GO:0036324

Any series of molecular signals initiated by the binding of an extracellular ligand to a vascular endothelial growth factor receptor-2 (VEGFR-2) located on the surface of the receiving cell, and ending with regulation of a downstream cellular process, e.g. transcription. [GOC:bf, GOC:uh, PMID:12967471, PR:000002112, Wikipedia:Kinase_insert_domain_receptor, Wikipedia:VEGF_receptors]