PITA_72 megaCluster: 11 Residual: 0.20

Summary

Title	Cluster	Residual	Bicluster Conditions	Residual Permutation P-Value	Var. Exp. First PC	Var. Exp. First PC Perm. P-Value
PITA_72	11	0.20	15	0	0.93116	0

Members

Displaying 1 - 43 of 43

TFBS DB TF

TFs	percTargets	pValue
V_HES1_Q6_M02011	0.512821	0.00000106

GO Terms

Displaying 1 - 1 of 1

GO Terms
NA

Upstream MEME Motif

Motif1 E-Value	Motif1 Consensus	Motif1 Matches	Motif2 E-Value	Motif2 Consensus	Motif2 Matches
0.45	GGGGCGGGGC	SP1_MA0079.2, Klf4_MA0039.2, V$SP1_Q6_01_M00931, V$SP4_Q5_M01273, V$SP1_Q6_M00196, V$GC_01_M00255, V$SP1_Q4_01_M00932, V$SP1_02_M01303, V$UF1H3BETA_Q6_M01068, V$SP1_Q2_01_M00933, V$SP1_03_M02281, V$SP2_01_M01783, V$ZFP281_01_M01597, V$MAZR_01_M00491, V$ETF_Q6_M00695, V$KLF7_03_M02773, V$SP1_01_M00008, V$CKROX_Q2_M01175, V$GKLF_02_M01588, V$SP4_03_M02810, V$SP1SP3_Q4_M01219, V$E2F3_Q6_M02089, V$SMAD4_04_M02898, V$ZNF219_01_M01122, V$MAZ_Q6_01_M02023, V$BCL6B_04_M02844, V$ZBP89_Q4_M01816, V$ZFP281_04_M02831, V$EGR1_Q6_M01873, V$KROX_Q6_M00982, V$ZFP410_04_M02936, V$KLF15_Q2_M01714, V$EGR1_06_M02744, V$MAZ_Q6_M00649, V$SP4_04_M02914, Klf7.1, Sp4.1, Smad3.1, Bcl6b.2, Zfp281.2, Zfp410.1, Egr1.1, Sp4.2, Zfp740.1, SP4_C2H2_full_monomeric_17_1, SP1_C2H2_DBD_monomeric_11_1, KLF16_C2H2_DBD_monomeric_11_1, SP3_C2H2_DBD_monomeric_11_1, KLF14_C2H2_DBD_monomeric_14_1, KLF13_C2H2_full_monomeric_18_1, SP8_C2H2_DBD_monomeric_12_1, ZNF740_C2H2_full_monomeric_10_1	2	AAAAAMAAAAA	NA

Upstream Weeder Motif

Motif1 Score	Motif1 Consensus	Motif1 Matches	Motif2 Score	Motif2 Consensus	Motif2 Matches
1.5	ACCGCG	NA	1.66	GCCGCGCG	V$CNOT3_01_M01253, V$ZF5_01_M00716, Zfp161.1, Zfp161.2, E2F3.1, E2F2.1

3p UTR Weeder

Motif1 E-Value	Motif1 Consensus	Motif1 Matches	Motif1 Model	Motif2 E-Value	Motif2 Consensus	Motif2 Matches	Motif2 Model
0.67	GTTGAA	NA	NA	0.68	AGTGCGCG	NA	NA

3p UTR PITA

miRNAs	percTargets	pValue
mmu-miR-23b, mmu-miR-23a	0.709677	0.0000555

3p UTR TargetScan

miRNAs	percTargets	pValue
NA

100037258 DnaJ (Hsp40) homolog, subfamily C, member 3 Details for - - DnaJ (Hsp40) homolog, subfamily C, member 3 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 100037258 Tuberculist Genomic Region	102141 sorting nexin 25 Details for - - sorting nexin 25 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 102141 Tuberculist Genomic Region
107566 ADP-ribosylation factor-like 2 binding protein Details for - - ADP-ribosylation factor-like 2 binding protein GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 107566 Tuberculist Genomic Region	107652 UDP-N-acetylglucosamine pyrophosphorylase 1 Details for - - UDP-N-acetylglucosamine pyrophosphorylase 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 107652 Tuberculist Genomic Region
12304 protein disulfide isomerase associated 4 Details for - - protein disulfide isomerase associated 4 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 12304 Tuberculist Genomic Region	12628 complement component factor h Details for - - complement component factor h GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 12628 Tuberculist Genomic Region
13204 DEAH (Asp-Glu-Ala-His) box polypeptide 15 Details for - - DEAH (Asp-Glu-Ala-His) box polypeptide 15 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 13204 Tuberculist Genomic Region	14155 feminization 1 homolog b (C. elegans) Details for - - feminization 1 homolog b (C. elegans) GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 14155 Tuberculist Genomic Region
14423 UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 1 Details for - - UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 14423 Tuberculist Genomic Region	19684 radixin Details for - - radixin GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 19684 Tuberculist Genomic Region
20174 RuvB-like protein 2 Details for - - RuvB-like protein 2 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 20174 Tuberculist Genomic Region	20719 serine (or cysteine) peptidase inhibitor, clade B, member 6a Details for RP23-262J21.1 - serine (or cysteine) peptidase inhibitor, clade B, member 6a GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 20719 Tuberculist Genomic Region
211347 pantothenate kinase 3 Details for RP23-196B5.1 - pantothenate kinase 3 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 211347 Tuberculist Genomic Region	229317 eukaryotic translation initiation factor 2A Details for - - eukaryotic translation initiation factor 2A GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 229317 Tuberculist Genomic Region
246707 elastin microfibril interfacer 2 Details for - - elastin microfibril interfacer 2 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 246707 Tuberculist Genomic Region	269423 RIKEN cDNA 3110057O12 gene Details for - - RIKEN cDNA 3110057O12 gene GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 269423 Tuberculist Genomic Region
380629 headcase homolog (Drosophila) Details for - - headcase homolog (Drosophila) GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 380629 Tuberculist Genomic Region	56358 coatomer protein complex, subunit zeta 2 Details for RP23-353J21.4 - coatomer protein complex, subunit zeta 2 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 56358 Tuberculist Genomic Region
63959 solute carrier family 29 (nucleoside transporters), member 1 Details for - - solute carrier family 29 (nucleoside transporters), member 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 63959 Tuberculist Genomic Region	64209 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 Details for - - homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 64209 Tuberculist Genomic Region
66181 NOP10 ribonucleoprotein Details for RP23-63C10.4 - NOP10 ribonucleoprotein GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 66181 Tuberculist Genomic Region	66286 SEC11 homolog C (S. cerevisiae) Details for - - SEC11 homolog C (S. cerevisiae) GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 66286 Tuberculist Genomic Region
67420 fatty acyl CoA reductase 1 Details for - - fatty acyl CoA reductase 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 67420 Tuberculist Genomic Region	67705 RIKEN cDNA 1810058I24 gene Details for - - RIKEN cDNA 1810058I24 gene GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 67705 Tuberculist Genomic Region
68135 eukaryotic translation initiation factor 3, subunit H Details for - - eukaryotic translation initiation factor 3, subunit H GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 68135 Tuberculist Genomic Region	72201 OTU domain containing 6B Details for RP23-379L17.1 - OTU domain containing 6B GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 72201 Tuberculist Genomic Region
75292 protein kinase D3 Details for - - protein kinase D3 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 75292 Tuberculist Genomic Region	108797 mex3 homolog B (C. elegans) Details for - - mex3 homolog B (C. elegans) GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 108797 Tuberculist Genomic Region
11732 progressive ankylosis Details for - - progressive ankylosis GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 11732 Tuberculist Genomic Region	13205 DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 3, X-linked Details for RP23-158L19.4 - DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 3, X-linked GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 13205 Tuberculist Genomic Region
16548 ketohexokinase Details for - - ketohexokinase GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 16548 Tuberculist Genomic Region	22027 heat shock protein 90, beta (Grp94), member 1 Details for - - heat shock protein 90, beta (Grp94), member 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 22027 Tuberculist Genomic Region
399101 small nucleolar RNA host gene (non-protein coding) 3 Details for - - small nucleolar RNA host gene (non-protein coding) 3 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 399101 Tuberculist Genomic Region	69895 small nucleolar RNA host gene 8 Details for - - small nucleolar RNA host gene 8 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 69895 Tuberculist Genomic Region
72655 small nucleolar RNA host gene 5 Details for - - small nucleolar RNA host gene 5 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 72655 Tuberculist Genomic Region	13682 eukaryotic translation initiation factor 4A2 Details for - - eukaryotic translation initiation factor 4A2 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 13682 Tuberculist Genomic Region
195434 UTP14, U3 small nucleolar ribonucleoprotein, homolog B (yeast) Details for - - UTP14, U3 small nucleolar ribonucleoprotein, homolog B (yeast) GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 195434 Tuberculist Genomic Region	66870 serpine1 mRNA binding protein 1 Details for - - serpine1 mRNA binding protein 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 66870 Tuberculist Genomic Region
75619 FAST kinase domains 2 Details for - - FAST kinase domains 2 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 75619 Tuberculist Genomic Region	84652 family with sequence similarity 126, member A Details for - - family with sequence similarity 126, member A GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 84652 Tuberculist Genomic Region
74205 acyl-CoA synthetase long-chain family member 3 Details for - - acyl-CoA synthetase long-chain family member 3 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 74205 Tuberculist Genomic Region	16211 karyopherin (importin) beta 1 Details for RP23-81D2.3 - karyopherin (importin) beta 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 16211 Tuberculist Genomic Region
66156 anaphase promoting complex subunit 11 Details for RP23-84C12.5 - anaphase promoting complex subunit 11 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 66156 Tuberculist Genomic Region

Summary

Members

Details for - - DnaJ (Hsp40) homolog, subfamily C, member 3

Details for - - sorting nexin 25

Details for - - ADP-ribosylation factor-like 2 binding protein

Details for - - UDP-N-acetylglucosamine pyrophosphorylase 1

Details for - - protein disulfide isomerase associated 4

Details for - - complement component factor h

Details for - - DEAH (Asp-Glu-Ala-His) box polypeptide 15

Details for - - feminization 1 homolog b (C. elegans)

Details for - - UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 1

Details for - - radixin

Details for - - RuvB-like protein 2

Details for RP23-262J21.1 - serine (or cysteine) peptidase inhibitor, clade B, member 6a

Details for RP23-196B5.1 - pantothenate kinase 3

Details for - - eukaryotic translation initiation factor 2A

Details for - - elastin microfibril interfacer 2

Details for - - RIKEN cDNA 3110057O12 gene

Details for - - headcase homolog (Drosophila)

Details for RP23-353J21.4 - coatomer protein complex, subunit zeta 2

Details for - - solute carrier family 29 (nucleoside transporters), member 1

Details for - - homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1

Details for RP23-63C10.4 - NOP10 ribonucleoprotein

Details for - - SEC11 homolog C (S. cerevisiae)

Details for - - fatty acyl CoA reductase 1

Details for - - RIKEN cDNA 1810058I24 gene

Details for - - eukaryotic translation initiation factor 3, subunit H

Details for RP23-379L17.1 - OTU domain containing 6B

Details for - - protein kinase D3

Details for - - mex3 homolog B (C. elegans)

Details for - - progressive ankylosis

Details for RP23-158L19.4 - DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 3, X-linked

Details for - - ketohexokinase

Details for - - heat shock protein 90, beta (Grp94), member 1

Details for - - small nucleolar RNA host gene (non-protein coding) 3

Details for - - small nucleolar RNA host gene 8

Details for - - small nucleolar RNA host gene 5

Details for - - eukaryotic translation initiation factor 4A2

Details for - - UTP14, U3 small nucleolar ribonucleoprotein, homolog B (yeast)

Details for - - serpine1 mRNA binding protein 1

Details for - - FAST kinase domains 2

Details for - - family with sequence similarity 126, member A

Details for - - acyl-CoA synthetase long-chain family member 3

Details for RP23-81D2.3 - karyopherin (importin) beta 1

Details for RP23-84C12.5 - anaphase promoting complex subunit 11

GO Terms

3p UTR PITA