******************************************************************************** MEME - Motif discovery tool ******************************************************************************** MEME version 4.10.0 (Release date: Wed May 21 10:35:36 2014 +1000) For further information on how to interpret these results or to get a copy of the MEME software please access http://meme.nbcr.net. This file may be used as input to the MAST algorithm for searching sequence databases for matches to groups of motifs. MAST is available for interactive use and downloading at http://meme.nbcr.net. ******************************************************************************** ******************************************************************************** REFERENCE ******************************************************************************** If you use this program in your research, please cite: Timothy L. Bailey and Charles Elkan, "Fitting a mixture model by expectation maximization to discover motifs in biopolymers", Proceedings of the Second International Conference on Intelligent Systems for Molecular Biology, pp. 28-36, AAAI Press, Menlo Park, California, 1994. ******************************************************************************** ******************************************************************************** TRAINING SET ******************************************************************************** DATAFILE= motifs/274/274.seqs.fa ALPHABET= ACGT Sequence name Weight Length Sequence name Weight Length ------------- ------ ------ ------------- ------ ------ 21659 1.0000 500 21908 1.0000 500 22272 1.0000 500 23034 1.0000 500 24021 1.0000 500 24946 1.0000 500 26393 1.0000 500 263987 1.0000 500 264149 1.0000 500 32713 1.0000 500 33432 1.0000 500 36884 1.0000 500 37559 1.0000 500 42194 1.0000 500 4955 1.0000 500 5004 1.0000 500 6727 1.0000 500 9206 1.0000 500 9384 1.0000 500 ******************************************************************************** ******************************************************************************** COMMAND LINE SUMMARY ******************************************************************************** This information can also be useful in the event you wish to report a problem with the MEME software. command: meme motifs/274/274.seqs.fa -oc motifs/274 -dna -minw 12 -maxw 21 -nmotifs 3 -maxsize 500000 model: mod= zoops nmotifs= 3 evt= inf object function= E-value of product of p-values width: minw= 12 maxw= 21 minic= 0.00 width: wg= 11 ws= 1 endgaps= yes nsites: minsites= 2 maxsites= 19 wnsites= 0.8 theta: prob= 1 spmap= uni spfuzz= 0.5 global: substring= yes branching= no wbranch= no em: prior= dirichlet b= 0.01 maxiter= 50 distance= 1e-05 data: n= 9500 N= 19 strands: + sample: seed= 0 seqfrac= 1 Letter frequencies in dataset: A 0.253 C 0.241 G 0.237 T 0.270 Background letter frequencies (from dataset with add-one prior applied): A 0.253 C 0.241 G 0.237 T 0.270 ******************************************************************************** ******************************************************************************** MOTIF 1 MEME width = 16 sites = 16 llr = 184 E-value = 6.4e-006 ******************************************************************************** -------------------------------------------------------------------------------- Motif 1 Description -------------------------------------------------------------------------------- Simplified A :33:3:::5235::1: pos.