Ribosome:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:Function unknown:Signal transduction mechanisms:TIGR00023:glyox_I:tyrS:septum_zipA:trp_arylform:Other:Amino acids and amines:Energy metabolism:Metabolism:Metabolism:Global:Translation:Genetic Information Processing:Lipid Metabolism:Poorly characterized:Carbohydrate Metabolism:Metabolism:Cellular processes and signaling:Information storage and processing:Cell division:Cellular processes:tRNA aminoacylation:Protein synthesis:Biosynthesis:Fatty acid and phospholipid metabolism" 542 "Putative translation initiation inhibitor, yjgF family:Nucleotidyltransferase/DNA polymerase involved in DNA repair:Acetyltransferases:Transcriptional regulator:DNA polymerase III, alpha subunit:Sulfate permease and related transporters (MFS superfamily):ABC-type multidrug transport system, ATPase component:Acyl carrier protein phosphodiesterase:Predicted membrane protein:DNA repair photolyase:Outer membrane protein:Putative NADPH-quinone reductase (modulator of drug activity B):ABC-type uncharacterized transport system involved in gliding motility, auxiliary component:Uncharacterized protein conserved in bacteria:Uncharacterized conserved protein:Lipid transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:Replication, recombination and repair:Cell wall/membrane/envelope biogenesis:Cell motility:Inorganic ion transport and metabolism:General function prediction only:Function unknown:polc:sulP:outer_NodT:chol_sulf_TF:Intracellular trafficking, secretion, and vesicular transport:Defense mechanisms:Information storage and processing:Porins:Anions:Transport and binding proteins:Cellular processes and signaling:DNA metabolism:Metabolism:Poorly characterized:DNA replication, recombination, and repair" 543 "Energy production and conversion:Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase]:Ribosomal protein S11:Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases:Lipoate synthase:Acetolactate synthase, small (regulatory) subunit:Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain:Lipoproteins:ABC-type metal ion transport system, periplasmic component/surface antigen:ABC-type transport system involved in resistance to organic solvents, auxiliary component:Fe-S cluster protector protein:Uncharacterized protein conserved in bacteria:Amino acid transport and metabolism:Coenzyme transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:Cell wall/membrane/envelope biogenesis:Posttranslational modification, protein turnover, chaperones:Inorganic ion transport and metabolism:Valine leucine and isoleucine biosynthesis:Butanoate metabolism:C5-Branched dibasic acid metabolism:Pantothenate and CoA biosynthesis:Lipoic acid metabolism:Aminoacyl-tRNA biosynthesis:Metabolic pathways:Biosynthesis of secondary metabolites:ABC transporters:Two-component system:Ribosome:Secondary metabolites biosynthesis, transport and catabolism:Function unknown:Signal transduction mechanisms:acolac_lg:acolac_sm:gatA:TIGR00363:rlpA:lipA:bact_S11:Metabolism:Carbohydrate Metabolism:Amino Acid Metabolism:Metabolism of Cofactors and Vitamins:Genetic Information Processing:Translation:Environmental Information Processing:Membrane Transport:Signal Transduction:Global:Metabolism:Protein synthesis:tRNA aminoacylation:Ribosomal proteins: synthesis and modification:Amino acid biosynthesis:Pyruvate family:Biosynthesis of cofactors, prosthetic groups, and carriers:Lipoate:Cell envelope:Other:Information storage and processing:Cellular processes and signaling:Metabolism:Poorly characterized" 544 "Acetylglutamate semialdehyde dehydrogenase:Adenylosuccinate lyase:Glutamine amidotransferase:Imidazoleglycerol-phosphate dehydratase:5,10-methylene-tetrahydrofolate dehydrogenase/Methenyl tetrahydrofolate cyclohydrolase:Protein chain release factor A:Ribonuclease D:Superfamily II DNA helicase:ABC-type transport system involved in cytochrome c biogenesis, permease