12575-GO

Definition: 
regulation of cyclin-dependent protein serine/threonine kinase activity
G1/S transition of mitotic cell cycle
G2/M transition of mitotic cell cycle
cyclin-dependent protein kinase holoenzyme complex
protein kinase inhibitor activity
cyclin-dependent protein serine/threonine kinase inhibitor activity
protein binding
intracellular
nucleus
cytoplasm
cytosol
protein phosphorylation
cellular response to DNA damage stimulus
DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest
cell cycle
cell cycle arrest
regulation of mitotic cell cycle
negative regulation of cell proliferation
response to UV
negative regulation of gene expression
kinase activity
phosphorylation
transferase activity
cyclin-dependent protein kinase activating kinase activity
negative regulation of cell growth
cyclin binding
positive regulation of B cell proliferation
cellular response to extracellular stimulus
protein complex binding
regulation of protein import into nucleus, translocation
negative regulation of phosphorylation
intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator
negative regulation of apoptotic process
positive regulation of programmed cell death
negative regulation of cyclin-dependent protein serine/threonine kinase activity
positive regulation of protein kinase activity
metal ion binding
positive regulation of fibroblast proliferation
regulation of cell cycle
PCNA-p21 complex
cellular response to ionizing radiation
mitotic cell cycle arrest
cellular senescence
regulation of DNA biosynthetic process
positive regulation of reactive oxygen species metabolic process