Module Functions 1 "Energy production and conversion:Superfamily I DNA and RNA helicases:DNA primase (bacterial type):Nitroreductase:Methyl-accepting chemotaxis protein:ABC-type multidrug transport system, ATPase and permease components:Transcriptional regulator:Acetyltransferases, including N-acetylases of ribosomal proteins:Tfp pilus assembly protein PilF:Predicted glycosyl hydrolase:Uncharacterized protein conserved in bacteria:Translation, ribosomal structure and biogenesis:Transcription:Replication, recombination and repair:Cell motility:General function prediction only:Function unknown:Signal transduction mechanisms:Intracellular trafficking, secretion, and vesicular transport:Defense mechanisms:Information storage and processing:Poorly characterized:Metabolism:Cellular processes and signaling" 2 "Energy production and conversion:Predicted GTPase, probable translation factor:Phenylalanyl-tRNA synthetase alpha subunit:Phenylalanyl-tRNA synthetase beta subunit:Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), A subunit:UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N-acetylglucosamine-1-phosphate transferase:cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases:UDP-N-acetylmuramyl tripeptide synthase:UDP-N-acetylmuramyl pentapeptide synthase:Bacterial cell division membrane protein:Inorganic pyrophosphatase/exopolyphosphatase:Thiamine pyrophosphokinase:Cell division septal protein:Cell shape-determining protein:Permeases of the major facilitator superfamily:Cell cycle control, cell division, chromosome partitioning:Coenzyme transport and metabolism:Translation, ribosomal structure and biogenesis:Replication, recombination and repair:Cell wall/membrane/envelope biogenesis:General function prediction only:Signal transduction mechanisms:TIGR00092:mreC:mraY:pheS:pheT_bact:murE:murF:thi_PPkinase:ftsW:shape_MreD:Biosynthesis and degradation of murein sacculus and peptidoglycan:Cell envelope:Thiamine:Biosynthesis of cofactors, prosthetic groups, and carriers:General:Poorly characterized:Cell division:Cellular processes:tRNA aminoacylation:Protein synthesis:Unknown function:Metabolism:Cellular processes and signaling:Information storage and processing" 3 "Energy production and conversion:Guanylate kinase:Superfamily I DNA and RNA helicases:NAD-dependent DNA ligase (contains BRCT domain type II):4-hydroxybenzoate polyprenyltransferase and related prenyltransferases:Glycosyltransferases involved in cell wall biogenesis:DNA polymerase sliding clamp subunit (PCNA homolog):ATPase involved in DNA replication initiation:Mg2+ and Co2+ transporters:Predicted permease:Coproporphyrinogen III oxidase and related Fe-S oxidoreductases:Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain:Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs:RecG-like helicase:Recombinational DNA repair protein (RecF pathway):Uncharacterized stress-induced protein:Cell division septal protein:Uncharacterized conserved protein:Tartrate dehydratase alpha subunit/Fumarate hydratase class I, N-terminal domain:SOS-response transcriptional repressors (RecA-mediated autopeptidases):DNA repair proteins:Uncharacterized protein conserved in bacteria:Amino acid transport and metabolism:Nucleotide transport and metabolism:Coenzyme transport and metabolism:Transcription:Replication, recombination and repair:Cell wall/membrane/envelope biogenesis:Inorganic ion transport and metabolism:General function prediction only:Function unknown:Signal transduction mechanisms:TIGR00255:IMPACT_YIGZ:DnaA:hemN_rel:dnlj:radc:reco:recG:dnan:ttdA_fumA_fumB:pcrA:guanyl_kin:DNA metabolism:Nucleotide and nucleoside interconversions:Purines, pyrimidines, nucleosides, and nucleotides:Cellular processes and signaling:Poorly characterized:Information storage and processing:Metabolism:Heme, porphyrin, and cobalamin:Biosynthesis of cofactors, prosthetic groups, and carriers:General:Unknown function:Conserved:Hypothetical proteins:DNA replication, recombination, and repair" 4 "Energy production and conversion:Excinuclease ATPase subunit:Short-chain dehydrogenases of various substrate specificities:Phosphoserine phosphatase:Glycerol uptake facilitator and related permeases (Major Intrinsic Protein Family):Multimeric flavodoxin WrbA:Carbonic anhydrases/acetyltransferases, isoleucine patch superfamily:Phosphoenolpyruvate-protein kinase (PTS system EI component in bacteria):Rubrerythrin:Phage shock protein A (IM30), suppresses sigma54-dependent transcription:Activator of 2-hydroxyglutaryl-CoA dehydratase (HSP70-class ATPase domain):Glycerol-3-phosphate responsive antiterminator (mRNA-binding):Galactose mutarotase and related enzymes:Uncharacterized conserved protein:Uncharacterized conserved protein:Uncharacterized protein conserved in bacteria:Beta-mannanase:Signal transduction histidine kinase:Leucine-rich repeat (LRR) protein:Amino acid transport and metabolism:Carbohydrate transport and metabolism:Lipid transport and metabolism:Transcription:Replication, recombination and repair:General function prediction only:Function unknown:Signal transduction mechanisms:CoA_E_activ:MIP:PTS_I_fam:HAD-SF-IB:CxxC_CxxC_SSSS:Enzymes of unknown specificity:Unknown function:Unknown substrate:Transport and binding proteins:DNA interactions:Regulatory functions:Metabolism:Poorly characterized:Cellular processes and signaling:Information storage and processing" 5 "Chromatin structure and dynamics:Energy production and conversion:FAD synthase:Dihydrofolate reductase:Ribosomal protein L33:NAD-dependent DNA ligase (contains BRCT domain type II):Predicted GTPase:ATPase involved in DNA replication initiation:Mg2+ and Co2+ transporters:Exopolyphosphatase-related proteins:Collagenase and related proteases:Galactose-1-phosphate uridylyltransferase:Histone acetyltransferase:Predicted periplasmic solute-binding protein:DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog:SOS-response transcriptional repressors (RecA-mediated autopeptidases):Predicted exonuclease:Uncharacterized protein involved in plasmid maintenance:Coenzyme transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:Replication, recombination and repair:Posttranslational modification, protein turnover, chaperones:Inorganic ion transport and metabolism:General function prediction only:Signal transduction mechanisms:ribF:galT_1:small_GTP:TIGR00247:DnaA:dnlj:rpmG_bact:spore_sigH:DNA replication, recombination, and repair:DNA metabolism:Sugars:Energy metabolism:Hypothetical proteins:Riboflavin, FMN, and FAD:Information storage and processing:Cellular processes and signaling:Metabolism:Poorly characterized:General:Unknown function:Conserved:Biosynthesis of cofactors, prosthetic groups, and carriers:Sporulation and germination:Cellular processes:Ribosomal proteins: synthesis and modification:Protein synthesis" 6 "N-formylmethionyl-tRNA deformylase:Membrane protease subunits, stomatin/prohibitin homologs:Thiamine monophosphate synthase:ATPases with chaperone activity, ATP-binding subunit:Serine/threonine protein phosphatase:Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain:Membrane-fusion protein:NAD-dependent protein deacetylases, SIR2 family:ABC-type antimicrobial peptide transport system, ATPase component:Uncharacterized protein conserved in bacteria:Flagellar GTP-binding protein:Trehalose and maltose hydrolases (possible phosphorylases):Membrane protein implicated in regulation of membrane protease activity:Uncharacterized enzyme of thiazole biosynthesis:Dioxygenases related to 2-nitropropane dioxygenase:Predicted N-acetylglucosamine kinase:Carbohydrate transport and metabolism:Coenzyme transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:Cell wall/membrane/envelope biogenesis:Cell motility:Posttranslational modification, protein turnover, chaperones:General function prediction only:Function unknown:Signal transduction mechanisms:pept_deformyl:RND_mfp:enACPred_II:chaperone_ClpB:FlhF:Intracellular trafficking, secretion, and vesicular transport:Defense mechanisms:Chemotaxis and motility:Cellular processes:Unknown substrate:Transport and binding proteins:Protein modification and repair:Information storage and processing:Protein fate:Cellular processes and signaling:Metabolism:Poorly characterized:Protein folding and stabilization" 7 "Energy production and conversion:Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase:Transcriptional regulator:Multimeric flavodoxin WrbA:FOG: CheY-like receiver:Glycosyltransferases, probably involved in cell wall biogenesis:4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family:NADH:flavin oxidoreductases, Old Yellow Enzyme family:Methylase involved in ubiquinone/menaquinone biosynthesis:Predicted membrane protein:Polyketide synthase modules and related proteins:Membrane protein putatively involved in post-translational modification of the autoinducing quorum-sensing peptide:Alpha-tubulin suppressor and related RCC1 domain-containing proteins:Cell cycle control, cell division, chromosome partitioning:Amino acid transport and metabolism:Coenzyme transport and metabolism:Transcription:Cell wall/membrane/envelope biogenesis:Posttranslational modification, protein turnover, chaperones:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:Function unknown:Signal transduction mechanisms:Cytoskeleton:Information storage and processing:Poorly characterized:Metabolism:Cellular processes and signaling" 8 "Ammonia permease:DNA-directed RNA polymerase, alpha subunit/40 kD subunit:Preprotein translocase subunit SecF:Preprotein translocase subunit SecD:Glycosyltransferase:Phosphopantothenoylcysteine synthetase/decarboxylase:Na+-driven multidrug efflux pump:Arylsulfatase regulator (Fe-S oxidoreductase):ABC-type proline/glycine betaine transport systems, ATPase components:Predicted glycosyltransferases:Predicted oxidoreductases of the aldo/keto reductase family:ATP-utilizing enzymes of the PP-loop superfamily:Periplasmic glycine betaine/choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein):Membrane protein involved in the export of O-antigen and teichoic acid:Iron only hydrogenase large subunit, C-terminal domain:Amino acid transport and metabolism:Coenzyme transport and metabolism:Transcription:Cell wall/membrane/envelope biogenesis:Inorganic ion transport and metabolism:General function prediction only:TIGR00268:HDIG:coaBC_dfp:matE:amt:2A0604s01:proV:rpoA:FeFe_hydrog_A:rSAM_six_Cys:Intracellular trafficking, secretion, and vesicular transport:Defense mechanisms:Information storage and processing:Pantothenate and coenzyme A:Biosynthesis of cofactors, prosthetic groups, and carriers:Conserved:Hypothetical proteins:Other:Cations and iron carrying compounds:Amino acids, peptides and amines:Transport and binding proteins:Protein and peptide secretion and trafficking:Protein fate:DNA-dependent RNA polymerase:Transcription:Cellular processes and signaling:Metabolism:Poorly characterized" 9 "Energy production and conversion:Histidinol phosphatase and related phosphatases:Glutathione peroxidase:Small-conductance mechanosensitive channel:6-pyruvoyl-tetrahydropterin synthase:Nitroreductase:Mannose-1-phosphate guanylyltransferase:ABC-type multidrug transport system, ATPase and permease components:Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis/translation initiation factor 2B, gamma/epsilon subunits (eIF-2Bgamma/eIF-2Bepsilon):DNA repair photolyase:Transcriptional regulators:Sugar transferases involved in lipopolysaccharide synthesis:Lysophospholipase L1 and related esterases:Capsular polysaccharide biosynthesis protein:Predicted DNA-binding protein with the Helix-hairpin-helix motif:Amino acid transport and metabolism:Coenzyme transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:Replication, recombination and repair:Cell wall/membrane/envelope biogenesis:Posttranslational modification, protein turnover, chaperones:General function prediction only:GmhB_yaeD:6_pyr_pter_rel:rSAM_link_UDG:photo_TT_lyase:Defense mechanisms:Information storage and processing:Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides:Cell envelope:Poorly characterized:Unknown function:Sporulation and germination:Cellular processes:Enzymes of unknown specificity:Metabolism:Cellular processes and signaling" 10 "Energy production and conversion:Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase:Tyrosyl-tRNA synthetase:Glucose-6-phosphate isomerase:Acetyl-CoA acetyltransferase:6-phosphofructokinase:Phosphotransacetylase:Uncharacterized conserved protein:Dihydrodipicolinate synthase/N-acetylneuraminate lyase:Threonyl-tRNA synthetase:Uncharacterized protein conserved in bacteria:Glutamate racemase:Transcriptional regulators:Tartrate dehydratase beta subunit/Fumarate hydratase class I, C-terminal domain:Electron transfer flavoprotein, alpha subunit:Predicted SAM-dependent methyltransferase:DNA polymerase III, gamma/tau subunits:Predicted membrane protein:Amino acid transport and metabolism:Carbohydrate transport and metabolism:Lipid transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:Replication, recombination and repair:Cell wall/membrane/envelope biogenesis:General function prediction only:Function unknown:glut_race:DNA_YbaB_EbfC:tyrS:thrS:YbgI_SA1388:pta:dapA:ttdB_fumA_fumB:GAPDH-I:AcCoA-C-Actrans:dnaX_nterm:PFKA_ATP:Biosynthesis and degradation of murein sacculus and peptidoglycan:Cell envelope:Aspartate family:Amino acid biosynthesis:General:Unknown function:tRNA aminoacylation:Poorly characterized:DNA replication, recombination, and repair:DNA metabolism:Other:Fatty acid and phospholipid metabolism:Glycolysis/gluconeogenesis:Fermentation:Energy metabolism:Protein synthesis:Metabolism:Cellular processes and signaling:Information storage and processing" 11 "Energy production and conversion:Nucleoside diphosphate kinase:Mismatch repair ATPase (MutS family):Putative translation initiation inhibitor, yjgF family:Predicted enzyme with a TIM-barrel fold:Molecular chaperone, HSP90 family:6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase:Uncharacterized flavoproteins:Cell division protein FtsI/penicillin-binding protein 2:Actin-like ATPase involved in cell division:Membrane protein TerC, possibly involved in tellurium resistance:Predicted phosphohydrolases:Transcriptional regulators:Transcriptional regulator/sugar kinase:Predicted transcriptional regulator:Uncharacterized protein conserved in bacteria:Predicted acetyltransferase:Cell cycle control, cell division, chromosome partitioning:Nucleotide transport and metabolism:Carbohydrate transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:Replication, recombination and repair:Cell wall/membrane/envelope biogenesis:Posttranslational modification, protein turnover, chaperones:Inorganic ion transport and metabolism:General function prediction only:Function unknown:TIGR00004:TIGR00044:TIGR00242:nagB:rrf2_super:ROK_glcA_fam:spoVD_pbp:R_switched_YjbE:Transcription:Amino sugars:Central intermediary metabolism:Cellular processes:Metabolism:Cellular processes and signaling:Information storage and processing:General:Enzymes of unknown specificity:Unknown function:Sporulation and germination:Poorly characterized:Degradation of RNA" 12 "Tryptophan synthase beta chain:Indole-3-glycerol phosphate synthase:Phosphoribosylanthranilate isomerase:Anthranilate/para-aminobenzoate synthases component I:Tryptophan synthase alpha chain:Anthranilate/para-aminobenzoate synthases component II:Anthranilate phosphoribosyltransferase:Sugar (pentulose and hexulose) kinases:Fructose-1-phosphate kinase and related fructose-6-phosphate kinase (PfkB):Phosphotransferase system, fructose-specific IIC component:Transcriptional regulators of sugar metabolism:Phosphotransferase system mannitol/fructose-specific IIA domain (Ntr-type):L-fucose isomerase and related proteins:Glucoamylase and related glycosyl hydrolases:Amino acid transport and metabolism:Carbohydrate transport and metabolism:Coenzyme transport and metabolism:Transcription:Signal transduction mechanisms:trpA:trpB:trpE_most:trpG_papA:FRU:fruA:trpD:XylB:1-PFK:Energy metabolism:Cellular processes and signaling:Metabolism:Information storage and processing:PTS:Signal transduction:Aromatic amino acid family:Amino acid biosynthesis:Sugars" 13 "Energy production and conversion:Biotin-(acetyl-CoA carboxylase) ligase:Glycosyltransferase:Superfamily II DNA and RNA helicases:Phosphatidylglycerophosphate synthase:Signal transduction histidine kinase:Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain:Tartrate dehydratase alpha subunit/Fumarate hydratase class I, N-terminal domain:Predicted membrane protein:Precorrin-6x reductase:Predicted membrane protein:Uncharacterized protein conserved in bacteria:Putative primosome component and related proteins:Protein involved in propanediol utilization, and related proteins (includes coumermycin biosynthetic protein), possible kinase:Coenzyme transport and metabolism:Lipid transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:Replication, recombination and repair:Cell wall/membrane/envelope biogenesis:Secondary metabolites biosynthesis, transport and catabolism:Function unknown:Signal transduction mechanisms:birA_ligase:pgsA:precor6x_red:ttdA_fumA_fumB:DnaD_dom:Heme, porphyrin, and cobalamin:Biosynthesis of cofactors, prosthetic groups, and carriers:Prophage functions:Mobile and extrachromosomal element functions:Protein modification and repair:Protein fate:Biosynthesis:Fatty acid and phospholipid metabolism:Metabolism:Poorly characterized:Cellular processes and signaling:Information storage and processing" 14 "Energy production and conversion:Molecular chaperone:ATPases involved in chromosome partitioning:Translation initiation factor 2 (IF-2; GTPase):ABC-type antimicrobial peptide transport system, permease component:Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain:Predicted transcriptional regulators:ATP-dependent exoDNAse (exonuclease V) beta subunit (contains helicase and exonuclease domains):DNA-directed RNA polymerase specialized sigma subunit:Transcriptional regulator:Flagellar GTP-binding protein:Uncharacterized conserved protein:Uncharacterized conserved protein:Trehalose and maltose hydrolases (possible phosphorylases):Malate/L-lactate dehydrogenases:Predicted glycosyltransferase:Cell cycle control, cell division, chromosome partitioning:Carbohydrate transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:Replication, recombination and repair:Cell wall/membrane/envelope biogenesis:Cell motility:Posttranslational modification, protein turnover, chaperones:Function unknown:Signal transduction mechanisms:small_GTP:TIGR00726:FliA_WhiG:addA_Gpos:FlhF:Defense mechanisms:General:Unknown function:Chemotaxis and motility:Poorly characterized:DNA replication, recombination, and repair:DNA metabolism:Cellular processes:Metabolism:Cellular processes and signaling:Information storage and processing" 15 "Energy production and conversion:ATP phosphoribosyltransferase:Phosphoribosylformimino-5-aminoimidazole carboxamide ribonucleotide (ProFAR) isomerase:Imidazoleglycerol-phosphate synthase:Glutamine amidotransferase:Phosphoribosyl-AMP cyclohydrolase:Phosphoribosyl-ATP pyrophosphohydrolase:Histidinol dehydrogenase:Membrane protease subunits, stomatin/prohibitin homologs:Uncharacterized membrane protein:Ferredoxin:Uncharacterized conserved protein, contains double-stranded beta-helix domain:Predicted sugar phosphate isomerase:Deoxycytidylate deaminase:Uncharacterized membrane protein, required for spore maturation in B.subtilis.:Uncharacterized protein conserved in bacteria:ATP phosphoribosyltransferase involved in histidine biosynthesis:Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IIC:Amino acid transport and metabolism:Nucleotide transport and metabolism:Carbohydrate transport and metabolism:Posttranslational modification, protein turnover, chaperones:General function prediction only:Function unknown:TIGR00007:hisD:hisG:TIGR00274:hisZ_biosyn_reg:hisF:IMP_synth_hisH:histidine_hisI:Metabolism:Poorly characterized:Cellular processes and signaling:Biosynthesis and degradation of murein sacculus and peptidoglycan:Cell envelope:Histidine family:Amino acid biosynthesis" 16 "" 17 "Transketolase:Transaldolase:Cation transport ATPase:Predicted Fe-S oxidoreductases:Galactose mutarotase and related enzymes:Uncharacterized protein conserved in bacteria:Carbohydrate transport and metabolism:Inorganic ion transport and metabolism:General function prediction only:Function unknown:tktlase_bact:fsa_talC_mipB:ATPase_P-type:spore_III_AG:spore_III_AB:spore_III_AC:spore_III_AD:spore_III_AA:spore_III_AF:Energy metabolism:Cellular processes:Poorly characterized:Metabolism:Sporulation and germination:Pentose phosphate pathway" 18 "Energy production and conversion:Glucan phosphorylase:Single-stranded DNA-binding protein:Fe-S oxidoreductase:Acetyltransferases, including N-acetylases of ribosomal proteins:Putative peptidoglycan-binding domain-containing protein:Predicted integral membrane protein:Carbohydrate transport and metabolism:Translation, ribosomal structure and biogenesis:Replication, recombination and repair:Cell wall/membrane/envelope biogenesis:Function unknown:P_ylase:6_pyr_pter_rel:Metabolism:Cellular processes and signaling:Information storage and processing:Biosynthesis and degradation of polysaccharides:Energy metabolism:Poorly characterized" 19 "Energy production and conversion:Glycosyltransferase:Translation elongation factors (GTPases):ATPase components of ABC transporters with duplicated ATPase domains:rRNA methylases:UDP-N-acetyl-D-mannosaminuronate dehydrogenase:Chemotaxis signal transduction protein:ABC-type multidrug transport system, ATPase component:Predicted alternative thymidylate synthase:Fructose-1,6-bisphosphatase/sedoheptulose 1,7-bisphosphatase and related proteins:L-serine deaminase:3-methyladenine DNA glycosylase:Signal transduction histidine kinase regulating citrate/malate metabolism:Predicted double-stranded RNA/RNA-DNA hybrid binding protein:Predicted RNA-binding protein containing a PIN domain:ABC-type Na+ transport system, ATPase component:Exopolysaccharide biosynthesis protein related to N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase:Amino acid transport and metabolism:Nucleotide transport and metabolism:Carbohydrate transport and metabolism:Translation, ribosomal structure and biogenesis:Replication, recombination and repair:Cell wall/membrane/envelope biogenesis:Cell motility:Inorganic ion transport and metabolism:General function prediction only:Signal transduction mechanisms:rRNA_methyl_3:small_GTP:glpX:3mg:sda_alpha:GPR:NDP-sugDHase:Defense mechanisms:Sporulation and germination:Cellular processes:tRNA and rRNA base modification:Protein synthesis:Poorly characterized:DNA metabolism:Pentose phosphate pathway:Glycolysis/gluconeogenesis:Energy metabolism:DNA replication, recombination, and repair:Metabolism:Cellular processes and signaling:Information storage and processing:General:Unknown function" 20 "Energy production and conversion:Xaa-Pro aminopeptidase:Glutamyl- and glutaminyl-tRNA synthetases:Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase:Ribosomal protein S9:Glycine/serine hydroxymethyltransferase:Ribosomal protein L17:Cell division GTPase:3-oxoacyl-[acyl-carrier-protein] synthase III:Amino acid transporters:Phosphoserine phosphatase:Phosphoglyceromutase:Methyl-accepting chemotaxis protein:dTDP-D-glucose 4,6-dehydratase:6Fe-6S prismane cluster-containing protein:Transcription termination factor:Uncharacterized protein conserved in bacteria:Transcriptional regulators of sugar metabolism:Adenylate cyclase, class 2 (thermophilic):Transcriptional regulators:Transcriptional regulator, contains sigma factor-related N-terminal domain:Exopolysaccharide biosynthesis protein related to N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase:Spore coat protein:Cell cycle control, cell division, chromosome partitioning:Amino acid transport and metabolism:Nucleotide transport and metabolism:Carbohydrate transport and metabolism:Lipid transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:Cell wall/membrane/envelope biogenesis:Cell motility:Function unknown:Signal transduction mechanisms:L17:ftsZ:gltX_bact:fabH:DegV:rho:dTDP_gluc_dehyt:pgm_bpd_ind:HAD-SF-IB:GAPDH-I:CO_DH_cata:Transcription:Biosynthesis:Fatty acid and phospholipid metabolism:Glycolysis/gluconeogenesis:Energy metabolism:tRNA aminoacylation:Metabolism:Cellular processes and signaling:Information storage and processing:Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides:Cell envelope:General:Enzymes of unknown specificity:Unknown function:Cell division:Cellular processes:Ribosomal proteins: synthesis and modification:Poorly characterized:Protein synthesis:Transcription factors" 21 "Lyzozyme M1 (1,4-beta-N-acetylmuramidase):Phage-related protein:Phage-related protein:Phage-related protein:Bacterial surface proteins containing Ig-like domains:Cell wall/membrane/envelope biogenesis:Cell motility:Function unknown:phi3626_gp14_N:put_anti_recept:Mobile and extrachromosomal element functions:Cellular processes and signaling:Poorly characterized:Prophage functions" 22 "Energy production and conversion:Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases:Single-stranded DNA-specific exonuclease:Predicted Zn-dependent peptidases:ABC-type dipeptide transport system, periplasmic component:Threonine dehydrogenase and related Zn-dependent dehydrogenases:Cellulase M and related proteins:Malate/L-lactate dehydrogenases:K+-transporting ATPase, A chain:K+-transporting ATPase, c chain:L-arabinose isomerase:Osmosensitive K+ channel histidine kinase:High-affinity K+ transport system, ATPase chain B:Phosphoketolase:Leucine-rich repeat (LRR) protein:Endopolygalacturonase:Bacterial surface proteins containing Ig-like domains:Amino acid transport and metabolism:Carbohydrate transport and metabolism:Replication, recombination and repair:Cell wall/membrane/envelope biogenesis:Cell motility:Inorganic ion transport and metabolism:General function prediction only:Function unknown:Signal transduction mechanisms:recJ:kdpA:kdpC:araD:ATPase_P-type:spore_V_AE:spore_V_AD:spore_yqfC:spore_yqfD:DNA replication, recombination, and repair:DNA metabolism:Sugars:Energy metabolism:Information storage and processing:Poorly characterized:Cellular processes and signaling:Metabolism:Sporulation and germination:Cellular processes:Cations and iron carrying compounds:Transport and binding proteins" 23 "Energy production and conversion:Cysteine synthase:3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase and related enzymes:SAM-dependent methyltransferases:Adenylylsulfate kinase and related kinases:ABC-type nitrate/sulfonate/bicarbonate transport system, permease component:Cystathionine beta-lyases/cystathionine gamma-synthases:ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components:Flavodoxins:ABC-type amino acid transport system, permease component:ABC-type amino acid transport/signal transduction systems, periplasmic component/domain:Succinate dehydrogenase/fumarate reductase, flavoprotein subunit:Hydrolases of the alpha/beta superfamily:ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component:ABC-type polar amino acid transport system, ATPase component:Ferredoxin:O-acetylhomoserine sulfhydrylase:GTPases - Sulfate adenylate transferase subunit 1:Uncharacterized small protein:Amino acid transport and metabolism:Coenzyme transport and metabolism:Inorganic ion transport and metabolism:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:Function unknown:Signal transduction mechanisms:small_GTP:apsK:cysKM:HEQRo_perm_3TM:SsuA_fam:Amino acid biosynthesis:General:Unknown function:Other:Amino acids, peptides and amines:Transport and binding proteins:Sulfur metabolism:Central intermediary metabolism:Metabolism:Poorly characterized:Cellular processes and signaling:Serine family" 24 "Energy production and conversion:Multimeric flavodoxin WrbA:Flavodoxins:Alanine racemase:Methyl-accepting chemotaxis protein:ABC-type multidrug transport system, permease component:Metal-dependent amidase/aminoacylase/carboxypeptidase:Predicted transcriptional regulators:ABC-type sugar transport system, periplasmic component:Mn2+ and Fe2+ transporters of the NRAMP family:ATPase related to the helicase subunit of the Holliday junction resolvase:Lysophospholipase:Regulator of cell morphogenesis and NO signaling:Predicted integral membrane protein:Cell cycle control, cell division, chromosome partitioning:Carbohydrate transport and metabolism:Lipid transport and metabolism:Transcription:Replication, recombination and repair:Cell wall/membrane/envelope biogenesis:Cell motility:Inorganic ion transport and metabolism:General function prediction only:Function unknown:Signal transduction mechanisms:alr:2A0309:amidohydrolases:spore_II_R:spore_ger_x_C:6_pyr_pter_rel:FeS_repair_RIC:Defense mechanisms:Biosynthesis and degradation of murein sacculus and peptidoglycan:Biosynthesis of cofactors, prosthetic groups, and carriers:Sporulation and germination:Cellular processes:Amino acids, peptides and amines:Transport and binding proteins:Degradation of proteins, peptides, and glycopeptides:Protein fate:Cell envelope:Other:Poorly characterized:Metabolism:Cellular processes and signaling:Information storage and processing" 25 "Energy production and conversion:Ribosomal protein L7/L12:Holliday junction resolvasome, DNA-binding subunit:Uncharacterized membrane protein (homolog of Drosophila rhomboid):Flavodoxins:Fe2+/Zn2+ uptake regulation proteins:Preprotein translocase subunit SecG:Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase:Uncharacterized protein conserved in bacteria:Predicted transcriptional regulator:Sugar transferases involved in lipopolysaccharide synthesis:Uncharacterized protein conserved in bacteria:Superfamily II DNA/RNA helicase required for DNA uptake (late competence protein):Lipid transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:Replication, recombination and repair:Cell wall/membrane/envelope biogenesis:Inorganic ion transport and metabolism:General function prediction only:Function unknown:ruvA:TIGR00147:rrf2_super:secG:EPS_sugtrans:Intracellular trafficking, secretion, and vesicular transport:DNA replication, recombination, and repair:DNA metabolism:Enzymes of unknown specificity:Metabolism:Cellular processes and signaling:Information storage and processing:General:Poorly characterized:Unknown function:Protein and peptide secretion and trafficking:Protein fate" 26 "Energy production and conversion:Aspartate-semialdehyde dehydrogenase:Polyferredoxin:Carbamoylphosphate synthase large subunit (split gene in MJ):Pseudouridylate synthases, 23S RNA-specific:Uncharacterized membrane-associated protein:Chemotaxis signal transduction protein:Recombinational DNA repair ATPase (RecF pathway):dTDP-glucose pyrophosphorylase:Serine kinase of the HPr protein, regulates carbohydrate metabolism:Ketopantoate reductase:Site-specific recombinases, DNA invertase Pin homologs:Holliday junction resolvasome, helicase subunit:Permeases of the major facilitator superfamily:Dipeptide/tripeptide permease:Uncharacterized protein containing a NRPS condensation (elongation) domain:Amino acid transport and metabolism:Nucleotide transport and metabolism:Coenzyme transport and metabolism:Translation, ribosomal structure and biogenesis:Replication, recombination and repair:Cell wall/membrane/envelope biogenesis:Cell motility:General function prediction only:Function unknown:Signal transduction mechanisms:rluA_subfam:recf:ruvB:efflux_EmrB:apbA_panE:2A0309:asd_EA:rmlA:Cellular processes and signaling:Information storage and processing:Amino acid biosynthesis:Other:Amino acids, peptides and amines:Transport and binding proteins:tRNA and rRNA base modification:Protein synthesis:DNA replication, recombination, and repair:DNA metabolism:Poorly characterized:Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides:Metabolism:Cell envelope:Pantothenate and coenzyme A:Biosynthesis of cofactors, prosthetic groups, and carriers:Aspartate family" 27 "Cysteine synthase:Sulfite reductase, beta subunit (hemoprotein):Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis:Esterase/lipase:Permeases of the drug/metabolite transporter (DMT) superfamily:ABC-type multidrug transport system, ATPase component:Uncharacterized conserved protein:Transcriptional regulator:Predicted HD superfamily hydrolase:ABC-type metal ion transport system, periplasmic component/surface antigen:Transcriptional regulators:Predicted membrane protein:Predicted Zn peptidase:O-acetylhomoserine sulfhydrylase:Predicted oxidoreductase related to nitroreductase:Predicted membrane protein:Amino acid transport and metabolism:Carbohydrate transport and metabolism:Lipid transport and metabolism:Transcription:Cell wall/membrane/envelope biogenesis:Inorganic ion transport and metabolism:General function prediction only:Function unknown:cysKM:OAH_OAS_sulfhy:Defense mechanisms:Metabolism:Cellular processes and signaling:Poorly characterized:Serine family:Amino acid biosynthesis:Information storage and processing" 28 "Energy production and conversion:Uracil phosphoribosyltransferase:Superfamily II DNA/RNA helicases, SNF2 family:Chemotaxis signal transduction protein:Fe-S oxidoreductase:ABC-type cobalt transport system, ATPase component:ABC-type antimicrobial peptide transport system, ATPase component:Phosphatidylserine synthase:Predicted glycosyltransferases:Phosphotransferase system cellobiose-specific component IIA:Alcohol dehydrogenase, class IV:Fructose-1,6-bisphosphatase/sedoheptulose 1,7-bisphosphatase and related proteins:DNA polymerase III, alpha subunit (gram-positive type):SAM-dependent methyltransferases related to tRNA (uracil-5-)-methyltransferase:Lysophospholipase:Uncharacterized protein conserved in bacteria:Uncharacterized conserved protein:Transcriptional regulator, effector-binding domain/component:Nucleotide transport and metabolism:Carbohydrate transport and metabolism:Lipid transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:Replication, recombination and repair:Cell motility:Inorganic ion transport and metabolism:General function prediction only:Function unknown:Signal transduction mechanisms:CoA_E_activ:glpX:rumA:dnaq:upp:Defense mechanisms:tRNA and rRNA base modification:Protein synthesis:Degradation of DNA:DNA metabolism:Poorly characterized:Purines, pyrimidines, nucleosides, and nucleotides:Pentose phosphate pathway:Energy metabolism:Salvage of nucleosides and nucleotides:Metabolism:Cellular processes and signaling:Information storage and processing" 29 "Energy production and conversion:Predicted sugar kinase:Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), A subunit:Integral membrane protein possibly involved in chromosome condensation:Glycosyltransferase:Acetolactate synthase, small (regulatory) subunit:NADPH-dependent glutamate synthase beta chain and related oxidoreductases:Signal recognition particle GTPase:ABC-type dipeptide/oligopeptide/nickel transport systems, permease components:2-methylthioadenine synthetase:Signal transduction histidine kinase:Phosphopantetheinyl transferase (holo-ACP synthase):Cell division protein FtsI/penicillin-binding protein 2:Nitroreductase:Actin-like ATPase involved in cell division:Pyruvate carboxylase:ABC-type dipeptide/oligopeptide/nickel transport systems, permease components:Predicted membrane protein, hemolysin III homolog:Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor):DNA segregation ATPase FtsK/SpoIIIE and related proteins:Predicted transcriptional regulators:Uncharacterized protein conserved in bacteria:Copper chaperone:Uncharacterized conserved protein, possibly involved in methylthioadenosine recycling:Bacterial surface proteins containing Ig-like domains:Cell cycle control, cell division, chromosome partitioning:Amino acid transport and metabolism:Carbohydrate transport and metabolism:Lipid transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:Replication, recombination and repair:Cell wall/membrane/envelope biogenesis:Cell motility:Inorganic ion transport and metabolism:General function prediction only:Function unknown:Signal transduction mechanisms:ftsY:TIGR00089:acolac_sm:yjeF_cterm:ant_ant_sig:crcB:acpS:gyrA:hlyIII:ftsA:pyruv_carbox:GOGAT_sm_gam:HAD-SF-IB:spoVD_pbp:Intracellular trafficking, secretion, and vesicular transport:Biosynthesis:Information storage and processing:Cellular processes and signaling:Metabolism:Poorly characterized:Amino acid biosynthesis:General:Enzymes of unknown specificity:Unknown function:Sporulation and germination:Cell division:Cellular processes:Protein and peptide secretion and trafficking:Protein fate:DNA replication, recombination, and repair:DNA metabolism:Protein interactions:Regulatory functions:Pyruvate family:Fatty acid and phospholipid metabolism:Glycolysis/gluconeogenesis:Energy metabolism" 30 "Energy production and conversion:Predicted epimerase, PhzC/PhzF homolog:Cation transport ATPase:Thiol-disulfide isomerase and thioredoxins:2-polyprenylphenol hydroxylase and related flavodoxin oxidoreductases:Glycerol uptake facilitator and related permeases (Major Intrinsic Protein Family):Cytosine/adenosine deaminases:Predicted PP-loop superfamily ATPase:Predicted DNA-binding proteins:Activator of 2-hydroxyglutaryl-CoA dehydratase (HSP70-class ATPase domain):Predicted membrane protein:Predicted acetyltransferase:Uncharacterized protein conserved in bacteria:Uncharacterized protein conserved in bacteria:Nucleotide transport and metabolism:Carbohydrate transport and metabolism:Coenzyme transport and metabolism:Lipid transport and metabolism:Translation, ribosomal structure and biogenesis:Posttranslational modification, protein turnover, chaperones:Inorganic ion transport and metabolism:General function prediction only:Function unknown:CoA_E_activ:TIGR00364:PhzF_family:thioredoxin:Information storage and processing:General:Unknown function:Toxin production and resistance:Cellular processes:Electron transport:Energy metabolism:Metabolism:Poorly characterized:Cellular processes and signaling" 31 "Energy production and conversion:Predicted amidohydrolase:ATP-dependent Lon protease, bacterial type:Thioredoxin reductase:Permeases of the drug/metabolite transporter (DMT) superfamily:ABC-type transport system involved in Fe-S cluster assembly, permease component:Nicotinic acid mononucleotide adenylyltransferase:Uncharacterized conserved protein:Predicted transcriptional regulators:Rubredoxin:Predicted transcriptional regulator:Putative stress-responsive transcriptional regulator:Regulators of stationary/sporulation gene expression:Uncharacterized conserved protein:Phosphosulfolactate phosphohydrolase and related enzymes:Dioxygenases related to 2-nitropropane dioxygenase:Predicted glutamine amidotransferases:Sugar transferases involved in lipopolysaccharide synthesis:Predicted Zn peptidase:Amino acid transport and metabolism:Carbohydrate transport and metabolism:Coenzyme transport and metabolism:Transcription:Cell wall/membrane/envelope biogenesis:Posttranslational modification, protein turnover, chaperones:General function prediction only:Function unknown:Signal transduction mechanisms:cyt_tran_rel:TIGR00266:nadE:rrf2_super:lon:TRX_reduct:lp_hng_hel_AbrB:sufB:EPS_sugtrans:Unknown function:Conserved:Hypothetical proteins:Degradation of proteins, peptides, and glycopeptides:Protein fate:DNA interactions:Regulatory functions:Electron transport:Energy metabolism:Metabolism:Poorly characterized:Cellular processes and signaling:Information storage and processing:Pyridine nucleotides:Other:Biosynthesis of cofactors, prosthetic groups, and carriers:General" 32 "Fructose/tagatose bisphosphate aldolase:S-adenosylmethionine synthetase:Ribosomal protein L27:Acyl carrier protein:Ribosomal protein S18:Translation initiation factor 3 (IF-3):Ribosomal protein L35:Ribosomal protein L20:Ribosomal protein L32:Ribosomal protein L19:Recombinational DNA repair protein (RecF pathway):Ribosomal protein S6:Single-stranded DNA-binding protein:Bacterial nucleoid DNA-binding protein:Acetyl-CoA carboxylase alpha subunit:Cold shock proteins:Uncharacterized conserved protein:Growth inhibitor:Predicted ribosomal protein:Carbohydrate transport and metabolism:Coenzyme transport and metabolism:Lipid transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:Replication, recombination and repair:Secondary metabolites biosynthesis, transport and catabolism:Function unknown:Signal transduction mechanisms:rpmI_bact:L27:S18:S6:cbbA:infC:accA:acyl_carrier:recR:ssb:rplS_bact:rpmF_bact:rplT_bact:metK:Protein synthesis:DNA replication, recombination, and repair:DNA metabolism:Biosynthesis:Poorly characterized:Glycolysis/gluconeogenesis:Energy metabolism:Other:Central intermediary metabolism:Fatty acid and phospholipid metabolism:Metabolism:Cellular processes and signaling:Information storage and processing:Translation factors:Ribosomal proteins: synthesis and modification" 33 "Energy production and conversion:Malate/lactate dehydrogenases:Zn-dependent hydrolases, including glyoxylases:ABC-type Fe3+-siderophore transport system, permease component:ABC-type Fe3+-hydroxamate transport system, periplasmic component:ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components:Transcriptional regulators:Cation transport ATPase:Predicted membrane protein:ABC-type transport system, involved in lipoprotein release, permease component:Coenzyme transport and metabolism:Transcription:Cell wall/membrane/envelope biogenesis:Inorganic ion transport and metabolism:General function prediction only:Function unknown:ATPase_P-type:L-LDH-NAD:Metabolism:Cellular processes and signaling:Information storage and processing:Glycolysis/gluconeogenesis:Energy metabolism:Poorly characterized" 34 "Energy production and conversion:Gamma-glutamyl phosphate reductase:Dihydropteroate synthase and related enzymes:Aspartate/tyrosine/aromatic aminotransferase:Adenine/guanine phosphoribosyltransferases and related PRPP-binding proteins:Endonuclease IV:Phosphatidylserine decarboxylase:Cell division protein FtsI/penicillin-binding protein 2:Membrane protein TerC, possibly involved in tellurium resistance:Na+/H+-dicarboxylate symporters:Uncharacterized conserved protein:Tetrahydrodipicolinate N-succinyltransferase:Uncharacterized proteins involved in stress response, homologs of TerZ and putative cAMP-binding protein CABP1:Uncharacterized conserved protein:Predicted N-acetylglucosaminyl transferase:Uncharacterized protein conserved in bacteria:Amino acid transport and metabolism:Nucleotide transport and metabolism:Carbohydrate transport and metabolism:Coenzyme transport and metabolism:Lipid transport and metabolism:Replication, recombination and repair:Cell wall/membrane/envelope biogenesis:Inorganic ion transport and metabolism:Function unknown:Signal transduction mechanisms:PS_decarb:proA:DHPS:XPRTase:yecD_yerC:DapD_Ac:R_switched_YkoY:Glutamate family:Amino acid biosynthesis:General:Unknown function:Salvage of nucleosides and nucleotides:Purines, pyrimidines, nucleosides, and nucleotides:Biosynthesis:Fatty acid and phospholipid metabolism:Information storage and processing:Poorly characterized:Folic acid:Cellular processes and signaling:Metabolism:Biosynthesis of cofactors, prosthetic groups, and carriers" 35 "Predicted GTPase, probable translation factor:Phenylalanyl-tRNA synthetase alpha subunit:Predicted sugar kinase:Phenylalanyl-tRNA synthetase beta subunit:L-asparaginase/archaeal Glu-tRNAGln amidotransferase subunit D:NAD-dependent DNA ligase (contains BRCT domain type II):Cytidylate kinase:Nuclease subunit of the excinuclease complex:Protein-tyrosine-phosphatase:ATPase involved in DNA repair:GMP synthase, PP-ATPase domain/subunit:2-methylthioadenine synthetase:cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases:S-adenosylmethionine:tRNA-ribosyltransferase-isomerase (queuine synthetase):Actin-like ATPase involved in cell morphogenesis:Predicted rRNA methylase:Arginine repressor:Exonuclease VII, large subunit:GTPases:Permeases of the major facilitator superfamily:Cell cycle control, cell division, chromosome partitioning:Amino acid transport and metabolism:Nucleotide transport and metabolism:Carbohydrate transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:Replication, recombination and repair:General function prediction only:Signal transduction mechanisms:cmk:TIGR00089:TIGR00092:queA:uvrC:xseA:pheS:pheT_bact:tly:dnlj:recN:guaA_Cterm:mreB:argR_whole:GTP_HflX:shape_MreD:Unknown function:tRNA and rRNA base modification:tRNA aminoacylation:Protein synthesis:DNA replication, recombination, and repair:Degradation of DNA:Poorly characterized:DNA interactions:Regulatory functions:Purine ribonucleotide biosynthesis:Nucleotide and nucleoside interconversions:Purines, pyrimidines, nucleosides, and nucleotides:DNA metabolism:Metabolism:Cellular processes and signaling:Information storage and processing:Biosynthesis and degradation of murein sacculus and peptidoglycan:Cell envelope:General" 36 "Energy production and conversion:DNA mismatch repair enzyme (predicted ATPase):Glucosamine 6-phosphate synthetase, contains amidotransferase and phosphosugar isomerase domains:Translation elongation factors (GTPases):ATPases involved in chromosome partitioning:2-methylthioadenine synthetase:Putative intracellular protease/amidase:Ribose 5-phosphate isomerase RpiB:Predicted xylanase/chitin deacetylase:NifU homolog involved in Fe-S cluster formation:Membrane-fusion protein:Predicted ATP-dependent serine protease:Predicted ATP-dependent protease:Actin-like ATPase involved in cell morphogenesis:ABC-type multidrug transport system, ATPase component:ABC-type transport system involved in multi-copper enzyme maturation, permease component:Uncharacterized protein conserved in bacteria:Predicted kinase related to dihydroxyacetone kinase:Predicted nucleic-acid-binding protein (contains the HHH domain):Uncharacterized homolog of PSP1:Uncharacterized protein conserved in bacteria:Predicted membrane protein:Cell cycle control, cell division, chromosome partitioning:Carbohydrate transport and metabolism:Translation, ribosomal structure and biogenesis:Replication, recombination and repair:Cell wall/membrane/envelope biogenesis:Posttranslational modification, protein turnover, chaperones:General function prediction only:Function unknown:TIGR00089:small_GTP:sms:mutl:rpiB_lacA_lacB:mreB:eps_fam:glmS:not_thiJ:spore_lon_C:YloV:T7_EssB:T7_EssCb_Firm:Defense mechanisms:Transport and binding proteins:Biosynthesis and degradation of murein sacculus and peptidoglycan:Information storage and processing:Cellular processes and signaling:Metabolism:Poorly characterized:General:Unknown function:Sporulation and germination:Cellular processes:Carbohydrates, organic alcohols, and acids:Cell envelope:Protein and peptide secretion and trafficking:Protein fate:DNA replication, recombination, and repair:DNA metabolism:Amino sugars:Central intermediary metabolism" 37 "Energy production and conversion:Aspartyl/asparaginyl-tRNA synthetases:Cysteine synthase:Asp-tRNAAsn/Glu-tRNAGln amidotransferase B subunit (PET112 homolog):3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase and related enzymes:SAM-dependent methyltransferases:Adenylylsulfate kinase and related kinases:ABC-type nitrate/sulfonate/bicarbonate transport system, permease component:Cystathionine beta-lyases/cystathionine gamma-synthases:ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components:ABC-type amino acid transport system, permease component:ABC-type amino acid transport/signal transduction systems, periplasmic component/domain:Succinate dehydrogenase/fumarate reductase, flavoprotein subunit:ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component:ABC-type polar amino acid transport system, ATPase component:Ferredoxin:O-acetylhomoserine sulfhydrylase:GTPases - Sulfate adenylate transferase subunit 1:Amino acid transport and metabolism:Coenzyme transport and metabolism:Translation, ribosomal structure and biogenesis:Inorganic ion transport and metabolism:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:Signal transduction mechanisms:gatB:small_GTP:apsK:aspS_arch:cysKM:HEQRo_perm_3TM:SsuA_fam:General:Unknown function:Other:Amino acids, peptides and amines:Transport and binding proteins:tRNA aminoacylation:Protein synthesis:Sulfur metabolism:Central intermediary metabolism:Metabolism:Poorly characterized:Cellular processes and signaling:Information storage and processing:Serine family:Amino acid biosynthesis" 38 "Ribosomal protein L31:Aspartate/tyrosine/aromatic aminotransferase:cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases:Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains):Cell division protein FtsI/penicillin-binding protein 2:Predicted RNA binding protein (contains ribosomal protein S1 domain):Predicted membrane protein, hemolysin III homolog:Predicted transcriptional regulators:Uncharacterized protein conserved in bacteria:Regulator of competence-specific genes:Predicted HD-superfamily hydrolase:Response regulator with putative antiterminator output domain:Predicted membrane protein:Signal transduction histidine kinase:Amino acid transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:Cell wall/membrane/envelope biogenesis:General function prediction only:Function unknown:Signal transduction mechanisms:L31:hlyIII:Metabolism:Cellular processes and signaling:Information storage and processing:Ribosomal proteins: synthesis and modification:Protein synthesis:Poorly characterized" 39 "Glycosyltransferase:Predicted ATPase with chaperone activity:Signal transduction histidine kinase:Uncharacterized membrane protein:Predicted Rossmann fold nucleotide-binding protein involved in DNA uptake:ABC-type proline/glycine betaine transport systems, permease component:DNA-directed RNA polymerase specialized sigma subunit:Amidases related to nicotinamidase:Predicted membrane protein:Uncharacterized conserved protein:Predicted aminopeptidases:Protein involved in polysaccharide intercellular adhesin (PIA) synthesis/biofilm formation:Amino acid transport and metabolism:Carbohydrate transport and metabolism:Transcription:Replication, recombination and repair:Cell wall/membrane/envelope biogenesis:Posttranslational modification, protein turnover, chaperones:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:Function unknown:Signal transduction mechanisms:TIGR00368:dprA:spo_yunB:spore_sigmaK:spore_II_P:pip_yhgE_Nterm:Intracellular trafficking, secretion, and vesicular transport:Unknown function:Sporulation and germination:DNA transformation:Cellular processes:General:Information storage and processing:Cellular processes and signaling:Metabolism:Poorly characterized" 40 "Thiamine biosynthesis ATP pyrophosphatase:Zn-dependent protease with chaperone function:Amino acid transporters:Na+-driven multidrug efflux pump:Transcriptional regulator:ABC-type nitrate/sulfonate/bicarbonate transport system, permease component:Cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes:Phosphomannomutase:Gamma-aminobutyrate permease and related permeases:Predicted RNA-binding protein homologous to eukaryotic snRNP:Putative effector of murein hydrolase:Putative effector of murein hydrolase LrgA:Uracil-DNA glycosylase:Predicted redox protein, regulator of disulfide bond formation:Adenosine deaminase:Mn2+ and Fe2+ transporters of the NRAMP family:Amino acid transport and metabolism:Nucleotide transport and metabolism:Carbohydrate transport and metabolism:Coenzyme transport and metabolism:Transcription:Replication, recombination and repair:Cell wall/membrane/envelope biogenesis:Posttranslational modification, protein turnover, chaperones:Inorganic ion transport and metabolism:General function prediction only:TIGR00342:matE:aden_deam:glmM:Defense mechanisms:Information storage and processing:Other:Transport and binding proteins:Poorly characterized:Protein synthesis:Amino sugars:Central intermediary metabolism:tRNA and rRNA base modification:Metabolism:Cellular processes and signaling" 41 "Energy production and conversion:FAD/FMN-containing dehydrogenases:Predicted amidohydrolase:Uncharacterized conserved protein:Molecular chaperone:ATPases involved in chromosome partitioning:Selenocysteine lyase:ATPases with chaperone activity, ATP-binding subunit:DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32):Signal transduction histidine kinase:Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, beta subunit:Predicted ATP-dependent protease:ABC-type proline/glycine betaine transport systems, ATPase components:DNA-directed RNA polymerase specialized sigma subunit:Uncharacterized membrane protein:Uncharacterized protein conserved in bacteria:Periplasmic glycine betaine/choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein):Transcriptional regulators:Electron transfer flavoprotein, alpha subunit:Electron transfer flavoprotein, beta subunit:Predicted glycosyltransferase:Cell cycle control, cell division, chromosome partitioning:Amino acid transport and metabolism:Transcription:Cell wall/membrane/envelope biogenesis:Posttranslational modification, protein turnover, chaperones:General function prediction only:Function unknown:Signal transduction mechanisms:MG103:CofD_related:am_tr_V_EF2568:PorB_KorB:FliA_WhiG:spore_lonB:sigma70-ECF:chaperone_ClpB:Hypothetical proteins:Sporulation and germination:Cellular processes:Protein folding and stabilization:Protein fate:Metabolism:Poorly characterized:Cellular processes and signaling:Information storage and processing:Enzymes of unknown specificity:Unknown function:Conserved" 42 "Energy production and conversion:Glycogen synthase:ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component:ADP-glucose pyrophosphorylase:ABC-type dipeptide/oligopeptide/nickel transport systems, permease components:Phosphopantetheinyl transferase (holo-ACP synthase):5'-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases:ABC-type dipeptide/oligopeptide/nickel transport systems, permease components:NADH:flavin oxidoreductases, Old Yellow Enzyme family:Serine phosphatase RsbU, regulator of sigma subunit:ABC-type oligopeptide transport system, periplasmic component:ABC-type oligopeptide transport system, ATPase component:Amino acid transport and metabolism:Nucleotide transport and metabolism:Carbohydrate transport and metabolism:Lipid transport and metabolism:Transcription:Inorganic ion transport and metabolism:Signal transduction mechanisms:acpS:LPXTG_anchor:oligo_HPY:glgC:glgD:glgA:spore_II_GA:spore_II_E:Amino acids, peptides and amines:Transport and binding proteins:Biosynthesis:Metabolism:Biosynthesis and degradation of polysaccharides:Energy metabolism:Fatty acid and phospholipid metabolism:Cellular processes and signaling:Information storage and processing:Other:Cell envelope:Sporulation and germination:Cellular processes" 43 "Sugar kinases, ribokinase family:ABC-type dipeptide/oligopeptide/nickel transport systems, permease components:Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific:Arabinose efflux permease:Uncharacterized protein conserved in bacteria:Ethanolamine ammonia-lyase, large subunit:NAD+--asparagine ADP-ribosyltransferase:Amino acid transport and metabolism:Carbohydrate transport and metabolism:Inorganic ion transport and metabolism:Function unknown:Signal transduction mechanisms:EIIB_glc:Cellular processes and signaling:PTS:Signal transduction:Poorly characterized:Metabolism" 44 "ATPase components of ABC transporters with duplicated ATPase domains:NADPH-dependent glutamate synthase beta chain and related oxidoreductases:Biotin carboxyl carrier protein:Signal transduction histidine kinase:Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain:UDP-N-acetylmuramoylalanine-D-glutamate ligase:Histidinol phosphatase and related hydrolases of the PHP family:Uncharacterized conserved protein:N-acetylglucosamine-6-phosphate deacetylase:Site-specific recombinases, DNA invertase Pin homologs:Predicted hydrolase (metallo-beta-lactamase superfamily):Uncharacterized protein conserved in bacteria:Predicted membrane protein:Acetyl/propionyl-CoA carboxylase, alpha subunit:Uncharacterized protein conserved in bacteria:Predicted multitransmembrane protein:NAD+--asparagine ADP-ribosyltransferase:Amino acid transport and metabolism:Carbohydrate transport and metabolism:Lipid transport and metabolism:Transcription:Replication, recombination and repair:Cell wall/membrane/envelope biogenesis:General function prediction only:Function unknown:Signal transduction mechanisms:nagA:accC:BCCP:murD:T7_EssB:T7SS_EssA_Firm:T7_EssCb_Firm:WXG100_ESAT6:Protein fate:Biosynthesis:Fatty acid and phospholipid metabolism:Amino sugars:Central intermediary metabolism:Metabolism:Poorly characterized:Cellular processes and signaling:Information storage and processing:Biosynthesis and degradation of murein sacculus and peptidoglycan:Cell envelope:Protein and peptide secretion and trafficking" 45 "Glutamate dehydrogenase/leucine dehydrogenase:Glycosyltransferase:Membrane-associated phospholipid phosphatase:Putative intracellular protease/amidase:Regulators of stationary/sporulation gene expression:Uncharacterized protein conserved in bacteria:Uncharacterized conserved protein:Amino acid transport and metabolism:Lipid transport and metabolism:Transcription:Cell wall/membrane/envelope biogenesis:General function prediction only:Function unknown:not_thiJ:lp_hng_hel_AbrB:beta_rpt_yvtn:SASP_tlp:Information storage and processing:General:Unknown function:Poorly characterized:Cellular processes:DNA interactions:Regulatory functions:Sporulation and germination:Metabolism:Cellular processes and signaling" 46 "Energy production and conversion:Nitrogen regulatory protein PII:ABC-type multidrug transport system, ATPase component:Membrane-associated lipoprotein involved in thiamine biosynthesis:Phosphatidylserine/phosphatidylglycerophosphate/cardiolipin synthases and related enzymes:Nitrogenase molybdenum-iron protein, alpha and beta chains:Uncharacterized protein conserved in bacteria:Amino acid transport and metabolism:Coenzyme transport and metabolism:Lipid transport and metabolism:Function unknown:nifB:prismane_assoc:Defense mechanisms:Electron transport:Energy metabolism:Nitrogen fixation:Central intermediary metabolism:Cellular processes and signaling:Metabolism:Poorly characterized" 47 "Xaa-Pro aminopeptidase:Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase]:Molecular chaperone (small heat shock protein):Molecular chaperone:Predicted hydrolases of the HAD superfamily:Molecular chaperone GrpE (heat shock protein):Asp-tRNAAsn/Glu-tRNAGln amidotransferase C subunit:Metal-dependent hydrolases of the beta-lactamase superfamily II:Uncharacterized protein conserved in bacteria:Methylglyoxal synthase:LuxS protein involved in autoinducer AI2 synthesis:Ribosomal protein L11 methylase:Regulator of polyketide synthase expression:Copper chaperone:Arginine kinase:Uncharacterized protein conserved in bacteria:Uncharacterized protein with conserved CXXC pairs:Predicted acetyltransferase:Predicted membrane protein:Transcriptional repressor of class III stress genes:Amino acid transport and metabolism:Carbohydrate transport and metabolism:Coenzyme transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:Posttranslational modification, protein turnover, chaperones:Inorganic ion transport and metabolism:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:Function unknown:Signal transduction mechanisms:Cof-subfamily:gatC:MGSA:prmA:DegV:prok_dnaK:TIGR04076:Unknown function:Protein folding and stabilization:Protein fate:Ribosomal proteins: synthesis and modification:tRNA aminoacylation:Protein synthesis:Other:Energy metabolism:Metabolism:Poorly characterized:Cellular processes and signaling:Information storage and processing:General:Enzymes of unknown specificity" 48 "ATPases involved in chromosome partitioning:Sugar transferases involved in lipopolysaccharide synthesis:Uncharacterized proteins involved in stress response, homologs of TerZ and putative cAMP-binding protein CABP1:Predicted kinase related to galactokinase and mevalonate kinase:Uncharacterized paraquat-inducible protein B:Fucose 4-O-acetylase and related acetyltransferases:Uncharacterized protein involved in tellurite resistance:Capsular polysaccharide biosynthesis protein:Uncharacterized protein involved in stress response:Predicted sensor domain:Cell cycle control, cell division, chromosome partitioning:Carbohydrate transport and metabolism:Transcription:Cell wall/membrane/envelope biogenesis:Inorganic ion transport and metabolism:General function prediction only:Function unknown:Signal transduction mechanisms:eps_fam:Information storage and processing:Carbohydrates, organic alcohols, and acids:Transport and binding proteins:Poorly characterized:Metabolism:Cellular processes and signaling" 49 "Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases:Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases:Glutaredoxin and related proteins:Fe2+/Zn2+ uptake regulation proteins:Predicted thioesterase:ATPases involved in chromosome partitioning:Uncharacterized protein conserved in bacteria:Predicted transcriptional regulators:Predicted transcriptional regulators:Nicotinic acid phosphoribosyltransferase:Uncharacterized proteins, homologs of microcin C7 resistance protein MccF:Putative NADPH-quinone reductase (modulator of drug activity B):Cell cycle control, cell division, chromosome partitioning:Amino acid transport and metabolism:Nucleotide transport and metabolism:Carbohydrate transport and metabolism:Coenzyme transport and metabolism:Transcription:Posttranslational modification, protein turnover, chaperones:Inorganic ion transport and metabolism:General function prediction only:Function unknown:TIGR00051:parB_part:DegV:NAPRTase_put:dipeptidaselike:GlrX_YruB:Defense mechanisms:Biosynthesis of cofactors, prosthetic groups, and carriers:General:Unknown function:Pyridine nucleotides:Information storage and processing:Cellular processes and signaling:Metabolism:Poorly characterized" 50 "ABC-type polar amino acid transport system, ATPase component:ABC-type antimicrobial peptide transport system, ATPase component:UDP-glucose pyrophosphorylase:Phosphotransferase system mannitol/fructose-specific IIA domain (Ntr-type):Transcriptional regulators:ABC-type oligopeptide transport system, periplasmic component:Amino acid transport and metabolism:Carbohydrate transport and metabolism:Transcription:Cell wall/membrane/envelope biogenesis:Signal transduction mechanisms:galU:Defense mechanisms:Information storage and processing:Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides:Cell envelope:Metabolism:Cellular processes and signaling" 51 "Energy production and conversion:Aspartyl-tRNA synthetase:Predicted metal-dependent hydrolase:4-hydroxybenzoate polyprenyltransferase and related prenyltransferases:ATPases with chaperone activity, ATP-binding subunit:Lipoprotein signal peptidase:Predicted permease:Diacylglycerol kinase:Collagenase and related proteases:Phosphopentomutase:Hydrolases of the alpha/beta superfamily:Cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes:Mismatch repair ATPase (MutS family):RecG-like helicase:Inorganic pyrophosphatase/exopolyphosphatase:Uncharacterized membrane protein:Uncharacterized low-complexity proteins:Recombinational DNA repair protein (RecF pathway):Predicted membrane-associated HD superfamily hydrolase:Uncharacterized conserved protein:Signal transduction histidine kinase regulating citrate/malate metabolism:Response regulator containing CheY-like receiver and SARP domains:Uncharacterized conserved protein, possibly involved in methylthioadenosine recycling:Site-specific recombinase XerD:Amino acid transport and metabolism:Carbohydrate transport and metabolism:Coenzyme transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:Replication, recombination and repair:Cell wall/membrane/envelope biogenesis:Posttranslational modification, protein turnover, chaperones:General function prediction only:Function unknown:Signal transduction mechanisms:TIGR00043:lspA:HDIG:aspS_bact:reco:recG:mutS2:HAD-SF-IB:deoB:recomb_XerD:ClpA:spo_II_M:Intracellular trafficking, secretion, and vesicular transport:Purines, pyrimidines, nucleosides, and nucleotides:tRNA aminoacylation:Metabolism:Cellular processes and signaling:Information storage and processing:Enzymes of unknown specificity:Unknown function:Sporulation and germination:Cellular processes:Degradation of proteins, peptides, and glycopeptides:Protein and peptide secretion and trafficking:Protein fate:Poorly characterized:Other:Protein synthesis:DNA replication, recombination, and repair:Other:DNA metabolism:Other" 52 "Predicted Co/Zn/Cd cation transporters:Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis:Predicted phosphatase/phosphohexomutase:Bacterial cell division membrane protein:ABC-type metal ion transport system, periplasmic component/surface adhesin:Predicted membrane protein:Predicted membrane protein:Exopolysaccharide biosynthesis protein:Cell cycle control, cell division, chromosome partitioning:Cell wall/membrane/envelope biogenesis:Inorganic ion transport and metabolism:General function prediction only:Function unknown:CDF:HAD-SF-IA-v3:Metabolism:Cellular processes and signaling:Enzymes of unknown specificity:Unknown function:Cations and iron carrying compounds:Transport and binding proteins:Poorly characterized" 53 "Uncharacterized conserved protein:Molybdopterin biosynthesis enzymes:tmRNA-binding protein:Parvulin-like peptidyl-prolyl isomerase:DNA-directed RNA polymerase specialized sigma subunit:Flagellin and related hook-associated proteins:Histidinol phosphatase and related hydrolases of the PHP family:Site-specific recombinases, DNA invertase Pin homologs:Uncharacterized protein conserved in bacteria:Uncharacterized homolog of the cytoplasmic domain of flagellar protein FhlB:Endoglucanase:Dipeptide/tripeptide permease:Response regulator of the LytR/AlgR family:Signal transduction histidine kinase, nitrogen specific:Site-specific recombinase XerD:Signal transduction histidine kinase:Amino acid transport and metabolism:Carbohydrate transport and metabolism:Coenzyme transport and metabolism:Transcription:Replication, recombination and repair:Cell motility:Posttranslational modification, protein turnover, chaperones:General function prediction only:Function unknown:Signal transduction mechanisms:smpB:TIGR00242:efflux_EmrB:hisJ_fam:spore_sigI:General:Unknown function:Sporulation and germination:Cellular processes:Other:Transport and binding proteins:Other:Protein synthesis:Metabolism:Poorly characterized:Cellular processes and signaling:Information storage and processing" 54 "Type II secretory pathway, component PulF:Type II secretory pathway, pseudopilin PulG:Predicted HD-superfamily hydrolase:Phage anti-repressor protein:Mu-like prophage protein Com:Phage terminase-like protein, large subunit:Plasmid rolling circle replication initiator protein and truncated derivatives:Transcription:Replication, recombination and repair:Cell motility:General function prediction only:phage_rep_org_N:IV_pilin_GFxxxE:Intracellular trafficking, secretion, and vesicular transport:Protein and peptide secretion and trafficking:Protein fate:Information storage and processing:Cellular processes and signaling:Poorly characterized:Prophage functions:Mobile and extrachromosomal element functions" 55 "Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase:Chorismate synthase:5-enolpyruvylshikimate-3-phosphate synthase:Shikimate 5-dehydrogenase:Prephenate dehydrogenase:ABC-type Co2+ transport system, permease component:3-dehydroquinate synthetase:Cobalamin-5-phosphate synthase:ABC-type Fe3+-hydroxamate transport system, periplasmic component:ABC-type cobalt transport system, permease component CbiQ and related transporters:Shikimate kinase:3-dehydroquinate dehydratase II:ABC-type cobalt transport system, ATPase component:NaMN:DMB phosphoribosyltransferase:Cobalamin biosynthesis protein CbiG:Precorrin isomerase:Precorrin-6x reductase:3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase:Protein involved in propanediol utilization, and related proteins (includes coumermycin biosynthetic protein), possible kinase:Cobalamin biosynthesis protein CbiK, Co2+ chelatase:Amino acid transport and metabolism:Coenzyme transport and metabolism:Inorganic ion transport and metabolism:Secondary metabolites biosynthesis, transport and catabolism:aroC:cobS:aroE:precor6x_red:aroQ:cbiO:aroA:aroB:DAHP_synth_Bsub:CbiQ_TIGR:cobT_DBIPRT:Metabolism:Biosynthesis of cofactors, prosthetic groups, and carriers:Aromatic amino acid family:Amino acid biosynthesis:Cations and iron carrying compounds:Transport and binding proteins:Heme, porphyrin, and cobalamin" 56 "Predicted sugar kinase:Fructose-2,6-bisphosphatase:Spermidine/putrescine-binding periplasmic protein:Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains):Precorrin-3B methylase:ABC-type spermidine/putrescine transport system, permease component II:Cobyric acid synthase:Cobyrinic acid a,c-diamide synthase:Cobalamin biosynthesis protein CbiD:Precorrin isomerase:Adenosyl cobinamide kinase/adenosyl cobinamide phosphate guanylyltransferase:Methylase involved in ubiquinone/menaquinone biosynthesis:Precorrin-6B methylase 2:Precorrin-2 methylase:Outer membrane lipoprotein-sorting protein:Precorrin-4 methylase:Amino acid transport and metabolism:Carbohydrate transport and metabolism:Coenzyme transport and metabolism:Cell wall/membrane/envelope biogenesis:yjeF_cterm:cbiD:cobQ:cobB:cobM_cbiF:cobJ_cbiH:cobI_cbiL:CbiT:ribazole_cobC:Metabolism:Heme, porphyrin, and cobalamin:Biosynthesis of cofactors, prosthetic groups, and carriers:General:Unknown function:Cellular processes and signaling" 57 "Energy production and conversion:Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), B subunit:N-formylmethionyl-tRNA deformylase:Signal transduction histidine kinase:Nitroreductase:Mannose-1-phosphate guanylyltransferase:Acyl carrier protein phosphodiesterase:Transcriptional regulators of sugar metabolism:Rubrerythrin:Small primase-like proteins (Toprim domain):D-alanyl-D-alanine carboxypeptidase:Transcriptional regulators:NTP pyrophosphohydrolases containing a Zn-finger, probably nucleic-acid-binding:Methenyl tetrahydrofolate cyclohydrolase:Uncharacterized protein conserved in bacteria:Uncharacterized conserved small protein:Amino acid transport and metabolism:Carbohydrate transport and metabolism:Lipid transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:Replication, recombination and repair:Cell wall/membrane/envelope biogenesis:Function unknown:Signal transduction mechanisms:pept_deformyl:5S_RNA_mat_M5:gyrB:Cellular processes and signaling:Information storage and processing:Protein modification and repair:Protein fate:RNA processing:Transcription:DNA replication, recombination, and repair:DNA metabolism:Metabolism:Poorly characterized" 58 "Homoserine kinase:Predicted EndoIII-related endonuclease:1-acyl-sn-glycerol-3-phosphate acyltransferase:Transcriptional regulator:Hypoxanthine-guanine phosphoribosyltransferase:Bacterial cell division membrane protein:Transcription-repair coupling factor (superfamily II helicase):Uncharacterized protein conserved in bacteria:Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase:FOG: FHA domain:Uncharacterized ABC-type transport system, periplasmic component/surface lipoprotein:Uncharacterized bacitracin resistance protein:Cystathionine beta-lyase family protein involved in aluminum resistance:Exopolysaccharide biosynthesis protein related to N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase:Cell cycle control, cell division, chromosome partitioning:Amino acid transport and metabolism:Nucleotide transport and metabolism:Carbohydrate transport and metabolism:Lipid transport and metabolism:Transcription:Replication, recombination and repair:Inorganic ion transport and metabolism:General function prediction only:Function unknown:Signal transduction mechanisms:TIGR00147:thrB:AGP_acyltrn:mfd:undec_PP_bacA:DegV:nth:HGPRTase:spore_yabP:Defense mechanisms:Cellular processes and signaling:Information storage and processing:Biosynthesis and degradation of murein sacculus and peptidoglycan:Cell envelope:Aspartate family:Amino acid biosynthesis:General:Enzymes of unknown specificity:Unknown function:Sporulation and germination:Cellular processes:DNA replication, recombination, and repair:DNA metabolism:Salvage of nucleosides and nucleotides:Purines, pyrimidines, nucleosides, and nucleotides:Biosynthesis:Fatty acid and phospholipid metabolism:Metabolism:Poorly characterized" 59 "Energy production and conversion:Ribosomal protein S2:F0F1-type ATP synthase, beta subunit:F0F1-type ATP synthase, alpha subunit:Ribosomal protein L5:Ribosomal protein S11:Ribosomal protein L15:Ribosomal protein L17:F0F1-type ATP synthase, gamma subunit:F0F1-type ATP synthase, subunit a:Superfamily II DNA and RNA helicases:F0F1-type ATP synthase, subunit c/Archaeal/vacuolar-type H+-ATPase, subunit K:Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, alpha subunit:F0F1-type ATP synthase, delta subunit (mitochondrial oligomycin sensitivity protein):Parvulin-like peptidyl-prolyl isomerase:Ferredoxin:Transglutaminase-like enzymes, putative cysteine proteases:Predicted metal-binding, possibly nucleic acid-binding protein:Thymidine kinase:Electron transfer flavoprotein, alpha subunit:Uncharacterized protein conserved in bacteria:Predicted flavin-nucleotide-binding protein:Uncharacterized protein with conserved CXXC pairs:Antirepressor regulating drug resistance, predicted signal transduction N-terminal membrane component:Predicted permease, DMT superfamily:Amino acid transport and metabolism:Nucleotide transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:Replication, recombination and repair:Posttranslational modification, protein turnover, chaperones:General function prediction only:Function unknown:Signal transduction mechanisms:L17:atpA:rpsB_bact:atpD:rplO_bact:ATP_synt_delta:ATPsyn_F1gamma:ATP_synt_c:pyruv_ox_red:spore_ylbJ:spore_YpeB:bact_S11:Poorly characterized:Cellular processes and signaling:Information storage and processing:Sporulation and germination:Cellular processes:Ribosomal proteins: synthesis and modification:Protein synthesis:ATP-proton motive force interconversion:Energy metabolism:Metabolism" 60 "Biotin carboxyl carrier protein:Predicted transcriptional regulators:Predicted transcriptional regulators:Beta-galactosidase:HD-GYP domain:Beta-lactamase class A:Putative peptidoglycan-binding domain-containing protein:Uncharacterized protein conserved in bacteria:Uncharacterized protein containing a NRPS condensation (elongation) domain:Carbohydrate transport and metabolism:Lipid transport and metabolism:Transcription:Cell wall/membrane/envelope biogenesis:General function prediction only:Function unknown:Signal transduction mechanisms:Defense mechanisms:Information storage and processing:Poorly characterized:Metabolism:Cellular processes and signaling" 61 "Ribosomal protein S2:Ribosomal protein L1:Ribosomal protein L27:Ribosomal protein L7/L12:Ribosomal protein S18:Ribosomal protein L21:Translation initiation factor 3 (IF-3):Ribosomal protein L35:Ribosomal protein L20:Ribosomal protein S6:Single-stranded DNA-binding protein:Enoyl-CoA hydratase/carnithine racemase:Predicted metal-binding, possibly nucleic acid-binding protein:Predicted ribosomal protein:Lipid transport and metabolism:Translation, ribosomal structure and biogenesis:Replication, recombination and repair:General function prediction only:rpmI_bact:L21:L27:S18:S6:infC:ssb:L12:rpsB_bact:rplT_bact:rplA_bact:DNA metabolism:DNA replication, recombination, and repair:Protein synthesis:Ribosomal proteins: synthesis and modification:Translation factors:Information storage and processing:Poorly characterized:Metabolism" 62 "Energy production and conversion:Kef-type K+ transport systems, membrane components:NTP pyrophosphohydrolases including oxidative damage repair enzymes:2-polyprenylphenol hydroxylase and related flavodoxin oxidoreductases:DNA polymerase III, epsilon subunit and related 3'-5' exonucleases:ABC-type multidrug transport system, ATPase component:ABC-type transport system involved in multi-copper enzyme maturation, permease component:Amidases related to nicotinamidase:Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily:Predicted small molecule binding protein (contains 3H domain):Uncharacterized oxidoreductases, Fe-dependent alcohol dehydrogenase family:Predicted periplasmic or secreted lipoprotein:Uncharacterized protein involved in plasmid maintenance:Uncharacterized conserved protein:Coenzyme transport and metabolism:Replication, recombination and repair:Cell wall/membrane/envelope biogenesis:Inorganic ion transport and metabolism:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:Function unknown:LPXTG_anchor:Defense mechanisms:Poorly characterized:Metabolism:Cellular processes and signaling:Information storage and processing:Other:Cell envelope" 63 "Energy production and conversion:Peptidyl-tRNA hydrolase:Single-stranded DNA-binding protein:Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, alpha subunit:Predicted membrane-associated Zn-dependent proteases 1:Transcription elongation factor:Actin-like ATPase involved in cell morphogenesis:Predicted glycosyltransferases:LuxS protein involved in autoinducer AI2 synthesis:Predicted transcriptional regulator:Uncharacterized protein with SCP/PR1 domains:Endoglucanase:Signal transduction histidine kinase regulating citrate/malate metabolism:Uncharacterized conserved protein:Response regulator containing a CheY-like receiver domain and an HD-GYP domain:Uncharacterized conserved protein:Cell cycle control, cell division, chromosome partitioning:Carbohydrate transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:Replication, recombination and repair:Cell wall/membrane/envelope biogenesis:General function prediction only:Function unknown:Signal transduction mechanisms:pth:ssb:rrf2_super:mreB:greA:pyruv_ox_red:spore_IV_B:spore_YkwD:DNA replication, recombination, and repair:DNA metabolism:Sporulation and germination:Information storage and processing:Cellular processes and signaling:Metabolism:Poorly characterized:Cell envelope:General:Unknown function:Biosynthesis and degradation of murein sacculus and peptidoglycan:Cellular processes:Other:Protein synthesis:Transcription factors:Transcription" 64 "Xanthosine triphosphate pyrophosphatase:Tyrosyl-tRNA synthetase:Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), B subunit:ATPases with chaperone activity, ATP-binding subunit:DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32):Uridine kinase:MoxR-like ATPases:Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains):Predicted membrane-associated Zn-dependent proteases 1:Predicted transcriptional regulators containing the CopG/Arc/MetJ DNA-binding domain and a metal-binding domain:GTPase:16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases:Uncharacterized protein conserved in bacteria:Uncharacterized protein conserved in bacteria:Transcriptional regulators of sugar metabolism:Acetyltransferases, including N-acetylases of ribosomal proteins:D-alanyl-D-alanine carboxypeptidase:Transcriptional regulators:L-serine deaminase:Predicted flavoproteins:Pyridoxal/pyridoxine/pyridoxamine kinase:Predicted SAM-dependent methyltransferase:Uncharacterized protein conserved in bacteria:Predicted transcriptional regulator containing CBS domains:Uncharacterized protein conserved in bacteria:Amino acid transport and metabolism:Nucleotide transport and metabolism:Carbohydrate transport and metabolism:Coenzyme transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:Replication, recombination and repair:Cell wall/membrane/envelope biogenesis:Posttranslational modification, protein turnover, chaperones:General function prediction only:Function unknown:TIGR00042:TIGR00054:TIGR00093:small_GTP:tyrS:TIGR00275:sda_beta:DegV:gyrB:sigma70-ECF:tRNA and rRNA base modification:tRNA aminoacylation:Protein synthesis:DNA replication, recombination, and repair:DNA metabolism:Glycolysis/gluconeogenesis:Energy metabolism:Metabolism:Poorly characterized:Cellular processes and signaling:Information storage and processing:General:Enzymes of unknown specificity:Unknown function:Degradation of proteins, peptides, and glycopeptides:Protein fate" 65 "Predicted N6-adenine-specific DNA methylase:ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component:NADPH-dependent glutamate synthase beta chain and related oxidoreductases:Sugar kinases, ribokinase family:Topoisomerase IA:Predicted hydrolases of the HAD superfamily:Phosphoenolpyruvate synthase/pyruvate phosphate dikinase:Glycine/D-amino acid oxidases (deaminating):3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratases:Methyl-accepting chemotaxis protein:Adenine deaminase:Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases):Uncharacterized ABC-type transport system, permease component:Ferritin-like protein:Transcriptional regulators:NaMN:DMB phosphoribosyltransferase:Signal transduction histidine kinase:NAD+--asparagine ADP-ribosyltransferase:Amino acid transport and metabolism:Nucleotide transport and metabolism:Carbohydrate transport and metabolism:Coenzyme transport and metabolism:Lipid transport and metabolism:Transcription:Replication, recombination and repair:Cell motility:Inorganic ion transport and metabolism:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:Signal transduction mechanisms:Cof-subfamily:topB:ade:oligo_HPY:fabZ:kduD:cobT_DBIPRT:Enzymes of unknown specificity:Unknown function:Amino acids, peptides and amines:Transport and binding proteins:DNA replication, recombination, and repair:DNA metabolism:Salvage of nucleosides and nucleotides:Purines, pyrimidines, nucleosides, and nucleotides:Biosynthesis:Fatty acid and phospholipid metabolism:Biosynthesis and degradation of polysaccharides:Energy metabolism:Metabolism:Poorly characterized:Cellular processes and signaling:Information storage and processing:Heme, porphyrin, and cobalamin:Biosynthesis of cofactors, prosthetic groups, and carriers" 66 "Di- and tricarboxylate transporters:Zn-dependent hydrolases, including glyoxylases:Superfamily II DNA and RNA helicases:Topoisomerase IA:Predicted hydrolases of the HAD superfamily:Transcriptional regulator:Multimeric flavodoxin WrbA:Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain:Methyl-accepting chemotaxis protein:Flagellin and related hook-associated proteins:Transcriptional regulators:Ketopantoate reductase:4-diphosphocytidyl-2C-methyl-D-erythritol 2-phosphate synthase:Response regulator with putative antiterminator output domain:Uncharacterized protein conserved in bacteria:Coenzyme transport and metabolism:Lipid transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:Replication, recombination and repair:Cell motility:Inorganic ion transport and metabolism:General function prediction only:Function unknown:Signal transduction mechanisms:Cof-subfamily:ispE:dass:topB:Information storage and processing:Other:Biosynthesis of cofactors, prosthetic groups, and carriers:Enzymes of unknown specificity:Unknown function:Cations and iron carrying compounds:Transport and binding proteins:DNA replication, recombination, and repair:DNA metabolism:Metabolism:Poorly characterized:Cellular processes and signaling" 67 "Uncharacterized conserved protein:Pseudouridylate synthases, 23S RNA-specific:Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily):Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain:ABC-type multidrug transport system, ATPase component:ABC-type transport system involved in multi-copper enzyme maturation, permease component:Transcriptional regulator:Acetyltransferases, including N-acetylases of ribosomal proteins:Beta-lactamase class C and other penicillin binding proteins:Putative homoserine kinase type II (protein kinase fold):Barstar, RNAse (barnase) inhibitor:Uncharacterized conserved protein (small basic protein):Uncharacterized distant relative of cell wall-associated hydrolases:Uncharacterized protein conserved in bacteria:Beta-mannanase:Predicted membrane protein:Carbohydrate transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:General function prediction only:Function unknown:Signal transduction mechanisms:rluA_subfam:TIGR00106:lytR_cpsA_psr:Defense mechanisms:Cellular processes and signaling:Information storage and processing:General:Unknown function:Poorly characterized:Protein synthesis:Other:Regulatory functions:tRNA and rRNA base modification:Metabolism" 68 "Energy production and conversion:3-oxoacyl-(acyl-carrier-protein) synthase:Molybdenum cofactor biosynthesis enzyme:Molybdopterin biosynthesis enzymes:ABC-type Fe3+-hydroxamate transport system, periplasmic component:Multimeric flavodoxin WrbA:Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, gamma subunit:ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components:ABC-type antimicrobial peptide transport system, ATPase component:DNA-directed RNA polymerase specialized sigma subunit:Glycosyl transferases, related to UDP-glucuronosyltransferase:Phosphopantetheinyl transferase:Membrane protein involved in the export of O-antigen and teichoic acid:Uncharacterized protein conserved in bacteria:Carbohydrate transport and metabolism:Coenzyme transport and metabolism:Lipid transport and metabolism:Transcription:Inorganic ion transport and metabolism:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:Function unknown:moaC:spore_sigI:fabF:IOR_beta:Defense mechanisms:Information storage and processing:Molybdopterin:Biosynthesis of cofactors, prosthetic groups, and carriers:Sporulation and germination:Cellular processes:Biosynthesis:Fatty acid and phospholipid metabolism:Cellular processes and signaling:Metabolism:Poorly characterized" 69 "ABC-type nitrate/sulfonate/bicarbonate transport system, permease component:FOG: Ankyrin repeat:Predicted permeases:5'-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases:ABC-type metal ion transport system, periplasmic component/surface adhesin:ABC-type Mn2+/Zn2+ transport systems, permease components:ABC-type Mn/Zn transport systems, ATPase component:ABC-type antimicrobial peptide transport system, ATPase component:Flagellin and related hook-associated proteins:Predicted transcriptional regulators:Uncharacterized bacitracin resistance protein:Predicted membrane protein:Uncharacterized protein conserved in bacteria:Nucleotide transport and metabolism:Transcription:Cell motility:Inorganic ion transport and metabolism:General function prediction only:Function unknown:undec_PP_bacA:Defense mechanisms:Poorly characterized:Metabolism:Cellular processes and signaling:Information storage and processing:Biosynthesis and degradation of murein sacculus and peptidoglycan:Cell envelope" 70 "Energy production and conversion:Chloride channel protein EriC:Acetyltransferase (isoleucine patch superfamily):Fe2+ transport system protein B:Glutathione peroxidase:Fructose-2,6-bisphosphatase:ABC-type antimicrobial peptide transport system, permease component:Signal transduction histidine kinase:Methyl-accepting chemotaxis protein:Acylphosphatases:Uncharacterized protein conserved in bacteria:Predicted inhibitor of MCP methylation, homolog of CheC:2'-5' RNA ligase:HD-GYP domain:Carbohydrate transport and metabolism:Translation, ribosomal structure and biogenesis:Cell motility:Posttranslational modification, protein turnover, chaperones:Inorganic ion transport and metabolism:General function prediction only:Function unknown:Signal transduction mechanisms:HDIG:feoB:DegV:para_beta_helix:Defense mechanisms:General:Unknown function:Poorly characterized:Transport and binding proteins:Cations and iron carrying compounds:Metabolism:Cellular processes and signaling:Information storage and processing" 71 "Energy production and conversion:Superfamily II DNA/RNA helicases, SNF2 family:Transcriptional regulator:Fe-S oxidoreductases:Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain:ABC-type multidrug transport system, ATPase component:D-alanine-D-alanine ligase and related ATP-grasp enzymes:Sortase and related acyltransferases:Arsenate reductase and related proteins, glutaredoxin family:Uncharacterized protein conserved in bacteria:ABC-type Na+ efflux pump, permease component:Predicted transcriptional regulators:Putative NADPH-quinone reductase (modulator of drug activity B):Predicted hydrolase of the alpha/beta superfamily:Predicted nucleotidyltransferase:Transposase and inactivated derivatives:Short-chain dehydrogenase involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein):Predicted membrane protein:Uncharacterized protein conserved in bacteria:Transcription:Replication, recombination and repair:Cell wall/membrane/envelope biogenesis:Inorganic ion transport and metabolism:General function prediction only:Function unknown:Signal transduction mechanisms:Defense mechanisms:Poorly characterized:Metabolism:Cellular processes and signaling:Information storage and processing" 72 "Dihydroorotase and related cyclic amidohydrolases:Predicted phosphatase/phosphohexomutase:Endonuclease IV:Predicted dehydrogenases and related proteins:Exonuclease III:6-pyruvoyl-tetrahydropterin synthase:16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases:Uncharacterized Fe-S protein PflX, homolog of pyruvate formate lyase activating proteins:Predicted metal-dependent hydrolase:Transcriptional regulators:Uncharacterized conserved protein:Transcriptional regulator/sugar kinase:Cell division protein:HD-GYP domain:Predicted hydrolase of the alpha/beta superfamily:Predicted esterase of the alpha-beta hydrolase superfamily:Predicted integral membrane protein:Cell cycle control, cell division, chromosome partitioning:Nucleotide transport and metabolism:Carbohydrate transport and metabolism:Coenzyme transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:Replication, recombination and repair:General function prediction only:Function unknown:Signal transduction mechanisms:TIGR00093:exoDNase_III:HDIG:pyrC_multi:HAD-SF-IA-v3:release_rtcB:6_pyr_pter_rel:tRNA and rRNA base modification:Other:Protein synthesis:DNA replication, recombination, and repair:DNA metabolism:Pyrimidine ribonucleotide biosynthesis:Purines, pyrimidines, nucleosides, and nucleotides:Metabolism:Poorly characterized:Cellular processes and signaling:Information storage and processing:Enzymes of unknown specificity:Unknown function" 73 "Glycosyltransferases involved in cell wall biogenesis:Signal transduction histidine kinase:Transcriptional regulator:Oxygen-sensitive ribonucleoside-triphosphate reductase:Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily:Acetyltransferases, including N-acetylases of ribosomal proteins:Arginine/lysine/ornithine decarboxylases:Phosphotransferase system IIA components:FOG: EAL domain:Uncharacterized protein conserved in bacteria:Uncharacterized protein conserved in bacteria:Uncharacterized conserved protein:Copper chaperone:Uncharacterized protein conserved in bacteria:Uncharacterized protein conserved in bacteria:Amino acid transport and metabolism:Nucleotide transport and metabolism:Carbohydrate transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:Cell wall/membrane/envelope biogenesis:Inorganic ion transport and metabolism:Function unknown:Signal transduction mechanisms:GGDEF:PTBA:TIGR02271:NrdD:SASP_H:spore_CotS:PTS:Signal transduction:Sporulation and germination:Cellular processes:2'-Deoxyribonucleotide metabolism:Purines, pyrimidines, nucleosides, and nucleotides:Metabolism:Poorly characterized:Cellular processes and signaling:Information storage and processing:Other" 74 "Signal transduction histidine kinase:Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain:Methyl-accepting chemotaxis protein:Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs:Transcriptional regulator:Predicted transcriptional regulators:DNA replication protein:AraC-type DNA-binding domain-containing proteins:Lipid A core - O-antigen ligase and related enzymes:Transposase and inactivated derivatives:Predicted membrane protein:Amino acid transport and metabolism:Transcription:Replication, recombination and repair:Cell wall/membrane/envelope biogenesis:Cell motility:Function unknown:Signal transduction mechanisms:integ_TIGR01906:Poorly characterized:Metabolism:Cellular processes and signaling:Information storage and processing" 75 "Galactokinase:Methyl-accepting chemotaxis protein:UDP-glucose 4-epimerase:ABC-type sugar transport systems, permease components:FOG: LysM repeat:Alpha-glucosidases, family 31 of glycosyl hydrolases:ABC-type sugar transport system, periplasmic component:Glucuronate isomerase:Na+/melibiose symporter and related transporters:3-carboxymuconate cyclase:Pectate lyase:Arabinogalactan endo-1,4-beta-galactosidase:Galactose-1-phosphate uridyltransferase:Uncharacterized protein with a bacterial SH3 domain homologue:FOG: Glucan-binding domain (YG repeat):Carbohydrate transport and metabolism:Cell wall/membrane/envelope biogenesis:Cell motility:General function prediction only:Function unknown:Signal transduction mechanisms:gal_kin:gph:galE:galT_2:Carbohydrates, organic alcohols, and acids:Transport and binding proteins:Sugars:Energy metabolism:Metabolism:Poorly characterized:Cellular processes and signaling" 76 "Site-specific DNA methylase:tRNA-(guanine-N1)-methyltransferase:Protein-tyrosine-phosphatase:Pseudouridylate synthases, 23S RNA-specific:tRNA nucleotidyltransferase/poly(A) polymerase:Bacterial cell division membrane protein:RimM protein, required for 16S rRNA processing:Predicted amidophosphoribosyltransferases:ABC-type multidrug transport system, ATPase and permease components:Cold shock proteins:Putative transcriptional regulator, homolog of Bvg accessory factor:Uncharacterized conserved protein:AT-rich DNA-binding protein:ACT domain-containing protein:Cell cycle control, cell division, chromosome partitioning:Translation, ribosomal structure and biogenesis:Transcription:Replication, recombination and repair:General function prediction only:Function unknown:Signal transduction mechanisms:rluA_subfam:trmD:baf:dcm:rodA_shape:16S_RimM:Defense mechanisms:RNA processing:Transcription:DNA replication, recombination, and repair:DNA metabolism:tRNA and rRNA base modification:Cellular processes and signaling:Information storage and processing:Pantothenate and coenzyme A:Biosynthesis of cofactors, prosthetic groups, and carriers:Cell division:Cellular processes:Poorly characterized:Protein synthesis" 77 "Energy production and conversion:Na+-driven multidrug efflux pump:Nitroreductase:Cell wall-associated hydrolases (invasion-associated proteins):ABC-type multidrug transport system, ATPase component:Metal-dependent hydrolases of the beta-lactamase superfamily III:Predicted transcriptional regulators:Transcriptional regulators:SOS-response transcriptional repressors (RecA-mediated autopeptidases):Phosphotransferase system IIA components:Cyclopropane fatty acid synthase and related methyltransferases:Xanthine/uracil permeases:Permeases:Uncharacterized conserved protein:Bacterial surface proteins containing Ig-like domains:Nucleotide transport and metabolism:Carbohydrate transport and metabolism:Transcription:Cell wall/membrane/envelope biogenesis:Cell motility:General function prediction only:Function unknown:Signal transduction mechanisms:lexA:matE:ncs2:PTBA:RNase_Z:spore_BofA:Defense mechanisms:Poorly characterized:Metabolism:Cellular processes and signaling:Information storage and processing:PTS:Signal transduction:Sporulation and germination:Cellular processes:Other:Nucleosides, purines and pyrimidines:Transport and binding proteins:RNA processing:Transcription:DNA interactions:Regulatory functions" 78 "Energy production and conversion:GTPases - translation elongation factors:Hydrogenase maturation factor:ATPase components of ABC transporters with duplicated ATPase domains:Ribosomal protein S4 and related proteins:Phosphoglycerate mutase 1:UDP-N-acetylglucosamine enolpyruvyl transferase:Predicted hydrolase (HAD superfamily):Predicted glycosyltransferases:ABC-type Na+ efflux pump, permease component:Osmosensitive K+ channel histidine kinase:High-affinity K+ transport system, ATPase chain B:Uncharacterized conserved protein:Carbohydrate transport and metabolism:Translation, ribosomal structure and biogenesis:Cell wall/membrane/envelope biogenesis:Posttranslational modification, protein turnover, chaperones:Inorganic ion transport and metabolism:General function prediction only:Function unknown:Signal transduction mechanisms:hypD:small_GTP:rpsD_bact:murA:pgm_1:ATPase_P-type:HAD-SF-IA-v3:Information storage and processing:Enzymes of unknown specificity:Unknown function:Protein modification and repair:Protein fate:Ribosomal proteins: synthesis and modification:Protein synthesis:Poorly characterized:Biosynthesis and degradation of murein sacculus and peptidoglycan:Cell envelope:General:Metabolism:Cellular processes and signaling" 79 "Energy production and conversion:Putative translation factor (SUA5):tRNA-dihydrouridine synthase:Asp-tRNAAsn/Glu-tRNAGln amidotransferase B subunit (PET112 homolog):3-phosphoglycerate kinase:Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases:Site-specific DNA methylase:F0F1-type ATP synthase, subunit a:ATPase components of ABC transporters with duplicated ATPase domains:GMP synthase, PP-ATPase domain/subunit:Topoisomerase IA:F0F1-type ATP synthase, subunit b:Asp-tRNAAsn/Glu-tRNAGln amidotransferase C subunit:UDP-N-acetylmuramyl tripeptide synthase:Predicted transcriptional regulators:Predicted nucleotide-utilizing enzyme related to molybdopterin-biosynthesis enzyme MoeA:ABC-type cobalt transport system, ATPase component:Hemolysins and related proteins containing CBS domains:Tartrate dehydratase beta subunit/Fumarate hydratase class I, C-terminal domain:Spore coat polysaccharide biosynthesis protein F, CMP-KDO synthetase homolog:Lysophospholipase:Beta-glucosidase/6-phospho-beta-glucosidase/beta-galactosidase:Predicted metal-dependent enzyme:Predicted secreted protein:Nucleotide transport and metabolism:Carbohydrate transport and metabolism:Lipid transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:Replication, recombination and repair:Cell wall/membrane/envelope biogenesis:Inorganic ion transport and metabolism:General function prediction only:Function unknown:TIGR00057:gatA:gatB:gatC:molyb_syn:dcm:ttdB_fumA_fumB:nifR3_yhdG:guaA_Cterm:topA_bact:ATP_synt_b:ATP-proton motive force interconversion:Purines, pyrimidines, nucleosides, and nucleotides:Purine ribonucleotide biosynthesis:DNA metabolism:DNA replication, recombination, and repair:Poorly characterized:Metabolism:Cellular processes and signaling:Information storage and processing:General:Unknown function:Protein synthesis:tRNA aminoacylation:Energy metabolism" 80 "Energy production and conversion:tRNA-dihydrouridine synthase:Glucan phosphorylase:Fe2+ transport system protein B:Uncharacterized flavoproteins:NTP pyrophosphohydrolases including oxidative damage repair enzymes:FOG: CBS domain:ABC-type amino acid transport system, permease component:ABC-type amino acid transport/signal transduction systems, periplasmic component/domain:ABC-type polar amino acid transport system, ATPase component:Predicted transcriptional regulators:Uncharacterized conserved protein:Desulfoferrodoxin:AraC-type DNA-binding domain-containing proteins:Methylase involved in ubiquinone/menaquinone biosynthesis:Predicted membrane protein:Predicted oxidoreductase related to nitroreductase:Amino acid transport and metabolism:Carbohydrate transport and metabolism:Coenzyme transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:Replication, recombination and repair:Inorganic ion transport and metabolism:General function prediction only:Function unknown:Signal transduction mechanisms:small_GTP:neela_ferrous:HEQRo_perm_3TM:more_P_ylases:spore_YlmC_YmxH:General:Unknown function:Sporulation and germination:Cellular processes:Amino acids, peptides and amines:Transport and binding proteins:Electron transport:Energy metabolism:Metabolism:Poorly characterized:Cellular processes and signaling:Information storage and processing" 81 "Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain:Glycosyltransferase:Predicted Fe-S oxidoreductases:Membrane-associated phospholipid phosphatase:ABC-type multidrug transport system, ATPase component:Transcriptional regulators:Lipid transport and metabolism:Transcription:Cell wall/membrane/envelope biogenesis:Posttranslational modification, protein turnover, chaperones:General function prediction only:autotrns_rpt:rSAM_NirJ2:Defense mechanisms:Metabolism:Cellular processes and signaling:Information storage and processing:Pathogenesis:Cellular processes:Poorly characterized" 82 "Aspartyl/asparaginyl-tRNA synthetases:Superfamily II DNA and RNA helicases:Predicted permease:Signal transduction histidine kinase:Glycosyltransferases, probably involved in cell wall biogenesis:Predicted glycosyltransferases:Predicted membrane protein:Uncharacterized low-complexity proteins:Phosphotransferase system cellobiose-specific component IIC:S-adenosylmethionine decarboxylase:ABC-type sugar transport system, periplasmic component:Arginine/lysine/ornithine decarboxylases:Sugar phosphate permease:Protein containing tetrapyrrole methyltransferase domain and MazG-like (predicted pyrophosphatase) domain:Peptide chain release factor RF-3:Beta-mannanase:Signal transduction histidine kinase:Uncharacterized protein conserved in bacteria:Amino acid transport and metabolism:Carbohydrate transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:Replication, recombination and repair:Cell wall/membrane/envelope biogenesis:General function prediction only:Function unknown:Signal transduction mechanisms:small_GTP:lacE:mazG:asnS:efflux_EmrB:yihY_not_rbn:SAM_DCase_Eco:WXG100_ESAT6:Unknown function:Other:Transport and binding proteins:tRNA aminoacylation:Protein synthesis:Polyamine biosynthesis:Central intermediary metabolism:Cellular processes and signaling:Poorly characterized:Metabolism:Information storage and processing:PTS:Signal transduction:General" 83 "Energy production and conversion:Pyridoxine biosynthesis enzyme:Predicted glutamine amidotransferase involved in pyridoxine biosynthesis:Fe2+ transport system protein B:Glutathione peroxidase:Nucleoside-diphosphate-sugar epimerases:Ribosomal protein S4 and related proteins:Sugar kinases, ribokinase family:Transcriptional regulator:Nitroreductase:2-keto-3-deoxy-6-phosphogluconate aldolase:2'-5' RNA ligase:Transcriptional regulators:Ketopantoate reductase:Fe2+ transport system protein A:Predicted transcriptional regulator:Arabinose efflux permease:Carbohydrate transport and metabolism:Coenzyme transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:Cell wall/membrane/envelope biogenesis:Posttranslational modification, protein turnover, chaperones:Inorganic ion transport and metabolism:small_GTP:TIGR00343:rrf2_super:rpsD_bact:eda:PLP_synth_Pdx2:General:Unknown function:Ribosomal proteins: synthesis and modification:Protein synthesis:Entner-Doudoroff:Energy metabolism:Cellular processes and signaling:Metabolism:Information storage and processing:Pyridoxine:Biosynthesis of cofactors, prosthetic groups, and carriers" 84 "Energy production and conversion:Transketolase:Histidyl-tRNA synthetase:5,10-methylene-tetrahydrofolate dehydrogenase/Methenyl tetrahydrofolate cyclohydrolase:Glycerol-3-phosphate dehydrogenase:Glucosamine 6-phosphate synthetase, contains amidotransferase and phosphosugar isomerase domains:Orotate phosphoribosyltransferase:Membrane GTPase LepA:ATPase components of ABC transporters with duplicated ATPase domains:Superfamily II DNA and RNA helicases:Na+-driven multidrug efflux pump:rRNA methylases:ABC-type cobalt transport system, permease component CbiQ and related transporters:ABC-type proline/glycine betaine transport systems, ATPase components:ABC-type multidrug transport system, ATPase and permease components:GTPase:Ribonucleases G and E:Teichoic acid biosynthesis proteins:Uncharacterized protein conserved in bacteria:Uncharacterized protein conserved in bacteria:Uncharacterized protein conserved in bacteria:Uncharacterized protein conserved in bacteria:Amino acid transport and metabolism:Nucleotide transport and metabolism:Carbohydrate transport and metabolism:Coenzyme transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:Replication, recombination and repair:Cell wall/membrane/envelope biogenesis:Inorganic ion transport and metabolism:General function prediction only:Function unknown:small_GTP:tktlase_bact:CoA_E_activ:pyrE:hisS:wecG_tagA_cpsF:RNaseEG:matE:glmS:proV:sam_1_link_chp:Defense mechanisms:Pentose phosphate pathway:Energy metabolism:Amino sugars:Central intermediary metabolism:Protein synthesis:Cellular processes and signaling:Metabolism:Poorly characterized:Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides:Cell envelope:General:Unknown function:Other:Amino acids, peptides and amines:Transport and binding proteins:tRNA aminoacylation:Information storage and processing:Degradation of RNA:Transcription:Pyrimidine ribonucleotide biosynthesis:Purines, pyrimidines, nucleosides, and nucleotides" 85 "Energy production and conversion:Gamma-glutamyl phosphate reductase:Diaminopimelate epimerase:Glutamate 5-kinase:Malic enzyme:Pyrroline-5-carboxylate reductase:Aspartate/tyrosine/aromatic aminotransferase:Aspartokinases:ABC-type Fe3+-siderophore transport system, permease component:Predicted metal-dependent phosphoesterases (PHP family):dUTPase:Na+/H+-dicarboxylate symporters:Uncharacterized protein containing a Zn-finger-like domain:Tetrahydrodipicolinate N-succinyltransferase:Uncharacterized conserved protein:Uncharacterized protein conserved in bacteria:NAD+--asparagine ADP-ribosyltransferase:Amino acid transport and metabolism:Nucleotide transport and metabolism:Inorganic ion transport and metabolism:General function prediction only:Function unknown:Signal transduction mechanisms:proC:proA:dut:DapF:asp_kinases:proB:DapD_Ac:2'-Deoxyribonucleotide metabolism:Purines, pyrimidines, nucleosides, and nucleotides:Metabolism:Poorly characterized:Cellular processes and signaling:Glutamate family:Aspartate family:Amino acid biosynthesis" 86 "Energy production and conversion:Acyl carrier protein:Predicted dehydrogenase:Transcriptional regulator:Putative intracellular protease/amidase:Nitroreductase:FOG: CheY-like receiver:dTDP-4-dehydrorhamnose 3,5-epimerase and related enzymes:Glycerol-3-phosphate responsive antiterminator (mRNA-binding):Membrane protein involved in the export of O-antigen and teichoic acid:Response regulator of the LytR/AlgR family:Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IID:Uncharacterized protein conserved in bacteria:Leucine-rich repeat (LRR) protein:Carbohydrate transport and metabolism:Lipid transport and metabolism:Transcription:Cell wall/membrane/envelope biogenesis:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:Function unknown:Signal transduction mechanisms:rmlC:Cellular processes and signaling:Information storage and processing:Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides:Cell envelope:Poorly