Methanococcus maripaludis S2 Module 9 Residual: 0.44

Residual: 0.44 Score: -12.9121 version: mmp_cmonkey_11_Oct_11
MMP0057 FO synthase, subunit CofH (NCBI)

Details for MMP0057 - FO synthase, subunit CofH (NCBI)

GO Terms: GO:0008152, GO:0003824, GO:0051536

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP0057

Tuberculist Genomic Region

MMP0824 coenzyme F420-non-reducing hydrogenase subunit beta (NCBI)

Details for MMP0824 - coenzyme F420-non-reducing hydrogenase subunit beta (NCBI)

GO Terms: GO:0006118, GO:0009055, GO:0051536

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP0824

Tuberculist Genomic Region

MMP0138 formate dehydrogenase alpha subunit (NCBI)

Details for MMP0138 - formate dehydrogenase alpha subunit (NCBI)

GO Terms: GO:0006118, GO:0015942, GO:0009326, GO:0030151, GO:0008863

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP0138

Tuberculist Genomic Region

MMP1053 heterodisulfide reductase; subunit B2 (NCBI)

Details for MMP1053 - heterodisulfide reductase; subunit B2 (NCBI)

GO Terms: GO:0051912

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP1053

Tuberculist Genomic Region

MMP0139 formate dehydrogenase beta subunit (NCBI)

Details for MMP0139 - formate dehydrogenase beta subunit (NCBI)

GO Terms: GO:0006118, GO:0009326, GO:0051536, GO:0008863, GO:0009055

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP0139

Tuberculist Genomic Region

MMP1054 heterodisulfide reductase; subunit C2 (NCBI)

Details for MMP1054 - heterodisulfide reductase; subunit C2 (NCBI)

GO Terms: GO:0006118, GO:0051912, GO:0051536, GO:0009055

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP1054

Tuberculist Genomic Region

MMP0172 hypothetical protein (NCBI)

Details for MMP0172 - hypothetical protein (NCBI)

GO Terms: NA

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP0172

Tuberculist Genomic Region

MMP1297 formate dehydrogenase beta subunit (NCBI)

Details for MMP1297 - formate dehydrogenase beta subunit (NCBI)

GO Terms: GO:0006118, GO:0009326, GO:0008863, GO:0009055, GO:0051536

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP1297

Tuberculist Genomic Region

MMP0347 hypothetical protein (NCBI)

Details for MMP0347 - hypothetical protein (NCBI)

GO Terms: NA

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP0347

Tuberculist Genomic Region

MMP1298 formate dehydrogenase alpha subunit (NCBI)

Details for MMP1298 - formate dehydrogenase alpha subunit (NCBI)

GO Terms: GO:0006118, GO:0015942, GO:0009326, GO:0008863, GO:0030151

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP1298

Tuberculist Genomic Region

MMP0486 conserved hypothetical protein (NCBI)

Details for MMP0486 - conserved hypothetical protein (NCBI)

GO Terms: NA

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP0486

Tuberculist Genomic Region

MMP1299 carbonic anhydrase (NCBI)

Details for MMP1299 - carbonic anhydrase (NCBI)

GO Terms: GO:0015976, GO:0008270, GO:0004089

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP1299

Tuberculist Genomic Region

MMP0791 Transcriptional regulator, TetR Family Member (NCBI)

Details for MMP0791 - Transcriptional regulator, TetR Family Member (NCBI)

GO Terms: GO:0006355, GO:0016481, GO:0003700, GO:0016566

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP0791

Tuberculist Genomic Region

MMP1300 hypothetical protein (NCBI)

Details for MMP1300 - hypothetical protein (NCBI)

GO Terms: NA

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP1300

Tuberculist Genomic Region

MMP0792 membrane protein (NCBI)

Details for MMP0792 - membrane protein (NCBI)

GO Terms: GO:0006508, GO:0008451

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP0792

Tuberculist Genomic Region

MMP1301 Formate transporter (NCBI)

Details for MMP1301 - Formate transporter (NCBI)

GO Terms: GO:0006810, GO:0016020, GO:0005215

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP1301

Tuberculist Genomic Region

MMP0793 possible predicted protein (NCBI)

Details for MMP0793 - possible predicted protein (NCBI)

GO Terms: NA

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP0793

Tuberculist Genomic Region

MMP1302 hypothetical protein (NCBI)

Details for MMP1302 - hypothetical protein (NCBI)

GO Terms: NA

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP1302

Tuberculist Genomic Region

MMP0818 coenzyme F420-reducing hydrogenase subunit gamma (NCBI)

Details for MMP0818 - coenzyme F420-reducing hydrogenase subunit gamma (NCBI)

GO Terms: GO:0006120, GO:0008137, GO:0051536, GO:0051539

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP0818

Tuberculist Genomic Region

MMP1378 hypothetical protein (NCBI)

Details for MMP1378 - hypothetical protein (NCBI)

GO Terms: NA

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP1378

Tuberculist Genomic Region

MMP0819 coenzyme F420-reducing hydrogenase subunit delta (NCBI)

Details for MMP0819 - coenzyme F420-reducing hydrogenase subunit delta (NCBI)

GO Terms: GO:0006464, GO:0008047, GO:0008233

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP0819

Tuberculist Genomic Region

MMP1642 ATP/GTP-binding site motif A (P-loop):Small GTP-binding protein domain (NCBI)

Details for MMP1642 - ATP/GTP-binding site motif A (P-loop):Small GTP-binding protein domain (NCBI)

GO Terms: GO:0015684, GO:0005622, GO:0016021, GO:0009276, GO:0005525, GO:0015093

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP1642

Tuberculist Genomic Region

MMP0822 coenzyme F420-non-reducing hydrogenase subunit gamma (NCBI)

Details for MMP0822 - coenzyme F420-non-reducing hydrogenase subunit gamma (NCBI)

GO Terms: GO:0006120, GO:0008137, GO:0051539

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP0822

Tuberculist Genomic Region

MMP0799 Transcriptional regulator, TetR Family Member (NCBI)

Details for MMP0799 - Transcriptional regulator, TetR Family Member (NCBI)

GO Terms: GO:0006355, GO:0016481, GO:0003700, GO:0016566

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP0799

Tuberculist Genomic Region

Motif 1: e-value: 0.21 e-value: 5.2
Regulator Interaction Influence Weight Other Influences

H2

down-regulates -0.51
conserved hypothetical archaeal protein (NCBI)
down-regulates -0.24
putative transricptional regulator (NCBI)
up-regulates 0.20
Category: BP
Category GO ID GO Term Annotated Expected Significant p-value
BP GO:0006464 cellular protein modification process 5 0.03 1 0.0260
BP GO:0036211 protein modification process 5 0.03 1 0.0260
BP GO:0043412 macromolecule modification 5 0.03 1 0.0260
Category: MF
Category GO ID GO Term Annotated Expected Significant p-value
MF GO:0051539 4 iron, 4 sulfur cluster binding 37 0.67 5 0.0003
MF GO:0051536 iron-sulfur cluster binding 67 1.21 6 0.0006
MF GO:0051540 metal cluster binding 67 1.21 6 0.0006
MF GO:0008863 formate dehydrogenase (NAD+) activity 3 0.05 2 0.0009
MF GO:0016620 oxidoreductase activity, acting on the a... 5 0.09 2 0.0030
MF GO:0016491 oxidoreductase activity 78 1.41 4 0.0439
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