21340-GO
Gene ID:
RNA polymerase I CORE element sequence-specific DNA binding
Details:
Interacting selectively and non-covalently with the regulatory region composed of the transcription start site and binding sites for transcription factors of the RNA polymerase I transcription machinery. This site is often referred to as the CORE element. In mammalian cells, the CORE element functions in conjunction with the Upstream Control Element (UCE), while in fungi, protozoa, and plants, the CORE element functions without a UCE. [GOC:txnOH, PMID:12865296, PMID:14969726, PMID:8057832]
Evidence Code: