MSMEG_2374 MSMEG_2374 Ketol-acid reductoisomerase (EC 1.1.1.86) (Acetohydroxy-acid isomeroreductase) (Alpha-keto-beta-hydroxylacyl reductoisomerase)
Mycobacterium smegmatis (strain ATCC 700084 / mc(2)155)

Mycobacterium smegmatis (strain ATCC 700084 / mc(2)155)

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Summary
Locus Tag Symbol Synonyms Product Protein Synonyms Start End Strand PubMed ID
MSMEG_2374 MSMEG_2374 ilvC ilvC, MSMEG_2374, MSMEI_2314 Ketol-acid reductoisomerase (EC 1.1.1.86) (Acetohydroxy-acid isomeroreductase) (Alpha-keto-beta-hydroxylacyl reductoisomerase) 17295914, 18955433
Regulatory Modules
Residual Expression Plot
msm_bicluster_0096 0.52
msm_bicluster_0252 0.55
XReference
Uniprot NCBI Gene NCBI Protein EnsemblBacteria InterPro EggNOG OrthoDB
A0QUX8 4533720; WP_003893742.1, YP_886716.1 ABK74365, AFP38784 IPR008927, IPR013328, IPR000506, IPR013116, IPR013023, IPR016040 ENOG4105C6M, COG0059 EOG625K07
Mutations
Transposon mutants
Title Insert TAG Module
NA
Homology
Orthologues Paralogues
Functions
Catalytic Activity KEGG Ontology Pathways
(2R)-2,3-dihydroxy-3-methylbutanoate + NADP(+) = (2S)-2-hydroxy-2-methyl-3-oxobutanoate + NADPH, ECO:0000255|HAMAP-Rule:MF_00435}.; (2R,3R)-2,3-dihydroxy-3-methylpentanoate + NADP(+) = (S)-2-hydroxy-2-ethyl-3-oxobutanoate + NADPH, ECO:0000255|HAMAP-Rule:MF_00435}. msb:LJ00_11805, msg:MSMEI_2314, msm:MSMEG_2374 Amino-acid biosynthesis, L-isoleucine biosynthesis, L-isoleucine from 2-oxobutanoate: step 2/4. {ECO:0000255|HAMAP-Rule:MF_00435}., Amino-acid biosynthesis, L-valine biosynthesis, L-valine from pyruvate: step 2/4. {ECO:0000255|HAMAP-Rule:MF_00435}.
Product Synonyms
Product (LegacyBRC) Product (RefSeq)
Operon
Refseq
GI Number Accession Blast Conserved Domains
GO Terms
String Network
Link to STRINGS STRINGS Network
MSMEG_2374
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