MSMEG_2379 MSMEG_2379 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (3-IPM-DH) (Beta-IPM dehydrogenase)
Mycobacterium smegmatis (strain ATCC 700084 / mc(2)155)

Mycobacterium smegmatis (strain ATCC 700084 / mc(2)155)

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Summary

	Locus Tag	Symbol	Synonyms	Product	Protein Synonyms	Start	End	Strand	PubMed ID
MSMEG_2379	MSMEG_2379	leuB	leuB, MSMEG_2379, MSMEI_2319		3-isopropylmalate dehydrogenase (EC 1.1.1.85) (3-IPM-DH) (Beta-IPM dehydrogenase)				17295914, 18955433

Regulatory Modules

	Residual	Motif 1	Expression Plot
msm_bicluster_0054	0.58
msm_bicluster_0567	0.55

XReference

Uniprot	NCBI Gene	NCBI Protein	EnsemblBacteria	InterPro	EggNOG	OrthoDB
A0QUY3	4534280;	WP_011728304.1, YP_886721.1	ABK71356, AFP38789	IPR023698, IPR019818, IPR001804, IPR024084	COG0473, ENOG4105C0C	EOG65N1BN

Mutations

Line	Position	Effect	Impact	Class	Percent Frequency	AA

Transposon mutants

Title	Insert	TAG Module
NA

Homology

Orthologues	Paralogues

Functions

Catalytic Activity	KEGG Ontology	Pathways
(2R,3S)-3-isopropylmalate + NAD(+) = 4-methyl-2-oxopentanoate + CO(2) + NADH, ECO:0000256|HAMAP-Rule:MF_01035}.	msg:MSMEI_2319, msm:MSMEG_2379	Amino-acid biosynthesis, L-leucine biosynthesis, L-leucine from 3-methyl-2-oxobutanoate: step 3/4. {ECO:0000256|HAMAP-Rule:MF_01035}.

Product Synonyms

Product (LegacyBRC)	Product (RefSeq)

Operon

Refseq

GI Number	Accession	Blast	Conserved Domains

GO Terms

GO:0003862 GO:0051287 GO:0005737 GO:0009098 GO:0000287 -

GO:0003862

GO:0051287

GO:0005737

GO:0009098

GO:0000287

String Network

Link to STRINGS	STRINGS Network
MSMEG_2379

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