Module 325 Residual: 0.59Mycobacterium smegmatis (strain ATCC 700084 / mc(2)155)

Summary

Residual	Motif 1 e-value	Motif 2 e-value	Conditions	Genes	version
0.59	7e-17	0.00000022	76	32	20160204

Motifs

Motif 1
	e-value: 7e-17
Motif 2
	e-value: 0.00000022

Module Plots

Members

MSMEG_6473 O-methyltransferase-like protein (Tetracenomycin polyketide synthesis O-methyltransferase TcmP) (EC 2.1.1.-)	MSMEG_6190 Metallo-beta-lactamase family protein (Putative hydrolase (Beta-lactamase-like))
MSMEG_6911 ABC transporter, ATP-binding protein GluA	MSMEG_6191 Putative endoribonuclease L-PSP family (Translation initiation inhibitor)
MSMEG_0649 Phosphate-import protein PhnD	MSMEG_1551 Uncharacterized protein
MSMEG_0806 Hydrolase	MSMEG_6909 Amino acid ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family protein (Polar amino acid ABC transporter, inner membrane subunit) (EC 4.2.1.51)
MSMEG_0807 Aminopeptidase Y Metallo peptidase MEROPS family M28A (EC 3.4.11.15) (Leupeptin-inactivating enzyme 1) (EC 3.4.24.-)	MSMEG_3041 Putative transferase (Thiopurine S-methyltransferase (Tpmt) superfamily protein)
MSMEG_6752 Glucanase (EC 3.2.1.-)	MSMEG_0762 Cytochrome P450 FAS1 (EC 1.14.-.-)
MSMEG_6753 Oxidoreductase, short chain dehydrogenase/reductase family protein (Short-chain dehydrogenase/reductase SDR)	MSMEG_6901 Uncharacterized protein
MSMEG_6119 Uncharacterized protein	MSMEG_5372 Sensor protein KdpD (EC 2.7.13.3)
MSMEG_3508 Hydrolase, alpha/beta hydrolase fold family protein	MSMEG_6767 Mycocerosic acid synthase (EC 2.3.1.111)
MSMEG_0647 Phosphate-import ATP-binding protein PhnC (EC 3.6.3.27)	MSMEG_0320 Phosphotriesterase php (Parathion hydrolase) (EC 3.1.8.1) (Putative phosphotriesterase)
MSMEG_0091 Putative transcriptional regulator	MSMEG_2136 Phosphoglucomutase PgmA (EC 5.4.2.2) (Phosphoglucomutase, alpha-D-glucose phosphate-specific) (EC 5.4.2.2)
MSMEG_0090 Membrane protein-like protein (Uncharacterized protein)	MSMEG_0650 HTH-type transcriptional repressor PhnF
MSMEG_0761 Conserved domain protein (Putative ferredoxin)	MSMEG_2179 Transcriptional regulator, TetR family (Transcriptional regulatory protein)
MSMEG_0092 Probable transcriptional regulatory protein (TetR-family transcriptional regulator)	MSMEG_2667 HpcH/HpaI aldolase/citrate lyase family protein, putative (EC 4.1.3.-)
MSMEG_2167 Aminopeptidase, putative (Peptidase M24) (EC 3.4.13.9)	MSMEG_3584 Conserved transmembrane transport protein MmpL1 (Membrane protein, MmpL family protein)
MSMEG_6192 Uncharacterized protein	MSMEG_0318 AMP-dependent synthetase and ligase

Conditions

KO_stationary.phase_rep2

Stationary.cultures.induced.to.express.I.SceI.for.45.minutes..T.45...ATc.

Biological.replicate.3.of.6..kanamycin.treatment

dcpA.knockout.rep2

Biological.replicate.4.of.6..negative.control

Biological.replicate.4.of.7..ethambutol.treatment

Bedaquiline.vs..DMSO.30min

MB100pruR.vs..MB100..rep.3

dosR.WT_Replicate1

KO_log.phase_rep2

Wild.type.rep2.y

dosR.WT_Replicate4

Wild.type.rep1.x

Wild.type.rep1.y

Biological.replicate.3.of.7..panaxydol.treatment

Biological.replicate.6.of.6..negative.control

WT.vs..DamtR.without.N_.dyeswap_rep2

MB100pruR.vs..MB100.rep.1

Biological.replicate.7.of.7..ethambutol.treatment

Biological.replicate.1.of.7..ethambutol.treatment

rel.knockout.rep2

rel.knockout.rep1

Bedaquiline.vs..DMSO..45min

MB100pruR.vs..MB100.rep.2

Biological.replicate.6.of.7..panaxydol.treatment

M..smegmatis.Acid.NO.treated

Biological.replicate.4.of.6..isoniazid.treatment

Biological.replicate.3.of.6..isoniazid.treatment

WT_log.phase_rep2

X0.6..vs..50..air.saturation.Replicate.3

Sub.MIC.INH

X0.6..vs..50..air.saturation.Replicate.4

M.smegmatis_mc2_155_dMSMEG_0166_study_mutant_rep3

M.smegmatis_mc2_155_dMSMEG_0166_study_mutant_rep2

mc2155.vs.Dcrp1.replicate.2

mc2155.vs.Dcrp1.replicate.3

Biological.replicate.1.of.6..kanamycin.treatment

Biological.replicate.1.of.7..panaxydol.treatment

Biological.replicate.3.of.6..negative.control

Biological.replicate.5.of.7..panaxydol.treatment

dcpA.knockout.rep1

Biological.replicate.5.of.6..negative.control

X3dbfcy5plogcy3slide601norm

Stationary.phase.cultures.induced.to.express.I.SceI.for.15.minutes..T.15...ATc.

stphcy3plogcy5slide581norm

WT_log.phase_rep1

Biological.replicate.4.of.7..panaxydol.treatment

X4dbfcy5plogcy3slide480norm

Biological.replicate.5.of.6..isoniazid.treatment

Biological.replicate.2.of.7..panaxydol.treatment

Biological.replicate.2.of.6..negative.control

WT_stationary.phase_rep1

Biological.replicate.6.of.6..isoniazid.treatment

X4XR.rep1

mc2155.pMind..vs.mc2155.pMind.6189.replicate.4

Biological.replicate.2.of.6..kanamycin.treatment

Biological.replicate.6.of.7..ethambutol.treatment

Biological.replicate.3.of.7..falcarinol.treatment

BatchCulture_LBTbroth_ExponentialPhase_Replicate2

BatchCulture_LBTbroth_ExponentialPhase_Replicate3

X3dbfcy5plogcy3slide603norm

mc2155.pMind..vs.mc2155.pMind.6189.replicate.2

Wild.type.rep3

BatchCulture_LBTbroth_ExponentialPhase_Replicate4

Log.phase.cultures.without.induction.of.I.SceI.expression..T.0...Atc.

Biological.replicate.1.of.7..falcarinol.treatment

Biological.replicate.1.of.6..negative.control

X2XR.rep2

DglnR_without.vs..with.N_dyeswap_rep1

JR121..pJR29.VapC..vs..JR121..pJR230..VapBC..rep3

JR121..pJR29.VapC..vs..JR121..pJR230..VapBC..rep2

BatchCulture_LBTbroth_StationaryPhase_Replicate1

M.smegmatis_mc2_155_dMSMEG_0166_study_wild.type_rep3

M.smegmatis_mc2_155_dMSMEG_0166_study_wild.type_rep2

M.smegmatis_mc2_155_dMSMEG_0166_study_wild.type_rep1

X4dbfcy3plogcy5slide903norm

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