GO:0017183

peptidyl-diphthamide biosynthetic process from peptidyl-histidine

Details: 
The modification of peptidyl-histidine to 2'-(3-carboxamido-3-(trimethylammonio)propyl)-L-histidine, known as diphthamide, found in translation elongation factor eEF-2. [RESID:AA0040]
Evidence Code: 
ISS