Methanococcus maripaludis S2 Module 78 Residual: 0.39

Residual: 0.39 Score: -12.1023 version: mmp_cmonkey_11_Oct_11
MMP0381 3-isopropylmalate dehydratase small subunit Related (NCBI)

Details for MMP0381 - 3-isopropylmalate dehydratase small subunit Related (NCBI)

GO Terms: GO:0009098, GO:0009316, GO:0003861

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP0381

Tuberculist Genomic Region

MMP0399 Peptidase family M48 (NCBI)

Details for MMP0399 - Peptidase family M48 (NCBI)

GO Terms: GO:0006508, GO:0016020, GO:0004222

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP0399

Tuberculist Genomic Region

MMP0704 ParA type ATPase (NCBI)

Details for MMP0704 - ParA type ATPase (NCBI)

GO Terms: NA

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP0704

Tuberculist Genomic Region

MMP0400 Conserved hypothetical protein (NCBI)

Details for MMP0400 - Conserved hypothetical protein (NCBI)

GO Terms: GO:0008152, GO:0016597

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP0400

Tuberculist Genomic Region

MMP0290 conserved hypothetical archaeal protein (NCBI)

Details for MMP0290 - conserved hypothetical archaeal protein (NCBI)

GO Terms: GO:0010181

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP0290

Tuberculist Genomic Region

MMP0410 Phosphoribosyltransferase:Purine/pyrimidine phosphoribosyl transferase (NCBI)

Details for MMP0410 - Phosphoribosyltransferase:Purine/pyrimidine phosphoribosyl transferase (NCBI)

GO Terms: GO:0009116, GO:0009165, GO:0000287, GO:0004749

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP0410

Tuberculist Genomic Region

MMP0308 conserved hypothetical archaeal protein (NCBI)

Details for MMP0308 - conserved hypothetical archaeal protein (NCBI)

GO Terms: GO:0008033, GO:0005737, GO:0005515, GO:0016783

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP0308

Tuberculist Genomic Region

MMP0500 Iron-sulfur flavoprotein-related (NCBI)

Details for MMP0500 - Iron-sulfur flavoprotein-related (NCBI)

GO Terms: GO:0016491, GO:0050662

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP0500

Tuberculist Genomic Region

MMP0309 intracellular sulfur reduction related protein (NCBI)

Details for MMP0309 - intracellular sulfur reduction related protein (NCBI)

GO Terms: NA

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP0309

Tuberculist Genomic Region

MMP1023 Transcriptional regulator, TetR Family Member (NCBI)

Details for MMP1023 - Transcriptional regulator, TetR Family Member (NCBI)

GO Terms: GO:0006355, GO:0016481, GO:0003700, GO:0016566

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP1023

Tuberculist Genomic Region

MMP0355 conserved hypothetical protein (NCBI)

Details for MMP0355 - conserved hypothetical protein (NCBI)

GO Terms: NA

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP0355

Tuberculist Genomic Region

MMP1116 endoglucanase (NCBI)

Details for MMP1116 - endoglucanase (NCBI)

GO Terms: GO:0008237, GO:0008810

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP1116

Tuberculist Genomic Region

MMP0359 Glycosyl transferase, family 2 (NCBI)

Details for MMP0359 - Glycosyl transferase, family 2 (NCBI)

GO Terms: NA

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP0359

Tuberculist Genomic Region

MMP1129 Peptidyl-prolyl cis-trans isomerase, cyclophilin type (NCBI)

Details for MMP1129 - Peptidyl-prolyl cis-trans isomerase, cyclophilin type (NCBI)

GO Terms: GO:0006457, GO:0030051, GO:0042027, GO:0003755, GO:0004600

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP1129

Tuberculist Genomic Region

MMP0377 isoleucyl-tRNA synthetase related (NCBI)

Details for MMP0377 - isoleucyl-tRNA synthetase related (NCBI)

GO Terms: GO:0006260, GO:0003677, GO:0003887

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP0377

Tuberculist Genomic Region

MMP1137 Lrp-Like Transcriptional regulatory proteins, AsnC family (NCBI)

Details for MMP1137 - Lrp-Like Transcriptional regulatory proteins, AsnC family (NCBI)

GO Terms: GO:0006355, GO:0005622, GO:0005506, GO:0003700, GO:0043565

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP1137

Tuberculist Genomic Region

MMP0382 RNase L inhibitor (NCBI)

Details for MMP0382 - RNase L inhibitor (NCBI)

GO Terms: GO:0006118, GO:0005524, GO:0009055, GO:0016887, GO:0051536

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP0382

Tuberculist Genomic Region

MMP1138 Hydroxyethylthiazole kinase family (NCBI)