-specific C ::4::::11::1:::: probability G a41a3:96:36:9848 matrix T :33:4a1346141253 bits 2.1 * * 1.9 * * * 1.7 * * * 1.5 * * ** * Relative 1.2 * * ** ** * Entropy 1.0 * * ** ** * (16.6 bits) 0.8 * * *** * ** * 0.6 * * *********** 0.4 ** ************* 0.2 ** ************* 0.0 ---------------- Multilevel GGCGTTGGATGAGGTG consensus AA G TTGAT GT sequence TT A -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif 1 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Start P-value Site ------------- ----- --------- ---------------- 32713 255 6.60e-08 GGAGTGTGCA GGAGGTGGAGGAGGGG AGTCAACGTC 33432 362 7.37e-08 ATTCAGGAAC GACGGTGGATAAGGTG AGTTATTAAT 264149 130 2.26e-07 TGGAAATTGT GGAGATGTTTGTGGTG ATGGCAACTC 21659 188 3.34e-07 TGTTGTTGGT GGAGTTGGAGGAGGAG GCATGGTGTG 42194 352 4.96e-07 AATTTTATGA GTTGATGGATAAGGTG AGTGTGTTGC 37559 227 4.96e-07 AGCCGCAAAA GAGGTTGTTTGTGGTG CTTCGGGCAG 5004 183 1.09e-06 GCGAAGGAGT GGTGGTGGAGGTGTGG AAGGGGGGTC 21908 230 1.48e-06 TGTCATCGTC GTCGTTGTATTTGGGG GCTATATGAT 23034 39 1.96e-06 ATGTTTGTAC GACGGTGGTTTTGGTT GCGTACTACT 22272 303 3.33e-06 GGAGGTTGCT GTTGTTGGTAGCGGTG CTGCCGAGCG 6727 297 3.61e-06 AACATGGTTT GTCGATTTTTGAGGGG TGTGTGGCGT 263987 47 5.71e-06 GCCCTCCCTC GGTGTTGTTTGTTGTT GTCCTACACC 36884 281 7.55e-06 TGTCGGGAGT GACGTTTGAAGAGTGG TAAAGACACA 9384 202 1.04e-05 CGAATACTAT GGGGATGGATGAGTAT TGGGGGTCTT 24021 449 1.32e-05 AAAGCATCGC GGAGGTGGCAAAGGGT TGCTTATGCT 4955 57 2.10e-05 TTCTTGTCTT GACGTTGCTGATTGTG TAACTTTTTG -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif 1 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- 32713 6.6e-08 254_[+1]_230 33432 7.4e-08 361_[+1]_123 264149 2.3e-07 129_[+1]_355 21659 3.3e-07 187_[+1]_297 42194 5e-07 351_[+1]_133 37559 5e-07 226_[+1]_258 5004 1.1e-06 182_[+1]_302 21908 1.5e-06 229_[+1]_255 23034 2e-06 38_[+1]_446 22272 3.3e-06 302_[+1]_182 6727 3.6e-06 296_[+1]_188 263987 5.7e-06 46_[+1]_438 36884 7.6e-06 280_[+1]_204 9384 1e-05 201_[+1]_283 24021 1.3e-05 448_[+1]_36 4955 2.1e-05 56_[+1]_428 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif 1 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF 1 width=16 seqs=16 32713 ( 255) GGAGGTGGAGGAGGGG 1 33432 ( 362) GACGGTGGATAAGGTG 1 264149 ( 130) GGAGATGTTTGTGGTG 1 21659 ( 188) GGAGTTGGAGGAGGAG 1 42194 ( 352) GTTGATGGATAAGGTG 1 37559 ( 227) GAGGTTGTTTGTGGTG 1 5004 ( 183) GGTGGTGGAGGTGTGG 1 21908 ( 230) GTCGTTGTATTTGGGG 1 23034 ( 39) GACGGTGGTTTTGGTT 1 22272 ( 303) GTTGTTGGTAGCGGTG 1 6727 ( 297) GTCGATTTTTGAGGGG 1 263987 ( 47) GGTGTTGTTTGTTGTT 1 36884 ( 281) GACGTTTGAAGAGTGG 1 9384 ( 202) GGGGATGGATGAGTAT 1 24021 ( 449) GGAGGTGGCAAAGGGT 1 4955 ( 57) GACGTTGCTGATTGTG 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif 1 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 4 w= 16 n= 9215 bayes= 10.906 E= 6.4e-006 -1064 -1064 208 -1064 31 -1064 89 -11 -2 64 -92 -11 -1064 -1064 208 -1064 -2 -1064 40 70 -1064 -1064 -1064 189 -1064 -1064 189 -111 -1064 -194 140 21 98 -194 -1064 70 -43 -1064 8 106 -2 -1064 140 -111 98 -194 -1064 70 -1064 -1064 189 -111 -1064 -1064 178 -53 -101 -1064 66 89 -1064 -1064 166 -11 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif 1 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 4 w= 16 nsites= 16 E= 6.4e-006 0.000000 0.000000 1.000000 0.000000 0.312500 0.000000 0.437500 0.250000 0.250000 0.375000 0.125000 0.250000 0.000000 0.000000 1.000000 0.000000 0.250000 0.000000 0.312500 0.437500 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.875000 0.125000 0.000000 0.062500 0.625000 0.312500 0.500000 0.062500 0.000000 0.437500 0.187500 0.000000 0.250000 0.562500 0.250000 0.000000 0.625000 0.125000 0.500000 0.062500 0.000000 0.437500 0.000000 0.000000 0.875000 0.125000 0.000000 0.000000 0.812500 0.187500 0.125000 0.000000 0.375000 0.500000 0.000000 0.000000 0.750000 0.250000 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif 1 regular expression -------------------------------------------------------------------------------- G[GAT][CAT]G[TGA]TG[GT][AT][TG][GA][AT]GG[TG][GT] -------------------------------------------------------------------------------- Time 3.33 secs. ******************************************************************************** ******************************************************************************** MOTIF 2 MEME width = 19 sites = 19 llr = 203 E-value = 4.8e-002 ******************************************************************************** -------------------------------------------------------------------------------- Motif 2 Description -------------------------------------------------------------------------------- Simplified A 1283522576552381a63 pos.-specific C 8413318324414629:37 probability G :2::11:11:1421:::1: matrix T 131426111:::211::1: bits 2.1 * 1.9 * 1.7 ** 1.5 ** Relative 1.2 * * ** * Entropy 1.0 * * * * *** * (15.4 bits) 0.8 * * * ** *** * 0.6 * * * **** *** * 0.4 * ** ******* ****** 0.2 * ***************** 0.0 ------------------- Multilevel CCATATCAAAAACCACAAC consensus T CCA C CCGGA CA sequence G AT T -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif 2 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Start P-value Site ------------- ----- --------- ------------------- 26393 469 2.83e-10 AGCCACCCAA CGATATCAAACGCCACAAC ACAATATTGA 22272 481 1.36e-08 ACGGAGACAC CCAACTCCAACACAACAAC C 263987 201 3.05e-08 GCCTTTACGT CCACATCCACCACCACATC CATTTCACGA 21908 481 4.79e-08 TTGACGGTGA CGACAACAACAGACACAAC C 24946 409 1.11e-07 CGTCCCAAAT CTATCTCGACAGTCACAAC AACTGGCTCT 23034 475 1.31e-06 TGAATCATCA ACATTTCAACCACCCCACC ACCACTC 32713 302 2.15e-06 CAAATGGAAA CAACAACGGAAACAACAAC GGCGCTACCA 264149 453 2.61e-06 CTCGTCCACG CTCAATCAACAACAACAGC ACTAGTAGCT 33432 300 3.15e-06 ACGACCGCTT CGATACCTCACGGCACAAC CGCAACTCGC 37559 107 5.41e-06 GACTAGCTAT CCAATTCAACCACTTCAAC TCCAATATCT 24021 352 6.99e-06 ACCGCAAAGC CGACAAACAACGACACACA AACAAGGAAG 21659 384 1.44e-05 ATCGTTGGAT CAAAATAAAAACTGACAAA GACACTCGAA 36884 155 1.56e-05 TCATTTCAAG CTACGGCCACCGCCACACA CCCTCCACGC 9206 479 1.68e-05 