226409-GO
Gene ID:
DNA rewinding
Details:
The process in which interchain hydrogen bonds between two single-stranded DNA (ssDNA) are reformed to regenerate double-stranded DNA (dsDNA). ssDNA is often bound and stabilized by proteins such as replication protein A (RPA) to form ssDNA bubbles. The bubbles can be rewound by ATP-dependent motors to reform base pairs between strands and thus dsDNA. [PMID:21078962, PMID:22704558, PMID:22705370, PMID:22759634]
Evidence Code: