GO:0008263 | Macrophage Network Portal

pyrimidine-specific mismatch base pair DNA N-glycosylase activity

Details:

Catalysis of the removal of mismatched pyrimidine bases in DNA. Enzymes with this activity recognize and remove pyrimidines present in mismatches by cleaving the N-C1' glycosidic bond between the target damaged DNA base and the deoxyribose sugar. The reaction releases a free base and leaves an apyrimidinic (AP) site. [GOC:elh, PMID:9224623]