component:Transcriptional regulator:Integral membrane protein CcmA involved in cell shape determination:Predicted flavoproteins:ABC-type transport system involved in cytochrome c biogenesis, permease component:ADP-heptose synthase, bifunctional sugar kinase/adenylyltransferase:Uncharacterized protein conserved in bacteria:ABC-type transport system involved in cytochrome c biogenesis, ATPase component:Amino acid transport and metabolism:Nucleotide transport and metabolism:Coenzyme transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:Replication, recombination and repair:Cell wall/membrane/envelope biogenesis:Posttranslational modification, protein turnover, chaperones:Purine metabolism:Alanine aspartate and glutamate metabolism:Lysine biosynthesis:Arginine and proline metabolism:Histidine metabolism:Lipopolysaccharide biosynthesis:One carbon pool by folate:Carbon fixation pathways in prokaryotes:Aminoacyl-tRNA biosynthesis:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:ABC transporters:RNA degradation:General function prediction only:Function unknown:prfB:cyt_tran_rel:TIGR00275:recQ_fam:purB:ccmA:ccmB:ccmC:rnd:argC:IMP_synth_hisH:TIGR02448:Glutamate family:Energy Metabolism:Nucleotide Metabolism:Amino Acid Metabolism:Glycan Biosynthesis and Metabolism:Metabolism of Cofactors and Vitamins:Genetic Information Processing:Translation:Folding Sorting and Degradation:Environmental Information Processing:Membrane Transport:Global:Metabolism:Purines, pyrimidines, nucleosides, and nucleotides:Purine ribonucleotide biosynthesis:DNA metabolism:DNA replication, recombination, and repair:Transcription:RNA processing:Protein synthesis:Translation factors:Transport and binding proteins:Other:Unknown function:Enzymes of unknown specificity:Amino acid biosynthesis:Metabolism:Histidine family:Information storage and processing:Cellular processes and signaling:Metabolism:Poorly characterized" 545 "Energy production and conversion:Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily):Fucose permease:Threonine dehydrogenase and related Zn-dependent dehydrogenases:Predicted membrane protein:Choline-glycine betaine transporter:Outer membrane protein:Multidrug resistance efflux pump:DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog:FOG: EAL domain:Sugar phosphate permease:ATP-dependent transcriptional regulator:Cytochrome c5:Phospholipase C:Predicted metal-dependent hydrolase:Fe2+-dicitrate sensor, membrane component:Amino acid transport and metabolism:Carbohydrate transport and metabolism:Transcription:Cell wall/membrane/envelope biogenesis:Inorganic ion transport and metabolism:Inositol phosphate metabolism:Glycerophospholipid metabolism:Ether lipid metabolism:Metabolic pathways:RNA polymerase:General function prediction only:Function unknown:Signal transduction mechanisms:GGDEF:bcct:outer_NodT:sigma70-ECF:PC_PLC:Intracellular trafficking, secretion, and vesicular transport:Defense mechanisms:Poorly characterized:Carbohydrate Metabolism:Lipid Metabolism:Genetic Information Processing:Transcription:Global:Metabolism:Transport and binding proteins:Other:Porins:Cellular processes:Pathogenesis:Signal transduction:Other:Information storage and processing:Cellular processes and signaling:Metabolism:Metabolism" 546 "Energy production and conversion:Membrane protease subunits, stomatin/prohibitin homologs:Deoxyribodipyrimidine photolyase:DNA repair exonuclease:Predicted glutathione S-transferase:Transcriptional regulator:Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily):Predicted transcriptional regulators:Rad3-related DNA helicases:Predicted membrane protein:Transcriptional regulator:Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL homologs:Pirin-related protein:Acyl-CoA dehydrogenases:Cytochrome c, mono- and diheme variants:Uncharacterized protein, possibly involved in aromatic compounds catabolism:Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS/CutS homologs:Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain:Choline dehydrogenase and related flavoproteins:DNA-binding HTH domain-containing proteins:Uncharacterized protein conserved in bacteria:Uncharacterized conserved protein:Predicted metal-dependent hydrolase:Predicted O-methyltransferase:Amino acid transport and metabolism:Lipid transport and metabolism:Transcription:Replication, recombination and repair:Posttranslational modification, protein turnover, chaperones:Glycine serine and threonine metabolism:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:Function unknown:Signal transduction mechanisms:unchar_dom_1:sbcd:betA:Amino Acid Metabolism:Metabolism:Adaptations to atypical conditions:Information storage and processing:Cellular processes and signaling:Metabolism:DNA replication, recombination, and repair:Poorly characterized:DNA metabolism:Cellular processes" 547 "Cytosine deaminase and related metal-dependent hydrolases:Predicted metalloprotease:Predicted signal transduction protein with a C-terminal ATPase domain:Bacterial lipocalin:Uncharacterized protein conserved in bacteria:Uncharacterized protein conserved in bacteria:Uncharacterized protein conserved in bacteria:Predicted integral membrane protein:Nucleotide transport and metabolism:Cell wall/membrane/envelope biogenesis:Purine metabolism:Metabolic pathways:Two-component system:General function prediction only:Function unknown:Signal transduction mechanisms:guan_deamin:Poorly characterized:Nucleotide Metabolism:Environmental Information Processing:Signal Transduction:Global:Metabolism:Purines, pyrimidines, nucleosides, and nucleotides:Other:Cellular processes and signaling:Metabolism:Metabolism" 548 "Energy production and conversion:Anaerobic dehydrogenases, typically selenocysteine-containing:Chemotaxis protein histidine kinase and related kinases:Chemotaxis signal transduction protein:Methyl-accepting chemotaxis protein:Methylase of chemotaxis methyl-accepting proteins:Uncharacterized conserved protein:Uncharacterized conserved protein:Putative Ser protein kinase:Nitrate/TMAO reductases, membrane-bound tetraheme cytochrome c subunit:Nitrate reductase cytochrome c-type subunit:Cell motility:Nitrogen metabolism:Microbial metabolism in diverse environments:Two-component system:Bacterial chemotaxis:Function unknown:Signal transduction mechanisms:NAPA:napC_nirT:Cellular processes and signaling:Energy Metabolism:Environmental Information Processing:Signal Transduction:Cellular Processes:Cell Motility:Global:Metabolism:Central intermediary metabolism:Nitrogen metabolism:Metabolism:Metabolism:Poorly characterized" 549 "Replicative DNA helicase:Phosphate/sulphate permeases:Aspartate/tyrosine/aromatic aminotransferase:Membrane GTPase LepA:Adenine/guanine phosphoribosyltransferases and related PRPP-binding proteins:Signal recognition particle GTPase:Predicted dehydrogenase:UDP-N-acetylglucosamine enolpyruvyl transferase:Amino acid transport and metabolism:Nucleotide transport and metabolism:Replication, recombination and repair:Cell wall/membrane/envelope biogenesis:Inorganic ion transport and metabolism:Purine metabolism:Alanine aspartate and glutamate metabolism:Valine leucine and isoleucine biosynthesis:Amino sugar and nucleotide sugar metabolism:Peptidoglycan biosynthesis:Pyruvate metabolism:Metabolic pathways:Biosynthesis of secondary metabolites:DNA replication:Protein export:Bacterial secretion system:General function prediction only:small_GTP:DnaB:ffh:murA:mal_quin_oxido:XPRTase:Intracellular trafficking, secretion, and vesicular transport:Unknown function:Carbohydrate Metabolism:Nucleotide Metabolism:Amino Acid Metabolism:Glycan Biosynthesis and Metabolism:Genetic Information Processing:Folding Sorting and Degradation:Replication and Repair:Environmental Information Processing:Membrane Transport:Global:Metabolism:Energy metabolism:TCA cycle:Purines, pyrimidines, nucleosides, and nucleotides:Salvage of nucleosides and nucleotides:DNA metabolism:DNA replication, recombination, and repair:Protein fate:Protein and peptide secretion and trafficking:Metabolism:General:Cell envelope:Biosynthesis and degradation of murein sacculus and peptidoglycan:Information storage and processing:Cellular processes and signaling:Metabolism:Poorly characterized" 550 "Energy production and conversion:Predicted Na+-dependent transporter:Peroxiredoxin:Predicted phosphatases:Transcriptional regulator:Signal transduction histidine kinase:ABC-type amino acid transport/signal transduction systems, periplasmic component/domain:Cation/multidrug efflux pump:Membrane-fusion protein:Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases):Putative threonine efflux protein:Choline-glycine betaine transporter:Transcriptional regulator:DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog:Transcriptional regulators:NADH:flavin oxidoreductases, Old Yellow Enzyme family:AraC-type DNA-binding domain-containing proteins:Predicted aminopeptidases:Uncharacterized protein conserved in bacteria:Uncharacterized conserved protein:Uncharacterized protein conserved in bacteria:Fe2+-dicitrate sensor, membrane component:Uncharacterized protein conserved in archaea:Signal transduction histidine kinase regulating C4-dicarboxylate transport system:Ornithine/acetylornithine aminotransferase:Amino acid transport and metabolism:Lipid transport and metabolism:Transcription:Cell wall/membrane/envelope biogenesis:Posttranslational modification, protein turnover, chaperones:Inorganic ion transport and metabolism:Lysine biosynthesis:Arginine and proline metabolism:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:Two-component system:RNA polymerase:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:Function unknown:Signal transduction mechanisms:bcct:autotrans_barl:HAD-SF-IA-v3:RND_mfp:sigma70-ECF:Defense mechanisms:Unknown function:Pathogenesis:Cellular processes:Other:Unknown substrate:Transport and binding proteins:Metabolism:Global:Signal Transduction:Environmental Information Processing:Transcription:Genetic Information Processing:Metabolism:Amino Acid Metabolism:Poorly characterized:Metabolism:Cellular processes and signaling:Information storage and processing:Enzymes of unknown specificity" 551 "Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain:Transcriptional regulator:Glutathione S-transferase:Demethylmenaquinone methyltransferase:Selenophosphate synthase:MoxR-like ATPases:Cell wall-associated hydrolases (invasion-associated proteins):Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains:Predicted ATPase:Ubiquinone biosynthesis protein COQ7:Negative regulator of sigma E activity:Uncharacterized protein conserved in bacteria:Positive regulator of sigma E activity:Predicted periplasmic/secreted protein:Predicted O-methyltransferase:Isocitrate dehydrogenase kinase/phosphatase:Amino acid transport and metabolism:Coenzyme transport and metabolism:Transcription:Cell wall/membrane/envelope biogenesis:Posttranslational modification, protein turnover, chaperones:Ubiquinone and other terpenoid-quinone biosynthesis:Histidine metabolism:Tyrosine metabolism:Selenocompound metabolism:Polycyclic aromatic hydrocarbon degradation:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:General function prediction only:Function unknown:Signal transduction mechanisms:selD:NOT-MenG:degP_htrA_DO:tRNA_sel_U_synt:Cellular processes and signaling:Amino Acid Metabolism:Metabolism of Other Amino Acids:Metabolism of Cofactors and Vitamins:Xenobiotics Biodegradation and Metabolism:Global:Metabolism:Protein synthesis:tRNA and rRNA base modification:Protein fate:Degradation of proteins, peptides, and glycopeptides:Unknown function:General:Information storage and processing:Metabolism:Metabolism:Poorly characterized" 552 "Signal recognition particle GTPase:DNA polymerase III, alpha subunit:Predicted Zn-dependent