Details for MMP1138 - Hydroxyethylthiazole kinase family (NCBI)

GO Terms: GO:0009228, GO:0004417

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP1138

Tuberculist Genomic Region

MMP0385 uridylate kinase (NCBI)

Details for MMP0385 - uridylate kinase (NCBI)

GO Terms: GO:0006221, GO:0008652, GO:0009041

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP0385

Tuberculist Genomic Region

MMP1139 Thiamine monophosphate synthase (NCBI)

Details for MMP1139 - Thiamine monophosphate synthase (NCBI)

GO Terms: GO:0009228, GO:0004789

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP1139

Tuberculist Genomic Region

MMP0391 Aspartate aminotransferase (NCBI)

Details for MMP0391 - Aspartate aminotransferase (NCBI)

GO Terms: GO:0008152, GO:0008483, GO:0030170

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP0391

Tuberculist Genomic Region

MMP1352 NAD binding site:TonB-dependent receptor protein:Thiamine biosynthesis Thi4 protein (NCBI)

Details for MMP1352 - NAD binding site:TonB-dependent receptor protein:Thiamine biosynthesis Thi4 protein (NCBI)

GO Terms: GO:0006118, GO:0009228, GO:0016491

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP1352

Tuberculist Genomic Region

MMP0396 Enolase (NCBI)

Details for MMP0396 - Enolase (NCBI)

GO Terms: GO:0006096, GO:0000015, GO:0004634

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP0396

Tuberculist Genomic Region

MMP1589 Carbamoyl-phosphate synthase small chain (NCBI)

Details for MMP1589 - Carbamoyl-phosphate synthase small chain (NCBI)

GO Terms: GO:0006807, GO:0006541, GO:0009058, GO:0005524, GO:0004088

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP1589

Tuberculist Genomic Region

MMP0397 Alanyl-tRNA synthetase (NCBI)

Details for MMP0397 - Alanyl-tRNA synthetase (NCBI)

GO Terms: GO:0006419, GO:0005737, GO:0003676, GO:0004813, GO:0016787, GO:0005524

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP0397

Tuberculist Genomic Region

Motif 1: e-value: 1.3 e-value: 950
Regulator Interaction Influence Weight Other Influences
Response regulator receiver (NCBI)
down-regulates -0.36
conserved hypothetical archeal protein (NCBI)
up-regulates 0.33
conserved hypothetical archeal protein (NCBI)

H2

up-regulates 0.21
Conserved Hypothetical protein with 2 CBS domains (NCBI)
Response regulator receiver (NCBI)
down-regulates -0.17
LysR family member (NCBI)
up-regulates 0.13
Category: BP
Category GO ID GO Term Annotated Expected Significant p-value
BP GO:0006213 pyrimidine nucleoside metabolic process 8 0.12 2 0.0045
BP GO:0006220 pyrimidine nucleotide metabolic process 8 0.12 2 0.0045
BP GO:0006221 pyrimidine nucleotide biosynthetic proce... 8 0.12 2 0.0045
BP GO:0009218 pyrimidine ribonucleotide metabolic proc... 8 0.12 2 0.0045
BP GO:0009220 pyrimidine ribonucleotide biosynthetic p... 8 0.12 2 0.0045
BP GO:0046131 pyrimidine ribonucleoside metabolic proc... 8 0.12 2 0.0045
BP GO:0046132 pyrimidine ribonucleoside biosynthetic p... 8 0.12 2 0.0045
BP GO:0046134 pyrimidine nucleoside biosynthetic proce... 8 0.12 2 0.0045
BP GO:0009163 nucleoside biosynthetic process 13 0.20 2 0.0123
BP GO:0042455 ribonucleoside biosynthetic process 13 0.20 2 0.0123
BP GO:0072527 pyrimidine-containing compound metabolic... 13 0.20 2 0.0123
BP GO:0072528 pyrimidine-containing compound biosynthe... 13 0.20 2 0.0123
BP GO:1901659 glycosyl compound biosynthetic process 13 0.20 2 0.0123
BP GO:0009119 ribonucleoside metabolic process 15 0.23 2 0.0164
BP GO:0009116 nucleoside metabolic process 16 0.25 2 0.0187
BP GO:1901657 glycosyl compound metabolic process 16 0.25 2 0.0187
BP GO:0009260 ribonucleotide biosynthetic process 25 0.39 2 0.0451
BP GO:0046390 ribose phosphate biosynthetic process 25 0.39 2 0.0451
BP GO:0009141 nucleoside triphosphate metabolic proces... 3 0.05 1 0.0464
BP GO:0009199 ribonucleoside triphosphate metabolic pr... 3 0.05 1 0.0464
BP GO:0009259 ribonucleotide metabolic process 26 0.41 2 0.0487
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