Module 135 Residual: 0.57Mycobacterium smegmatis (strain ATCC 700084 / mc(2)155)

Summary

Residual	Motif 1 e-value	Motif 2 e-value	Conditions	Genes	version
0.57	2.5e-18	0.00013	82	27	20160204

Motifs

Motif 1
	e-value: 2.5e-18
Motif 2
	e-value: 0.00013

Module Plots

Members

MSMEG_6711 4-hydroxybenzoate transporter (General substrate transporter:Major facilitator superfamily MFS_1)	MSMEG_0136 MCE-family protein MCE1c (Virulence factor Mce family protein, putative)
MSMEG_6869 Regulatory protein	MSMEG_0137 MCE-family protein MCE1d (Virulence factor mce family protein)
MSMEG_3178 DNA-directed DNA polymerase (EC 2.7.7.7)	MSMEG_2734 tRNA dimethylallyltransferase (EC 2.5.1.75) (Dimethylallyl diphosphate:tRNA dimethylallyltransferase) (DMAPP:tRNA dimethylallyltransferase) (DMATase) (Isopentenyl-diphosphate:tRNA isopentenyltransferase) (IPP transferase) (IPPT) (IPTase)
MSMEG_0419 Integral membrane protein (Succinate dehydrogenase (Membrane anchor subunit))	MSMEG_0135 MCE-family protein MCE1b (Virulence factor Mce family protein)
MSMEG_0418 Succinate dehydrogenase flavoprotein subunit (EC 1.3.99.1) (Succinate dehydrogenase subunit A) (EC 1.3.-.-)	MSMEG_6871 Isomerase (Mandelate racemase/muconate lactonizing enzyme) (EC 4.2.1.40)
MSMEG_0417 Putative succinate dehydrogenase iron-sulfur subunit (EC 1.3.-.-) (Succinate dehydrogenase)	MSMEG_6870 Creatinine amidohydrolase (Putative creatinine amidohydrolase (Creatininase)) (EC 3.5.2.10)
MSMEG_5798 Phosphoribosylformylglycinamidine cyclo-ligase (EC 6.3.3.1) (AIR synthase) (AIRS) (Phosphoribosyl-aminoimidazole synthetase)	MSMEG_0133 ABC-transporter integral membrane protein (Conserved hypothetical integral membrane protein Yrbe1b)
MSMEG_0138 Virulence factor Mce family protein	MSMEG_3808 UvrABC system protein A (UvrA protein) (Excinuclease ABC subunit A)
MSMEG_0139 MCE-family protein MCE1f (Mce-family protein mce1f)	MSMEG_0134 MCE-family protein MCE1a (Virulence factor Mce family protein)
MSMEG_1261 Uncharacterized protein	MSMEG_5004 DNA repair exonuclease (DNA repair exonuclease SbcD)
MSMEG_1260 Uncharacterized protein	MSMEG_5006 Phosphohistidine phosphatase
MSMEG_2732 Uncharacterized protein	MSMEG_3810 Hydrolase
MSMEG_2733 Uncharacterized protein	MSMEG_5002 Conserved hydrolase (Uncharacterized protein)
MSMEG_2731 Uncharacterized protein MSMEG_2731/MSMEI_2664

Conditions

KO_stationary.phase_rep1

KO_stationary.phase_rep2

WT.vs..DglnR.N_starvation_rep2

Wild.type.rep2.y

WT.vs..DamtR.without.N_rep2

Wild.type.rep2.x

Biological.replicate.4.of.7..ethambutol.treatment

MB100pruR.vs..MB100..rep.3

dosR.WT_Replicate2

KO_log.phase_rep1

Biological.replicate.7.of.7..falcarinol.treatment

Wild.type.rep1.x

Wild.type.rep1.y

MB100pruR.vs..MB100.rep.4

Biological.replicate.3.of.7..panaxydol.treatment

Biological.replicate.6.of.6..negative.control

DglnR_without.vs..with.N_rep2

Biological.replicate.1.of.6..kanamycin.treatment

Biological.replicate.1.of.6..isoniazid.treatment

Biological.replicate.1.of.7..ethambutol.treatment

rel.knockout.rep2

Biological.replicate.1.of.7..falcarinol.treatment

Biological.replicate.3.of.7..falcarinol.treatment

Biological.replicate.6.of.7..falcarinol.treatment

Bedaquiline.vs..DMSO.15min

DamtR.with.vs..DamtR.without.N_.rep1

Biological.replicate.3.of.7..ethambutol.treatment

Biological.replicate.3.of.6..isoniazid.treatment

DamtR.with.vs..DamtR.without.N_.rep2

WT_log.phase_rep2

X0.6..vs..50..air.saturation.Replicate.3

DglnR_without.vs..with.N_rep1

Biological.replicate.5.of.7..falcarinol.treatment

X0.6..vs..50..air.saturation.Replicate.4

M.smegmatis_mc2_155_dMSMEG_0166_study_mutant_rep3

M.smegmatis_mc2_155_dMSMEG_0166_study_mutant_rep2

stphcy5plogcy3slide487norm

mc2155.vs.Dcrp1.replicate.1

Biological.replicate.2.of.7..ethambutol.treatment

Biological.replicate.3.of.6..negative.control

Biological.replicate.5.of.7..panaxydol.treatment

dcpA.knockout.rep1

Sub.MIC.INH

WT.vs..DamtR.N.surplus_rep1

Plogcy5plogcy3slide111norm

stphcy5plogcy3slide580norm

X2.5..vs..50..air.saturation.Replicate.4

WT.with.vs..without.N_dye.swap_rep1

stphcy3plogcy5slide581norm

Biological.replicate.4.of.7..panaxydol.treatment

mc2155.pMind..vs.mc2155.pMind.6189.replicate.4

X2.5..vs..50..air.saturation.Replicate.2

WT.with.vs..without.N_dye.swap_rep2

WT_stationary.phase_rep2

WT_stationary.phase_rep1

X4XR.rep2

DamtR.with.vs..DamtR.without.N_dyeswap_.rep1

Biological.replicate.5.of.7..ethambutol.treatment

Bedaquiline.vs..DMSO.60min

Biological.replicate.4.of.7..falcarinol.treatment

Biological.replicate.6.of.7..ethambutol.treatment

Biological.replicate.7.of.7..panaxydol.treatment

X3dbfcy5plogcy3slide603norm

mc2155.pMind..vs.mc2155.pMind.6189.replicate.3

X4dbfcy5plogcy3slide901norm

WT.vs..DamtR.N.surplus_.dyeswap_rep1

WT.with.vs..without.N_rep2

WT.with.vs..without.N_rep1

DglnR_without.vs..with.N_dyeswap_rep2

Log.phase.cultures.induced.to.express.I.SceI.for.45.minutes..T.45...ATc.

X2XR.rep2

DglnR_without.vs..with.N_dyeswap_rep1

WT.vs..DglnR.N_starvation_dye.swap_rep2

Biological.replicate.2.of.6..negative.control

JR121..pJR29.VapC..vs..JR121..pJR230..VapBC..rep3

JR121..pJR29.VapC..vs..JR121..pJR230..VapBC..rep2

BatchCulture_LBTbroth_StationaryPhase_Replicate1

M.smegmatis_mc2_155_dMSMEG_0166_study_wild.type_rep3

Stationary.phase.cultures.induced.to.express.I.SceI.for.15.minutes..T.15...ATc.

X4dbfcy3plogcy5slide903norm

Biological.replicate.6.of.7..panaxydol.treatment

Bedaquiline.vs..DMSO.120min

Comments