14119-GO
Gene ID:
sequestering of TGFbeta in extracellular matrix
Details:
Confining TGFbeta to the extracellular matrix (ECM) such that it is separated from other components of the signaling pathway, including its cell surface receptor. TGFbeta is secreted as part of a latent complex that is targeted to the extracellular matrix through latent-TGFbeta-binding protein (LTBP)-mediated association with matrix proteins. [GOC:bf, GOC:BHF, GOC:signaling, PMID:12482908, PMID:20855508]
Evidence Code: