PITA_4 megaCluster: 11 Residual: 0.13 | Macrophage Network Portal

Summary

Title	Cluster	Residual	Bicluster Conditions	Residual Permutation P-Value	Var. Exp. First PC	Var. Exp. First PC Perm. P-Value
PITA_4	11	0.13	15	0	0.972104	0

Members

Displaying 1 - 22 of 22

108671 DnaJ (Hsp40) homolog, subfamily C, member 9 Details for - - DnaJ (Hsp40) homolog, subfamily C, member 9 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 108671 Tuberculist Genomic Region	114663 inositol (myo)-1(or 4)-monophosphatase 2 Details for - - inositol (myo)-1(or 4)-monophosphatase 2 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 114663 Tuberculist Genomic Region
114714 RAD51 homolog C Details for RP23-209O5.3 - RAD51 homolog C GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 114714 Tuberculist Genomic Region	12580 cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4) Details for RP23-320F19.3 - cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4) GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 12580 Tuberculist Genomic Region
14156 flap structure specific endonuclease 1 Details for - - flap structure specific endonuclease 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 14156 Tuberculist Genomic Region	18140 ubiquitin-like, containing PHD and RING finger domains, 1 Details for - - ubiquitin-like, containing PHD and RING finger domains, 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 18140 Tuberculist Genomic Region
19361 RAD51 homolog Details for RP23-15I21.4 - RAD51 homolog GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 19361 Tuberculist Genomic Region	19363 RAD51 homolog B Details for - - RAD51 homolog B GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 19363 Tuberculist Genomic Region
19891 replication protein A2 Details for RP23-442A20.4 - replication protein A2 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 19891 Tuberculist Genomic Region	209334 Gen homolog 1, endonuclease (Drosophila) Details for - - Gen homolog 1, endonuclease (Drosophila) GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 209334 Tuberculist Genomic Region
225745 HAUS augmin-like complex, subunit 1 Details for - - HAUS augmin-like complex, subunit 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 225745 Tuberculist Genomic Region	228421 kinesin family member 18A Details for RP23-206C1.1 - kinesin family member 18A GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 228421 Tuberculist Genomic Region
237211 Fanconi anemia, complementation group B Details for RP23-132J17.2 - Fanconi anemia, complementation group B GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 237211 Tuberculist Genomic Region	23834 cell division cycle 6 Details for RP23-333D2.2 - cell division cycle 6 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 23834 Tuberculist Genomic Region
26934 Rac GTPase-activating protein 1 Details for - - Rac GTPase-activating protein 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 26934 Tuberculist Genomic Region	381101 2'-deoxynucleoside 5'-phosphate N-hydrolase 1 Details for - - 2'-deoxynucleoside 5'-phosphate N-hydrolase 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 381101 Tuberculist Genomic Region
56452 origin recognition complex, subunit 6 Details for - - origin recognition complex, subunit 6 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 56452 Tuberculist Genomic Region	623474 RAD54 homolog B (S. cerevisiae) Details for RP23-242O9.3 - RAD54 homolog B (S. cerevisiae) GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 623474 Tuberculist Genomic Region
67849 cell division cycle associated 5 Details for - - cell division cycle associated 5 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 67849 Tuberculist Genomic Region	68275 replication protein A1 Details for RP23-113D4.1 - replication protein A1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 68275 Tuberculist Genomic Region
72486 ring finger protein 219 Details for - - ring finger protein 219 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 72486 Tuberculist Genomic Region	67141 F-box protein 5 Details for - - F-box protein 5 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 67141 Tuberculist Genomic Region

TFBS DB TF

TFs	percTargets	pValue
V_E2F_Q6_01_M00920	0.5	0.0000000146

GO Terms

Displaying 1 - 1 of 1

GO Terms
NA

Upstream MEME Motif

Motif1 E-Value	Motif1 Consensus	Motif1 Matches	Motif2 E-Value	Motif2 Consensus	Motif2 Matches
1.6	TTTNNANTGWTT	NA	15	GGGGCGGGGC	SP1_MA0079.2, Klf4_MA0039.2, SP1_MA0079.1, V$SP1_Q6_01_M00931, V$SP1_Q6_M00196, V$GC_01_M00255, V$SP1_Q4_01_M00932, V$SP4_Q5_M01273, V$SP1_Q2_01_M00933, V$SP2_01_M01783, V$SP1_02_M01303, V$SP4_03_M02810, V$SP1_03_M02281, V$SP1_01_M00008, V$KROX_Q6_M00982, V$BCL6B_04_M02844, V$ETF_Q6_M00695, V$UF1H3BETA_Q6_M01068, V$ZFP281_04_M02831, V$EGR1_06_M02744, V$ZFP281_01_M01597, V$ZFP410_04_M02936, V$EGR1_Q6_M01873, V$E2F3_Q6_M02089, V$SMAD4_04_M02898, V$KLF7_03_M02773, V$ZBP89_Q4_M01816, V$CKROX_Q2_M01175, V$GKLF_02_M01588, V$MAZ_Q6_01_M02023, V$MAZR_01_M00491, V$ZFP740_03_M02834, V$SP1SP3_Q4_M01219, Sp4.1, Bcl6b.2, Egr1.1, Zfp410.1, Zfp281.2, Smad3.1, Klf7.1, Zfp740.1, Zif268.1, Sp4.2, KLF16_C2H2_DBD_monomeric_11_1, SP1_C2H2_DBD_monomeric_11_1, KLF13_C2H2_full_monomeric_18_1, SP4_C2H2_full_monomeric_17_1, KLF14_C2H2_DBD_monomeric_14_1, SP3_C2H2_DBD_monomeric_11_1, SP8_C2H2_DBD_monomeric_12_1

Upstream Weeder Motif

Motif1 Score	Motif1 Consensus	Motif1 Matches	Motif2 Score	Motif2 Consensus	Motif2 Matches
1.97	TTCGCG	V$E2F1_Q6_01_M00940, V$E2F_01_M00024, V$E2F_Q6_M00427, V$E2F_Q4_02_M00939, V$E2F_Q3_01_M00918, V$E2F1_Q6_M00431, V$E2F_Q3_M00425, V$E2F_Q4_M00426, V$E2F4DP1_01_M00738, V$E2F_Q4_01_M00919, V$E2F_02_M00050, V$E2F_03_M00516, V$E2F_Q6_01_M00920, V$E2F1DP1RB_01_M00740, V$E2F4DP2_01_M00739, V$E2F1_Q4_M00430, V$E2F1DP1_01_M00736, V$E2F1_Q3_01_M00938, V$E2F1DP2_01_M00737	2.3	TTCGCGGG	Smad3.1

3p UTR Weeder

Motif1 E-Value	Motif1 Consensus	Motif1 Matches	Motif1 Model	Motif2 E-Value	Motif2 Consensus	Motif2 Matches	Motif2 Model
0.63	GAACYG	NA	NA	0.87	GTTANNGC	NA	NA

3p UTR PITA

miRNAs	percTargets	pValue
NA

3p UTR TargetScan

miRNAs	percTargets	pValue
NA

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