Module 529 Residual: 0.51Mycobacterium smegmatis (strain ATCC 700084 / mc(2)155)

Summary

Residual	Motif 1 e-value	Motif 2 e-value	Conditions	Genes	version
0.51	6e-16	0.0000000000022	77	26	20160204

Motifs

Motif 1
	e-value: 6e-16
Motif 2
	e-value: 0.0000000000022

Module Plots

Members

MSMEG_4231 UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase (EC 6.3.2.10)	MSMEG_3807 TetR-type regulator
MSMEG_4230 Phospho-N-acetylmuramoyl-pentapeptide-transferase (EC 2.7.8.13) (UDP-MurNAc-pentapeptide phosphotransferase)	MSMEG_3805 Oxidoreductase, short chain dehydrogenase/reductase family protein
MSMEG_4233 Penicillin-binding protein PbpB (EC 2.4.1.129) (PBP3)	MSMEG_0014 Methionyl-tRNA formyltransferase (EC 2.1.2.9)
MSMEG_4232 UDP-N-acetylmuramyl-tripeptide synthetase (EC 6.3.2.-)	MSMEG_0016 Conserved domain protein
MSMEG_4235 Ribosomal RNA small subunit methyltransferase H (EC 2.1.1.199) (16S rRNA m(4)C1402 methyltransferase) (rRNA (cytosine-N(4)-)-methyltransferase RsmH)	MSMEG_4226 UDP-N-acetylmuramate--L-alanine ligase (EC 6.3.2.8) (UDP-N-acetylmuramoyl-L-alanine synthetase)
MSMEG_4234 FHA domain containing protein (Uncharacterized protein)	MSMEG_4227 UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase (EC 2.4.1.227) (Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase)
MSMEG_5657 Transcriptional regulator, LysR family (Transcriptional regulator, LysR family protein)	MSMEG_4225 Cell division protein FtsQ
MSMEG_5658 Epoxide hydrolase (EC 3.3.2.9)	MSMEG_4228 Cell division protein FtsW
MSMEG_3685 Uncharacterized protein	MSMEG_4229 UDP-N-acetylmuramoylalanine--D-glutamate ligase (EC 6.3.2.9) (D-glutamic acid-adding enzyme) (UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase)
MSMEG_3684 Nuclear transport factor 2 (NTF2) domain family protein	MSMEG_0815 Transcriptional regulator, TetR family protein
MSMEG_6634 Triphosphoribosyl-dephospho-CoA synthase (Triphosphoribosyl-dephospho-CoA synthase MdcB) (EC 2.4.2.52)	MSMEG_0712 Transcriptional regulator, TetR family (Transcriptional regulator, TetR family protein)
MSMEG_4422 Oxidoreductase	MSMEG_3872 Precorrin-8X methylmutase (EC 5.4.1.2)
MSMEG_4423 Alcohol dehydrogenase, zinc-binding protein (EC 1.6.5.5) (Oxidoreductase)	MSMEG_3873 Cobalamin biosynthesis protein cobIJ (EC 2.1.1.130) (Precorrin-3B C17-methyltransferase) (EC 2.1.1.131)

Conditions

KO_stationary.phase_rep1

KO_stationary.phase_rep2

WT.vs..DglnR.N_starvation_rep2

Stationary.cultures.induced.to.express.I.SceI.for.45.minutes..T.45...ATc.

WT.vs..DamtR.without.N_rep2

Biological.replicate.4.of.6..negative.control

Wild.type.rep2.x

Biological.replicate.5.of.6..isoniazid.treatment

MB100pruR.vs..MB100..rep.3

dosR.WT_Replicate2

KO_log.phase_rep2

KO_log.phase_rep1

Biological.replicate.7.of.7..falcarinol.treatment

Wild.type.rep1.y

MB100pruR.vs..MB100.rep.4

Biological.replicate.6.of.6..negative.control

WT.vs..DamtR.without.N_.dyeswap_rep1

Biological.replicate.2.of.7..panaxydol.treatment

Biological.replicate.1.of.6..isoniazid.treatment

Biological.replicate.7.of.7..ethambutol.treatment

Biological.replicate.1.of.7..ethambutol.treatment

Biological.replicate.6.of.6..kanamycin.treatment

rel.knockout.rep2

Bedaquiline.vs..DMSO..45min

Biological.replicate.3.of.7..falcarinol.treatment

DamtR.with.vs..DamtR.without.N_.rep1

Biological.replicate.4.of.6..isoniazid.treatment

Biological.replicate.3.of.6..isoniazid.treatment

DamtR.with.vs..DamtR.without.N_.rep2

X0.6..vs..50..air.saturation.Replicate.1

WT_log.phase_rep2

mc2155.pMind..vs.mc2155.pMind.6189.replicate.4

Biological.replicate.6.of.7..ethambutol.treatment

M.smegmatis_mc2_155_dMSMEG_0166_study_mutant_rep3

M.smegmatis_mc2_155_dMSMEG_0166_study_mutant_rep2

mc2155.vs.Dcrp1.replicate.2

mc2155.vs.Dcrp1.replicate.3

mc2155.vs.Dcrp1.replicate.1

mc2155.vs.Dcrp1.replicate.4

X0.6..vs..50..air.saturation.Replicate.4

Biological.replicate.5.of.7..panaxydol.treatment

dcpA.knockout.rep1

X4dbfcy5plogcy3slide480norm

WT.vs..DamtR.N.surplus_rep1

X3dbfcy5plogcy3slide601norm

Stationary.phase.cultures.induced.to.express.I.SceI.for.15.minutes..T.15...ATc.

Biological.replicate.2.of.7..ethambutol.treatment

WT_log.phase_rep1

WT.with.vs..without.N_dye.swap_rep1

X2.5..vs..50..air.saturation.Replicate.1

WT.with.vs..without.N_dye.swap_rep2

WT_stationary.phase_rep1

Biological.replicate.6.of.6..isoniazid.treatment

Biological.replicate.5.of.7..ethambutol.treatment

Tet.CarD.vs.Control..Replicates.1..2..and.3.

Stationary.cultures.control.without.induction.of.I.SceI.expression..T.0...Atc.

Bedaquiline.vs..DMSO.60min

Biological.replicate.4.of.7..falcarinol.treatment

Slow.vs..Fast.Replicate.1

Slow.vs..Fast.Replicate.2

Biological.replicate.7.of.7..panaxydol.treatment

dosR.WT_Replicate3

X3dbfcy5plogcy3slide603norm

mc2155.pMind..vs.mc2155.pMind.6189.replicate.3

BatchCulture_LBTbroth_ExponentialPhase_Replicate4

WT.with.vs..without.N_rep2

WT.with.vs..without.N_rep1

DglnR_without.vs..with.N_dyeswap_rep1

WT.vs..DglnR.N_starvation_dye.swap_rep2

WT.vs..DglnR.N_starvation_rep1

BatchCulture_LBTbroth_StationaryPhase_Replicate4

Sub.MIC.INH

Biological.replicate.2.of.6..negative.control

M.smegmatis_mc2_155_dMSMEG_0166_study_wild.type_rep1

Biological.replicate.3.of.6..negative.control

X4dbfcy3plogcy5slide903norm

WT.vs..DglnR.N_starvation_dye.swap_rep1

Comments