MSMEG_5427 MSMEG_5427 Ribose-phosphate pyrophosphokinase (RPPK) (EC 2.7.6.1) (5-phospho-D-ribosyl alpha-1-diphosphate) (Phosphoribosyl diphosphate synthase) (Phosphoribosyl pyrophosphate synthase)
Mycobacterium smegmatis (strain ATCC 700084 / mc(2)155)

Mycobacterium smegmatis (strain ATCC 700084 / mc(2)155)

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Summary

	Locus Tag	Symbol	Synonyms	Product	Protein Synonyms	Start	End	Strand	PubMed ID
MSMEG_5427	MSMEG_5427	prs	prs, MSMEG_5427, MSMEI_5278		Ribose-phosphate pyrophosphokinase (RPPK) (EC 2.7.6.1) (5-phospho-D-ribosyl alpha-1-diphosphate) (Phosphoribosyl diphosphate synthase) (Phosphoribosyl pyrophosphate synthase)				17295914, 18955433

Regulatory Modules

	Residual	Motif 1	Expression Plot
msm_bicluster_0604	0.51
msm_bicluster_0635	0.50

XReference

Uniprot	NCBI Gene	NCBI Protein	EnsemblBacteria	InterPro	EggNOG	OrthoDB
A0R3C8	4533925;	WP_003896824.1, YP_889666.1	ABK72893, AFP41720, AIU10446	IPR000842, IPR029099, IPR029057, IPR005946	COG0462, ENOG4105C5T	EOG6Z99XQ

Mutations

Line	Position	Effect	Impact	Class	Percent Frequency	AA

Transposon mutants

Title	Insert	TAG Module
NA

Homology

Orthologues	Paralogues

Functions

Catalytic Activity	KEGG Ontology	Pathways
ATP + D-ribose 5-phosphate = AMP + 5-phospho-alpha-D-ribose 1-diphosphate, ECO:0000256|HAMAP-Rule:MF_00583}.	msb:LJ00_26820, msg:MSMEI_5278, msm:MSMEG_5427	Metabolic intermediate biosynthesis, 5-phospho-alpha-D-ribose 1-diphosphate biosynthesis, 5-phospho-alpha-D-ribose 1-diphosphate from D-ribose 5-phosphate (route I): step 1/1. {ECO:0000256|HAMAP-Rule:MF_00583}.

Product Synonyms

Product (LegacyBRC)	Product (RefSeq)

Operon

Refseq

GI Number	Accession	Blast	Conserved Domains

GO Terms

GO:0006015 GO:0005524 GO:0005737 GO:0016301 GO:0000287 GO:0009165 GO:0009156 GO:0004749 -

GO:0006015

GO:0005524

GO:0005737

GO:0016301

GO:0000287

GO:0009165

GO:0009156

GO:0004749

String Network

Link to STRINGS	STRINGS Network
MSMEG_5427

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