TargetScan_122 megaCluster: 9 Residual: 0.18

Summary

Title	Cluster	Residual	Bicluster Conditions	Residual Permutation P-Value	Var. Exp. First PC	Var. Exp. First PC Perm. P-Value
TargetScan_122	9	0.18	15	0	0.94092	0

Members

Displaying 1 - 41 of 41

TFBS DB TF

TFs	percTargets	pValue
V_ZFP206_01_M01742	0.658537	0.0000037

GO Terms

Displaying 1 - 1 of 1

GO Terms
NA

Upstream MEME Motif

Motif1 E-Value	Motif1 Consensus	Motif1 Matches	Motif2 E-Value	Motif2 Consensus	Motif2 Matches
0.000000032	TTTNTTTTWTTT	NA	0.00000091	CCCCGCCCCYY	SP1_MA0079.2, Klf4_MA0039.2, SP1_MA0079.1, V$SP1_Q6_M00196, V$SP4_Q5_M01273, V$SP1_Q2_01_M00933, V$SP1_Q4_01_M00932, V$SP1_02_M01303, V$ZFP281_01_M01597, V$SP1_Q6_01_M00931, V$SP1_03_M02281, V$KLF7_03_M02773, V$GC_01_M00255, V$MAZR_01_M00491, V$GKLF_02_M01588, V$UF1H3BETA_Q6_M01068, V$CKROX_Q2_M01175, V$MAZ_Q6_M00649, V$ZFP281_04_M02831, V$KROX_Q6_M00982, V$SP4_03_M02810, V$ZNF219_01_M01122, V$BCL6B_04_M02844, V$SP1SP3_Q4_M01219, V$MAZ_Q6_01_M02023, V$ZBP89_Q4_M01816, V$SP1_01_M00008, V$SMAD4_04_M02898, V$ETF_Q6_M00695, V$E2F3_Q6_M02089, V$CACD_01_M01113, V$EGR1_Q6_M01873, V$SP2_01_M01783, V$ZFP410_04_M02936, V$EKLF_Q5_M01874, V$KLF15_Q2_M01714, V$CACBINDINGPROTEIN_Q6_M00720, V$EGR1_06_M02744, V$ZFP740_03_M02834, V$WT1_Q6_01_M02036, V$MZF1_01_M00083, V$FKLF_Q5_M01837, V$ZNF515_01_M01231, Klf7.1, Zfp281.2, Sp4.1, Bcl6b.2, Smad3.1, Zfp410.1, Egr1.1, Zfp740.1, Ascl2.2, Zif268.1, Sox13.2, SP4_C2H2_full_monomeric_17_1, KLF16_C2H2_DBD_monomeric_11_1, SP1_C2H2_DBD_monomeric_11_1, SP8_C2H2_DBD_monomeric_12_1, SP3_C2H2_DBD_monomeric_11_1, KLF14_C2H2_DBD_monomeric_14_1, ZNF740_C2H2_full_monomeric_10_1, Klf12_C2H2_DBD_monomeric_15_1, KLF13_C2H2_full_monomeric_18_1

Upstream Weeder Motif

Motif1 Score	Motif1 Consensus	Motif1 Matches	Motif2 Score	Motif2 Consensus	Motif2 Matches
1.19	CGCGAC	Zfp161.2, Max.2	1.34	GNCGCGCG	E2F2.1, Zfp161.1, E2F3.1, Zfp161.2, Max.2

3p UTR Weeder

Motif1 E-Value	Motif1 Consensus	Motif1 Matches	Motif1 Model	Motif2 E-Value	Motif2 Consensus	Motif2 Matches	Motif2 Model
0.64	CGAGCG	NA	NA	0.62	AGCNNGCC	NA	NA

