Methanococcus maripaludis S2 Module 61 Residual: 0.23

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Summary

Residual: 0.23 Score: -16.874 version: mmp_cmonkey_11_Oct_11

Members

MMP0043 isopentenyl-diphosphate delta-isomerase related protein (NCBI)

Details for MMP0043 - isopentenyl-diphosphate delta-isomerase related protein (NCBI)

GO Terms: GO:0006118, GO:0008299, GO:0005737, GO:0016491, GO:0004452, GO:0010181

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP0043

Tuberculist Genomic Region

MMP0442 conserved hypothetical protein (NCBI)

Details for MMP0442 - conserved hypothetical protein (NCBI)

GO Terms: NA

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP0442

Tuberculist Genomic Region

MMP0060 Ribosomal LX protein (NCBI)

Details for MMP0060 - Ribosomal LX protein (NCBI)

GO Terms: GO:0006412, GO:0005840, GO:0003735

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP0060

Tuberculist Genomic Region

MMP1208 translation initiation factor aIF-2, subunit gamma (NCBI)

Details for MMP1208 - translation initiation factor aIF-2, subunit gamma (NCBI)

GO Terms: GO:0005525, GO:0003924

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP1208

Tuberculist Genomic Region

MMP0061 Translation initiation factor IF6 (NCBI)

Details for MMP0061 - Translation initiation factor IF6 (NCBI)

GO Terms: GO:0042256, GO:0043022

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP0061

Tuberculist Genomic Region

MMP1399 Aspartate/glutamate/uridylate kinase (NCBI)

Details for MMP1399 - Aspartate/glutamate/uridylate kinase (NCBI)

GO Terms: GO:0008652

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP1399

Tuberculist Genomic Region

MMP0155 conserved hypothetical protein (NCBI)

Details for MMP0155 - conserved hypothetical protein (NCBI)

GO Terms: NA

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP0155

Tuberculist Genomic Region

MMP1434 LSU ribosomal protein L24A (NCBI)

Details for MMP1434 - LSU ribosomal protein L24A (NCBI)

GO Terms: GO:0006355, GO:0003711

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP1434

Tuberculist Genomic Region

MMP0249 Ribosomal L37ae protein (NCBI)

Details for MMP0249 - Ribosomal L37ae protein (NCBI)

GO Terms: GO:0006412, GO:0005840, GO:0003735

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP0249

Tuberculist Genomic Region

MMP1443 GTP1/OBG family:ATP/GTP-binding site motif A (P-loop):TGS domain:Small GTP-binding protein domain (NCBI)

Details for MMP1443 - GTP1/OBG family:ATP/GTP-binding site motif A (P-loop):TGS domain:Small GTP-binding protein domain (NCBI)

GO Terms: GO:0015684, GO:0005622, GO:0016021, GO:0009276, GO:0005525, GO:0015093

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP1443

Tuberculist Genomic Region

MMP0250 conserved hypothetical protein (NCBI)

Details for MMP0250 - conserved hypothetical protein (NCBI)

GO Terms: NA

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP0250

Tuberculist Genomic Region

MMP1444 Metallopeptidase family M24:Methionine aminopeptidase:Methionine aminopeptidase, subfamily 2 (NCBI)

Details for MMP1444 - Metallopeptidase family M24:Methionine aminopeptidase:Methionine aminopeptidase, subfamily 2 (NCBI)

GO Terms: GO:0006508, GO:0004239

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP1444

Tuberculist Genomic Region

MMP0384 conserved hypothetical protein (NCBI)

Details for MMP0384 - conserved hypothetical protein (NCBI)

GO Terms: NA

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP0384

Tuberculist Genomic Region

MMP1445 GMP synthase (glutamine-hydrolyzing) (NCBI)

Details for MMP1445 - GMP synthase (glutamine-hydrolyzing) (NCBI)

GO Terms: GO:0006177, GO:0006541, GO:0005524, GO:0003922

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP1445

Tuberculist Genomic Region

MMP0457 Probable ATP dependent RNA helicase (NCBI)

Details for MMP0457 - Probable ATP dependent RNA helicase (NCBI)

GO Terms: GO:0003676, GO:0003677, GO:0005524, GO:0008026

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP0457

Tuberculist Genomic Region

MMP1472 conserved hypothetical protein (NCBI)

Details for MMP1472 - conserved hypothetical protein (NCBI)

GO Terms: NA

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP1472

Tuberculist Genomic Region

MMP1579 Probable SSU ribosomal protein S15P/S13E (NCBI)

Details for MMP1579 - Probable SSU ribosomal protein S15P/S13E (NCBI)

GO Terms: GO:0006412, GO:0005840, GO:0003735

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP1579

Tuberculist Genomic Region

MMP0062 Ribosomal protein L31e (NCBI)

Details for MMP0062 - Ribosomal protein L31e (NCBI)

GO Terms: GO:0006412, GO:0005840, GO:0003735

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP0062

Tuberculist Genomic Region

MMP0045 bifunctional short chain isoprenyl diphosphate synthase (NCBI)

