GO:0016591

DNA-directed RNA polymerase II, holoenzyme

Details: 
Large protein complex composed of the RNA polymerase core complex and a variety of other proteins including transcription factor complexes TFIIA, D, E, F, and H which are required for promoter recognition, and the Mediator subcomplex. Catalyzes the synthesis of eukaryotic pre-mRNA. [GOC:jl, PMID:15196470, Wikipedia:Rna_polymerase_ii]
Evidence Code: