Module 8 Residual: 0.58Mycobacterium smegmatis (strain ATCC 700084 / mc(2)155)

Summary

Residual	Motif 1 e-value	Motif 2 e-value	Conditions	Genes	version
0.58	0.0000000000038	0.0000000000035	78	35	20160204

Motifs

Motif 1
	e-value: 0.0000000000038
Motif 2
	e-value: 0.0000000000035

Module Plots

Members

MSMEG_6093 Uncharacterized protein	MSMEG_5150 Putative pterin-4-alpha-carbinolamine dehydratase (PHS) (EC 4.2.1.96) (4-alpha-hydroxy-tetrahydropterin dehydratase) (Pterin carbinolamine dehydratase) (PCD)
MSMEG_6091 ATP-dependent Clp protease ATP-binding subunit ClpC1	MSMEG_2593 Gnat-family protein acetyltransferase
MSMEG_0965 Porin MspA	MSMEG_2639 Integral membrane protein
MSMEG_6157 DNA topoisomerase 1 (EC 5.99.1.2) (DNA topoisomerase I)	MSMEG_2804 Two-component system sensor kinase
MSMEG_3525 Transcriptional regulator, XRE family (Transcriptional regulator, XRE family protein)	MSMEG_2806 Two-component system response regulator
MSMEG_1595 Putative oxidoreductase (EC 1.-.-.-) (Short-chain dehydrogenase/reductase SDR) (EC 1.1.1.100)	MSMEG_5881 Carbon monoxide dehydrogenase subunit G (Putative carbon monoxide dehydrogenase subunit G)
MSMEG_4059 Haloacid dehalogenase, type II (EC 3.8.1.2)	MSMEG_5880 Nicotine dehydrogenase (Xanthine dehydrogenase, molybdenum binding subunit apoprotein) (EC 1.17.1.4)
MSMEG_6135 Uncharacterized protein	MSMEG_5883 (2Fe-2S)-binding protein (EC 1.-.-.-) ([2Fe-2S] binding domain protein)
MSMEG_4393 Carboxyvinyl-carboxyphosphonate phosphorylmutase (EC 2.7.8.23) (Putative carboxyvinyl-carboxyphosphonate phosphorylmutase 1 (Carboxyphosphonoenolpyruvate phosphonomutase))	MSMEG_1596 Transcriptional regulator (Transcriptional regulator, TetR family)
MSMEG_2576 Deoxyribodipyrimidine photo-lyase (EC 4.1.99.3)	MSMEG_5882 Aerobic-type carbon monoxide dehydrogenase protein, FAD-binding subunit (Carbon monoxide dehydrogenase medium chain) (EC 1.2.99.2)
MSMEG_2578 1-deoxy-D-xylulose 5-phosphate reductoisomerase (DXP reductoisomerase) (EC 1.1.1.267) (1-deoxyxylulose-5-phosphate reductoisomerase) (2-C-methyl-D-erythritol 4-phosphate synthase)	MSMEG_6935 N-acetylmuramoyl-L-alanine amidase (EC 3.5.1.28)
MSMEG_2579 Zinc metalloprotease Rip1 (EC 3.4.24.-) (Regulator of sigma KLM proteases) (S2P endopeptidase) (Site-2-type intramembrane protease) (site-2 protease Rip1) (S2P protease Rip1)	MSMEG_3487 Metal dependent phosphohydrolase (EC 4.2.1.69) (Metal-dependent phosphohydrolase)
MSMEG_0477 Uncharacterized protein	MSMEG_4594 Uncharacterized protein
MSMEG_5976 Epimerase/dehydratase (NAD dependent epimerase/dehydratase) (EC 5.1.3.2)	MSMEG_4195 Uncharacterized protein
MSMEG_5879 D-alanyl-D-alanine dipeptidase (D-Ala-D-Ala dipeptidase) (EC 3.4.13.22)	MSMEG_4196 Lipoprotein lppL (LppL protein)
MSMEG_6197 Diaminopimelate decarboxylase (EC 4.1.1.20)	MSMEG_1315 Transporter, small conductance mechanosensitive ion channel (MscS) family protein
MSMEG_3133 Uncharacterized protein	MSMEG_3488 Transcriptional regulator, AraC family protein
MSMEG_3940 Universal stress protein family protein (UspA)

Conditions

KO_stationary.phase_rep1

KO_stationary.phase_rep2

WT.vs..DamtR.without.N_rep1

Stationary.cultures.induced.to.express.I.SceI.for.45.minutes..T.45...ATc.

dcpA.knockout.rep2

M..smegmatis.Acid.NO.treated

Biological.replicate.4.of.6..negative.control

dosR.WT_Replicate4

Biological.replicate.4.of.7..ethambutol.treatment

Bedaquiline.vs..DMSO.30min

Biological.replicate.2.of.7..falcarinol.treatment

dosR.WT_Replicate3

KO_log.phase_rep2

KO_log.phase_rep1

Biological.replicate.7.of.7..falcarinol.treatment

Wild.type.rep1.y

MB100pruR.vs..MB100.rep.2

WT.vs..DamtR.without.N_.dyeswap_rep1

WT.vs..DamtR.without.N_.dyeswap_rep2

Biological.replicate.1.of.6..isoniazid.treatment

Biological.replicate.7.of.7..ethambutol.treatment

Biological.replicate.1.of.7..ethambutol.treatment

Biological.replicate.3.of.7..ethambutol.treatment

rel.knockout.rep1

Biological.replicate.1.of.7..falcarinol.treatment

Biological.replicate.6.of.7..falcarinol.treatment

Bedaquiline.vs..DMSO.15min

DamtR.with.vs..DamtR.without.N_.rep1

JR121..pJR29.VapC..vs..JR121..pJR230..VapBC..rep3

Biological.replicate.3.of.6..isoniazid.treatment

DamtR.with.vs..DamtR.without.N_.rep2

WT_log.phase_rep2

X0.6..vs..50..air.saturation.Replicate.3

X0.6..vs..50..air.saturation.Replicate.2

X0.6..vs..50..air.saturation.Replicate.5

Biological.replicate.6.of.7..ethambutol.treatment

M.smegmatis_mc2_155_dMSMEG_0166_study_mutant_rep3

stphcy5plogcy3slide487norm

Biological.replicate.1.of.7..panaxydol.treatment

Biological.replicate.3.of.6..negative.control

Biological.replicate.5.of.7..panaxydol.treatment

X4dbfcy5plogcy3slide480norm

WT.vs..DamtR.N.surplus_rep1

Plogcy5plogcy3slide111norm

stphcy5plogcy3slide580norm

X2.5..vs..50..air.saturation.Replicate.4

Stationary.phase.cultures.induced.to.express.I.SceI.for.15.minutes..T.15...ATc.

stphcy3plogcy5slide581norm

Biological.replicate.4.of.7..panaxydol.treatment

X3dbfcy5plogcy3slide603norm

DamtR.with.vs..DamtR.without.N_dyeswap_.rep1

Biological.replicate.2.of.7..panaxydol.treatment

X4XR.rep2

X4XR.rep1

Wild.type.rep2.x

Slow.vs..Fast.Replicate.5

Slow.vs..Fast.Replicate.1

Slow.vs..Fast.Replicate.2

Biological.replicate.5.of.6..negative.control

mc2155.pMind..vs.mc2155.pMind.6189.replicate.4

BatchCulture_LBTbroth_ExponentialPhase_Replicate1

mc2155.pMind..vs.mc2155.pMind.6189.replicate.2

BatchCulture_LBTbroth_ExponentialPhase_Replicate4

X4dbfcy5plogcy3slide901norm

WT.vs..DamtR.N.surplus_dyeswap_rep2

Log.phase.cultures.without.induction.of.I.SceI.expression..T.0...Atc.

WT.vs..DglnR.N_starvation_dye.swap_rep2

JR121..pJR29.VapC..vs..JR121..pJR230..VapBC..rep1

BatchCulture_LBTbroth_StationaryPhase_Replicate4

JR121..pJR29.VapC..vs..JR121..pJR230..VapBC..rep2

Plogcy5plogcy3slide113norm

JR121..pJR29.VapC..vs..JR121..pJR230..VapBC..rep4

M.smegmatis_mc2_155_dMSMEG_0166_study_wild.type_rep3

Biological.replicate.4.of.6..isoniazid.treatment

X4dbfcy3plogcy5slide903norm

Biological.replicate.6.of.7..panaxydol.treatment

Wild.type.rep3

Bedaquiline.vs..DMSO.120min

Comments