Module 672 Residual: 0.56Mycobacterium smegmatis (strain ATCC 700084 / mc(2)155)

Summary

Residual	Motif 1 e-value	Motif 2 e-value	Conditions	Genes	version
0.56	3e-16	0.000097	76	30	20160204

Motifs

Motif 1
	e-value: 3e-16
Motif 2
	e-value: 0.000097

Module Plots

Members

MSMEG_5041 Acyltransferase 3 (Probable acyltransferase)	MSMEG_1207 Glycosyl transferase group 1 (Glycosyltransferase, group I)
MSMEG_5122 4Fe-4S ferredoxin, iron-sulfur binding protein (Ferredoxin)	MSMEG_1888 Putative S-adenosyl-L-methionine-dependent methyltransferase MSMEG_1888/MSMEI_1848 (EC 2.1.1.-)
MSMEG_5043 LprE protein	MSMEG_1128 Uncharacterized protein
MSMEG_5042 ATP-dependent RNA helicase DeaD (EC 3.6.4.13) (Cold-shock DEAD box protein A)	MSMEG_1129 D-amino acid dehydrogenase (EC 1.4.99.1) (D-amino-acid dehydrogenase)
MSMEG_4236 Transcriptional regulator MraZ	MSMEG_6382 FAD-dependent decaprenylphosphoryl-beta-D-ribofuranose 2-oxidase (EC 1.1.98.3) (Decaprenylphospho-beta-D-ribofuranose 2-dehydrogenase) (Decaprenylphosphoryl-beta-D-ribofuranose 2'-epimerase 1) (DprE1)
MSMEG_4627 Nucleoside diphosphate kinase (NDK) (NDP kinase) (EC 2.7.4.6) (Nucleoside-2-P kinase)	MSMEG_4671 ATP-dependent Clp protease ATP-binding subunit ClpX
MSMEG_5730 Permease for cytosine/purines uracil thiamine allantoin (Permease for cytosine/purines, uracil, thiamine, allantoin transporter)	MSMEG_5191 Carbonic anhydrase/acetyltransferase isoleucine patch superfamily-like protein (Siderophore binding protein)
MSMEG_5121 Aminotransferase, classes I and II (N-succinyldiaminopimelate aminotransferase) (EC 2.6.1.-)	MSMEG_5729 Asp/Glu/hydantoin racemase (Hydantoin racemase) (EC 5.1.99.-)
MSMEG_0821 Glutamyl-tRNA(Gln) amidotransferase subunit A (EC 6.3.5.-)	MSMEG_0301 Oxidoreductase, FAD-binding (Putative glycolate oxidase FAD-linked subunit) (EC 1.1.2.4)
MSMEG_1559 Phosphoglucosamine mutase (EC 5.4.2.10)	MSMEG_0303 Alcohol dehydrogenase, zinc-containing
MSMEG_3398 Integral membrane transport protein (Major facilitator superfamily MFS_1)	MSMEG_1504 Antibiotic-transport integral membrane leucine, alanine and valine rich protein ABC transporter (Probable antibiotic-transport integral membrane leucine and alanine and valine rich protein abc transporter)
MSMEG_4682 Na+/H+ antiporter	MSMEG_0205 Antibiotic biosynthesis monooxygenase (Tetracenomycin polyketide synthesis hydroxylase TcmH) (EC 1.-.-.-)
MSMEG_4998 Hydrolase, alpha/beta fold family protein	MSMEG_1502 ABC transporter, ATP-binding protein
MSMEG_5770 Uncharacterized protein	MSMEG_1503 Probable antibiotic-transport integral membrane leucine and valine rich protein abc transporter (Putative antibiotic-transport integral membrane leucine and valine rich protein ABC transporter)
MSMEG_1264 Prophage Lp1 protein 5	MSMEG_1792 Uncharacterized protein

Conditions

Bedaquiline.vs..DMSO.30min

Biological.replicate.5.of.7..falcarinol.treatment

KO_log.phase_rep1

Biological.replicate.5.of.7..panaxydol.treatment

dosR.WT_Replicate4

Biological.replicate.3.of.7..falcarinol.treatment

Biological.replicate.1.of.6..negative.control

MB100pruR.vs..MB100..rep.3

Wild.type.rep2.y

Biological.replicate.7.of.7..falcarinol.treatment

Wild.type.rep1.x

Wild.type.rep1.y

Biological.replicate.4.of.7..ethambutol.treatment

Biological.replicate.3.of.7..panaxydol.treatment

Biological.replicate.6.of.6..negative.control

WT.vs..DamtR.without.N_.dyeswap_rep1

Biological.replicate.1.of.6..kanamycin.treatment

Biological.replicate.7.of.7..ethambutol.treatment

mc2155.pMind..vs.mc2155.pMind.6189.replicate.1

Biological.replicate.1.of.7..ethambutol.treatment

Biological.replicate.2.of.7..falcarinol.treatment

rel.knockout.rep1

MB100pruR.vs..MB100.rep.2

Biological.replicate.6.of.7..falcarinol.treatment

WT.vs..DglnR.N_starvation_dye.swap_rep2

Biological.replicate.4.of.6..isoniazid.treatment

WT.vs..DglnR.N_starvation_dye.swap_rep1

X0.6..vs..50..air.saturation.Replicate.1

X0.6..vs..50..air.saturation.Replicate.3

X0.6..vs..50..air.saturation.Replicate.2

X0.6..vs..50..air.saturation.Replicate.5

X0.6..vs..50..air.saturation.Replicate.4

M.smegmatis_mc2_155_dMSMEG_0166_study_mutant_rep3

M.smegmatis_mc2_155_dMSMEG_0166_study_mutant_rep2

mc2155.vs.Dcrp1.replicate.2

M.smegmatis_mc2_155_dMSMEG_0166_study_mutant_rep1

mc2155.vs.Dcrp1.replicate.1

dcpA.knockout.rep2

dcpA.knockout.rep1

Sub.MIC.INH

WT.vs..DamtR.N.surplus_rep1

Biological.replicate.2.of.6..isoniazid.treatment

X2.5..vs..50..air.saturation.Replicate.4

X2.5..vs..50..air.saturation.Replicate.5

X3dbfcy5plogcy3slide603norm

DamtR.with.vs..DamtR.without.N_dyeswap_.rep1

Biological.replicate.2.of.6..kanamycin.treatment

Log.phase.cultures.induced.to.express.I.SceI.for.45.minutes..T.45...ATc.

Biological.replicate.6.of.6..isoniazid.treatment

mc2155.vs.Dcrp1.replicate.3

Tet.CarD.vs.Control..Replicates.1..2..and.3.

Bedaquiline.vs..DMSO.60min

Biological.replicate.5.of.6..isoniazid.treatment

Slow.vs..Fast.Replicate.1

Slow.vs..Fast.Replicate.2

Biological.replicate.7.of.7..panaxydol.treatment

dosR.WT_Replicate3

mc2155.pMind..vs.mc2155.pMind.6189.replicate.4

BatchCulture_LBTbroth_ExponentialPhase_Replicate1

mc2155.pMind..vs.mc2155.pMind.6189.replicate.2

BatchCulture_LBTbroth_ExponentialPhase_Replicate4

WT.vs..DamtR.N.surplus_.dyeswap_rep1

Log.phase.cultures.without.induction.of.I.SceI.expression..T.0...Atc.

WT.vs..DglnR.N_starvation_rep2

X2XR.rep1

X2XR.rep2

DglnR_without.vs..with.N_dyeswap_rep1

JR121..pJR29.VapC..vs..JR121..pJR230..VapBC..rep1

Stationary.cultures.induced.to.express.I.SceI.for.45.minutes..T.45...ATc.

JR121..pJR29.VapC..vs..JR121..pJR230..VapBC..rep2

BatchCulture_LBTbroth_StationaryPhase_Replicate3

M.smegmatis_mc2_155_dMSMEG_0166_study_wild.type_rep3

M.smegmatis_mc2_155_dMSMEG_0166_study_wild.type_rep2

X4dbfcy3plogcy5slide903norm

Biological.replicate.6.of.7..panaxydol.treatment

Bedaquiline.vs..DMSO.120min

Comments