characterized:Metabolism" 87 "Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase:Aspartate/tyrosine/aromatic aminotransferase:FOG: CBS domain:ABC-type dipeptide/oligopeptide/nickel transport systems, permease components:Predicted unusual protein kinase:1-deoxy-D-xylulose 5-phosphate reductoisomerase:Predicted endonuclease involved in recombination (possible Holliday junction resolvase in Mycoplasmas and B. subtilis):Enzyme involved in the deoxyxylulose pathway of isoprenoid biosynthesis:ABC-type dipeptide/oligopeptide/nickel transport systems, permease components:4-diphosphocytidyl-2-methyl-D-erithritol synthase:Predicted transcriptional regulators:Peroxiredoxin:FOG: GGDEF domain:ABC-type oligopeptide transport system, periplasmic component:Uncharacterized protein conserved in bacteria:Amino acid transport and metabolism:Coenzyme transport and metabolism:Lipid transport and metabolism:Transcription:Replication, recombination and repair:Posttranslational modification, protein turnover, chaperones:Inorganic ion transport and metabolism:General function prediction only:Function unknown:Signal transduction mechanisms:Dxr:RNAse_H_YqgF:GGDEF:ispD:ispG_gcpE:ilvE_II:Signal transduction:Other:Biosynthesis of cofactors, prosthetic groups, and carriers:Pyruvate family:Amino acid biosynthesis:General:Unknown function:Metabolism:Poorly characterized:Cellular processes and signaling:Information storage and processing:Other" 88 "Energy production and conversion:ATPase components of ABC transporters with duplicated ATPase domains:ABC-type antimicrobial peptide transport system, permease component:ABC-type multidrug transport system, ATPase component:ABC-type antimicrobial peptide transport system, ATPase component:ABC-type Na+ efflux pump, permease component:Uncharacterized protein conserved in bacteria:ABC-type Na+ transport system, ATPase component:ABC-type transport system, involved in lipoprotein release, permease component:Cell wall/membrane/envelope biogenesis:Inorganic ion transport and metabolism:General function prediction only:Function unknown:Defense mechanisms:Cellular processes and signaling:Poorly characterized:Metabolism" 89 "Predicted hydrolases of the HAD superfamily:Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs:Transcriptional regulator:Predicted transcriptional regulators:Transcriptional regulators:ATPase related to the helicase subunit of the Holliday junction resolvase:Transposase and inactivated derivatives:Predicted transcriptional regulator:Uncharacterized protein conserved in bacteria:Amino acid transport and metabolism:Transcription:Replication, recombination and repair:General function prediction only:Function unknown:Cof-subfamily:Poorly characterized:Metabolism:Information storage and processing:Enzymes of unknown specificity:Unknown function" 90 "Energy production and conversion:Seryl-tRNA synthetase:Thiamine monophosphate synthase:Glycyl-tRNA synthetase (class II):Glycosyltransferase:Methyl-accepting chemotaxis protein:Uncharacterized conserved protein:Transcriptional regulator:Alcohol dehydrogenase, class IV:Cell division protein:Uncharacterized conserved protein:Predicted ATPase involved in cell division:Cell cycle control, cell division, chromosome partitioning:Coenzyme transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:Cell wall/membrane/envelope biogenesis:Cell motility:Function unknown:Signal transduction mechanisms:lytR_cpsA_psr:glyS_dimeric:serS:thiE:FtsE:Protein synthesis:Other:Regulatory functions:Biosynthesis of cofactors, prosthetic groups, and carriers:Metabolism:Cellular processes and signaling:Information storage and processing:Thiamine:Poorly characterized:Cell division:Cellular processes:tRNA aminoacylation" 91 "Energy production and conversion:Thymidine phosphorylase:Acyl carrier protein:Cytidine deaminase:Predicted Zn-dependent proteases and their inactivated homologs:ATP-dependent Zn proteases:NADPH-dependent glutamate synthase beta chain and related oxidoreductases:Biotin carboxyl carrier protein:Signal transduction histidine kinase:Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain:Predicted membrane-associated Zn-dependent proteases 1:3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratases:Phosphopentomutase:Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs:D-alanine-D-alanine ligase and related ATP-grasp enzymes:Mismatch repair ATPase (MutS family):Chromosome segregation ATPases:Uncharacterized conserved protein:Uncharacterized oxidoreductases, Fe-dependent alcohol dehydrogenase family:Uncharacterized protein conserved in bacteria:Uncharacterized protein conserved in bacteria:Superfamily I DNA and RNA helicases:Site-specific recombinase XerD:Cell cycle control, cell division, chromosome partitioning:Amino acid transport and metabolism:Nucleotide transport and metabolism:Carbohydrate transport and metabolism:Lipid transport and metabolism:Transcription:Replication, recombination and repair:Cell wall/membrane/envelope biogenesis:Posttranslational modification, protein turnover, chaperones:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:Function unknown:Signal transduction mechanisms:TIGR00054:IMPACT_YIGZ:acyl_carrier:BCCP:mutS2:FtsH_fam:cyt_deam_tetra:deoB:fabZ:recomb_XerD:Y_phosphoryl:DNA metabolism:Salvage of nucleosides and nucleotides:Other:Purines, pyrimidines, nucleosides, and nucleotides:Biosynthesis:Fatty acid and phospholipid metabolism:Information storage and processing:Poorly characterized:Cellular processes and signaling:Metabolism:General:Unknown function:Degradation of proteins, peptides, and glycopeptides:Protein fate:DNA replication, recombination, and repair:Other" 92 "Energy production and conversion:Glutamate-1-semialdehyde aminotransferase:Uroporphyrinogen-III methylase:Delta-aminolevulinic acid dehydratase:Porphobilinogen deaminase:Diaminopimelate epimerase:Malic enzyme:Glutamyl-tRNA reductase:RecA/RadA recombinase:Nitroreductase:Glutamate racemase:Acylphosphatases:Beta-fructosidases (levanase/invertase):Siroheme synthase (precorrin-2 oxidase/ferrochelatase domain):Pirin-related protein:Tfp pilus assembly protein, pilus retraction ATPase PilT:NTP pyrophosphohydrolases containing a Zn-finger, probably nucleic-acid-binding:Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains:Uncharacterized protein conserved in bacteria:NAD+--asparagine ADP-ribosyltransferase:Amino acid transport and metabolism:Carbohydrate transport and metabolism:Coenzyme transport and metabolism:Transcription:Replication, recombination and repair:Cell wall/membrane/envelope biogenesis:Cell motility:General function prediction only:Function unknown:Signal transduction mechanisms:glut_race:hemC:DapF:hemL:hemA:scrB_fam:pilT_fam:cobA_cysG_Cterm:tigrfam_recA:TIGR02452:prismane_assoc:Intracellular trafficking, secretion, and vesicular transport:Chemotaxis and motility:Metabolism:Poorly characterized:Information storage and processing:Biosynthesis and degradation of murein sacculus and peptidoglycan:Cell envelope:Heme, porphyrin, and cobalamin:Biosynthesis of cofactors, prosthetic groups, and carriers:Aspartate family:Amino acid biosynthesis:Cellular processes and signaling:Cellular processes:DNA replication, recombination, and repair:DNA metabolism:Biosynthesis and degradation of polysaccharides:Electron transport:Energy metabolism" 93 "Uncharacterized membrane protein, putative virulence factor:Chemotaxis signal transduction protein:Membrane protein TerC, possibly involved in tellurium resistance:Flagellar motor component:Flagellin and related hook-associated proteins:Flagellar motor protein:HD-GYP domain:Exopolysaccharide biosynthesis protein:Signal transduction histidine kinase regulating C4-dicarboxylate transport system:Bacterial surface proteins containing Ig-like domains:Cell wall/membrane/envelope biogenesis:Cell motility:Inorganic ion transport and metabolism:General function prediction only:Signal transduction mechanisms:mviN:R_switched_YkoY:Metabolism:Cellular processes and signaling:General:Unknown function:Poorly characterized" 94 "Glycosyltransferase:Nucleoside-diphosphate-sugar epimerases:Phosphoenolpyruvate synthase/pyruvate phosphate dikinase:Chemotaxis protein histidine kinase and related kinases:Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain:Methyl-accepting chemotaxis protein:Tfp pilus assembly protein PilF:Uncharacterized protein conserved in bacteria:Carbohydrate transport and metabolism:Transcription:Cell wall/membrane/envelope biogenesis:Cell motility:Function unknown:Signal transduction mechanisms:Intracellular trafficking, secretion, and vesicular transport:Cellular processes and signaling:Poorly characterized:Metabolism:Information storage and processing" 95 "Undecaprenyl pyrophosphate synthase:Hydrogenase maturation factor:Hydrogenase maturation factor:Hydrogenase maturation factor:Predicted integral membrane protein:Molybdopterin biosynthesis enzymes:Transcriptional regulators of sugar metabolism:Zn-dependent proteases:Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog):ABC-type uncharacterized transport systems, ATPase components:Protein involved in polysaccharide intercellular adhesin (PIA) synthesis/biofilm formation:ABC-type uncharacterized transport system, permease component:Carbohydrate transport and metabolism:Coenzyme transport and metabolism:Lipid transport and metabolism:Transcription:Posttranslational modification, protein turnover, chaperones:General function prediction only:Function unknown:Signal transduction mechanisms:hypC_hupF:hypF:molyb_syn:TIGR00374:hypE:spo_ytxC:spore_YyaC:Sporulation and germination:Cellular processes:Protein modification and repair:Protein fate:Metabolism:Poorly characterized:Cellular processes and signaling:Information storage and processing:Conserved:Hypothetical proteins" 96 "Nucleoside-diphosphate-sugar epimerases:Glycosyltransferases involved in cell wall biogenesis:Predicted glycosyltransferases:Flagellar motor component:Flagellin and related hook-associated proteins:Flagellar motor protein:Flagellar hook protein FlgE:Lysophospholipase L1 and related esterases:Flagellar hook-length control protein:Amino acid transport and metabolism:Carbohydrate transport and metabolism:Cell wall/membrane/envelope biogenesis:Cell motility:General function prediction only:FlgEFG_subfam:Poorly characterized:Metabolism:Cellular processes and signaling" 97 "Energy production and conversion:3-oxoacyl-(acyl-carrier-protein) synthase:3-oxoacyl-[acyl-carrier-protein] synthase III:ABC-type Fe3+-hydroxamate transport system, periplasmic component:Multimeric flavodoxin WrbA:Predicted thioesterase:Enoyl-CoA hydratase/carnithine racemase:Fe-S oxidoreductase:ABC-type antimicrobial peptide transport system, ATPase component:3-hydroxyacyl-CoA dehydrogenase:Glycosyl transferases, related to UDP-glucuronosyltransferase:Phosphopantetheinyl transferase:Molybdenum cofactor biosynthesis enzyme:Indolepyruvate ferredoxin oxidoreductase, alpha and beta subunits:ABC-type transport system, involved in lipoprotein release, permease component:Uncharacterized protein containing a NRPS condensation (elongation) domain:Carbohydrate transport and metabolism:Coenzyme transport and metabolism:Lipid transport and metabolism:Cell wall/membrane/envelope biogenesis:Inorganic ion transport and metabolism:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:MGT:moaA:IOR_alpha:Defense mechanisms:Cellular processes and signaling:Molybdopterin:Poorly characterized:Toxin production and resistance:Cellular processes:Biosynthesis of cofactors, prosthetic groups, and carriers:Metabolism" 98 "Energy production and conversion:3-methyladenine DNA glycosylase/8-oxoguanine DNA glycosylase:Superfamily I DNA and RNA helicases:Nitrogen regulatory protein PII:Sugar kinases, ribokinase family:UDP-N-acetylglucosamine enolpyruvyl transferase:Sugar phosphate isomerases/epimerases:dTDP-D-glucose 4,6-dehydratase:ABC-type multidrug transport system, ATPase component:ABC-type antimicrobial peptide transport system, ATPase component:Chromosome segregation ATPases:Nitrogenase subunit NifH (ATPase):Predicted membrane protein:Beta-fructosidases (levanase/invertase):Nitrogenase molybdenum-iron protein, alpha and beta chains:ABC-type transport system, involved in lipoprotein release, permease component:Glycopeptide antibiotics resistance protein:Predicted multitransmembrane protein:Cell cycle control, cell division, chromosome partitioning:Amino acid transport and metabolism:Carbohydrate transport and metabolism:Replication, recombination and repair:Cell wall/membrane/envelope biogenesis:Inorganic ion transport and metabolism:Function unknown:efflux_EmrB:murA:pcrA:nifD:nifH:Defense mechanisms:Transport and binding proteins:Cellular processes and signaling:Metabolism:Poorly characterized:Biosynthesis and degradation of murein sacculus and peptidoglycan:Cell envelope:Other:Information storage and processing:DNA replication, recombination, and repair:DNA metabolism:Nitrogen fixation:Central intermediary metabolism" 99 "Integral membrane protein possibly involved in chromosome condensation:Aspartate/tyrosine/aromatic aminotransferase:Phosphatidylglycerophosphate synthase:Single-stranded DNA-binding protein:DNA polymerase I - 3'-5' exonuclease and polymerase domains:DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog:Uncharacterized distant relative of cell wall-associated hydrolases:Uncharacterized protein related to glutamine synthetase:Signal transduction histidine kinase:Cell cycle control, cell division, chromosome partitioning:Amino acid transport and metabolism:Lipid transport and metabolism:Transcription:Replication, recombination and repair:General function prediction only:Function unknown:Signal transduction mechanisms:crcB:pgsA:pola:ssb:sigma70-ECF:Biosynthesis:Fatty acid and phospholipid metabolism:Unknown function:Metabolism:Cellular processes and signaling:Information storage and processing:General:Poorly characterized:DNA replication, recombination, and repair:DNA metabolism" 100 "Energy production and conversion:Acetyltransferase (isoleucine patch superfamily):Thymidylate synthase:Asparagine synthase (glutamine-hydrolyzing):Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis:Glycosyltransferases involved in cell wall biogenesis:ATP-dependent Lon protease, bacterial type:Predicted GTPase:Zn-dependent hydrolases, including glyoxylases:Preprotein translocase subunit SecA (ATPase, RNA helicase):Methyl-accepting chemotaxis protein:Predicted nucleotide-utilizing enzyme related to molybdopterin-biosynthesis enzyme MoeA:Galactose-1-phosphate uridylyltransferase:Methylase of chemotaxis methyl-accepting proteins:Predicted transcriptional regulators:Conserved protein/domain typically associated with flavoprotein oxygenases, DIM6/NTAB family:Uncharacterized oxidoreductases, Fe-dependent alcohol dehydrogenase family:Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain:Uncharacterized protein conserved in bacteria:Signal transduction histidine kinase:Endopolygalacturonase:Amino acid transport and metabolism:Nucleotide transport and metabolism:Carbohydrate transport and metabolism:Transcription:Cell wall/membrane/envelope biogenesis:Cell motility:Posttranslational modification, protein turnover, chaperones:General function prediction only:Signal transduction mechanisms:molyb_syn:galT_1:sensory_box:small_GTP:lon:secA:asn_synth_AEB:thym_sym:Intracellular trafficking, secretion, and vesicular transport:Unknown function:Degradation of proteins, peptides, and glycopeptides:Protein and peptide secretion and trafficking:Protein fate:Small molecule interactions:Regulatory functions:2'-Deoxyribonucleotide metabolism:Purines, pyrimidines, nucleosides, and nucleotides:Sugars:Energy metabolism:General:Amino acid biosynthesis:Aspartate family:Information storage and processing:Cellular processes and signaling:Metabolism:Poorly characterized" 101 "Site-specific DNA methylase:DNA polymerase III, alpha subunit:Phosphoglycerate mutase 1:Single-stranded DNA-binding protein:Signal transduction histidine kinase:Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain:ABC-type antimicrobial peptide transport system, ATPase component:Uncharacterized protein conserved in bacteria:Retron-type reverse transcriptase:Uncharacterized protein conserved in bacteria:Carbohydrate transport and metabolism:Transcription:Replication, recombination and repair:Function unknown:Signal transduction mechanisms:polc:ssb:dcm:pgm_1:Defense mechanisms:Information storage and processing:Poorly characterized:DNA metabolism:DNA replication, recombination, and repair:Metabolism:Cellular processes and signaling" 102 "Predicted GTPase:Putative translation initiation inhibitor, yjgF family:Lactoylglutathione lyase and related lyases:FOG: Ankyrin repeat:Predicted Rossmann fold nucleotide-binding protein involved in DNA uptake:ABC-type multidrug transport system, ATPase and permease components:ABC-type metal ion transport system, ATPase component:Flagellar motor component:Methionine synthase I, cobalamin-binding domain:Predicted P-loop-containing kinase:D-alanyl-D-alanine carboxypeptidase:FOG: FHA domain:Site-specific recombinases, DNA invertase Pin homologs:Predicted transcriptional regulator:Sporulation protein and related proteins:Uncharacterized conserved protein:Signal transduction histidine kinase:Cell cycle control, cell division, chromosome partitioning:Amino acid transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:Replication, recombination and repair:Cell wall/membrane/envelope biogenesis:Cell motility:Inorganic ion transport and metabolism:General function prediction only:Function unknown:Signal transduction mechanisms:dprA:metH:SpoIID_LytB:GTPase_YsxC:Intracellular trafficking, secretion, and vesicular transport:Defense mechanisms:Information storage and processing:Aspartate family:Amino acid biosynthesis:General:Unknown function:Cellular processes and signaling:Cellular processes:Other:Protein synthesis:Metabolism:Poorly characterized:DNA transformation" 103 "Energy production and conversion:ATPase components of ABC transporters with duplicated ATPase domains:rRNA methylases:ABC-type antimicrobial peptide transport system, permease component:Phosphate uptake regulator:ABC-type phosphate transport system, ATPase component:ABC-type multidrug transport system, ATPase component:ABC-type antimicrobial peptide transport system, ATPase component:ABC-type Na+ efflux pump, permease component:Uncharacterized protein conserved in bacteria:Predicted RNA-binding protein containing a PIN domain:ABC-type transport system, involved in lipoprotein release, permease component:Translation, ribosomal structure and biogenesis:Cell wall/membrane/envelope biogenesis:Inorganic ion transport and metabolism:General function prediction only:Function unknown:rRNA_methyl_3:3a0107s01c2:phoU_full:Defense mechanisms:Information storage and processing:Anions:Transport and binding proteins:tRNA and rRNA base modification:Protein synthesis:Cellular processes and signaling:Metabolism:Poorly characterized" 104 "3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase and related enzymes:Guanylate kinase:DNA-directed RNA polymerase specialized sigma subunit:Chromosome segregation ATPases:Cell cycle control, cell division, chromosome partitioning:Amino acid transport and metabolism:Nucleotide transport and metabolism:Coenzyme transport and metabolism:Transcription:tape_meas_TP901:sigma70-ECF:Metabolism:Information storage and processing:Prophage functions:Mobile and extrachromosomal element functions:Cellular processes and signaling" 105 "Energy production and conversion:Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), B subunit:Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), A subunit:Peptidyl-tRNA hydrolase:Glycosyltransferase:Cation transport ATPase:FOG: CBS domain:Predicted Zn-dependent peptidases:Predicted Zn-dependent peptidases, insulinase-like:Fe-S oxidoreductase:Transglutaminase-like enzymes, putative cysteine proteases:Uncharacterized protein, involved in the regulation of septum location:Transcriptional accessory protein:Uncharacterized conserved protein:Uncharacterized conserved protein:Exopolysaccharide biosynthesis protein related to N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase:Predicted membrane protein:Amino acid transport and metabolism:Carbohydrate transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:Replication, recombination and repair:Cell wall/membrane/envelope biogenesis:Inorganic ion transport and metabolism:General function prediction only:Function unknown:pth:YaaA_near_RecF:Metabolism:Cellular processes and signaling:Information storage and processing:Other:Protein synthesis:DNA replication, recombination, and repair:DNA metabolism:Poorly characterized" 106 "Adenylosuccinate lyase:Pseudouridylate synthase:Superfamily II DNA and RNA helicases:Mg2+ and Co2+ transporters:ABC-type cobalt transport system, permease component CbiQ and related transporters:Predicted permease:Coproporphyrinogen III oxidase and related Fe-S oxidoreductases:Signal peptidase I:MoxR-like ATPases:ABC-type amino acid transport/signal transduction systems, periplasmic component/domain:ABC-type multidrug transport system, permease component:ABC-type polar amino acid transport system, ATPase component:Disulfide bond chaperones of the HSP33 family:Precorrin-6B methylase 1:Uncharacterized conserved protein:Uncharacterized conserved protein:Uncharacterized protein related to glutamine synthetase:Signal transduction histidine kinase:Amino acid transport and metabolism:Nucleotide transport and metabolism:Coenzyme transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:Replication, recombination and repair:Posttranslational modification, protein turnover, chaperones:Inorganic ion transport and metabolism:General function prediction only:Function unknown:Signal transduction mechanisms:hisT_truA:corA:hemN_rel:purB:HEQRo_perm_3TM:sigpep_I_bact:CbiE:Intracellular trafficking, secretion, and vesicular transport:Defense mechanisms:Cations and iron carrying compounds:Amino acids, peptides and amines:Transport and binding proteins:Protein and peptide secretion and trafficking:Protein fate:tRNA and rRNA base modification:Protein synthesis:Biosynthesis of cofactors, prosthetic groups, and carriers:Purines, pyrimidines, nucleosides, and nucleotides:Heme, porphyrin, and cobalamin:Information storage and processing:Cellular processes and signaling:Metabolism:Poorly characterized:Purine ribonucleotide biosynthesis" 107 "Glycosyltransferases involved in cell wall biogenesis:Chemotaxis protein histidine kinase and related kinases:FOG: CheY-like receiver:Methyl-accepting chemotaxis protein:Predicted glycosyltransferases:Sialic acid synthase:HD-GYP domain:Spore coat polysaccharide biosynthesis protein, predicted glycosyltransferase:Bacterial surface proteins containing Ig-like domains:Predicted integral membrane protein:Cell wall/membrane/envelope biogenesis:Cell motility:General function prediction only:Function unknown:Signal transduction mechanisms:exosort_Gpos:PseI:PseG:Cellular processes and signaling:Poorly characterized" 108 "ABC-type sugar transport system, permease component:Zn-dependent hydrolases, including glyoxylases:Multimeric flavodoxin WrbA:Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain:2-keto-3-deoxy-6-phosphogluconate aldolase:Metal-dependent amidase/aminoacylase/carboxypeptidase:Uracil-DNA glycosylase:Predicted transcriptional regulators:Pirin-related protein:Phospholipid-binding protein:Regulators of stationary/sporulation gene expression:Cation transport ATPase:Predicted phosphosugar isomerases:Membrane protein involved in the export of O-antigen and teichoic acid:Cyanate permease:NTP pyrophosphohydrolases containing a Zn-finger, probably nucleic-acid-binding:Regulator of cell morphogenesis and NO signaling:Short-chain dehydrogenase involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein):Cell cycle control, cell division, chromosome partitioning:Carbohydrate transport and metabolism:Transcription:Replication, recombination and repair:Cell wall/membrane/envelope biogenesis:Inorganic ion transport and metabolism:General function prediction only:Signal transduction mechanisms:TIGR00003:TIGR00481:efflux_EmrB:UDG_fam4:eda:lp_hng_hel_AbrB:amidohydrolases:spore_V_B:FeS_repair_RIC:Metabolism:Cellular processes and signaling:Information storage and processing:Other:Biosynthesis of cofactors, prosthetic groups, and carriers:General:Unknown function:Sporulation and germination:Cellular processes:Other:Poorly characterized:Transport and binding proteins:Degradation of proteins, peptides, and glycopeptides:Protein fate:DNA replication, recombination, and repair:DNA metabolism:DNA interactions:Regulatory functions:Entner-Doudoroff:Energy metabolism:Cations and iron carrying compounds" 109 "Energy production and conversion:Acetyl-CoA acetyltransferase:Ribosomal protein L7/L12:Phosphoribosylpyrophosphate synthetase:Signal transduction histidine kinase:Predicted xylanase/chitin deacetylase:DNA polymerase I - 3'-5' exonuclease and polymerase domains:Transcription elongation factor:Aspartate ammonia-lyase:Lactate dehydrogenase and related dehydrogenases:Predicted GTPases:Transcriptional regulators of sugar metabolism:Predicted alternative thymidylate synthase:DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog:Uncharacterized protein conserved in bacteria:Conserved protein/domain typically associated with flavoprotein oxygenases, DIM6/NTAB family:HD-GYP domain:Gamma-glutamylcysteine synthetase:Uncharacterized protein conserved in bacteria:Uncharacterized conserved small protein:Amino acid transport and metabolism:Nucleotide transport and metabolism:Carbohydrate transport and metabolism:Coenzyme transport and metabolism:Lipid transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:Replication, recombination and repair:General function prediction only:Function unknown:Signal transduction mechanisms:small_GTP:pola:ribP_PPkin:glu_cys_ligase:greA:AcCoA-C-Actrans:spore_sigH:General:Unknown function:Sporulation and germination:Cellular processes:Transcription factors:Transcription:DNA replication, recombination, and repair:DNA metabolism:Purine ribonucleotide biosynthesis:Purines, pyrimidines, nucleosides, and nucleotides:Other:Fatty acid and phospholipid metabolism:Metabolism:Poorly characterized:Cellular processes and signaling:Information storage and processing:Glutathione and analogs:Biosynthesis of cofactors, prosthetic groups, and carriers" 110 "Spermidine synthase:Acetyltransferases:Carbamoylphosphate synthase large subunit (split gene in MJ):Carbamoylphosphate synthase small subunit:Uncharacterized conserved protein:Putative protein-S-isoprenylcysteine methyltransferase:Putative peptidoglycan-binding domain-containing protein:Bacterial surface proteins containing Ig-like domains:Predicted secreted protein:Amino acid transport and metabolism:Nucleotide transport and metabolism:Cell wall/membrane/envelope biogenesis:Cell motility:Posttranslational modification, protein turnover, chaperones:General function prediction only:Function unknown:speE:CPSaseIIsmall:CPSaseII_lrg:spore_V_AC:Polyamine biosynthesis:Central intermediary metabolism:Cellular processes:Metabolism:Cellular processes and signaling:Sporulation and germination:Poorly characterized:Pyrimidine ribonucleotide biosynthesis:Purines, pyrimidines, nucleosides, and nucleotides" 111 "Energy production and conversion:4-aminobutyrate aminotransferase and related aminotransferases:Phosphate uptake regulator:Amino acid transporters:ABC-type antimicrobial peptide transport system, ATPase component:N-Dimethylarginine dimethylaminohydrolase:Dissimilatory sulfite reductase (desulfoviridin), alpha and beta subunits:Endoglucanase:Ethanolamine ammonia-lyase, large subunit:NAD+--asparagine ADP-ribosyltransferase:Amino acid transport and metabolism:Carbohydrate transport and metabolism:Inorganic ion transport and metabolism:Signal transduction mechanisms:GABAtrnsam:2A0305:phoU_full:sulfite_red_C:Defense mechanisms:Amino acids, peptides and amines:Transport and binding proteins:Metabolism:Other:Central intermediary metabolism:Sulfur metabolism:Cellular processes and signaling:Anions" 112 "Acetylglutamate semialdehyde dehydrogenase:Ornithine carbamoyltransferase:Argininosuccinate synthase:Argininosuccinate lyase:ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component:Acetylglutamate kinase:ABC-type dipeptide/oligopeptide/nickel transport systems, permease components:ABC-type dipeptide transport system, periplasmic component:ABC-type amino acid transport/signal transduction systems, periplasmic component/domain:N-acetylglutamate synthase (N-acetylornithine aminotransferase):Transcriptional regulator/sugar kinase:Ornithine/acetylornithine aminotransferase:Amino acid transport and metabolism:Carbohydrate transport and metabolism:Transcription:Inorganic ion transport and metabolism:Signal transduction mechanisms:argG:ArgJ:orni_carb_tr:argD:argB:argH:oligo_HPY:argC:Cellular processes and signaling:Metabolism:Information storage and processing:Glutamate family:Amino acid biosynthesis:Amino acids, peptides and amines:Transport and binding proteins" 113 "Predicted amidohydrolase:Uncharacterized conserved protein:Aspartate/tyrosine/aromatic aminotransferase:Superfamily II DNA helicase:Predicted dehydrogenases and related proteins:Predicted permeases:Methyl-accepting chemotaxis protein:Uncharacterized protein conserved in bacteria:Predicted membrane protein:Uncharacterized conserved protein:Zn-ribbon protein, possibly nucleic acid-binding:Acetyltransferases, including N-acetylases of ribosomal proteins:Transcriptional regulators:Uncharacterized conserved protein, contains double-stranded beta-helix domain:Fe2+ transport system protein A:Predicted metal-dependent hydrolases related to alanyl-tRNA synthetase HxxxH domain:Predicted membrane protein:Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains:Uncharacterized protein involved in tellurite resistance:Predicted membrane protein:Amino acid transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:Replication, recombination and repair:Cell motility:Inorganic ion transport and metabolism:General function prediction only:Function unknown:Signal transduction mechanisms:TIGR00149_YbjQ:sensory_box:tRNA_RlmH_YbeA:recQ_fam:T7_esaA_Nterm:TIGR03943:Unknown function:tRNA and rRNA base modification:Protein synthesis:DNA replication, recombination, and repair:DNA metabolism:Small molecule interactions:Regulatory functions:Metabolism:Poorly characterized:Cellular processes and signaling:Information storage and processing:Enzymes of unknown specificity" 114 "Energy production and conversion:Isopropylmalate/homocitrate/citramalate synthases:Ribosomal protein L9:Asparagine synthase (glutamine-hydrolyzing):Isocitrate/isopropylmalate dehydrogenase:FOG: CBS domain:Mannose-1-phosphate guanylyltransferase:Membrane-fusion protein:Aconitase A:Predicted ATP-dependent protease:ABC-type multidrug transport system, ATPase component:ABC-type transport system involved in multi-copper enzyme maturation, permease component:Mn-dependent transcriptional regulator:Rubrerythrin:Uncharacterized conserved protein:Mn-containing catalase:Uncharacterized protein conserved in bacteria:Predicted glycosyl hydrolase:Uncharacterized protein conserved in bacteria:Amino acid transport and metabolism:Carbohydrate transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:Cell wall/membrane/envelope biogenesis:Posttranslational modification, protein turnover, chaperones:Inorganic ion transport and metabolism:General function prediction only:Function unknown:L9:mito_nad_idh:acon_putative:asn_synth_AEB:spore_lon_C:Defense mechanisms:Aspartate family:Amino acid biosynthesis:Sporulation and germination:Cellular processes:Poorly characterized:Protein synthesis:TCA cycle:Energy metabolism:Ribosomal proteins: synthesis and modification:Metabolism:Cellular processes and signaling:Information storage and processing" 115 "Amino acid transporters:Transcriptional regulator:Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain:ABC-type multidrug transport system, permease component:ABC-type multidrug transport system, ATPase component:ABC-type antimicrobial peptide transport system, ATPase component:Amidases related to nicotinamidase:Uncharacterized conserved protein:Membrane protein involved in the export of O-antigen and teichoic acid:Predicted membrane protein:Sortase (surface protein transpeptidase):Uncharacterized protein conserved in bacteria:Uncharacterized protein conserved in bacteria:Uncharacterized conserved protein:Amino acid transport and metabolism:Transcription:Cell wall/membrane/envelope biogenesis:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:Function unknown:Signal transduction mechanisms:2A0309:sortase_fam:TIGR03943:Defense mechanisms:Cellular processes and signaling:Information storage and processing:Amino acids, peptides and amines:Poorly characterized:Protein and peptide secretion and trafficking:Protein fate:Transport and binding proteins:Metabolism" 116 "Energy production and conversion:Ribosomal protein S10:Ribosomal protein L11:Ribosomal protein L23:Ribonuclease HII:Dihydroorotate dehydrogenase:Ribosomal protein L10:Transcription antiterminator:Orotidine-5'-phosphate decarboxylase:Aspartate carbamoyltransferase, catalytic chain:2-polyprenylphenol hydroxylase and related flavodoxin oxidoreductases:Preprotein translocase subunit SecE:Predicted transcriptional regulators:Predicted GTPases:Predicted oxidoreductases of the aldo/keto reductase family:Putative transcriptional regulator, homolog of Bvg accessory factor:Aspartate carbamoyltransferase, regulatory subunit:Pyrimidine operon attenuation protein/uracil phosphoribosyltransferase:Xanthine/uracil permeases:Nucleotide transport and metabolism:Coenzyme transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:Replication, recombination and repair:General function prediction only:asp_carb_tr:baf:ncs2:nusG:secE_bact:pyrD_sub1_fam:rpsJ_bact:L11_bact:pyrF_sub2:GTPase_YlqF:Intracellular trafficking, secretion, and vesicular transport:Information storage and processing:Pantothenate and coenzyme A:Biosynthesis of cofactors, prosthetic groups, and carriers:Nucleosides, purines and pyrimidines:Transport and binding proteins:Protein and peptide secretion and trafficking:Protein fate:Ribosomal proteins: synthesis and modification:Other:Protein synthesis:Transcription factors:Transcription:Pyrimidine ribonucleotide biosynthesis:Purines, pyrimidines, nucleosides, and nucleotides:Cellular processes and signaling:Metabolism:Poorly characterized" 117 "Energy production and conversion:Glycosyltransferase:Cell division protein FtsI/penicillin-binding protein 2:Lactate dehydrogenase and related dehydrogenases:Uncharacterized protein conserved in bacteria:Predicted membrane protein:AraC-type DNA-binding domain-containing proteins:Precorrin-6B methylase 1:ATP-dependent transcriptional regulator:Predicted transcriptional regulator:Cobalamin biosynthesis protein CbiK, Co2+ chelatase:Coenzyme transport and metabolism:Transcription:Cell wall/membrane/envelope biogenesis:General function prediction only:Function unknown:CbiE:Poorly characterized:Metabolism:Cellular processes and signaling:Information storage and processing" 118 "Predicted integral membrane protein:Glycosyltransferases involved in cell wall biogenesis:ABC-type phosphate transport system, permease component:ABC-type phosphate transport system, permease component:ABC-type multidrug transport system, permease component:Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases):Phosphomannomutase:Subtilisin-like serine proteases:Membrane protein involved in the export of O-antigen and teichoic acid:Lysophospholipase:Uncharacterized FAD-dependent dehydrogenases:Cellobiose phosphorylase:Cell wall hydrolyses involved in spore germination:Uncharacterized conserved protein:Endopolygalacturonase:Carbohydrate transport and metabolism:Lipid transport and metabolism:Cell wall/membrane/envelope biogenesis:Posttranslational modification, protein turnover, chaperones:Inorganic ion transport and metabolism:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:Function unknown:TIGR00374:3a0107s02c:phosphate_pstC:spore_V_AC:spore_V_AE:spore_SleB:Defense mechanisms:Sporulation and germination:Cellular processes:Poorly characterized:Transport and binding proteins:Anions:Metabolism:Cellular processes and signaling:Conserved:Hypothetical proteins" 119 "Carbamoylphosphate synthase large subunit (split gene in MJ):Metal-dependent amidase/aminoacylase/carboxypeptidase:Amino acid transport and metabolism:Nucleotide transport and metabolism:General function prediction only:amidohydrolases:Poorly characterized:Metabolism:Degradation of proteins, peptides, and glycopeptides:Protein fate" 120 "NAD/FAD-utilizing enzyme apparently involved in cell division:FOG: CheY-like receiver:Adenine-specific DNA methylase:N-acetylglutamate synthase and related acetyltransferases:Spore coat polysaccharide biosynthesis protein F, CMP-KDO synthetase homolog:Uncharacterized protein conserved in bacteria:Uncharacterized protein conserved in bacteria:ABC-type oligopeptide transport system, ATPase component:Predicted oxidoreductase:Cell cycle control, cell division, chromosome partitioning:Amino acid transport and metabolism:Replication, recombination and repair:Cell wall/membrane/envelope biogenesis:General function prediction only:Function unknown:Signal transduction mechanisms:gidA:oligo_HPY:Metabolism:Cellular processes and signaling:Information storage and processing:Amino acids, peptides and amines:Transport and binding proteins:tRNA and rRNA base modification:Protein synthesis:Poorly characterized" 121 "Phage terminase, small subunit:Lyzozyme M1 (1,4-beta-N-acetylmuramidase):Phage-related tail protein:Bacteriophage head-tail adaptor:Replication, recombination and repair:Cell wall/membrane/envelope biogenesis:General function prediction only:Function unknown:sm_term_P27:put_DNA_pack:gp16_SPP1:maj_tail_phi13:put_anti_recept:phge_HK97_gp10:tape_meas_TP901:Information storage and processing:Mobile and extrachromosomal element functions:Prophage functions:Poorly characterized:Cellular processes and signaling" 122 "Energy production and conversion:Methyl-accepting chemotaxis protein:Flagellar biosynthesis pathway, component FlhA:Flagellar biosynthesis pathway, component FliP:Flagellin and related hook-associated proteins:Flagellar biosynthesis pathway, component FlhB:Predicted transcriptional regulators:Chemotaxis protein CheC, inhibitor of MCP methylation:NADH:flavin oxidoreductases, Old Yellow Enzyme family:Sialic acid synthase:HD-GYP domain:Tfp pilus assembly protein PilF:Flagellar biogenesis protein:Fucose 4-O-acetylase and related acetyltransferases:Exopolysaccharide biosynthesis protein:Bacterial surface proteins containing Ig-like domains:Carbohydrate transport and metabolism:Transcription:Cell wall/membrane/envelope biogenesis:Cell motility:Signal transduction mechanisms:parB_part:flhB:fliP:FlhA:fliN:FliO_TIGR:PseI:Intracellular trafficking, secretion, and vesicular transport:Cellular processes:Chemotaxis and motility:Information storage and processing:Cellular processes and signaling:Metabolism" 123 "Predicted GTPase:Acetyltransferases:Uncharacterized ABC-type transport system, permease component:Phosphomannomutase:ABC-type multidrug transport system, ATPase and permease components:Flagellar motor component:Flagellar motor protein:Uncharacterized conserved protein:FOG: EAL domain:Signal transduction histidine kinase:Uncharacterized conserved protein:Carbohydrate transport and metabolism:Cell motility:General function prediction only:Function unknown:Signal transduction mechanisms:GGDEF:GTPase_YsxC:Defense mechanisms:Metabolism:Cellular processes and signaling:Other:Poorly characterized:Other:Protein synthesis:Signal transduction" 124 "FOG: CheY-like receiver:ABC-type multidrug transport system, ATPase component:ABC-type antimicrobial peptide transport system, ATPase component:UDP-glucose pyrophosphorylase:Transcriptional regulator:Acetyltransferases, including N-acetylases of ribosomal proteins:Phosphotransferase system mannitol/fructose-specific IIA domain (Ntr-type):Transcriptional regulators:Uncharacterized protein conserved in bacteria:Ethanolamine ammonia-lyase, small subunit:Amino acid transport and metabolism:Carbohydrate transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:Cell wall/membrane/envelope biogenesis:Function unknown:Signal transduction mechanisms:galU:Defense mechanisms:Poorly characterized:Metabolism:Cellular processes and signaling:Information storage and processing:Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides:Cell envelope" 125 "Acetyltransferase (isoleucine patch superfamily):Ribose 5-phosphate isomerase:Site-specific DNA methylase:Hydrogenase maturation factor:Predicted xylanase/chitin deacetylase:Polyphosphate kinase:Predicted Fe-S oxidoreductase:Predicted phosphohydrolases:Uncharacterized protein conserved in bacteria:Arabinose efflux permease:Phosphotransferase system, mannose/fructose-specific component IIA:Uncharacterized conserved protein:Carbohydrate transport and metabolism:Replication, recombination and repair:Posttranslational modification, protein turnover, chaperones:Inorganic ion transport and metabolism:General function prediction only:Function unknown:rpiA:hypD:dam:TIGR01212:poly_P_kin:Enzymes of unknown specificity:Unknown function:Protein modification and repair:Protein fate:DNA replication, recombination, and repair:Poorly characterized:Pentose phosphate pathway:Energy metabolism:Phosphorus compounds:Central intermediary metabolism:DNA metabolism:Metabolism:Cellular processes and signaling:Information storage and processing" 126 "Flagellar biosynthesis/type III secretory pathway ATPase:Flagellar biosynthesis/type III secretory pathway protein:Flagellar motor switch protein:Flagellar basal body rod protein:Uncharacterized protein, possibly involved in motility:Flagellar hook-basal body protein:Flagellar biosynthesis/type III secretory pathway lipoprotein:Flagellar basal body protein:Flagellar hook capping protein:Cell division protein:Flagellar biosynthesis chaperone:Predicted ATPase involved in cell division:Flagellar hook-length control protein:Uncharacterized protein involved in tellurite resistance:Uncharacterized protein involved in stress response:Cell cycle control, cell division, chromosome partitioning:Cell motility:Posttranslational modification, protein turnover, chaperones:Inorganic ion transport and metabolism:General function prediction only:fliE:fliF:fliG:fliI_yscN:FlgC:FlgB:flagell_FliJ:FtsE:Intracellular trafficking, secretion, and vesicular transport:Energy metabolism:ATP-proton motive force interconversion:Cellular processes:Cell division:Chemotaxis and motility:Cellular processes and signaling:Metabolism:Poorly characterized" 127 "Energy production and conversion:Isopropylmalate/homocitrate/citramalate synthases:Ribose 5-phosphate isomerase:Isocitrate/isopropylmalate dehydrogenase:Membrane-associated phospholipid phosphatase:Mannose-1-phosphate guanylyltransferase:Aconitase A:Predicted ATP-dependent protease:ABC-type multidrug transport system, ATPase component:Mn-dependent transcriptional regulator:Rubrerythrin:Uncharacterized conserved protein:3-methyladenine DNA glycosylase:Mn-containing catalase:Predicted glycosyl hydrolase:Amino acid transport and metabolism:Carbohydrate transport and metabolism:Lipid transport and metabolism:Transcription:Replication, recombination and repair:Cell wall/membrane/envelope biogenesis:Posttranslational modification, protein turnover, chaperones:Inorganic ion transport and metabolism:General function prediction only:Function unknown:rpiA:mito_nad_idh:HDIG:3mg:acon_putative:autotrns_rpt:Defense mechanisms:Cellular processes:DNA replication, recombination, and repair:DNA metabolism:TCA cycle:Pentose phosphate pathway:Energy metabolism:Pathogenesis:Information storage and processing:Cellular processes and signaling:Metabolism:Poorly characterized" 128 "Ketol-acid reductoisomerase:Enolase:Triosephosphate isomerase:DnaJ-class molecular chaperone with C-terminal Zn finger domain:Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases:Molecular chaperone GrpE (heat shock protein):Aldo/keto reductases, related to diketogulonate reductase:Fe2+/Zn2+ uptake regulation proteins:Protease subunit of ATP-dependent Clp proteases:FOG: CheY-like receiver:UDP-glucose 4-epimerase:UDP-glucose pyrophosphorylase:ATP-dependent protease Clp, ATPase subunit:Predicted HD superfamily hydrolase:Transcriptional regulator of heat shock gene:Ribosome-associated protein Y (PSrp-1):Uncharacterized conserved protein (small basic protein):Uncharacterized protein conserved in bacteria:Uncharacterized protein conserved in bacteria:Amino acid transport and metabolism:Nucleotide transport and metabolism:Carbohydrate transport and metabolism:Coenzyme transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:Cell wall/membrane/envelope biogenesis:Posttranslational modification, protein turnover, chaperones:Inorganic ion transport and metabolism:General function prediction only:Function unknown:Signal transduction mechanisms:S21p:HDIG:hrcA:clpX:tim:ilvC:clpP:yfiA:eno:galU:DnaJ_bact:spore_0_A:Intracellular trafficking, secretion, and vesicular transport:Translation factors:Ribosomal proteins: synthesis and modification:Protein synthesis:DNA interactions:Regulatory functions:Glycolysis/gluconeogenesis:Energy metabolism:Poorly characterized:Pyruvate family:Metabolism:Cellular processes and signaling:Amino acid biosynthesis:Sporulation and germination:Cellular processes:Degradation of proteins, peptides, and glycopeptides:Information storage and processing:Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides:Cell envelope:Protein fate" 129 "Serine/threonine protein phosphatase:Multimeric flavodoxin WrbA:DNA segregation ATPase FtsK/SpoIIIE and related proteins:Uncharacterized conserved protein:Uncharacterized protein conserved in bacteria:Cell cycle control, cell division, chromosome partitioning:General function prediction only:Function unknown:Signal transduction mechanisms:T7_EssCb_Firm:WXG100_ESAT6:Poorly characterized:Cellular processes and signaling:Protein and peptide secretion and trafficking:Protein fate" 130 "Predicted membrane protein:Glycosyltransferase:UDP-N-acetylmuramyl tripeptide synthase:Cell wall-associated hydrolases (invasion-associated proteins):Predicted glycosyltransferases:Predicted transcriptional regulator, consists of a Zn-ribbon and ATP-cone domains:Amidases related to nicotinamidase:ATP-utilizing enzymes of the PP-loop superfamily:Predicted redox protein, regulator of disulfide bond formation:Membrane protein involved in the export of O-antigen and teichoic acid:Predicted acetyltransferase:Iron only hydrogenase large subunit, C-terminal domain:Bacterial surface proteins containing Ig-like domains:Transcription:Cell wall/membrane/envelope biogenesis:Cell motility:Posttranslational modification, protein turnover, chaperones:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:Function unknown:TIGR00023:TIGR00244:TIGR00268:HDIG:murE:FeFe_hydrog_A:Fatty acid and phospholipid metabolism:Cell envelope:Metabolism:Poorly characterized:Information storage and processing:Biosynthesis and degradation of murein sacculus and peptidoglycan:Cellular processes and signaling:Conserved:Hypothetical proteins:DNA interactions:Regulatory functions:Biosynthesis" 131 "Energy production and conversion:Predicted hydrolases of the HAD superfamily:Signal transduction histidine kinase:Cellulase M and related proteins:NADH:flavin oxidoreductases, Old Yellow Enzyme family:Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain:Uncharacterized protein conserved in bacteria:Carbohydrate transport and metabolism:Transcription:General function prediction only:Function unknown:Signal transduction mechanisms:Cof-subfamily:WXG100_ESAT6:Cellular processes and signaling:Information storage and processing:Metabolism:Unknown function:Poorly characterized:Enzymes of unknown specificity" 132 "Short-chain dehydrogenases of various substrate specificities:Biotin-(acetyl-CoA carboxylase) ligase:Predicted metal-dependent phosphoesterases (PHP family):ABC-type cobalt transport system, permease component CbiQ and related transporters:Signal transduction histidine kinase:Type II restriction enzyme, methylase subunits:Transcriptional regulator:DNA repair photolyase:Predicted transcriptional regulators:Transcriptional regulators:Membrane transporters of cations and cationic drugs:Lysophospholipase L1 and related esterases:Lipid A core - O-antigen ligase and related enzymes:Glycopeptide antibiotics resistance protein:Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain:Amino acid transport and metabolism:Coenzyme transport and metabolism:Transcription:Replication, recombination and repair:Cell wall/membrane/envelope biogenesis:Inorganic ion transport and metabolism:General function prediction only:Signal transduction mechanisms:birA_ligase:GGDEF:Defense mechanisms:Metabolism:Cellular processes and signaling:Information storage and processing:Poorly characterized:Signal transduction:Protein modification and repair:Protein fate:Other" 133 "2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase:Molybdopterin biosynthesis enzyme:ABC-type sugar transport system, permease component:Glycerol uptake facilitator and related permeases (Major Intrinsic Protein Family):Predicted dehydrogenases and related proteins:ABC-type antimicrobial peptide transport system, ATPase component:Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific:Beta-glucosidase-related glycosidases:Alpha-glucosidases, family 31 of glycosyl hydrolases:Transcriptional regulator/sugar kinase:Sugar phosphate permease:Beta-glucanase/Beta-glucan synthetase:Beta-glucosidase/6-phospho-beta-glucosidase/beta-galactosidase:Carbohydrate transport and metabolism:Coenzyme transport and metabolism:Lipid transport and metabolism:Transcription:General function prediction only:ispF:molyb_syn:EIIB_glc:MIP:SP:Defense mechanisms:PTS:Signal transduction:Other:Biosynthesis of cofactors, prosthetic groups, and carriers:Carbohydrates, organic alcohols, and acids:Unknown substrate:Transport and binding proteins:Information storage and processing:Cellular processes and signaling:Metabolism:Poorly characterized" 134 "Energy production and conversion:Integral membrane protein possibly involved in chromosome condensation:Predicted dehydrogenases and related proteins:Methyl-accepting chemotaxis protein:Type II secretory pathway, prepilin signal peptidase PulO and related peptidases:FOG: GGDEF domain:Aldehyde:ferredoxin oxidoreductase:Predicted membrane protein:Predicted ATPase:Signal transduction histidine kinase:Cell cycle control, cell division, chromosome partitioning:Cell motility:Posttranslational modification, protein turnover, chaperones:General function prediction only:Function unknown:Signal transduction mechanisms:sensory_box:GGDEF:crcB:TIGR04086_membr:Intracellular trafficking, secretion, and vesicular transport:Other:Metabolism:Cellular processes and signaling:Poorly characterized:Signal transduction:General:Unknown function:Small molecule interactions:Regulatory functions" 135 "Mn-dependent transcriptional regulator:Regulators of stationary/sporulation gene expression:Uncharacterized conserved protein:Spore coat protein:Transcription:Cell wall/membrane/envelope biogenesis:Function unknown:lp_hng_hel_AbrB:spore_yabG:spore_ytfJ:SASP_tlp:Sporulation and germination:Cellular processes:Information storage and processing:Regulatory functions:DNA interactions:Cellular processes and signaling:Poorly characterized" 136 "Energy production and conversion:2-polyprenylphenol hydroxylase and related flavodoxin oxidoreductases:Predicted sugar phosphate isomerase involved in capsule formation:Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes:Phosphotransferase system, mannose/fructose-specific component IIA:Phosphotransferase system, galactitol-specific IIB component:Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IIB:Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IIC:Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IID:Phosphotransferase system, galactitol-specific IIC component:Predicted oxidoreductase:Spore coat protein:Carbohydrate transport and metabolism:Coenzyme transport and metabolism:Cell wall/membrane/envelope biogenesis:General function prediction only:2A0309:GPR:sulfite_red_B:RuMP_HxlB:Central intermediary metabolism:Cellular processes:Metabolism:Cellular processes and signaling:Sporulation and germination:Poorly characterized:Amino acids, peptides and amines:Transport and binding proteins:Sulfur metabolism" 137 "UDP-N-acetylglucosamine 2-epimerase:Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis:Glycosyltransferase:Biotin synthase and related enzymes:Transcriptional regulator:Signal transduction histidine kinase:Asp-tRNAAsn/Glu-tRNAGln amidotransferase C subunit:Methyl-accepting chemotaxis protein:ABC-type spermidine/putrescine transport system, permease component I:Predicted membrane protein:Flagellar motor protein:Transcriptional regulators:Periplasmic molybdate-binding protein/domain:Ribosomal protein L11 methylase:Predicted signal transduction protein with a C-terminal ATPase domain:Predicted nucleotidyltransferase:Uncharacterized protein conserved in bacteria:ABC-type uncharacterized transport systems, ATPase components:Predicted kinase:Amino acid transport and