TATCATTACA CCAATCAAGAAAGCACAAA ACA 5004 358 2.10e-05 CAAACGCAAC CTTTATCACAACGAACACC AGCTCTTGAG 6727 477 3.44e-05 CTTCCCTGCT TCCTCTCAACAATAACACA CAGCC 42194 453 3.94e-05 TTCAACGTAT CCATCTTCCAAGGCAAAAC TCGTAACGTT 9384 457 7.87e-05 TCCTGATTCA AAATCTCATAAATCCCATC CTTGTTCCTC 4955 164 9.39e-05 AGCAGCTCTC CTACTACTAAGAAGCCAAC TTTAAATTGT -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif 2 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- 26393 2.8e-10 468_[+2]_13 22272 1.4e-08 480_[+2]_1 263987 3e-08 200_[+2]_281 21908 4.8e-08 480_[+2]_1 24946 1.1e-07 408_[+2]_73 23034 1.3e-06 474_[+2]_7 32713 2.2e-06 301_[+2]_180 264149 2.6e-06 452_[+2]_29 33432 3.2e-06 299_[+2]_182 37559 5.4e-06 106_[+2]_375 24021 7e-06 351_[+2]_130 21659 1.4e-05 383_[+2]_98 36884 1.6e-05 154_[+2]_327 9206 1.7e-05 478_[+2]_3 5004 2.1e-05 357_[+2]_124 6727 3.4e-05 476_[+2]_5 42194 3.9e-05 452_[+2]_29 9384 7.9e-05 456_[+2]_25 4955 9.4e-05 163_[+2]_318 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif 2 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF 2 width=19 seqs=19 26393 ( 469) CGATATCAAACGCCACAAC 1 22272 ( 481) CCAACTCCAACACAACAAC 1 263987 ( 201) CCACATCCACCACCACATC 1 21908 ( 481) CGACAACAACAGACACAAC 1 24946 ( 409) CTATCTCGACAGTCACAAC 1 23034 ( 475) ACATTTCAACCACCCCACC 1 32713 ( 302) CAACAACGGAAACAACAAC 1 264149 ( 453) CTCAATCAACAACAACAGC 1 33432 ( 300) CGATACCTCACGGCACAAC 1 37559 ( 107) CCAATTCAACCACTTCAAC 1 24021 ( 352) CGACAAACAACGACACACA 1 21659 ( 384) CAAAATAAAAACTGACAAA 1 36884 ( 155) CTACGGCCACCGCCACACA 1 9206 ( 479) CCAATCAAGAAAGCACAAA 1 5004 ( 358) CTTTATCACAACGAACACC 1 6727 ( 477) TCCTCTCAACAATAACACA 1 42194 ( 453) CCATCTTCCAAGGCAAAAC 1 9384 ( 457) AAATCTCATAAATCCCATC 1 4955 ( 164) CTACTACTAAGAAGCCAAC 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif 2 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 4 w= 19 n= 9158 bayes= 8.90989 E= 4.8e-002 -126 181 -1089 -236 -68 61 -17 -4 174 -119 -1089 -236 6 39 -1089 64 91 13 -217 -36 -26 -119 -217 123 -68 171 -1089 -236 106 13 -117 -136 144 -61 -117 -236 120 81 -1089 -1089 106 81 -217 -1089 106 -119 64 -1089 -68 81 -17 -36 6 127 -117 -236 164 -61 -1089 -236 -226 198 -1089 -1089 198 -1089 -1089 -1089 120 13 -217 -136 6 161 -1089 -1089 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif 2 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 4 w= 19 nsites= 19 E= 4.8e-002 0.105263 0.842105 0.000000 0.052632 0.157895 0.368421 0.210526 0.263158 0.842105 0.105263 0.000000 0.052632 0.263158 0.315789 0.000000 0.421053 0.473684 0.263158 0.052632 0.210526 0.210526 0.105263 0.052632 0.631579 0.157895 0.789474 0.000000 0.052632 0.526316 0.263158 0.105263 0.105263 0.684211 0.157895 0.105263 0.052632 0.578947 0.421053 0.000000 0.000000 0.526316 0.421053 0.052632 0.000000 0.526316 0.105263 0.368421 0.000000 0.157895 0.421053 0.210526 0.210526 0.263158 0.578947 0.105263 0.052632 0.789474 0.157895 0.000000 0.052632 0.052632 0.947368 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 0.578947 0.263158 0.052632 0.105263 0.263158 0.736842 0.000000 0.000000 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif 2 regular expression -------------------------------------------------------------------------------- C[CTG]A[TCA][ACT][TA]C[AC]A[AC][AC][AG][CGT][CA]ACA[AC][CA] -------------------------------------------------------------------------------- Time 6.45 secs. ******************************************************************************** ******************************************************************************** MOTIF 3 MEME width = 20 sites = 6 llr = 106 E-value = 6.7e+000 ******************************************************************************** -------------------------------------------------------------------------------- Motif 3 Description -------------------------------------------------------------------------------- Simplified A ::2::33::727::273::: pos.-specific C a::8::3a::3:a:::::32 probability G :3:2a72:a32::8727a58 matrix T :78:::2:::33:222::2: bits 2.1 * * ** * * 1.9 * * ** * * 1.7 * * ** * * 1.5 * ** ** ** * * Relative 1.2 * *** ** ** * * Entropy 1.0 ****** *** *** ** * (25.6 bits) 0.8 ****** *** ******* * 0.6 ****** *** ********* 0.4 ****** *** ********* 0.2 ****** *** ********* 0.0 -------------------- Multilevel CTTCGGACGACACGGAGGGG consensus G AC GTT A C sequence -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif 3 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Start P-value Site ------------- ----- --------- -------------------- 5004 289 9.75e-11 TAGTATTTTT CTTGGGACGACACGGAGGGG GTAAACTACA 23034 379 2.68e-09 TCTTTTGTTA CTTCGAACGGAACGAAGGGG TGGTGTTACA 6727 242 4.19e-09 CTGGAGCGAC CTTCGGGCGGCTCGGAGGCC TGTTCGGGCG 22272 152 5.92e-09 GACTCGGCTT CTTCGGCCGATTCTGTGGCG GAGAGATCTG 21659 318 7.98e-09 AAGAGGAGGA CGACGGCCGAGACGGAAGTG AGAGCAATGG 36884 335 2.05e-08 TGTGGCTCTG CGTCGATCGATACGTGAGGG GAAGCGAGTC -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif 3 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- 5004 9.7e-11 288_[+3]_192 23034 2.7e-09 378_[+3]_102 6727 4.2e-09 241_[+3]_239 22272 5.9e-09 151_[+3]_329 21659 8e-09 317_[+3]_163 36884 2e-08 334_[+3]_146 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif 3 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF 3 width=20 seqs=6 5004 ( 289) CTTGGGACGACACGGAGGGG 1 23034 ( 379) CTTCGAACGGAACGAAGGGG 1 6727 ( 242) CTTCGGGCGGCTCGGAGGCC 1 22272 ( 152) CTTCGGCCGATTCTGTGGCG 1 21659 ( 318) CGACGGCCGAGACGGAAGTG 1 36884 ( 335) CGTCGATCGATACGTGAGGG 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif 3 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 4 w= 20 n= 9139 bayes= 11.0196 E= 6.7e+000 -923 205 -923 -923 -923 -923 49 130 -60 -923 -923 162 -923 179 -50 -923 -923 -923 208 -923 40 -923 149 -923 40 47 -50 -69 -923 205 -923 -923 -923 -923 208 -923 140 -923 49 -923 -60 47 -50 30 140 -923 -923 30 -923 205 -923 -923 -923 -923 182 -69 -60 -923 149 -69 140 -923 -50 -69 40 -923 149 -923 -923 -923 208 -923 -923 47 108 -69 -923 -53 182 -923 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif 3 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 4 w= 20 nsites= 6 E= 6.7e+000 0.000000 1.000000 0.000000 0.000000 0.000000 0.000000 0.333333 0.666667 0.166667 0.000000 0.000000 0.833333 0.000000 0.833333 0.166667 0.000000 0.000000 0.000000 1.000000 0.000000 0.333333 0.000000 0.666667 0.000000 0.333333 0.333333 0.166667 0.166667 0.000000 1.000000 0.