Details for MMP0045 - bifunctional short chain isoprenyl diphosphate synthase (NCBI)

GO Terms: GO:0008299

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP0045

Tuberculist Genomic Region

MMP1400 M. jannaschii predicted coding region MJ0458.1 (NCBI)

Details for MMP1400 - M. jannaschii predicted coding region MJ0458.1 (NCBI)

GO Terms: NA

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP1400

Tuberculist Genomic Region

MMP0440 DNA-directed RNA polymerase subunit E' (NCBI)

Details for MMP0440 - DNA-directed RNA polymerase subunit E' (NCBI)

GO Terms: GO:0006350, GO:0005634, GO:0003677, GO:0003901, GO:0003723, GO:0003902, GO:0003899, GO:0003900

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP0440

Tuberculist Genomic Region

MMP1401 translation elongation factor aEF-1 beta (NCBI)

Details for MMP1401 - translation elongation factor aEF-1 beta (NCBI)

GO Terms: GO:0006414, GO:0005853, GO:0003746, GO:0008547, GO:0003924

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP1401

Tuberculist Genomic Region

MMP0441 DNA-directed RNA polymerase subunit E (NCBI)

Details for MMP0441 - DNA-directed RNA polymerase subunit E (NCBI)

GO Terms: GO:0045941, GO:0005634, GO:0003899, GO:0003900, GO:0008159, GO:0003901, GO:0008270, GO:0003902

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP0441

Tuberculist Genomic Region

MMP1403 LSU ribosomal protein L22P (NCBI)

Details for MMP1403 - LSU ribosomal protein L22P (NCBI)

GO Terms: GO:0006412, GO:0015934, GO:0003735

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP1403

Tuberculist Genomic Region

Displaying 1 - 24 of 24

Motifs

Motif 1: e-value: 5600 e-value: 7800

Module Plots

Regulation

Regulator Interaction Influence Weight Other Influences

MMP0568

transcriptional regulator related protein (NCBI)
 up-regulates 0.65

MMP0568

MMP0097

Transcriptional regulator protein, Helix-turn-helix motif (NCBI)
 down-regulates -0.42

MMP0097

MMP1015

Transcription factor CBF/NF-Y/archaeal histone:Histone-fold/TFIID-TAF/NF-Y domain (NCBI)
 down-regulates -0.32

MMP1015

MMP0052

Conserved Hypothetical protein with 2 CBS domains (NCBI)
 down-regulates -0.29

MMP0052

MMP0097

Transcriptional regulator protein, Helix-turn-helix motif (NCBI)

MMP1015

Transcription factor CBF/NF-Y/archaeal histone:Histone-fold/TFIID-TAF/NF-Y domain (NCBI)
 down-regulates -0.26

MMP0097

MMP1015

MMP0052

Conserved Hypothetical protein with 2 CBS domains (NCBI)

MMP0257

TATA-binding protein (TBP) (NCBI)
 up-regulates 0.25

MMP0052

MMP0257

GO Enrichment

Category: BP
Category GO ID GO Term Annotated Expected Significant p-value
BP GO:0022613 ribonucleoprotein complex biogenesis 3 0.05 2 0.0005
BP GO:0042254 ribosome biogenesis 3 0.05 2 0.0005
BP GO:0044085 cellular component biogenesis 6 0.09 2 0.0024
BP GO:0071840 cellular component organization or bioge... 6 0.09 2 0.0024
Category: CC
Category GO ID GO Term Annotated Expected Significant p-value
CC GO:0044444 cytoplasmic part 34 0.75 4 0.0011
CC GO:0032991 macromolecular complex 41 0.91 4 0.0023
CC GO:0005737 cytoplasm 67 1.48 4 0.0177
CC GO:0005840 ribosome 32 0.71 3 0.0179
CC GO:0043226 organelle 32 0.71 3 0.0179
CC GO:0043228 non-membrane-bounded organelle 32 0.71 3 0.0179
CC GO:0043229 intracellular organelle 32 0.71 3 0.0179
CC GO:0043232 intracellular non-membrane-bounded organ... 32 0.71 3 0.0179
CC GO:0044424 intracellular part 71 1.57 4 0.0225
CC GO:0030529 ribonucleoprotein complex 36 0.80 3 0.0253
CC GO:0005622 intracellular 76 1.68 4 0.0297
CC GO:0005623 cell 85 1.88 4 0.0468
CC GO:0044464 cell part 85 1.88 4 0.0468
Category: MF
Category GO ID GO Term Annotated Expected Significant p-value
MF GO:0070180 large ribosomal subunit rRNA binding 6 0.10 2 0.0038
MF GO:0016772 transferase activity, transferring phosp... 12 0.20 2 0.0157
MF GO:0097159 organic cyclic compound binding 329 5.53 9 0.0472
MF GO:1901363 heterocyclic compound binding 329 5.53 9 0.0472
MF GO:0005525 GTP binding 22 0.37 2 0.0499
MF GO:0019001 guanyl nucleotide binding 22 0.37 2 0.0499
MF GO:0032561 guanyl ribonucleotide binding 22 0.37 2 0.0499

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