metabolism:Coenzyme transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:Cell wall/membrane/envelope biogenesis:Cell motility:Inorganic ion transport and metabolism:General function prediction only:Function unknown:Signal transduction mechanisms:gatC:wecB:HDIG:prmA:yihY_not_rbn:excise:rSAM_HydE:General:Unknown function:Protein modification and repair:Protein fate:Ribosomal proteins: synthesis and modification:tRNA aminoacylation:Protein synthesis:Metabolism:Poorly characterized:Cellular processes and signaling:Information storage and processing:Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides:Cell envelope" 138 "Lyzozyme M1 (1,4-beta-N-acetylmuramidase):Site-specific recombinase XerD:Replication, recombination and repair:Cell wall/membrane/envelope biogenesis:Information storage and processing:Cellular processes and signaling" 139 "Predicted ATP-dependent protease:DNA replication protein:Regulators of stationary/sporulation gene expression:Uncharacterized conserved protein:Lyzozyme M1 (1,4-beta-N-acetylmuramidase):Ethanolamine ammonia-lyase, small subunit:Amino acid transport and metabolism:Transcription:Replication, recombination and repair:Cell wall/membrane/envelope biogenesis:Posttranslational modification, protein turnover, chaperones:Function unknown:lp_hng_hel_AbrB:Cellular processes and signaling:Information storage and processing:DNA interactions:Regulatory functions:Poorly characterized:Metabolism" 140 "Biotin-(acetyl-CoA carboxylase) ligase:Transcriptional regulator:Signal transduction histidine kinase:Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain:ABC-type multidrug transport system, ATPase component:ABC-type multidrug transport system, ATPase and permease components:A/G-specific DNA glycosylase:Transcriptional regulator:Transcriptional regulators:Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain:AraC-type DNA-binding domain-containing proteins:Arabinose efflux permease:Predicted membrane protein:Chloramphenicol O-acetyltransferase:Signal transduction histidine kinase:Uncharacterized conserved protein:Carbohydrate transport and metabolism:Coenzyme transport and metabolism:Transcription:Replication, recombination and repair:Function unknown:Signal transduction mechanisms:birA_ligase:thia_yuaJ:Defense mechanisms:Metabolism:Cellular processes and signaling:Information storage and processing:Poorly characterized:Transport and binding proteins:Protein modification and repair:Protein fate:Other" 141 "Isopropylmalate/homocitrate/citramalate synthases:Ribonucleotide reductase, beta subunit:Glycosyltransferase:Nucleoside-diphosphate-sugar epimerases:Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily):Superoxide dismutase:Predicted phosphatase/phosphohexomutase:Methyl-accepting chemotaxis protein:ABC-type multidrug transport system, ATPase component:ABC-type antimicrobial peptide transport system, ATPase component:Metal-dependent hydrolases of the beta-lactamase superfamily III:Predicted drug exporters of the RND superfamily:Uncharacterized protein conserved in bacteria:Amino acid transport and metabolism:Nucleotide transport and metabolism:Carbohydrate transport and metabolism:Cell wall/membrane/envelope biogenesis:Cell motility:Inorganic ion transport and metabolism:General function prediction only:Function unknown:Signal transduction mechanisms:HAD-SF-IA-v3:Defense mechanisms:Enzymes of unknown specificity:Unknown function:Poorly characterized:Metabolism:Cellular processes and signaling" 142 "Energy production and conversion:Transketolase:Predicted ATPase of the PP-loop superfamily implicated in cell cycle control:tRNA-dihydrouridine synthase:Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase:Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), B subunit:Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases:Glycosyltransferase:Multimeric flavodoxin WrbA:Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, alpha subunit:Protease subunit of ATP-dependent Clp proteases:UDP-N-acetylmuramoylalanine-D-glutamate ligase:Nitroreductase:DNA polymerase III, epsilon subunit and related 3'-5' exonucleases:ABC-type multidrug transport system, ATPase component:Predicted membrane GTPase involved in stress response:ABC-type transport system involved in multi-copper enzyme maturation, permease component:Transcriptional regulators of sugar metabolism:Predicted transcriptional regulators:Uncharacterized conserved protein:NADH:flavin oxidoreductases, Old Yellow Enzyme family:Galactose mutarotase and related enzymes:L-arabinose isomerase:Uncharacterized FAD-dependent dehydrogenases:Beta-xylosidase:Uncharacterized protein conserved in bacteria:Bacterial surface proteins containing Ig-like domains:Cell cycle control, cell division, chromosome partitioning:Amino acid transport and metabolism:Carbohydrate transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:Replication, recombination and repair:Cell wall/membrane/envelope biogenesis:Cell motility:Posttranslational modification, protein turnover, chaperones:General function prediction only:Function unknown:Signal transduction mechanisms:small_GTP:tktlase_bact:araD:murD:hisC:lysidine_TilS_N:spore_YlmC_YmxH:OAFO_sf:Intracellular trafficking, secretion, and vesicular transport:Defense mechanisms:Amino acid biosynthesis:General:Unknown function:Sporulation and germination:Cellular processes:tRNA and rRNA base modification:Protein synthesis:Sugars:Pentose phosphate pathway:Energy metabolism:Histidine family:Cell envelope:Biosynthesis and degradation of murein sacculus and peptidoglycan:Information storage and processing:Cellular processes and signaling:Metabolism:Poorly characterized" 143 "Guanosine polyphosphate pyrophosphohydrolases/synthetases:UDP-N-acetylglucosamine 2-epimerase:Glycosyltransferase:ATPases involved in chromosome partitioning:Zn-dependent hydrolases, including glyoxylases:Coproporphyrinogen III oxidase and related Fe-S oxidoreductases:Predicted glycosyltransferases:D-Tyr-tRNAtyr deacylase:Preprotein translocase subunit YajC:Membrane protein involved in the export of O-antigen and teichoic acid:Capsular polysaccharide biosynthesis protein:Cell cycle control, cell division, chromosome partitioning:Coenzyme transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:Cell wall/membrane/envelope biogenesis:General function prediction only:Signal transduction mechanisms:wecB:TIGR00256:spoT_relA:yajC:eps_fam:rSAM_HemZ:Intracellular trafficking, secretion, and vesicular transport:Metabolism:Cellular processes and signaling:Information storage and processing:Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides:Cell envelope:Heme, porphyrin, and cobalamin:Biosynthesis of cofactors, prosthetic groups, and carriers:Adaptations to atypical conditions:Cellular processes:Carbohydrates, organic alcohols, and acids:Transport and binding proteins:Protein and peptide secretion and trafficking:Protein fate:tRNA aminoacylation:Poorly characterized:Protein synthesis" 144 "Energy production and conversion:Nitrogen regulatory protein PII:Zn-dependent hydrolases, including glyoxylases:Na+-driven multidrug efflux pump:Cell division protein FtsI/penicillin-binding protein 2:ABC-type multidrug transport system, ATPase component:ABC-type antimicrobial peptide transport system, ATPase component:ABC-type sugar transport systems, permease components:ABC-type sugar transport system, periplasmic component:Nitrogenase molybdenum-iron protein, alpha and beta chains:Predicted dithiol-disulfide isomerase involved in polyketide biosynthesis:Cyanate permease:Predicted membrane protein:Bacterial surface proteins containing Ig-like domains:Amino acid transport and metabolism:Carbohydrate transport and metabolism:Cell wall/membrane/envelope biogenesis:Cell motility:Inorganic ion transport and metabolism:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:Function unknown:matE:nifK:exosort_Gpos:Defense mechanisms:Cellular processes and signaling:Other:Poorly characterized:Nitrogen fixation:Central intermediary metabolism:Transport and binding proteins:Metabolism" 145 "ABC-type sugar transport system, permease component:Glycosyltransferase:Nucleoside-diphosphate-sugar epimerases:Methyl-accepting chemotaxis protein:Polyphosphate kinase:ABC-type multidrug transport system, ATPase component:ABC-type antimicrobial peptide transport system, ATPase component:Predicted transcriptional regulators:Predicted membrane protein:Uncharacterized conserved protein:Uncharacterized protein conserved in bacteria:Carbohydrate transport and metabolism:Transcription:Cell wall/membrane/envelope biogenesis:Cell motility:Inorganic ion transport and metabolism:Function unknown:Signal transduction mechanisms:spore_ger_x_C:poly_P_kin:Defense mechanisms:Metabolism:Cellular processes and signaling:Information storage and processing:Poorly characterized:Cellular processes:Phosphorus compounds:Central intermediary metabolism:Sporulation and germination" 146 "Isoleucyl-tRNA synthetase:Adenylate kinase and related kinases:DNA polymerase III, alpha subunit:Predicted permease:dUTPase:Hydrolases of the alpha/beta superfamily:ABC-type metal ion transport system, ATPase component:Transcriptional regulators of sugar metabolism:Methionine synthase I, cobalamin-binding domain:DNA polymerase III, delta subunit:ABC-type metal ion transport system, permease component:Uncharacterized protein involved in tellurite resistance:Uncharacterized protein conserved in bacteria:Amino acid transport and metabolism:Nucleotide transport and metabolism:Carbohydrate transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:Replication, recombination and repair:Inorganic ion transport and metabolism:General function prediction only:Function unknown:ileS:dut:polc:holA:metH:Amino acid biosynthesis:tRNA aminoacylation:Protein synthesis:DNA replication, recombination, and repair:DNA metabolism:2'-Deoxyribonucleotide metabolism:Purines, pyrimidines, nucleosides, and nucleotides:Metabolism:Poorly characterized:Information storage and processing:Aspartate family" 147 "Energy production and conversion:Arginyl-tRNA synthetase:Cystathionine beta-lyases/cystathionine gamma-synthases:Flavodoxins:ABC-type amino acid transport system, permease component:ABC-type amino acid transport/signal transduction systems, periplasmic component/domain:ABC-type polar amino acid transport system, ATPase component:ABC-type multidrug transport system, ATPase component:Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific:Predicted transcriptional regulators:Transcriptional regulators:D-alanyl-D-alanine carboxypeptidase:Transcriptional regulator/sugar kinase:Predicted membrane protein:Predicted membrane protein:Signal transduction histidine kinase:Uncharacterized conserved protein:Amino acid transport and metabolism:Carbohydrate transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:Cell wall/membrane/envelope biogenesis:Function unknown:Signal transduction mechanisms:argS:ROK_glcA_fam:EIIB_glc:HEQRo_perm_3TM:Defense mechanisms:Information storage and processing:PTS:Signal transduction:General:Poorly characterized:Amino acids, peptides and amines:Transport and binding proteins:tRNA aminoacylation:Protein synthesis:Unknown function:Metabolism:Cellular processes and signaling" 148 "Acetyltransferase (isoleucine patch superfamily):Dihydrodipicolinate reductase:Selenocysteine lyase:Methyl-accepting chemotaxis protein:Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases):ADP-ribosylglycohydrolase:Predicted membrane protein/domain:Periplasmic molybdate-binding protein/domain:Nitrate/nitrite transporter:Endoglucanase:Predicted esterase of the alpha-beta hydrolase superfamily:NAD+--asparagine ADP-ribosyltransferase:Amino acid transport and metabolism:Carbohydrate transport and metabolism:Lipid transport and metabolism:Cell motility:Posttranslational modification, protein turnover, chaperones:Inorganic ion transport and metabolism:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:Function unknown:Signal transduction mechanisms:dapB:excise:Metabolism:Cellular processes and signaling:Aspartate family:Amino acid biosynthesis:General:Unknown function:Poorly characterized" 149 "Preprotein translocase subunit SecF:Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain:Transcription elongation factor:Predicted amidophosphoribosyltransferases:Phosphatidylserine synthase:Predicted transcriptional regulators:Transcriptional regulators:AraC-type DNA-binding domain-containing proteins:DnaJ-class molecular chaperone:Superfamily II DNA/RNA helicase required for DNA uptake (late competence protein):Signal transduction histidine kinase:Lipid transport and metabolism:Transcription:Replication, recombination and repair:Posttranslational modification, protein turnover, chaperones:General function prediction only:Signal transduction mechanisms:pssA:2A0604s01:greA:Intracellular trafficking, secretion, and vesicular transport:Cellular processes and signaling:Information storage and processing:Protein and peptide secretion and trafficking:Protein fate:Transcription factors:Transcription:Biosynthesis:Fatty acid and phospholipid metabolism:Metabolism:Poorly characterized" 150 "Energy production and conversion:Polyferredoxin:Glycosyltransferases involved in cell wall biogenesis:ATP-dependent Zn proteases:Transcriptional regulator:Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily):Glycine/D-amino acid oxidases (deaminating):Predicted xylanase/chitin deacetylase:ABC-type multidrug transport system, permease component:Lactate dehydrogenase and related dehydrogenases:Imidazolonepropionase and related amidohydrolases:Transcriptional regulator:D-mannonate dehydratase:Subtilisin-like serine proteases:Membrane-associated lipoprotein involved in thiamine biosynthesis:Predicted membrane protein:Predicted transcriptional regulators:FOG: GGDEF domain:Predicted membrane protein:Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IIB:Beta-xylosidase:Uncharacterized membrane protein:Predicted multitransmembrane protein:Amino acid transport and metabolism:Carbohydrate transport and metabolism:Coenzyme transport and metabolism:Transcription:Cell wall/membrane/envelope biogenesis:Posttranslational modification, protein turnover, chaperones:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:Function unknown:Signal transduction mechanisms:uxuA:FtsH_fam:pip_yhgE_Nterm:Defense mechanisms:Cellular processes and signaling:Information storage and processing:Degradation of proteins, peptides, and glycopeptides:Poorly characterized:Sugars:Energy metabolism:Protein fate:Metabolism" 151 "Aspartokinases:Cell division protein FtsI/penicillin-binding protein 2:UDP-N-acetylmuramyl tripeptide synthase:Methyl-accepting chemotaxis protein:Predicted nucleotidyltransferase:Predicted transcriptional regulators:Mn2+ and Fe2+ transporters of the NRAMP family:Predicted membrane-bound metal-dependent hydrolases:Endoglucanase:Tfp pilus assembly protein PilF:Predicted glutamine amidotransferase:Response regulator with putative antiterminator output domain:Predicted permease, DMT superfamily:Amino acid transport and metabolism:Carbohydrate transport and metabolism:Transcription:Cell wall/membrane/envelope biogenesis:Cell motility:Inorganic ion transport and metabolism:General function prediction only:Signal transduction mechanisms:asp_kinases:Intracellular trafficking, secretion, and vesicular transport:Information storage and processing:Aspartate family:Amino acid biosynthesis:Poorly characterized:Metabolism:Cellular processes and signaling" 152 "Uncharacterized conserved protein:Translation elongation factor P (EF-P)/translation initiation factor 5A (eIF-5A):Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain:Adenine/guanine phosphoribosyltransferases and related PRPP-binding proteins:Predicted transcriptional regulator, consists of a Zn-ribbon and ATP-cone domains:Transcriptional regulators:Predicted membrane protein:Predicted hydrolase (metallo-beta-lactamase superfamily):Growth inhibitor:Alpha-acetolactate decarboxylase:Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains:Nucleotide transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:Posttranslational modification, protein turnover, chaperones:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:Function unknown:Signal transduction mechanisms:efp:TIGR00244:TIGR01033:apt:acetolac_decarb:Fermentation:Energy metabolism:Protein synthesis:Metabolism:Poorly characterized:Information storage and processing:Translation factors:Cellular processes and signaling:DNA interactions:Regulatory functions:Salvage of nucleosides and nucleotides:Purines, pyrimidines, nucleosides, and nucleotides" 153 "Energy production and conversion:Ribosomal protein S10:Ribosomal protein L11:Ribosomal protein L10:Phosphate/sulphate permeases:Acetyltransferases:Spermidine/putrescine-binding periplasmic protein:Deoxycytidine deaminase:Predicted ATPase or kinase:NifU homolog involved in Fe-S cluster formation:ABC-type multidrug transport system, ATPase and permease components:ABC-type spermidine/putrescine transport system, permease component I:ABC-type spermidine/putrescine transport system, permease component II:Inactive homolog of metal-dependent proteases, putative molecular chaperone:Uncharacterized conserved protein:Phosphate transport regulator (distant homolog of PhoU):ABC-type spermidine/putrescine transport systems, ATPase components:Amino acid transport and metabolism:Nucleotide transport and metabolism:Translation, ribosomal structure and biogenesis:Posttranslational modification, protein turnover, chaperones:Inorganic ion transport and metabolism:General function prediction only:Function unknown:HI0065_YjeE:rpsJ_bact:potA:rimI:L11_bact:dCTP_deam:bact_YeaZ:Defense mechanisms:Amino acids, peptides and amines:Transport and binding proteins:Ribosomal proteins: synthesis and modification:Protein synthesis:2'-Deoxyribonucleotide metabolism:Purines, pyrimidines, nucleosides, and nucleotides:Unknown function:Enzymes of unknown specificity:Information storage and processing:Cellular processes and signaling:Metabolism:Poorly characterized" 154 "Excinuclease ATPase subunit:DNA repair exonuclease:NADPH-dependent glutamate synthase beta chain and related oxidoreductases:Topoisomerase IA:Helicase subunit of the DNA excision repair complex:ABC-type antimicrobial peptide transport system, permease component:Type I site-specific restriction-modification system, R (restriction) subunit and related helicases:Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain:Methyl-accepting chemotaxis protein:Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases):ABC-type antimicrobial peptide transport system, ATPase component:Uncharacterized protein conserved in bacteria:DNA-binding protein, stimulates sugar fermentation:Uncharacterized protein conserved in bacteria:Cytochrome P450:Predicted metal-dependent hydrolases related to alanyl-tRNA synthetase HxxxH domain:Predicted HD-superfamily hydrolase:Uncharacterized protein conserved in bacteria:Amino acid transport and metabolism:Lipid transport and metabolism:Transcription:Replication, recombination and repair:Cell motility:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:Function unknown:Signal transduction mechanisms:sfsA:HDIG:sbcd:uvra:uvrb:MG103:topB:TIGR02271:spore_ger_x_C:Defense mechanisms:DNA replication, recombination, and repair:DNA metabolism:Poorly characterized:Regulatory functions:Other:Metabolism:Cellular processes and signaling:Information storage and processing:Conserved:Hypothetical proteins:Sporulation and germination:Cellular processes" 155 "Glucan phosphorylase:Biotin carboxyl carrier protein:FOG: CheY-like receiver:Cell wall-associated hydrolases (invasion-associated proteins):Beta-galactosidase:Beta-lactamase class A:Putative peptidoglycan-binding domain-containing protein:Uncharacterized protein conserved in bacteria:Carbohydrate transport and metabolism:Lipid transport and metabolism:Cell wall/membrane/envelope biogenesis:Function unknown:Signal transduction mechanisms:P_ylase:Defense mechanisms:Energy metabolism:Poorly characterized:Metabolism:Cellular processes and signaling:Biosynthesis and degradation of polysaccharides" 156 "Phosphoheptose isomerase:Glycosyltransferase:Uncharacterized membrane protein, putative virulence factor:Methyl-accepting chemotaxis protein:Predicted membrane protein involved in D-alanine export:FOG: GGDEF domain:Uncharacterized conserved protein:Bacterial surface proteins containing Ig-like domains:Predicted integral membrane protein:Carbohydrate transport and metabolism:Cell wall/membrane/envelope biogenesis:Cell motility:General function prediction only:Function unknown:Signal transduction mechanisms:GGDEF:mviN:Metabolism:Cellular processes and signaling:Other:Signal transduction:General:Unknown function:Poorly characterized" 157 "Dimethyladenosine transferase (rRNA methylation):Glutamate 5-kinase:ATPase components of ABC transporters with duplicated ATPase domains:Predicted hydrolases of the HAD superfamily:Signal transduction histidine kinase:Multimeric flavodoxin WrbA:ABC-type transport system involved in multi-copper enzyme maturation, permease component:Transcriptional regulator:DNA replication protein:Uncharacterized conserved protein:Homocysteine/selenocysteine methylase (S-methylmethionine-dependent):Uncharacterized protein conserved in bacteria:Aminoglycoside N3'-acetyltransferase:Acyl-ACP thioesterase:Amino acid transport and metabolism:Lipid transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:Replication, recombination and repair:General function prediction only:Function unknown:Signal transduction mechanisms:Cof-subfamily:TIGR00299:ksgA:proB:Defense mechanisms:Information storage and processing:Glutamate family:Amino acid biosynthesis:Enzymes of unknown specificity:Unknown function:Conserved:Hypothetical proteins:tRNA and rRNA base modification:Protein synthesis:Cellular processes and signaling:Metabolism:Poorly characterized" 158 "Predicted phosphatases:Transcriptional regulator:ABC-type multidrug transport system, ATPase component:ABC-type antimicrobial peptide transport system, ATPase component:A/G-specific DNA glycosylase:Uncharacterized protein conserved in bacteria:Transcriptional regulators:Uncharacterized membrane protein, possible Na+ channel or pump:AraC-type DNA-binding domain-containing proteins:Arabinose efflux permease:ATP-dependent transcriptional regulator:Predicted membrane protein:Carbohydrate transport and metabolism:Transcription:Replication, recombination and repair:General function prediction only:Function unknown:HAD-SF-IA-v1:thia_yuaJ:Defense mechanisms:Metabolism:Cellular processes and signaling:Information storage and processing:Poorly characterized:Unknown function:Other:Transport and binding proteins:Enzymes of unknown specificity" 159 "tRNA and rRNA cytosine-C5-methylases:5-formyltetrahydrofolate cyclo-ligase:Methionyl-tRNA formyltransferase:N-formylmethionyl-tRNA deformylase:Mismatch repair ATPase (MutS family):Predicted Zn-dependent proteases and their inactivated homologs:DNA mismatch repair enzyme (predicted ATPase):tRNA delta(2)-isopentenylpyrophosphate transferase:Uncharacterized conserved protein:Aspartate/tyrosine/aromatic aminotransferase:Glycosyltransferase:DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32):2-methylthioadenine synthetase:ATP-dependent exoDNAse (exonuclease V) beta subunit (contains helicase and exonuclease domains):Sugar phosphate isomerases/epimerases:Deoxyxylulose-5-phosphate synthase:Aspartyl aminopeptidase:Uncharacterized protein conserved in bacteria:Serine kinase of the HPr protein, regulates carbohydrate metabolism:Exonuclease VII small subunit:Predicted Zn-dependent protease:ATP-dependent nuclease, subunit B:Uncharacterized protein conserved in bacteria:Amino acid transport and metabolism:Carbohydrate transport and metabolism:Coenzyme transport and metabolism:Lipid transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:Replication, recombination and repair:Cell wall/membrane/envelope biogenesis:General function prediction only:Function unknown:Signal transduction mechanisms:pept_deformyl:TIGR00089:miaA:dxs:fmt:YbgI_SA1388:rsmB:mutl:mutS1:RpoD_Cterm:MTHFS_bact:addB_Gpos:addA_Gpos:exosort_Gpos:Protein synthesis:Information storage and processing:Cellular processes and signaling:Metabolism:Poorly characterized:Biosynthesis of cofactors, prosthetic groups, and carriers:General:Unknown function:Protein modification and repair:Protein fate:tRNA and rRNA base modification:tRNA aminoacylation:Thiamine:Transcription factors:Transcription:DNA replication, recombination, and repair:DNA metabolism:One-carbon metabolism:Central intermediary metabolism" 160 "Phosphate/sulphate permeases:Predicted S-adenosylmethionine-dependent methyltransferase involved in bacterial cell division:Uncharacterized conserved protein:FOG: CBS domain:Metal-dependent proteases with possible chaperone activity:Deoxycytidine deaminase:N-acetylmuramoyl-L-alanine amidase:ABC-type multidrug transport system, ATPase and permease components:Inactive homolog of metal-dependent proteases, putative molecular chaperone:Phosphate transport regulator (distant homolog of PhoU):Predicted transcriptional regulators:Uracil-DNA glycosylase:Predicted RNA-binding protein:Pyrimidine operon attenuation protein/uracil phosphoribosyltransferase:Xanthine/uracil permeases:Peptide chain release factor RF-3:Nucleotide transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:Replication, recombination and repair:Cell wall/membrane/envelope biogenesis:Posttranslational modification, protein turnover, chaperones:Inorganic ion transport and metabolism:General function prediction only:Function unknown:gidB:parB_part:small_GTP:gcp_kae1:ncs2:dCTP_deam:spore_cwlD:bact_YeaZ:Defense mechanisms:Protein fate:tRNA and rRNA base modification:Protein synthesis:2'-Deoxyribonucleotide metabolism:Purines, pyrimidines, nucleosides, and nucleotides:Transport and binding proteins:Metabolism:Cellular processes and signaling:Information storage and processing:General:Unknown function:Sporulation and germination:Cellular processes:Nucleosides, purines and pyrimidines:Poorly characterized:Degradation of proteins, peptides, and glycopeptides" 161 "Energy production and conversion:Site-specific DNA methylase:Na+-driven multidrug efflux pump:ABC-type sugar transport systems, permease components:ABC-type sugar transport system, periplasmic component:Nitrogenase molybdenum-iron protein, alpha and beta chains:Zinc metalloprotease (elastase):Type IV secretory pathway, VirB4 components:Uncharacterized protein conserved in bacteria:Amino acid transport and metabolism:Carbohydrate transport and metabolism:Replication, recombination and repair:Function unknown:dcm:matE:nifE:Intracellular trafficking, secretion, and vesicular transport:Defense mechanisms:Cellular processes and signaling:Information storage and processing:Other:Transport and binding proteins:DNA replication, recombination, and repair:DNA metabolism:Nitrogen fixation:Central intermediary metabolism:Metabolism:Poorly characterized" 162 "Nucleoside diphosphate kinase:Predicted membrane protein:FOG: Ankyrin repeat:Transcriptional regulator/sugar kinase:SOS-response transcriptional repressors (RecA-mediated autopeptidases):Putative stress-responsive transcriptional regulator:FOG: GGDEF domain:Methylase involved in ubiquinone/menaquinone biosynthesis:Uncharacterized conserved protein, contains double-stranded beta-helix domain:Predicted acetyltransferase:Nucleotide transport and metabolism:Carbohydrate transport and metabolism:Coenzyme transport and metabolism:Transcription:General function prediction only:Function unknown:Signal transduction mechanisms:TIGR00023:GGDEF:lexA:Biosynthesis:Fatty acid and phospholipid metabolism:Information storage and processing:Metabolism:Cellular processes and signaling:Poorly characterized:Other:Signal transduction:DNA interactions:Regulatory functions" 163 "Uncharacterized conserved protein:Thiamine biosynthesis protein ThiC:Organic radical activating enzymes:Uncharacterized protein conserved in bacteria:Sugar diacid utilization regulator:ABC-type oligopeptide transport system, periplasmic component:Amino acid transport and metabolism:Coenzyme transport and metabolism:Transcription:Posttranslational modification, protein turnover, chaperones:Function unknown:Signal transduction mechanisms:thiC:NrdG:exosort_Gpos:Information storage and processing:Poorly characterized:Thiamine:Biosynthesis of cofactors, prosthetic groups, and carriers:Protein modification and repair:Protein fate:Cellular processes and signaling:Metabolism" 164 "Energy production and conversion:ABC-type sugar transport system, permease component:Membrane-fusion protein:ABC-type sugar transport systems, permease components:DNA-directed RNA polymerase specialized sigma subunit:Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor):ABC-type sugar transport system, periplasmic component:Glycosyl transferases, related to UDP-glucuronosyltransferase:NADH:flavin oxidoreductases, Old Yellow Enzyme family:Anti-sigma regulatory factor (Ser/Thr protein kinase):Carbohydrate transport and metabolism:Transcription:Cell wall/membrane/envelope biogenesis:Signal transduction mechanisms:ant_ant_sig:MGT:spIIAB:spore_sigF:Sporulation and germination:Toxin production and resistance:Cellular processes:Protein interactions:Regulatory functions:Cellular processes and signaling:Metabolism:Information storage and processing" 165 "Energy production and conversion:Arginase/agmatinase/formimionoglutamate hydrolase, arginase family:Adenine/guanine phosphoribosyltransferases and related PRPP-binding proteins:ATP-dependent exoDNAse (exonuclease V), alpha subunit - helicase superfamily I member:Glycerophosphoryl diester phosphodiesterase:Small-conductance mechanosensitive channel:Nitroreductase:Methyl-accepting chemotaxis protein:Transcriptional regulator:Acetyltransferases, including N-acetylases of ribosomal proteins:2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase:Anaerobic C4-dicarboxylate transporter:Arabinose efflux permease:Predicted glycosyl hydrolase:Flp pilus assembly protein TadD, contains TPR repeats:Amino acid transport and metabolism:Nucleotide transport and metabolism:Carbohydrate transport and metabolism:Coenzyme transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:Replication, recombination and repair:Cell wall/membrane/envelope biogenesis:Cell motility:General function prediction only:Signal transduction mechanisms:Dcu:rocF_arginase:XPRTase:SAM_7_link_chp:Intracellular trafficking, secretion, and vesicular transport:Carbohydrates, organic alcohols, and acids:Transport and binding proteins:Poorly characterized:Purines, pyrimidines, nucleosides, and nucleotides:Salvage of nucleosides and nucleotides:Metabolism:Cellular processes and signaling:Information storage and processing" 166 "Energy production and conversion:Excinuclease ATPase subunit:Molybdenum cofactor biosynthesis enzyme:(acyl-carrier-protein) S-malonyltransferase:ABC-type Fe3+-siderophore transport system, permease component:Transcription elongation factor:Predicted endonuclease distantly related to archaeal Holliday junction resolvase:Predicted thioesterase:Fe-S oxidoreductase:3-hydroxyacyl-CoA dehydrogenase:Predicted thioesterase involved in non-ribosomal peptide biosynthesis:Indolepyruvate ferredoxin oxidoreductase, alpha and beta subunits:ABC-type transport system, involved in lipoprotein release, permease component:Uncharacterized protein containing a NRPS condensation (elongation) domain:Coenzyme transport and metabolism:Lipid transport and metabolism:Transcription:Replication, recombination and repair:Cell wall/membrane/envelope biogenesis:Inorganic ion transport and metabolism:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:TIGR00252:moaC:greA:IOR_alpha:Information storage and processing:Molybdopterin:Biosynthesis of cofactors, prosthetic groups, and carriers:Conserved:Hypothetical proteins:Transcription factors:Transcription:Metabolism:Poorly characterized:Cellular processes and signaling" 167 "Energy production and conversion:Predicted phosphoesterase:Cystathionine beta-lyases/cystathionine gamma-synthases:Nitroreductase:FOG: CheY-like receiver:Septum formation inhibitor:Hydrolases of the alpha/beta superfamily:Gamma-aminobutyrate permease and related permeases:Transcriptional regulator:Beta-galactosidase, beta subunit:Uncharacterized protein conserved in bacteria:Uncharacterized conserved protein:Cell cycle control, cell division, chromosome partitioning:Amino acid transport and metabolism:Carbohydrate transport and metabolism:Transcription:General function prediction only:Function unknown:Signal transduction mechanisms:TIGR00022:yfcE:minC:Information storage and processing:General:Enzymes of unknown specificity:Unknown function:Cell division:Cellular processes:Metabolism:Poorly characterized:Cellular processes and signaling" 168 "Energy production and conversion:Glycosyltransferase:Predicted Zn-dependent peptidases:Arylsulfatase regulator (Fe-S oxidoreductase):6-pyruvoyl-tetrahydropterin synthase:Predicted hydrolase (HAD superfamily):Fe-S oxidoreductase:ABC-type multidrug transport system, ATPase and permease components:Glycosyltransferases, probably involved in cell wall biogenesis:Predicted glycosyltransferases:FOG: GGDEF domain:Membrane protein involved in the export of O-antigen and teichoic acid:Coenzyme transport and metabolism:Cell wall/membrane/envelope biogenesis:General function prediction only:Signal transduction mechanisms:glyc2_xrt_Gpos1:6_pyr_pter_rel:Defense mechanisms:Poorly characterized:Metabolism:Cellular processes and signaling" 169 "Energy production and conversion:Isopropylmalate/homocitrate/citramalate synthases:Glycosyltransferases involved in cell wall biogenesis:Zn-dependent hydrolases, including glyoxylases:Nitroreductase:ABC-type multidrug transport system, permease component:Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases):ABC-type multidrug transport system, ATPase component:Glycosyltransferases, probably involved in cell wall biogenesis:Uncharacterized conserved protein:D-mannonate dehydratase:ABC-type Na+ efflux pump, permease component:FOG: GGDEF domain:Membrane protein involved in the export of O-antigen and teichoic acid:Predicted membrane protein:Nitrogenase molybdenum-iron protein, alpha and beta chains:Uncharacterized protein conserved in bacteria:Arabinose efflux permease:Predicted beta-xylosidase:Amino acid transport and metabolism:Carbohydrate transport and metabolism:Lipid transport and metabolism:Cell wall/membrane/envelope biogenesis:Inorganic ion transport and metabolism:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:Function unknown:Signal transduction mechanisms:uxuA:2A0105:nifK:spore_V_B:exosort_Gpos:glyc2_xrt_Gpos1:Defense mechanisms:Carbohydrates, organic alcohols, and acids:Transport and binding proteins:Sugars:Poorly characterized:Nitrogen fixation:Central intermediary metabolism:Energy metabolism:Metabolism:Cellular processes and signaling:Sporulation and germination:Cellular processes" 170 "Mannitol-1-phosphate/altronate dehydrogenases:UDP-glucose 4-epimerase:Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific:Transcriptional regulators of sugar metabolism:Alpha-galactosidases/6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases:DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog:Galactose mutarotase and related enzymes:Na+/melibiose symporter and related transporters:Altronate dehydratase:Endoglucanase:Arabinose efflux permease:Phosphotransferase system, galactitol-specific IIB component:Beta-xylosidase:Transcriptional antiterminator:Phosphotransferase system, galactitol-specific IIC component:Arabinogalactan endo-1,4-beta-galactosidase:Predicted beta-xylosidase:Predicted unsaturated glucuronyl hydrolase involved in regulation of bacterial surface properties, and related proteins:Mannitol/fructose-specific phosphotransferase system, IIA domain:Carbohydrate transport and metabolism:Transcription:Cell wall/membrane/envelope biogenesis:General function prediction only:gph:EIIB_glc:SP:galE:rpoN_sigma:PTS:Signal transduction:Carbohydrates, organic alcohols, and acids:Transport and binding proteins:Transcription factors:Transcription:Sugars:Energy metabolism:Metabolism:Poorly characterized:Cellular processes and signaling:Information storage and processing" 171 "Aspartyl/asparaginyl-tRNA synthetases:Isopropylmalate/homocitrate/citramalate synthases:Site-specific DNA methylase:Cation/multidrug efflux pump:Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases):ABC-type antimicrobial peptide transport system, ATPase component:Isopentenyldiphosphate isomerase:HD-GYP domain:Phage anti-repressor protein:Mu-like prophage protein Com:Amino acid transport and metabolism:Lipid transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:Replication, recombination and repair:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:Signal transduction mechanisms:aspS_arch:dam:spore_ger_x_C:Defense mechanisms:Cellular processes and signaling:Information storage and processing:Sporulation and germination:Cellular processes:tRNA aminoacylation:Protein synthesis:DNA replication, recombination, and repair:DNA metabolism:Metabolism:Poorly characterized" 172 "Energy production and conversion:Adenylosuccinate synthase:4-aminobutyrate aminotransferase and related aminotransferases:Mismatch repair ATPase (MutS family):Deoxyribose-phosphate aldolase:Predicted Zn-dependent proteases and their inactivated homologs:Membrane protease subunits, stomatin/prohibitin homologs:Phosphopantothenoylcysteine synthetase/decarboxylase:Predicted GTPase:ATPases with chaperone activity, ATP-binding subunit:ABC-type amino acid transport system, permease component:Primosomal protein N' (replication factor Y) - superfamily II helicase:dTDP-glucose pyrophosphorylase:Hemolysins and related proteins containing CBS domains:Uncharacterized conserved protein:Predicted RNA-binding protein containing KH domain, possibly ribosomal protein:Membrane protein implicated in regulation of membrane protease activity:DNA-directed RNA polymerase, subunit K/omega:Phage shock protein A (IM30), suppresses sigma54-dependent transcription:Uncharacterized oxidoreductases, Fe-dependent alcohol dehydrogenase family:Beta-glucosidase/6-phospho-beta-glucosidase/beta-galactosidase:Predicted secreted protein:Amino acid transport and metabolism:Nucleotide transport and metabolism:Carbohydrate transport and metabolism:Coenzyme transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:Replication, recombination and repair:Cell wall/membrane/envelope biogenesis:Posttranslational modification, protein turnover, chaperones:General function prediction only:Function unknown:Signal transduction mechanisms:deoC:purA:small_GTP:coaBC_dfp:priA:rpoZ:TIGR00726:mutS1:rmlA:HEQRo_perm_3TM:Intracellular trafficking, secretion, and vesicular transport:Purine ribonucleotide biosynthesis:Purines, pyrimidines, nucleosides, and nucleotides:Other:Energy metabolism:Transport and binding proteins:Metabolism:Cellular processes and signaling:Information storage and processing:Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides:Cell envelope:Pantothenate and coenzyme A:Biosynthesis of cofactors, prosthetic groups, and carriers:General:Unknown function:Amino acids, peptides and amines:Poorly characterized:DNA-dependent RNA polymerase:Transcription:DNA replication, recombination, and repair:DNA metabolism" 173 "Superfamily I DNA and RNA helicases:DNA primase (bacterial type):dUTPase:Uncharacterized protein conserved in bacteria:Nucleotide transport and metabolism:Replication, recombination and repair:Function unknown:dut:Information storage and processing:2'-Deoxyribonucleotide metabolism:Purines, pyrimidines, nucleosides, and nucleotides:Metabolism:Poorly characterized" 174 "UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N-acetylglucosamine-1-phosphate transferase:Kef-type K+ transport systems, membrane components:FOG: CBS domain:Transcriptional regulator:Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain:Alanine racemase:DNA-directed RNA polymerase specialized sigma subunit:Glycosyltransferases, probably involved in cell wall biogenesis:4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family:Galactose mutarotase and related enzymes:Predicted flavoproteins:ABC-type spermidine/putrescine transport systems, ATPase components:ABC-type uncharacterized transport system, permease component:Iron only hydrogenase large subunit, C-terminal domain:Amino acid transport and metabolism:Carbohydrate transport and metabolism:Transcription:Cell wall/membrane/envelope biogenesis:Inorganic ion transport and metabolism:General function prediction only:Signal transduction mechanisms:TIGR00275:alr:potA:spore_sigG:Information storage and processing:Biosynthesis and degradation of murein sacculus and peptidoglycan:Cell envelope:Enzymes of unknown specificity:Unknown function:Sporulation and germination:Cellular processes:Amino acids, peptides and amines:Transport and binding proteins:Metabolism:Poorly characterized:Cellular processes and signaling" 175 "Sugar kinases, ribokinase family:Single-stranded DNA-binding protein:Predicted membrane protein:Predicted pyrophosphatase:Uncharacterized protein conserved in bacteria:Glycopeptide antibiotics resistance protein:Carbohydrate transport and metabolism:Replication, recombination and repair:General function prediction only:Function unknown:ssb:efflux_EmrB:Defense mechanisms:Poorly characterized:Information storage and processing:Other:Transport and binding proteins:DNA replication, recombination, and repair:DNA metabolism:Cellular processes and signaling:Metabolism" 176 "Acetyltransferase (isoleucine patch superfamily):Aspartate-semialdehyde dehydrogenase:Dihydrodipicolinate synthase/N-acetylneuraminate lyase:Transcriptional regulator:Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily):ABC-type multidrug transport system, ATPase and permease components:Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily:Transcriptional regulators:Predicted membrane protein:Predicted membrane protein:Uncharacterized vancomycin resistance protein:Uncharacterized protein conserved in bacteria:Amino acid transport and metabolism:Transcription:Cell wall/membrane/envelope biogenesis:General function prediction only:Function unknown:dapA:asd_EA:spore_YtaF:Defense mechanisms:Cellular processes and signaling:Information storage and processing:Aspartate family:Poorly characterized:Sporulation and germination:Cellular processes:Amino acid biosynthesis:Metabolism" 177 "Energy production and conversion:Ribosomal protein S4 and related proteins:Ribose 5-phosphate isomerase RpiB:Predicted xylanase/chitin deacetylase:Predicted hydrolase (HAD superfamily):Predicted ATP-dependent protease:GDP-D-mannose dehydratase:ABC-type proline/glycine betaine transport systems, ATPase components:6Fe-6S prismane cluster-containing protein:ABC-type proline/glycine betaine transport systems, permease component:Acyl carrier protein phosphodiesterase:Periplasmic glycine betaine/choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein):Uncharacterized protein conserved in bacteria:Amino acid transport and metabolism:Carbohydrate transport and metabolism:Lipid transport and metabolism:Translation, ribosomal structure and biogenesis:Cell wall/membrane/envelope biogenesis:Posttranslational modification, protein turnover, chaperones:General function prediction only:Function unknown:rpsD_bact:gmd:HAD-SF-IA-v3:CO_DH_cata:spore_pdaA:spore_lonB:Cellular processes:Ribosomal proteins: synthesis and modification:Protein synthesis:Enzymes of unknown specificity:Metabolism:Cellular processes and signaling:Information storage and processing:Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides:Cell envelope:Poorly characterized:Unknown function:Sporulation and germination" 178 "Energy production and conversion:Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase:Transcriptional regulator:Single-stranded DNA-binding protein:Transcriptional regulators:Acetyltransferases, including N-acetylases of ribosomal proteins:NADH:flavin oxidoreductases, Old Yellow Enzyme family:Polyketide synthase modules and related proteins:Putative peptidoglycan-binding domain-containing protein:Lantibiotic modifying enzyme:Membrane protein putatively involved in post-translational modification of the autoinducing quorum-sensing peptide:Predicted integral membrane protein:Amino acid transport and metabolism:Coenzyme transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:Replication, recombination and repair:Cell wall/membrane/envelope biogenesis:Posttranslational modification, protein turnover, chaperones:Secondary metabolites biosynthesis, transport and catabolism:Function unknown:Signal transduction mechanisms:6_pyr_pter_rel:Defense mechanisms:Poorly characterized:Metabolism:Cellular processes and signaling:Information storage and processing" 179 "Undecaprenyl pyrophosphate synthase:Conserved domain frequently associated with peptide methionine sulfoxide reductase:Putative translation initiation inhibitor, yjgF family:Preprotein translocase subunit SecD:ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component:Zn-dependent protease with chaperone function:Transcriptional regulator:Predicted phosphatase/phosphohexomutase:Arylsulfatase regulator (Fe-S oxidoreductase):Predicted xylanase/chitin deacetylase:Septum formation inhibitor:16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases:Transcriptional regulator:Predicted transcriptional regulators:Phosphotransferase system IIA components:Cell cycle control, cell division, chromosome partitioning:Amino acid transport and metabolism:Carbohydrate transport and metabolism:Lipid transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:Posttranslational modification, protein turnover, chaperones:Inorganic ion transport and metabolism:General function prediction only:TIGR00093:TIGR00357:PTBA:2A0604s01:minC:HAD-SF-IA-v3:oligo_HPY:spore_II_R:spore_YpeB:rSAM_six_Cys:Intracellular trafficking, secretion, and vesicular transport:Information storage and processing:PTS:Signal transduction:Enzymes of unknown specificity:Unknown function:Sporulation and germination:Adaptations to atypical conditions:Cell division:Cellular processes:Amino acids, peptides and amines:Transport and binding proteins:Protein and peptide secretion and trafficking:Protein fate:tRNA and rRNA base modification:Protein synthesis:Cellular processes and signaling:Metabolism:Poorly characterized" 180 "Protease subunit of ATP-dependent Clp proteases:Phage terminase, small subunit:Lyzozyme M1 (1,4-beta-N-acetylmuramidase):Phage-related protein:Phage-related tail protein:Bacteriophage head-tail adaptor:Replication, recombination and repair:Cell wall/membrane/envelope biogenesis:Posttranslational modification, protein turnover, chaperones:General function prediction only:Function unknown:portal_HK97:sm_term_P27:put_DNA_pack:gp16_SPP1:maj_tail_phi13:put_anti_recept:phge_HK97_gp10:tape_meas_TP901:Intracellular trafficking, secretion, and vesicular transport:Poorly characterized:Mobile and extrachromosomal element functions:Prophage functions:Information storage and processing:Cellular processes and signaling" 181 "ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components:DNA replication protein:Regulators of stationary/sporulation gene expression:Lyzozyme M1 (1,4-beta-N-acetylmuramidase):Transcription:Replication, recombination and repair:Cell wall/membrane/envelope biogenesis:Inorganic ion transport and metabolism:lp_hng_hel_AbrB:DNA interactions:Metabolism:Regulatory functions:Cellular processes and signaling:Information storage and processing" 182 "Energy production and conversion:Purine nucleoside phosphorylase:Predicted Co/Zn/Cd cation transporters:Prephenate dehydratase:Integral membrane protein possibly involved in chromosome condensation:Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain:ATP-dependent Lon protease, bacterial type:Zn-dependent hydrolases, including glyoxylases:ABC-type transport system involved in Fe-S cluster assembly, permease component:Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain:Acetyl-CoA carboxylase beta subunit:Periplasmic protease:Enzyme involved in the deoxyxylulose pathway of isoprenoid biosynthesis:6Fe-6S prismane cluster-containing protein:Predicted transcriptional regulators:Phosphosulfolactate phosphohydrolase and related enzymes:Peroxiredoxin:Uncharacterized FAD-dependent dehydrogenases:Predicted signaling protein consisting of a modified GGDEF domain and a DHH domain:Predicted membrane protein:Cell cycle control, cell division, chromosome partitioning:Amino acid transport and metabolism:Nucleotide transport and metabolism:Coenzyme transport and metabolism:Lipid transport and metabolism:Transcription:Cell wall/membrane/envelope biogenesis:Posttranslational modification, protein turnover, chaperones:Inorganic ion transport and metabolism:General function prediction only:Function unknown:Signal transduction mechanisms:prc:crcB:accD:ispG_gcpE:lon:CDF:PNPH-PUNA-XAPA:CO_DH_cata:sufB:Cations and iron carrying compounds:Transport and binding proteins:Protein modification and repair:Degradation of proteins, peptides, and glycopeptides:Protein fate:Biosynthesis:Fatty acid and phospholipid metabolism:Information storage and processing:Poorly characterized:Cellular processes and signaling:Metabolism:Other:Biosynthesis of cofactors, prosthetic groups, and carriers:General:Unknown function" 183 "Energy production and conversion:Malic enzyme:3-oxoacyl-(acyl-carrier-protein) synthase:4-hydroxybenzoate polyprenyltransferase and related prenyltransferases:Phosphatidylserine decarboxylase:ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components:Membrane-associated lipoprotein involved in thiamine biosynthesis:FOG: FHA domain:FOG: GGDEF domain:Sugar phosphate permease:Carbohydrate transport and metabolism:Coenzyme transport and metabolism:Lipid transport and metabolism:Inorganic ion transport and metabolism:Secondary metabolites biosynthesis, transport and catabolism:Signal transduction mechanisms:GGDEF:2A0309:YD_repeat_2x:fabF:Other:Cellular processes and signaling:Metabolism:Signal transduction:Amino acids, peptides and amines:Transport and binding proteins:Biosynthesis:Fatty acid and phospholipid metabolism" 184 "Energy production and conversion:Aspartate oxidase:Quinolinate synthase:ADP-glucose pyrophosphorylase:Superfamily I DNA and RNA helicases and helicase subunits:Rubrerythrin:Type II secretory pathway, pseudopilin PulG:Uncharacterized protein conserved in bacteria:Beta-mannanase:Carbohydrate transport and metabolism:Coenzyme transport and metabolism:Replication, recombination and repair:Cell motility:Function unknown:nadA:glgC:IV_pilin_GFxxxE:Intracellular trafficking, secretion, and vesicular transport:Biosynthesis of cofactors, prosthetic groups, and carriers:Protein and peptide secretion and trafficking:Protein fate:Biosynthesis and degradation of polysaccharides:Energy metabolism:Pyridine nucleotides:Metabolism:Cellular processes and signaling:Information storage and processing:Poorly characterized" 185 "Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain:Predicted hydrolase (HAD superfamily):Imidazolonepropionase and related amidohydrolases:Predicted metal-dependent membrane protease:Arsenate reductase and related proteins, glutaredoxin family:Acetyltransferases, including N-acetylases of ribosomal proteins:Uncharacterized protein conserved in bacteria:Predicted membrane-bound metal-dependent hydrolases:Transcriptional regulators:Methylase involved in ubiquinone/menaquinone biosynthesis:Response regulator of the LytR/AlgR family:Uncharacterized conserved protein:Uncharacterized protein conserved in bacteria:Uncharacterized protein conserved in bacteria:Signal transduction histidine kinase:Coenzyme transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:Inorganic ion transport and metabolism:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:Function unknown:Signal transduction mechanisms:2A0309:HAD-SF-IA-v3:Metabolism:Cellular processes and signaling:Information storage and processing:Enzymes of unknown specificity:Unknown function:Amino acids, peptides and amines:Transport and binding proteins:Poorly characterized" 186 "Lyzozyme M1 (1,4-beta-N-acetylmuramidase):Phage-related protein:Phage-related protein:Phage-related protein:Bacterial surface proteins containing Ig-like domains:Cell wall/membrane/envelope biogenesis:Cell motility:Function unknown:phi3626_gp14_N:put_anti_recept:Mobile and extrachromosomal element functions:Cellular processes and signaling:Poorly characterized:Prophage functions" 187 "3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase and related enzymes:Replicative DNA helicase:DNA polymerase III, alpha subunit:Single-stranded DNA-specific exonuclease:Predicted Fe-S-cluster redox enzyme:Oxygen-sensitive ribonucleoside-triphosphate reductase:Uncharacterized protein conserved in bacteria:Amino acid transport and metabolism:Nucleotide transport and metabolism:Coenzyme transport and metabolism:Replication, recombination and repair:General function prediction only:Function unknown:polc:recJ:NrdD:Information storage and processing:DNA replication, recombination, and repair:DNA metabolism:2'-Deoxyribonucleotide metabolism:Purines, pyrimidines, nucleosides, and nucleotides:Poorly characterized:Metabolism" 188 "Energy production and conversion:Predicted Fe-S oxidoreductases:Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, alpha