Module 245 Residual: 0.58Mycobacterium smegmatis (strain ATCC 700084 / mc(2)155)

Summary

Residual	Motif 1 e-value	Motif 2 e-value	Conditions	Genes	version
0.58	2.2e-22	3e-22	75	34	20160204

Motifs

Motif 1
	e-value: 2.2e-22
Motif 2
	e-value: 3e-22

Module Plots

Members

MSMEG_1999 Uncharacterized protein	MSMEG_6644 Citrate (Pro-3S)-lyase (EC 4.1.3.-) (Malyl-CoA lyase)
MSMEG_6488 Uncharacterized protein	MSMEG_2209 Transcriptional regulator, GntR family (Transcriptional regulator, GntR family protein)
MSMEG_6505 Nitroreductase NfnB (NR NfnB) (EC 1.-.-.-) (FMN-dependent NAD(P)H nitroreductase)	MSMEG_2206 3-oxoacyl-(Acyl-carrier-protein) reductase (EC 1.1.1.100)
MSMEG_6503 Transcriptional regulator, TetR family (Transcriptional regulator, TetR family protein)	MSMEG_2207 Beta-ketothiolase
MSMEG_2245 Bile-acid 7-alpha dehydratase (EC 4.2.1.106) (Uncharacterized protein)	MSMEG_2205 Putative acyl-CoA dehydrogenase
MSMEG_0985 Dicarboxylic acid transport integral membrane protein KgtP (Sugar transporter family protein)	MSMEG_5966 Oxidoreductase, short chain dehydrogenase/reductase family protein (Short-chain dehydrogenase/reductase SDR) (EC 1.1.1.100)
MSMEG_6335 Uncharacterized protein	MSMEG_6549 Uncharacterized protein
MSMEG_2909 Mandelate racemase/muconate lactonizing enzyme (Starvation-sensing protein RspA)	MSMEG_3992 Integral membrane transport protein (Metabolite transporter, MFS superfamily protein)
MSMEG_1204 3-oxoacyl-(Acyl-carrier-protein) synthase 2 KasB (EC 2.3.1.41) (3-oxoacyl-[acyl-carrier-protein] synthase 2)	MSMEG_5801 Hydroxylase (Uncharacterized protein)
MSMEG_6620 Uncharacterized protein	MSMEG_0999 Conserved integral membrane protein (Integral membrane protein)
MSMEG_4223 Uncharacterized protein	MSMEG_2244 Rieske (2Fe-2S) region (Rieske [2Fe-2S] domain protein)
MSMEG_4556 GTP-binding protein LepA	MSMEG_5802 Oxidoreductase, short chain dehydrogenase/reductase family protein (Short-chain dehydrogenase/reductase SDR) (EC 1.1.1.100)
MSMEG_4442 Alcohol dehydrogenase, zinc-binding protein (EC 1.6.5.5) (Zinc-binding oxidoreductase)	MSMEG_5905 Uncharacterized protein
MSMEG_5522 TetR-family transcriptional regulator (Transcriptional Regulator, TetR family protein)	MSMEG_4988 Integral membrane protein
MSMEG_5521 Acetyl-CoA acetyltransferase	MSMEG_0896 Integral membrane transport protein (Major facilitator superfamily MFS_1)
MSMEG_2789 Acetyltransferase, GNAT family protein (GCN5-related N-acetyltransferase)	MSMEG_1151 DNA-binding protein (Transcriptional regulator, XRE family with cupin sensor)
MSMEG_3361 Uncharacterized protein	MSMEG_2208 Acyl-CoA dehydrogenase (EC 1.3.8.1) (EC 1.3.99.-)

Conditions

WT.vs..DglnR.N_starvation_rep2

Biological.replicate.2.of.7..panaxydol.treatment

Stationary.phase.cultures.induced.to.express.I.SceI.for.15.minutes..T.15...ATc.