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.666667 0.000000 0.333333 0.000000 0.166667 0.333333 0.166667 0.333333 0.666667 0.000000 0.000000 0.333333 0.000000 1.000000 0.000000 0.000000 0.000000 0.000000 0.833333 0.166667 0.166667 0.000000 0.666667 0.166667 0.666667 0.000000 0.166667 0.166667 0.333333 0.000000 0.666667 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.333333 0.500000 0.166667 0.000000 0.166667 0.833333 0.000000 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif 3 regular expression -------------------------------------------------------------------------------- C[TG]TCG[GA][AC]CG[AG][CT][AT]CGGA[GA]G[GC]G -------------------------------------------------------------------------------- Time 9.67 secs. ******************************************************************************** ******************************************************************************** SUMMARY OF MOTIFS ******************************************************************************** -------------------------------------------------------------------------------- Combined block diagrams: non-overlapping sites with p-value < 0.0001 -------------------------------------------------------------------------------- SEQUENCE NAME COMBINED P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- 21659 1.59e-09 187_[+1(3.34e-07)]_114_\ [+3(7.98e-09)]_46_[+2(1.44e-05)]_98 21908 1.07e-06 229_[+1(1.48e-06)]_235_\ [+2(4.79e-08)]_1 22272 1.55e-11 26_[+1(4.97e-05)]_109_\ [+3(5.92e-09)]_131_[+1(3.33e-06)]_162_[+2(1.36e-08)]_1 23034 3.23e-10 38_[+1(1.96e-06)]_220_\ [+3(6.37e-05)]_84_[+3(2.68e-09)]_76_[+2(1.31e-06)]_7 24021 4.99e-04 351_[+2(6.99e-06)]_78_\ [+1(1.32e-05)]_36 24946 6.60e-04 408_[+2(1.11e-07)]_73 26393 5.39e-06 419_[+2(8.86e-05)]_30_\ [+2(2.83e-10)]_13 263987 5.54e-06 46_[+1(5.71e-06)]_138_\ [+2(3.05e-08)]_281 264149 2.32e-06 129_[+1(2.26e-07)]_307_\ [+2(2.61e-06)]_29 32713 5.07e-06 254_[+1(6.60e-08)]_31_\ [+2(2.15e-06)]_180 33432 3.38e-06 299_[+2(3.15e-06)]_43_\ [+1(7.37e-08)]_123 36884 7.17e-08 154_[+2(1.56e-05)]_107_\ [+1(7.55e-06)]_38_[+3(2.05e-08)]_146 37559 3.06e-05 43_[+1(1.11e-05)]_47_[+2(5.41e-06)]_\ 101_[+1(4.96e-07)]_236_[+2(4.49e-05)]_3 42194 1.52e-04 246_[+1(8.58e-05)]_89_\ [+1(4.96e-07)]_85_[+2(3.94e-05)]_29 4955 1.30e-02 56_[+1(2.10e-05)]_91_[+2(9.39e-05)]_\ 318 5004 1.12e-10 182_[+1(1.09e-06)]_90_\ [+3(9.75e-11)]_49_[+2(2.10e-05)]_124 6727 1.75e-08 241_[+3(4.19e-09)]_35_\ [+1(3.61e-06)]_164_[+2(3.44e-05)]_5 9206 3.49e-02 478_[+2(1.68e-05)]_3 9384 1.85e-03 201_[+1(1.04e-05)]_239_\ [+2(7.87e-05)]_25 -------------------------------------------------------------------------------- ******************************************************************************** ******************************************************************************** Stopped because nmotifs = 3 reached. ******************************************************************************** CPU: seaotter.hsd1.wa.comcast.net ********************************************************************************