GO:0002291

T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell

Details: 
The change in morphology and behavior of a mature or immature T cell resulting from exposure to an antigen for which its T cell receptor is specific bound to an MHC molecule on an antigen presenting cell, leading to the initiation or perpetuation of an immune response. [GOC:add, ISBN:0781735149]
Evidence Code: 
IEA