TargetScan_10 megaCluster: 2 Residual: 0.17 | Macrophage Network Portal

Summary

Title	Cluster	Residual	Bicluster Conditions	Residual Permutation P-Value	Var. Exp. First PC	Var. Exp. First PC Perm. P-Value
TargetScan_10	2	0.17	15	0	0.941729	0

Members

Displaying 1 - 26 of 26

100504139 predicted gene, 16685 Details for - - predicted gene, 16685 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 100504139 Tuberculist Genomic Region	104015 synaptojanin 1 Details for - - synaptojanin 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 104015 Tuberculist Genomic Region
109032 Sp110 nuclear body protein Details for - - Sp110 nuclear body protein GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 109032 Tuberculist Genomic Region	110521 human immunodeficiency virus type I enhancer binding protein 1 Details for - - human immunodeficiency virus type I enhancer binding protein 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 110521 Tuberculist Genomic Region
15558 5-hydroxytryptamine (serotonin) receptor 2A Details for - - 5-hydroxytryptamine (serotonin) receptor 2A GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 15558 Tuberculist Genomic Region	19088 protein kinase, cAMP dependent regulatory, type II beta Details for RP23-193M19.1 - protein kinase, cAMP dependent regulatory, type II beta GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 19088 Tuberculist Genomic Region
192198 leucine rich repeat containing 4 Details for - - leucine rich repeat containing 4 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 192198 Tuberculist Genomic Region	19734 regulator of G-protein signaling 16 Details for - - regulator of G-protein signaling 16 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 19734 Tuberculist Genomic Region
207683 immunoglobulin superfamily, member 11 Details for RP23-131M7.1 - immunoglobulin superfamily, member 11 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 207683 Tuberculist Genomic Region	225594 predicted gene 4841 Details for - - predicted gene 4841 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 225594 Tuberculist Genomic Region
27218 signaling lymphocytic activation molecule family member 1 Details for - - signaling lymphocytic activation molecule family member 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 27218 Tuberculist Genomic Region	434341 NLR family, CARD domain containing 5 Details for mCG_131283 - NLR family, CARD domain containing 5 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 434341 Tuberculist Genomic Region
52822 RUN and FYVE domain containing 3 Details for - - RUN and FYVE domain containing 3 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 52822 Tuberculist Genomic Region	54153 RAS p21 protein activator 4 Details for - - RAS p21 protein activator 4 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 54153 Tuberculist Genomic Region
56068 Alport syndrome, mental retardation, midface hypoplasia and elliptocytosis chromosomal region gene 1 Details for RP23-340M18.4 - Alport syndrome, mental retardation, midface hypoplasia and elliptocytosis chromosomal region gene 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 56068 Tuberculist Genomic Region	56318 acid phosphatase, prostate Details for 9.104100899-104272570.1 - acid phosphatase, prostate GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 56318 Tuberculist Genomic Region
64292 prostaglandin E synthase Details for RP23-221O14.6 - prostaglandin E synthase GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 64292 Tuberculist Genomic Region	68255 transmembrane protein 86B Details for - - transmembrane protein 86B GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 68255 Tuberculist Genomic Region
68267 solute carrier family 25 (mitochondrial carrier, glutamate), member 22 Details for - - solute carrier family 25 (mitochondrial carrier, glutamate), member 22 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 68267 Tuberculist Genomic Region	780818 immunoglobulin heavy variable V11-2 Details for - - immunoglobulin heavy variable V11-2 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 780818 Tuberculist Genomic Region
99382 ankyrin repeat and BTB (POZ) domain containing 2 Details for RP23-338B23.1 - ankyrin repeat and BTB (POZ) domain containing 2 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 99382 Tuberculist Genomic Region	11541 adenosine A2b receptor Details for RP23-330N10.1 - adenosine A2b receptor GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 11541 Tuberculist Genomic Region
14745 lysophosphatidic acid receptor 1 Details for RP23-170A3.2 - lysophosphatidic acid receptor 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 14745 Tuberculist Genomic Region	230779 serine incorporator 2 Details for RP23-12J1.7 - serine incorporator 2 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 230779 Tuberculist Genomic Region
71371 AT rich interactive domain 5B (MRF1-like) Details for - - AT rich interactive domain 5B (MRF1-like) GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 71371 Tuberculist Genomic Region	18037 nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, epsilon Details for - - nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, epsilon GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 18037 Tuberculist Genomic Region