subunit:Nitroreductase:Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases):Threonine dehydrogenase and related Zn-dependent dehydrogenases:Ferredoxin:6Fe-6S prismane cluster-containing protein:Pyruvate-formate lyase-activating enzyme:Predicted glycosyltransferases:Cellobiose phosphorylase:Mn-containing catalase:Uncharacterized conserved protein:Spore coat protein:Amino acid transport and metabolism:Carbohydrate transport and metabolism:Lipid transport and metabolism:Cell wall/membrane/envelope biogenesis:Posttranslational modification, protein turnover, chaperones:Inorganic ion transport and metabolism:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:Function unknown:CO_DH_cata:pyruv_ox_red:TIGR02328:spore_IV_A:rSAM_NirJ1:Hypothetical proteins:Sporulation and germination:Cellular processes:Metabolism:Poorly characterized:Cellular processes and signaling:Conserved" 189 "Energy production and conversion:2-polyprenylphenol hydroxylase and related flavodoxin oxidoreductases:NADH:flavin oxidoreductases, Old Yellow Enzyme family:Uncharacterized protein conserved in bacteria:Coenzyme transport and metabolism:Function unknown:sulfite_red_B:WXG100_ESAT6:Sulfur metabolism:Poorly characterized:Central intermediary metabolism:Metabolism" 190 "ATP-dependent Zn proteases:Predicted choline kinase involved in LPS biosynthesis:Superoxide dismutase:Predicted phosphatase/phosphohexomutase:Predicted membrane metal-binding protein:UDP-N-acetyl-D-mannosaminuronate dehydrogenase:Predicted xylanase/chitin deacetylase:ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component:Subtilisin-like serine proteases:Metal-dependent amidase/aminoacylase/carboxypeptidase:Transposase and inactivated derivatives:Site-specific recombinases, DNA invertase Pin homologs:Predicted membrane protein:Sporulation protein and related proteins:Uncharacterized protein conserved in bacteria:Cell cycle control, cell division, chromosome partitioning:Carbohydrate transport and metabolism:Replication, recombination and repair:Cell wall/membrane/envelope biogenesis:Posttranslational modification, protein turnover, chaperones:Inorganic ion transport and metabolism:General function prediction only:Function unknown:FtsH_fam:HAD-SF-IA-v3:SpoIID_LytB:spore_CotS:NDP-sugDHase:General:Enzymes of unknown specificity:Unknown function:Sporulation and germination:Cellular processes:Degradation of proteins, peptides, and glycopeptides:Protein fate:Metabolism:Poorly characterized:Cellular processes and signaling:Information storage and processing" 191 "Glutamate-1-semialdehyde aminotransferase:Uroporphyrinogen-III methylase:Delta-aminolevulinic acid dehydratase:Porphobilinogen deaminase:6-phosphofructokinase:Cysteinyl-tRNA synthetase:Predicted methyltransferases:Glutamyl-tRNA reductase:Fructose-2,6-bisphosphatase:Prolyl-tRNA synthetase:Pyruvate kinase:6-pyruvoyl-tetrahydropterin synthase:Glycosyltransferases, probably involved in cell wall biogenesis:Uncharacterized proteins, homologs of microcin C7 resistance protein MccF:Siroheme synthase (precorrin-2 oxidase/ferrochelatase domain):Predicted transcriptional regulators:Mn2+ and Fe2+ transporters of the NRAMP family:FOG: GGDEF domain:Beta-mannanase:Predicted membrane protein:Carbohydrate transport and metabolism:Coenzyme transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:Cell wall/membrane/envelope biogenesis:Inorganic ion transport and metabolism:General function prediction only:Function unknown:Signal transduction mechanisms:TIGR00096:hemC:GGDEF:proS_fam_II:cysS:hemL:hemA:pyruv_kin:cobA_cysG_Cterm:PFKA_ATP:exosort_Gpos:glyc2_xrt_Gpos1:6_pyr_pter_rel:Defense mechanisms:Protein synthesis:Metabolism:Cellular processes and signaling:Information storage and processing:Other:Signal transduction:Heme, porphyrin, and cobalamin:Biosynthesis of cofactors, prosthetic groups, and carriers:Enzymes of unknown specificity:Unknown function:tRNA aminoacylation:Poorly characterized:Glycolysis/gluconeogenesis:Energy metabolism" 192 "Chemotaxis protein histidine kinase and related kinases:Chemotaxis signal transduction protein:Flagellar hook-associated protein:Uncharacterized flagellar protein FlaG:Flagellin and related hook-associated proteins:Flagellar capping protein:Methylase of chemotaxis methyl-accepting proteins:Flagellin-specific chaperone FliS:Carbon storage regulator (could also regulate swarming and quorum sensing):Uncharacterized protein conserved in bacteria:Chemotaxis protein CheC, inhibitor of MCP methylation:Flagellar motor switch protein:Chemotaxis protein; stimulates methylation of MCP proteins:Chemotaxis response regulator containing a CheY-like receiver domain and a methylesterase domain:Negative regulator of flagellin synthesis (anti-sigma28 factor):Uncharacterized protein conserved in bacteria:Flagellar basal body rod protein:Transcription:Cell motility:Posttranslational modification, protein turnover, chaperones:Function unknown:Signal transduction mechanisms:csrA:fliS:fliM_switch:flgK_ends:flg_new:flagell_flgL:FlgEFG_subfam:FlgM_jcvi:Intracellular trafficking, secretion, and vesicular transport:Regulatory functions:RNA interactions:Cellular processes:Chemotaxis and motility:Information storage and processing:Cellular processes and signaling:Poorly characterized" 193 "Glutamine phosphoribosylpyrophosphate amidotransferase:Phosphoribosylcarboxyaminoimidazole (NCAIR) mutase:Phosphoglycerate dehydrogenase and related dehydrogenases:AICAR transformylase/IMP cyclohydrolase PurH (only IMP cyclohydrolase domain in Aful):Phosphoribosylaminoimidazole (AIR) synthetase:Phosphoribosylaminoimidazolesuccinocarboxamide (SAICAR) synthase:Seryl-tRNA synthetase:Folate-dependent phosphoribosylglycinamide formyltransferase PurN:GTP cyclohydrolase I:Organic radical activating enzymes:Predicted PP-loop superfamily ATPase:6-pyruvoyl-tetrahydropterin synthase:Benzoyl-CoA reductase/2-hydroxyglutaryl-CoA dehydratase subunit, BcrC/BadD/HgdB:Uncharacterized conserved protein:Amino acid transport and metabolism:Nucleotide transport and metabolism:Coenzyme transport and metabolism:Translation, ribosomal structure and biogenesis:Posttranslational modification, protein turnover, chaperones:General function prediction only:Function unknown:folE:purC:purH:TIGR00364:serS:PurN:purM:purF:purE:queuosine_QueD:rSAM_QueE_Clost:Biosynthesis of cofactors, prosthetic groups, and carriers:General:Unknown function:tRNA and rRNA base modification:Poorly characterized:Protein synthesis:Purine ribonucleotide biosynthesis:Purines, pyrimidines, nucleosides, and nucleotides:tRNA aminoacylation:Metabolism:Cellular processes and signaling:Information storage and processing:Folic acid" 194 "Fatty acid/phospholipid biosynthesis enzyme:Glycosyltransferase:RNase P protein component:Phosphopantetheine adenylyltransferase:Signal peptidase I:Preprotein translocase subunit YidC:Uncharacterized conserved protein:Disulfide bond chaperones of the HSP33 family:Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily:ABC-type polysaccharide/polyol phosphate export systems, permease component:Sugar transferases involved in lipopolysaccharide synthesis:Carbohydrate transport and metabolism:Coenzyme transport and metabolism:Lipid transport and metabolism:Translation, ribosomal structure and biogenesis:Cell wall/membrane/envelope biogenesis:Posttranslational modification, protein turnover, chaperones:Function unknown:cyt_tran_rel:plsX:rnpA:TIGR00278:sigpep_I_bact:EPS_sugtrans:yidC_oxa1_cterm:Intracellular trafficking, secretion, and vesicular transport:Protein fate:RNA processing:Transcription:Biosynthesis:Fatty acid and phospholipid metabolism:Poorly characterized:Information storage and processing:Metabolism:Conserved:Hypothetical proteins:Protein and peptide secretion and trafficking:Cellular processes and signaling" 195 "Lyzozyme M1 (1,4-beta-N-acetylmuramidase):Site-specific recombinase XerD:Replication, recombination and repair:Cell wall/membrane/envelope biogenesis:Information storage and processing:Cellular processes and signaling" 196 "Isopropylmalate/homocitrate/citramalate synthases:Methionyl-tRNA synthetase:Leucyl-tRNA synthetase:Permeases of the drug/metabolite transporter (DMT) superfamily:ABC-type amino acid transport system, permease component:ABC-type amino acid transport/signal transduction systems, periplasmic component/domain:Serine acetyltransferase:Thiamine biosynthesis enzyme ThiH and related uncharacterized enzymes:Branched-chain amino acid permeases:ABC-type polar amino acid transport system, ATPase component:Phosphopantetheinyl transferase:O-acetylhomoserine sulfhydrylase:Predicted transcriptional regulator:Uncharacterized protein conserved in bacteria:Predicted multitransmembrane protein:Amino acid transport and metabolism:Carbohydrate transport and metabolism:Coenzyme transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:General function prediction only:Function unknown:Signal transduction mechanisms:leuS_bact:metG:pantethn_trn:livcs:leuA_yeast:cysE:OAH_OAS_sulfhy:HEQRo_perm_3TM:rSAM_HydG:Transport and binding proteins:Metabolism:Poorly characterized:Information storage and processing:Serine family:Pyruvate family:Amino acid biosynthesis:Amino acids, peptides and amines:Cellular processes and signaling:Protein modification and repair:Protein fate:tRNA aminoacylation:Protein synthesis" 197 "ATP phosphoribosyltransferase:Phosphoribosylformimino-5-aminoimidazole carboxamide ribonucleotide (ProFAR) isomerase:Imidazoleglycerol-phosphate synthase:Glutamine amidotransferase:Imidazoleglycerol-phosphate dehydratase:Phosphoribosyl-AMP cyclohydrolase:Histidinol dehydrogenase:Membrane-associated phospholipid phosphatase:Uncharacterized conserved protein:ATP phosphoribosyltransferase involved in histidine biosynthesis:Amino acid transport and metabolism:Lipid transport and metabolism:Function unknown:TIGR00007:hisD:hisG:hisZ_biosyn_reg:hisF:IMP_synth_hisH:beta_rpt_yvtn:Poorly characterized:Histidine family:Amino acid biosynthesis:Metabolism" 198 "Thiamine biosynthesis ATP pyrophosphatase:Glycosyltransferase:RNase P protein component:Preprotein translocase subunit YidC:Uncharacterized conserved protein:Lysine efflux permease:Predicted RNA-binding protein homologous to eukaryotic snRNP:Putative effector of murein hydrolase:Putative effector of murein hydrolase LrgA:ABC-type polysaccharide/polyol phosphate export systems, permease component:Predicted RNA-binding protein:Sugar transferases involved in lipopolysaccharide synthesis:Bacterial surface proteins containing Ig-like domains:Carbohydrate transport and metabolism:Coenzyme transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:Cell wall/membrane/envelope biogenesis:Cell motility:General function prediction only:Function unknown:rnpA:TIGR00278:TIGR00342:EPS_sugtrans:yidC_oxa1_cterm:Intracellular trafficking, secretion, and vesicular transport:Protein synthesis:RNA processing:Transcription:Hypothetical proteins:Metabolism:Cellular processes and signaling:Information storage and processing:Conserved:Poorly characterized:Protein and peptide secretion and trafficking:Protein fate:tRNA and rRNA base modification" 199 "Dethiobiotin synthetase:Adenosylmethionine-8-amino-7-oxononanoate aminotransferase:Biotin synthase and related enzymes:DNA-directed RNA polymerase specialized sigma subunit:Uncharacterized conserved protein:Predicted transcriptional regulators:Cu/Zn superoxide dismutase:Uncharacterized conserved protein:Coenzyme transport and metabolism:Transcription:Inorganic ion transport and metabolism:General function prediction only:Function unknown:bioD:bioB:bioA:spore_sigmaE:spore_II_GA:Biotin:Poorly characterized:Information storage and processing:Metabolism:Biosynthesis of cofactors, prosthetic groups, and carriers:Sporulation and germination:Cellular processes" 200 "Energy production and conversion:Thymidine phosphorylase:Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain:Deoxyribose-phosphate aldolase:ATPases with chaperone activity, ATP-binding subunit:Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, beta subunit:DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog:Transcriptional regulators:Uncharacterized oxidoreductases, Fe-dependent alcohol dehydrogenase family:FOG: GGDEF domain:Methylase involved in ubiquinone/menaquinone biosynthesis:Membrane protein involved in the export of O-antigen and teichoic acid:Alpha-tubulin suppressor and related RCC1 domain-containing proteins:Cell cycle control, cell division, chromosome partitioning:Nucleotide transport and metabolism:Coenzyme transport and metabolism:Transcription:Posttranslational modification, protein turnover, chaperones:General function prediction only:Signal transduction mechanisms:deoC:PorB_KorB:Y_phosphoryl:sigma70-ECF:Cytoskeleton:Information storage and processing:Other:Poorly characterized:Other:Energy metabolism:Purines, pyrimidines, nucleosides, and nucleotides:Metabolism:Cellular processes and signaling" 201 "Predicted EndoIII-related endonuclease:Ribosomal protein S15P/S13E:Predicted S-adenosylmethionine-dependent methyltransferase involved in cell envelope biogenesis:Predicted enzyme with a TIM-barrel fold:ABC-type transport system involved in Fe-S cluster assembly, ATPase component:Amino acid transporters:Signal peptidase I:Prolipoprotein diacylglyceryltransferase:ABC-type transport system involved in Fe-S cluster assembly, permease component:Actin-like ATPase involved in cell division:Glycosyltransferases, probably involved in cell wall biogenesis:Uncharacterized protein conserved in bacteria:Transcriptional regulator of heat shock gene:Ribosome-associated protein Y (PSrp-1):D-alanyl-D-alanine carboxypeptidase:Uncharacterized protein conserved in bacteria:Formyltetrahydrofolate synthetase:Uncharacterized protein conserved in bacteria:Predicted glutamine amidotransferase:Cell cycle control, cell division, chromosome partitioning:Amino acid transport and metabolism:Nucleotide transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:Replication, recombination and repair:Cell wall/membrane/envelope biogenesis:Posttranslational modification, protein turnover, chaperones:General function prediction only:Function unknown:TIGR00006:TIGR00044:TIGR00046:hrcA:lgt:yfiA:S15_bact:rpmH_bact:nth:ftsA:sufC:sufD:sigpep_I_bact:Intracellular trafficking, secretion, and vesicular transport:Cell envelope:Other:Biosynthesis of cofactors, prosthetic groups, and carriers:Enzymes of unknown specificity:Unknown function:Cell division:Cellular processes:Protein modification and repair:Poorly characterized:Protein fate:Translation factors:tRNA and rRNA base modification:Ribosomal proteins: synthesis and modification:Protein synthesis:DNA replication, recombination, and repair:DNA metabolism:DNA interactions:Regulatory functions:Protein and peptide secretion and trafficking:Metabolism:Cellular processes and signaling:Information storage and processing:Biosynthesis and degradation of murein sacculus and peptidoglycan" 202 "Energy production and conversion:Diaminopimelate decarboxylase:Phosphoenolpyruvate synthase/pyruvate phosphate dikinase:Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain:ABC-type multidrug transport system, permease component:ABC-type multidrug transport system, ATPase component:Phosphatidylserine synthase:N-acetylglutamate synthase and related acetyltransferases:ADP-ribosylglycohydrolase:ABC-type Na+ efflux pump, permease component:FOG: GGDEF domain:Zinc metalloprotease (elastase):Transcriptional regulator, effector-binding domain/component:Bacterial surface proteins containing Ig-like domains:Amino acid transport and metabolism:Carbohydrate transport and metabolism:Lipid transport and metabolism:Transcription:Cell motility:Posttranslational modification, protein turnover, chaperones:Inorganic ion transport and metabolism:Signal transduction mechanisms:GGDEF:lysA:Defense mechanisms:Cellular processes and signaling:Information storage and processing:Other:Metabolism:Aspartate family:Amino acid biosynthesis:Signal transduction" 203 "Energy production and conversion:Glycosidases:Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, alpha subunit:Transcriptional regulators:Uncharacterized conserved protein:ABC-type Na+ efflux pump, permease component:Putative homoserine kinase type II (protein kinase fold):Mn-containing catalase:Cell wall hydrolyses involved in spore germination:Spore coat protein:Carbohydrate transport and metabolism:Transcription:Cell wall/membrane/envelope biogenesis:Inorganic ion transport and metabolism:General function prediction only:Function unknown:pyruv_ox_red:TIGR02328:spore_CotS:Cellular processes and signaling:Metabolism:Poorly characterized:Information storage and processing:Conserved:Hypothetical proteins:Sporulation and germination:Cellular processes" 204 "Co-chaperonin GroES (HSP10):Chaperonin GroEL (HSP60 family):NTP pyrophosphohydrolases including oxidative damage repair enzymes:Predicted dehydrogenase:Fructose-1-phosphate kinase and related fructose-6-phosphate kinase (PfkB):Phosphotransferase system, fructose-specific IIC component:Transcriptional regulators of sugar metabolism:ABC-type sugar transport system, periplasmic component:Phosphotransferase system mannitol/fructose-specific IIA domain (Ntr-type):Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain:Methylase involved in ubiquinone/menaquinone biosynthesis:Glucoamylase and related glycosyl hydrolases:Uncharacterized protein with conserved CXXC pairs:Signal transduction histidine kinase:Carbohydrate transport and metabolism:Coenzyme transport and metabolism:Transcription:Replication, recombination and repair:Posttranslational modification, protein turnover, chaperones:General function prediction only:Function unknown:Signal transduction mechanisms:FRU:fruA:GroEL:1-PFK:Information storage and processing:PTS:Signal transduction:Protein folding and stabilization:Protein fate:Metabolism:Poorly characterized:Cellular processes and signaling" 205 "Exopolyphosphatase:Signal transduction histidine kinase:5'-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases:DNA repair photolyase:Uncharacterized conserved protein:Flp pilus assembly protein TadC:DNA gyrase inhibitor:Transposase and inactivated derivatives:Beta-mannanase:Flp pilus assembly protein, ATPase CpaF:Nucleotide transport and metabolism:Carbohydrate transport and metabolism:Replication, recombination and repair:Cell motility:Inorganic ion transport and metabolism:Function unknown:Signal transduction mechanisms:TIGR00299:exo_poly_only:Intracellular trafficking, secretion, and vesicular transport:Metabolism:Cellular processes and signaling:Information storage and processing:Poorly characterized:Hypothetical proteins:Phosphorus compounds:Central intermediary metabolism:Conserved" 206 "Predicted Co/Zn/Cd cation transporters:Na+-driven multidrug efflux pump:Permeases of the drug/metabolite transporter (DMT) superfamily:Predicted xylanase/chitin deacetylase:Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain:Acetyl-CoA carboxylase alpha subunit:Aspartate ammonia-lyase:Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases):Hydrolases of the alpha/beta superfamily:Transcriptional regulators:Transcriptional regulators:Transcriptional regulators:Septum formation inhibitor-activating ATPase:Alpha-acetolactate decarboxylase:Predicted acetyltransferase:Uncharacterized protein conserved in bacteria:Pectin methylesterase:Predicted integral membrane protein:Cell cycle control, cell division, chromosome partitioning:Amino acid transport and metabolism:Carbohydrate transport and metabolism:Lipid transport and metabolism:Transcription:Inorganic ion transport and metabolism:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:Function unknown:Signal transduction mechanisms:accA:matE:acetolac_decarb:CDF:minD_bact:Defense mechanisms:Cell division:Cellular processes:Other:Cations and iron carrying compounds:Poorly characterized:Biosynthesis:Fatty acid and phospholipid metabolism:Fermentation:Energy metabolism:Transport and binding proteins:Metabolism:Cellular processes and signaling:Information storage and processing" 207 "Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain:Nuclease subunit of the excinuclease complex:Predicted permeases:Exonuclease III:Amino acid transporters:Methyl-accepting chemotaxis protein:ABC-type multidrug transport system, permease component:ABC-type multidrug transport system, ATPase component:Co/Zn/Cd efflux system component:Hemolysins and related proteins containing CBS domains:Uncharacterized conserved protein:Predicted membrane protein:D-alanyl-D-alanine carboxypeptidase:Mn2+ and Fe2+ transporters of the NRAMP family:Na+/melibiose symporter and related transporters:Predicted periplasmic or secreted lipoprotein:Sortase (surface protein transpeptidase):Amino acid transport and metabolism:Carbohydrate transport and metabolism:Replication, recombination and repair:Cell wall/membrane/envelope biogenesis:Cell motility:Posttranslational modification, protein turnover, chaperones:Inorganic ion transport and metabolism:General function prediction only:Function unknown:Signal transduction mechanisms:exoDNase_III:yihY_not_rbn:sortase_fam:CDF:Defense mechanisms:Information storage and processing:General:Unknown function:Cations and iron carrying compounds:Poorly characterized:Protein and peptide secretion and trafficking:Protein fate:DNA replication, recombination, and repair:DNA metabolism:Transport and binding proteins:Metabolism:Cellular processes and signaling" 208 "Predicted Co/Zn/Cd cation transporters:ATPases involved in chromosome partitioning:Cell division protein FtsI/penicillin-binding protein 2:Methyl-accepting chemotaxis protein:Thiamine biosynthesis enzyme ThiH and related uncharacterized enzymes:ABC-type multidrug transport system, ATPase and permease components:Predicted transcriptional regulators:Sulfur transfer protein involved in thiamine biosynthesis:Predicted membrane protein:Uncharacterized protein conserved in bacteria:Uncharacterized protein containing a NRPS condensation (elongation) domain:Cell cycle control, cell division, chromosome partitioning:Coenzyme transport and metabolism:Transcription:Cell wall/membrane/envelope biogenesis:Cell motility:Inorganic ion transport and metabolism:General function prediction only:Function unknown:Signal transduction mechanisms:CDF:thiS:thiH:thiF_fam2:spore_YyaC:sulfite_red_A:WXG100_ESAT6:Defense mechanisms:Biosynthesis of cofactors, prosthetic groups, and carriers:Cellular processes:Cations and iron carrying compounds:Transport and binding proteins:Sulfur metabolism:Central intermediary metabolism:Sporulation and germination:Poorly characterized:Metabolism:Cellular processes and signaling:Information storage and processing:Thiamine" 209 "Energy production and conversion:Molybdopterin biosynthesis enzyme:3-oxoacyl-[acyl-carrier-protein] synthase III:Thioredoxin reductase:NTP pyrophosphohydrolases including oxidative damage repair enzymes:Selenocysteine lyase:Molybdopterin biosynthesis enzymes:Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily):ABC-type transport system involved in Fe-S cluster assembly, permease component:NifU homolog involved in Fe-S cluster formation:Methyl-accepting chemotaxis protein:Enoyl-CoA hydratase/carnithine racemase:Transcriptional regulators:Glycosyl transferases, related to UDP-glucuronosyltransferase:Carbon starvation protein, predicted membrane protein:Predicted glutamine amidotransferases:Aldehyde:ferredoxin oxidoreductase:Leucine-rich repeat (LRR) protein:Uncharacterized protein containing a NRPS condensation (elongation) domain:Amino acid transport and metabolism:Carbohydrate transport and metabolism:Coenzyme transport and metabolism:Lipid transport and metabolism:Transcription:Replication, recombination and repair:Cell motility:Posttranslational modification, protein turnover, chaperones:General function prediction only:Function unknown:Signal transduction mechanisms:molyb_syn:TRX_reduct:MGT:sufS:sufD:SUF_scaf_2:prismane_assoc:Toxin production and resistance:Cellular processes:Electron transport:Energy metabolism:Metabolism:Poorly characterized:Cellular processes and signaling:Information storage and processing:Other:Biosynthesis of cofactors, prosthetic groups, and carriers" 210 "(acyl-carrier-protein) S-malonyltransferase:Glycosyltransferases involved in cell wall biogenesis:Collagenase and related proteases:Methyl-accepting chemotaxis protein:ABC-type multidrug transport system, ATPase component:Uncharacterized protein conserved in bacteria:Acetyltransferases, including N-acetylases of ribosomal proteins:Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain:Uncharacterized protein conserved in bacteria:Uncharacterized protein conserved in bacteria:Lipid transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:Cell wall/membrane/envelope biogenesis:Cell motility:Posttranslational modification, protein turnover, chaperones:Function unknown:Signal transduction mechanisms:fabD:Defense mechanisms:Information storage and processing:Biosynthesis:Fatty acid and phospholipid metabolism:Poorly characterized:Metabolism:Cellular processes and signaling" 211 "Geranylgeranyl pyrophosphate synthase:Ribosomal protein S1:Phosphatidylglycerophosphate synthase:tRNA nucleotidyltransferase/poly(A) polymerase:N6-adenine-specific methylase:Transcription termination factor:dTDP-4-dehydrorhamnose reductase:16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases:Glycosyltransferases, probably involved in cell wall biogenesis:Predicted glycosyltransferases:Metal-dependent hydrolases of the beta-lactamase superfamily I:Uncharacterized conserved protein:Predicted transcriptional regulator containing the HTH domain:Transcriptional regulators:dTDP-4-dehydrorhamnose 3,5-epimerase and related enzymes:Teichoic acid biosynthesis proteins:Lipid A core - O-antigen ligase and related enzymes:ACT domain-containing protein:Coenzyme transport and metabolism:Lipid transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:Replication, recombination and repair:Cell wall/membrane/envelope biogenesis:General function prediction only:Function unknown:Signal transduction mechanisms:TIGR00093:TIGR00095:ispH_lytB:TIGR00281:pgsA:wecG_tagA_cpsF:rmlD:rmlC:nusB:spore_yabP:spore_yabQ:Information storage and processing:Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides:Cell envelope:Other:Biosynthesis of cofactors, prosthetic groups, and carriers:Sporulation and germination:Cellular processes:Poorly characterized:Protein synthesis:Transcription factors:Transcription:Chromosome-associated proteins:DNA metabolism:Biosynthesis:Fatty acid and phospholipid metabolism:tRNA and rRNA base modification:Metabolism:Cellular processes and signaling" 212 "Short-chain dehydrogenases of various substrate specificities:Glycosyltransferase:Nucleoside-diphosphate-sugar epimerases:Phosphoenolpyruvate synthase/pyruvate phosphate dikinase:CDP-diglyceride synthetase:Multimeric flavodoxin WrbA:cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases:Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain:Methyl-accepting chemotaxis protein:Uncharacterized conserved protein:HD-GYP domain:Hemerythrin:Uncharacterized protein conserved in bacteria:Carbohydrate transport and metabolism:Lipid transport and metabolism:Transcription:Cell wall/membrane/envelope biogenesis:Cell motility:Inorganic ion transport and metabolism:General function prediction only:Function unknown:Signal transduction mechanisms:HDIG:hemeryth_dom:Information storage and processing:Metabolism:Poorly characterized:Cellular processes and signaling" 213 "Pseudouridine synthase:Transcription elongation factor:FAD synthase:Protein chain release factor A:Aspartokinases:Translation initiation factor 2 (IF-2; GTPase):Exopolyphosphatase-related proteins:Uncharacterized protein conserved in bacteria:Predicted Fe-S-cluster redox enzyme:Ribosome-binding factor A:Predicted GTPases:Chromosome segregation ATPases:Ribosomal protein HS6-type (S12/L30/L7a):Uncharacterized conserved protein:Predicted nucleic-acid-binding protein implicated in transcription termination:Superfamily I DNA and RNA helicases:Cell cycle control, cell division, chromosome partitioning:Amino acid transport and metabolism:Coenzyme transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:General function prediction only:Function unknown:prfA:TIGR00048:rbfA:ribF:TIGR00157:small_GTP:TruB:asp_kinases:NusA:SMC_prok_B:spore_YlmC_YmxH:Riboflavin, FMN, and FAD:Biosynthesis of cofactors, prosthetic groups, and carriers:Aspartate family:Amino acid biosynthesis:General:Unknown function:Sporulation and germination:Cellular processes:Poorly characterized:tRNA and rRNA base modification:Protein synthesis:RNA processing:Transcription factors:Transcription:Chromosome-associated proteins:DNA metabolism:Translation factors:Metabolism:Cellular processes and signaling:Information storage and processing" 214 "Energy production and conversion:Chloride channel protein EriC:Malate/lactate dehydrogenases:Phosphoribosylformylglycinamidine (FGAM) synthase, synthetase domain:Glutathione peroxidase:Ribosomal protein S4 and related proteins:Predicted Fe-S oxidoreductases:Predicted transcriptional regulators:Flavodoxins:Ferredoxin:Pyruvate-formate lyase-activating enzyme:Transcriptional regulators:Pyruvate-formate lyase:Fe2+ transport system protein A:Permeases:Uncharacterized protein conserved in bacteria:Nucleotide transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:Posttranslational modification, protein turnover, chaperones:Inorganic ion transport and metabolism:General function prediction only:Function unknown:rpsD_bact:pyr_form_ly_1:flav_short:L-LDH-NAD:FGAM-synthase:PFLA:Protein synthesis:Poorly characterized:Purines, pyrimidines, nucleosides, and nucleotides:Glycolysis/gluconeogenesis:Fermentation:Electron transport:Energy metabolism:Purine ribonucleotide biosynthesis:Metabolism:Cellular processes and signaling:Information storage and processing:Protein modification and repair:Protein fate:Ribosomal proteins: synthesis and modification" 215 "Mismatch repair ATPase (MutS family):6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase:Glycyl-tRNA synthetase (class II):Phosphoribosylpyrophosphate synthetase:Amino acid transporters:Prolipoprotein diacylglyceryltransferase:UDP-N-acetylglucosamine enolpyruvyl transferase:Cell division protein FtsI/penicillin-binding protein 2:UDP-N-acetylmuramate dehydrogenase:N-acetylmuramoyl-L-alanine amidase:Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog):Glycosyltransferases, probably involved in cell wall biogenesis:Uncharacterized conserved protein:Predicted transcriptional regulator containing the HTH domain:Mn2+ and Fe2+ transporters of the NRAMP family:Predicted membrane-bound metal-dependent hydrolases:Pleiotropic transcriptional repressor:ACT domain-containing protein:Amino acid transport and metabolism:Nucleotide transport and metabolism:Carbohydrate transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:Replication, recombination and repair:Cell wall/membrane/envelope biogenesis:Inorganic ion transport and metabolism:General function prediction only:Function unknown:murB:TIGR00281:glyS_dimeric:nagB:lgt:murA:ribP_PPkin:codY_Gpos:spore_cwlD:Metabolism:Cellular processes and signaling:Information storage and processing:Biosynthesis and degradation of murein sacculus and peptidoglycan:Cell envelope:Sporulation and germination:Cellular processes:Protein modification and repair:Protein fate:Poorly characterized:Protein synthesis:Chromosome-associated proteins:DNA metabolism:DNA interactions:Regulatory functions:Purine ribonucleotide biosynthesis:Purines, pyrimidines, nucleosides, and nucleotides:Amino sugars:Central intermediary metabolism:tRNA aminoacylation" 216 "Energy production and conversion:Predicted hydrolases of the HAD superfamily:Transcriptional regulator:Signal transduction histidine kinase:Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases):Sortase and related acyltransferases:Transcriptional regulator:Cellulase M and related proteins:Predicted phosphohydrolases:Predicted transcriptional regulators:Ketopantoate reductase:NADH:flavin oxidoreductases, Old Yellow Enzyme family:HD-GYP domain:Lysophospholipase L1 and related esterases:Beta-xylosidase:Predicted nucleotidyltransferase:Glycopeptide antibiotics resistance protein:Amino acid transport and metabolism:Carbohydrate transport and metabolism:Coenzyme transport and metabolism:Lipid transport and metabolism:Transcription:Cell wall/membrane/envelope biogenesis:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:Signal transduction mechanisms:Cof-subfamily:HDIG:Defense mechanisms:Metabolism:Cellular processes and signaling:Poorly characterized:Enzymes of unknown specificity:Unknown function:Information storage and processing" 217 "Cysteinyl-tRNA synthetase:Predicted methyltransferases:Prolyl-tRNA synthetase:ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component:Nucleoside-diphosphate-sugar epimerases:Predicted hydrolases of the HAD superfamily:ABC-type dipeptide/oligopeptide/nickel transport systems, permease components:Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain:Methyl-accepting chemotaxis protein:ABC-type dipeptide/oligopeptide/nickel transport systems, permease components:Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1:DNA repair photolyase:FOG: GGDEF domain:Tfp pilus assembly protein, pilus retraction ATPase PilT:Tfp pilus assembly protein PilF:Predicted O-methyltransferase:Amino acid transport and metabolism:Carbohydrate transport and metabolism:Coenzyme transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:Replication, recombination and repair:Cell wall/membrane/envelope biogenesis:Cell motility:Inorganic ion transport and metabolism:General function prediction only:Signal transduction mechanisms:TIGR00096:Cof-subfamily:GGDEF:proS_fam_II:cysS:pilT_fam:oligo_HPY:photo_TT_lyase:Intracellular trafficking, secretion, and vesicular transport:Protein synthesis:Unknown function:Metabolism:Cellular processes and signaling:Information storage and processing:Other:Signal transduction:Enzymes of unknown specificity:Poorly characterized:Sporulation and germination:Chemotaxis and motility:Cellular processes:Amino acids, peptides and amines:Transport and binding proteins:tRNA aminoacylation" 218 "Energy production and conversion:Malate/lactate dehydrogenases:Carbonic anhydrase:Fructose-2,6-bisphosphatase:Na+-driven multidrug efflux pump:Phosphoserine phosphatase:CDP-diglyceride synthetase:Phosphatidylserine decarboxylase:Nitroreductase:Pyruvate-formate lyase-activating enzyme:D-alanyl-D-alanine carboxypeptidase:Predicted transcriptional regulators:Predicted RNA-binding protein (contains KH domain):Transcriptional regulators:Pyruvate-formate lyase:Beta-galactosidase, beta subunit:Uncharacterized protein conserved in bacteria:Predicted membrane protein:Amino acid transport and metabolism:Carbohydrate transport and metabolism:Lipid transport and metabolism:Transcription:Cell wall/membrane/envelope biogenesis:Posttranslational modification, protein turnover, chaperones:Inorganic ion transport and metabolism:General function prediction only:Function unknown:TIGR00022:PS_decarb:matE:pyr_form_ly_1:HAD-SF-IB:L-LDH-NAD:PFLA:Defense mechanisms:Unknown function:Other:Transport and binding proteins:Protein modification and repair:Protein fate:Biosynthesis:Fatty acid and phospholipid metabolism:Glycolysis/gluconeogenesis:Fermentation:Energy metabolism:Enzymes of unknown specificity:General:Information storage and processing:Cellular processes and signaling:Metabolism:Poorly characterized" 219 "Galactokinase:Signal transduction histidine kinase:Methyl-accepting chemotaxis protein:ABC-type sugar transport systems, permease components:FOG: LysM repeat:Alpha-glucosidases, family 31 of glycosyl hydrolases:ABC-type sugar transport system, periplasmic component:Glucuronate isomerase:Na+/melibiose symporter and related transporters:3-carboxymuconate cyclase:Beta-glucosidase/6-phospho-beta-glucosidase/beta-galactosidase:Pectate lyase:Uncharacterized protein with a bacterial SH3 domain homologue:FOG: Glucan-binding domain (YG repeat):Carbohydrate transport and metabolism:Cell wall/membrane/envelope biogenesis:Cell motility:General function prediction only:Function unknown:Signal transduction mechanisms:gal_kin:gph:Metabolism:Cellular processes and signaling:Carbohydrates, organic alcohols, and acids:Transport and binding proteins:Sugars:Energy metabolism:Poorly characterized" 220 "Energy production and conversion:Aspartyl/asparaginyl-tRNA synthetases:Isopropylmalate/homocitrate/citramalate synthases:Predicted epimerase, PhzC/PhzF homolog:Thiol-disulfide isomerase and thioredoxins:ABC-type multidrug transport system, permease component:Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases):ABC-type antimicrobial peptide transport system, ATPase component:Chromosome segregation ATPases:Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain:HD-GYP domain:Methylase involved in ubiquinone/menaquinone biosynthesis:ABC-type oligopeptide transport system, ATPase component:Cell cycle control, cell division, chromosome partitioning:Amino acid transport and metabolism:Coenzyme transport and metabolism:Lipid transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:Posttranslational modification, protein turnover, chaperones:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:Signal transduction mechanisms:aspS_arch:PhzF_family:thioredoxin:oligo_HPY:tape_meas_TP901:spore_ger_x_C:Defense mechanisms:Toxin production and resistance:Cellular processes and signaling:Poorly characterized:Cellular processes:Amino acids, peptides and amines:Transport and binding proteins:tRNA aminoacylation:Protein synthesis:Electron transport:Energy metabolism:Metabolism:Information storage and processing:Prophage functions:Mobile and extrachromosomal element functions:Sporulation and germination" 221 "Xaa-Pro aminopeptidase:Riboflavin synthase beta-chain:Asp-tRNAAsn/Glu-tRNAGln amidotransferase B subunit (PET112 homolog):Molecular chaperone (small heat shock protein):3,4-dihydroxy-2-butanone 4-phosphate synthase:Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases:Putative translation initiation inhibitor, yjgF family:Riboflavin synthase alpha chain:Molecular chaperone:DnaJ-class molecular chaperone with C-terminal Zn finger domain:Molecular chaperone GrpE (heat shock protein):Uncharacterized conserved protein:3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases:Arginine kinase:Uncharacterized protein with conserved CXXC pairs:Transcriptional repressor of class III stress genes:Amino acid transport and metabolism:Coenzyme transport and metabolism:Lipid transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:Posttranslational modification, protein turnover, chaperones:Function unknown:TIGR00004:lumazine-synth:gatA:gatB:ribE:ribA:DnaJ_bact:prok_dnaK:tRNA aminoacylation:Poorly characterized:Degradation of RNA:Transcription:Protein synthesis:Metabolism:Cellular processes and signaling:Information storage and processing:Riboflavin, FMN, and FAD:Biosynthesis of cofactors, prosthetic groups, and carriers:Protein folding and stabilization:Protein fate" 222 "Energy production and conversion:Glycerol dehydrogenase and related enzymes:ATP-dependent Zn proteases:IMP dehydrogenase/GMP reductase:Uncharacterized conserved protein:Predicted hydrolase (metallo-beta-lactamase superfamily):Gamma-glutamylcysteine synthetase:Nucleotide transport and metabolism:Coenzyme transport and metabolism:Posttranslational modification, protein turnover, chaperones:General function prediction only:Function unknown:tRNA_RlmH_YbeA:FtsH_fam:IMP_dehydrog:glu_cys_ligase:Glutathione and analogs:Biosynthesis of cofactors, prosthetic groups, and carriers:Degradation of proteins, peptides, and glycopeptides:Protein fate:Metabolism:Protein synthesis:Purine ribonucleotide biosynthesis:Purines, pyrimidines, nucleosides, and nucleotides:tRNA and rRNA base modification:Poorly characterized:Cellular processes and signaling" 223 "Energy production and conversion:Diaminopimelate decarboxylase:Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain:Membrane protease subunits, stomatin/prohibitin homologs:Fructose-2,6-bisphosphatase:Cytosine/adenosine deaminases:ABC-type multidrug transport system, ATPase component:Transcriptional regulator:Predicted phosphohydrolases:ABC-type Na+ efflux pump, permease component:Predicted transcriptional regulators:Predicted transcriptional regulators:Predicted transcriptional regulator:Dioxygenases related to 2-nitropropane dioxygenase:AraC-type DNA-binding domain-containing proteins:Methylase involved in ubiquinone/menaquinone biosynthesis:Uncharacterized protein conserved in bacteria:Amino acid transport and metabolism:Nucleotide transport and metabolism:Carbohydrate transport and metabolism:Coenzyme transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:Posttranslational modification, protein turnover, chaperones:Inorganic ion transport and metabolism:General function prediction only:Function unknown:rrf2_super:lysA:GMP_reduct_2:Defense mechanisms:Cellular processes and signaling:Information storage and processing:Aspartate family:Amino acid biosynthesis:Poorly characterized:Unknown function:Nucleotide and nucleoside interconversions:Purines, pyrimidines, nucleosides, and nucleotides:General:Metabolism" 224 "Biotin-(acetyl-CoA carboxylase) ligase:ABC-type dipeptide/oligopeptide/nickel transport systems, permease components:ABC-type cobalt transport system, permease component CbiQ and related transporters:Signal transduction histidine kinase:Cell division protein FtsI/penicillin-binding protein 2:Transcription elongation factor:Predicted transcriptional regulators:UDP-N-acetylmuramate dehydrogenase:ABC-type dipeptide/oligopeptide/nickel transport systems, permease components:Lysyl-tRNA synthetase (class II):Predicted transcriptional regulators:Transcriptional regulators:Predicted ATPase (AAA+ superfamily):Lysophospholipase L1 and related esterases:Predicted N-acetylglucosaminyl transferase:Uncharacterized paraquat-inducible protein B:Predicted multitransmembrane protein:Amino acid transport and metabolism:Carbohydrate transport and metabolism:Coenzyme transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:Cell wall/membrane/envelope biogenesis:Inorganic ion transport and metabolism:General function prediction only:Function unknown:Signal transduction mechanisms:birA_ligase:murB:parB_part:lysS_bact:greA:Rhs_assc_core:Cell envelope:Protein modification and repair:Protein fate:tRNA aminoacylation:Protein synthesis:Transcription factors:Transcription:Metabolism:Poorly characterized:Cellular processes and signaling:Information storage and processing:Biosynthesis and degradation of murein sacculus and peptidoglycan" 225 "Energy production and conversion:Acyl carrier protein:Cytidine deaminase:Predicted Zn-dependent proteases and their inactivated homologs:Ketopantoate hydroxymethyltransferase:UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase:Fe2+/Zn2+ uptake regulation proteins:Methyl-accepting chemotaxis protein:Hydrolases of the alpha/beta superfamily:Phosphomannomutase:Transcriptional regulator:S-adenosylmethionine decarboxylase:DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog:Desulfoferrodoxin:Predicted Zn-dependent hydrolases of the beta-lactamase fold:Endoglucanase:Response regulator containing a CheY-like receiver domain and an HD-GYP domain:Superfamily I DNA and RNA helicases:Acetyl/propionyl-CoA carboxylase, alpha subunit:Flagellar basal body rod protein:Bacterial surface proteins containing Ig-like domains:Amino acid transport and metabolism:Nucleotide transport and metabolism:Carbohydrate transport and metabolism:Coenzyme transport and metabolism:Lipid transport and metabolism:Transcription:Cell wall/membrane/envelope biogenesis:Cell motility:Inorganic ion transport and metabolism:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:Signal transduction mechanisms:panB:neela_ferrous:accC:acyl_carrier:cyt_deam_tetra:sigma70-ECF:SAM_DCase_Eco:FlgEFG_subfam:Purines, pyrimidines, nucleosides, and nucleotides:Biosynthesis:Fatty acid and phospholipid metabolism:Electron transport:Energy metabolism:Polyamine biosynthesis:Central intermediary metabolism:Metabolism:Poorly characterized:Cellular processes and signaling:Information storage and processing:Pantothenate and coenzyme A:Biosynthesis of cofactors, prosthetic groups, and carriers:Salvage of nucleosides and nucleotides" 226 "Energy production and conversion:Guanylate kinase:ABC-type multidrug transport system, permease component:GDP-D-mannose dehydratase:ABC-type multidrug transport system, ATPase component:Isopentenyldiphosphate isomerase:Uncharacterized conserved protein:DNA segregation ATPase FtsK/SpoIIIE and related proteins:Nitrogenase molybdenum-iron protein, alpha and beta chains:Uncharacterized protein conserved in bacteria:NAD+--asparagine ADP-ribosyltransferase:Cell cycle control, cell division, chromosome partitioning:Nucleotide transport and metabolism:Lipid transport and metabolism:Cell wall/membrane/envelope biogenesis:Function unknown:Signal transduction mechanisms:TIGR00159:nifB:gmd:T7_EssCb_Firm:WXG100_ESAT6:Defense mechanisms:Cell envelope:Conserved:Hypothetical proteins:Protein and peptide secretion and trafficking:Protein fate:Nitrogen fixation:Central intermediary metabolism:Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides:Cellular processes and signaling:Metabolism:Poorly characterized" 227 "Fe2+ transport system protein B:Uncharacterized conserved protein:Thioredoxin reductase:ABC-type Fe3+-siderophore transport system, permease component:ABC-type Fe3+-hydroxamate transport system, periplasmic component:ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components:Predicted transcriptional regulators:Transcriptional regulators:Ketopantoate reductase:Fe2+ transport system protein A:Cation transport ATPase:Predicted membrane protein:ABC-type transport system, involved in lipoprotein release, permease component:Coenzyme transport and metabolism:Transcription:Cell wall/membrane/envelope biogenesis:Posttranslational modification, protein turnover, chaperones:Inorganic ion transport and metabolism:Function unknown:TIGR00149_YbjQ:feoB:ATPase_P-type:Cellular processes and signaling:Information storage and processing:Enzymes of unknown specificity:Unknown function:Cations and iron carrying compounds:Transport and binding proteins:Metabolism:Poorly characterized" 228 "Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase:Chorismate synthase:5-enolpyruvylshikimate-3-phosphate synthase:Shikimate 5-dehydrogenase:Prephenate dehydrogenase:ABC-type Co2+ transport system, permease component:3-dehydroquinate synthetase:Cobalamin-5-phosphate synthase:ABC-type Fe3+-hydroxamate transport system, periplasmic component:ABC-type cobalt transport system, permease component CbiQ and related transporters:Shikimate kinase:ABC-type cobalt transport system, ATPase component:Acetyltransferases, including N-acetylases of ribosomal proteins:Cobalamin biosynthesis protein CbiG:3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase:Cobalamin biosynthesis protein CbiK, Co2+ chelatase:Amino acid transport and metabolism:Coenzyme transport and metabolism:Translation, ribosomal structure and biogenesis:Inorganic ion transport and metabolism:aroC:cobS:aroE:cbiO:aroA:aroB:DAHP_synth_Bsub:CbiQ_TIGR:Transport and binding proteins:Information storage and processing:Metabolism:Heme, porphyrin, and cobalamin:Biosynthesis of cofactors, prosthetic groups, and carriers:Aromatic amino acid family:Amino acid biosynthesis:Cations and iron carrying compounds" 229 "Predicted sugar kinase:Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases:5-formyltetrahydrofolate cyclo-ligase:Protein chain release factor A:Predicted metal-dependent hydrolase:Queuine/archaeosine tRNA-ribosyltransferase:Nucleotide-binding protein implicated in inhibition of septum formation:ATPase involved in DNA repair:2-methylthioadenine synthetase:UDP-N-acetylmuramyl pentapeptide synthase:Bacterial cell division membrane protein:S-adenosylmethionine:tRNA-ribosyltransferase-isomerase (queuine synthetase):Diacylglycerol kinase:Deoxyxylulose-5-phosphate synthase:Polyribonucleotide nucleotidyltransferase (polynucleotide phosphorylase):Predicted rRNA methylase:Arginine repressor:Exonuclease VII, large subunit:Holliday junction resolvasome, helicase subunit:Methylase of polypeptide chain release factors:Cell cycle control, cell division, chromosome partitioning:Carbohydrate transport and metabolism:Coenzyme transport and metabolism:Lipid transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:Replication, recombination and repair:Cell wall/membrane/envelope biogenesis:General function prediction only:prfA:TIGR00043:TIGR00089:queA:gatA:maf:dxs:xseA:Q_tRNA_tgt:tly:hemK_fam:recN:ruvB:murF:argR_whole:ftsW:MTHFS_bact:polynuc_phos:General:Unknown function:Cell division:Cellular processes:Protein modification and repair:Protein fate:Translation factors:tRNA and rRNA base modification:tRNA aminoacylation:Other:Thiamine:Degradation of RNA:Transcription:DNA replication, recombination, and repair:Degradation of DNA:DNA metabolism:DNA interactions:Regulatory functions:One-carbon metabolism:Central intermediary metabolism:Protein synthesis:Cell envelope:Biosynthesis and degradation of murein sacculus and peptidoglycan:Information storage and processing:Cellular processes and signaling:Metabolism:Poorly characterized:Biosynthesis of cofactors, prosthetic groups, and carriers" 230 "DNA repair exonuclease:Putative intracellular protease/amidase:Ribose 5-phosphate isomerase RpiB:Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain:Methyl-accepting chemotaxis protein:ABC-type multidrug transport system, permease component:Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases):ABC-type multidrug transport system, ATPase component:ABC-type antimicrobial peptide transport system, ATPase component:Uracil-DNA glycosylase:Uncharacterized protein conserved in bacteria:Predicted phosphosugar isomerases:Predicted membrane protein:NAD+--asparagine ADP-ribosyltransferase:Carbohydrate transport and metabolism:Lipid transport and metabolism:Transcription:Replication, recombination and repair:Cell wall/membrane/envelope biogenesis:Cell motility:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:Function unknown:Signal transduction mechanisms:sbcd:UDG_fam4:spore_ger_x_C:Defense mechanisms:Cellular processes and signaling:Information storage and processing:Sporulation and germination:Poorly characterized:DNA replication, recombination, and repair:DNA metabolism:Cellular processes:Metabolism" 231 "Aspartate-semialdehyde dehydrogenase:Ribonucleotide reductase, alpha subunit:Ribosomal protein L21:Carbonic anhydrase:DNA primase (bacterial type):Fatty acid/phospholipid biosynthesis enzyme:Transcriptional regulator:DNA polymerase III, alpha subunit:ABC-type multidrug transport system, ATPase and permease components:Cold shock proteins:Transcriptional regulator:Predicted phosphohydrolases:Predicted transcriptional regulators:Ketopantoate reductase:Uncharacterized protein conserved in bacteria:Predicted membrane protein:Uncharacterized protein conserved in bacteria:Predicted membrane protein:Bacterial surface proteins containing Ig-like domains:Amino acid transport and metabolism:Nucleotide transport and metabolism:Coenzyme transport and metabolism:Lipid transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:Replication, recombination and repair:Cell motility:Inorganic ion transport and metabolism:General function prediction only:Function unknown:S21p:L21:plsX:lytR_cpsA_psr:polc:apbA_panE:asd_EA:dnaG:NrdJ_Z:yecD_yerC:Defense mechanisms:Purines, pyrimidines, nucleosides, and nucleotides:Biosynthesis:Fatty acid and phospholipid metabolism:Ribosomal proteins: synthesis and modification:Pantothenate and coenzyme A:Information storage and processing:Cellular processes and signaling:Metabolism:Poorly characterized:Aspartate family:Amino acid biosynthesis:General:Unknown function:Biosynthesis of cofactors, prosthetic groups, and carriers:Protein synthesis:DNA replication, recombination, and repair:DNA metabolism:Other:Regulatory functions:2'-Deoxyribonucleotide metabolism" 232 "Ribosomal protein L1:S-adenosylmethionine synthetase:Ribosomal protein L7/L12:Acyl carrier protein:Ribosomal protein L32:Pyrroline-5-carboxylate reductase:Adenine/guanine phosphoribosyltransferases and related PRPP-binding proteins:Preprotein translocase subunit SecE:Predicted transcriptional regulators containing the CopG/Arc/MetJ DNA-binding domain and a metal-binding domain:Enoyl-CoA hydratase/carnithine racemase:Uncharacterized conserved protein:Uncharacterized conserved protein:Predicted transcriptional regulator:Acyl-CoA dehydrogenases:FOG: EAL domain:Growth inhibitor:Amino acid transport and metabolism:Nucleotide transport and metabolism:Coenzyme transport and metabolism:Lipid transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:Secondary metabolites biosynthesis, transport and catabolism:Function unknown:Signal transduction mechanisms:proC:acyl_carrier:rrf2_super:L12:secE_bact:rpmF_bact:metK:rplA_bact:purR_Bsub:Intracellular trafficking, secretion, and vesicular transport:Cellular processes and signaling:Information storage and processing:Glutamate family:Amino acid biosynthesis:General:Unknown function:Protein and peptide secretion and trafficking:Protein fate:Ribosomal proteins: synthesis and modification:Protein synthesis:DNA interactions:Regulatory