TargetScan_129 megaCluster: 8 Residual: 0.13 | Macrophage Network Portal

Summary

Title	Cluster	Residual	Bicluster Conditions	Residual Permutation P-Value	Var. Exp. First PC	Var. Exp. First PC Perm. P-Value
TargetScan_129	8	0.13	15	0	0.971046	0

Members

Displaying 1 - 18 of 18

11545 poly (ADP-ribose) polymerase family, member 1 Details for - - poly (ADP-ribose) polymerase family, member 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 11545 Tuberculist Genomic Region	17535 meiotic recombination 11 homolog A (S. cerevisiae) Details for RP23-149D5.3 - meiotic recombination 11 homolog A (S. cerevisiae) GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 17535 Tuberculist Genomic Region
238831 peptidylprolyl isomerase domain and WD repeat containing 1 Details for - - peptidylprolyl isomerase domain and WD repeat containing 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 238831 Tuberculist Genomic Region	72519 transmembrane protein 55A Details for RP23-379L17.2 - transmembrane protein 55A GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 72519 Tuberculist Genomic Region
73668 tetratricopeptide repeat domain 21B Details for RP23-353H5.2 - tetratricopeptide repeat domain 21B GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 73668 Tuberculist Genomic Region	13360 7-dehydrocholesterol reductase Details for - - 7-dehydrocholesterol reductase GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 13360 Tuberculist Genomic Region
14651 hydroxyacyl glutathione hydrolase Details for - - hydroxyacyl glutathione hydrolase GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 14651 Tuberculist Genomic Region	16558 kinesin family member 16B Details for RP23-442B16.1 - kinesin family member 16B GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 16558 Tuberculist Genomic Region
211586 transcription factor Dp 2 Details for - - transcription factor Dp 2 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 211586 Tuberculist Genomic Region	212514 spindle and centriole associated protein 1 Details for - - spindle and centriole associated protein 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 212514 Tuberculist Genomic Region
216134 pyridoxal (pyridoxine, vitamin B6) kinase Details for - - pyridoxal (pyridoxine, vitamin B6) kinase GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 216134 Tuberculist Genomic Region	22156 tuftelin 1 Details for - - tuftelin 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 22156 Tuberculist Genomic Region
66622 ubiquitin protein ligase E3 component n-recognin 7 (putative) Details for - - ubiquitin protein ligase E3 component n-recognin 7 (putative) GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 66622 Tuberculist Genomic Region	68259 intraflagellar transport 80 Details for - - intraflagellar transport 80 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 68259 Tuberculist Genomic Region
71085 Rho GTPase activating protein 19 Details for - - Rho GTPase activating protein 19 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 71085 Tuberculist Genomic Region	71710 leucine rich repeat and coiled-coil domain containing 1 Details for - - leucine rich repeat and coiled-coil domain containing 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 71710 Tuberculist Genomic Region
72050 KDEL (Lys-Asp-Glu-Leu) containing 1 Details for - - KDEL (Lys-Asp-Glu-Leu) containing 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 72050 Tuberculist Genomic Region	76044 non-SMC condensin II complex, subunit G2 Details for - - non-SMC condensin II complex, subunit G2 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 76044 Tuberculist Genomic Region

TFBS DB TF

TFs	percTargets	pValue
V_SP1_Q6_01_M00931, SP1_MA0079.2, V_SP1_03_M02281, V_SP1_Q6_M00196, V_SP4_Q5_M01273, V_SP1_Q2_01_M00933, V_SP1_Q4_01_M00932	1, 1, 1, 1, 1, 1, 1	0

GO Terms

Displaying 1 - 1 of 1

GO Terms
NA

Upstream MEME Motif

Motif1 E-Value	Motif1 Consensus	Motif1 Matches	Motif2 E-Value	Motif2 Consensus	Motif2 Matches
0.0002	AGGGGCGGNGC	Klf4_MA0039.2, SP1_MA0079.2, V$SP1_Q6_01_M00931, V$SP1_Q6_M00196, V$GC_01_M00255, V$SP1_Q4_01_M00932, V$SP4_Q5_M01273, V$SP1_Q2_01_M00933, V$SP1_02_M01303, V$KLF7_03_M02773, V$ETF_Q6_M00695, V$GKLF_02_M01588, V$SP1_01_M00008, V$BCL6B_04_M02844, V$SMAD4_04_M02898, V$SP4_03_M02810, V$SP1_03_M02281, V$SP2_01_M01783, V$MAZR_01_M00491, V$E2F3_Q6_M02089, V$ZFP281_01_M01597, V$ZFP410_04_M02936, V$UF1H3BETA_Q6_M01068, V$SP1SP3_Q4_M01219, V$MAZ_Q6_01_M02023, V$KROX_Q6_M00982, V$CKROX_Q2_M01175, V$EGR1_Q6_M01873, V$EGR1_06_M02744, V$ZBP89_Q4_M01816, Klf7.1, Bcl6b.2, Sp4.1, Smad3.1, Zfp410.1, Egr1.1, Sp4.2, Zfp281.2, Zfp740.1, KLF13_C2H2_full_monomeric_18_1, SP1_C2H2_DBD_monomeric_11_1, SP4_C2H2_full_monomeric_17_1, KLF16_C2H2_DBD_monomeric_11_1, KLF14_C2H2_DBD_monomeric_14_1, SP3_C2H2_DBD_monomeric_11_1	1.4	GAAGAAAATG	NA

Upstream Weeder Motif

Motif1 Score	Motif1 Consensus	Motif1 Matches	Motif2 Score	Motif2 Consensus	Motif2 Matches
1.54	GACGCG	NA	2.13	TCGCGGGT	NA

3p UTR Weeder

Motif1 E-Value	Motif1 Consensus	Motif1 Matches	Motif1 Model	Motif2 E-Value	Motif2 Consensus	Motif2 Matches	Motif2 Model
0.74	TCTACT	NA	NA	0.92	AGGTTTCA	NA	NA

3p UTR PITA

miRNAs	percTargets	pValue
NA

3p UTR TargetScan

miRNAs	percTargets	pValue
mmu-miR-101b	0.333333	0.00000577

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