TFBS DB TF

TFs	percTargets	pValue
V_SP1_Q6_M00196	1	0

GO Terms

Displaying 1 - 1 of 1

GO Terms
NA

Upstream MEME Motif

Motif1 E-Value	Motif1 Consensus	Motif1 Matches	Motif2 E-Value	Motif2 Consensus	Motif2 Matches
0.12	TTTSTTTTTTTN	NA	190	GRGGGGNGGGG	SP1_MA0079.2, Klf4_MA0039.2, V$ZFP281_01_M01597, V$SP4_Q5_M01273, V$SP1_02_M01303, V$SP1_Q2_01_M00933, V$UF1H3BETA_Q6_M01068, V$CKROX_Q2_M01175, V$GKLF_02_M01588, V$SP1_Q6_M00196, V$MAZR_01_M00491, V$SP1_Q4_01_M00932, V$SP1_03_M02281, V$MAZ_Q6_M00649, V$KLF7_03_M02773, V$SP1_Q6_01_M00931, V$ZFP281_04_M02831, V$ZBP89_Q4_M01816, V$GC_01_M00255, V$MAZ_Q6_01_M02023, V$CACD_01_M01113, V$ZNF219_01_M01122, V$EKLF_Q5_M01874, V$KLF15_Q2_M01714, V$CACBINDINGPROTEIN_Q6_M00720, V$SP1SP3_Q4_M01219, V$FKLF_Q5_M01837, V$KROX_Q6_M00982, V$BCL6B_04_M02844, V$CACCCBINDINGFACTOR_Q6_M00721, V$ZFP740_03_M02834, V$MZF1_01_M00083, V$ETF_Q6_M00695, V$NFE4_Q5_M02105, V$SMAD4_04_M02898, V$SP1_01_M00008, V$EGR2_Q6_M02092, V$ZFP410_04_M02936, V$BTEB3_Q5_M01865, V$SP4_03_M02810, Klf7.1, Zfp281.2, Bcl6b.2, Zfp740.1, Smad3.1, Zfp410.1, Sp4.1, Sox13.2, Egr1.1, Ascl2.2, Egr1.2, SP1_C2H2_DBD_monomeric_11_1, KLF16_C2H2_DBD_monomeric_11_1, ZNF740_C2H2_full_monomeric_10_1, SP3_C2H2_DBD_monomeric_11_1, SP4_C2H2_full_monomeric_17_1, SP8_C2H2_DBD_monomeric_12_1, Klf12_C2H2_DBD_monomeric_15_1, FOXO6_forkhead_DBD_putatively-multimeric_14_1, KLF14_C2H2_DBD_monomeric_14_1

Upstream Weeder Motif

Motif1 Score	Motif1 Consensus	Motif1 Matches	Motif2 Score	Motif2 Consensus	Motif2 Matches
0.93	TCGGCG	E2F3.2, E2F2.2	0.97	GCAGGGGG	Zfp740.2, Sp4.1, Zfp281.2, ZIC3_C2H2_full_monomeric_15_1, ZIC1_C2H2_full_monomeric_14_1

3p UTR Weeder

Motif1 E-Value	Motif1 Consensus	Motif1 Matches	Motif1 Model	Motif2 E-Value	Motif2 Consensus	Motif2 Matches	Motif2 Model
0.48	TGTGNG	NA	NA		NA	NA	NA

3p UTR PITA

miRNAs	percTargets	pValue
mmu-miR-196b, mmu-miR-196a	0.809524	0.00000449

3p UTR TargetScan

miRNAs	percTargets	pValue
mmu-miR-338-5p	0.5	0.0000406

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