functions:Biosynthesis:Fatty acid and phospholipid metabolism:Other:Central intermediary metabolism:Metabolism:Poorly characterized" 233 "Cell division GTPase:RecA/RadA recombinase:Metal-dependent proteases with possible chaperone activity:Glutaredoxin and related proteins:Periplasmic protease:Polyribonucleotide nucleotidyltransferase (polynucleotide phosphorylase):ATP-dependent protease Clp, ATPase subunit:Cold shock proteins:Predicted HD superfamily hydrolase:Uncharacterized conserved protein:GAF domain-containing protein:Predicted membrane protein:Predicted hydrolase (metallo-beta-lactamase superfamily):Uncharacterized protein conserved in bacteria:Uncharacterized protein conserved in bacteria:Cell cycle control, cell division, chromosome partitioning:Translation, ribosomal structure and biogenesis:Transcription:Replication, recombination and repair:Cell wall/membrane/envelope biogenesis:Posttranslational modification, protein turnover, chaperones:General function prediction only:Function unknown:Signal transduction mechanisms:ftsZ:prc:HDIG:gcp_kae1:clpX:tigrfam_recA:GlrX_YruB:release_rtcB:polynuc_phos:DNA metabolism:Other:Cellular processes and signaling:Poorly characterized:Cell division:Cellular processes:Protein modification and repair:Degradation of proteins, peptides, and glycopeptides:Protein fate:Information storage and processing:Protein synthesis:Degradation of RNA:Transcription:DNA replication, recombination, and repair" 234 "Queuine/archaeosine tRNA-ribosyltransferase:Fructose-2,6-bisphosphatase:Aspartate/tyrosine/aromatic aminotransferase:Homoserine dehydrogenase:Threonine synthase:Precorrin-3B methylase:ABC-type polysaccharide/polyol phosphate transport system, ATPase component:ABC-type antimicrobial peptide transport system, ATPase component:Primosomal protein N' (replication factor Y) - superfamily II helicase:Aspartyl aminopeptidase:Cobyric acid synthase:NCAIR mutase (PurE)-related proteins:Cobyrinic acid a,c-diamide synthase:Cobalamin biosynthesis protein CbiD:Glycerate kinase:Uncharacterized protein conserved in bacteria:Adenosyl cobinamide kinase/adenosyl cobinamide phosphate guanylyltransferase:Methylase involved in ubiquinone/menaquinone biosynthesis:Precorrin-6B methylase 2:Precorrin-2 methylase:Precorrin-4 methylase:Amino acid transport and metabolism:Carbohydrate transport and metabolism:Coenzyme transport and metabolism:Translation, ribosomal structure and biogenesis:Replication, recombination and repair:Cell wall/membrane/envelope biogenesis:General function prediction only:Function unknown:TIGR00045:thrC:cbiD:cobQ:cobB:Q_tRNA_tgt:priA:cobM_cbiF:cobJ_cbiH:cobI_cbiL:CbiT:ribazole_cobC:Defense mechanisms:Heme, porphyrin, and cobalamin:Biosynthesis of cofactors, prosthetic groups, and carriers:Aspartate family:Amino acid biosynthesis:tRNA and rRNA base modification:Protein synthesis:DNA replication, recombination, and repair:DNA metabolism:Other:Energy metabolism:Information storage and processing:Cellular processes and signaling:Metabolism:Poorly characterized" 235 "Energy production and conversion:Nitrogen regulatory protein PII:Ketopantoate hydroxymethyltransferase:Panthothenate synthetase:Acetyltransferases:UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N-acetylglucosamine-1-phosphate transferase:ATPases involved in chromosome partitioning:FOG: CBS domain:Nitroreductase:Predicted ATPase or kinase:Aspartate 1-decarboxylase:DNA-directed RNA polymerase specialized sigma subunit:ABC-type sugar transport system, periplasmic component:ABC-type sugar transport system, periplasmic component:Uncharacterized protein conserved in bacteria:Bacterial surface proteins containing Ig-like domains:Cell cycle control, cell division, chromosome partitioning:Amino acid transport and metabolism:Carbohydrate transport and metabolism:Coenzyme transport and metabolism:Transcription:Cell wall/membrane/envelope biogenesis:Cell motility:General function prediction only:Function unknown:panC:HI0065_YjeE:panB:panD:eps_fam:rimI:spore_sigG:Carbohydrates, organic alcohols, and acids:Transport and binding proteins:Ribosomal proteins: synthesis and modification:Protein synthesis:Sporulation and germination:Metabolism:Cellular processes and signaling:Information storage and processing:Pantothenate and coenzyme A:Biosynthesis of cofactors, prosthetic groups, and carriers:Enzymes of unknown specificity:Unknown function:Poorly characterized:Cellular processes" 236 "Energy production and conversion:Arginase/agmatinase/formimionoglutamate hydrolase, arginase family:Dihydroxyacid dehydratase/phosphogluconate dehydratase:Glycerophosphoryl diester phosphodiesterase:Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily):Serine/threonine protein phosphatase:Phosphatidylserine decarboxylase:Predicted transcriptional regulators:Methyl-accepting chemotaxis protein:Cobalamin biosynthesis protein CobD/CbiB:Beta-glucosidase-related glycosidases:DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog:Transcriptional regulators:Uncharacterized conserved protein:H+/gluconate symporter and related permeases:Predicted enzyme related to lactoylglutathione lyase:Uncharacterized protein conserved in bacteria:Predicted DNA-binding protein with the Helix-hairpin-helix motif:Amino acid transport and metabolism:Carbohydrate transport and metabolism:Coenzyme transport and metabolism:Lipid transport and metabolism:Transcription:Cell motility:General function prediction only:Function unknown:Signal transduction mechanisms:cobD:gntP:rocF_arginase:TIGR02271:sigma70-ECF:SAM_7_link_chp:rSAM_link_UDG:Enzymes of unknown specificity:Unknown function:Carbohydrates, organic alcohols, and acids:Transport and binding proteins:Metabolism:Poorly characterized:Cellular processes and signaling:Information storage and processing:Heme, porphyrin, and cobalamin:Biosynthesis of cofactors, prosthetic groups, and carriers" 237 "Energy production and conversion:Ribosomal protein S12:Ribosomal protein S7:Ribosomal protein L2:Ribosomal protein L22:Ribosomal protein L13:Ribosomal protein S9:Ribosomal protein S19:Translation elongation factor Ts:Ribosomal protein L19:CTP synthase (UTP-ammonia lyase):Fe-S oxidoreductase:Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific:Ribosomal protein HS6-type (S12/L30/L7a):Predicted integral membrane protein:Nucleotide transport and metabolism:Carbohydrate transport and metabolism:Translation, ribosomal structure and biogenesis:Function unknown:tsf:PyrG:EIIB_glc:rpsL_bact:rplS_bact:rpsG_bact:rplV_bact:rpsS_bact:rplM_bact:rplB_bact:rSAM_fuse_unch:Enzymes of unknown specificity:Unknown function:Translation factors:Poorly characterized:Protein synthesis:Pyrimidine ribonucleotide biosynthesis:Purines, pyrimidines, nucleosides, and nucleotides:Ribosomal proteins: synthesis and modification:Metabolism:Information storage and processing:PTS:Signal transduction" 238 "Energy production and conversion:Purine nucleoside phosphorylase:Aspartyl/asparaginyl-tRNA synthetases:Ribonucleotide reductase, alpha subunit:(acyl-carrier-protein) S-malonyltransferase:Glycerol dehydrogenase and related enzymes:Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily):Aspartate ammonia-lyase:Nicotinic acid mononucleotide adenylyltransferase:Transcriptional regulator:Cellulase M and related proteins:Predicted membrane protein:Transcriptional regulators:Carbon starvation protein, predicted membrane protein:Uncharacterized conserved protein:Uncharacterized protein conserved in bacteria:Predicted double-stranded RNA/RNA-DNA hybrid binding protein:Uncharacterized protein conserved in bacteria:Capsular polysaccharide biosynthesis protein:Predicted membrane protein:Amino acid transport and metabolism:Nucleotide transport and metabolism:Carbohydrate transport and metabolism:Coenzyme transport and metabolism:Lipid transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:Cell wall/membrane/envelope biogenesis:General function prediction only:Function unknown:Signal transduction mechanisms:cyt_tran_rel:lytR_cpsA_psr:aspS_arch:PNPH-PUNA-XAPA:NrdJ_Z:xxxLxxG_by_4:Protein synthesis:Other:Regulatory functions:2'-Deoxyribonucleotide metabolism:Purines, pyrimidines, nucleosides, and nucleotides:Metabolism:Poorly characterized:Cellular processes and signaling:Information storage and processing:tRNA aminoacylation" 239 "Energy production and conversion:Predicted S-adenosylmethionine-dependent methyltransferase involved in cell envelope biogenesis:Predicted hydrolase of the metallo-beta-lactamase superfamily:Predicted phosphatase/phosphohexomutase:Predicted unusual protein kinase:1-deoxy-D-xylulose 5-phosphate reductoisomerase:Membrane carboxypeptidase (penicillin-binding protein):Nucleoside phosphorylase:Acetyl-CoA carboxylase beta subunit:NAD-dependent aldehyde dehydrogenases:dTDP-D-glucose 4,6-dehydratase:Transcription termination factor:Peroxiredoxin:Uncharacterized protein conserved in bacteria:DnaK suppressor protein:Transcriptional regulators:FOG: GGDEF domain:Predicted Zn-dependent hydrolases of the beta-lactamase fold:Uncharacterized protein conserved in bacteria:ABC-type oligopeptide transport system, periplasmic component:Amino acid transport and metabolism:Nucleotide transport and metabolism:Lipid transport and metabolism:Transcription:Cell wall/membrane/envelope biogenesis:Posttranslational modification, protein turnover, chaperones:General function prediction only:Function unknown:Signal transduction mechanisms:TIGR00006:Dxr:GGDEF:accD:MG423:rho:dTDP_gluc_dehyt:HAD-SF-IA-v3:MTA/SAH-Nsdase:PBP_1a_fam:spore_yteA:Information storage and processing:Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides:Biosynthesis and degradation of murein sacculus and peptidoglycan:Cell envelope:Other:Signal transduction:Other:Biosynthesis of cofactors, prosthetic groups, and carriers:Enzymes of unknown specificity:Unknown function:Poorly characterized:Hypothetical proteins:Sporulation and germination:Cellular processes:Transcription factors:Transcription:Salvage of nucleosides and nucleotides:Purines, pyrimidines, nucleosides, and nucleotides:Biosynthesis:Fatty acid and phospholipid metabolism:Conserved:Metabolism:Cellular processes and signaling" 240 "Energy production and conversion:Methylated DNA-protein cysteine methyltransferase:Nucleoside-diphosphate-sugar epimerases:Transcriptional regulator:cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases:Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain:Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases):Glycosyltransferases, probably involved in cell wall biogenesis:Predicted transcriptional regulators:Formate/nitrite family of transporters:Dissimilatory sulfite reductase (desulfoviridin), alpha and beta subunits:Nitrate/nitrite transporter:Predicted aminopeptidases:Permeases of the major facilitator superfamily:Arabinose efflux permease:Predicted nucleotidyltransferase:Predicted integral membrane protein:Carbohydrate transport and metabolism:Lipid transport and metabolism:Transcription:Replication, recombination and repair:Cell wall/membrane/envelope biogenesis:Inorganic ion transport and metabolism:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:Function unknown:Signal transduction mechanisms:ogt:2A0309:kduD:sulfite_red_A:sulfite_red_C:glyc2_xrt_Gpos1:6_pyr_pter_rel:Rhs_assc_core:DNA metabolism:Biosynthesis and degradation of polysaccharides:Energy metabolism:Sulfur metabolism:Central intermediary metabolism:Cellular processes and signaling:Poorly characterized:Metabolism:Information storage and processing:Amino acids, peptides and amines:Transport and binding proteins:DNA replication, recombination, and repair" 241 "Ribosomal protein L5:Ribonucleotide reductase, beta subunit:NAD/FAD-utilizing enzyme apparently involved in cell division:Translation elongation factors (GTPases):Biotin synthase and related enzymes:Predicted phosphatase/phosphohexomutase:Predicted thioesterase:Adenine deaminase:ABC-type antimicrobial peptide transport system, ATPase component:Predicted Fe-S oxidoreductase:Transcriptional regulator:Transcriptional regulators:Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain:AraC-type DNA-binding domain-containing proteins:Predicted signal transduction protein with a C-terminal ATPase domain:Uncharacterized protein conserved in bacteria:Uncharacterized conserved protein:Cell cycle control, cell division, chromosome partitioning:Nucleotide transport and metabolism:Coenzyme transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:General function prediction only:Function unknown:Signal transduction mechanisms:TIGR00051:gidA:small_GTP:ade:TIGR01212:HAD-SF-IA-v3:rSAM_HydE:Defense mechanisms:Metabolism:Cellular processes and signaling:Information storage and processing:General:Enzymes of unknown specificity:Unknown function:Protein modification and repair:Protein fate:tRNA and rRNA base modification:Protein synthesis:Salvage of nucleosides and nucleotides:Purines, pyrimidines, nucleosides, and nucleotides:Poorly characterized" 242 "Pyruvate kinase:Serine/threonine protein kinase:Glycosyltransferases, probably involved in cell wall biogenesis:Uncharacterized protein conserved in bacteria:Carbohydrate transport and metabolism:Transcription:Replication, recombination and repair:Cell wall/membrane/envelope biogenesis:General function prediction only:Function unknown:Signal transduction mechanisms:pyruv_kin:WXG100_ESAT6:Cellular processes and signaling:Metabolism:Information storage and processing:Glycolysis/gluconeogenesis:Energy metabolism:Poorly characterized" 243 "Guanylate kinase:Peptide methionine sulfoxide reductase:Replicative DNA helicase:Ribosomal protein L9:ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components:Predicted xylanase/chitin deacetylase:Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain:Predicted Zn-dependent peptidases, insulinase-like:Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases):DNA uptake protein and related DNA-binding proteins:Uncharacterized conserved protein:Nucleotide transport and metabolism:Carbohydrate transport and metabolism:Lipid transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:Replication, recombination and repair:Posttranslational modification, protein turnover, chaperones:Inorganic ion transport and metabolism:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:Function unknown:Signal transduction mechanisms:L9:TIGR00159:msrA:DnaB:3oxo_ACP_reduc:spore_pdaA:Poorly characterized:Metabolism:Cellular processes and signaling:Information storage and processing:Ribosomal proteins: synthesis and modification:Protein synthesis:DNA replication, recombination, and repair:DNA metabolism:Biosynthesis:Fatty acid and phospholipid metabolism:Hypothetical proteins:Conserved:Sporulation and germination:Adaptations to atypical conditions:Cellular processes" 244 "Ribonucleotide reductase, alpha subunit:Molecular chaperone, HSP90 family:3-oxoacyl-[acyl-carrier-protein] synthase III:FOG: Ankyrin repeat:Predicted xylanase/chitin deacetylase:Metal-dependent amidase/aminoacylase/carboxypeptidase:Septum formation inhibitor-activating ATPase:Cell cycle control, cell division, chromosome partitioning:Nucleotide transport and metabolism:Carbohydrate transport and metabolism:Lipid transport and metabolism:Posttranslational modification, protein turnover, chaperones:General function prediction only:amidohydrolases:minD_bact:NrdE_NrdA:CxxC_CxxC_SSSS:Cell division:Cellular processes:Degradation of proteins, peptides, and glycopeptides:Protein fate:Poorly characterized:Regulatory functions:2'-Deoxyribonucleotide metabolism:Purines, pyrimidines, nucleosides, and nucleotides:DNA interactions:Metabolism:Cellular processes and signaling" 245 "ABC-type phosphate transport system, periplasmic component:ABC-type phosphate transport system, permease component:ABC-type phosphate transport system, permease component:Predicted ATPase with chaperone activity:Predicted sugar phosphate isomerase involved in capsule formation:ABC-type phosphate transport system, ATPase component:Pyruvate-formate lyase-activating enzyme:Acyl carrier protein phosphodiesterase:Predicted DNA-binding proteins:DNA uptake protein and related DNA-binding proteins:Uncharacterized protein conserved in bacteria:Lipid transport and metabolism:Replication, recombination and repair:Cell wall/membrane/envelope biogenesis:Posttranslational modification, protein turnover, chaperones:Inorganic ion transport and metabolism:General function prediction only:Function unknown:TIGR00368:2A0309:3a0107s01c2:3a0107s02c:ptsS_2:phosphate_pstC:RuMP_HxlB:Unknown function:Poorly characterized:Cellular processes and signaling:Information storage and processing:General:Metabolism:Anions:Amino acids, peptides and amines:Transport and binding proteins" 246 "Mg-dependent DNase:Tyrosyl-tRNA synthetase:Predicted amidohydrolase:ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components:Phosphomannomutase:ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component:Nicotinic acid phosphoribosyltransferase:Membrane transporters of cations and cationic drugs:Glycopeptide antibiotics resistance protein:Carbohydrate transport and metabolism:Coenzyme transport and metabolism:Translation, ribosomal structure and biogenesis:Replication, recombination and repair:Inorganic ion transport and metabolism:General function prediction only:tyrS:nadE:glmM:NAPRTase_put:Defense mechanisms:Protein synthesis:Amino sugars:Central intermediary metabolism:Pyridine nucleotides:Metabolism:Cellular processes and signaling:Information storage and processing:Poorly characterized:Biosynthesis of cofactors, prosthetic groups, and carriers:tRNA aminoacylation" 247 "Tryptophanyl-tRNA synthetase:Mismatch repair ATPase (MutS family):Dihydrofolate reductase:Zn-dependent hydrolases, including glyoxylases:Type I site-specific restriction-modification system, R (restriction) subunit and related helicases:Predicted transcriptional regulators:Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain:FOG: CheY-like receiver:2-keto-3-deoxy-6-phosphogluconate aldolase:Predicted metal-dependent membrane protease:Transcriptional regulator:Uncharacterized proteins of the AP superfamily:Transposase and inactivated derivatives:4-diphosphocytidyl-2C-methyl-D-erythritol 2-phosphate synthase:Regulators of stationary/sporulation gene expression:Regulator of polyketide synthase expression:Carbohydrate transport and metabolism:Coenzyme transport and metabolism:Lipid transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:Replication, recombination and repair:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:Signal transduction mechanisms:ispE:trpS:HDIG:eda:lp_hng_hel_AbrB:hyd_TM1266:Defense mechanisms:Biosynthesis of cofactors, prosthetic groups, and carriers:tRNA aminoacylation:Protein synthesis:Poorly characterized:Regulatory functions:Entner-Doudoroff:Energy metabolism:DNA interactions:Metabolism:Cellular processes and signaling:Information storage and processing:Other" 248 "Energy production and conversion:Nitroreductase:Superfamily I DNA and RNA helicases and helicase subunits:ABC-type multidrug transport system, ATPase component:Transcriptional regulator:Predicted transcriptional regulators:Beta-lactamase class C and other penicillin binding proteins:Predicted HD superfamily hydrolase involved in NAD metabolism:Putative protein-S-isoprenylcysteine methyltransferase:Type II secretory pathway, pseudopilin PulG:HD-GYP domain:Putative peptidoglycan-binding domain-containing protein:L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily:Bacterial surface proteins containing Ig-like domains:Coenzyme transport and metabolism:Transcription:Replication, recombination and repair:Cell wall/membrane/envelope biogenesis:Cell motility:Posttranslational modification, protein turnover, chaperones:General function prediction only:Signal transduction mechanisms:lytR_cpsA_psr:TIGR00488:IV_pilin_GFxxxE:Intracellular trafficking, secretion, and vesicular transport:Defense mechanisms:Cellular processes and signaling:Information storage and processing:Enzymes of unknown specificity:Unknown function:Metabolism:Protein fate:Other:Regulatory functions:Poorly characterized:Protein and peptide secretion and trafficking" 249 "Glutamine phosphoribosylpyrophosphate amidotransferase:Phosphoribosylformylglycinamidine (FGAM) synthase, synthetase domain:AICAR transformylase/IMP cyclohydrolase PurH (only IMP cyclohydrolase domain in Aful):Phosphoribosylamine-glycine ligase:GTP cyclohydrolase I:Di- and tricarboxylate transporters:ATPase components of ABC transporters with duplicated ATPase domains:Organic radical activating enzymes:ABC-type multidrug transport system, ATPase and permease components:Predicted inhibitor of MCP methylation, homolog of CheC:Benzoyl-CoA reductase/2-hydroxyglutaryl-CoA dehydratase subunit, BcrC/BadD/HgdB:Amino acid transport and metabolism:Nucleotide transport and metabolism:Coenzyme transport and metabolism:Cell motility:Posttranslational modification, protein turnover, chaperones:Inorganic ion transport and metabolism:General function prediction only:folE:purH:dass:purD:purF:FGAM-synthase:rSAM_QueE_Clost:Defense mechanisms:Transport and binding proteins:tRNA and rRNA base modification:Protein synthesis:Purine ribonucleotide biosynthesis:Purines, pyrimidines, nucleosides, and nucleotides:Cations and iron carrying compounds:Biosynthesis of cofactors, prosthetic groups, and carriers:Folic acid:Cellular processes and signaling:Metabolism:Poorly characterized" 250 "Phosphoribosylcarboxyaminoimidazole (NCAIR) mutase:Serine-pyruvate aminotransferase/archaeal aspartate aminotransferase:Phosphoglycerate dehydrogenase and related dehydrogenases:Isopropylmalate/homocitrate/citramalate synthases:Phosphoribosylaminoimidazole (AIR) synthetase:Phosphoribosylaminoimidazolesuccinocarboxamide (SAICAR) synthase:Seryl-tRNA synthetase:Folate-dependent phosphoribosylglycinamide formyltransferase PurN:Carbamoylphosphate synthase large subunit (split gene in MJ):Carbamoylphosphate synthase small subunit:6-pyruvoyl-tetrahydropterin synthase:Uncharacterized conserved protein:Amino acid transport and metabolism:Nucleotide transport and metabolism:Coenzyme transport and metabolism:Translation, ribosomal structure and biogenesis:Function unknown:purC:serS:PurN:purM:leuA_yeast:purE:CPSaseIIsmall:CPSaseII_lrg:queuosine_QueD:Pyrimidine ribonucleotide biosynthesis:Metabolism:Purines, pyrimidines, nucleosides, and nucleotides:Purine ribonucleotide biosynthesis:Poorly characterized:Information storage and processing:Pyruvate family:Amino acid biosynthesis:tRNA and rRNA base modification:tRNA aminoacylation:Protein synthesis" 251 "Phosphoribosylpyrophosphate synthetase:Superfamily II DNA and RNA helicases:Signal recognition particle GTPase:Predicted hydrolases of the HAD superfamily:Parvulin-like peptidyl-prolyl isomerase:Uncharacterized low-complexity proteins:Uncharacterized stress-induced protein:Predicted membrane-bound metal-dependent hydrolases:DNA repair proteins:Sugar phosphate permease:Endoglucanase:Uncharacterized protein conserved in bacteria:Uncharacterized conserved protein:Beta-mannanase:Capsular polysaccharide biosynthesis protein:Pleiotropic transcriptional repressor:Uncharacterized protein conserved in bacteria:Amino acid transport and metabolism:Nucleotide transport and metabolism:Carbohydrate transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:Replication, recombination and repair:Cell wall/membrane/envelope biogenesis:Posttranslational modification, protein turnover, chaperones:General function prediction only:Function unknown:Cof-subfamily:TIGR00255:radc:efflux_EmrB:ffh:ribP_PPkin:codY_Gpos:WXG100_ESAT6:Intracellular trafficking, secretion, and vesicular transport:DNA interactions:Regulatory functions:Purine ribonucleotide biosynthesis:Purines, pyrimidines, nucleosides, and nucleotides:Transport and binding proteins:Cellular processes and signaling:Metabolism:Poorly characterized:Enzymes of unknown specificity:Unknown function:Conserved:Hypothetical proteins:Other:Information storage and processing:Protein and peptide secretion and trafficking:Protein fate:DNA replication, recombination, and repair:DNA metabolism" 252 "Energy production and conversion:Na+-driven multidrug efflux pump:Uncharacterized membrane protein, putative virulence factor:3-dehydroquinate dehydratase II:UDP-N-acetylmuramyl tripeptide synthase:Transcription elongation factor:Na+/H+ antiporter:Transcriptional regulators:AraC-type DNA-binding domain-containing proteins:Signal transduction histidine kinase:Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain:Predicted multitransmembrane protein:Amino acid transport and metabolism:Transcription:Cell wall/membrane/envelope biogenesis:General function prediction only:Function unknown:Signal transduction mechanisms:GGDEF:matE:murE:aroQ:greA:Defense mechanisms:Other:Cellular processes and signaling:Information storage and processing:Signal transduction:Aromatic amino acid family:Amino acid biosynthesis:Other:Transport and binding proteins:Transcription factors:Transcription:Biosynthesis and degradation of murein sacculus and peptidoglycan:Poorly characterized:Metabolism:Cell envelope" 253 "Replicative DNA helicase:Thiamine monophosphate synthase:Organic radical activating enzymes:Signal transduction histidine kinase:Carbonic anhydrases/acetyltransferases, isoleucine patch superfamily:Permeases of the drug/metabolite transporter (DMT) superfamily:Predicted xylanase/chitin deacetylase:Predicted Fe-S-cluster redox enzyme:ABC-type cobalt transport system, ATPase component:ABC-type multidrug transport system, ATPase and permease components:Oxygen-sensitive ribonucleoside-triphosphate reductase:Hemerythrin:Uncharacterized vancomycin resistance protein:Uncharacterized protein with conserved CXXC pairs:Antirepressor regulating drug resistance, predicted signal transduction N-terminal membrane component:Amino acid transport and metabolism:Nucleotide transport and metabolism:Carbohydrate transport and metabolism:Coenzyme transport and metabolism:Transcription:Replication, recombination and repair:Posttranslational modification, protein turnover, chaperones:Inorganic ion transport and metabolism:General function prediction only:Function unknown:Signal transduction mechanisms:thiE:YD_repeat_2x:hemeryth_dom:NrdD:NrdG:Defense mechanisms:Thiamine:Biosynthesis of cofactors, prosthetic groups, and carriers:Protein modification and repair:Poorly characterized:2'-Deoxyribonucleotide metabolism:Purines, pyrimidines, nucleosides, and nucleotides:Protein fate:Metabolism:Cellular processes and signaling:Information storage and processing" 254 "Energy production and conversion:Ribosomal protein S12:Ribosomal protein S7:Mg-dependent DNase:Ribosomal protein L3:Ribosomal protein L2:Ribosomal protein L13:Adenylosuccinate synthase:Predicted S-adenosylmethionine-dependent methyltransferase involved in bacterial cell division:Orotate phosphoribosyltransferase:Membrane GTPase LepA:ATPases involved in chromosome partitioning:CTP synthase (UTP-ammonia lyase):Na+-driven multidrug efflux pump:Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family:Putative intracellular protease/amidase:Fe-S oxidoreductase:Ferredoxin:Ribosomal protein HS6-type (S12/L30/L7a):Phosphotransferase system IIA components:SAM-dependent methyltransferases related to tRNA (uracil-5-)-methyltransferase:Uncharacterized protein conserved in bacteria:Predicted integral membrane protein:Cell cycle control, cell division, chromosome partitioning:Nucleotide transport and metabolism:Carbohydrate transport and metabolism:Translation, ribosomal structure and biogenesis:Replication, recombination and repair:Cell wall/membrane/envelope biogenesis:Posttranslational modification, protein turnover, chaperones:General function prediction only:Function unknown:TIGR00010:gidB:purA:small_GTP:pyrE:PyrG:rumA:matE:PTBA:rpsL_bact:rpsG_bact:rplM_bact:rplB_bact:PfpI:L3_bact:sam_1_link_chp:rSAM_fuse_unch:Defense mechanisms:Unknown function:Other:Transport and binding proteins:Degradation of proteins, peptides, and glycopeptides:Protein fate:tRNA and rRNA base modification:Ribosomal proteins: synthesis and modification:Protein synthesis:Pyrimidine ribonucleotide biosynthesis:Purine ribonucleotide biosynthesis:Purines, pyrimidines, nucleosides, and nucleotides:Enzymes of unknown specificity:General:Signal transduction:PTS:Information storage and processing:Cellular processes and signaling:Metabolism:Poorly characterized" 255 "Energy production and conversion:DNA-directed RNA polymerase, beta subunit/140 kD subunit:DNA-directed RNA polymerase, beta' subunit/160 kD subunit:Ribosomal protein L3:Ribosomal protein L23:Ribosomal protein L6P/L9E:Ribosomal protein S13:Pseudouridylate synthase:Ribosomal protein S19:Ribosomal protein L24:Transcription antiterminator:Ribosomal protein L29:Dihydrofolate reductase:Ribosomal protein L33:Translation initiation factor 1 (IF-1):Actin-like ATPase involved in cell morphogenesis:Phosphoenolpyruvate-protein kinase (PTS system EI component in bacteria):ABC-type cobalt transport system, ATPase component:N-acetylglucosamine-1-phosphate uridyltransferase (contains nucleotidyltransferase and I-patch acetyltransferase domains):Acyl-CoA dehydrogenases:Electron transfer flavoprotein, beta subunit:Ribosomal protein L14E/L6E/L27E:Cell cycle control, cell division, chromosome partitioning:Carbohydrate transport and metabolism:Coenzyme transport and metabolism:Lipid transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:Cell wall/membrane/envelope biogenesis:Inorganic ion transport and metabolism:infA:L29:hisT_truA:mreB:nusG:rpmG_bact:rpsS_bact:rplX_bact:glmU:PTS_I_fam:rpoB:rpoC_TIGR:L3_bact:bact_S13:L6_bact:Amino sugars:Metabolism:Information storage and processing:Biosynthesis and degradation of murein sacculus and peptidoglycan:Cell envelope:Translation factors:tRNA and rRNA base modification:Ribosomal proteins: synthesis and modification:Protein synthesis:Transcription factors:DNA-dependent RNA polymerase:Transcription:Cellular processes and signaling:Central intermediary metabolism" 256 "Putative translation factor (SUA5):tRNA-dihydrouridine synthase:Mg-dependent DNase:Phosphoglycerate dehydrogenase and related dehydrogenases:4-aminobutyrate aminotransferase and related aminotransferases:Homoserine dehydrogenase:Threonine synthase:Predicted GTPase:DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32):ABC-type amino acid transport system, permease component:Methyl-accepting chemotaxis protein:Predicted RNA-binding protein containing KH domain, possibly ribosomal protein:N-Dimethylarginine dimethylaminohydrolase:Hydroxyethylthiazole kinase, sugar kinase family:Putative NADPH-quinone reductase (modulator of drug activity B):Type II secretory pathway, ATPase PulE/Tfp pilus assembly pathway, ATPase PilB:Methylase of polypeptide chain release factors:Predicted metal-dependent enzyme:Arginine degradation protein (predicted deacylase):Uncharacterized protein conserved in bacteria:Amino acid transport and metabolism:Coenzyme transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:Replication, recombination and repair:Cell motility:General function prediction only:Function unknown:Signal transduction mechanisms:TIGR00010:TIGR00057:small_GTP:thrC:hemK_fam:GABAtrnsam:nifR3_yhdG:HEQRo_perm_3TM:RpoD_Cterm:Intracellular trafficking, secretion, and vesicular transport:Poorly characterized:Protein fate:Transcription factors:Transcription:Other:Central intermediary metabolism:Protein modification and repair:Metabolism:Cellular processes and signaling:Information storage and processing:Aspartate family:Amino acid biosynthesis:General:Enzymes of unknown specificity:Unknown function:Amino acids, peptides and amines:Transport and binding proteins" 257 "Transcriptional regulator:Predicted phosphohydrolases:Uncharacterized protein conserved in bacteria:Uncharacterized conserved protein:Transcription:General function prediction only:Function unknown:Information storage and processing:Poorly characterized" 258 "Predicted N6-adenine-specific DNA methylase:Aspartate-semialdehyde dehydrogenase:Thymidylate synthase:Ribonucleotide reductase, alpha subunit:Dihydrofolate reductase:Putative intracellular protease/amidase:Methyl-accepting chemotaxis protein:Predicted membrane protein:Histidinol phosphatase and related hydrolases of the PHP family:Predicted transcriptional regulators:Uncharacterized proteins of the AP superfamily:Ribonucleases G and E:FOG: FHA domain:Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain:Uncharacterized protein conserved in bacteria:Signal transduction histidine kinase:Uncharacterized protein conserved in bacteria:Uncharacterized conserved protein:Endopolygalacturonase:Amino acid transport and metabolism:Nucleotide transport and metabolism:Coenzyme transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:Replication, recombination and repair:Cell wall/membrane/envelope biogenesis:Cell motility:General function prediction only:Function unknown:Signal transduction mechanisms:RNaseEG:yihY_not_rbn:asd_EA:PfpI:NrdE_NrdA:thym_sym:T7_EssCb_Firm:WXG100_ESAT6:Unknown function:Degradation of proteins, peptides, and glycopeptides:Protein and peptide secretion and trafficking:Protein fate:Degradation of RNA:Transcription:2'-Deoxyribonucleotide metabolism:Purines, pyrimidines, nucleosides, and nucleotides:Metabolism:Poorly characterized:Cellular processes and signaling:Information storage and processing:Aspartate family:Amino acid biosynthesis:General" 259 "Energy production and conversion:NTP pyrophosphohydrolases including oxidative damage repair enzymes:Superfamily II DNA/RNA helicases, SNF2 family:Predicted permease:Methionine synthase I (cobalamin-dependent), methyltransferase domain:ABC-type multidrug transport system, permease component:Transcriptional regulator:Highly conserved protein containing a thioredoxin domain:DNA polymerase III, delta subunit:Transcriptional regulators:Rubredoxin:Electron transfer flavoprotein, beta subunit:Predicted signal transduction protein with a C-terminal ATPase domain:Response regulator of the LytR/AlgR family:Acyl-ACP thioesterase:Spore coat protein:Amino acid transport and metabolism:Lipid transport and metabolism:Transcription:Replication, recombination and repair:Cell wall/membrane/envelope biogenesis:Posttranslational modification, protein turnover, chaperones:General function prediction only:Signal transduction mechanisms:holA:hyd_TM1266:Defense mechanisms:Metabolism:Cellular processes and signaling:Information storage and processing:Poorly characterized:DNA metabolism:DNA interactions:Regulatory functions:DNA replication, recombination, and repair" 260 "Energy production and conversion:Ribosomal protein L28:Ribosomal protein S16:Phosphotransacetylase:Thioredoxin reductase:Gamma-aminobutyrate permease and related permeases:3-hydroxyacyl-CoA dehydrogenase:Predicted RNA-binding protein (contains KH domain):Homoserine trans-succinylase:Phosphotransferase system, HPr-related proteins:Uncharacterized bacitracin resistance protein:Growth inhibitor:Butyrate kinase:Uncharacterized protein conserved in bacteria:Amino acid transport and metabolism:Carbohydrate transport and metabolism:Lipid transport and metabolism:Translation, ribosomal structure and biogenesis:Posttranslational modification, protein turnover, chaperones:General function prediction only:Function unknown:Signal transduction mechanisms:S16:L28:undec_PP_bacA:metA:PTS_HPr_family:thioredoxin:P_butyryltrans:butyr_kinase:TIGR03905_4_Cys:Defense mechanisms:Cellular processes and signaling:Information storage and processing:Biosynthesis and degradation of murein sacculus and peptidoglycan:Cell envelope:PTS:Signal transduction:Aspartate family:Amino acid biosynthesis:General:Unknown function:Ribosomal proteins: synthesis and modification:Protein synthesis:Fermentation:Electron transport:Energy metabolism:Metabolism:Poorly characterized" 261 "Energy production and conversion:Dimethyladenosine transferase (rRNA methylation):Aspartate/tyrosine/aromatic aminotransferase:Predicted phosphatases:Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily):Signal transduction histidine kinase:Predicted xylanase/chitin deacetylase:Fe-S oxidoreductases:Transcriptional regulators:Pyridoxal/pyridoxine/pyridoxamine kinase:Endoglucanase:Predicted flavin-nucleotide-binding protein:Leucine-rich repeat (LRR) protein:Amino acid transport and metabolism:Carbohydrate transport and metabolism:Coenzyme transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:General function prediction only:Function unknown:Signal transduction mechanisms:ksgA:HAD-SF-IA-v1:Metabolism:Cellular processes and signaling:Information storage and processing:Enzymes of unknown specificity:Unknown function:tRNA and rRNA base modification:Protein synthesis:Poorly characterized" 262 "ABC-type Co2+ transport system, permease component:Na+-driven multidrug efflux pump:Permeases of the drug/metabolite transporter (DMT) superfamily:Cell wall-associated hydrolases (invasion-associated proteins):Transcriptional regulator:Predicted HD superfamily hydrolase:D-alanyl-D-alanine carboxypeptidase:Threonine aldolase:Uncharacterized conserved protein:Phosphopantetheinyl transferase:Permeases:Predicted membrane protein:Predicted membrane protein:Amino acid transport and metabolism:Carbohydrate transport and metabolism:Coenzyme transport and metabolism:Transcription:Cell wall/membrane/envelope biogenesis:Inorganic ion transport and metabolism:General function prediction only:Function unknown:TIGR00266:pantethn_trn:matE:Defense mechanisms:Cellular processes and signaling:Information storage and processing:Conserved:Hypothetical proteins:Other:Transport and binding proteins:Protein modification and repair:Protein fate:Metabolism:Poorly characterized" 263 "Glutamate synthase domain 2:Membrane proteins related to metalloendopeptidases:Uncharacterized protein conserved in bacteria:Uncharacterized conserved protein:Activator of 2-hydroxyglutaryl-CoA dehydratase (HSP70-class ATPase domain):Sporulation protein and related proteins:Uncharacterized protein conserved in bacteria:Uncharacterized protein conserved in bacteria:Uncharacterized protein conserved in bacteria:Bacterial surface proteins containing Ig-like domains:Cell cycle control, cell division, chromosome partitioning:Amino acid transport and metabolism:Lipid transport and metabolism:Cell wall/membrane/envelope biogenesis:Cell motility:Function unknown:CoA_E_activ:SpoIID_LytB:spore_III_AE:spore_III_D:spore_III_AD:spore_III_AA:spore_III_AF:Sporulation and germination:Metabolism:Cellular processes and signaling:General:Unknown function:Poorly characterized:Cellular processes" 264 "ATPases involved in chromosome partitioning:Serine/threonine protein kinase:Uncharacterized low-complexity proteins:Beta-mannanase:Predicted membrane protein:Uncharacterized protein conserved in bacteria:Cell cycle control, cell division, chromosome partitioning:Carbohydrate transport and metabolism:Transcription:Replication, recombination and repair:General function prediction only:Function unknown:Signal transduction mechanisms:WXG100_ESAT6:Poorly characterized:Metabolism:Cellular processes and signaling:Information storage and processing" 265 "Energy production and conversion:FAD/FMN-containing dehydrogenases:Methylated DNA-protein cysteine methyltransferase:Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases:Signal transduction histidine kinase:Predicted transcriptional regulators:Amino acid transporters:Lactate dehydrogenase and related dehydrogenases:Acetyltransferases, including N-acetylases of ribosomal proteins:K+-transporting ATPase, A chain:Uncharacterized conserved protein related to pyruvate formate-lyase activating enzyme:K+-transporting ATPase, c chain:2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase:Leucine-rich repeat (LRR) protein:Amino acid transport and metabolism:Nucleotide transport and metabolism:Carbohydrate transport and metabolism:Coenzyme transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:Replication, recombination and repair:Inorganic ion transport and metabolism:General function prediction only:Function unknown:Signal transduction mechanisms:ogt:kdpA:kdpC:spore_V_AD:spore_yqfC:spore_yqfD:Cellular processes:Cations and iron carrying compounds:Transport and binding proteins:DNA replication, recombination, and repair:DNA metabolism:Metabolism:Poorly characterized:Cellular processes and signaling:Information storage and processing:Sporulation and germination" 266 "Energy production and conversion:Acetyltransferase (isoleucine patch superfamily):Pyridoxine biosynthesis enzyme:Glutathione peroxidase:Na+-driven multidrug efflux pump:Transcriptional regulator:Flavodoxins:Nitroreductase:Membrane protein TerC, possibly involved in tellurium resistance:ABC-type multidrug transport system, ATPase component:ABC-type dipeptide/oligopeptide/nickel transport systems, permease components:N-acetylglutamate synthase (N-acetylornithine aminotransferase):Fe2+ transport system protein A:Pyrimidine reductase, riboflavin biosynthesis:Predicted membrane protein:Uncharacterized protein conserved in bacteria:Amino acid transport and metabolism:Coenzyme transport and metabolism:Transcription:Posttranslational modification, protein turnover, chaperones:Inorganic ion transport and metabolism:General function prediction only:Function unknown:ArgJ:ribD_Cterm:TIGR00343:matE:flav_short:R_switched_YjbE:Defense mechanisms:Biosynthesis of cofactors, prosthetic groups, and carriers:Glutamate family:Amino acid biosynthesis:Other:Transport and binding proteins:Electron transport:Energy metabolism:Pyridoxine:Information storage and processing:Cellular processes and signaling:Metabolism:Poorly characterized" 267 "Energy production and conversion:Superfamily I DNA and RNA helicases:4-hydroxybenzoate polyprenyltransferase and related prenyltransferases:Nitroreductase:Gamma-aminobutyrate permease and related permeases:ABC-type multidrug transport system, ATPase and permease components:Type II secretory pathway, pullulanase PulA and related glycosidases:ABC-type sugar transport system, periplasmic component:Predicted double-stranded RNA/RNA-DNA hybrid binding protein:Putative peptidoglycan-binding domain-containing protein:Uncharacterized protein conserved in bacteria:Transposase and inactivated derivatives:Predicted membrane protein:Site-specific recombinase XerD:Predicted secreted protein:Amino acid transport and metabolism:Carbohydrate transport and metabolism:Coenzyme transport and metabolism:Replication, recombination and repair:Cell wall/membrane/envelope biogenesis:General function prediction only:Function unknown:pulA_typeI:Defense mechanisms:Poorly characterized:Metabolism:Cellular processes and signaling:Information storage and processing" 268 "Energy production and conversion:Flavodoxins:Uncharacterized membrane protein:Transcriptional regulators:FOG: FHA domain:Uncharacterized conserved protein:Predicted exonuclease:Transcription:Replication, recombination and repair:Function unknown:Signal transduction mechanisms:spo_II_M:TIGR04086_membr:Metabolism:Cellular processes and signaling:Information storage and processing:Sporulation and germination:Cellular processes:Poorly characterized" 269 "Glycogen synthase:ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component:ADP-glucose pyrophosphorylase:NADPH-dependent glutamate synthase beta chain and related oxidoreductases:Signal recognition particle GTPase:ABC-type dipeptide/oligopeptide/nickel transport systems, permease components:5'-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases:Protease subunit of ATP-dependent Clp proteases:ABC-type dipeptide/oligopeptide/nickel transport systems, permease components:Chromosome segregation ATPases:Predicted transcriptional regulators:DNA segregation ATPase FtsK/SpoIIIE and related proteins:Zinc metalloprotease (elastase):Predicted ATPase:ABC-type oligopeptide transport system, periplasmic component:Uncharacterized protein conserved in bacteria:ABC-type oligopeptide transport system, ATPase component:Cell cycle control, cell division, chromosome partitioning:Amino acid transport and metabolism:Nucleotide transport and metabolism:Carbohydrate transport and metabolism:Transcription:Posttranslational modification, protein turnover, chaperones:Inorganic ion transport and metabolism:General function prediction only:Function unknown:ftsY:GGDEF:LPXTG_anchor:GOGAT_sm_gam:oligo_HPY:glgD:glgA:SMC_prok_B:spore_CotS:M6dom_TIGR03296:Intracellular trafficking, secretion, and vesicular transport:Information storage and processing:Other:Cell envelope:Other:Signal transduction:Sporulation and germination:Cellular processes:Amino acids, peptides and amines:Transport and binding proteins:Protein and peptide secretion and trafficking:Protein fate:Chromosome-associated proteins:DNA metabolism:Biosynthesis and degradation of polysaccharides:Energy metabolism:Cellular processes and signaling:Metabolism:Poorly characterized" 270 "Cytidine deaminase:ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component:Topoisomerase IA:Pseudouridylate synthases, 23S RNA-specific:Predicted endonuclease distantly related to archaeal Holliday junction resolvase:ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component:Predicted nucleotidyltransferase:Phosphomannose isomerase:Site-specific recombinases, DNA invertase Pin homologs:H+/gluconate symporter and related permeases:ABC-type oligopeptide transport system, ATPase component:Uncharacterized conserved protein:Amino acid transport and metabolism:Nucleotide transport and metabolism:Carbohydrate transport and metabolism:Translation, ribosomal structure and biogenesis:Replication, recombination and repair:Inorganic ion transport and metabolism:General function prediction only:Function unknown:rluA_subfam:TIGR00252:topB:oligo_HPY:Conserved:Hypothetical proteins:Amino acids, peptides and amines:Transport and binding proteins:tRNA and rRNA base modification:Protein synthesis:DNA replication, recombination, and repair:DNA metabolism:Metabolism:Poorly characterized:Information storage and processing" 271 "4-aminobutyrate aminotransferase and related aminotransferases:Co-chaperonin GroES (HSP10):Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain:Nucleotidyltransferase/DNA polymerase involved in DNA repair:Molecular chaperone:Chaperonin GroEL (HSP60 family):dsRNA-specific ribonuclease:ABC-type antimicrobial peptide transport system, permease component:Serine/threonine protein phosphatase:Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain:Predicted ATP-dependent serine protease:UDP-glucose 4-epimerase:ABC-type antimicrobial peptide transport system, ATPase component:Transcriptional regulator:Uncharacterized homolog of PSP1:Arginine degradation protein (predicted deacylase):Predicted multitransmembrane protein:Amino acid transport and metabolism:Transcription:Replication, recombination and repair:Cell wall/membrane/envelope biogenesis:Posttranslational modification, protein turnover, chaperones:Function unknown:Signal transduction mechanisms:sms:galE:RNaseIII:GroEL:Defense mechanisms:Information storage and processing:Protein folding and stabilization:Protein fate:RNA processing:Poorly characterized:DNA replication, recombination, and repair:DNA metabolism:Sugars:Energy metabolism:Transcription:Metabolism:Cellular processes and signaling" 272 "Energy production and conversion:N-formylmethionyl-tRNA deformylase:Selenocysteine lyase:Glycerol kinase:Nitroreductase:Recombinational DNA repair ATPase (RecF pathway):Uncharacterized membrane protein:Predicted metal-dependent hydrolase:DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog:Predicted flavoproteins:Uncharacterized proteins involved in stress response, homologs of TerZ and putative cAMP-binding protein CABP1:Predicted transcriptional regulator containing CBS domains:Capsular polysaccharide biosynthesis protein:Amino acid transport and metabolism:Carbohydrate transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:Replication, recombination and repair:Cell wall/membrane/envelope biogenesis:General function prediction only:Function unknown:Signal transduction mechanisms:pept_deformyl:TIGR00275:recf:glycerol_kin:rpoN_sigma:DNA replication, recombination, and repair:DNA metabolism:Other:Energy metabolism:Protein modification and repair:Poorly characterized:Cellular processes and signaling:Information storage and processing:Enzymes of unknown specificity:Unknown function:Metabolism:Protein fate:Transcription factors:Transcription" 273 "Energy production and conversion:tRNA delta(2)-isopentenylpyrophosphate transferase:Uncharacterized conserved protein:Glycosyltransferases involved in cell wall biogenesis:ATP-dependent Zn proteases:Uridine kinase:Putative intracellular protease/amidase:Predicted membrane-associated Zn-dependent proteases 1:Collagenase and related proteases:Fe-S oxidoreductase:Predicted membrane protein, hemolysin III homolog:Uncharacterized protein conserved in bacteria:Uncharacterized protein conserved in bacteria:Small primase-like proteins (Toprim domain):L-serine deaminase:Uncharacterized protein with SCP/PR1 domains:Amino acid transport and metabolism:Nucleotide transport and metabolism:Translation, ribosomal structure and biogenesis:Replication, recombination and repair:Cell wall/membrane/envelope biogenesis:Posttranslational modification, protein turnover, chaperones:General function prediction only:Function unknown:miaA:5S_RNA_mat_M5:sda_beta:hlyIII:FtsH_fam:spore_IV_B:spore_YkwD:Transcription:Glycolysis/gluconeogenesis:Energy metabolism:Protein fate:Metabolism:Cellular processes and signaling:Information storage and processing:Sporulation and germination:Cellular processes:Degradation of proteins, peptides, and glycopeptides:Poorly characterized:tRNA and rRNA base modification:Protein synthesis:RNA processing" 274 "Energy production and conversion:Dephospho-CoA kinase:ABC-type sugar transport system, permease component:Aspartokinases:6-pyruvoyl-tetrahydropterin synthase:Membrane-fusion protein:ABC-type sugar transport systems, permease components:ABC-type sugar transport system, periplasmic component:Glycosyl transferases, related to UDP-glucuronosyltransferase:Uncharacterized conserved protein:Amino acid transport and metabolism:Carbohydrate transport and metabolism:Coenzyme transport and metabolism:Cell wall/membrane/envelope biogenesis:Function unknown:TIGR00152:asp_kinases:MGT:spore_YlmC_YmxH:6_pyr_pter_rel:Poorly characterized:Sporulation and germination:Toxin production and resistance:Cellular processes:Amino acid biosynthesis:Metabolism:Cellular processes and signaling:Pantothenate and coenzyme A:Biosynthesis of cofactors, prosthetic groups, and carriers:Aspartate family" 275 "Guanylate kinase:dUTPase:DNA-directed RNA polymerase specialized sigma subunit:Uncharacterized protein conserved in bacteria:Nucleotide transport and metabolism:Transcription:Function unknown:dut:sigma70-ECF:2'-Deoxyribonucleotide metabolism:Purines, pyrimidines, nucleosides, and nucleotides:Information storage and processing:Metabolism:Poorly characterized" 276 "Sulfite reductase, beta subunit (hemoprotein):Predicted amidohydrolase:Adenine/guanine phosphoribosyltransferases and related PRPP-binding proteins:Predicted hydrolase of the metallo-beta-lactamase superfamily:Uncharacterized membrane protein (homolog of Drosophila rhomboid):Amino acid transporters:Predicted acetyltransferases and hydrolases with the alpha/beta hydrolase fold:ABC-type multidrug transport system, ATPase component:Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily:Transcriptional regulators:Homocysteine/selenocysteine methylase (S-methylmethionine-dependent):Dioxygenases related to 2-nitropropane dioxygenase:Transcriptional regulators:Predicted flavin-nucleotide-binding protein:Uncharacterized protein conserved in bacteria:Amino acid transport and metabolism:Nucleotide transport and metabolism:Transcription:Cell wall/membrane/envelope biogenesis:Inorganic ion transport and metabolism:General function prediction only:Function unknown:nadE:MG423:apt:Defense mechanisms:Cellular processes and signaling:Information storage and processing:Pyridine nucleotides:Biosynthesis of cofactors, prosthetic groups, and carriers:Poorly characterized:Hypothetical proteins:Salvage of nucleosides and nucleotides:Purines, pyrimidines, nucleosides, and nucleotides:Conserved:Metabolism" 277 "Energy production and conversion:Uncharacterized conserved protein:Predicted Co/Zn/Cd cation transporters:Nicotinate-nucleotide pyrophosphorylase:Dihydrodipicolinate synthase/N-acetylneuraminate lyase:UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N-acetylglucosamine-1-phosphate transferase:NTP pyrophosphohydrolases including oxidative damage repair enzymes:Transcriptional regulator:Predicted phosphatase/phosphohexomutase:ABC-type metal ion transport system, periplasmic component/surface adhesin:NifU homolog involved in Fe-S cluster formation:Serine acetyltransferase:Predicted HD superfamily hydrolase involved in NAD metabolism:Type II secretory pathway, prepilin signal peptidase PulO and related peptidases:Predicted membrane protein:Cystathionine beta-lyase family protein involved in aluminum resistance:Signal transduction histidine kinase:Amino acid transport and metabolism:Coenzyme transport and metabolism:Transcription:Replication, recombination and repair:Cell wall/membrane/envelope biogenesis:Cell motility:Posttranslational modification, protein turnover, chaperones:Inorganic ion transport and metabolism:General function prediction only:Function unknown:Signal