WT.vs..DamtR.without.N_rep2

Mycobacterium.smegmatis.Spheroplast.induced

Wild.type.rep2.x

Biological.replicate.1.of.6..negative.control

dosR.WT_Replicate3

Biological.replicate.5.of.6..negative.control

KO_log.phase_rep2

KO_log.phase_rep1

DglnR_without.vs..with.N_rep1

Wild.type.rep1.x

Wild.type.rep1.y

DglnR_without.vs..with.N_rep2

Biological.replicate.1.of.6..kanamycin.treatment

Biological.replicate.1.of.6..isoniazid.treatment

Biological.replicate.7.of.7..ethambutol.treatment

mc2155.pMind..vs.mc2155.pMind.6189.replicate.1

Biological.replicate.6.of.6..kanamycin.treatment

Biological.replicate.3.of.7..falcarinol.treatment

Wild.type.rep3

Bedaquiline.vs..DMSO..45min

Biological.replicate.6.of.7..falcarinol.treatment

Bedaquiline.vs..DMSO.15min

DamtR.with.vs..DamtR.without.N_.rep1

Biological.replicate.4.of.6..isoniazid.treatment

DamtR.with.vs..DamtR.without.N_.rep2

X0.6..vs..50..air.saturation.Replicate.2

X0.6..vs..50..air.saturation.Replicate.5

WT.vs..DamtR.N.surplus_rep2

M.smegmatis_mc2_155_dMSMEG_0166_study_mutant_rep2

mc2155.vs.Dcrp1.replicate.2

M.smegmatis_mc2_155_dMSMEG_0166_study_mutant_rep1

mc2155.vs.Dcrp1.replicate.1

Biological.replicate.1.of.7..panaxydol.treatment

Biological.replicate.3.of.6..negative.control

Biological.replicate.5.of.7..panaxydol.treatment

dcpA.knockout.rep1

Biological.replicate.2.of.6..isoniazid.treatment

stphcy5plogcy3slide580norm

X3dbfcy5plogcy3slide601norm

WT.with.vs..without.N_dye.swap_rep1

stphcy3plogcy5slide581norm

Biological.replicate.4.of.7..panaxydol.treatment

X2.5..vs..50..air.saturation.Replicate.1

X2.5..vs..50..air.saturation.Replicate.2

X2.5..vs..50..air.saturation.Replicate.3

WT_stationary.phase_rep2

Log.phase.cultures.induced.to.express.I.SceI.for.45.minutes..T.45...ATc.

Biological.replicate.6.of.6..isoniazid.treatment

DamtR.with.vs..DamtR.without.N_dyeswap_.rep1

mc2155.vs.Dcrp1.replicate.3

Tet.CarD.vs.Control..Replicates.1..2..and.3.

Bedaquiline.vs..DMSO.60min

WT.vs..DglnR.N_starvation_dye.swap_rep1

WT.vs..DglnR.N_starvation_dye.swap_rep2

Biological.replicate.7.of.7..panaxydol.treatment

BatchCulture_LBTbroth_ExponentialPhase_Replicate3

X3dbfcy5plogcy3slide603norm

BatchCulture_LBTbroth_ExponentialPhase_Replicate4

WT.vs..DamtR.N.surplus_.dyeswap_rep1

WT.with.vs..without.N_rep2

WT.with.vs..without.N_rep1

DglnR_without.vs..with.N_dyeswap_rep2

X2XR.rep1

DglnR_without.vs..with.N_dyeswap_rep1

WT.vs..DglnR.N_starvation_rep1

BatchCulture_LBTbroth_StationaryPhase_Replicate4

JR121..pJR29.VapC..vs..JR121..pJR230..VapBC..rep2

Biological.replicate.4.of.6..negative.control

BatchCulture_LBTbroth_StationaryPhase_Replicate1

M.smegmatis_mc2_155_dMSMEG_0166_study_wild.type_rep1

X4dbfcy3plogcy5slide903norm

Biological.replicate.6.of.7..panaxydol.treatment

Comments