3p UTR PITA

miRNAs	percTargets	pValue
NA

3p UTR TargetScan

miRNAs	percTargets	pValue
mmu-miR-1982.1	0.428571	0.00000162

107271 tyrosyl-tRNA synthetase Details for - - tyrosyl-tRNA synthetase GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 107271 Tuberculist Genomic Region	108012 adaptor-related protein complex 1, sigma 2 subunit Details for RP23-391L6.1 - adaptor-related protein complex 1, sigma 2 subunit GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 108012 Tuberculist Genomic Region
108062 cleavage stimulation factor, 3' pre-RNA subunit 2 Details for RP23-182N4.2 - cleavage stimulation factor, 3' pre-RNA subunit 2 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 108062 Tuberculist Genomic Region	108156 methylenetetrahydrofolate dehydrogenase (NADP+ dependent), methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthase Details for - - methylenetetrahydrofolate dehydrogenase (NADP+ dependent), methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthase GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 108156 Tuberculist Genomic Region
109689 arrestin, beta 1 Details for - - arrestin, beta 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 109689 Tuberculist Genomic Region	170707 ubiquitin specific peptidase 48 Details for RP23-277N22.2 - ubiquitin specific peptidase 48 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 170707 Tuberculist Genomic Region
20148 dehydrogenase/reductase (SDR family) member 3 Details for RP23-133N19.1 - dehydrogenase/reductase (SDR family) member 3 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 20148 Tuberculist Genomic Region	216190 adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 2 Details for - - adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 2 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 216190 Tuberculist Genomic Region
22644 ring finger protein 103 Details for - - ring finger protein 103 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 22644 Tuberculist Genomic Region	232853 zinc finger protein 954 Details for - - zinc finger protein 954 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 232853 Tuberculist Genomic Region
234797 RIKEN cDNA 6430548M08 gene Details for - - RIKEN cDNA 6430548M08 gene GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 234797 Tuberculist Genomic Region	329727 DENN/MADD domain containing 2C Details for - - DENN/MADD domain containing 2C GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 329727 Tuberculist Genomic Region
333433 glycerol-3-phosphate dehydrogenase 1-like Details for - - glycerol-3-phosphate dehydrogenase 1-like GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 333433 Tuberculist Genomic Region	52665 enoyl Coenzyme A hydratase domain containing 1 Details for - - enoyl Coenzyme A hydratase domain containing 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 52665 Tuberculist Genomic Region
66659 acid phosphatase 6, lysophosphatidic Details for - - acid phosphatase 6, lysophosphatidic GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 66659 Tuberculist Genomic Region	66834 acyl-CoA thioesterase 13 Details for RP23-92G13.5 - acyl-CoA thioesterase 13 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 66834 Tuberculist Genomic Region
70750 3-ketodihydrosphingosine reductase Details for - - 3-ketodihydrosphingosine reductase GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 70750 Tuberculist Genomic Region	74478 sorting nexin 29 Details for - - sorting nexin 29 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 74478 Tuberculist Genomic Region
77065 integrator complex subunit 7 Details for - - integrator complex subunit 7 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 77065 Tuberculist Genomic Region	83429 cystinosis, nephropathic Details for RP23-263M10.9 - cystinosis, nephropathic GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 83429 Tuberculist Genomic Region
97487 CKLF-like MARVEL transmembrane domain containing 4 Details for - - CKLF-like MARVEL transmembrane domain containing 4 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 97487 Tuberculist Genomic Region	110750 chromosome segregation 1-like (S. cerevisiae) Details for RP23-19L12.9 - chromosome segregation 1-like (S. cerevisiae) GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 110750 Tuberculist Genomic Region
13478 dolichyl-phosphate (UDP-N-acetylglucosamine) acetylglucosaminephosphotransferase 1 (GlcNAc-1-P transferase) Details for - - dolichyl-phosphate (UDP-N-acetylglucosamine) acetylglucosaminephosphotransferase 1 (GlcNAc-1-P transferase) GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 13478 Tuberculist Genomic Region	14251 flotillin 1 Details for - - flotillin 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 14251 Tuberculist Genomic Region
15925 insulin degrading enzyme Details for - - insulin degrading enzyme GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 15925 Tuberculist Genomic Region	16498 potassium voltage-gated channel, shaker-related subfamily, beta member 2 Details for RP23-421E12.12-005 - potassium voltage-gated channel, shaker-related subfamily, beta member 2 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 16498 Tuberculist Genomic Region
18744 praja1, RING-H2 motif containing Details for RP23-414J22.4 - praja1, RING-H2 motif containing GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 18744 Tuberculist Genomic Region	19714 REV3-like, catalytic subunit of DNA polymerase zeta RAD54 like (S. cerevisiae) Details for - - REV3-like, catalytic subunit of DNA polymerase zeta RAD54 like (S. cerevisiae) GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 19714 Tuberculist Genomic Region
211389 sulfite oxidase Details for - - sulfite oxidase GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 211389 Tuberculist Genomic Region	226432 importin 9 Details for - - importin 9 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 226432 Tuberculist Genomic Region
229473 RIKEN cDNA D930015E06 gene Details for - - RIKEN cDNA D930015E06 gene GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 229473 Tuberculist Genomic Region	330361 GC-rich sequence DNA binding factor 2 Details for - - GC-rich sequence DNA binding factor 2 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 330361 Tuberculist Genomic Region
66881 prenylcysteine oxidase 1 Details for - - prenylcysteine oxidase 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 66881 Tuberculist Genomic Region	67054 phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoribosylaminoimidazole, succinocarboxamide synthetase Details for - - phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoribosylaminoimidazole, succinocarboxamide synthetase GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 67054 Tuberculist Genomic Region
73341 Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6 Details for RP23-372E6.1 - Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 73341 Tuberculist Genomic Region	98732 RAB3 GTPase activating protein subunit 2 Details for - - RAB3 GTPase activating protein subunit 2 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 98732 Tuberculist Genomic Region
242474 transmembrane protein 245 Details for RP23-455B1.3 - transmembrane protein 245 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 242474 Tuberculist Genomic Region	320528 vacuolar protein sorting 13C (yeast) Details for - - vacuolar protein sorting 13C (yeast) GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 320528 Tuberculist Genomic Region
108911 regulator of chromosome condensation 2 Details for RP23-275J10.2 - regulator of chromosome condensation 2 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 108911 Tuberculist Genomic Region	238505 5-methyltetrahydrofolate-homocysteine methyltransferase Details for - - 5-methyltetrahydrofolate-homocysteine methyltransferase GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 238505 Tuberculist Genomic Region
54486 hematopoietic prostaglandin D synthase Details for - - hematopoietic prostaglandin D synthase GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 54486 Tuberculist Genomic Region