peptidases:Signal transduction histidine kinase:Cell division protein FtsI/penicillin-binding protein 2:Sec-independent protein secretion pathway component TatC:Low specificity phosphatase (HAD superfamily):Predicted ATPase involved in cell division:Membrane glycosyltransferase:Uncharacterized protein conserved in bacteria:Uncharacterized protein conserved in bacteria:Cell cycle control, cell division, chromosome partitioning:Replication, recombination and repair:Cell wall/membrane/envelope biogenesis:Purine metabolism:Pyrimidine metabolism:Lipopolysaccharide biosynthesis:Peptidoglycan biosynthesis:Metabolic pathways:ABC transporters:DNA replication:Protein export:Bacterial secretion system:Mismatch repair:Homologous recombination:General function prediction only:Function unknown:Signal transduction mechanisms:ftsY:polc:tatC:YrbI-phosphatas:FtsE:pbp2_mrdA:Intracellular trafficking, secretion, and vesicular transport:Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides:Nucleotide Metabolism:Glycan Biosynthesis and Metabolism:Genetic Information Processing:Folding Sorting and Degradation:Replication and Repair:Environmental Information Processing:Membrane Transport:Global:Metabolism:DNA metabolism:DNA replication, recombination, and repair:Protein fate:Protein and peptide secretion and trafficking:Cellular processes:Cell division:Cell envelope:Biosynthesis and degradation of murein sacculus and peptidoglycan:Metabolism:Information storage and processing:Cellular processes and signaling:Poorly characterized" 553 "Fe2+ transport system protein B:Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis:Spermidine synthase:Nucleoside-diphosphate-sugar epimerases:Glycosyltransferases involved in cell wall biogenesis:Signal transduction histidine kinase:Predicted xylanase/chitin deacetylase:Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain:Predicted UDP-glucose 6-dehydrogenase:S-adenosylmethionine decarboxylase:4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family:Fe2+ transport system protein A:Amino acid transport and metabolism:Carbohydrate transport and metabolism:Transcription:Cell wall/membrane/envelope biogenesis:Inorganic ion transport and metabolism:Pentose and glucuronate interconversions:Ascorbate and aldarate metabolism:Cysteine and methionine metabolism:Arginine and proline metabolism:beta-Alanine metabolism:Glutathione metabolism:Starch and sucrose metabolism:Amino sugar and nucleotide sugar metabolism:Metabolic pathways:Biosynthesis of secondary metabolites:Two-component system:Signal transduction mechanisms:feoB:NDP-sugDHase:SAM_DCase_Bsu:Metabolism:Global:Signal Transduction:Environmental Information Processing:Metabolism of Other Amino Acids:Amino Acid Metabolism:Metabolism:Cations and iron carrying compounds:Carbohydrate Metabolism:Information storage and processing:Cellular processes and signaling:Metabolism:Transport and binding proteins:Polyamine biosynthesis:Central intermediary metabolism" 554 "Zonula occludens toxin:General function prediction only:Poorly characterized" 555 "Energy production and conversion:Glutamate dehydrogenase/leucine dehydrogenase:Lactoylglutathione lyase and related lyases:FOG: CheY-like receiver:Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain:Glycine cleavage system regulatory protein:Periplasmic nitrate reductase system, NapE component:Amino acid transport and metabolism:Transcription:Valine leucine and isoleucine degradation:Valine leucine and isoleucine biosynthesis:Nitrogen metabolism:Metabolic pathways:Biosynthesis of secondary metabolites:Two-component system:Bacterial chemotaxis:Signal transduction mechanisms:nitrate_rd_NapE:Electron transport:Information storage and processing:Cellular processes and signaling:Metabolism:Energy metabolism:Metabolism:Metabolism:Global:Cell Motility:Cellular Processes:Signal Transduction:Environmental Information Processing:Amino Acid Metabolism:Energy Metabolism"