12578-GO

Definition: 
cell cycle checkpoint
regulation of cyclin-dependent protein serine/threonine kinase activity
G1/S transition of mitotic cell cycle
protein polyubiquitination
granular component
negative regulation of cell-matrix adhesion
p53 binding
DNA binding
sequence-specific DNA binding transcription factor activity
cyclin-dependent protein serine/threonine kinase inhibitor activity
protein binding
nucleus
nucleoplasm
nucleolus
cytoplasm
mitochondrion
transcription, DNA-templated
regulation of transcription, DNA-templated
rRNA processing
negative regulation of protein kinase activity
apoptotic process
activation of cysteine-type endopeptidase activity involved in apoptotic process
cell cycle
cell cycle arrest
aging
cell aging
transcription factor binding
negative regulation of cell proliferation
epidermis development
apoptotic mitochondrial changes
rRNA transcription
response to organonitrogen compound
regulation of G2/M transition of mitotic cell cycle
regulation of gene expression
response to organic cyclic compound
nuclear body
protein kinase binding
negative regulation of cell growth
negative regulation of B cell proliferation
regulation of protein stability
protein destabilization
negative regulation of NF-kappaB transcription factor activity
negative regulation of immature T cell proliferation in thymus
positive regulation of protein sumoylation
negative regulation of mammary gland epithelial cell proliferation
positive regulation of smooth muscle cell apoptotic process
somatic stem cell maintenance
senescence-associated heterochromatin focus
senescence-associated heterochromatin focus assembly
negative regulation of phosphorylation
response to drug
protein complex
positive regulation of DNA damage response, signal transduction by p53 class mediator
negative regulation of cyclin-dependent protein serine/threonine kinase activity
negative regulation of cell cycle
negative regulation of transcription, DNA-templated
positive regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
regulation of nucleocytoplasmic transport
regulation of protein export from nucleus
somatic stem cell division
protein stabilization
NF-kappaB binding
positive regulation of sequence-specific DNA binding transcription factor activity
negative regulation of ubiquitin-protein ligase activity
ubiquitin-protein ligase inhibitor activity
positive regulation of apoptotic process involved in mammary gland involution
cellular response to hydrogen peroxide
protein K63-linked ubiquitination
positive regulation of cell cycle arrest
cellular senescence
replicative senescence
MDM2/MDM4 family protein binding
regulation of apoptotic DNA fragmentation
positive regulation of macrophage apoptotic process
positive regulation of cellular senescence