transduction mechanisms:nadC:TIGR00106:sensory_box:mraY:TIGR00488:dapA:cysE:CDF:HAD-SF-IA-v3:SUF_scaf_2:Intracellular trafficking, secretion, and vesicular transport:Pyridine nucleotides:Other:General:Enzymes of unknown specificity:Unknown function:Cations and iron carrying compounds:Transport and binding proteins:Small molecule interactions:Regulatory functions:Poorly characterized:Biosynthesis of cofactors, prosthetic groups, and carriers:Metabolism:Cellular processes and signaling:Information storage and processing:Biosynthesis and degradation of murein sacculus and peptidoglycan:Serine family:Aspartate family:Amino acid biosynthesis:Cell envelope" 278 "Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), A subunit:ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component:ATP-dependent exoDNAse (exonuclease V), alpha subunit - helicase superfamily I member:ABC-type amino acid transport/signal transduction systems, periplasmic component/domain:ABC-type dipeptide/oligopeptide/nickel transport systems, permease components:DNA-directed RNA polymerase specialized sigma subunit:Predicted glycosyltransferases:Preprotein translocase subunit SecG:Histidinol phosphatase and related hydrolases of the PHP family:Transcriptional regulators:Thiamine pyrophosphokinase:Uncharacterized ABC-type transport system, periplasmic component/surface lipoprotein:Transcriptional regulators:ABC-type sugar transport system, periplasmic component:Anti-sigma regulatory factor (Ser/Thr protein kinase):Uncharacterized protein conserved in bacteria:Uncharacterized conserved protein:Predicted HD-superfamily hydrolase:Amino acid transport and metabolism:Carbohydrate transport and metabolism:Coenzyme transport and metabolism:Transcription:Replication, recombination and repair:Inorganic ion transport and metabolism:General function prediction only:Function unknown:Signal transduction mechanisms:secG:gyrA:thi_PPkinase:recD_rel:HEQRo_perm_3TM:oligo_HPY:hisJ_fam:spIIAB:spore_sigF:YaaA_near_RecF:Intracellular trafficking, secretion, and vesicular transport:DNA replication, recombination, and repair:DNA metabolism:Amino acids, peptides and amines:Poorly characterized:Cellular processes and signaling:Information storage and processing:Thiamine:Biosynthesis of cofactors, prosthetic groups, and carriers:Enzymes of unknown specificity:Unknown function:Sporulation and germination:Cellular processes:Metabolism:Transport and binding proteins:Protein and peptide secretion and trafficking:Protein fate" 279 "Energy production and conversion:Predicted ATPase of the PP-loop superfamily implicated in cell cycle control:Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase:Selenocysteine lyase:Predicted hydrolases of the HAD superfamily:Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, alpha subunit:Lactate dehydrogenase and related dehydrogenases:Acyl carrier protein phosphodiesterase:Uncharacterized low-complexity proteins:Uncharacterized protein conserved in bacteria:Type II secretory pathway, pullulanase PulA and related glycosidases:Predicted aminopeptidases:Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog):Uncharacterized conserved protein:Uncharacterized conserved protein:Predicted integral membrane protein:Cell cycle control, cell division, chromosome partitioning:Amino acid transport and metabolism:Carbohydrate transport and metabolism:Coenzyme transport and metabolism:Lipid transport and metabolism:General function prediction only:Function unknown:Signal transduction mechanisms:Cof-subfamily:hisC:LPXTG_anchor:am_tr_V_EF2568:pulA_typeI:lysidine_TilS_N:spore_III_AE:spo_ytxC:OAFO_sf:Unknown function:Sporulation and germination:Cellular processes:tRNA and rRNA base modification:Protein synthesis:Metabolism:Poorly characterized:Cellular processes and signaling:Other:Cell envelope:Histidine family:Amino acid biosynthesis:Enzymes of unknown specificity" 280 "Aspartate oxidase:Dethiobiotin synthetase:Nicotinate-nucleotide pyrophosphorylase:Adenosylmethionine-8-amino-7-oxononanoate aminotransferase:Quinolinate synthase:Biotin synthase and related enzymes:Uncharacterized conserved protein:Cu/Zn superoxide dismutase:Uncharacterized conserved protein:Phage-related holin (Lysis protein):Bacterial surface proteins containing Ig-like domains:Coenzyme transport and metabolism:Cell motility:Inorganic ion transport and metabolism:General function prediction only:Function unknown:nadC:bioD:bioB:bioA:nadA:holin_tox_secr:Biotin:Poorly characterized:Cellular processes and signaling:Pyridine nucleotides:Metabolism:Biosynthesis of cofactors, prosthetic groups, and carriers:Prophage functions:Mobile and extrachromosomal element functions" 281 "Xanthosine triphosphate pyrophosphatase:Ribonuclease HII:1-acyl-sn-glycerol-3-phosphate acyltransferase:Translation elongation factor P (EF-P)/translation initiation factor 5A (eIF-5A):Ribosomal protein S20:Recombinational DNA repair protein (RecF pathway):Nucleotide-binding protein implicated in inhibition of septum formation:ATPase components of ABC transporters with duplicated ATPase domains:Topoisomerase IA:Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family:Uncharacterized protein conserved in bacteria:Asp-tRNAAsn/Glu-tRNAGln amidotransferase C subunit:Bacterial cell division membrane protein:Predicted Zn-dependent peptidases, insulinase-like:Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog):DNA-directed RNA polymerase, subunit K/omega:Regulators of stationary/sporulation gene expression:AT-rich DNA-binding protein:Cell cycle control, cell division, chromosome partitioning:Nucleotide transport and metabolism:Lipid transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:Replication, recombination and repair:Posttranslational modification, protein turnover, chaperones:General function prediction only:Function unknown:S20:efp:TIGR00042:DNA_YbaB_EbfC:gatC:maf:AGP_acyltrn:recR:rpoZ:rpmH_bact:topA_bact:lp_hng_hel_AbrB:rodA_shape:Unknown function:Cell division:Cellular processes:Translation factors:Ribosomal proteins: synthesis and modification:tRNA aminoacylation:Protein synthesis:Poorly characterized:Transcription:DNA replication, recombination, and repair:DNA metabolism:DNA interactions:Regulatory functions:Biosynthesis:Fatty acid and phospholipid metabolism:DNA-dependent RNA polymerase:Metabolism:Cellular processes and signaling:Information storage and processing:General" 282 "Undecaprenyl pyrophosphate synthase:Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase:Nuclease subunit of the excinuclease complex:Molybdopterin biosynthesis enzymes:Predicted hydrolases of the HAD superfamily:CDP-diglyceride synthetase:ABC-type Fe3+-siderophore transport system, permease component:Predicted permeases:ABC-type metal ion transport system, periplasmic component/surface adhesin:Nicotinic acid mononucleotide adenylyltransferase:ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components:Phosphatidylserine synthase:Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific:Type II secretory pathway, component PulF:Predicted phosphohydrolase:Transcriptional regulators:Uncharacterized protein conserved in bacteria:Uncharacterized protein containing a Zn-finger-like domain:Uncharacterized conserved protein:Uncharacterized conserved protein:Amino acid transport and metabolism:Carbohydrate transport and metabolism:Coenzyme transport and metabolism:Lipid transport and metabolism:Transcription:Replication, recombination and repair:Cell motility:Inorganic ion transport and metabolism:General function prediction only:Function unknown:uppS:Cof-subfamily:molyb_syn:uvrC:pssA:TIGR00482:PTBA:IV_pilin_GFxxxE:Intracellular trafficking, secretion, and vesicular transport:Signal transduction:Pyridine nucleotides:Biosynthesis of cofactors, prosthetic groups, and carriers:Enzymes of unknown specificity:Unknown function:Protein and peptide secretion and trafficking:Protein fate:DNA replication, recombination, and repair:DNA metabolism:Biosynthesis:Fatty acid and phospholipid metabolism:PTS:Cell envelope:Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides:Information storage and processing:Cellular processes and signaling:Metabolism:Poorly characterized" 283 "Chromatin structure and dynamics:Energy production and conversion:Cytosine deaminase and related metal-dependent hydrolases:UDP-galactopyranose mutase:Transcriptional regulator:DNA polymerase sliding clamp subunit (PCNA homolog):Hypoxanthine-guanine phosphoribosyltransferase:Predicted dehydrogenases and related proteins:UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase:UDP-N-acetylmuramyl tripeptide synthase:NAD-dependent aldehyde dehydrogenases:Predicted GTPases:Transcription-repair coupling factor (superfamily II helicase):Histone acetyltransferase:Amidases related to nicotinamidase:Predicted membrane-associated HD superfamily hydrolase:Uncharacterized conserved protein:Uncharacterized conserved protein:Uncharacterized proteins, homologs of microcin C7 resistance protein MccF:DnaK suppressor protein:Transcriptional regulators:Transcriptional regulator/sugar kinase:Uncharacterized protein conserved in bacteria:Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain:Uncharacterized protein conserved in bacteria:Predicted membrane protein:Integral membrane protein (PIN domain superfamily):Nucleotide transport and metabolism:Carbohydrate transport and metabolism:Transcription:Replication, recombination and repair:Cell wall/membrane/envelope biogenesis:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:Function unknown:Signal transduction mechanisms:UDP-GALP_mutase:small_GTP:HDIG:mfd:dnan:murE:murG:HGPRTase:spore_yteA:Defense mechanisms:Purines, pyrimidines, nucleosides, and nucleotides:Salvage of nucleosides and nucleotides:DNA metabolism:DNA replication, recombination, and repair:Cellular processes:Sporulation and germination:Unknown function:General:Cell envelope:Biosynthesis and degradation of murein sacculus and peptidoglycan:Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides:Poorly characterized:Metabolism:Information storage and processing:Cellular processes and signaling" 284 "Fructose/tagatose bisphosphate aldolase:Sugar kinases, ribokinase family:Ribose 5-phosphate isomerase RpiB:Sugar (pentulose and hexulose) kinases:Fructose-1-phosphate kinase and related fructose-6-phosphate kinase (PfkB):Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific:Phosphotransferase system cellobiose-specific component IIA:Alpha-galactosidases/6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases:L-arabinose isomerase:Beta-glucosidase/6-phospho-beta-glucosidase/beta-galactosidase:Arabinose efflux permease:Predicted HD-superfamily hydrolase:Phosphoketolase:Carbohydrate transport and metabolism:General function prediction only:cbbA:rpiB_lacA_lacB:EIIB_glc:SP:lacG:phage_rep_org_N:1-PFK:Carbohydrates, organic alcohols, and acids:Transport and binding proteins:Metabolism:Glycolysis/gluconeogenesis:Energy metabolism:Biosynthesis and degradation of polysaccharides:Poorly characterized:PTS:Signal transduction:Prophage functions:Mobile and extrachromosomal element functions" 285 "Predicted hydrolases of the HAD superfamily:tRNA nucleotidyltransferase/poly(A) polymerase:FOG: CheY-like receiver:Chemotaxis signal transduction protein:Methyl-accepting chemotaxis protein:Transcriptional regulator:Phosphotransferase system cellobiose-specific component IIB:Phosphotransferase system cellobiose-specific component IIC:Acetyltransferases, including N-acetylases of ribosomal proteins:Flagellar hook protein FlgE:Arginine/lysine/ornithine decarboxylases:Uncharacterized conserved protein related to pyruvate formate-lyase activating enzyme:Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain:Beta-glucosidase/6-phospho-beta-glucosidase/beta-galactosidase:Uncharacterized conserved protein:Bacterial surface proteins containing Ig-like domains:Amino acid transport and metabolism:Carbohydrate transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:Cell motility:General function prediction only:Function unknown:Signal transduction mechanisms:lacE:BGL:FlgEFG_subfam:Cellular processes and signaling:Information storage and processing:Metabolism:Signal transduction:Poorly characterized:PTS" 286 "Xaa-Pro aminopeptidase:Dihydroorotase and related cyclic amidohydrolases:Glycine/serine hydroxymethyltransferase:Glucose-6-phosphate isomerase:1-acyl-sn-glycerol-3-phosphate acyltransferase:DNA primase (bacterial type):ATP-dependent exoDNAse (exonuclease V), alpha subunit - helicase superfamily I member:Amino acid transporters:Phosphoserine phosphatase:UDP-galactopyranose mutase:Esterase/lipase:UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase:Cell division protein FtsI/penicillin-binding protein 2:Nucleoside phosphorylase:7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase:Mannose-1-phosphate guanylyltransferase:Predicted HD superfamily hydrolase:Transcriptional regulators:Di- and tripeptidases:Amino acid transport and metabolism:Nucleotide transport and metabolism:Carbohydrate transport and metabolism:Coenzyme transport and metabolism:Lipid transport and metabolism:Transcription:Replication, recombination and repair:Cell wall/membrane/envelope biogenesis:General function prediction only:UDP-GALP_mutase:folB:pyrC_multi:murG:dnaG:recD_rel:HAD-SF-IB:MTA/SAH-Nsdase:peptidase-T:Protein fate:DNA replication, recombination, and repair:DNA metabolism:Salvage of nucleosides and nucleotides:Pyrimidine ribonucleotide biosynthesis:Purines, pyrimidines, nucleosides, and nucleotides:Degradation of proteins, peptides, and glycopeptides:Poorly characterized:Cellular processes and signaling:Information storage and processing:Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides:Biosynthesis and degradation of murein sacculus and peptidoglycan:Cell envelope:Folic acid:Biosynthesis of cofactors, prosthetic groups, and carriers:Enzymes of unknown specificity:Unknown function:Metabolism" 287 "Zn-dependent hydrolases, including glyoxylases:Predicted phosphatases:Superfamily II DNA/RNA helicases, SNF2 family:Transcriptional regulator:Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily):Methionine synthase I (cobalamin-dependent), methyltransferase domain:Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain:Predicted transcriptional regulators:ABC-type multidrug transport system, permease component:Metal-dependent hydrolases of the beta-lactamase superfamily III:Aspartyl aminopeptidase:Predicted signal transduction protein with a C-terminal ATPase domain:Type IV secretory pathway, VirD4 components:Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains:Putative primosome component and related proteins:Amino acid transport and metabolism:Transcription:Replication, recombination and repair:General function prediction only:Signal transduction mechanisms:sensory_box:DnaD_dom:Intracellular trafficking, secretion, and vesicular transport:Defense mechanisms:Metabolism:Cellular processes and signaling:Information storage and processing:Prophage functions:Mobile and extrachromosomal element functions:Small molecule interactions:Regulatory functions:Poorly characterized" 288 "Energy production and conversion:Dihydroxyacid dehydratase/phosphogluconate dehydratase:Fructose/tagatose bisphosphate aldolase:Multimeric flavodoxin WrbA:Ribose 5-phosphate isomerase RpiB:Flavodoxins:Fructose-1-phosphate kinase and related fructose-6-phosphate kinase (PfkB):Predicted glycosyltransferases:Cobalamin biosynthesis protein CobD/CbiB:Transcriptional regulators of sugar metabolism:Phosphotransferase system cellobiose-specific component IIA:Phosphotransferase system cellobiose-specific component IIC:Glycerate kinase:Lysophospholipase:H+/gluconate symporter and related permeases:Beta-glucosidase/6-phospho-beta-glucosidase/beta-galactosidase:Amino acid transport and metabolism:Carbohydrate transport and metabolism:Coenzyme transport and metabolism:Lipid transport and metabolism:Transcription:General function prediction only:TIGR00045:cbbA:cobD:lac_pts_IIC:rpiB_lacA_lacB:gntP:lacG:1-PFK:Carbohydrates, organic alcohols, and acids:Transport and binding proteins:Other:Biosynthesis and degradation of polysaccharides:Glycolysis/gluconeogenesis:Energy metabolism:Information storage and processing:Poorly characterized:PTS:Signal transduction:Metabolism:Heme, porphyrin, and cobalamin:Biosynthesis of cofactors, prosthetic groups, and carriers" 289 "Energy production and conversion:Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase:Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases:Aldo/keto reductases, related to diketogulonate reductase:Flavodoxins:Fe2+/Zn2+ uptake regulation proteins:Protease subunit of ATP-dependent Clp proteases:FOG: CheY-like receiver:Predicted endonuclease involved in recombination (possible Holliday junction resolvase in Mycoplasmas and B. subtilis):Predicted hydrolase (HAD superfamily):UDP-glucose 4-epimerase:UDP-glucose pyrophosphorylase:Transcriptional regulators:Uncharacterized protein, involved in the regulation of septum location:Uncharacterized protein conserved in bacteria:Uncharacterized protein conserved in bacteria:Amino acid transport and metabolism:Nucleotide transport and metabolism:Carbohydrate transport and metabolism:Coenzyme transport and metabolism:Transcription:Replication, recombination and repair:Cell wall/membrane/envelope biogenesis:Posttranslational modification, protein turnover, chaperones:Inorganic ion transport and metabolism:General function prediction only:Function unknown:Signal transduction mechanisms:RNAse_H_YqgF:clpP:galU:ilvE_II:HAD-SF-IA-v3:flav_short:spore_0_A:Intracellular trafficking, secretion, and vesicular transport:Pyruvate family:Amino acid biosynthesis:General:Enzymes of unknown specificity:Unknown function:Sporulation and germination:Cellular processes:Degradation of proteins, peptides, and glycopeptides:Protein fate:Electron transport:Energy metabolism:Cell envelope:Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides:Information storage and processing:Cellular processes and signaling:Metabolism:Poorly characterized" 290 "Glutamate synthase domain 2:Hydrogenase maturation factor:Hydrogenase maturation factor:Glutamate dehydrogenase/leucine dehydrogenase:Molybdopterin biosynthesis enzymes:Mn-dependent transcriptional regulator:Sporulation protein and related proteins:Uncharacterized membrane protein, required for spore maturation in B.subtilis.:Cell wall hydrolyses involved in spore germination:Uncharacterized conserved protein:Cell cycle control, cell division, chromosome partitioning:Amino acid transport and metabolism:Coenzyme transport and metabolism:Transcription:Cell wall/membrane/envelope biogenesis:Posttranslational modification, protein turnover, chaperones:General function prediction only:Function unknown:hypC_hupF:molyb_syn:hypE:SpoIID_LytB:spore_IV_A:spore_ytfJ:Unknown function:Sporulation and germination:Cellular processes:Protein modification and repair:Protein fate:Poorly characterized:General:Metabolism:Cellular processes and signaling:Information storage and processing" 291 "Energy production and conversion:Riboflavin synthase beta-chain:3,4-dihydroxy-2-butanone 4-phosphate synthase:Riboflavin synthase alpha chain:Predicted glutamine amidotransferase involved in pyridoxine biosynthesis:Multimeric flavodoxin WrbA:Putative intracellular protease/amidase:Rad3-related DNA helicases:Metal-dependent hydrolases of the beta-lactamase superfamily II:Predicted P-loop-containing kinase:Predicted transcriptional regulators:Uncharacterized protein conserved in bacteria:Pyrimidine reductase, riboflavin biosynthesis:Dioxygenases related to 2-nitropropane dioxygenase:Electron transfer flavoprotein, beta subunit:ATPase related to the helicase subunit of the Holliday junction resolvase:Predicted HD-superfamily hydrolase:Type IV secretory pathway, VirD4 components:Uncharacterized protein conserved in bacteria:NAD+--asparagine ADP-ribosyltransferase:Coenzyme transport and metabolism:Transcription:Replication, recombination and repair:General function prediction only:Function unknown:Signal transduction mechanisms:lumazine-synth:ribE:ribD_Cterm:HDIG:ribA:enACPred_II:PLP_synth_Pdx2:para_beta_helix:Intracellular trafficking, secretion, and vesicular transport:Biosynthesis of cofactors, prosthetic groups, and carriers:Pyridoxine:Riboflavin, FMN, and FAD:Information storage and processing:Cellular processes and signaling:Metabolism:Poorly characterized" 292 "Aspartyl/asparaginyl-tRNA synthetases:Transketolase:Prephenate dehydratase:Triosephosphate isomerase:Preprotein translocase subunit SecY:Translation initiation factor 1 (IF-1):ATP-dependent Zn proteases:Zn-dependent hydrolases, including glyoxylases:Adenine/guanine phosphoribosyltransferases and related PRPP-binding proteins:Phosphoglyceromutase:UDP-N-acetylmuramate-alanine ligase:Thiamine biosynthesis enzyme ThiH and related uncharacterized enzymes:Uncharacterized conserved protein:Uncharacterized conserved protein, contains double-stranded beta-helix domain:Di- and tripeptidases:Uncharacterized FAD-dependent dehydrogenases:Formyltetrahydrofolate synthetase:Predicted membrane protein:Lantibiotic modifying enzyme:Amino acid transport and metabolism:Nucleotide transport and metabolism:Carbohydrate transport and metabolism:Coenzyme transport and metabolism:Translation, ribosomal structure and biogenesis:Cell wall/membrane/envelope biogenesis:Posttranslational modification, protein turnover, chaperones:General function prediction only:Function unknown:infA:tktlase_bact:tim:asnS:3a0501s007:murC:FtsH_fam:pgm_bpd_ind:purR_Bsub:peptidase-T:rSAM_HydG:Intracellular trafficking, secretion, and vesicular transport:Defense mechanisms:Energy metabolism:Translation factors:Information storage and processing:Cellular processes and signaling:Metabolism:Poorly characterized:Cell envelope:Protein modification and repair:Degradation of proteins, peptides, and glycopeptides:Protein and peptide secretion and trafficking:Protein fate:Biosynthesis and degradation of murein sacculus and peptidoglycan:tRNA aminoacylation:Protein synthesis:DNA interactions:Regulatory functions:Pentose phosphate pathway:Glycolysis/gluconeogenesis" 293 "Energy production and conversion:Glycosyltransferase:Predicted Zn-dependent peptidases:Arylsulfatase regulator (Fe-S oxidoreductase):Cell wall-associated hydrolases (invasion-associated proteins):Predicted hydrolase (HAD superfamily):ABC-type multidrug transport system, ATPase and permease components:Glycosyltransferases, probably involved in cell wall biogenesis:Predicted glycosyltransferases:NADH:flavin oxidoreductases, Old Yellow Enzyme family:Cell wall/membrane/envelope biogenesis:General function prediction only:glyc2_xrt_Gpos1:Defense mechanisms:Poorly characterized:Metabolism:Cellular processes and signaling" 294 "Energy production and conversion:ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component:Superfamily II DNA/RNA helicases, SNF2 family:Adenylate kinase and related kinases:ABC-type Fe3+-siderophore transport system, permease component:Signal transduction histidine kinase:Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain:Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, gamma subunit:Enoyl-CoA hydratase/carnithine racemase:Phosphomannomutase:ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components:Acetyltransferases, including N-acetylases of ribosomal proteins:ABC-type metal ion transport system, permease component:Uncharacterized protein conserved in bacteria:Molybdenum cofactor biosynthesis enzyme:Methenyl tetrahydrofolate cyclohydrolase:ABC-type oligopeptide transport system, ATPase component:Amino acid transport and metabolism:Nucleotide transport and metabolism:Carbohydrate transport and metabolism:Coenzyme transport and metabolism:Lipid transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:Replication, recombination and repair:Inorganic ion transport and metabolism:Function unknown:Signal transduction mechanisms:oligo_HPY:moaA:IOR_beta:Cellular processes and signaling:Information storage and processing:Molybdopterin:Biosynthesis of cofactors, prosthetic groups, and carriers:Amino acids, peptides and amines:Transport and binding proteins:Metabolism:Poorly characterized" 295 "Energy production and conversion:Fructose/tagatose bisphosphate aldolase:Ribosomal protein L28:Uncharacterized flavoproteins:Predicted phosphatase/phosphohexomutase:Signal peptidase I:Fe2+/Zn2+ uptake regulation proteins:Bacterial nucleoid DNA-binding protein:Predicted RNA binding protein (contains ribosomal protein S1 domain):4-diphosphocytidyl-2-methyl-D-erithritol synthase:Uncharacterized protein conserved in bacteria:Uncharacterized host factor I protein:Phosphotransferase system, HPr-related proteins:Uncharacterized conserved protein:FOG: EAL domain:Cell division initiation protein:Predicted membrane protein:Integral membrane protein (PIN domain superfamily):Cell cycle control, cell division, chromosome partitioning:Carbohydrate transport and metabolism:Lipid transport and metabolism:Translation, ribosomal structure and biogenesis:Replication, recombination and repair:Inorganic ion transport and metabolism:General function prediction only:Function unknown:Signal transduction mechanisms:L28:cbbA:ispD:PTS_HPr_family:HAD-SF-IA-v3:sigpep_I_bact:Hfq:DivI1A_domain:TIGR03905_4_Cys:Intracellular trafficking, secretion, and vesicular transport:Other:Regulatory functions:Glycolysis/gluconeogenesis:Energy metabolism:Unknown function:PTS:Information storage and processing:Cellular processes and signaling:Metabolism:Poorly characterized:Other:Biosynthesis of cofactors, prosthetic groups, and carriers:General:Enzymes of unknown specificity:Signal transduction:Protein and peptide secretion and trafficking:Protein fate:Ribosomal proteins: synthesis and modification:Protein synthesis" 296 "Energy production and conversion:Arginyl-tRNA synthetase:Homoserine kinase:Tryptophanyl-tRNA synthetase:Uncharacterized conserved protein:Folylpolyglutamate synthase:ABC-type transport system involved in Fe-S cluster assembly, ATPase component:Selenocysteine lyase:Valyl-tRNA synthetase:Transcriptional regulator:Ferredoxin:D-alanyl-D-alanine carboxypeptidase:Predicted flavin-nucleotide-binding protein:Bacterial surface proteins containing Ig-like domains:Predicted integral membrane protein:Amino acid transport and metabolism:Coenzyme transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:Cell wall/membrane/envelope biogenesis:Cell motility:Posttranslational modification, protein turnover, chaperones:General function prediction only:Function unknown:thrB:trpS:valS:argS:TIGR01033:folC:sufC:sufS:Aspartate family:Poorly characterized:Cellular processes and signaling:Information storage and processing:Folic acid:Other:Biosynthesis of cofactors, prosthetic groups, and carriers:Metabolism:Amino acid biosynthesis:tRNA aminoacylation:Protein synthesis:DNA interactions:Regulatory functions" 297 "Energy production and conversion:Ammonia permease:Adenylosuccinate lyase:Folylpolyglutamate synthase:Dihydropteroate synthase and related enzymes:tRNA-(guanine-N1)-methyltransferase:Valyl-tRNA synthetase:Na+-driven multidrug efflux pump:ABC-type dipeptide/oligopeptide/nickel transport systems, permease components:7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase:RimM protein, required for 16S rRNA processing:ABC-type dipeptide/oligopeptide/nickel transport systems, permease components:Predicted HD superfamily hydrolase:Periplasmic glycine betaine/choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein):Na+/H+ antiporter:Predicted ATPase (AAA+ superfamily):Uncharacterized conserved protein:Uncharacterized conserved protein:Response regulator containing CheY-like receiver and SARP domains:Amino acid transport and metabolism:Nucleotide transport and metabolism:Coenzyme transport and metabolism:Translation, ribosomal structure and biogenesis:Cell wall/membrane/envelope biogenesis:Inorganic ion transport and metabolism:General function prediction only:Function unknown:Signal transduction mechanisms:trmD:valS:folB:matE:amt:purB:DHPS:folC:16S_RimM:Defense mechanisms:Transport and binding proteins:tRNA and rRNA base modification:tRNA aminoacylation:Protein synthesis:Poorly characterized:Transcription:Purine ribonucleotide biosynthesis:Purines, pyrimidines, nucleosides, and nucleotides:RNA processing:Metabolism:Cellular processes and signaling:Information storage and processing:Folic acid:Biosynthesis of cofactors, prosthetic groups, and carriers:Other:Cations and iron carrying compounds" 298 "Energy production and conversion:ATPase components of ABC transporters with duplicated ATPase domains:ATPases with chaperone activity, ATP-binding subunit:Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains):Methyl-accepting chemotaxis protein:Fe-S oxidoreductase:Glycosyltransferases, probably involved in cell wall biogenesis:Uncharacterized protein conserved in bacteria:Acetyltransferases, including N-acetylases of ribosomal proteins:Predicted phosphohydrolase:Methylglyoxal synthase:Ketopantoate reductase:HD-GYP domain:Uncharacterized homolog of the cytoplasmic domain of flagellar protein FhlB:Uncharacterized proteins involved in stress response, homologs of TerZ and putative cAMP-binding protein CABP1:Predicted signaling protein consisting of a modified GGDEF domain and a DHH domain:Uncharacterized conserved protein:Uncharacterized protein conserved in bacteria:Predicted membrane protein:Uncharacterized protein conserved in bacteria with an aminopeptidase-like domain:Uncharacterized protein conserved in bacteria:Carbohydrate transport and metabolism:Coenzyme transport and metabolism:Translation, ribosomal structure and biogenesis:Cell wall/membrane/envelope biogenesis:Cell motility:Posttranslational modification, protein turnover, chaperones:General function prediction only:Function unknown:Signal transduction mechanisms:MGSA:apbA_panE:DegV:Cellular processes and signaling:Information storage and processing:Pantothenate and coenzyme A:Biosynthesis of cofactors, prosthetic groups, and carriers:General:Unknown function:Other:Energy metabolism:Metabolism:Poorly characterized" 299 "Flagellar biosynthesis/type III secretory pathway ATPase:Flagellar biosynthesis/type III secretory pathway protein:Flagellar motor switch protein:Flagellar basal body rod protein:Flagellar basal body-associated protein:Flagellar hook-basal body protein:Flagellar biosynthesis/type III secretory pathway lipoprotein:Flagellar basal body protein:Flagellar biosynthesis pathway, component FliQ:HD-GYP domain:Uncharacterized protein conserved in bacteria:Flagellar biosynthesis chaperone:ACT domain-containing protein:Predicted enzyme involved in methoxymalonyl-ACP biosynthesis:Signal transduction histidine kinase regulating C4-dicarboxylate transport system:Cell motility:Posttranslational modification, protein turnover, chaperones:Secondary metabolites biosynthesis, transport and catabolism:Function unknown:Signal transduction mechanisms:fliE:fliF:fliG:fliI_yscN:FlgC:FlgB:fliQ:HAD-SF-IIIC:flagell_FliJ:Intracellular trafficking, secretion, and vesicular transport:Energy metabolism:ATP-proton motive force interconversion:Cellular processes:Chemotaxis and motility:Cellular processes and signaling:Metabolism:Poorly characterized" 300 "Hydrogenase maturation factor:Glycosyltransferase:FOG: CBS domain:Predicted Fe-S oxidoreductases:Signal transduction histidine kinase:Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases):Highly conserved protein containing a thioredoxin domain:Predicted membrane protein:Transcriptional regulators:Uncharacterized bacitracin resistance protein:Cytochrome P450:Spore coat protein:Lipid transport and metabolism:Transcription:Cell wall/membrane/envelope biogenesis:Posttranslational modification, protein turnover, chaperones:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:Function unknown:Signal transduction mechanisms:hypF:undec_PP_bacA:spo_yunB:pip_yhgE_Nterm:rSAM_NirJ1:Defense mechanisms:Information storage and processing:Metabolism:Cellular processes and signaling:Poorly characterized:Biosynthesis and degradation of murein sacculus and peptidoglycan:Cell envelope:Sporulation and germination:Cellular processes:Protein modification and repair:Protein fate" 301 "Mannitol-1-phosphate/altronate dehydrogenases:Nuclease subunit of the excinuclease complex:Phosphoenolpyruvate synthase/pyruvate phosphate dikinase:Transcriptional regulator:ABC-type dipeptide/oligopeptide/nickel transport systems, permease components:Amino acid transporters:Co/Zn/Cd efflux system component:Uncharacterized Fe-S protein PflX, homolog of pyruvate formate lyase activating proteins:Acetyltransferases, including N-acetylases of ribosomal proteins:Site-specific recombinases, DNA invertase Pin homologs:Dioxygenases related to 2-nitropropane dioxygenase:Predicted flavoproteins:Na+/melibiose symporter and related transporters:Phosphotransferase system, mannitol-specific IIBC component:DNA gyrase inhibitor:ABC-type sugar transport systems, ATPase components:Uncharacterized protein conserved in bacteria:Uncharacterized membrane protein:Beta-mannanase:Flp pilus assembly protein TadD, contains TPR repeats:Amino acid transport and metabolism:Carbohydrate transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:Replication, recombination and repair:Inorganic ion transport and metabolism:General function prediction only:Function unknown:TIGR00275:gph:mtlA:CDF:GMP_reduct_2:Intracellular trafficking, secretion, and vesicular transport:PTS:Signal transduction:Enzymes of unknown specificity:Unknown function:Cations and iron carrying compounds:Carbohydrates, organic alcohols, and acids:Transport and binding proteins:Nucleotide and nucleoside interconversions:Purines, pyrimidines, nucleosides, and nucleotides:Information storage and processing:Cellular processes and signaling:Metabolism:Poorly characterized" 302 "Alanyl-tRNA synthetase:Uncharacterized conserved protein:Amino acid transporters:Signal recognition particle GTPase:Predicted phosphoesterase:Predicted phosphatase/phosphohexomutase:ABC-type polar amino acid transport system, ATPase component:Lysine efflux permease:Ketopantoate reductase:Transcriptional regulator/sugar kinase:Uncharacterized protein conserved in bacteria:Protein containing tetrapyrrole methyltransferase domain and MazG-like (predicted pyrophosphatase) domain:Amino acid transport and metabolism:Carbohydrate transport and metabolism:Coenzyme transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:General function prediction only:Function unknown:yfcE:alaS:mazG:apbA_panE:ffh:HAD-SF-IA-v3:Intracellular trafficking, secretion, and vesicular transport:Protein fate:tRNA aminoacylation:Protein synthesis:General:Metabolism:Poorly characterized:Information storage and processing:Pantothenate and coenzyme A:Biosynthesis of cofactors, prosthetic groups, and carriers:Cellular processes and signaling:Enzymes of unknown specificity:Unknown function:Protein and peptide secretion and trafficking" 303 "Methionyl-tRNA synthetase:Leucyl-tRNA synthetase:Predicted phosphoesterase:ABC-type amino acid transport system, permease component:Branched-chain amino acid permeases:ABC-type polar amino acid transport system, ATPase component:Amidases related to nicotinamidase:ABC-type metal ion transport system, periplasmic component/surface antigen:Predicted membrane protein:Homoserine trans-succinylase:Regulators of stationary/sporulation gene expression:Threonine aldolase:Xanthine/uracil permeases:Predicted multitransmembrane protein:Amino acid transport and metabolism:Nucleotide transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:Inorganic ion transport and metabolism:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:Function unknown:yfcE:leuS_bact:metG:livcs:ncs2:metA:lp_hng_hel_AbrB:HEQRo_perm_3TM:xxxLxxG_by_4:Aspartate family:Amino acid biosynthesis:Enzymes of unknown specificity:Unknown function:Nucleosides, purines and pyrimidines:Poorly characterized:Transport and binding proteins:tRNA aminoacylation:Protein synthesis:DNA interactions:Regulatory functions:Amino acids, peptides and amines:Metabolism:Information storage and processing" 304 "Energy production and conversion:F0F1-type ATP synthase, beta subunit:Isoleucyl-tRNA synthetase:Ribosomal protein L24:Preprotein translocase subunit SecY:DNA-directed RNA polymerase, alpha subunit/40 kD subunit:Ribosomal protein L31:Ribosomal protein S20:ABC-type Co2+ transport system, permease component:F0F1-type ATP synthase, epsilon subunit (mitochondrial delta subunit):Predicted Fe-S oxidoreductases:FKBP-type peptidyl-prolyl cis-trans isomerase (trigger factor):Predicted permease:F0F1-type ATP synthase, subunit c/Archaeal/vacuolar-type H+-ATPase, subunit K:tmRNA-binding protein:GAF domain-containing protein:Regulators of stationary/sporulation gene expression:GTPases:Regulator of competence-specific genes:Uncharacterized protein conserved in bacteria:Translation, ribosomal structure and biogenesis:Transcription:Posttranslational modification, protein turnover, chaperones:Inorganic ion transport and metabolism:General function prediction only:Function unknown:Signal transduction mechanisms:S20:smpB:L31:tig:ileS:3a0501s007:atpD:rplX_bact:ATP_synt_epsi:ATP_synt_c:lp_hng_hel_AbrB:rpoA:spore_BofA:spore_ylbJ:GTP_HflX:Intracellular trafficking, secretion, and vesicular transport:Cellular processes:Protein and peptide secretion and trafficking:Protein folding and stabilization:Protein fate:Ribosomal proteins: synthesis and modification:tRNA aminoacylation:Poorly characterized:Protein synthesis:DNA-dependent RNA polymerase:Transcription:DNA interactions:Regulatory functions:ATP-proton motive force interconversion:Energy metabolism:Other:Metabolism:Cellular processes and signaling:Information storage and processing:General:Unknown function:Sporulation and germination" 305 "Energy production and conversion:Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase]:3-isopropylmalate dehydratase large subunit:3-isopropylmalate dehydratase small subunit:Serine-pyruvate aminotransferase/archaeal aspartate aminotransferase:Isopropylmalate/homocitrate/citramalate synthases:Dihydroxyacid dehydratase/phosphogluconate dehydratase:Isocitrate/isopropylmalate dehydrogenase:DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog:Predicted membrane protein:Zinc metalloprotease (elastase):Amino acid transport and metabolism:Carbohydrate transport and metabolism:Coenzyme transport and metabolism:Transcription:Function unknown:ilvD:acolac_lg:leuB:LeuA_rel:hacA_fam:leud:sigma70-ECF:Amino acid biosynthesis:Metabolism:Poorly characterized:Pyruvate family:Information storage and processing:General:Unknown function" 306 "Glutamyl- and glutaminyl-tRNA synthetases:Mg-dependent DNase:Acetyltransferase (isoleucine patch superfamily):Tyrosyl-tRNA synthetase:Predicted amidohydrolase:Pseudouridylate synthases, 23S RNA-specific:ABC-type nitrate/sulfonate/bicarbonate transport system, permease component:ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components:Uncharacterized membrane protein, putative virulence factor:Actin-like ATPase involved in cell division:Type II restriction enzyme, methylase subunits:Nicotinic acid mononucleotide adenylyltransferase:ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component:Lysyl-tRNA synthetase (class II):Nicotinic acid phosphoribosyltransferase:Uncharacterized conserved protein:Cell cycle control, cell division, chromosome partitioning:Coenzyme transport and metabolism:Translation, ribosomal structure and biogenesis:Replication, recombination and repair:Inorganic ion transport and metabolism:General function prediction only:rluA_subfam:tyrS:gltX_bact:TIGR00482:lysS_bact:nadE:NAPRTase_put:Defense mechanisms:tRNA and rRNA base modification:tRNA aminoacylation:Protein synthesis:Biosynthesis of cofactors, prosthetic groups, and carriers:Pyridine nucleotides:Information storage and processing:Cellular processes and signaling:Metabolism:Poorly characterized" 307 "Predicted xylanase/chitin deacetylase:Cation/multidrug efflux pump:Phosphatidylserine/phosphatidylglycerophosphate/cardiolipin synthases and related enzymes:Uncharacterized conserved protein:Uncharacterized protein conserved in bacteria:ABC-type transport system, involved in lipoprotein release, permease component:Carbohydrate transport and metabolism:Lipid transport and metabolism:Cell wall/membrane/envelope biogenesis:Function unknown:Defense mechanisms:Cellular processes and signaling:Poorly characterized:Metabolism" 308 "Predicted Fe-S oxidoreductases:Predicted xylanase/chitin deacetylase:Uncharacterized conserved protein:Uncharacterized conserved protein:Putative Ser protein kinase:Carbohydrate transport and metabolism:General function prediction only:Function unknown:Signal transduction mechanisms:spore_ybaN_pdaB:spore_YyaC:spore_yabG:spore_yhbH:spore_CotS:Poorly characterized:Cellular processes:Metabolism:Cellular processes and signaling:Sporulation and germination" 309 "Predicted phosphoesterase:Multimeric flavodoxin WrbA:Predicted permeases:ABC-type transport system involved in multi-copper enzyme maturation, permease component:Transcriptional regulator:Aspartyl aminopeptidase:Predicted transcriptional regulators:Lysophospholipase L1 and related esterases:Uncharacterized conserved protein:Predicted transcriptional regulator:Uncharacterized protein conserved in bacteria:Amino acid transport and metabolism:Transcription:General function prediction only:Function unknown:yfcE:Metabolism:Information storage and processing:Enzymes of unknown specificity:Unknown function:Poorly characterized" 310 "Uracil phosphoribosyltransferase:Pseudouridine synthase:5,10-methylene-tetrahydrofolate dehydrogenase/Methenyl tetrahydrofolate cyclohydrolase:Transcription elongation factor:Predicted S-adenosylmethionine-dependent methyltransferase:Ribosome recycling factor:Translation elongation factor Ts:Uridylate kinase:Uncharacterized protein conserved in bacteria:Ribosome-binding factor A:Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases):D-alanine-D-alanine ligase and related ATP-grasp enzymes:Ribosomal protein HS6-type (S12/L30/L7a):Exonuclease VII small subunit:Zn-dependent proteases:Transcriptional accessory protein:Predicted nucleic-acid-binding protein implicated in transcription termination:Uncharacterized protein conserved in bacteria:Nucleotide transport and metabolism:Coenzyme transport and metabolism:Lipid transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:Replication, recombination and repair:Cell wall/membrane/envelope biogenesis:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:Function unknown:rbfA:TIGR00091:tsf:TruB:frr:upp:D_ala_D_alaTIGR:NusA:pyrH_bact:Poorly characterized:Transcription:Salvage of nucleosides and nucleotides:Nucleotide and nucleoside interconversions:Purines, pyrimidines, nucleosides, and nucleotides:Transcription factors:Metabolism:Cellular processes and signaling:Information storage and processing:Biosynthesis and degradation of murein sacculus and peptidoglycan:Cell envelope:Translation factors:tRNA and rRNA base modification:Protein synthesis:RNA processing" 311 "Energy production and conversion:Glycosyltransferase:Serine/threonine protein phosphatase:Multimeric flavodoxin WrbA:Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes:Predicted pyrophosphatase:Uncharacterized protein conserved in bacteria:NAD+--asparagine ADP-ribosyltransferase:Cell wall/membrane/envelope biogenesis:General function prediction only:Function unknown:Signal transduction mechanisms:WXG100_ESAT6:Poorly characterized:Metabolism:Cellular processes and signaling" 312 "Energy production and conversion:Predicted Zn-dependent proteases and their inactivated homologs:Predicted choline kinase involved in LPS biosynthesis:2-polyprenylphenol hydroxylase and related flavodoxin oxidoreductases:ABC-type nitrate/sulfonate/bicarbonate transport system, permease component:Signal transduction histidine kinase:Predicted membrane metal-binding protein:Integral membrane protein, interacts with FtsH:Ribose 5-phosphate isomerase RpiB:Predicted xylanase/chitin deacetylase:Amino acid transporters:N-acetylglucosamine-1-phosphate uridyltransferase (contains nucleotidyltransferase and I-patch acetyltransferase domains):Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily:Uncharacterized conserved protein:Predicted small molecule binding protein (contains 3H domain):Site-specific recombinases, DNA invertase Pin homologs:Type II secretory pathway, pseudopilin PulG:Regulator of polyketide synthase expression:Uncharacterized protein conserved in bacteria:ABC-type sugar transport systems, ATPase components:Uncharacterized stress protein (general stress protein 26):Predicted integral membrane protein:Amino acid transport and metabolism:Carbohydrate transport and metabolism:Coenzyme transport and metabolism:Replication, recombination and repair:Cell wall/membrane/envelope biogenesis:Cell motility:Inorganic ion transport and metabolism:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:Function unknown:Signal transduction mechanisms:rpiB_lacA_lacB:2A0305:glmU:spore_CotS:Intracellular trafficking, secretion, and vesicular transport:Information storage and processing:Sporulation and germination:Cellular processes:Poorly characterized:Transport and binding proteins:Amino sugars:Central intermediary metabolism:Amino acids, peptides and amines:Metabolism:Cellular processes and signaling" 313 "Exoribonuclease R:ABC-type proline/glycine betaine transport systems, permease component:Transcriptional regulators:Amino acid transport and metabolism:Transcription:3_prime_RNase:Metabolism:Information storage and processing:Degradation of RNA:Transcription" 314 "Nucleotidyltransferase/DNA polymerase involved in DNA repair:ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component:Serine/threonine protein kinase:ABC-type dipeptide/oligopeptide/nickel transport systems, permease components:ABC-type dipeptide/oligopeptide/nickel transport systems, permease components:Beta-lactamase class C and other penicillin binding proteins:3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases:Alpha-L-arabinofuranosidase:ATP-dependent nuclease, subunit B:Uncharacterized conserved protein:Uncharacterized protein conserved in bacteria:Pectin methylesterase:Amino acid transport and metabolism:Carbohydrate transport and metabolism:Lipid transport and metabolism:Transcription:Replication, recombination and repair:Inorganic ion transport and metabolism:General function prediction only:Function unknown:Signal transduction mechanisms:oligo_HPY:addB_Gpos:Defense mechanisms:Metabolism:Cellular processes and signaling:Information storage and processing:Poorly characterized:Transport and binding proteins:DNA replication, recombination, and repair:DNA metabolism:Amino acids, peptides and amines" 315 "Pentose-5-phosphate-3-epimerase:tRNA and rRNA cytosine-C5-methylases:Ribosome recycling factor:NAD-dependent DNA ligase (contains BRCT domain type II):Predicted Zn-dependent proteases and their inactivated homologs:UDP-N-acetylglucosamine 2-epimerase:Glycosyltransferase:Zn-dependent hydrolases, including glyoxylases:ATPases with chaperone activity, ATP-binding subunit:Single-stranded DNA-specific exonuclease:Collagenase and related proteases:Predicted GTPases:DNA-directed RNA polymerase specialized sigma subunit:Predicted membrane GTPase involved in stress response:Predicted periplasmic solute-binding protein:Cell shape-determining protein:Galactose mutarotase and related enzymes:Uncharacterized conserved protein:DNA polymerase III, gamma/tau subunits:Outer membrane lipoprotein-sorting protein:Superfamily I DNA and RNA helicases:Predicted O-methyltransferase:Carbohydrate transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:Replication, recombination and repair:Cell wall/membrane/envelope biogenesis:Posttranslational modification, protein turnover, chaperones:General function prediction only:Function unknown:Signal transduction mechanisms:TIGR00157:mreC:small_GTP:wecB:TIGR00247:frr:rsmB:dnlj:recJ:rpe:ClpA:spore_sigmaK:Information storage and processing:Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides:Biosynthesis and degradation of murein sacculus and peptidoglycan:Cell envelope:General:Unknown function:Conserved:Hypothetical proteins:Sporulation and germination:Poorly characterized:Degradation of proteins, peptides, and glycopeptides:Protein fate:Translation factors:tRNA and rRNA base modification:Protein synthesis:DNA replication, recombination, and repair:DNA metabolism:Pentose phosphate pathway:Energy metabolism:Cellular processes:Metabolism:Cellular processes and signaling" 316 "Uncharacterized conserved protein:Phosphoglycerate dehydrogenase and related dehydrogenases:Thiamine monophosphate synthase:Thiamine biosynthesis protein ThiC:Translation elongation factors (GTPases):Glycerol uptake facilitator and related permeases (Major Intrinsic Protein Family):Cell division protein FtsI/penicillin-binding protein 2:Sugar (pentulose and hexulose) kinases:ABC-type polar amino acid transport system, ATPase component:Predicted polymerase, most proteins contain PALM domain, HD hydrolase domain and Zn-ribbon domain:NCAIR mutase (PurE)-related proteins:Uncharacterized enzyme of thiazole biosynthesis:Hydroxyethylthiazole kinase, sugar kinase family:L-arabinose isomerase:Predicted N-acetylglucosamine kinase:Response regulator with putative antiterminator output domain:Amino acid transport and metabolism:Carbohydrate transport and metabolism:Coenzyme transport and metabolism:Translation, ribosomal structure and biogenesis:Replication, recombination and repair:Cell wall/membrane/envelope biogenesis:General function prediction only:Function unknown:Signal transduction mechanisms:thiC:small_GTP:Metabolism:Cellular processes and signaling:Information storage and processing:Thiamine:Biosynthesis of cofactors, prosthetic groups, and carriers:General:Unknown function:Poorly characterized" 317 "Energy production and conversion:Superfamily I DNA and RNA helicases:Glycosyltransferase:Acetyltransferases:Amino acid transporters:ABC-type sulfate transport system, permease component:Signal transduction histidine kinase:Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain:ABC-type multidrug transport system, permease component:Uncharacterized low-complexity proteins:Predicted oxidoreductases of the aldo/keto reductase family:Predicted transcriptional regulators:NADH:flavin oxidoreductases, Old Yellow Enzyme family:Lysophospholipase:Amino acid transport and metabolism:Lipid transport and metabolism:Transcription:Replication, recombination and repair:Cell wall/membrane/envelope biogenesis:Posttranslational modification, protein turnover, chaperones:General function prediction only:Function unknown:Signal transduction mechanisms:Mo_ABC_porter:Defense mechanisms:Information storage and processing:Poorly characterized:Metabolism:Cellular processes and signaling" 318 "Energy production and conversion:Tryptophan synthase beta chain:Indole-3-glycerol phosphate synthase:Phosphoribosylanthranilate isomerase:Anthranilate/para-aminobenzoate synthases component I:Tryptophan synthase alpha chain:Dephospho-CoA kinase:Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain:Anthranilate/para-aminobenzoate synthases component II:Anthranilate phosphoribosyltransferase:ABC-type dipeptide transport system, periplasmic component:Alanine racemase:DNA-directed RNA polymerase specialized sigma subunit:Rubrerythrin:Predicted sugar phosphate isomerase:Amino acid transport and metabolism:Coenzyme transport and metabolism:Transcription:Cell wall/membrane/envelope biogenesis:Posttranslational modification, protein turnover, chaperones:General function prediction only:TIGR00152:trpA:trpB:TIGR00274:alr:trpE_most:trpG_papA:trpD:spore_sigmaE:Aromatic amino acid family:Metabolism:Poorly characterized:Information storage and processing:Biosynthesis and degradation of murein sacculus and peptidoglycan:Cell envelope:Pantothenate and coenzyme A:Biosynthesis of cofactors, prosthetic groups, and carriers:Cellular processes and signaling:Amino acid biosynthesis:Sporulation and germination:Cellular processes" 319 "Alanyl-tRNA synthetase:ATPases involved in chromosome partitioning:Predicted hydrolases of the HAD superfamily:Phosphopantetheine adenylyltransferase:N6-adenine-specific methylase:Cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes:HD-GYP domain:Permeases:Fucose 4-O-acetylase and related acetyltransferases:Predicted sensor domain:Cell cycle control, cell division, chromosome partitioning:Amino acid transport and metabolism:Carbohydrate transport and metabolism:Coenzyme transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:Replication, recombination and repair:General function prediction only:Signal transduction mechanisms:TIGR00095:cyt_tran_rel:alaS:eps_fam:Information storage and processing:Carbohydrates, organic alcohols, and acids:Transport and binding proteins:tRNA and rRNA base modification:tRNA aminoacylation:Protein synthesis:Poorly characterized:Metabolism:Cellular processes and signaling" 320 "Predicted Co/Zn/Cd cation transporters:Conserved domain frequently associated with peptide methionine sulfoxide reductase:Cytidine deaminase:Predicted xylanase/chitin deacetylase:Predicted transcriptional regulators:dTDP-D-glucose 4,6-dehydratase:Nitrogenase subunit NifH (ATPase):Cellulase M and related proteins:Beta-glucosidase-related glycosidases:Beta-lactamase class C and other penicillin binding proteins:Predicted transcriptional regulators:Formate/nitrite