PITA_2 megaCluster: 10 Residual: 0.15 | Macrophage Network Portal

Summary

Title	Cluster	Residual	Bicluster Conditions	Residual Permutation P-Value	Var. Exp. First PC	Var. Exp. First PC Perm. P-Value
PITA_2	10	0.15	15	0	0.958558	0

Members

Displaying 1 - 38 of 38

104444 REX2, RNA exonuclease 2 homolog (S. cerevisiae) Details for - - REX2, RNA exonuclease 2 homolog (S. cerevisiae) GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 104444 Tuberculist Genomic Region	110074 deoxyuridine triphosphatase Details for RP23-216B20.3 - deoxyuridine triphosphatase GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 110074 Tuberculist Genomic Region
12144 Bloom syndrome, RecQ helicase-like Details for - - Bloom syndrome, RecQ helicase-like GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 12144 Tuberculist Genomic Region	12189 breast cancer 1 Details for RP23-328K2.8 - breast cancer 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 12189 Tuberculist Genomic Region
12428 cyclin A2 Details for - - cyclin A2 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 12428 Tuberculist Genomic Region	12534 cyclin-dependent kinase 1 Details for - - cyclin-dependent kinase 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 12534 Tuberculist Genomic Region
12544 cell division cycle 45 Details for - - cell division cycle 45 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 12544 Tuberculist Genomic Region	13361 dihydrofolate reductase Details for - - dihydrofolate reductase GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 13361 Tuberculist Genomic Region
16881 ligase I, DNA, ATP-dependent Details for - - ligase I, DNA, ATP-dependent GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 16881 Tuberculist Genomic Region	20135 ribonucleotide reductase M2 Details for - - ribonucleotide reductase M2 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 20135 Tuberculist Genomic Region
20419 Shc SH2-domain binding protein 1 Details for - - Shc SH2-domain binding protein 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 20419 Tuberculist Genomic Region	20937 suppressor of variegation 3-9 homolog 1 (Drosophila) Details for RP23-27I6.1 - suppressor of variegation 3-9 homolog 1 (Drosophila) GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 20937 Tuberculist Genomic Region
211651 Fanconi anemia, complementation group D2 Details for - - Fanconi anemia, complementation group D2 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 211651 Tuberculist Genomic Region	218121 membrane bound O-acyltransferase domain containing 1 Details for RP23-195A2.1 - membrane bound O-acyltransferase domain containing 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 218121 Tuberculist Genomic Region
234258 nei like 3 (E. coli) Details for - - nei like 3 (E. coli) GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 234258 Tuberculist Genomic Region	237877 ATPase family, AAA domain containing 5 Details for RP23-328O2.1 - ATPase family, AAA domain containing 5 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 237877 Tuberculist Genomic Region
237911 BRCA1 interacting protein C-terminal helicase 1 Details for RP23-36C4.3 - BRCA1 interacting protein C-terminal helicase 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 237911 Tuberculist Genomic Region	242705 E2F transcription factor 2 Details for RP23-118A9.2 - E2F transcription factor 2 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 242705 Tuberculist Genomic Region
54633 polyglutamine binding protein 1 Details for RP23-443E19.4 - polyglutamine binding protein 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 54633 Tuberculist Genomic Region	56150 MAD2 mitotic arrest deficient-like 1 Details for - - MAD2 mitotic arrest deficient-like 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 56150 Tuberculist Genomic Region
60530 fidgetin-like 1 Details for RP23-373H2.1 - fidgetin-like 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 60530 Tuberculist Genomic Region	66131 timeless interacting protein Details for - - timeless interacting protein GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 66131 Tuberculist Genomic Region
66140 spindle and kinetochore associated complex subunit 2 Details for RP23-352L3.5 - spindle and kinetochore associated complex subunit 2 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 66140 Tuberculist Genomic Region	66929 ASF1 anti-silencing function 1 homolog B (S. cerevisiae) Details for - - ASF1 anti-silencing function 1 homolog B (S. cerevisiae) GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 66929 Tuberculist Genomic Region
70218 kinesin family member 18B Details for RP23-463E7.6 - kinesin family member 18B GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 70218 Tuberculist Genomic Region	71988 establishment of cohesion 1 homolog 2 (S. cerevisiae) Details for - - establishment of cohesion 1 homolog 2 (S. cerevisiae) GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 71988 Tuberculist Genomic Region
72155 centromere protein N Details for - - centromere protein N GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 72155 Tuberculist Genomic Region	74016 PHD finger protein 19 Details for RP23-9N11.3 - PHD finger protein 19 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 74016 Tuberculist Genomic Region
78833 GINS complex subunit 3 (Psf3 homolog) Details for - - GINS complex subunit 3 (Psf3 homolog) GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 78833 Tuberculist Genomic Region	102920 centromere protein I Details for RP23-162B19.4 - centromere protein I GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 102920 Tuberculist Genomic Region
12235 budding uninhibited by benzimidazoles 1 homolog (S. cerevisiae) Details for RP23-189N15.7 - budding uninhibited by benzimidazoles 1 homolog (S. cerevisiae) GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 12235 Tuberculist Genomic Region	12545 cell division cycle 7 (S. cerevisiae) Details for - - cell division cycle 7 (S. cerevisiae) GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 12545 Tuberculist Genomic Region
13605 ect2 oncogene Details for - - ect2 oncogene GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 13605 Tuberculist Genomic Region	19075 DNA primase, p49 subunit Details for - - DNA primase, p49 subunit GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 19075 Tuberculist Genomic Region
20873 polo-like kinase 4 Details for - - polo-like kinase 4 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 20873 Tuberculist Genomic Region	20877 aurora kinase B Details for RP23-19I2.1 - aurora kinase B GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 20877 Tuberculist Genomic Region
231506 lin-54 homolog (C. elegans) Details for - - lin-54 homolog (C. elegans) GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 231506 Tuberculist Genomic Region	27214 DBF4 homolog (S. cerevisiae) Details for - - DBF4 homolog (S. cerevisiae) GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 27214 Tuberculist Genomic Region

TFBS DB TF

TFs	percTargets	pValue
V_NFY_Q6_M00185	0.368421	0.000000549

GO Terms

Displaying 1 - 1 of 1

GO Terms
NA

Upstream MEME Motif

Motif1 E-Value	Motif1 Consensus	Motif1 Matches	Motif2 E-Value	Motif2 Consensus	Motif2 Matches
0.00000052	WAGWAAANAANA	V$FOXA2_04_M02749, V$FOXL1_04_M02753, V$FOXK1_03_M02752, V$HNF3B_Q6_M02014, V$FOXO3A_Q1_M01137, V$FOXO1_02_M00474, V$ZFP105_03_M02827, V$FOXJ1_03_M02750, V$HNF3_Q6_01_M01012, V$XFD1_01_M00267, V$FOXO3_01_M00477, V$FOXO4_02_M00476, V$FOXO1_Q5_M01216, Foxa2.1, Foxj3.2, Foxk1.1, Foxl1.1, Zfp105.1, FOXC1_forkhead_DBD_dimeric_13_1	75	NATYTTTNAAAA	NA

Upstream Weeder Motif

Motif1 Score	Motif1 Consensus	Motif1 Matches	Motif2 Score	Motif2 Consensus	Motif2 Matches
1.4	TTCGCG	V$E2F_Q6_M00427, V$E2F1_Q6_01_M00940, V$E2F_Q4_M00426, V$E2F_01_M00024, V$E2F_Q3_M00425, V$E2F1_Q6_M00431, V$E2F4DP1_01_M00738, V$E2F_Q4_02_M00939, V$E2F_Q3_01_M00918, V$E2F_03_M00516, V$E2F_02_M00050, V$E2F_Q4_01_M00919, V$E2F1DP1RB_01_M00740, V$E2F_Q6_01_M00920, V$E2F4DP2_01_M00739, V$E2F1DP1_01_M00736	1.47	TTCCGCGC	NA

3p UTR Weeder

Motif1 E-Value	Motif1 Consensus	Motif1 Matches	Motif1 Model	Motif2 E-Value	Motif2 Consensus	Motif2 Matches	Motif2 Model
0.47	ATAATA	NA	NA	0.58	AATAATAT	NA	NA

3p UTR PITA

miRNAs	percTargets	pValue
NA

3p UTR TargetScan

miRNAs	percTargets	pValue
mmu-miR-369-3p	0.4	0.0000365

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