TargetScan_122 megaCluster: 9 Residual: 0.18

Summary

Members

Details for - - tyrosyl-tRNA synthetase

Details for RP23-391L6.1 - adaptor-related protein complex 1, sigma 2 subunit

Details for RP23-182N4.2 - cleavage stimulation factor, 3' pre-RNA subunit 2

Details for - - methylenetetrahydrofolate dehydrogenase (NADP+ dependent), methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthase

Details for - - arrestin, beta 1

Details for RP23-277N22.2 - ubiquitin specific peptidase 48

Details for RP23-133N19.1 - dehydrogenase/reductase (SDR family) member 3

Details for - - adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 2

Details for - - ring finger protein 103

Details for - - zinc finger protein 954

Details for - - RIKEN cDNA 6430548M08 gene

Details for - - DENN/MADD domain containing 2C

Details for - - glycerol-3-phosphate dehydrogenase 1-like

Details for - - enoyl Coenzyme A hydratase domain containing 1

Details for - - acid phosphatase 6, lysophosphatidic

Details for RP23-92G13.5 - acyl-CoA thioesterase 13

Details for - - 3-ketodihydrosphingosine reductase

Details for - - sorting nexin 29

Details for - - integrator complex subunit 7

Details for RP23-263M10.9 - cystinosis, nephropathic

Details for - - CKLF-like MARVEL transmembrane domain containing 4

Details for RP23-19L12.9 - chromosome segregation 1-like (S. cerevisiae)

Details for - - dolichyl-phosphate (UDP-N-acetylglucosamine) acetylglucosaminephosphotransferase 1 (GlcNAc-1-P transferase)

Details for - - flotillin 1

Details for - - insulin degrading enzyme

Details for RP23-421E12.12-005 - potassium voltage-gated channel, shaker-related subfamily, beta member 2

Details for RP23-414J22.4 - praja1, RING-H2 motif containing

Details for - - REV3-like, catalytic subunit of DNA polymerase zeta RAD54 like (S. cerevisiae)

Details for - - sulfite oxidase

Details for - - importin 9

Details for - - RIKEN cDNA D930015E06 gene

Details for - - GC-rich sequence DNA binding factor 2

Details for - - prenylcysteine oxidase 1

Details for - - phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoribosylaminoimidazole, succinocarboxamide synthetase

Details for RP23-372E6.1 - Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6

Details for - - RAB3 GTPase activating protein subunit 2

Details for RP23-455B1.3 - transmembrane protein 245

Details for - - vacuolar protein sorting 13C (yeast)

Details for RP23-275J10.2 - regulator of chromosome condensation 2

Details for - - 5-methyltetrahydrofolate-homocysteine methyltransferase

Details for - - hematopoietic prostaglandin D synthase

GO Terms

3p UTR PITA