family of transporters:Predicted metal-dependent hydrolase of the TIM-barrel fold:Copper chaperone:Type II secretory pathway, ATPase PulE/Tfp pilus assembly pathway, ATPase PilB:Predicted membrane protein:Uncharacterized conserved protein:Bacterial surface proteins containing Ig-like domains:Nucleotide transport and metabolism:Carbohydrate transport and metabolism:Transcription:Cell wall/membrane/envelope biogenesis:Cell motility:Posttranslational modification, protein turnover, chaperones:Inorganic ion transport and metabolism:General function prediction only:Function unknown:TIGR00357:nifH:CDF:IV_pilin_GFxxxE:Intracellular trafficking, secretion, and vesicular transport:Defense mechanisms:Information storage and processing:Adaptations to atypical conditions:Cellular processes:Cations and iron carrying compounds:Transport and binding proteins:Cellular processes and signaling:Protein fate:Nitrogen fixation:Central intermediary metabolism:Metabolism:Poorly characterized:Protein and peptide secretion and trafficking" 321 "Acetylglutamate semialdehyde dehydrogenase:Ornithine carbamoyltransferase:Argininosuccinate synthase:Argininosuccinate lyase:ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component:Acetylglutamate kinase:ABC-type dipeptide/oligopeptide/nickel transport systems, permease components:ABC-type dipeptide transport system, periplasmic component:ABC-type amino acid transport/signal transduction systems, periplasmic component/domain:ABC-type dipeptide/oligopeptide/nickel transport systems, permease components:N-acetylglutamate synthase (N-acetylornithine aminotransferase):Transcriptional regulator/sugar kinase:Beta-glucosidase/6-phospho-beta-glucosidase/beta-galactosidase:Uncharacterized conserved protein:Ornithine/acetylornithine aminotransferase:Uncharacterized small protein:Amino acid transport and metabolism:Carbohydrate transport and metabolism:Transcription:Inorganic ion transport and metabolism:Function unknown:Signal transduction mechanisms:argG:ArgJ:orni_carb_tr:argD:argB:argH:oligo_HPY:argC:Transport and binding proteins:Metabolism:Poorly characterized:Cellular processes and signaling:Information storage and processing:Glutamate family:Amino acid biosynthesis:Amino acids, peptides and amines" 322 "ABC-type Mn2+/Zn2+ transport systems, permease components:Metal-dependent hydrolases of the beta-lactamase superfamily III:Transcriptional regulators:Transcriptional regulators:NTP pyrophosphohydrolases containing a Zn-finger, probably nucleic-acid-binding:Dipeptide/tripeptide permease:Predicted thioesterase involved in non-ribosomal peptide biosynthesis:Uncharacterized protein conserved in bacteria:Amino acid transport and metabolism:Transcription:Replication, recombination and repair:Inorganic ion transport and metabolism:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:Function unknown:yjdL_sub1_fam:RNase_Z:Metabolism:Information storage and processing:Amino acids, peptides and amines:Transport and binding proteins:RNA processing:Transcription:Poorly characterized" 323 "Histidinol phosphatase and related phosphatases:Phosphoheptose isomerase:Mannose-1-phosphate guanylyltransferase:Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis/translation initiation factor 2B, gamma/epsilon subunits (eIF-2Bgamma/eIF-2Bepsilon):Glycosyltransferases, probably involved in cell wall biogenesis:Predicted membrane protein involved in D-alanine export:FOG: GGDEF domain:Predicted kinase related to galactokinase and mevalonate kinase:Amino acid transport and metabolism:Carbohydrate transport and metabolism:Translation, ribosomal structure and biogenesis:Cell wall/membrane/envelope biogenesis:General function prediction only:Signal transduction mechanisms:GmhB_yaeD:GGDEF:Metabolism:Cellular processes and signaling:Information storage and processing:Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides:Cell envelope:Other:Signal transduction:Poorly characterized" 324 "Histidyl-tRNA synthetase:Methyl-accepting chemotaxis protein:ABC-type multidrug transport system, ATPase and permease components:Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1:Methylase of chemotaxis methyl-accepting proteins:Uncharacterized low-complexity proteins:Phosphotransferase system cellobiose-specific component IIB:Phosphotransferase system cellobiose-specific component IIA:Alpha-galactosidases/6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases:Predicted transcriptional regulators:Transcriptional regulators:Phospholipid-binding protein:Uncharacterized protein conserved in bacteria:Beta-glucosidase/6-phospho-beta-glucosidase/beta-galactosidase:Transcriptional antiterminator:Beta-mannanase:Carbohydrate transport and metabolism:Coenzyme transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:Cell motility:General function prediction only:Function unknown:Signal transduction mechanisms:hisS:TIGR00481:BGL:Defense mechanisms:Cellular processes and signaling:Information storage and processing:General:Poorly characterized:tRNA aminoacylation:Protein synthesis:Unknown function:Metabolism" 325 "Energy production and conversion:Ribosomal protein S16:Phosphotransacetylase:Uncharacterized flavoproteins:Thioredoxin reductase:Flavodoxins:Peroxiredoxin:3-hydroxyacyl-CoA dehydrogenase:Uncharacterized protein conserved in bacteria:Uncharacterized host factor I protein:Butyrate kinase:Cell division initiation protein:Cell cycle control, cell division, chromosome partitioning:Lipid transport and metabolism:Translation, ribosomal structure and biogenesis:Posttranslational modification, protein turnover, chaperones:General function prediction only:Function unknown:S16:thioredoxin:flav_short:Hfq:P_butyryltrans:butyr_kinase:DivI1A_domain:Energy metabolism:Other:Metabolism:Poorly characterized:Information storage and processing:Ribosomal proteins: synthesis and modification:Protein synthesis:Cellular processes and signaling:Regulatory functions:Fermentation:Electron transport" 326 "Energy production and conversion:Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis:Zn-dependent hydrolases, including glyoxylases:Thioredoxin reductase:Sugar kinases, ribokinase family:Single-stranded DNA-specific exonuclease:Signal transduction histidine kinase:Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain:Nitroreductase:2-keto-3-deoxy-6-phosphogluconate aldolase:Rad3-related DNA helicases:Uncharacterized low-complexity proteins:Predicted transcriptional regulators:ATPase related to the helicase subunit of the Holliday junction resolvase:Response regulator of the LytR/AlgR family:Carbohydrate transport and metabolism:Transcription:Replication, recombination and repair:Cell wall/membrane/envelope biogenesis:Posttranslational modification, protein turnover, chaperones:General function prediction only:Function unknown:Signal transduction mechanisms:recJ:eda:Metabolism:Cellular processes and signaling:Information storage and processing:DNA replication, recombination, and repair:DNA metabolism:Entner-Doudoroff:Energy metabolism:Poorly characterized" 327 "Energy production and conversion:Seryl-tRNA synthetase:Predicted dehydrogenase:Nitroreductase:ABC-type polysaccharide/polyol phosphate transport system, ATPase component:Putative NADPH-quinone reductase (modulator of drug activity B):SAM-dependent methyltransferases related to tRNA (uracil-5-)-methyltransferase:Tfp pilus assembly protein PilF:Uncharacterized protein conserved in bacteria:Carbohydrate transport and metabolism:Translation, ribosomal structure and biogenesis:Cell wall/membrane/envelope biogenesis:Cell motility:General function prediction only:Function unknown:serS:rumA:Intracellular trafficking, secretion, and vesicular transport:Metabolism:Cellular processes and signaling:Information storage and processing:tRNA and rRNA base modification:tRNA aminoacylation:Protein synthesis:Poorly characterized" 328 "Energy production and conversion:Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase:IMP dehydrogenase/GMP reductase:Predicted dehydrogenase:6-pyruvoyl-tetrahydropterin synthase:Nitroreductase:FOG: CheY-like receiver:ABC-type proline/glycine betaine transport systems, permease component:Amino acid transport and metabolism:Nucleotide transport and metabolism:Coenzyme transport and metabolism:General function prediction only:Signal transduction mechanisms:2A0105:IMP_dehydrog:6_pyr_pter_rel:Carbohydrates, organic alcohols, and acids:Transport and binding proteins:Purine ribonucleotide biosynthesis:Purines, pyrimidines, nucleosides, and nucleotides:Cellular processes and signaling:Metabolism:Poorly characterized" 329 "Pentose-5-phosphate-3-epimerase:Aspartyl-tRNA synthetase:Guanylate kinase:Protein chain release factor A:Methionyl-tRNA formyltransferase:Predicted tRNA(5-methylaminomethyl-2-thiouridylate) methyltransferase, contains the PP-loop ATPase domain:Serine/threonine protein kinase:FKBP-type peptidyl-prolyl cis-trans isomerase (trigger factor):Preprotein translocase subunit SecA (ATPase, RNA helicase):Ribose 5-phosphate isomerase RpiB:Predicted Fe-S-cluster redox enzyme:Predicted Zn-dependent peptidases, insulinase-like:Aspartate ammonia-lyase:UDP-glucose 4-epimerase:Cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes:Predicted GTPases:D-alanine-D-alanine ligase and related ATP-grasp enzymes:Uncharacterized protein conserved in bacteria:Predicted nucleic-acid-binding protein (contains the HHH domain):Putative homoserine kinase type II (protein kinase fold):Predicted Zn-dependent protease:DNA polymerase III, gamma/tau subunits:Predicted O-methyltransferase:Signal transduction histidine kinase:Amino acid transport and metabolism:Nucleotide transport and metabolism:Carbohydrate transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:Replication, recombination and repair:Cell wall/membrane/envelope biogenesis:Posttranslational modification, protein turnover, chaperones:General function prediction only:Function unknown:Signal transduction mechanisms:prfB:TIGR00048:tig:sensory_box:small_GTP:trmU:aspS_bact:fmt:rpiB_lacA_lacB:secA:rpe:galE:D_ala_D_alaTIGR:guanyl_kin:Intracellular trafficking, secretion, and vesicular transport:Purines, pyrimidines, nucleosides, and nucleotides:General:Cell envelope:Biosynthesis and degradation of murein sacculus and peptidoglycan:Information storage and processing:Cellular processes and signaling:Metabolism:Poorly characterized:Protein and peptide secretion and trafficking:Protein folding and stabilization:Protein fate:Translation factors:tRNA and rRNA base modification:tRNA aminoacylation:Protein synthesis:Small molecule interactions:Regulatory functions:Nucleotide and nucleoside interconversions:Unknown function:Sugars:Pentose phosphate pathway:Energy metabolism" 330 "Glucan phosphorylase:Glycosidases:Membrane proteins related to metalloendopeptidases:Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases):Subtilisin-like serine proteases:Transcriptional regulators:Activator of 2-hydroxyglutaryl-CoA dehydratase (HSP70-class ATPase domain):Putative homoserine kinase type II (protein kinase fold):Uncharacterized protein conserved in bacteria:Uncharacterized protein conserved in bacteria:Iron only hydrogenase large subunit, C-terminal domain:Bacterial surface proteins containing Ig-like domains:Carbohydrate transport and metabolism:Lipid transport and metabolism:Transcription:Cell wall/membrane/envelope biogenesis:Cell motility:Posttranslational modification, protein turnover, chaperones:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:Function unknown:CoA_E_activ:more_P_ylases:spore_II_P:spore_CotS:Information storage and processing:Sporulation and germination:Cellular processes:Metabolism:Poorly characterized:Cellular processes and signaling" 331 "Imidazoleglycerol-phosphate dehydratase:Phosphoribosyl-ATP pyrophosphohydrolase:Transaldolase:Predicted Fe-S oxidoreductases:Amino acid transport and metabolism:Carbohydrate transport and metabolism:General function prediction only:fsa_talC_mipB:spore_YyaC:histidine_hisI:rSAM_NirJ2:Poorly characterized:Sporulation and germination:Amino acid biosynthesis:Pentose phosphate pathway:Energy metabolism:Cellular processes:Histidine family:Metabolism" 332 "Energy production and conversion:Asp-tRNAAsn/Glu-tRNAGln amidotransferase B subunit (PET112 homolog):Lactoylglutathione lyase and related lyases:Protease subunit of ATP-dependent Clp proteases:Site-specific recombinases, DNA invertase Pin homologs:Beta-glucosidase/6-phospho-beta-glucosidase/beta-galactosidase:Butyrate kinase:Uncharacterized protein conserved in bacteria:Transcriptional antiterminator:Phage terminase-like protein, large subunit:Phage-related protein:Amino acid transport and metabolism:Carbohydrate transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:Replication, recombination and repair:Posttranslational modification, protein turnover, chaperones:General function prediction only:Function unknown:gatB:portal_HK97:butyr_kinase:Intracellular trafficking, secretion, and vesicular transport:Cellular processes and signaling:Information storage and processing:Prophage functions:Mobile and extrachromosomal element functions:tRNA aminoacylation:Protein synthesis:Fermentation:Energy metabolism:Metabolism:Poorly characterized" 333 "Superfamily II DNA and RNA helicases:Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily):Metal-dependent hydrolases of the beta-lactamase superfamily III:Transcriptional regulator:Membrane-associated lipoprotein involved in thiamine biosynthesis:Deoxyinosine 3'endonuclease (endonuclease V):Predicted membrane protein/domain:FOG: FHA domain:Type II secretory pathway, pseudopilin PulG:FOG: EAL domain:Predicted drug exporters of the RND superfamily:Uncharacterized protein conserved in bacteria:Capsular polysaccharide biosynthesis protein:Carbohydrate transport and metabolism:Coenzyme transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:Replication, recombination and repair:Cell wall/membrane/envelope biogenesis:Cell motility:General function prediction only:Function unknown:Signal transduction mechanisms:GGDEF:IV_pilin_GFxxxE:T7_EssCb_Firm:Intracellular trafficking, secretion, and vesicular transport:Cellular processes and signaling:Information storage and processing:Other:Signal transduction:Protein and peptide secretion and trafficking:Protein fate:Metabolism:Poorly characterized" 334 "Energy production and conversion:Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase]:Ketol-acid reductoisomerase:3-isopropylmalate dehydratase large subunit:3-isopropylmalate dehydratase small subunit:Isopropylmalate/homocitrate/citramalate synthases:Dihydroxyacid dehydratase/phosphogluconate dehydratase:Isocitrate/isopropylmalate dehydrogenase:Predicted membrane protein, hemolysin III homolog:Uncharacterized protein conserved in bacteria:Uncharacterized protein conserved in bacteria:Amino acid transport and metabolism:Carbohydrate transport and metabolism:Coenzyme transport and metabolism:General function prediction only:Function unknown:ilvD:acolac_lg:leuB:ilvC:DegV:LeuA_rel:hlyIII:hacA_fam:leud:TIGR04076:General:Poorly characterized:Metabolism:Pyruvate family:Amino acid biosynthesis:Unknown function" 335 "Energy production and conversion:GTPases - translation elongation factors:F0F1-type ATP synthase, alpha subunit:DNA-directed RNA polymerase, beta subunit/140 kD subunit:DNA-directed RNA polymerase, beta' subunit/160 kD subunit:3-phosphoglycerate kinase:Excinuclease ATPase subunit:Ribosomal protein S14:Ribosomal protein L15:Protein chain release factor A:F0F1-type ATP synthase, gamma subunit:Mismatch repair ATPase (MutS family):Acetate kinase:Replicative DNA helicase:F0F1-type ATP synthase, epsilon subunit (mitochondrial delta subunit):Translation elongation factors (GTPases):Helicase subunit of the DNA excision repair complex:Adenylate kinase and related kinases:dsRNA-specific ribonuclease:Predicted Zn-dependent peptidases:F0F1-type ATP synthase, subunit b:F0F1-type ATP synthase, delta subunit (mitochondrial oligomycin sensitivity protein):Predicted xylanase/chitin deacetylase:Predicted kinase related to dihydroxyacetone kinase:Nucleotide transport and metabolism:Carbohydrate transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:Replication, recombination and repair:General function prediction only:ackA:prfB:small_GTP:uvra:uvrb:DnaB:atpA:rplO_bact:ATP_synt_b:ATP_synt_delta:ATPsyn_F1gamma:ATP_synt_epsi:adk:rpoB:RNaseIII:rpoC_TIGR:YloV:RNA processing:DNA-dependent RNA polymerase:Transcription:DNA replication, recombination, and repair:DNA metabolism:Poorly characterized:Purines, pyrimidines, nucleosides, and nucleotides:Fermentation:ATP-proton motive force interconversion:Energy metabolism:Nucleotide and nucleoside interconversions:Metabolism:Information storage and processing:General:Unknown function:Translation factors:Ribosomal proteins: synthesis and modification:Protein synthesis" 336 "Exopolyphosphatase:Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis:ATPases involved in chromosome partitioning:ATP-dependent Lon protease, bacterial type:Predicted membrane protein:Site-specific recombinases, DNA invertase Pin homologs:Flp pilus assembly protein TadC:Sulfur transfer protein involved in thiamine biosynthesis:Sugar phosphate permease:ABC-type transport system, involved in lipoprotein release, permease component:Flp pilus assembly protein, ATPase CpaF:Cell cycle control, cell division, chromosome partitioning:Nucleotide transport and metabolism:Carbohydrate transport and metabolism:Coenzyme transport and metabolism:Replication, recombination and repair:Cell wall/membrane/envelope biogenesis:Cell motility:Posttranslational modification, protein turnover, chaperones:Inorganic ion transport and metabolism:Function unknown:lon:thiS:spore_YyaC:exo_poly_only:T7_esaA_Nterm:Intracellular trafficking, secretion, and vesicular transport:Phosphorus compounds:Central intermediary metabolism:Biosynthesis of cofactors, prosthetic groups, and carriers:Metabolism:Cellular processes and signaling:Information storage and processing:Thiamine:Poorly characterized:Sporulation and germination:Cellular processes:Degradation of proteins, peptides, and glycopeptides:Protein fate" 337 "ABC-type phosphate transport system, periplasmic component:(acyl-carrier-protein) S-malonyltransferase:Nitrogen regulatory protein PII:Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases):Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities:Thymidine kinase:Uncharacterized conserved protein:Uncharacterized protein conserved in bacteria:NAD+--asparagine ADP-ribosyltransferase:Amino acid transport and metabolism:Nucleotide transport and metabolism:Lipid transport and metabolism:Inorganic ion transport and metabolism:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:Function unknown:Signal transduction mechanisms:fabD:TIGR00266:3oxo_ACP_reduc:ptsS_2:prismane_assoc:Hypothetical proteins:Anions:Transport and binding proteins:Biosynthesis:Fatty acid and phospholipid metabolism:Electron transport:Energy metabolism:Metabolism:Poorly characterized:Cellular processes and signaling:Conserved" 338 "Energy production and conversion:Translation elongation factors (GTPases):Predicted hydrolases of the HAD superfamily:ABC-type antimicrobial peptide transport system, permease component:Methyl-accepting chemotaxis protein:Membrane-fusion protein:Lactate dehydrogenase and related dehydrogenases:Sugar phosphate isomerases/epimerases:Predicted dithiol-disulfide isomerase involved in polyketide biosynthesis:Arabinose efflux permease:Predicted enzyme involved in methoxymalonyl-ACP biosynthesis:Predicted unsaturated glucuronyl hydrolase involved in regulation of bacterial surface properties, and related proteins:Uncharacterized conserved protein:Predicted membrane protein:Uncharacterized protein conserved in bacteria:Carbohydrate transport and metabolism:Coenzyme transport and metabolism:Translation, ribosomal structure and biogenesis:Cell wall/membrane/envelope biogenesis:Cell motility:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:Function unknown:Signal transduction mechanisms:Cof-subfamily:small_GTP:HAD-SF-IIIC:RND_mfp:Defense mechanisms:Information storage and processing:General:Enzymes of unknown specificity:Poorly characterized:Unknown substrate:Transport and binding proteins:Unknown function:Metabolism:Cellular processes and signaling" 339 "Chemotaxis protein histidine kinase and related kinases:Chemotaxis signal transduction protein:Flagellar hook-associated protein:Predicted polymerase, most proteins contain PALM domain, HD hydrolase domain and Zn-ribbon domain:Uncharacterized flagellar protein FlaG:Flagellin and related hook-associated proteins:Flagellar capping protein:Methylase of chemotaxis methyl-accepting proteins:Flagellin-specific chaperone FliS:Carbon storage regulator (could also regulate swarming and quorum sensing):Uncharacterized protein conserved in bacteria:Chemotaxis protein CheC, inhibitor of MCP methylation:Flagellar motor switch protein:Chemotaxis protein; stimulates methylation of MCP proteins:Chemotaxis response regulator containing a CheY-like receiver domain and a methylesterase domain:Replication, recombination and repair:Cell motility:Posttranslational modification, protein turnover, chaperones:Function unknown:Signal transduction mechanisms:csrA:fliS:fliM_switch:flgK_ends:flg_new:flagell_flgL:Intracellular trafficking, secretion, and vesicular transport:RNA interactions:Poorly characterized:Regulatory functions:Cellular processes and signaling:Information storage and processing:Chemotaxis and motility:Cellular processes" 340 "2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase:Molybdopterin biosynthesis enzyme:ABC-type sugar transport system, permease component:Predicted dehydrogenases and related proteins:Sugar (pentulose and hexulose) kinases:ABC-type antimicrobial peptide transport system, ATPase component:Beta-glucosidase-related glycosidases:Alpha-glucosidases, family 31 of glycosyl hydrolases:ABC-type sugar transport system, periplasmic component:Transcriptional regulator/sugar kinase:Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain:Sugar phosphate permease:Beta-glucanase/Beta-glucan synthetase:L-fucose isomerase and related proteins:Beta-glucosidase/6-phospho-beta-glucosidase/beta-galactosidase:Signal transduction histidine kinase:Carbohydrate transport and metabolism:Coenzyme transport and metabolism:Lipid transport and metabolism:Transcription:General function prediction only:Signal transduction mechanisms:ispF:molyb_syn:SP:XylB:Defense mechanisms:Information storage and processing:Other:Biosynthesis of cofactors, prosthetic groups, and carriers:Poorly characterized:Transport and binding proteins:Sugars:Energy metabolism:Carbohydrates, organic alcohols, and acids:Metabolism:Cellular processes and signaling" 341 "Acyl carrier protein:Spermidine synthase:Acetyltransferases:ATPases involved in chromosome partitioning:Multimeric flavodoxin WrbA:Transcriptional regulator:Predicted transcriptional regulators:Adenosine deaminase:Predicted membrane protein:Phosphotransferase system IIA components:Methylase involved in ubiquinone/menaquinone biosynthesis:SAM-dependent methyltransferases related to tRNA (uracil-5-)-methyltransferase:Barstar, RNAse (barnase) inhibitor:Cell wall hydrolyses involved in spore germination:Uncharacterized conserved protein, contains double-stranded beta-helix domain:Uncharacterized stress protein (general stress protein 26):Uncharacterized conserved protein:Uncharacterized conserved protein:Cell cycle control, cell division, chromosome partitioning:Amino acid transport and metabolism:Nucleotide transport and metabolism:Carbohydrate transport and metabolism:Coenzyme transport and metabolism:Lipid transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:Cell wall/membrane/envelope biogenesis:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:Function unknown:speE:rumA:PTBA:aden_deam:spore_YtaF:spore_SleB:Signal transduction:Sporulation and germination:Cellular processes:tRNA and rRNA base modification:Protein synthesis:Polyamine biosynthesis:Central intermediary metabolism:Metabolism:Poorly characterized:Cellular processes and signaling:Information storage and processing:PTS" 342 "Energy production and conversion:Serine-pyruvate aminotransferase/archaeal aspartate aminotransferase:Mannitol-1-phosphate/altronate dehydrogenases:Glycerol kinase:ABC-type antimicrobial peptide transport system, permease component:Methyl-accepting chemotaxis protein:ABC-type antimicrobial peptide transport system, ATPase component:Predicted glycosyltransferases:Transcriptional regulators of sugar metabolism:Phosphotransferase system cellobiose-specific component IIC:Predicted transcriptional regulators:Phosphotransferase system, mannitol-specific IIBC component:Transcriptional antiterminator:Mannitol/fructose-specific phosphotransferase system, IIA domain:NAD+--asparagine ADP-ribosyltransferase:Plasmid rolling circle replication initiator protein and truncated derivatives:Amino acid transport and metabolism:Carbohydrate transport and metabolism:Transcription:Replication, recombination and repair:Cell motility:General function prediction only:Signal transduction mechanisms:lac_pts_IIC:mtlA:glycerol_kin:Defense mechanisms:Cellular processes and signaling:Information storage and processing:PTS:Poorly characterized:Other:Energy metabolism:Signal transduction:Metabolism" 343 "Energy production and conversion:Serine-pyruvate aminotransferase/archaeal aspartate aminotransferase:3-methyladenine DNA glycosylase/8-oxoguanine DNA glycosylase:Peptide methionine sulfoxide reductase:3-hexulose-6-phosphate synthase and related proteins:Phosphotransacetylase:Acetate kinase:Dihydrodipicolinate reductase:Dihydrodipicolinate synthase/N-acetylneuraminate lyase:Uncharacterized conserved protein:ABC-type antimicrobial peptide transport system, permease component:ABC-type multidrug transport system, permease component:NAD-dependent protein deacetylases, SIR2 family:Lactate dehydrogenase and related dehydrogenases:ABC-type antimicrobial peptide transport system, ATPase component:Protein chain release factor B:Uncharacterized protein, possibly involved in motility:Transcriptional regulators:Beta-glucosidase/6-phospho-beta-glucosidase/beta-galactosidase:Endoglucanase:Uncharacterized protein conserved in bacteria:ABC-type transport system, involved in lipoprotein release, permease component:NAD+--asparagine ADP-ribosyltransferase:Amino acid transport and metabolism:Carbohydrate transport and metabolism:Coenzyme transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:Replication, recombination and repair:Cell wall/membrane/envelope biogenesis:Cell motility:Posttranslational modification, protein turnover, chaperones:General function prediction only:Function unknown:Signal transduction mechanisms:ackA:dapB:msrA:pta:dapA:CofD_related:release_prfH:Defense mechanisms:Conserved:Hypothetical proteins:Adaptations to atypical conditions:Cellular processes:Poorly characterized:Protein synthesis:Fermentation:Energy metabolism:Translation factors:Metabolism:Cellular processes and signaling:Information storage and processing:Aspartate family:Amino acid biosynthesis" 344 "3-oxoacyl-[acyl-carrier-protein] synthase III:Methyl-accepting chemotaxis protein:ABC-type Mn/Zn transport systems, ATPase component:Transcriptional regulator:Transcriptional regulators:Predicted transcriptional regulator:Predicted membrane protein:Cobalamin biosynthesis protein CbiK, Co2+ chelatase:Bacterial surface proteins containing Ig-like domains:Coenzyme transport and metabolism:Lipid transport and metabolism:Transcription:Cell motility:Inorganic ion transport and metabolism:Function unknown:Signal transduction mechanisms:integ_TIGR01906:Information storage and processing:Poorly characterized:Metabolism:Cellular processes and signaling" 345 "Energy production and conversion:Undecaprenyl pyrophosphate synthase:Acetyltransferase (isoleucine patch superfamily):Superfamily II DNA helicase:Pseudouridylate synthases, 23S RNA-specific:ABC-type dipeptide/oligopeptide/nickel transport systems, permease components:Predicted permeases:Membrane carboxypeptidase (penicillin-binding protein):Pyruvate carboxylase:Uncharacterized conserved protein:Uncharacterized conserved protein:Transcriptional regulators:Uncharacterized protein conserved in bacteria:Uncharacterized protein conserved in bacteria:Predicted transcriptional regulator:Uncharacterized protein conserved in bacteria:Galactose-1-phosphate uridyltransferase:Amino acid transport and metabolism:Carbohydrate transport and metabolism:Lipid transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:Replication, recombination and repair:Cell wall/membrane/envelope biogenesis:Inorganic ion transport and metabolism:General function prediction only:Function unknown:rluA_subfam:uppS:recQ_fam:pyruv_carbox:galT_2:PBP_1a_fam:M6dom_TIGR03296:Protein synthesis:Poorly characterized:DNA metabolism:Sugars:Glycolysis/gluconeogenesis:Energy metabolism:DNA replication, recombination, and repair:Metabolism:Cellular processes and signaling:Information storage and processing:Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides:Biosynthesis and degradation of murein sacculus and peptidoglycan:Cell envelope:tRNA and rRNA base modification" 346 "Mg2+ and Co2+ transporters:Signal transduction histidine kinase:ABC-type multidrug transport system, permease component:ABC-type multidrug transport system, ATPase component:ABC-type multidrug transport system, ATPase and permease components:Predicted glycosyltransferases:Imidazolonepropionase and related amidohydrolases:Transcriptional regulators of sugar metabolism:Transcriptional regulators:Uncharacterized proteins, homologs of microcin C7 resistance protein MccF:Uncharacterized membrane protein, possible Na+ channel or pump:Cell division protein:DnaJ-class molecular chaperone:Signal transduction histidine kinase:Chloramphenicol O-acetyltransferase:Cell cycle control, cell division, chromosome partitioning:Carbohydrate transport and metabolism:Transcription:Posttranslational modification, protein turnover, chaperones:Inorganic ion transport and metabolism:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:Signal transduction mechanisms:corA:Defense mechanisms:Cellular processes and signaling:Information storage and processing:Cations and iron carrying compounds:Transport and binding proteins:Poorly characterized:Metabolism" 347 "Energy production and conversion:Signal transduction histidine kinase:Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain:ABC-type antimicrobial peptide transport system, ATPase component:Deoxyinosine 3'endonuclease (endonuclease V):Predicted metal-dependent hydrolase of the TIM-barrel fold:Nitrogenase molybdenum-iron protein, alpha and beta chains:Retron-type reverse transcriptase:Type IV secretory pathway, VirB4 components:ABC-type transport system, involved in lipoprotein release, permease component:NAD+--asparagine ADP-ribosyltransferase:Transcription:Replication, recombination and repair:Cell wall/membrane/envelope biogenesis:General function prediction only:Signal transduction mechanisms:nifD:nifE:Intracellular trafficking, secretion, and vesicular transport:Defense mechanisms:Metabolism:Cellular processes and signaling:Poorly characterized:Nitrogen fixation:Central intermediary metabolism:Information storage and processing" 348 "Aspartate/tyrosine/aromatic aminotransferase:Pyruvate kinase:Na+-driven multidrug efflux pump:Parvulin-like peptidyl-prolyl isomerase:Adenylate cyclase, class 2 (thermophilic):Nicotinic acid phosphoribosyltransferase:Uncharacterized protein conserved in bacteria:Transcriptional regulators:Cyclopropane fatty acid synthase and related methyltransferases:Predicted membrane protein:Aminoglycoside N3'-acetyltransferase:Dipeptide/tripeptide permease:Uncharacterized protein conserved in bacteria:Uncharacterized protein conserved in bacteria:Amino acid transport and metabolism:Nucleotide transport and metabolism:Carbohydrate transport and metabolism:Coenzyme transport and metabolism:Transcription:Cell wall/membrane/envelope biogenesis:Posttranslational modification, protein turnover, chaperones:Function unknown:matE:yjdL_sub1_fam:pyruv_kin:NAPRTase_put:TIGR02452:Defense mechanisms:Pyridine nucleotides:Biosynthesis of cofactors, prosthetic groups, and carriers:Other:Poorly characterized:Transport and binding proteins:Glycolysis/gluconeogenesis:Energy metabolism:Amino acids, peptides and amines:Metabolism:Cellular processes and signaling:Information storage and processing" 349 "Adenine-specific DNA methylase:ABC-type multidrug transport system, ATPase component:Predicted transcriptional regulator:Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain:Predicted double-stranded RNA/RNA-DNA hybrid binding protein:Uncharacterized protein conserved in bacteria:Uncharacterized protein conserved in bacteria:Uncharacterized protein conserved in bacteria:NAD+--asparagine ADP-ribosyltransferase:Transcription:Replication, recombination and repair:General function prediction only:Function unknown:Signal transduction mechanisms:rrf2_super:WXG100_ESAT6:Defense mechanisms:Poorly characterized:Cellular processes and signaling:Information storage and processing:General:Unknown function" 350 "Energy production and conversion:Geranylgeranyl pyrophosphate synthase:Predicted rRNA methylase (SpoU class):Glycerol-3-phosphate dehydrogenase:L-asparaginase/archaeal Glu-tRNAGln amidotransferase subunit D:Ribosomal protein S1:Phosphatidylglycerophosphate synthase:UDP-N-acetylglucosamine enolpyruvyl transferase:Transcription termination factor:dTDP-4-dehydrorhamnose reductase:Predicted GTPases:Predicted glycosyltransferases:Metal-dependent hydrolases of the beta-lactamase superfamily I:Fe-S oxidoreductase, related to NifB/MoaA family:Lipid A core - O-antigen ligase and related enzymes:Amino acid transport and metabolism:Coenzyme transport and metabolism:Lipid transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:Cell wall/membrane/envelope biogenesis:General function prediction only:ispH_lytB:small_GTP:pgsA:murA:rmlD:nusB:spore_yabQ:Metabolism:Cellular processes and signaling:Information storage and processing:Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides:Biosynthesis and degradation of murein sacculus and peptidoglycan:Cell envelope:Other:Biosynthesis of cofactors, prosthetic groups, and carriers:Poorly characterized:Unknown function:Sporulation and germination:Cellular processes:Transcription factors:Transcription:Biosynthesis:Fatty acid and phospholipid metabolism:General" 351 "Cytidylate kinase:Glycosyltransferase:Predicted hydrolases of the HAD superfamily:Collagenase and related proteases:DNA repair photolyase:Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain:Signal transduction histidine kinase regulating citrate/malate metabolism:Signal transduction histidine kinase:Nucleotide transport and metabolism:Transcription:Replication, recombination and repair:Cell wall/membrane/envelope biogenesis:Posttranslational modification, protein turnover, chaperones:General function prediction only:Signal transduction mechanisms:cmk:Cof-subfamily:Metabolism:Cellular processes and signaling:Information storage and processing:Enzymes of unknown specificity:Unknown function:Nucleotide and nucleoside interconversions:Purines, pyrimidines, nucleosides, and nucleotides:Poorly characterized" 352 "Energy production and conversion:Ribosomal protein S15P/S13E:CDP-diglyceride synthetase:Lipoprotein signal peptidase:2-methylthioadenine synthetase:Holliday junction resolvasome, DNA-binding subunit:Sugar phosphate isomerases/epimerases:Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily:Uncharacterized protein conserved in bacteria:Fe-S oxidoreductase, related to NifB/MoaA family:D-alanyl-D-alanine carboxypeptidase:Predicted transcriptional regulators:Signal transduction histidine kinase, nitrogen specific:Carbohydrate transport and metabolism:Lipid transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:Replication, recombination and repair:Cell wall/membrane/envelope biogenesis:Function unknown:Signal transduction mechanisms:TIGR00046:lspA:ruvA:TIGR00089:S15_bact:Intracellular trafficking, secretion, and vesicular transport:Protein and peptide secretion and trafficking:Protein fate:tRNA and rRNA base modification:Ribosomal proteins: synthesis and modification:Protein synthesis:DNA replication, recombination, and repair:DNA metabolism:Information storage and processing:Cellular processes and signaling:Metabolism:Poorly characterized" 353 "Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase:ATPases involved in chromosome partitioning:Superfamily II DNA/RNA helicases, SNF2 family:rRNA methylases:Serine/threonine protein phosphatase:Predicted xylanase/chitin deacetylase:Alanine racemase:Methyl-accepting chemotaxis protein:ABC-type antimicrobial peptide transport system, ATPase component:Predicted transcriptional regulators:DNA polymerase III, alpha subunit (gram-positive type):Predicted O-methyltransferase:Signal transduction histidine kinase:Predicted kinase:Predicted membrane protein:Glycopeptide antibiotics resistance protein:Cell cycle control, cell division, chromosome partitioning:Carbohydrate transport and metabolism:Coenzyme transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:Replication, recombination and repair:Cell wall/membrane/envelope biogenesis:Cell motility:General function prediction only:Function unknown:Signal transduction mechanisms:HMP-P_kinase:HDIG:alr:dnaq:Defense mechanisms:Information storage and processing:Biosynthesis and degradation of murein sacculus and peptidoglycan:Cell envelope:Poorly characterized:Biosynthesis of cofactors, prosthetic groups, and carriers:Degradation of DNA:DNA metabolism:Thiamine:Metabolism:Cellular processes and signaling" 354 "Predicted hydrolases of the HAD superfamily:Signal transduction histidine kinase:ABC-type multidrug transport system, ATPase component:Cellulase M and related proteins:Uncharacterized conserved protein:Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain:Sugar diacid utilization regulator:Carbohydrate transport and metabolism:Transcription:General function prediction only:Function unknown:Signal transduction mechanisms:Cof-subfamily:TIGR00266:Defense mechanisms:Metabolism:Cellular processes and signaling:Information storage and processing:Enzymes of unknown specificity:Unknown function:Conserved:Hypothetical proteins:Poorly characterized" 355 "Glycosyltransferase:tRNA nucleotidyltransferase/poly(A) polymerase:Flagellar biosynthesis pathway, component FlhA:Flagellar biosynthesis pathway, component FliP:Flagellin and related hook-associated proteins:Flagellar biosynthesis pathway, component FlhB:Flagellar basal body-associated protein:Flagellar hook capping protein:Flagellar biosynthesis pathway, component FliQ:Uncharacterized protein conserved in bacteria:Negative regulator of flagellin synthesis (anti-sigma28 factor):Flagellar biogenesis protein:Predicted enzyme involved in methoxymalonyl-ACP biosynthesis:Uncharacterized protein conserved in bacteria:Spore coat polysaccharide biosynthesis protein, predicted glycosyltransferase:Uncharacterized protein conserved in bacteria with an aminopeptidase-like domain:Uncharacterized protein conserved in bacteria:Translation, ribosomal structure and biogenesis:Transcription:Cell wall/membrane/envelope biogenesis:Cell motility:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:Function unknown:flhB:fliP:FlhA:fliQ:HAD-SF-IIIC:FliO_TIGR:PseG:FlgM_jcvi:Intracellular trafficking, secretion, and vesicular transport:Cellular processes:Chemotaxis and motility:Information storage and processing:Cellular processes and signaling:Metabolism:Poorly characterized" 356 "Short-chain dehydrogenases of various substrate specificities:3-oxoacyl-[acyl-carrier-protein] synthase III:Aspartate/tyrosine/aromatic aminotransferase:Threonyl-tRNA synthetase:Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily):Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases:cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases:Predicted transcriptional regulators:Predicted acetyltransferases and hydrolases with the alpha/beta hydrolase fold:ATPases involved in chromosome partitioning:Metal-dependent hydrolases of the beta-lactamase superfamily III:Transcriptional regulators:Predicted aminopeptidases:DNA polymerase III, gamma/tau subunits:Predicted transcriptional regulator:NAD+--asparagine ADP-ribosyltransferase:Cell cycle control, cell division, chromosome partitioning:Amino acid transport and metabolism:Lipid transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:Replication, recombination and repair:General function prediction only:Signal transduction mechanisms:thrS:efflux_EmrB:fabH:dipeptidaselike:dnaX_nterm:T7SS_EssA_Firm:Protein fate:Poorly characterized:Protein synthesis:DNA replication, recombination, and repair:DNA metabolism:Biosynthesis:Fatty acid and phospholipid metabolism:tRNA aminoacylation:Metabolism:Cellular processes and signaling:Information storage and processing:Other:Transport and binding proteins:Protein and peptide secretion and trafficking" 357 "3-hexulose-6-phosphate synthase and related proteins:Methyl-accepting chemotaxis protein:Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities:Beta-fructosidases (levanase/invertase):L-serine deaminase:Cation transport ATPase:Methylase involved in ubiquinone/menaquinone biosynthesis:Amino acid transport and metabolism:Carbohydrate transport and metabolism:Coenzyme transport and metabolism:Cell motility:Inorganic ion transport and metabolism:Signal transduction mechanisms:TIGR00003:sda_alpha:Cellular processes and signaling:Cations and iron carrying compounds:Transport and binding proteins:Glycolysis/gluconeogenesis:Energy metabolism:Metabolism" 358 "Ribosomal protein L4:Ribosomal protein L22:Ribosomal protein S3:Ribosomal protein L14:Ribosomal protein S8:Ribosomal protein L6P/L9E:Ribosomal protein S5:Ribosomal protein S13:Ribosomal protein S17:Ribosomal protein L16/L10E:Ribosomal protein L29:Ribosomal protein L18:Ribosomal protein S4 and related proteins:ABC-type cobalt transport system, ATPase component:Ribosomal protein L30/L7E:Ribosomal protein L14E/L6E/L27E:Translation, ribosomal structure and biogenesis:Inorganic ion transport and metabolism:L29:L18_bact:rpsC_bact:rpsD_bact:rpsE_bact:rpmJ_bact:rplV_bact:rplN_bact:rplP_bact:rpmD_bact:bact_S13:S17_bact:L6_bact:rplD_bact:Metabolism:Protein synthesis:Ribosomal proteins: synthesis and modification:Information storage and processing" 359 "Energy production and conversion:Predicted rRNA methylase (SpoU class):Pyruvate kinase:ABC-type antimicrobial peptide transport system, permease component:Uncharacterized membrane-associated protein:Predicted permease:UDP-N-acetylmuramate-alanine ligase:ABC-type antimicrobial peptide transport system, ATPase component:Protein chain release factor B:Glycosyltransferases, probably involved in cell wall biogenesis:Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific:Transcriptional regulator:Chemotaxis protein CheC, inhibitor of MCP methylation:Transcriptional regulator, contains sigma factor-related N-terminal domain:Endoglucanase:Butyrate kinase:ABC-type transport system, involved in lipoprotein release, permease component:Flagellar basal body rod protein:Bacterial surface proteins containing Ig-like domains:Carbohydrate transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:Cell wall/membrane/envelope biogenesis:Cell motility:General function prediction only:Function unknown:Signal transduction mechanisms:PTBA:pyruv_kin:murC:fliN:butyr_kinase:release_prfH:glyc2_xrt_Gpos1:FlgEFG_subfam:Defense mechanisms:Metabolism:Cellular processes and signaling:Information storage and processing:Biosynthesis and degradation of murein sacculus and peptidoglycan:Cell envelope:PTS:Signal transduction:Chemotaxis and motility:Cellular processes:Translation factors:Protein synthesis:Glycolysis/gluconeogenesis:Fermentation:Energy metabolism:Poorly characterized" 360 "Phosphoribosylamine-glycine ligase:Dihydroorotate dehydrogenase:Predicted S-adenosylmethionine-dependent methyltransferase:Orotidine-5'-phosphate decarboxylase:Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase:Uridylate kinase:Aspartate carbamoyltransferase, catalytic chain:Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily):Predicted Zn-dependent peptidases:Predicted transcriptional regulators:Methyl-accepting chemotaxis protein:Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases):Predicted GTPases:Imidazolonepropionase and related amidohydrolases:Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific:Phosphomannose isomerase:Beta-fructosidases (levanase/invertase):Aspartate carbamoyltransferase, regulatory subunit:Zn-dependent proteases:Predicted enzyme related to lactoylglutathione lyase:Nucleotide transport and metabolism:Carbohydrate transport and metabolism:Coenzyme transport and metabolism:Lipid transport and metabolism:Transcription:Cell motility:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:Signal transduction mechanisms:TIGR00091:HMP-P_kinase:asp_carb_tr:EIIB_glc:purD:pyrD_sub1_fam:scrB_fam:pyrH_bact:pyrF_sub2:GTPase_YlqF:Other:Protein synthesis:Pyrimidine ribonucleotide biosynthesis:Purine ribonucleotide biosynthesis:Nucleotide and nucleoside interconversions:Purines, pyrimidines, nucleosides, and nucleotides:Biosynthesis and degradation of polysaccharides:Energy metabolism:Metabolism:Poorly characterized:Cellular processes and signaling:Information storage and processing:PTS:Signal transduction:Thiamine:Biosynthesis of cofactors, prosthetic groups, and carriers:tRNA and rRNA base modification" 361 "Glycosyltransferase:ATP-dependent exoDNAse (exonuclease V), alpha subunit - helicase superfamily I member:Methyl-accepting chemotaxis protein:Hemolysins and related proteins containing CBS domains:Na+/melibiose symporter and related transporters:Predicted membrane protein:Anaerobic C4-dicarboxylate transporter:Predicted enzyme involved in methoxymalonyl-ACP biosynthesis:Uncharacterized conserved protein:Uncharacterized protein conserved in bacteria:Uncharacterized conserved protein:Carbohydrate transport and metabolism:Replication, recombination and repair:Cell wall/membrane/envelope biogenesis:Cell motility:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:Function unknown:Signal transduction mechanisms:Dcu:HAD-SF-IIIC:Metabolism:Cellular processes and signaling:Information storage and processing:Carbohydrates, organic alcohols, and acids:Transport and binding proteins:Poorly characterized" 362 "Ribosomal protein L4:Ribosomal protein S3:Ribosomal protein L14:Ribosomal protein S8:Ribosomal protein S5:Ribosomal protein S11:Ribosomal protein S17:Ribosomal protein L16/L10E:Ribosomal protein S14:Ribosomal protein L18:Ribosomal protein S4 and related proteins:Adenylate kinase and related kinases:Ribosomal protein L30/L7E:Nucleotide transport and metabolism:Translation, ribosomal structure and biogenesis:L18_bact:rpsC_bact:rpsD_bact:rpsE_bact:rpmJ_bact:rplN_bact:rplP_bact:rpmD_bact:adk:bact_S11:S17_bact:rplD_bact:Nucleotide and nucleoside interconversions:Protein synthesis:Ribosomal proteins: synthesis and modification:Information storage and processing:Metabolism:Purines, pyrimidines, nucleosides, and nucleotides" 363 "Energy production and conversion:Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase]:Enolase:Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases:Predicted tRNA(5-methylaminomethyl-2-thiouridylate) methyltransferase, contains the PP-loop ATPase domain:ABC-type sulfate transport system, permease component:Exoribonuclease R:ABC-type molybdate transport system, periplasmic component:Lactate dehydrogenase and related dehydrogenases:Thiamine biosynthesis enzyme ThiH and related uncharacterized enzymes:Oxygen-sensitive ribonucleoside-triphosphate reductase:DNA-binding protein, stimulates sugar fermentation:Ferritin-like protein:Zn-ribbon protein, possibly nucleic acid-binding:Acetyltransferases, including N-acetylases of ribosomal proteins:Arginine/lysine/ornithine decarboxylases:Electron transfer flavoprotein, alpha subunit:Regulator of polyketide synthase expression:Predicted membrane protein:Uncharacterized protein with conserved CXXC pairs:Amino acid transport and metabolism:Nucleotide transport and metabolism:Carbohydrate transport and metabolism:Coenzyme transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:Posttranslational modification, protein turnover, chaperones:Inorganic ion transport and metabolism:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:Function unknown:Signal transduction mechanisms:gatA:sfsA:3_prime_RNase:trmU:eno:modA:Mo_ABC_porter:thiH:thiF_fam2:NrdD:Purines, pyrimidines, nucleosides, and nucleotides:Glycolysis/gluconeogenesis:Energy metabolism:Protein synthesis:Metabolism:Poorly characterized:Information storage and processing:Thiamine:Biosynthesis of cofactors, prosthetic groups, and carriers:Anions:Transport and binding proteins:tRNA and rRNA base modification:tRNA aminoacylation:Cellular processes and signaling:Degradation of RNA:Transcription:Other:Regulatory functions:2'-Deoxyribonucleotide metabolism" 364 "Cation transport ATPase:Predicted xylanase/chitin deacetylase:Uncharacterized conserved protein:Uncharacterized conserved protein:Putative Ser protein kinase:Carbohydrate transport and metabolism:Inorganic ion transport and metabolism:Function unknown:Signal transduction mechanisms:ATPase_P-type:spore_ybaN_pdaB:spore_III_AG:spore_III_AB:spore_III_D:spore_III_AC:spore_yhbH:spore_CotS:Cellular processes and signaling:Cellular processes:Sporulation and germination:Poorly characterized:Metabolism" 365 "Guanosine polyphosphate pyrophosphohydrolases/synthetases:UDP-N-acetylglucosamine 2-epimerase:Glycosyltransferase:ATPases involved in chromosome partitioning:Zn-dependent hydrolases, including glyoxylases:Coproporphyrinogen III oxidase and related Fe-S oxidoreductases:Predicted glycosyltransferases:Transcriptional regulator:D-Tyr-tRNAtyr deacylase:Preprotein translocase subunit YajC:Membrane protein involved in the export of O-antigen and teichoic acid:Capsular polysaccharide biosynthesis protein:Cell cycle control, cell division, chromosome partitioning:Coenzyme transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:Cell wall/membrane/envelope biogenesis:General function prediction only:Signal transduction mechanisms:wecB:TIGR00256:lytR_cpsA_psr:spoT_relA:yajC:eps_fam:rSAM_HemZ:Intracellular trafficking, secretion, and vesicular transport:Cellular processes and signaling:Information storage and processing:Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides:Cell envelope:Heme, porphyrin, and cobalamin:Biosynthesis of cofactors, prosthetic groups, and carriers:Adaptations to atypical conditions:Poorly characterized:Carbohydrates, organic alcohols, and acids:Transport and binding proteins:Protein and peptide secretion and trafficking:Protein fate:tRNA aminoacylation:Protein synthesis:Other:Regulatory functions:Cellular processes:Metabolism" 366 "Cytosine deaminase and related metal-dependent hydrolases:Panthothenate synthetase:ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component:Transcriptional regulator:Integral membrane protein, interacts with FtsH:ABC-type molybdate transport system, periplasmic component:Predicted xylanase/chitin deacetylase:Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain:Aspartate 1-decarboxylase:Uncharacterized conserved protein:Cellulase M and related proteins:N-acetylglucosamine-6-phosphate deacetylase:Phosphotransferase system IIA components:Altronate dehydratase:Alpha-L-arabinofuranosidase:Phage-related holin (Lysis protein):L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily:Amino acid transport and metabolism:Nucleotide transport and metabolism:Carbohydrate transport and metabolism:Coenzyme transport and metabolism:Transcription:Cell wall/membrane/envelope biogenesis:Inorganic ion transport and metabolism:General function prediction only:Signal transduction mechanisms:panC:nagA:panD:PTBA:modA:holin_tox_secr:oligo_HPY:SASP_H:Anions:Amino acids, peptides and amines:Transport and binding proteins:Amino sugars:Central intermediary metabolism:Mobile and extrachromosomal element functions:Metabolism:Poorly characterized:Information storage and processing:PTS:Signal transduction:Pantothenate and coenzyme A:Biosynthesis of cofactors, prosthetic groups, and carriers:Prophage functions:Cellular processes and signaling:Sporulation and germination:Cellular processes" 367 "Nitrogen regulatory protein PII:Acetolactate synthase, small (regulatory) subunit:Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily:DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog:Uncharacterized conserved protein, contains double-stranded beta-helix domain:Zn-dependent proteases:Deoxycytidylate deaminase:FOG: EAL domain:Serine phosphatase RsbU, regulator of sigma subunit:Uncharacterized protein conserved in bacteria:Uncharacterized protein conserved in bacteria:Uncharacterized conserved protein:Amino acid transport and metabolism:Nucleotide transport and metabolism:Transcription:Cell wall/membrane/envelope biogenesis:General function prediction only:Function unknown:Signal transduction mechanisms:acolac_sm:GGDEF:spore_YyaC:spore_II_E:sigma70-ECF:Other:Signal transduction:Pyruvate family:Amino acid biosynthesis:Sporulation and germination:Cellular processes:Metabolism:Poorly characterized:Cellular processes and signaling:Information storage and processing"